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hanging death

Daniel Schober, Nicole Schwendener, Wolf-Dieter Zech, Christian Jackowski
Segmentation of the lungs using post-mortem computed tomography (PMCT) data was so far not feasible due to post-mortem changes such as internal livores. Recently, an Osirix plug-in has been developed allowing automatically segmenting lungs also in PMCT data. The aim of this study was to investigate if the Hounsfield unit (HU) profiles obtained in PMCT data of the segmented lung tissue present with specific behaviour in relation to the cause of death. In 105 PMCT data sets of forensic cases, the entire lung volumes were segmented using the Mia Lite plug-in on Osirix...
October 20, 2016: International Journal of Legal Medicine
Yin-Jian Yang, Chao-Mei Fan, Jin-Qing Yuan, Hai-Bin Zhang, Fu-Jian Duan, Zhi-Min Wang, Xi-Ying Guo, Shan-Shan Zhai, Shuo-Yan An, Fei Hang, Yi-Shi Li
BACKGROUND: Hypertrophic cardiomyopathy (HCM) is associated with poor prognosis. It has been reported that there is no difference in in-hospital mortality after acute myocardial infarction (AMI) between patients with and without HCM. However, whether there is a difference in long-term survival after AMI between patients with and without HCM remains unclear. HYPOTHESIS: Long-term survival after AMI is worse in patients with vs without HCM. METHODS: The clinical profiles of 91 consecutive patients with HCM and AMI (HCM group) and 91 sex- and age-matched patients with AMI without HCM (non-HCM group) were analyzed...
October 17, 2016: Clinical Cardiology
Ethan C Jamison, Kirk A Bol
INTRODUCTION: Non-fatal suicide attempts are a risk factor for suicide, but less is known about its effect on the method of injury used in an eventual suicide death. This study examines the association between history of non-fatal suicide attempt and the risk of a poisoning suicide versus firearm or hanging suicide in Colorado. METHODS: Nine years (2004-2012, N=7,020) of suicide deaths in Colorado were compiled through the National Violent Death Reporting System...
November 2016: American Journal of Preventive Medicine
Kenan Karbeyaz, Mehmet Toygar, Adnan Çelikel
INTRODUCTION: In this study student suicides are classified as a distinct group in Eskisehir-a city located in the western part of our country and famous as a student city. The study aims at describing demographic and suicide specification of cases and compare some important issues between males and females. METHOD: All the judicially deaths in Eskisehir in a 12 year period between 2004 and 2015 have been evaluated. 75 cases that were deemed as suicide cases as a result of criminal investigation have been included in the study...
September 28, 2016: Journal of Forensic and Legal Medicine
Hang Yao, Priti Azad, Huiwen W Zhao, Juan Wang, Orit Poulsen, Beatriz C Freitas, Alysson R Muotri, Gabriel G Haddad
The sodium bicarbonate co-transporter (NBC) is the major bicarbonate-dependent acid-base transporter in mammalian astrocytes and has been implicated in ischemic brain injury. A malfunction of astrocytes could have great impact on the outcome of stroke due to their participation in the formation of blood-brain barrier, synaptic transmission, and electrolyte balance in the human brain. Nevertheless, the role of NBC in the ischemic astrocyte death has not been well understood. In this work, we obtained skin biopsies from healthy human subjects and had their fibroblasts grown in culture and reprogrammed into human-induced pluripotent stem cells (hiPSCs)...
October 4, 2016: Neuroscience
M Garetier, L Deloire, F Dédouit, E Dumousset, C Saccardy, D Ben Salem
Suicide is the eighth cause of mortality in France and the leading cause in people aged between 25 and 34 years. The most common methods of suicide are hanging, self-poisoning with medicines and firearms. Postmortem computed tomography (CT) is a useful adjunct to autopsy to confirm suicide and exclude other causes of death. At autopsy, fractures of the hyoid bone or thyroid cartilage, or both, are found in more than 50% of suicidal hangings. Cervical vertebra fractures are rare and only seen in suicide victims jumping from a great height...
September 26, 2016: Diagnostic and Interventional Imaging
Yi-Sheng Sun, Ya-Jing Li, Yong Xia, Fang Xu, Wei-Wei Wang, Zhang-Nv Yang, Hang-Jing Lu, Zhi-Ping Chen, Zi-Ping Miao, Wei-Feng Liang, Zhi-Yao Xu, Hong-Jun Dong, Dan-Hong Qiu, Zhi-Yong Zhu, Stijn van der Veen, Jie Qian, Bin Zhou, Ping-Ping Yao, Han-Ping Zhu
Coxsackievirus A16 (CA16) is one of the major pathogens associated with human hand, foot, and mouth disease (HFMD) in the Asia-pacific region. Although CA16 infections are generally mild, severe neurological manifestations or even death has been reported. Studies on CA16 pathogenesis and vaccine development are severely hampered because the small animal models that are currently available show major limitations. In this study, gerbils (Meriones unguiculatus) were investigated for their suitability as an animal model to study CA16 pathogenesis and vaccine development...
September 26, 2016: Scientific Reports
Osvaldo P Almeida, Kieran McCaul, Graeme J Hankey, Bu B Yeap, Jonathan Golledge, Leon Flicker
Suicide rates are high in later life, particularly among older men. Mood disorders are known risk factors, but the risk of suicide associated with poor physical health remains unclear. We completed a cohort study of a community representative sample of 38,170 men aged 65-85 in 1996 who were followed for up to 16years. Data on suicide attempts and completion were obtained from the Western Australia Data Linkage System, as was information about medical and mental health diagnoses. 240 (0.6%) participants had a recorded history of past suicide attempt, most commonly by poisoning (85%)...
September 20, 2016: Preventive Medicine
Arielle H Sheftall, Lindsey Asti, Lisa M Horowitz, Adrienne Felts, Cynthia A Fontanella, John V Campo, Jeffrey A Bridge
BACKGROUND AND OBJECTIVES: Suicide in elementary school-aged children is not well studied, despite a recent increase in the suicide rate among US black children. The objectives of this study were to describe characteristics and precipitating circumstances of suicide in elementary school-aged children relative to early adolescent decedents and identify potential within-group racial differences. METHODS: We analyzed National Violent Death Reporting System (NVDRS) surveillance data capturing suicide deaths from 2003 to 2012 for 17 US states...
September 19, 2016: Pediatrics
Syed Tariq Khalil, Michael R Uhing, Lori Duesing, Alexis Visotcky, Sergey Tarima, T Hang Nghiem-Rao
BACKGROUND: The aim of this study was to determine the tube-related complications and feeding outcomes of infants discharged home from the neonatal intensive care unit (NICU) with nasogastric (NG) tube feeding or gastrostomy (G-tube) feeding. MATERIALS AND METHODS: We performed a chart review of 335 infants discharged from our NICU with home NG tube or G-tube feeding between January 2009 and December 2013. The primary outcome was the incidence of feeding tube-related complications requiring emergency department (ED) visits, hospitalizations, or deaths...
September 19, 2016: JPEN. Journal of Parenteral and Enteral Nutrition
Xiao-Wan Bo, Hui-Xiong Xu, Dan Wang, Le-Hang Guo, Li-Ping Sun, Xiao-Long Li, Chong-Ke Zhao, Ya-Ping He, Bo-Ji Liu, Dan-Dan Li, Kun Zhang
OBJECTIVES: To investigate the usefulness of fusion imaging of contrast-enhanced ultrasound (CEUS) and CECT/or CEMRI before percutaneous ultrasound (US)-guided radiofrequency ablation (RFA) for liver cancers. METHODS: 45 consecutive patients with 70 liver lesions were included between March 2013 and October 2015 and all the lesions were identified on CEMRI/CECT prior to inclusion in the study. Planning US for percutaneous RFA was performed using conventional US, US-CECT/CEMRI and CEUS-CECT/CEMRI fusion imaging respectively during the same session...
September 14, 2016: British Journal of Radiology
Liu-Xin Cai, Fang-Qiang Wei, Yi-Chen Yu, Xiu-Jun Cai
OBJECTIVE: The liver hanging maneuver (LHM) is rarely applied in laparoscopic right hepatectomy (LRH) because of the difficulty encountered in retrohepatic tunnel (RT) dissection and tape positioning. Thus far no report has detailed how to quickly and easily establish RT for laparoscopic LHM in LRH, nor has employment of the Goldfinger dissector to create a total RT been reported. This study's aim was to evaluate the safety and feasibility of establishing RT for laparoscopic LHM using the Goldfinger dissector in LRH...
September 2016: Journal of Zhejiang University. Science. B
Lida Derevnina, Yasin F Dagdas, Juan Carlos De la Concepcion, Aleksandra Bialas, Ronny Kellner, Benjamin Petre, Emmanouil Domazakis, Juan Du, Chih-Hang Wu, Xiao Lin, Carolina Aguilera-Galvez, Neftaly Cruz-Mireles, Vivianne G A A Vleeshouwers, Sophien Kamoun
I. II. III. IV. V. VI. VII. VIII. IX. X. XI. References SUMMARY: Elicitins are structurally conserved extracellular proteins in Phytophthora and Pythium oomycete pathogen species. They were first described in the late 1980s as abundant proteins in Phytophthora culture filtrates that have the capacity to elicit hypersensitive (HR) cell death and disease resistance in tobacco. Later, they became well-established as having features of microbe-associated molecular patterns (MAMPs) and to elicit defences in a variety of plant species...
September 1, 2016: New Phytologist
Haibo Jia, Jiannan Dai, Jingbo Hou, Lei Xing, Lijia Ma, Huimin Liu, Maoen Xu, Yuan Yao, Sining Hu, Erika Yamamoto, Hang Lee, Shaosong Zhang, Bo Yu, Ik-Kyung Jang
AIMS: Plaque erosion, compared with plaque rupture, has distinctly different underlying pathology and therefore may merit tailored therapy. In this study, we aimed to assess whether patients with acute coronary syndrome (ACS) caused by plaque erosion might be stabilized by anti-thrombotic therapy without stent implantation. METHODS AND RESULTS: This was a single-centre, uncontrolled, prospective, proof-of concept study. Patients with ACS including ST-segment elevation myocardial infarction were prospectively enrolled...
August 30, 2016: European Heart Journal
Chunjie Li, Shaomeng Chai, Yongzhi Ju, Lu Hou, Hang Zhao, Wei Ma, Tian Li, Jun Sheng, Wei Shi
Glutamate is one of the major excitatory neurotransmitters of the CNS and is essential for numerous key neuronal functions. However, excess glutamate causes massive neuronal death and brain damage owing to excitotoxicity via the glutamate receptors. Metabotropic glutamate receptor 5 (mGluR5) is one of the glutamate receptors and represents a promising target for studying neuroprotective agents of potential application in neurodegenerative diseases. Pu-erh tea, a fermented tea, mainly produced in Yunnan province, China, has beneficial effects, including the accommodation of the CNS...
August 30, 2016: Molecular Neurobiology
Wei Jia, Wei Wang, Chu-Shu Ji, Jun-Yang Niu, Ya-Jing Lv, Hang-Cheng Zhou, Bing Hu
BACKGROUND: Both periostin (PN) and epidermal growth factor receptor (EGFR) can predict the prognosis of several carcinomas alone. However, coexpression of PN and EGFR in esophageal squamous cell carcinoma (ESCC) still remains unknown. We aimed to clarify their relationship with clinicopathological factors and prognostic significance of their coexpression in ESCC. PATIENTS AND METHODS: In this single-center retrospective study, immunohistochemistry was performed to evaluate the expression of PN and EGFR in ESCC and paracarcinomatous tissues of 83 patients...
2016: OncoTargets and Therapy
Hang Yang, Mona Helena Biermann, Jan Markus Brauner, Yi Liu, Yi Zhao, Martin Herrmann
Recent data suggest that NETosis plays a crucial role in the innate immune response and disturbs the homeostasis of the immune system. NETosis is a form of neutrophil-specific cell death characterized by the release of large web-like structures referred to as neutrophil extracellular traps (NETs). NETs are composed of DNA strands associated with histones and decorated with about 20 different proteins, including neutrophil elastase, myeloperoxidase, cathepsin G, proteinase 3, high mobility group protein B1, and LL37...
2016: Frontiers in Immunology
Hao Wang, Cheng Hang, Xi-Long Ou, Jin-Shan Nie, Yi-Tao Ding, Shi-Gui Xue, Hua Gao, Jian-Xin Zhu
BACKGROUND: Pancreatic cancer is currently one of the leading causes of cancer deaths without any effective therapies. Mir-145 has been found to be tumor-suppressive in various types of cancers. The aim of this study is to investigate the role of miR-145 in pancreatic cancer cells and explore its underlying mechanism. METHODS: Quantitative real time PCR was used to determine the expression level of miR-145 and angiopoietin-2 (Ang-2) mNRA, and the expression level of Ang-2 protein was measured by western blotting...
2016: Cancer Cell International
Jun-Ping Qin, Xiang-You Yu, Chuan-Yun Qian, Shu-Sheng Li, Tie-He Qin, Er-Zhen Chen, Jian-Dong Lin, Yu-Hang Ai, Da-Wei Wu, De-Xin Liu, Ren-Hua Sun, Zhen-Jie Hu, Xiang-Yuan Cao, Fa-Chun Zhou, Zhen-Yang He, Li-Hua Zhou, You-Zhong An, Yan Kang, Xiao-Chun Ma, Ming-Yan Zhao, Li Jiang, Yuan Xu, Bin Du
BACKGROUND: Urine output (UO) is an essential criterion of the Kidney Disease Improving Global Outcomes (KDIGO) definition and classification system for acute kidney injury (AKI), of which the diagnostic value has not been extensively studied. We aimed to determine whether AKI based on KDIGO UO criteria (KDIGOUO) could improve the diagnostic and prognostic accuracy, compared with KDIGO serum creatinine criteria (KDIGOSCr). METHODS: We conducted a secondary analysis of the database of a previous study conducted by China Critical Care Clinical Trial Group (CCCCTG), which was a 2-month prospective cohort study (July 1, 2009 to August 31, 2009) involving 3063 patients in 22 tertiary Intensive Care Units in Mainland of China...
2016: Chinese Medical Journal
Charlotte Björkenstam, Lisa Ekselius, Marie Berlin, Bengt Gerdin, Emma Björkenstam
OBJECTIVE: The influence of psychopathology on suicide method has revealed different distributions among different psychiatric disorders. However, evidence is still scarce. We hypothesized that having a diagnosis of personality disorder (PD) affect the suicide method, and that different PD clusters would influence the suicide method in different ways. In addition, we hypothesized that the presence of psychiatric and somatic co-morbidity also affects the suicide method. METHOD: We examined 25,217 individuals aged 15-64 who had been hospitalized in Sweden with a main diagnosis of PD the years 1987-2013 (N = 25,217)...
August 12, 2016: Journal of Psychiatric Research
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