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Corneal abrasion

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https://www.readbyqxmd.com/read/29422528/epothilone-b-speeds-corneal-nerve-regrowth-and-functional-recovery-through-microtubule-stabilization-and-increased-nerve-beading
#1
Hanqing Wang, Chengju Xiao, Dong Dong, Cuipei Lin, Yunxia Xue, Jun Liu, Mingjuan Wu, Jingxin He, Ting Fu, Hongwei Pan, Xinwei Jiao, Dingli Lu, Zhijie Li
The successful restoration of corneal innervation and function after a corneal injury is a clinically challenging issue. Structural and functional recovery after a nerve injury involves a complex series of steps in which microtubules play a key role. The aim of the current study was to investigate the effects of epothilone B (EpoB), a microtubule-stabilizing agent, on corneal innervation and the functional recovery of the corneal nerve in mice after corneal epithelial abrasion. The pretreatment of mice with EpoB has a remarkable effect on the stabilization of beta-III tubulin, as demonstrated by substantial increases in the visualization of beta-III tubulin, nerve beading, corneal reinnervation, and reaction to stimuli...
February 8, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29409802/corneal-abrasion-and-microbial-contamination-in-horses-following-general-anaesthesia-for-non-ocular-surgery
#2
Stefania Scarabelli, Dorina Timofte, Fernando Malalana, David Bardell
OBJECTIVE: To evaluate the incidence of corneal abrasions/ulceration and microbial contamination in horses undergoing general anaesthesia. STUDY DESIGN: Prospective, observational, clinical study. ANIMALS: A total of 40 client-owned healthy horses scheduled for elective non-ophthalmic procedures. METHODS: Conjunctival sac swabs were taken, fluorescein dye applied and digital images recorded from both eyes of the horses after preanaesthetic medication and 24 hours after recovery from general anaesthesia...
January 9, 2018: Veterinary Anaesthesia and Analgesia
https://www.readbyqxmd.com/read/29380788/reactivation-of-herpes-simplex-viral-keratitis-following-the-botulinum-toxin-injection
#3
Muralidhar Ramappa, Peter Y Jiya, Sunita Chaurasia, Milind Naik, Savitri Sharma
We describe a case of 55-year-old male farmer presented with recurrent corneal abrasions with a spastic entropion in the left eye. Superior cornea showed typical nummular opacities suggestive resolved herpetic eye diseases. On further enquiry, he had similar episodes in the past. Contralateral eye was essentially normal. Following the botulinum toxin injection for the management of spastic entropion, subject developed reactivation of herpetic necrotizing stromal keratitis. Diagnostic corneal scrapings were negative for herpes simplex virus-1 antigen by immunofluorescence assay and for DNA by molecular techniques...
February 2018: Indian Journal of Ophthalmology
https://www.readbyqxmd.com/read/29328794/corneal-abrasion-following-anaesthesia-for-non-ocular-surgical-procedures-a-case-controlled-study
#4
Anais L Carniciu, Melissa J Fazzari, Pauline Tabibian, Priti Batta, Ronald C Gentile, James H Grendell, Collin E Braithwaite, Nazanin Barzideh
The aim of this study was to identify risk factors associated with perioperative corneal abrasion at a single hospital in Mineola, New York (United States). A chart review was conducted of patients with perioperative corneal abrasion following non-ocular surgery and age-matched controls between June 2011 and November 2013. An age-stratified logistic regression model evaluated the association between corneal abrasion and potentially predisposing variables. The adjusted odds of a corneal abrasion occurring were 4...
November 2017: Journal of Perioperative Practice
https://www.readbyqxmd.com/read/29311358/pediatric-sports-and-recreation-related-eye-injuries-treated-in-us-emergency-departments
#5
Krystin N Miller, Christy L Collins, Thitphalak Chounthirath, Gary A Smith
OBJECTIVES: To investigate the epidemiologic characteristics of sports- and recreation-related eye injuries among children in the United States. METHODS: Data from the National Electronic Injury Surveillance System were analyzed in a retrospective study of children ≤17 years of age treated in US emergency departments for sports- and recreation-related eye injuries from 1990 to 2012. RESULTS: From 1990 through 2012, an estimated 441 800 (95% confidence interval: 378 868-504 733) children were treated in US emergency departments for sports- and recreation-related eye injuries, averaging 26...
January 8, 2018: Pediatrics
https://www.readbyqxmd.com/read/29302786/intraoperative-changes-in-corneal-structure-during-excimer-laser-phototherapeutic-keratectomy-ptk-assessed-by-intraoperative-optical-coherence-tomography
#6
Sebastian Siebelmann, Jens Horstmann, Paula Scholz, Björn Bachmann, Mario Matthaei, Manuel Hermann, Claus Cursiefen
PURPOSE: Excimer laser phototherapeutic keratectomy (PTK) is a safe treatment for superficial corneal opacities, e.g., in corneal dystrophies or degenerations. Nevertheless, no standardized treatment protocols are available and intraoperative monitoring was not possible, so far. Here we evaluate the potential benefits of the intraoperative assessment by microscope-integrated intraoperative optical coherence tomography (MI-OCT) of corneal optical properties during PTK. METHODS: Retrospective study of eight patients (one male, seven females; age range, 43-80 years, mean = 66...
January 4, 2018: Graefe's Archive for Clinical and Experimental Ophthalmology
https://www.readbyqxmd.com/read/29234230/traumatic-eye-ball-luxation-a-stepwise-approach-to-globe-salvage
#7
Himika Gupta, Srivalli Natarajan, Sushrut Vaidya, Shipra Gupta, Dinesh Shah, Raj Merchant, Shrikant Deshpande
Craniofacial trauma is often associated with orbital and ocular injuries. We report a case of a 21-year-old male with motor vehicular accident, orbital roof blow-in fracture, cerebrospinal fluid (CSF) leak, and left sided globe luxation with corneal abrasion and complete conjunctival denuding. The patient was managed by a multispeciality team and the eyeball was protected by amniotic membrane graft (AMG) biological dressing with novel use of inverted sterile metallic bowl as mechanical protection till the patient stabilized...
October 2017: Saudi Journal of Ophthalmology: Official Journal of the Saudi Ophthalmological Society
https://www.readbyqxmd.com/read/29234226/patterns-of-ophthalmic-emergencies-presenting-to-a-referral-hospital-in-medina-city-saudi-arabia
#8
Omar M Alabbasi, Maan Al-Barry, Raghad F Albasri, Haitham F Khashim, Mohammad M Aloufi, Mohammed F Abdulaal, Dareen W Alsaidalany, Adel S Alahmadi, Hanan Habeeb, Waseem A Aalam
Background: Data are required on ophthalmic cases that present to the emergency eye clinics in Madinah, Saudi Arabia for proper allocation of healthcare resources. Objectives: To determine the frequency and various diagnoses of patients presenting to the A&E at Ohud Hospital, Madinah, Saudi Arabia. Methods: Data was collected prospectively for all patients who presented to the A&E ophthalmology clinic from June 2014 to September 2014. The data was analyzed and presented using frequency of incidence and percentages...
October 2017: Saudi Journal of Ophthalmology: Official Journal of the Saudi Ophthalmological Society
https://www.readbyqxmd.com/read/29217021/practice-patterns-in-the-interdisciplinary-management-of-corneal-abrasions
#9
Michael Ross, Jean Deschênes
OBJECTIVE: To characterize the treatment and follow-up patterns of corneal abrasions at an academic health centre. METHODS: This is a retrospective review of 90 cases of corneal abrasions over a 2-year period at a tertiary care academic hospital, of which 75 were seen by the ophthalmology department. All consultations primarily for corneal abrasion, as determined by the emergency department physician, were included in the study. Information on treatment regimen, corneal findings by emergency and ophthalmology physicians, time between follow-ups, and final outcomes was collected...
December 2017: Canadian Journal of Ophthalmology. Journal Canadien D'ophtalmologie
https://www.readbyqxmd.com/read/29170308/11%C3%A2-topical-nsaids-for-analgesia-in-traumatic-corneal-abrasions-a-systematic-review-and-meta-analysis
#10
Annali Lawrenson, Abel Wakai
BACKGROUND: Traumatic corneal abrasions are common ocular presenTations in the ED. There is no consensus regarding the most appropriate analgesia for this condition. Topical non-steroidal anti-inflammatory drugs (NSAIDs) have been suggested as pain-relief to minimise systemic adverse events associated with oral analgesia. AIM: To identify and evaluate all randomised controlled trials (RCTs) comparing the use of topical NSAIDs with placebo or any alternative analgesic interventions in adults with traumatic corneal abrasions (including corneal abrasions arising from foreign body removal), to reduce pain, and its effects on healing time...
December 2017: Emergency Medicine Journal: EMJ
https://www.readbyqxmd.com/read/29156998/exposures-to-automatic-dishwashing-rinse-aids-reported-to-the-united-kingdom-national-poisons-information-service-2008-2016
#11
Rachael C Day, Sally M Bradberry, Euan A Sandilands, Simon H L Thomas, John P Thompson, Allister Vale
OBJECTIVE: To determine the toxicity of rinse aids which are used as drying aids to remove water from crockery. METHODS: Enquiries to the UK National Poisons Information Service (NPIS) were analysed retrospectively for the period January 2008 to December 2016. RESULTS: There were 855 enquiries relating to 828 patients; children aged 5 years or less accounted for 91.1%. Most exposures occurred from ingestion alone (n = 778, 94.0%), but 26 involved ingestion and other routes: 21 with skin contact, 3 with eye contact, and two with both skin and eye contact...
November 20, 2017: Clinical Toxicology
https://www.readbyqxmd.com/read/29053036/eyelid-syringocystadenoma-papilliferum-a-novel-presentation-with-major-review
#12
Michael C Tseng, Bijal Amin, Anne Barmettler
A major review of the literature of syringocystadenoma papilliferum's (SCAP's) presentation and management is presented. In addition, a case report of this unique diagnosis presenting as a corneal abrasion in a 66-year-old-male is included. This benign adnexal tumor of the apocrine glands is most commonly found in the face and neck. When found on the eyelids, these lesions are commonly misdiagnosed as basal cell carcinoma or cysts. Diagnosis is made based on histopathology. Treatment is complete excision of the lesion and this has a low recurrence rate...
October 20, 2017: Orbit
https://www.readbyqxmd.com/read/28984213/-superglue-instead-of-eye-ointment-the-sealed-eye-often-frightening-and-painful-generally-ends-well
#13
R H C Zegers
BACKGROUND: Not infrequently, patients mistakenly put glue in their eye. This often induces considerable emotional and physical reaction. CASE DESCRIPTION: A 20-year-old man came to the Emergency Department at night because he had mistaken a tube of superglue for his eye ointment and instilled the glue into his right eye. All the glue was removed, as were most of his eyelashes. The glue-induced corneal abrasion healed completely and the patient did not sustain any permanent injury...
2017: Nederlands Tijdschrift Voor Geneeskunde
https://www.readbyqxmd.com/read/28875742/medicated-ocular-bandages-and-corneal-health-potential-excipients-and-active-pharmaceutical-ingredients
#14
Ghada Zidan, Ilva D Rupenthal, Carol Greene, Ali Seyfoddin
Corneal blindness can occur due to improper healing of the corneal tissues after induced injury or abrasion which can be accidental, pathogenic, or after corneal surgery. Abnormal regulation of the healing mechanisms can lead to corneal opacity. Reducing inflammation and promoting epithelial wound healing are crucial for scar-free corneal recovery without eyesight complications. Current approaches for corneal wound healing involve amniotic membrane (AM) bandages, bandage contact lenses (BCL), and collagen shields in conjunction with frequent administration of therapeutic eye drops...
September 21, 2017: Pharmaceutical Development and Technology
https://www.readbyqxmd.com/read/28820791/teleophthalmic-approach-for-detection-of-corneal-diseases-accuracy-and-reliability
#15
Maria A Woodward, David C Musch, Christopher T Hood, Jonathan B Greene, Leslie M Niziol, V Swetha E Jeganathan, Paul P Lee
PURPOSE: Corneal and anterior segment diseases cause most of the urgent visits to eye care professionals. We evaluated the diagnostic accuracy of detecting corneal diseases using external photographs from 2 portable cameras for telemedicine purposes. METHODS: This is a prospective study of adults with a clinical diagnosis of corneal pathology including corneal abrasions, ulcers, scars, and pterygia. A cornea specialist provided the gold standard diagnosis by slit-lamp examination...
October 2017: Cornea
https://www.readbyqxmd.com/read/28792916/penetrating-injury-from-plastic-airsoft-pellet-shows-beam-hardening-artifact-on-computer-tomography
#16
Divakar Gupta, Tina D Tailor, Courtney Francis, Kalpana Kanal, Todd Klesert
PURPOSE: To describe a case of left eye corneal perforation, cataract, hyphema, and intraocular foreign body after airsoft pellet injury. METHODS: The authors reviewed the medical history and diagnostic imaging of a 12-year-old boy injured by a pellet from an airsoft gun. Typically, plastic airsoft pellets cause blunt trauma to the globe, which can lead to visual disability from corneal abrasion or hyphema. Initial computed tomography of the left orbit showed a 6...
December 19, 2016: Retinal Cases & Brief Reports
https://www.readbyqxmd.com/read/28749895/mechanical-modeling-of-a-keratoconic-cornea
#17
Jean Marc Perone, Jean Baptiste Conart, Pierre-Jean Bertaux, Nicolas Sujet-Perone, Nadia Ouamara, Maxime Sot, Jean Jacques Henry
PURPOSE: We created a laboratory model of a cornea that was subjected to various pressures and thermal and mechanical factors to better understand the genesis of keratoconus deformation. METHODS: A steel base allowed for fixation of circular multilaminated patches of araldite (10 cm in diameter, 5 mm thick) in which the corneal anatomy was modeled. The model was plunged into a steam room (374°F/3 bars of pressure for 1 h) to ensure thermal homogeneity and was subjected to pressure using compressed air...
October 2017: Cornea
https://www.readbyqxmd.com/read/28632575/clinical-profile-etiology-and-outcome-of-infantile-ocular-trauma-a-developing-country-perspective
#18
Vedang D Shah, Madhu Uddaraju, Amitabh Singh, Rashmi Ranjan Das
OBJECTIVE: The aim of this article was to study the clinical profile, etiology, and outcome of infantile ocular trauma in a developing country setting. METHODS: A retrospective study on corneal trauma in infants (≤12 months old) was undertaken in a tertiary care hospital during a 2-year period. An analysis of clinical profile, etiology, microbiological profile, clinical course, and outcome was studied. RESULTS: Seventy-six infants were included...
June 20, 2017: Pediatric Emergency Care
https://www.readbyqxmd.com/read/28516471/topical-non-steroidal-anti-inflammatory-drugs-for-analgesia-in-traumatic-corneal-abrasions
#19
REVIEW
Abel Wakai, John G Lawrenson, Annali L Lawrenson, Yongjun Wang, Michael D Brown, Michael Quirke, Omar Ghandour, Ryan McCormick, Cathal D Walsh, Ahmed Amayem, Eddy Lang, Nick Harrison
BACKGROUND: Traumatic corneal abrasions are relatively common and there is a lack of consensus about analgesia in their management. It is therefore important to document the clinical efficacy and safety profile of topical ophthalmic non-steroidal anti-inflammatory drugs (NSAIDs) in the management of traumatic corneal abrasions. OBJECTIVES: To identify and evaluate all randomised controlled trials (RCTs) comparing the use of topical NSAIDs with placebo or any alternative analgesic interventions in adults with traumatic corneal abrasions (including corneal abrasions arising from foreign body removal), to reduce pain, and its effects on healing time...
May 18, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28509673/immune-responses-to-invasive-aspergillosis-new-understanding-and-therapeutic-opportunities
#20
Tobias M Hohl
PURPOSE OF REVIEW: Invasive aspergillosis is a worldwide disease that primarily affects immune-compromised patients, agricultural workers with corneal abrasions, individuals with structural lung disease, and patients with primary immune deficiency. The critical function of the immune system is to prevent the germination of airborne conidia into tissue-invasive hyphae. This review covers recent advances that shape our understanding of anti-Aspergillus immunity at the molecular and cellular level...
August 2017: Current Opinion in Infectious Diseases
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