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Palliative pain

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https://www.readbyqxmd.com/read/28532140/effective-treatment-of-cervical-lymph-node-metastasis-of-breast-cancer-by-low-voltage-high-frequency-electrochemotherapy
#1
Bahram Mofid, Zeinab Shankayi, Kambiz Novin, Sadegh Dehghani, Morteza Shankayi, Hamidreza Haghighatkhah, S Mohammad Firoozabadi
Electrochemotherapy (ECT) is a new local treatment method for solid and superficial tumors. During this new technique, patients experience an unpleasant sensation and slight edema. Most unpleasant and painful is mainly attributed to muscle contractions provoked by high amplitude and low repetition frequency pulses. Recently, we showed that electrochemotherapy using low voltage and higher repetition frequency (LVHF ECT) is an effective tool for inhibiting tumor growth and inducing cell permeabilization. Low voltage high-frequency electrochemotherapy was developed and optimized in vitro and in vivo which and can be used in the clinic...
April 2017: Acta Medica Iranica
https://www.readbyqxmd.com/read/28524711/the-will-to-live-breast-cancer-patients-perceptions-of-palliative-chemotherapy
#2
Jenny Bergqvist, Peter Strang
BACKGROUND: For women with metastatic breast cancer, late lines of chemotherapy might be beneficial but also harmful. Ongoing chemotherapy late in life increase the risk of late or absent discussions of palliative care and access to symptom relief by other options than chemotherapy. Our aim was, therefore, to investigate breast cancer patients' motives, perceptions, and experiences of late lines of palliative oncologic treatment. MATERIAL AND METHODS: A qualitative study with semi-guided face-to-face interviews with 20 women on at least their second line of palliative chemotherapy (second-eighth line)...
May 19, 2017: Acta Oncologica
https://www.readbyqxmd.com/read/28521551/systematic-reviews-published-in-the-cochrane-library-january-march-2017
#3
Phillip J Wiffen
The Cochrane Library of Systematic Reviews is now only published monthly online ( http://www.thecochranelibrary.com ). The methods for searching have changed and are in flux. This report attempted to identify all relevant reviews published in the last 3 months to March 30, 2017. The current version contains 7243 complete reviews and 2544 protocols for reviews in production. In addition, there are citations of 1,036,153 randomized controlled trials (first time passing the million mark) and 15,700 cited papers in the Cochrane Methodology Register...
May 19, 2017: Journal of Pain & Palliative Care Pharmacotherapy
https://www.readbyqxmd.com/read/28516110/large-bowel-obstruction-following-endoscopic-spray-cryotherapy-for-palliation-of-rectal-cancer-bleeding
#4
Ravi Prakash, Digant Gupta, Pankaj Vashi
We report a unique case of a 79-year-old woman with metastatic rectal cancer who developed bowel obstruction following endoscopic cryotherapy with liquid nitrogen for palliation of bleeding in the rectum. She developed abdominal distention and pain following the procedure. Computed tomography of the abdomen revealed a paraumbilical hernia containing a segment of transverse colon resulting in partial bowel obstruction. It appears that the recurrent freeze-thaw cycles with poor decompression of the colon despite active venting suction during cryotherapy may have resulted in bowel distention and collapse, causing conformational changes resulting in partial bowel obstruction due to a paraumbilical hernia...
2017: ACG Case Reports Journal
https://www.readbyqxmd.com/read/28515919/programmed-death-ligand-1-expression-is-associated-with-fibrosarcomatous-transformation-of-dermatofibrosarcoma-protuberans
#5
Kenji Tsuchihashi, Hitoshi Kusaba, Yuichi Yamada, Yuta Okumura, Hozumi Shimokawa, Masato Komoda, Keita Uchino, Tomoyasu Yoshihiro, Nobuhiro Tsuruta, Fumiyasu Hanamura, Kyoko Inadomi, Mamoru Ito, Kosuke Sagara, Michitaka Nakano, Kenta Nio, Shuji Arita, Hiroshi Ariyama, Kenichi Kohashi, Ryuji Tominaga, Yoshinao Oda, Koichi Akashi, Eishi Baba
Dermatofibrosarcoma protuberans (DFSP) is a locally invading tumor, characterized by the presence of the collagen type I α 1 (COL1A1)-platelet-derived growth factor (PDGF) β fusion gene. We herein report the case of a 31-year-old man with a history of resection of an abdominal wall DFSP. The patient presented with chest pain and a computed tomography scan revealed a large mass in the posterior mediastinum and another mass in the right lung. The mediastinal mass was a sarcomatous lesion expressing the COL1A1-PDGFβ fusion gene, suggesting that it represented a metastasis of the DFSP following fibrosarcomatous (FS) transformation...
May 2017: Molecular and Clinical Oncology
https://www.readbyqxmd.com/read/28515817/systematic-review-of-the-potential-role-of-cannabinoids-as-antiproliferative-agents-for-urological-cancers
#6
REVIEW
Shreyas Gandhi, Gaurav Vasisth, Anil Kapoor
INTRODUCTION: The palliative effects of cannabis sativa (marijuana), which include appetite stimulation, attenuation of nausea and emesis, and pain relief, are well known. The active components of cannabis sativa (cannabinoids) and their derivatives have received growing interest due to their diverse pharmacological activities, such as cell growth inhibition and tumour regression. The aim of this review is to look at the current evidence on the antiproliferative effects of cannabinoids in urological malignancies, including renal, prostate, bladder, and testicular cancers...
March 2017: Canadian Urological Association Journal, Journal de L'Association des Urologues du Canada
https://www.readbyqxmd.com/read/28508278/physiotherapy-programme-reduces-fatigue-in-patients-with-advanced-cancer-receiving-palliative-care-randomized-controlled-trial
#7
Anna Pyszora, Jacek Budzyński, Agnieszka Wójcik, Anna Prokop, Małgorzata Krajnik
PURPOSE: Cancer-related fatigue (CRF) is a common and relevant symptom in patients with advanced cancer that significantly decreases their quality of life. The aim of this study was to evaluate the effect of a physiotherapy programme on CRF and other symptoms in patients diagnosed with advanced cancer. METHODS: The study was designed as a randomized controlled trial. Sixty patients diagnosed with advanced cancer receiving palliative care were randomized into two groups: the treatment group (n = 30) and the control group (n = 30)...
May 16, 2017: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
https://www.readbyqxmd.com/read/28507988/comparative-therapeutic-efficacy-of-153-sm-edtmp-and-177-lu-edtmp-for-bone-pain-palliation-in-patients-with-skeletal-metastases-patients-pain-score-analysis-and-personalized-dosimetry
#8
Sarika Sharma, Baljinder Singh, Ashwani Koul, Bhagwant Rai Mittal
INTRODUCTION: The aim of the present study was to compare the therapeutic efficacy of (153)Sm-EDTMP and (177)Lu-EDTMP in pain palliation in cancer patients with skeletal metastases. MATERIALS AND METHODS: Thirty patients (25 M:5 F, mean age: 66.0 ± 14.7 years) of breast/prostate cancer with documented skeletal metastases were recruited prospectively. Twenty patients were considered randomly for treatment with (153)Sm-EDTMP and with (177)Lu-EDTMP in 10 patients, respectively...
2017: Frontiers in Medicine
https://www.readbyqxmd.com/read/28505697/-the-development-of-palliative-care-hospital-support-teams-hpcts-in-bavaria-from-2011-2015-tasks-acceptance-structure-and-funding
#9
Johanna Anneser, Tamara Thurn, Gian Domenico Borasio
Introduction Palliative care hospital support teams (HPCTs) provide inpatients from all departments palliative medical support. Seriously ill as well as dying patients, who are being treated in facilities that do not have their own palliative care unit, can benefit from these multi-professional teams just as much as patients who do not (yet) need to be admitted to a palliative care unit. At the end of 2015, 53 HPCTs, which were in accordance with the requirements established in the "Program for HPCTs" by the Bavarian Ministry of Health in 2009, had been approved in Bavaria...
May 15, 2017: Das Gesundheitswesen
https://www.readbyqxmd.com/read/28505689/-pain-management-in-palliative-care
#10
Martin B Steins, Corinna Eschbach, Matthias Villalobos, Michael Thomas
A consistent pain management together with treatment of dyspnoea belongs to the main issues in symptom control in particular in palliative thoracic oncology. Together with the medicamentous therapy the psychologic and social circumstances of the affected patients have to be considered as factors influencing the experience of pain. The therapeutic fundament according to the WHO guideline for cancer pain is the opiate based medicamentous adjustment combined with non-opioids. In principle, this should be performed preferably orally, as simply as possible, according to a fix drug schedule and individually adjusted to the needed dosage...
May 2017: Pneumologie
https://www.readbyqxmd.com/read/28503990/assessing-the-utilization-of-radiotherapy-near-end-of-life-at-a-finnish-university-hospital-a-retrospective-cohort-study
#11
Liisa K Rautakorpi, Johanna M Mäkelä, Fatemeh Seyednasrollah, Anna M Hammais, Tarja Laitinen, Outi M Hirvonen, Heikki Minn, Laura L Elo, Sirkku M Jyrkkiö
BACKGROUND: Palliative radiotherapy can improve quality of life for cancer patients during the last months of life. However, very short life expectancy may devastate the benefit of the treatment. This single center study assesses the utilization of radiotherapy during the last weeks of life. MATERIAL AND METHODS: All cancer patients (N = 38,982) treated with radiotherapy (N = 11,395) in Turku University Central Hospital during 2005-2013 were identified in the database consisting of electronic patient records...
May 13, 2017: Acta Oncologica
https://www.readbyqxmd.com/read/28503043/integration-of-specialized-pain-control-services-in-palliative-care-a-nationwide-web-based-survey
#12
Nivedita Dilip Page
INTRODUCTION: Pain control is an important part of palliative care (PC), and conventional analgesics do not provide adequate pain relief to all patients. Many patients present with complex pain syndromes that require interventional pain control measures usually deployed by pain specialists. There is adequate integration of specialized pain control services with PC elsewhere, but information about the same in our country is lacking. MATERIALS AND METHODS: An internet survey was conducted among palliative specialists regarding the need and availability of pain specialists for their patients suffering from complex pain syndromes...
April 2017: Indian Journal of Palliative Care
https://www.readbyqxmd.com/read/28503040/recommendations-to-support-nurses-and-improve-the-delivery-of-oncology-and-palliative-care-in-india
#13
Virginia T LeBaron, Gayatri Palat, Sudha Sinha, Sanjeeva Kumari Chinta, Beaulah John Battula Jamima, Usha Lakshmi Pilla, Nireekshana Podduturi, Yadamma Shapuram, Padma Vennela, Vineela Rapelli, Zahra Lalani, Susan L Beck
CONTEXT: Nurses in India often practice in resource-constrained settings and care for cancer patients with high symptom burden yet receive little oncology or palliative care training. AIM: The aim of this study is to explore challenges encountered by nurses in India and offer recommendations to improve the delivery of oncology and palliative care. METHODS: Qualitative ethnography. SETTING: The study was conducted at a government cancer hospital in urban South India...
April 2017: Indian Journal of Palliative Care
https://www.readbyqxmd.com/read/28503039/the-possible-role-of-meditation-in-myofascial-pain-syndrome-a-new-hypothesis
#14
Prashanth Panta
BACKGROUND OF HYPOTHESIS: Myofascial pain syndrome (MPS) is the most common musculoskeletal pain disorder of the head and neck area. In the past, several theories were put forth to explain its origin and nature, but none proved complete. Myofascial pain responds to changing psychological states and stress, anxiety, lack of sleep, anger, depression and chronic pain are direct contributional factors. Myofascial pain syndrome may be considered as a psychosomatic disorder. There are numerous accepted palliative approaches, but of all, relaxation techniques stand out and initiate healing at the base level...
April 2017: Indian Journal of Palliative Care
https://www.readbyqxmd.com/read/28501792/healing-ministry-and-palliative-care-in-christianity
#15
S Stephen Jayard, Nishant A Irudayadason, J Charles Davis
Death is inevitable, but that does not mean it can be planned or imposed. It is an ethical imperative that we attend to the unbearable pain and suffering of patients with incurable and terminal illnesses. This is where palliative care plays a vital role. Palliative care has been growing faster in the world of medicine since its emergence as a specialty in the last decade. Palliative care helps to reduce physical pain while affirming the aspect of human suffering and dying as a normal process. The goal of palliative care is to improve the quality of life both of the patient and the family...
May 3, 2017: Indian Journal of Medical Ethics
https://www.readbyqxmd.com/read/28501039/symptomatic-control-in-end-of-life-patients
#16
REVIEW
Mariana Alves, Rita Abril, Isabel Galriça Neto
End-of-life patients present a variety of symptoms that cause suffering for them and their respective families. Health professionals throughout their university, internship and medical careers are ill-prepared to manage and improve the quality of life of these patients. This article aims to provide basic skills in the symptomatic management of end-of-life patients, focusing in particular on the control of pain, dyspnoea, fatigue, nausea, vomiting and anorexia. It also aims to draw attention to basic concepts of control concerning refractory symptoms and palliative sedation...
January 31, 2017: Acta Médica Portuguesa
https://www.readbyqxmd.com/read/28497213/bone-pain-and-muscle-weakness-in-cancer-patients
#17
REVIEW
Daniel P Milgrom, Neha L Lad, Leonidas G Koniaris, Teresa A Zimmers
PURPOSE OF REVIEW: In this article, we will discuss the current understanding of bone pain and muscle weakness in cancer patients. We will describe the underlying physiology and mechanisms of cancer-induced bone pain (CIBP) and cancer-induced muscle wasting (CIMW), as well as current methods of diagnosis and treatment. We will discuss future therapies and research directions to help patients with these problems. RECENT FINDINGS: There are several pharmacologic therapies that are currently in preclinical and clinical testing that appear to be promising adjuncts to current CIBP and CIMW therapies...
May 11, 2017: Current Osteoporosis Reports
https://www.readbyqxmd.com/read/28495482/-recurrence-of-a-glassy-cell-carcinoma-of-the-vagina-an-exceptional-situation
#18
Y Yahiaoui, A Gabsi, R Doghri, M Ayadi, K Mrad, A Mezlini
Glassy cell carcinoma is a rare neoplasm that occurs most frequently in the uterine cervix. We describe the second reported case of glassy cell carcinoma arising in the vagina. We present a case of a 24-year-old woman with a history of post-coïtal bleeding associated with menometrorrhagia. Different explorations have concluded in a glassy cell carcinoma arising in the vagina, with clinical staging III according to the International Federation of Obstetrics and Gynecology. The patient received three cycles of neoadjuvant chemotherapy with a good response...
May 8, 2017: Cancer Radiothérapie: Journal de la Société Française de Radiothérapie Oncologique
https://www.readbyqxmd.com/read/28494643/randomised-clinical-trial-of-early-specialist-palliative-care-plus-standard-care-versus-standard-care-alone-in-patients-with-advanced-cancer-the-danish-palliative-care-trial
#19
Mogens Groenvold, Morten Aagaard Petersen, Anette Damkier, Mette Asbjoern Neergaard, Jan Bjoern Nielsen, Lise Pedersen, Per Sjøgren, Annette Sand Strömgren, Tove Bahn Vejlgaard, Christian Gluud, Jane Lindschou, Peter Fayers, Irene J Higginson, Anna Thit Johnsen
BACKGROUND: Beneficial effects of early palliative care have been found in advanced cancer, but the evidence is not unequivocal. AIM: To investigate the effect of early specialist palliative care among advanced cancer patients identified in oncology departments. SETTING/PARTICIPANTS: The Danish Palliative Care Trial (DanPaCT) (ClinicalTrials.gov NCT01348048) is a multicentre randomised clinical trial comparing early referral to a specialist palliative care team plus standard care versus standard care alone...
May 1, 2017: Palliative Medicine
https://www.readbyqxmd.com/read/28489713/denervation-of-the-wrist-joint-for-the-management-of-chronic-pain
#20
R Kumar Kadiyala, Joseph M Lombardi
Wrist denervation for the management of chronic wrist pain is a safe and effective procedure that can delay or eliminate the need for more invasive and kinematically compromising salvage procedures. Wrist denervation has become increasingly popular since it was first described in 1959, and the technique has evolved from more extensive denervations to limited single-incision approaches. Many physicians have performed this procedure as a palliative approach to managing chronic wrist pain and as an adjunct to other procedures...
June 2017: Journal of the American Academy of Orthopaedic Surgeons
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