Maxwell C Coyle, Adia M Tajima, Fredrick Leon, Semil P Choksi, Ally Yang, Sarah Espinoza, Timothy R Hughes, Jeremy F Reiter, David S Booth, Nicole King
Cilia allowed our protistan ancestors to sense and explore their environment, avoid predation, and capture bacterial prey.1 , 2 , 3 Regulated ciliogenesis was likely critical for early animal evolution,2 , 4 , 5 , 6 and in modern animals, deploying cilia in the right cells at the right time is crucial for development and physiology. Two transcription factors, RFX and FoxJ1, coordinate ciliogenesis in animals7 , 8 , 9 but are absent from the genomes of many other ciliated eukaryotes, raising the question of how the regulation of ciliogenesis in animals evolved...
September 11, 2023: Current Biology: CB