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Corneal abrasion

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https://www.readbyqxmd.com/read/28221291/ophthalmic-manifestations-of-facial-dog-bites-in-children
#1
Emily M Bratton, Liliya Golas, Leslie A Wei, Brett W Davies, Vikram D Durairaj
PURPOSE: To characterize ophthalmic manifestations and periocular injuries of pediatric facial dog bites. METHODS: A retrospective review of all children younger than 18 years who sought medical attention after a dog bite to the face between January 1, 2003 and May 22, 2014 was performed at a large tertiary pediatric hospital. Data on type and location of injury, surgical intervention, and complications were collected. RESULTS: A total of 1,989 children aged 0...
February 17, 2017: Ophthalmic Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/28187472/-epi-bowman-keratectomy-clinical-evaluation-of-a-new-method-of-surface-ablation
#2
S Taneri, S Kießler, A Rost, T Schultz, M Elling, B Dick
Purpose A new device for epithelial abrasion before excimer laser surface ablation or corneal cross-linking (CXL) has recently been introduced (Epi-Clear™, Orca Surgical, Kiryat-Shmona, Israel). We have reviewed the literature on the clinical results, potential benefits and drawbacks of this instrument, compared to other methods of epithelial removal. Method Literature search for "Epi-Bowman Keratectomy", "Epi-clear", and "Epikeratome" yielded 1 peer-review publication, 1 non-peer-review publication, 18 posters and presentations at international conferences (European Society of Cataract and Refractive Surgeons [ESCRS] and American Society of Cataract and Refractive Surgery [ASCRS]) on the use of the Epi-Clear™ device before surface ablation, 2 posters on the use of Epi-Clear before corneal crosslinking and 1 presentation on the experimental use of Epi-Clear for removal of a pterygium...
February 10, 2017: Klinische Monatsblätter Für Augenheilkunde
https://www.readbyqxmd.com/read/28120849/ccr2-and-ccr2-corneal-macrophages-exhibit-distinct-characteristics-and-balance-inflammatory-responses-after-epithelial-abrasion
#3
J Liu, Y Xue, D Dong, C Xiao, C Lin, H Wang, F Song, T Fu, Z Wang, J Chen, H Pan, Y Li, D Cai, Z Li
Macrophages are distributed throughout the body and are crucial for the restoration of damaged tissues. However, their characteristics in the cornea and roles in the repair of corneal injures are unclear. Here we show that corneal macrophages can be classified as CCR2(-) macrophages, which already exist in the cornea at embryonic day 12.5 (E12.5) and are similar to yolk sac-derived macrophages, microglia, in phenotype and gene expression, and CCR2(+) macrophages, which do not appear in the cornea until E17...
January 25, 2017: Mucosal Immunology
https://www.readbyqxmd.com/read/28106291/ocular-effects-of-sulfur-mustard-and-therapeutic-approaches-a-review
#4
Yunes Panahi, Seyyed Mahdi Rajaee, Amirhossein Sahebkar
Sulfur mustard (SM) is a strong blistering, highly reactive, lipophilic chemical war agent that causes injury in different organs including the skin, eyes and respiratory tract. The Eyes are especially susceptible to the consequences of SM poisoning because of the aqueous and mucosal nature of conjunctiva and cornea. DNA alkylation and depletion of glutathione, are the most important mechanisms of SM action in the eye injuries. Acute clinical symptoms are including decrease in visual acuity, dryness, photophobia, blepharospasm, conjunctivitis and complaints of foreign body sensation and soreness that gradually progress to severe ocular pain...
January 20, 2017: Journal of Cellular Biochemistry
https://www.readbyqxmd.com/read/28097921/how-to-care-for-a-patient-s-eyes-in-critical-care-settings
#5
Janet Marsden, Richard Davies
Rationale and key points Eye care is an important aspect of the nursing management of patients who are critically ill. All patients in acute care settings with absent or compromised eye defence mechanisms are at risk of eye complications and ocular surface disease. This article aims to assist nurses to care for the eyes of patients in critical care settings to enable early detection and routine management of ophthalmic issues, thereby avoiding visual compromise on patient discharge from critical care settings...
December 14, 2016: Nursing Standard
https://www.readbyqxmd.com/read/28026813/-mechanisms-of-perioperative-corneal-abrasions-alterations-in-tear-film-proteome
#6
E Yu Zernii, O S Gancharova, I E Ishutina, V E Baksheeva, M O Golovastova, E I Kabanova, M S Savchenko, M V Serebryakova, L F Sotnikova, A A Zamyatnin, P P Philippov, I I Senin
Perioperative corneal abrasion is an ophthalmic complication commonly found in patients underwent general anesthesia. In this study, correlations between development of corneal injury and proteomic changes in tear film during general anesthesia were examined using an animal (rabbit) model. Being started after 1-h anesthesia, the process of accumulation of pathological changes in the cornea unequivocally led clinically significant abrasions following 3-6 h of the narcosis. The corneal damage was associated with alterations in profiles of major proteins of the tear film...
November 2016: Biomedit︠s︡inskai︠a︡ Khimii︠a︡
https://www.readbyqxmd.com/read/27989569/comparison-of-the-effects-of-various-lubricant-eye-drops-on-the-in-vitro-rabbit-corneal-healing-and-toxicity
#7
R Michael Dutescu, Claudia Panfil, Norbert Schrage
Ingredients of lubricant eye drops are potentially harmful to the ocular surface. The products Optive, Optive Fusion, Neopt were tested regarding corneal irritability versus Vismed Multi and 0.01% benzalkonium chloride as negative and positive control, respectively. Formulas (30-40μl per hour) were applied hourly in-vitro for six days on rabbit corneas (n=5, per product) cultured in artificial anterior chambers (EVEIT system). Initially, four corneal abrasions (2.4-4.6mm(2)) were induced. All defects were monitored during drop application by fluorescein stains and photographs...
December 15, 2016: Experimental and Toxicologic Pathology: Official Journal of the Gesellschaft Für Toxikologische Pathologie
https://www.readbyqxmd.com/read/27893577/a-novel-classification-system-for-injuries-after-electronic-cigarette-explosions
#8
Scott B Patterson, Allison R Beckett, Alicia Lintner, Carly Leahey, Ashley Greer, Sidney B Brevard, Jon D Simmons, Steven A Kahn
Electronic cigarettes (e-cigarettes) contain lithium batteries that have been known to explode and/or cause fires that have resulted in burn injury. The purpose of this article is to present a case study, review injuries caused by e-cigarettes, and present a novel classification system from the newly emerging patterns of burns. A case study was presented and online media reports for e-cigarette burns were queried with search terms "e-cigarette burns" and "electronic cigarette burns." The reports and injury patterns were tabulated...
January 2017: Journal of Burn Care & Research: Official Publication of the American Burn Association
https://www.readbyqxmd.com/read/27856946/eye-trauma-in-laurel-and-hardy-movies-another-nice-mess
#9
Lara DA Zegers, Richard Hc Zegers
BACKGROUND AND AIMS: One of the characteristics in Laurel and Hardy films is a lot of physical violence. The present study examines the occurrence of eye trauma in Laurel and Hardy movies and discusses the impact they could have been had if the films were set in reality. METHODS AND RESULTS: All 92 movies starring Laurel and Hardy as a pair in leading roles were watched together by the authors and were scored for any eye trauma. Eighty-eight eye traumas happened, of which 48% were directed at Hardy...
November 2016: Scottish Medical Journal
https://www.readbyqxmd.com/read/27818315/il-20-promotes-epithelial-healing-of-the-injured-mouse-cornea
#10
Wanyu Zhang, Sri Magadi, Zhijie Li, C Wayne Smith, Alan R Burns
After corneal epithelial injury, the ensuing inflammatory response is necessary for efficient wound healing. While beneficial healing effects are attributed to recruited neutrophils and platelets, dysregulated inflammation (too little or too much) is associated with impaired wound healing. The purpose of this study was to use an established C57BL/6J mouse model of corneal injury to evaluate the potential modulatory role of interleukin-20 (IL-20) on the inflammatory and healing responses to epithelial wounding...
November 3, 2016: Experimental Eye Research
https://www.readbyqxmd.com/read/27766386/-botulinum-toxin-a%C3%A2-induced-protective-ptosis-for-the-treatment-of-recurrent-epithelial-defects-in-neurotrophic-keratopathy
#11
A Schilimow, B Wiechens
In this article, a case of recurrent epithelial defects in neurotrophic keratopathy is described. Multiple abrasions of the corneal epithelium with a therapeutic contact lens, corneal stitches, and amniotic membrane transplantation in combination with artificial tears brought only short-term success. However, a botulinum toxin A induced protective ptosis could finally achieve permanent epithelial closure. As this case shows, protective ptosis can be a promising approach in spite of multiple previous ineffective therapeutic efforts...
October 20, 2016: Der Ophthalmologe: Zeitschrift der Deutschen Ophthalmologischen Gesellschaft
https://www.readbyqxmd.com/read/27759581/outcomes-of-an-intravitreal-injection-clinic
#12
Elizabeth A Atchison, Ahmed F Omar, Raymond Iezzi, Andrew J Barkmeier, Sophie J Bakri
PURPOSE: To examine the safety outcomes of an intravitreal injection-only clinic where patients needing long-term anti-vascular endothelial growth factor therapy are treated with injections at a predetermined interval for a set number of injections without an accompanying clinic visit. METHODS: This is a retrospective chart review of all patients with exudative macular degeneration treated in an intravitreal injection clinic over a 4-year period. Data on the outcome measures of interest were gathered from electronic medical records...
October 18, 2016: Retina
https://www.readbyqxmd.com/read/27601872/correlation-between-weather-and-incidence-of-selected-ophthalmological-diagnoses-a-database-analysis
#13
Christoph Kern, Karsten Kortüm, Michael Müller, Florian Raabe, Wolfgang Johann Mayer, Siegfried Priglinger, Thomas Christian Kreutzer
PURPOSE: Our aim was to correlate the overall patient volume and the incidence of several ophthalmological diseases in our emergency department with weather data. PATIENTS AND METHODS: For data analysis, we used our clinical data warehouse and weather data. We investigated the weekly overall patient volume and the average weekly incidence of all encoded diagnoses of "conjunctivitis", "foreign body", "acute iridocyclitis", and "corneal abrasion". A Spearman's correlation was performed to link these data with the weekly average sunshine duration, temperature, and wind speed...
2016: Clinical Ophthalmology
https://www.readbyqxmd.com/read/27599540/utilization-of-ophthalmology-specific-emergency-department-services
#14
Jayanth Sridhar, Ryan F Isom, Joyce C Schiffman, Luz Ajuria, Laura C Huang, Daniel Gologorsky, James T Banta
OBJECTIVE: To describe utilization trends of an ophthalmology-specific emergency department (ED). METHODS: Prospective cohort study of new patients presenting in the ophthalmology ED for at least a 30-day period in the spring of each year for five consecutive years (2010-14) at a university referral center. A data form, including information about the ED visit and patient demographics, was included in each patient chart. Data were analyzed with Pearson chi-square test and multiple logistic regression...
September 6, 2016: Seminars in Ophthalmology
https://www.readbyqxmd.com/read/27584715/effect-of-a-matrix-therapy-agent-on-corneal-epithelial-healing-after-standard-collagen-cross-linking-in-patients-with-keratoconus-a-randomized-clinical-trial
#15
Ahmed M Bata, Katarzyna J Witkowska, Piotr A Wozniak, Klemens Fondi, Gerald Schmidinger, Niklas Pircher, Stephan Szegedi, Valentin Aranha Dos Santos, Anca Pantalon, René M Werkmeister, Gerhard Garhofer, Leopold Schmetterer, Doreen Schmidl
Importance: Corneal abrasions are frequent after standard (epithelium-off [epi-off]) corneal collagen cross-linking (CXL) in patients with progressive keratoconus. A new matrix therapy agent (ReGeneraTing Agent [RGTA]) has been developed to promote corneal wound healing. Objective: To assess the effect of the new type of matrix therapy agent on corneal wound healing after epi-off CXL in patients with keratoconus. Design, Setting, and Participants: This double-masked randomized clinical trial enrolled 40 patients with keratoconus undergoing epi-off CXL from July 18, 2014, to October 21, 2015, when the last follow-up was completed...
October 1, 2016: JAMA Ophthalmology
https://www.readbyqxmd.com/read/27583662/abrasions-planned-defects-and-persistent-epithelial-defects-in-corneal-epithelial-wound-healing
#16
Bennie H Jeng
No abstract text is available yet for this article.
October 1, 2016: JAMA Ophthalmology
https://www.readbyqxmd.com/read/27527833/predatory-bacteria-are-nontoxic-to-the-rabbit-ocular-surface
#17
Eric G Romanowski, Nicholas A Stella, Kimberly M Brothers, Kathleen A Yates, Martha L Funderburgh, James L Funderburgh, Shilpi Gupta, Sonal Dharani, Daniel E Kadouri, Robert M Q Shanks
Given the increasing emergence of antimicrobial resistant microbes and the near absent development of new antibiotic classes, innovative new therapeutic approaches to address this global problem are necessary. The use of predatory bacteria, bacteria that prey upon other bacteria, is gaining interest as an "out of the box" therapeutic treatment for multidrug resistant pathogenic bacterial infections. Before a new antimicrobial agent is used to treat infections, it must be tested for safety. The goal of this study was to test the tolerability of bacteria on the ocular surface using in vitro and in vivo models...
2016: Scientific Reports
https://www.readbyqxmd.com/read/27457359/patching-for-corneal-abrasion
#18
REVIEW
Chris H L Lim, Angus Turner, Blanche X Lim
BACKGROUND: Published audits have demonstrated that corneal abrasions are a common presenting eye complaint. Eye patches are often recommended for treating corneal abrasions despite the lack of evidence for their use. This systematic review was conducted to determine the effects of the eye patch when used to treat corneal abrasions. OBJECTIVES: The objective of this review was to assess the effects of patching for corneal abrasion on healing and pain relief. SEARCH METHODS: We searched CENTRAL (which contains the Cochrane Eyes and Vision Trials Register) (2016, Issue 4), Ovid MEDLINE, Ovid MEDLINE In-Process and Other Non-Indexed Citations, Ovid MEDLINE Daily, Ovid OLDMEDLINE (January 1946 to May 2016), EMBASE (January 1980 to May 2016), Latin American and Caribbean Health Sciences Literature Database (LILACS) (January 1982 to May 2016), System for Information on Grey Literature in Europe (OpenGrey) (January 1995 to May 2016), the ISRCTN registry (www...
July 26, 2016: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/27405815/intranasal-delivery-of-nanomicelle-curcumin-promotes-corneal-epithelial-wound-healing-in-streptozotocin-induced-diabetic-mice
#19
Chuanlong Guo, Mengshuang Li, Xia Qi, Guiming Lin, Fenghua Cui, Fengjie Li, Xianggen Wu
Corneal nerves are mainly derived from the ophthalmic branch of the trigeminal ganglion (TG). Corneal neuropathy contributes to epithelial degenerative changes in diabetic keratopathy. Efficient drug delivery to TG may be beneficial for the treatment of diabetic keratopathy. This article described intranasal delivery of nanomicelle curcumin to correct pathophysiological conditions in TG to promote corneal epithelial/nerve wound healing in streptozotocin-induced diabetic mice. A diabetic mice model with corneal epithelium abrasion was established...
2016: Scientific Reports
https://www.readbyqxmd.com/read/27367514/longitudinal-changes-to-tight-junction-expression-and-endothelial-cell-integrity-in-a-mouse-model-of-sterile-corneal-inflammation
#20
Laura E Downie, Janet Choi, Jeremiah K H Lim, Holly R Chinnery
PURPOSE: We previously reported that applying toll-like receptor (TLR) ligands to an injured cornea induces corneal edema at 24 hours, which subsides by 1 week. We tested the hypotheses that endothelial expression of the tight-junction protein, zonula occludens-1 (ZO-1), would be altered during experimental sterile corneal inflammation and that endothelial cell density (ECD) would remain unaffected. METHODS: Anesthetized C57BL/6J mice received central 1-mm corneal abrasions followed by topical application of saline or cytosine-phosphate-guanosine oligodeoxynucleotide (CpG-ODN, TLR-9 agonist)...
June 1, 2016: Investigative Ophthalmology & Visual Science
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