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https://www.readbyqxmd.com/read/28527341/unravelling-respiratory-syncytial-virus-outbreaks-in-buenos-aires-argentina-molecular-basis-of-the-spatio-temporal-transmission
#1
Gabriel Lihue Rojo, Stephanie Goya, Mariana Orellana, Andrea Sancilio, Alberto Rodriguez Perez, César Montali, Carolina García, Lilian Sosa, Alejandra Musto, Daniela Alvarez, Alejandro Castello, Mariana Viegas
Respiratory syncytial virus (RSV) is the main viral cause of hospitalization due to acute lower respiratory tract infections in infants worldwide. Several vaccines against RSV are under research and development, which are about to be approved. We evaluated transmission patterns in different settings to determine age-specific vaccination targets from a viral perspective. We sequenced the G glycoprotein's ectodomain of a constant clinical sampling between two epidemic outbreaks in a limited geographical region and performed phylogeographic analyses...
May 17, 2017: Virology
https://www.readbyqxmd.com/read/28526663/effects-of-using-child-personas-in-the-development-of-a-digital-peer-support-service-for-childhood-cancer-survivors
#2
Pontus Wärnestål, Petra Svedberg, Susanne Lindberg, Jens M Nygren
BACKGROUND: Peer support services have the potential to support children who survive cancer by handling the physical, mental, and social challenges associated with survival and return to everyday life. Involving the children themselves in the design process allows for adapting services to authentic user behaviors and goals. As there are several challenges that put critical requirements on a user-centered design process, we developed a design method based on personas adapted to the particular needs of children that promotes health and handles a sensitive design context...
May 18, 2017: Journal of Medical Internet Research
https://www.readbyqxmd.com/read/28526638/prevalence-and-antimicrobial-susceptibility-of-salmonella-and-shigella-spp-among-children-with-gastroenteritis-in-an-iranian-referral-hospital
#3
Shima Mahmoudi, Babak Pourakbari, Mina Moradzadeh, Hamid Eshaghi, Amitis Ramezani, Mohammad Taghi Haghi Ashtiani, Sepideh Keshavarz Valian, Setareh Mamishi
BACKGROUND: Gastroenteritis is one of the leading cause of illnesses through the world, especially in developing countries.Salmonella and Shigella infections are considered as the main public health problems in children. The aim of this study was to detect the prevalence and antimicrobial susceptibility of Salmonella and Shigella spp. among children with gastroenteritis in an Iranian referral hospital. METHODS: During April 2013 to April 2014, all medical records of children with gastroenteritis admitted to a pediatric medical center were evaluated...
May 16, 2017: Microbial Pathogenesis
https://www.readbyqxmd.com/read/28526064/seasonal-variation-in-the-prevalence-of-toxocara-eggs-on-children-s-playgrounds-in-the-city-of-hanover-germany
#4
Annika Kleine, Andrea Springer, Christina Strube
BACKGROUND: Roundworms of the genus Toxocara are worldwide distributed zoonotic parasites of carnivores. Based on case numbers and the potential impact on human health, the Centers for Disease Control and Prevention (CDC) categorised toxocarosis as one of the most important neglected parasitic diseases. As contact with contaminated soil, e.g. in sandpits, is considered the primary transmission route, data on playground contamination are needed to assess infection risk for children. Here, playground contamination rates and their seasonal variation in the city of Hanover, Germany, were investigated...
May 19, 2017: Parasites & Vectors
https://www.readbyqxmd.com/read/28526006/cardiometabolic-profile-of-obese-children-in-a-sub-saharan-african-setting-a-cross-sectional-study
#5
Eunice Chedjou-Nono, Suzanne Sap, Simeon-Pierre Choukem, Issa Ngosso Tetanye, Daniel Nebongo, Olivier Koki Ndombo
BACKGROUND: Cardiovascular and metabolic consequences of obesity in children, unlike adults, are still not well understood nor have they been subject to extensive research in Africa. We aimed to identify the cardio-metabolic complications associated with childhood obesity at the early phase of the management of obese children in a reference center in Cameroon. METHODS: In this cross-sectional study conducted from November 2013 to September 2014 and based on World Health Organization (WHO) classification of Obesity (BMI > 3SD under 5 years and BMI > 2SD from 5 and above), we included children aged 3 to 17 years who were being followed up for obesity at the pediatric endocrinology unit of the Mother and Child Center of the Chantal BIYA Foundation in Yaounde, Cameroon...
May 19, 2017: BMC Pediatrics
https://www.readbyqxmd.com/read/28524702/school-success-and-participation-for-students-with-cerebral-palsy-a-qualitative-study-exploring-multiple-perspectives
#6
Helen M Bourke-Taylor, Claire Cotter, Aislinn Lalor, Lindy Johnson
PURPOSE: This qualitative study investigated perceived successful school experiences for students with cerebral palsy in Australia. Participation and appropriate support in school are complex concepts, although few studies have investigated all stakeholders' perspectives. METHODS: Phenomenology informed the study that centered on the concept of a successful school experience. In-depth interviews occurred with students (n = 7), parents (n = 11), teachers (n = 10), school principals (n = 9) and allied health practitioners (n = 10) to gain the perspective from multiple vantage points...
May 19, 2017: Disability and Rehabilitation
https://www.readbyqxmd.com/read/28520816/high-prevalence-of-elevated-blood-lead-levels-in-both-rural-and-urban-iowa-newborns-spatial-patterns-and-area-level-covariates
#7
Margaret Carrel, David Zahrieh, Sean G Young, Jacob Oleson, Kelli K Ryckman, Brian Wels, Donald L Simmons, Audrey Saftlas
Lead in maternal blood can cross the placenta and result in elevated blood lead levels in newborns, potentially producing negative effects on neurocognitive function, particularly if combined with childhood lead exposure. Little research exists, however, into the burden of elevated blood lead levels in newborns, or the places and populations in which elevated lead levels are observed in newborns, particularly in rural settings. Using ~2300 dried bloods spots collected within 1-3 days of birth among Iowa newborns, linked with the area of mother's residence at the time of birth, we examine the spatial patterns of elevated (>5 μg/dL) blood lead levels and the ecological-level predictors of elevated blood lead levels...
2017: PloS One
https://www.readbyqxmd.com/read/28514463/pediatric-psoriasis-comorbidity-screening-guidelines
#8
Emily Osier, Audrey S Wang, Megha M Tollefson, Kelly M Cordoro, Stephen R Daniels, Andrew Eichenfield, Joel M Gelfand, Alice B Gottlieb, Alexa B Kimball, Mark Lebwohl, Nehal N Mehta, Amy S Paller, Jeffrey B Schwimmer, Dennis M Styne, Abby S Van Voorhees, Wynnis L Tom, Lawrence F Eichenfield
Importance: Psoriasis is a complex inflammatory skin condition associated with serious medical comorbidities in adults, including obesity, hypertension, dyslipidemia, type 2 diabetes mellitus, psoriatic arthritis, nonalcoholic fatty liver disease, depression, anxiety, and decreased quality of life. Because psoriasis begins in childhood in almost one-third of patients, early identification of risk may be critical to minimizing effects on future health. Objective: To develop the first set of guidelines for comorbidity screening for patients with pediatric psoriasis based on current evidence...
May 17, 2017: JAMA Dermatology
https://www.readbyqxmd.com/read/28511778/elevated-cranial-ultrasound-resistive-indices-are-associated-with-improved-neurodevelopmental-outcomes-one-year-after-pediatric-cardiac-surgery-a-single-center-pilot-study
#9
Christopher L Jenks, Ana Hernandez, Peter L Stavinoha, Michael C Morris, Fenghua Tian, Hanli Liu, Parvesh Garg, Joseph M Forbess, Joshua Koch
OBJECTIVE: To determine if a non-invasive, repeatable test can be used to predict neurodevelopmental outcomes in patients with congenital heart disease. METHODS: This was a prospective study of pediatric patients less than two months of age undergoing congenital heart surgery at the Children's Health Children's Medical Center at Dallas. Multichannel near-infrared spectroscopy (NIRS) was utilized during the surgery, and ultrasound (US) resistive indices (RI) of the major cranial vessels were obtained prior to surgery, immediately post-operatively, and prior to discharge...
May 13, 2017: Heart & Lung: the Journal of Critical Care
https://www.readbyqxmd.com/read/28511437/children-s-physical-activity-awareness-among-mothers-in-a-saudi-arabian-health-center
#10
Maysah Amer, Ghada Al Arfaj, Abdulaziz A Alodhayani
INTRODUCTION: Physical inactivity is a major contributor to the increasing levels of obesity and other serious medical conditions among children and adolescents worldwide. A major factor in this increase is lack of awareness of mothers' regarding the Physical Activity (PA) of their children. AIM: The current study aimed to identify the degree of knowledge and awareness of Saudi mothers' regarding their children's physical activities, which will be useful for improving physical education, health programs, and eventually children's health care...
March 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28508700/the-chronicity-of-depressive-symptoms-in-mothers-of-children-with-asthma
#11
Joan Kub, Melissa H Bellin, Arlene Butz, Mary Elizabeth Bollinger, Cassia Lewis-Land, Philip Osteen
Depression can disproportionately affect low-income women. The purpose of this study was to explore the chronicity of depressive symptoms in a sample of 276 low-income inner-city mothers of children with high-risk asthma. The aims were to identify factors (asthma health status, stress, social support) associated with change in depressive symptomatology over 12 months as well as to ascertain what factors are most consistently associated with depressive symptoms. Using latent growth curve analysis, demographic variables, asthma severity, stress, and social support failed to explain changes in depressive symptomatology...
May 1, 2017: Western Journal of Nursing Research
https://www.readbyqxmd.com/read/28507765/asthma-epidemiology-of-disease-control-in-latin-america-short-review
#12
REVIEW
Dirceu Solé, Carolina Sanchez Aranda, Gustavo Falbo Wandalsen
Asthma is reported as one of the most common chronic diseases in childhood, impairing the quality of life of patients and their families and incurring high costs to the healthcare system and society. Despite the development of new drugs and the availability of international treatment guidelines, asthma is still poorly controlled, especially in Latin America. Original and review articles on asthma control or epidemiology with high levels of evidence have been selected for analysis among those published in PubMed referenced journals during the last 20 years, using the following keywords: "asthma control" combined with "Latin America", " epidemiology", "prevalence", "burden", "mortality", "treatment and unmet needs", "children", "adolescents", and "infants"...
2017: Asthma research and practice
https://www.readbyqxmd.com/read/28507158/impact-of-international-monetary-fund-programs-on-child-health
#13
Adel Daoud, Elias Nosrati, Bernhard Reinsberg, Alexander E Kentikelenis, Thomas H Stubbs, Lawrence P King
Parental education is located at the center of global efforts to improve child health. In a developing-country context, the International Monetary Fund (IMF) plays a crucial role in determining how governments allocate scarce resources to education and public health interventions. Under reforms mandated by IMF structural adjustment programs, it may become harder for parents to reap the benefits of their education due to wage contraction, welfare retrenchment, and generalized social insecurity. This study assesses how the protective effect of education changes under IMF programs, and thus how parents' ability to guard their children's health is affected by structural adjustment...
May 15, 2017: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/28506503/extended-clinical-spectrum-of-anti-n-methyl-d-aspartate-receptor-encephalitis-in-children-a-case-series
#14
Ajay Goenka, Vivek Jain, Hiroki Nariai, Alfred Spiro, Mitchell Steinschneider
OBJECTIVE: There is a wide spectrum of clinical manifestations in children with anti-N-methyl-d-aspartate (NMDA) receptor antibody encephalitis from two different health care settings. METHODS: We describe our experience with 13 patients (median age, 7 years; range, 5 months to 19 years) presenting to tertiary referral centers in India and the United States. RESULTS: Initial manifestations were neurological (seizures or movement disorders) in eight patients, and psychiatric (e...
April 5, 2017: Pediatric Neurology
https://www.readbyqxmd.com/read/28505524/inactivated-influenza-virus-vaccines-the-future-of-tiv-and-qiv
#15
REVIEW
Michael Schotsaert, Adolfo García-Sastre
Influenza viruses continue to be a major public health concern, despite the availability of vaccines. Currently licensed influenza vaccines aim at the induction of antibodies that target hemagglutinin, the major antigenic determinant on the surface of influenza virions that is responsible for attachment of the virus to the host cell that is to be infected. Currently licensed influenza vaccines come as inactivated or live attenuated influenza vaccines and are trivalent or quadrivalent as they contain antigens of two influenza A and one or two influenza B strains that circulate in the human population, respectively...
May 12, 2017: Current Opinion in Virology
https://www.readbyqxmd.com/read/28503996/primary-immunization-of-human-papillomavirus-vaccine-in-the-pediatric-population-what-is-the-verdict-now
#16
Aubrey N Jones, Jenna W Bartlett, Rebecca A Bates, Tsz-Yin So
The safety and efficacy of a 2-dose series for the human papillomavirus vaccines rather than a 3-dose series in older children has not been well defined. This article reviews the literature summarizing the use of all 3 HPV vaccines (2vHPV, 4vHPV, 9vHPV) as a 2-dose series for females and 4vHPV and 9vHPV for males younger than 15 years. Six prospective trials evaluating immunogenicity of a 2-dose series of 2vHPV and/or 4vHPV, as well as an ongoing prospective clinical trial for 9vHPV, are discussed. The 2-dose series with Gardasil 9(®) in both males and females ages 9 to 14 years appears to be the most widely accepted recommendation...
June 2017: Clinical Pediatrics
https://www.readbyqxmd.com/read/28498231/metrics-to-assess-extracorporeal-membrane-oxygenation-utilization-in-pediatric-cardiac-surgery-programs
#17
Susan L Bratton, Titus Chan, Cindy S Barrett, Jacob Wilkes, Laura M Ibsen, Ravi R Thiagarajan
OBJECTIVES: Only a small fraction of pediatric cardiac surgical patients are supported with extracorporeal membrane oxygenation following cardiac surgery, but extracorporeal membrane oxygenation use is more common among those undergoing higher complexity surgery. We evaluated extracorporeal membrane oxygenation metrics indexed to annual cardiac surgical volume to better understand extracorporeal membrane oxygenation use among U.S. cardiac surgical programs. DESIGN: Retrospective analysis SETTING:: Forty-three U...
May 11, 2017: Pediatric Critical Care Medicine
https://www.readbyqxmd.com/read/28495041/staff-workshop-improves-child-care-center-menus-in-south-central-texas-a-best-food-for-families-infants-and-toddlers-best-food-fits-intervention
#18
Brittany Reese Markides, Sylvia Hurd Crixell, Courtney Thompson, Lesli Biediger-Friedman
OBJECTIVE: To assess the efficacy of an educational workshop for child care center staff to improve menus. METHODS: Staff from 18 centers attended a nutrition educational workshop that included an activity that compared center menus to MyPlate standards. Four weeks of menus collected before and after the workshop were imported into SuperTracker; the Food Details report produced menu data clustered by day and center. Changes in pre-post menus were assessed using Healthy Eating Index scores and the SAS software macro, MIXCORR...
May 2017: Journal of Nutrition Education and Behavior
https://www.readbyqxmd.com/read/28493608/the-epidemiology-of-emergency-department-trauma-discharges-in-the-united-states
#19
Charles J DiMaggio, Jacob B Avraham, David C Lee, Spiros G Frangos, Stephen P Wall
OBJECTIVE: Injury related morbidity and mortality is an important emergency medicine and public health challenge in the United States (US). Here we describe the epidemiology of traumatic injury presenting to US emergency departments, define changes in types and causes of injury among the elderly and the young, characterize the role of trauma centers and teaching hospitals in providing emergency trauma care, and estimate the overall economic burden of treating such injuries. METHODS: We conducted a secondary retrospective, repeated cross-sectional study of the Nationwide Emergency Department Data Sample (NEDS), the largest all-payer emergency department survey database in the US...
May 11, 2017: Academic Emergency Medicine: Official Journal of the Society for Academic Emergency Medicine
https://www.readbyqxmd.com/read/28492929/hepatitis-c-virus-infection-among-reproductive-aged-women-and-children-in-the-united-states-2006-to-2014
#20
Kathleen N Ly, Ruth B Jiles, Eyasu H Teshale, Monique A Foster, Rick L Pesano, Scott D Holmberg
Background: In the United States, hepatitis C virus (HCV) infection has increased among young persons who inject drugs, but the extent of this epidemic among reproductive-aged women and their children is unknown. Objective: To estimate numbers and describe characteristics of reproductive-aged women with HCV infection and of their offspring. Design: Analysis of the National Notifiable Diseases Surveillance System (NNDSS) from 2006 to 2014 and the Quest Diagnostics Health Trends national database from 2011 to 2014...
May 9, 2017: Annals of Internal Medicine
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