keyword
https://read.qxmd.com/read/38535061/thoracic-biometry-in-patients-with-congenital-diaphragmatic-hernia-a-magnetic-resonance-imaging-study
#1
JOURNAL ARTICLE
Erick George Neștianu, Septimiu Popescu, Dragoș Ovidiu Alexandru, Laura Giurcăneanu, Radu Vlădăreanu
This is a retrospective study investigating biometric measurements using magnetic resonance imaging (MRI) examinations in congenital diaphragmatic hernia (CDH). CDH is one of the more common causes of pulmonary hypoplasia, with grave consequences for the fetus. Inclusion criteria were patients diagnosed with CDH as the only observed anomaly, who underwent MRI examination after the second-trimester morphology ultrasound. The patients came from three university hospitals in Bucharest, Romania. In total, 19 patients were included in the study after applying exclusion criteria...
March 18, 2024: Diagnostics
https://read.qxmd.com/read/38533922/a-critical-understanding-of-inclusion-in-oral-microbiome-research-through-the-lens-of-racial-capitalism
#2
JOURNAL ARTICLE
R Lala
There are important calls for greater inclusion of Indigenous and racialised communities in oral microbiome research. This paper uses the concept of racial capitalism (the extractive continuity of colonialism) to critically examine this inclusion agenda. Racial capitalism explicitly links capitalist exploitations with wider social oppressions e.g., racisms, sexism, ableism. It is not confined to the commercial sector but pervades white institutions, including universities. By using the lens of racial capitalism, we find inclusion agendas allow white institutions to extract social and economic value from relations of race...
February 29, 2024: Community Dental Health
https://read.qxmd.com/read/38533921/editorial-oral-health-luxury-or-a-fundamental-human-right-the-necessity-of-introducing-a-dedicated-oral-health-budget-and-proportionate-universalis-in-greece
#3
JOURNAL ARTICLE
A I Syngelakis, M Tsantidou, Z Tsarnava, C Charalambous
Oral health is an integral part of overall health and critically affects quality of life as well as personal and social well-being. Poor oral health negatively influences general health and creates medical, financial and social burdens for individuals, families and health systems. The US Office of Disease Prevention and Health Promotion (2021) sees use of the oral health care system as a leading health indicator. Oral health improvement is an important step to reduce socioeconomic inequalities and promote the UN Sustainable Development Strategy (Wang et al...
February 29, 2024: Community Dental Health
https://read.qxmd.com/read/38532942/role-of-practice-standardization-in-outcome-optimization-for-cdh
#4
REVIEW
Alexandra Dimmer, Robert Baird, Pramod Puligandla
Standardization of care seeks to improve patient outcomes and healthcare delivery by reducing unwanted variations in care as well as promoting the efficient and effective use of healthcare resources. There are many types of standardization, with clinical practice guidelines (CPGs), based on a stringent assessment of evidence and expert consensus, being the hallmark of high-quality care. This article outlines the history of CPGs, their benefits and shortcomings, with a specific focus on standardization efforts as it relates to congenital diaphragmatic hernia management...
2024: World journal of pediatric surgery
https://read.qxmd.com/read/38531327/delivery-room-resuscitation-of-infants-with-congenital-diaphragmatic-hernia-lessons-learned-through-video-review
#5
JOURNAL ARTICLE
K Taylor Wild, Natalie Rintoul, Holly L Hedrick, Lauren Heimall, Leane Soorikian, Elizabeth E Foglia, Anne M Ades, Heidi M Herrick
INTRODUCTION: Delivery room (DR) interventions for infants with congenital diaphragmatic hernia (CDH) are not well described. This study sought to describe timing and order of DR interventions and identify system factors impacting CDH DR resuscitations using a human factors framework. METHODS: Single center observational study of video recorded CDH DR resuscitations documenting timing and order of interventions. The team used the Systems Engineering Initiative for Patient Safety (SEIPS) model to identify system factors impacting DR resuscitations and time to invasive ventilation...
March 26, 2024: Fetal Diagnosis and Therapy
https://read.qxmd.com/read/38524156/bioclonebot-a-versatile-low-cost-and-open-source-automated-liquid-handler
#6
JOURNAL ARTICLE
Ke'Koa Cdh Wells, Nawwaf Kharma, Brandon B Jaunky, Kaiyu Nie, Gabriel Aguiar-Tawil, Daniel Berry
Liquid handler systems can provide significant benefits to researchers by automating laboratory work, however, their unaffordable price provides a steep barrier to entry. Therefore, we provide the BioCloneBot, a versatile, low-cost, and open-source automated liquid handler. This system can be easily built with 3D-printed parts and readily available commercial components. The BioCloneBot is highly adaptive to user needs and facilitates various liquid handling tasks in research and diagnostics. Its user-friendly interface and programmable nature make it suitable for a wide range of applications, from small-scale experiments to larger laboratory setups...
June 2024: HardwareX
https://read.qxmd.com/read/38519389/antenatal-administration-of-extracellular-vesicles-derived-from-amniotic-fluid-stem-cells-improves-lung-function-in-neonatal-rats-with-congenital-diaphragmatic-hernia
#7
JOURNAL ARTICLE
Rebeca L Figueira, Naghmeh Khoshgoo, Fabian Doktor, Kasra Khalaj, Tasneem Islam, Nazgol Moheimani, Matisse Blundell, Lina Antounians, Martin Post, Augusto Zani
BACKGROUND: The severity of pulmonary hypoplasia is a main determinant of outcome for babies with congenital diaphragmatic hernia (CDH). Antenatal administration of extracellular vesicles derived from amniotic fluid stem cells (AFSC-EVs) has been shown to rescue morphological features of lung development in the rat nitrofen model of CDH. Herein, we evaluated whether AFSC-EV administration to fetal rats with CDH is associated with neonatal improvement in lung function. METHODS: AFSC-EVs were isolated by ultracentrifugation and characterized by size, morphology, and canonical marker expression...
February 28, 2024: Journal of Pediatric Surgery
https://read.qxmd.com/read/38518042/unmasking-a-hidden-culprit-late-presenting-congenital-diaphragmatic-hernia-beyond-infancy-a-case-report-and-literature-review
#8
JOURNAL ARTICLE
Wen-Harn Koh, Po-Jui Ko, Yu-Tsun Su, Yu-Cheng Tsai, Ho-Poh Kek, Ching-Chung Tsai
BACKGROUND: Congenital diaphragmatic hernia (CDH) is a rare congenital anomaly with abnormal diaphragm development, typically diagnosed prenatally or soon after birth. Late-presenting CDH presents diagnostic challenges due to nonspecific symptoms that can lead to misdiagnoses. METHODS: This report discusses a 35-month-old female initially presenting with predominant gastrointestinal symptoms and minimal respiratory distress. Initial radiographic findings suggested a left tension pneumothorax, prompting further investigation...
March 22, 2024: Medicine (Baltimore)
https://read.qxmd.com/read/38512194/first-report-of-anthracnose-caused-by-colletotrichum-siamense-on-machilus-thunbergii-siebold-zucc-in-south-korea
#9
JOURNAL ARTICLE
Sung-Eun Cho, Yong-Ho Kim, A-Yeong Heo, Keumchul Shin, Sang-Tae Seo, Heonil Kang, Dong-Hyeon Lee
Machilus thunbergii Siebold & Zucc., known as Japanese bay tree, is an evergreen tree distributed widely in East Asia, including South Korea, where the species is of ecological importance. Machilus thunbergii provides habitat for wildlife species and is a common urban tree. In September 2022, anthracnose symptoms on leaves were observed in Jeju (33°26'02.4"N, 126°19'48.8"E) and Tongyeong (34°49'27.1"N, 128°24'01.8"E) in South Korea. Disease incidence on leaves of each affected tree, naturally growing in an urban forest area covering approximately 0...
March 21, 2024: Plant Disease
https://read.qxmd.com/read/38509614/multicentre-randomised-controlled-trial-of-physiological-based-cord-clamping-versus-immediate-cord-clamping-in-infants-with-a-congenital-diaphragmatic-hernia-pinc-statistical-analysis-plan
#10
RANDOMIZED CONTROLLED TRIAL
Emily J J Horn-Oudshoorn, Marijn J Vermeulen, Ronny Knol, Rebekka Bout-Rebel, Arjan B Te Pas, Stuart B Hooper, Suzan C M Cochius-den Otter, Rene M H Wijnen, Kelly J Crossley, Neysan Rafat, Thomas Schaible, Willem P de Boode, Anne Debeer, Berndt Urlesberger, Calum T Roberts, Florian Kipfmueller, Irma Capolupo, Carmen M Burgos, Bettina E Hansen, Irwin K M Reiss, Philip L J DeKoninck
BACKGROUND: Infants born with congenital diaphragmatic hernia (CDH) are at high risk of respiratory insufficiency and pulmonary hypertension. Routine practice includes immediate clamping of the umbilical cord and endotracheal intubation. Experimental animal studies suggest that clamping the umbilical cord guided by physiological changes and after the lungs have been aerated, named physiological-based cord clamping (PBCC), could enhance the fetal-to-neonatal transition in CDH. We describe the statistical analysis plan for the clinical trial evaluating the effects of PBCC versus immediate cord clamping on pulmonary hypertension in infants with CDH (PinC trial)...
March 20, 2024: Trials
https://read.qxmd.com/read/38500943/survival-and-predictors-of-mortality-of-congenital-diaphragmatic-hernia-in-newborns-at-a-tertiary-care-hospital-in-saudi-arabia
#11
JOURNAL ARTICLE
Khalid Al-Shareef, Mohammed Bhader, Mohammed Alhindi, Khalid Helmi, Salman Ashour, Ahmed Moustafa, Abdullah Al-Harbi, Amir Abushouk, Mansour A AlQurashi
Background Congenital diaphragmatic hernia (CDH) is a condition where abdominal contents protrude into the chest due to defects in the diaphragm muscle. It is considered an emergency that needs urgent intervention to prevent further complications or death. Our study aimed to estimate survival and evaluate predictors of mortality in newborns with CDH using available prediction tools in the literature. Methods This retrospective cohort study included neonates with CDH in King Abdulaziz Medical City (KAMC), Jeddah, from 2000 to 2021...
February 2024: Curēus
https://read.qxmd.com/read/38498203/pulmonary-vasculature-development-in-congenital-diaphragmatic-hernia-a-novel-automated-quantitative-imaging-analysis
#12
JOURNAL ARTICLE
Emrah Aydın, Furkan Durmuş, Nilhan Torlak, Marc Oria, Nilgün Güler Bayazıt, Esin Öztürk Işık, Birol Aslanyürek, Jose L Peiro
PURPOSE: Impaired fetal lung vasculature determines the degree of pulmonary hypertension in the congenital diaphragmatic hernia (CDH). This study aims to demonstrate the morphometric measurements that differ in pulmonary vessels of fetuses with CDH. METHODS: Nitrofen-induced CDH Sprague-Dawley rat fetuses were scanned with microcomputed tomography. The analysis of the pulmonary vascular tree was performed with artificial intelligence. RESULTS: The number of segments in CDH was significantly lower than that in the control group on the left (U = 2...
March 18, 2024: Pediatric Surgery International
https://read.qxmd.com/read/38492743/-antenatal-care-for-fetuses-with-congenital-diaphragmatic-hernia
#13
JOURNAL ARTICLE
Charles Mégier, Alexandra Letourneau, Lina Bejjani, Meriem Macha Boumerzoug, Cécile Suffee, Van Huynh, Julien Saada, Grégoire Dumery, Alexandra Benachi
Congenital diaphragmatic hernia (CDH) can be diagnosed prenatally and its severity assessed by fetal imaging. The prognosis of a fetus with CDH is based on whether or not the hernia is isolated, the measurement of lung volume on ultrasound and MRI, and the position of the liver. The birth of a child with CDH should take place in a center adapted to the care of such children, and in accordance with the recommendations defined by the French National Diagnosis and Care Protocol. It has recently been demonstrated that for moderate and severe forms of CDH, tracheal occlusion using a balloon placed in utero by fetoscopy (FETO) increases survival until discharge from the neonatal unit, but at the cost of an increased risk of prematurity...
March 14, 2024: Gynecologie, Obstetrique, Fertilite & Senologie
https://read.qxmd.com/read/38472353/the-rna-binding-protein-quaking-is-upregulated-in-nitrofen-induced-congenital-diaphragmatic-hernia-lungs-at-the-end-of-gestation
#14
JOURNAL ARTICLE
Yuichiro Miyake, Dustin Ameis, Wai Hei Tse, Daywin Patel, Arzu Ozturk Aptekmann, Atsuyuki Yamataka, Richard Keijzer
BACKGROUND: The RNA-binding protein Quaking (QKI) increases during epithelial-to-mesenchymal transition and its expression is controlled by microRNA-200 family members. Here, we aimed to describe the expression of QKI in the developing lungs of control and nitrofen-induced congenital diaphragmatic hernia lungs (CDH). METHODS: To investigate the expression of QKI, we dissected lungs from control and nitrofen-induced CDH rats on embryonic day 15, 18, 21 (E15, E18, E21)...
March 13, 2024: Pediatric Surgery International
https://read.qxmd.com/read/38454966/3d-printing-sequentially-strengthening-high-strength-natural-polymer-hydrogel-bilayer-scaffold-for-cornea-regeneration
#15
JOURNAL ARTICLE
Xiongfeng Nie, Yong Tang, Tengling Wu, Xinrui Zhao, Ziyang Xu, Rong Yang, Yage Sun, Bin Wu, Quanhong Han, Jingwen Hui, Wenguang Liu
3D printing of high-strength natural polymer biodegradable hydrogel scaffolds simultaneously resembling the biomechanics of corneal tissue and facilitating tissue regeneration remains a huge challenge due to the inherent brittleness of natural polymer hydrogels and the demanding requirements of printing. Herein, concentrated aqueous solutions of gelatin and carbohydrazide-modified alginate (Gel/Alg-CDH) are blended to form a natural polymer hydrogel ink, where the hydrazides in Alg-CDH are found to form strong hydrogen bonds with the gelatin...
2024: Regenerative Biomaterials
https://read.qxmd.com/read/38451374/evaluation-of-the-effect-of-cervical-and-lumbar-disc-herniations-on-female-sexual-function-a-comparative-prospective-study
#16
JOURNAL ARTICLE
Sameh Fayek GamalEl Din, Nashaat Nabil, Mohamed Alaa, Mohamed Ahmed Abdel Salam, Ahmed Raef, Rana Barakat Elhalaly, Ahmed Abo Sief
PURPOSE: We aimed to evaluate the effect of cervical disc herniation (CDH) and lumbar disc herniation (LDH) on female sexual functioning before and after surgical intervention. METHODS: The current study was conducted from February 2022 to February 2023. A total of 100 sexually active female patients in their reproductive phase who were diagnosed with CDH and LDH based on physical examination and previous magnetic resonance imaging (MRI) results, as well as 50 healthy females, were enrolled...
March 7, 2024: European Spine Journal
https://read.qxmd.com/read/38450531/patches-in-congenital-diaphragmatic-hernia-a-systematic-review
#17
JOURNAL ARTICLE
Amulya K Saxena, Romilly K Hayward
OBJECTIVE: This systematic review aims to evaluate current choice in practice and outcomes of biomaterials used in patch repair of congenital diaphragmatic hernia (CDH). BACKGROUND: Multiple biomaterials, both novel and combinations of pre-existing materials are employed in patch repair of large size CDH. METHODS: Literature search was performed across Embase, Medline, Scopus, and Web of Science. Publications that explicitly reported patch repair, material used and recurrences following CDH repair were selected...
March 7, 2024: Annals of Surgery
https://read.qxmd.com/read/38440902/relative-mediastinal-displacement-index-rmdi-a-prenatal-mri-indicator-of-adverse-events-in-fetuses-with-isolated-left-congenital-diaphragmatic-hernia
#18
JOURNAL ARTICLE
Fan Wu, Yonghao Chen, Xin Zhang, Yuchao Li, Zhaoji Chen, Zhenqing Liu, Wangchun Dai, Chaoxiang Yang, Hongsheng Liu
BACKGROUND: Extracorporeal membrane oxygenation (ECMO), has partly improved congenital diaphragmatic hernia (CDH) outcomes, yet the overall morbidity and mortality remain high. Existing prenatal indicators for CDH fetuses are operator-dependent, time-consuming, or less accurate, a new simple and accurate indicator to indicate adverse events in CDH patients is needed. PURPOSE: To propose and assess the association of a new MRI parameter, the relative mediastinal displacement index (RMDI), with adverse events including in-hospital deaths or the need for ECMO in fetuses with isolated left CDH (iLCDH)...
March 5, 2024: Journal of Magnetic Resonance Imaging: JMRI
https://read.qxmd.com/read/38438690/the-association-of-prenatal-diagnoses-with-mortality-and-long-term-morbidity-in-children-with-specific-isolated-congenital-anomalies-a-european-register-based-cohort-study
#19
JOURNAL ARTICLE
Anna Heino, Joan K Morris, Ester Garne, Silvia Baldacci, Ingeborg Barisic, Clara Cavero-Carbonell, Laura García-Villodre, Joanne Given, Sue Jordan, Maria Loane, L Renée Lutke, Amanda J Neville, Michele Santoro, Ieuan Scanlon, Joachim Tan, Hermien E K de Walle, Sonja Kiuru-Kuhlefelt, Mika Gissler
OBJECTIVES: To compare 5-year survival rate and morbidity in children with spina bifida, transposition of great arteries (TGA), congenital diaphragmatic hernia (CDH) or gastroschisis diagnosed prenatally with those diagnosed postnatally. METHODS: Population-based registers' data were linked to hospital and mortality databases. RESULTS: Children whose anomaly was diagnosed prenatally (n = 1088) had a lower mean gestational age than those diagnosed postnatally (n = 1698) ranging from 8 days for CDH to 4 days for TGA...
March 4, 2024: Maternal and Child Health Journal
https://read.qxmd.com/read/38432836/reliability-of-ultrasonography-to-measure-cervical-multifidus-semispinalis-cervicis-and-longus-colli-muscles-dimensions-in-patients-with-unilateral-cervical-disc-herniation-an-observational-cross-sectional-test-retest-study
#20
JOURNAL ARTICLE
Fariba Mohseni, Nahid Rahmani, Mohammad Ali Mohseni Bandpei, Iraj Abdollahi
BACKGROUND: Ultrasonography (US) has been suggested to assess the morphology and function of cervical muscles; but little is known about the reliability of the US measures in patients with cervical disc herniation (CDH). The purpose of this study was to evaluate within-day inter and intra-rater and between-day intra-rater reliability of US to measure dimensions of deep cervical muscles in patients with unilateral CDH. METHODS: Thirty patients with unilateral CDH participated...
January 2024: Journal of Bodywork and Movement Therapies
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