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https://www.readbyqxmd.com/read/29764218/coping-with-shift-work-related-circadian-disruption-a-mixed-methods-case-study-on-napping-and-caffeine-use-in-australian-nurses-and-midwives
#1
Stephanie Centofanti, Siobhan Banks, Antonietta Colella, Caroline Dingle, Lisa Devine, Helen Galindo, Sophie Pantelios, Gorjana Brkic, Jillian Dorrian
INTRODUCTION: Two of the most ubiquitous fatigue countermeasures used by shift-working nurses are napping and caffeine. This mixed-methods case study investigated the ways nurses and midwives utilised napping and caffeine countermeasures to cope with shift work, and associated sleep, physical health and psychological health outcomes. MATERIALS AND METHODS: N = 130 Australian shift-working nurses and midwives (mean age = 44 years, range = 21-67, 115F, 15M) completed the Standard Shiftwork Index...
May 15, 2018: Chronobiology International
https://www.readbyqxmd.com/read/29673432/a-survey-of-fatigue-in-army-aviators
#2
Amanda M Kelley, Kathryn A Feltman, Ian P Curry
INTRODUCTION: Fatigue plays a critical role in mission success due to its effect on a number of performance variables. The purpose of this study was to gauge the extent to which U.S. Army aviators experience subjective fatigue on a regular basis presently as well as their perceptions of their own sleep quality, quantity, and daytime sleepiness. This information is valuable for prioritizing future research lines with respect to injury prevention and fatigue management as well as updating policy...
May 1, 2018: Aerospace Medicine and Human Performance
https://www.readbyqxmd.com/read/29607311/shiftwork-mediated-disruptions-of-circadian-rhythms-and-sleep-homeostasis-cause-serious-health-problems
#3
REVIEW
Suliman Khan, Pengfei Duan, Lunguang Yao, Hongwei Hou
Shiftwork became common during the last few decades with the growing demands of human life. Despite the social inactivity and irregularity in habits, working in continuous irregular shifts causes serious health issues including sleep disorders, psychiatric disorders, cancer, and metabolic disorders. These health problems arise due to the disruption in circadian clock system, which is associated with alterations in genetic expressions. Alteration in clock controlling genes further affects genes linked with disorders including major depression disorder, bipolar disorder, phase delay and phase advance sleep syndromes, breast cancer, and colon cancer...
2018: International Journal of Genomics
https://www.readbyqxmd.com/read/29593783/perinatal-programming-of-circadian-clock-stress-crosstalk
#4
REVIEW
Mariana Astiz, Henrik Oster
An intact communication between circadian clocks and the stress system is important for maintaining physiological homeostasis under resting conditions and in response to external stimuli. There is accumulating evidence for a reciprocal interaction between both-from the systemic to the molecular level. Disruption of this interaction by external factors such as shiftwork, jetlag, or chronic stress increases the risk of developing metabolic, immune, or mood disorders. From experiments in rodents, we know that both systems maturate during the perinatal period...
2018: Neural Plasticity
https://www.readbyqxmd.com/read/29480763/an-exploration-of-shift-work-fatigue-and-gender-among-police-officers-the-bcops-study
#5
John M Violanti, Sherry L Owens, Desta Fekedulegn, Claudia C Ma, Luenda E Charles, Michael E Andrew
The present study examined the association between shift work and fatigue among male ( n = 230) and female ( n = 78) police officers. A 15-year work history database was used to define dominant shifts as day, afternoon, or night. A 10-item questionnaire created from the Standard Shiftwork Index (SSI) assessed fatigue. Gender-stratified analyses of variance and covariance and Poisson regression were used to compare means and prevalence of individual items across shifts. No significant differences in total fatigue scores were observed across shifts...
February 1, 2018: Workplace Health & Safety
https://www.readbyqxmd.com/read/29438001/association-between-shiftwork-and-the-risk-of-colorectal-cancer-in-females-a-population-based-case-control-study
#6
Wa Mwenga Walasa, Renee N Carey, Si Si, Lin Fritschi, Jane S Heyworth, Renae C Fernandez, Terry Boyle
OBJECTIVE: Research indicates that shiftwork may be associated with increased risks of adverse health outcomes, including some cancers. However, the evidence of an association between shiftwork and colorectal cancer risk is limited and inconclusive. Further, while several possible pathways through which shiftwork might result in cancer have been proposed, few studies have taken these factors into account. We investigated the association between two types of shiftwork (graveyard shiftwork and early-morning shiftwork) and six mechanistic shiftwork variables (including light at night and phase shift) and the risk of colorectal cancer among females in an Australian population-based case-control study...
May 2018: Occupational and Environmental Medicine
https://www.readbyqxmd.com/read/29437238/a-unified-model-of-melatonin-6-sulfatoxymelatonin-and-sleep-dynamics
#7
Romesh G Abeysuriya, Steven W Lockley, Peter A Robinson, Svetlana Postnova
A biophysical model of the key aspects of melatonin synthesis and excretion has been developed, which is able to predict experimental dynamics of melatonin in plasma and saliva, and of its urinary metabolite 6-sulfatoxymelatonin (aMT6s). This new model is coupled to an established model of arousal dynamics, which predicts sleep and circadian dynamics based on light exposure and times of wakefulness. The combined model thus predicts melatonin levels over the sleep-wake/dark-light cycle and enables prediction of melatonin-based circadian phase markers, such as dim light melatonin onset (DLMO) and aMT6s acrophase under conditions of normal sleep and circadian misalignment...
May 2018: Journal of Pineal Research
https://www.readbyqxmd.com/read/29386442/-hygiene-in-sleep-problems-of-sleeping-habits-in-shift-workers
#8
REVIEW
Masumi Takada
Since World War II, Japan has achieved remarkable economic development and has become an advanced country. Particularly in the industrial field, a production system has been developed to reduce the loss of machining time by adopting a shiftwork in factories operating 24 hours a day, which contributes to the improvement of productivity. Nowadays, this shiftwork practice has spread from the industrial field to other businesses such as 24-hour entertainment facilities and convenience stores, which lead to sleep deprivation in Japanese society...
2018: Nihon Eiseigaku Zasshi. Japanese Journal of Hygiene
https://www.readbyqxmd.com/read/29250769/a-prospective-investigation-of-perceived-stress-infertility-related-stress-and-cortisol-levels-in-women-undergoing-in-vitro-fertilization-influence-on-embryo-quality-and-clinical-pregnancy-rate
#9
Carolyn E Cesta, Anna L V Johansson, Julius Hreinsson, Kenny A Rodriguez-Wallberg, Jan I Olofsson, Jan Holte, Håkan Wramsby, Margareta Wramsby, Sven Cnattingius, Alkistis Skalkidou, Anastasia Nyman Iliadou
INTRODUCTION: Women undergoing fertility treatment experience high levels of stress. However, it remains uncertain if and how stress influences in vitro fertilization (IVF) cycle outcome. This study aimed to investigate whether self-reported perceived and infertility-related stress and cortisol levels were associated with IVF cycle outcomes. MATERIAL AND METHODS: A prospective cohort of 485 women receiving fertility treatment was recruited from September 2011 to December 2013 and followed until December 2014...
March 2018: Acta Obstetricia et Gynecologica Scandinavica
https://www.readbyqxmd.com/read/29211507/association-of-shiftwork-and-leukocytes-among-national-health-and-nutrition-examination-survey-respondents
#10
Megan R Buss, Michael D Wirth, James B Burch
Shift workers may experience disrupted sleep-wake or circadian cycles which, in turn, may lead to major health problems such as hypertension, obesity, and diabetes. Research indicates that shift workers have increased levels of leukocytes. Data from the National Health and Nutrition Examination Survey (2005-2010) examined the relationship between self-reported current shiftwork and leukocytes with adjustment for important confounders. Using linear regression, we found no association between shiftwork and leukocyte counts...
December 6, 2017: Chronobiology International
https://www.readbyqxmd.com/read/29097992/circadian-and-metabolic-effects-of-light-implications-in-weight-homeostasis-and-health
#11
REVIEW
Santiago A Plano, Leandro P Casiraghi, Paula García Moro, Natalia Paladino, Diego A Golombek, Juan J Chiesa
Daily interactions between the hypothalamic circadian clock at the suprachiasmatic nucleus (SCN) and peripheral circadian oscillators regulate physiology and metabolism to set temporal variations in homeostatic regulation. Phase coherence of these circadian oscillators is achieved by the entrainment of the SCN to the environmental 24-h light:dark (LD) cycle, coupled through downstream neural, neuroendocrine, and autonomic outputs. The SCN coordinate activity and feeding rhythms, thus setting the timing of food intake, energy expenditure, thermogenesis, and active and basal metabolism...
2017: Frontiers in Neurology
https://www.readbyqxmd.com/read/29063262/-neurointensive-care-in-germany-results-of-an-inspection-of-intensive-care-units
#12
O Busse, S Hillmann, M Grond
BACKGROUND: The situation of neurointensive care in Germany is unclear. OBJECTIVES: An inspection of neurointensive wards should help to clarify the situation. MATERIALS AND METHODS: On the occasion of stroke unit certification audits, 320 intensive care units (39 independent neurological and 20 neurosurgical, 6 combined neurological/neurosurgical, 253 interdisciplinary intensive wards) were inspected. RESULTS: On the 39 neurological and the 20 neurosurgical intensive care units, a physician with intensive care specialization was available in 92% and 100% of units, respectively, and a physician with authorization for intensive care training was available in 74% and 80% of units, respectively...
February 2018: Der Nervenarzt
https://www.readbyqxmd.com/read/29059251/advancing-the-sleep-wake-schedule-impacts-the-sleep-of-african-americans-more-than-european-americans
#13
Gemma M Paech, Stephanie J Crowley, Louis F Fogg, Charmane I Eastman
There are differences in sleep duration between Blacks/African-Americans and Whites/European-Americans. Recently, we found differences between these ancestry groups in the circadian system, such as circadian period and the magnitude of phase shifts. Here we document the role of ancestry on sleep and cognitive performance before and after a 9-h advance in the sleep/wake schedule similar to flying east or having a large advance in sleep times due to shiftwork, both of which produce extreme circadian misalignment...
2017: PloS One
https://www.readbyqxmd.com/read/29043087/sleepiness-while-driving-and-shiftwork-patterns-among-korean-bus-drivers
#14
Seyoung Lee, Hyoung-Ryoul Kim, Junsu Byun, Taewon Jang
BACKGROUND: Sleepiness while driving has been regarded as a major cause of death due to traffic accidents. We compared the degree of sleepiness across five different working time periods (first, morning, post-lunch, afternoon, and last) among Korean bus drivers with different shift types (Daily two shift/Alternating day shift). METHOD: We interviewed 332 bus drivers with two shift types (Daily two shift, 128; Alternating day shift, 204). The questionnaire included demographic information (age, alcohol consumption and history of disease), a sleep disorder diagnosed by a doctor, job duration, the number of workdays in the past month, average working hours per workday and week, sleepiness while driving (Karolinska Sleepiness Scale), and sleeping time for both workdays and off-days...
2017: Annals of Occupational and Environmental Medicine
https://www.readbyqxmd.com/read/29018021/short-sleep-duration-obstructive-sleep-apnea-shiftwork-and-the-risk-of-adverse-cardiovascular-events-in-patients-after-an-acute-coronary-syndrome
#15
Laura K Barger, Shantha M W Rajaratnam, Christopher P Cannon, Mary Ann Lukas, KyungAh Im, Erica L Goodrich, Charles A Czeisler, Michelle L O'Donoghue
BACKGROUND: It is unknown whether short sleep duration, obstructive sleep apnea, and overnight shift work are associated with the risk of recurrent cardiovascular events in patients after an acute coronary syndrome. METHODS AND RESULTS: SOLID-TIMI 52 (The Stabilization of PLaques UsIng Darapladib-Thrombolysis in Myocardial Infarction 52 Trial) was a multinational, double-blind, placebo-controlled trial that enrolled 13 026 patients ≤30 days of acute coronary syndrome...
October 10, 2017: Journal of the American Heart Association
https://www.readbyqxmd.com/read/28968186/development-and-therapeutic-potential-of-small-molecule-modulators-of-circadian-systems
#16
Zheng Chen, Seung-Hee Yoo, Joseph S Takahashi
Circadian timekeeping systems drive oscillatory gene expression to regulate essential cellular and physiological processes. When the systems are perturbed, pathological consequences ensue and disease risks rise. A growing number of small-molecule modulators have been reported to target circadian systems. Such small molecules, identified via high-throughput screening or derivatized from known scaffolds, have shown promise as drug candidates to improve biological timing and physiological outputs in disease models...
January 6, 2018: Annual Review of Pharmacology and Toxicology
https://www.readbyqxmd.com/read/28933565/sleep-duration-nightshift-work-and-the-timing-of-meals-and-urinary-levels-of-8-isoprostane-and-6-sulfatoxymelatonin-in-japanese-women
#17
Chisato Nagata, Takashi Tamura, Keiko Wada, Kie Konishi, Yuko Goto, Yasuko Nagao, Kazuhiro Ishihara, Satoru Yamamoto
It has been hypothesized that disruption of circadian rhythms affects human health. Shift work and sleep deprivation are thought to disrupt the normal light-dark cycle, although the disruption due to shiftwork may be dependent on sleep deprivation. Both conditions have been suggested to be associated with an increased risk of cardiometabolic disorders. Non-photic environmental factors, such as the timing of eating, are also thought to regulate circadian rhythm and thus, may have effects on health, but the evidence from human studies is scarce...
2017: Chronobiology International
https://www.readbyqxmd.com/read/28912826/can-yesterday-s-smoking-research-inform-today-s-shiftwork-research-epistemological-consequences-for-exposures-and-doses-due-to-circadian-disruption-at-and-off-work
#18
Thomas C Erren, Philip Lewis
In 1950, landmark epidemiology studies by Wynder & Graham and Doll & Hill contributed to identifying smoking as a potent carcinogen. In 2007, IARC classified shiftwork involving circadian disruption (CD) as probably carcinogenic; however, epidemiological evidence in regards to the carcinogenicity of shiftwork that involves nightwork is conflicting. We hypothesize that shiftwork research is lacking chronobiological and methodological rigor and that lessons can be learned from comparison with smoking research...
2017: Journal of Occupational Medicine and Toxicology
https://www.readbyqxmd.com/read/28820862/shiftwork-and-the-retinal-vasculature-diameters-among-police-officers
#19
Luenda E Charles, Ja K Gu, Claudia C Ma, Lisa M Grady, Anna Mnatsakanova, Michael E Andrew, Desta Fekedulegn, John M Violanti, Ronald Klein
OBJECTIVE: To investigate associations of central retinal arteriolar equivalent (CRAE), a measure of retinal arteriolar width, and central retinal venular equivalents (CRVE), a measure of retinal venular width, with shiftwork in 199 police officers (72.9% men). METHODS: Shiftwork (day, afternoon, night) was assessed using electronic payroll records. Four digital retinal images per officer were taken. Mean diameters of the retinal vasculature were compared across shifts using analysis of variance (ANOVA)/analysis of covariance (ANCOVA)...
October 2017: Journal of Occupational and Environmental Medicine
https://www.readbyqxmd.com/read/28709906/effects-of-feeding-time-on-daily-rhythms-of-neuropeptide-and-clock-gene-expression-in-the-rat-hypothalamus
#20
Dawei Wang, Anne-Loes Opperhuizen, Jane Reznick, Nigel Turner, Yan Su, Gregory J Cooney, Andries Kalsbeek
Shiftworkers are exposed to several adverse health conditions, one being eating at night. Food consumption at an unnatural time-of-day is thought to be one of the main factors responsible for the increased risk of developing metabolic diseases, such as obesity and diabetes mellitus. The underlying mechanism is considered to include disruption of the circadian organization of physiology, leading to disruption of metabolism. When food is consumed at night, the hypothalamus, a brain region central to homeostasis, receives contradicting input from the central clock and the systemic circulation...
July 11, 2017: Brain Research
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