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https://www.readbyqxmd.com/read/28088485/semantic-attributes-are-encoded-in-human-electrocorticographic-signals-during-visual-object-recognition
#1
Kyle Rupp, Matthew Roos, Griffin Milsap, Carlos Caceres, Christopher Ratto, Mark Chevillet, Nathan E Crone, Michael Wolmetz
Non-invasive neuroimaging studies have shown that semantic category and attribute information are encoded in neural population activity. Electrocorticography (ECoG) offers several advantages over non-invasive approaches, but the degree to which semantic attribute information is encoded in ECoG responses is not known. We recorded ECoG while patients named objects from 12 semantic categories and then trained high-dimensional encoding models to map semantic attributes to spectral-temporal features of the task-related neural responses...
January 11, 2017: NeuroImage
https://www.readbyqxmd.com/read/28074648/mispacking-and-the-fitness-landscape-of-the-green-fluorescent-protein-chromophore-milieu
#2
Shounak Banerjee, Christian D Schenkelberg, Thomas B Jordan, Julia M Reimertz, Emily E Crone, Donna E Crone, Christopher Bystroff
The auto-catalytic maturation of the chromophore in green fluorescent protein (GFP) was thought to require the precise positioning of the side chains surrounding it in the core of the protein, many of which are strongly conserved among homologous fluorescent proteins. In this study, we screened for green fluorescence in an exhaustive set of point mutations of seven residues that make up the chromophore microenvironment, excluding R96 and E222 because mutations of these positions have been previously characterized...
January 11, 2017: Biochemistry
https://www.readbyqxmd.com/read/28031794/negative-effects-of-density-on-space-use-of-small-mammals-differ-with-the-phase-of-the-masting-induced-population-cycle
#3
Michał Bogdziewicz, Rafał Zwolak, Lauren Redosh, Leszek Rychlik, Elizabeth E Crone
Home range size generally decreases with increasing population density, but testing how this relationship is influenced by other factors (e.g., food availability, kin structure) is a difficult task. We used spatially explicit capture-recapture models to examine how home range size varies with population density in the yellow-necked mouse (Apodemus flavicollis). The relationship between population density and home range size was studied at two distinct phases of population fluctuations induced by beech (Fagus sylvatica) masting: post-mast peak in abundance (first summer after mast, n = 2) and subsequent crash (second summer after mast, n = 2)...
December 2016: Ecology and Evolution
https://www.readbyqxmd.com/read/28026194/predicting-reading-and-mathematics-from-neural-activity-for-feedback-learning
#4
Sabine Peters, Mara Van der Meulen, Kiki Zanolie, Eveline A Crone
Although many studies use feedback learning paradigms to study the process of learning in laboratory settings, little is known about their relevance for real-world learning settings such as school. In a large developmental sample (N = 228, 8-25 years), we investigated whether performance and neural activity during a feedback learning task predicted reading and mathematics performance 2 years later. The results indicated that feedback learning performance predicted both reading and mathematics performance. Activity during feedback learning in left superior dorsolateral prefrontal cortex (DLPFC) predicted reading performance, whereas activity in presupplementary motor area/anterior cingulate cortex (pre-SMA/ACC) predicted mathematical performance...
January 2017: Developmental Psychology
https://www.readbyqxmd.com/read/27997678/tetraparetic-critically-ill-patients-show-electrophysiological-signs-of-myopathy
#5
Clarissa Crone
INTRODUCTION: Critically ill patients often develop tetraparesis. It has been debated whether this is caused by neuropathy, myopathy, or both. The aim was to determine the incidence of myopathy and neuropathy in weak patients in the intensive care unit by performing several electrophysiological examinations, including quantitative EMG. METHODS: Forty-nine patients referred for electrophysiological examination because of suspected critical illness-related weakness underwent electromyography (EMG), nerve conduction studies, and direct muscle stimulation...
December 20, 2016: Muscle & Nerve
https://www.readbyqxmd.com/read/27996965/rapid-tuning-shifts-in-human-auditory-cortex-enhance-speech-intelligibility
#6
Christopher R Holdgraf, Wendy de Heer, Brian Pasley, Jochem Rieger, Nathan Crone, Jack J Lin, Robert T Knight, Frédéric E Theunissen
Experience shapes our perception of the world on a moment-to-moment basis. This robust perceptual effect of experience parallels a change in the neural representation of stimulus features, though the nature of this representation and its plasticity are not well-understood. Spectrotemporal receptive field (STRF) mapping describes the neural response to acoustic features, and has been used to study contextual effects on auditory receptive fields in animal models. We performed a STRF plasticity analysis on electrophysiological data from recordings obtained directly from the human auditory cortex...
December 20, 2016: Nature Communications
https://www.readbyqxmd.com/read/27991897/pregnancy-leads-to-long-lasting-changes-in-human-brain-structure
#7
Elseline Hoekzema, Erika Barba-Müller, Cristina Pozzobon, Marisol Picado, Florencio Lucco, David García-García, Juan Carlos Soliva, Adolf Tobeña, Manuel Desco, Eveline A Crone, Agustín Ballesteros, Susanna Carmona, Oscar Vilarroya
Pregnancy involves radical hormone surges and biological adaptations. However, the effects of pregnancy on the human brain are virtually unknown. Here we show, using a prospective ('pre'-'post' pregnancy) study involving first-time mothers and fathers and nulliparous control groups, that pregnancy renders substantial changes in brain structure, primarily reductions in gray matter (GM) volume in regions subserving social cognition. The changes were selective for the mothers and highly consistent, correctly classifying all women as having undergone pregnancy or not in-between sessions...
December 19, 2016: Nature Neuroscience
https://www.readbyqxmd.com/read/27956570/spatial-temporal-functional-mapping-of-language-at-the-bedside-with-electrocorticography
#8
Abbas Babajani-Feremi, James W Wheless, James W Papanicolaou, Yujing Wang, Matthew S Fifer, Adeen Flinker, Anna Korzeniewska, Mackenzie C Cervenka, William S Anderson, Dana F Boatman-Reich, Nathan E Crone
No abstract text is available yet for this article.
December 13, 2016: Neurology
https://www.readbyqxmd.com/read/27923861/critical-stakeholder-determinants-to-the-implementation-of-intersectoral-community-approaches-targeting-childhood-obesity
#9
R M J J van der Kleij, M R Crone, R Reis, T G W M Paulussen
Several intersectoral community approaches targeting childhood obesity (IACOs) have been launched in the Netherlands. Translation of these approaches into practice is however arduous and implementation. We therefore studied the implementation of five IACOs in the Netherlands for one-and-a-half years. IACO implementation was evaluated via an adapted version of the MIDI questionnaire, consisting of 18 theory-based constructs. A response rate of 62% was obtained. A hierarchical multivariate linear regression model was used to analyse our data; the final regression model predicted 65% of the variance in adherence...
December 2016: Health Education Research
https://www.readbyqxmd.com/read/27913864/losing-a-battle-but-winning-the-war-moving-past-preference-performance-to-understand-native-herbivore-novel-host-plant-interactions
#10
Leone M Brown, Greg A Breed, Paul M Severns, Elizabeth E Crone
Introduced plants can positively affect population viability by augmenting the diet of native herbivores, but can negatively affect populations if they are subpar or toxic resources. In organisms with complex life histories, such as insects specializing on host plants, the impacts of a novel host may differ across life stages, with divergent effects on population persistence. Most research on effects of novel hosts has focused on adult oviposition preference and larval performance, but adult preference may not optimize offspring performance, nor be indicative of host quality from a demographic perspective...
December 2, 2016: Oecologia
https://www.readbyqxmd.com/read/27893236/training-in-the-adolescent-brain-an-fmri-training-study-on-divergent-thinking
#11
Sietske W Kleibeuker, Claire E Stevenson, Laura van der Aar, Sandy Overgaauw, Anna C van Duijvenvoorde, Eveline A Crone
Prior research suggests that adolescence is a time of enhanced sensitivity for practice and learning. In this study we tested the neural correlates of divergent thinking training in 15- to 16-year-old adolescents relative to an age-matched active control group. All participants performed an alternative uses task, a valid measure to test divergent thinking, while functional magnetic resonance imaging (fMRI) images were acquired before and after a training program. In between the 2 scanning sessions the experimental group completed 2 weeks of divergent thinking training (8 sessions) and the control group completed 2 weeks of rule switching training (8 session)...
November 28, 2016: Developmental Psychology
https://www.readbyqxmd.com/read/27886459/standardised-experiments-in-mutant-mice-reveal-behavioural-similarity-on-129s5-and-c57bl-6j-backgrounds
#12
Louie N van de Lagemaat, Lianne E Stanford, Charles Pettit, Douglas J Strathdee, Karen E Strathdee, Kathryn A Elsegood, David G Fricker, Mike D R Croning, Noboru H Komiyama, Seth G N Grant
Behavioural analysis of mice carrying engineered mutations is widely used to identify roles of specific genes in components of the mammalian behavioural repertoire. The reproducibility and robustness of phenotypic measures has become a concern that undermines the use of mouse genetic models for translational studies. Contributing factors include low individual study power, non-standardised behavioural testing, failure to address confounds and differences in genetic background of mutant mice. We have examined the importance of these factors using a statistically robust approach applied to behavioural data obtained from three mouse mutations on 129S5 and C57BL/6J backgrounds generated in a standardised battery of five behavioural assays...
November 25, 2016: Genes, Brain, and Behavior
https://www.readbyqxmd.com/read/27882498/parent-training-programs-for-ethnic-minorities-a-meta-analysis-of-adaptations-and-effect
#13
K van Mourik, M R Crone, M S de Wolff, R Reis
This meta-analysis focuses on parent training programs for ethnic minority families and reports on (i) the adaptation of program content and (ii) the process that informs these adaptations. Relevant studies are reviewed to determine the adaptations made and the impact of the adaptations on parenting and child outcomes. Studies were eligible for inclusion if they enrolled predominantly ethnic minority parents with children aged 0-12 years, used a randomized controlled trial design with post-intervention assessments, focused on group-based parent training programs and on prevention of parenting problems, and reported parenting behavior outcomes...
November 23, 2016: Prevention Science: the Official Journal of the Society for Prevention Research
https://www.readbyqxmd.com/read/27861755/longitudinal-changes-in-social-brain-development-processing-outcomes-for-friend-and-self
#14
Barbara R Braams, Eveline A Crone
Adolescence is an important time for social development during which friendships become more intimate and complex. In this functional magnetic resonance imaging (fMRI) study we tested how outcomes for friends are processed on the neural level across adolescence. Participants between 8 and 27 years of age were tested twice with a 2-year difference between the first (N = 299) and second (N = 254) time points. Participants performed a task in which they could win and lose money for themselves and their best friend...
November 11, 2016: Child Development
https://www.readbyqxmd.com/read/27859265/does-movement-behaviour-predict-population-densities-a-test-with-25-butterfly-species
#15
Cheryl B Schultz, B Guy Pe'er, Christine Damiani, Leone Brown, Elizabeth E Crone
Diffusion, which approximates a correlated random walk, has been used by ecologists to describe movement, and forms the basis for many theoretical models. However, it is often criticized as too simple a model to describe animal movement in real populations. We test a key prediction of diffusion models, namely, that animals should be more abundant in land cover classes through which they move more slowly. This relationship between density and diffusion has rarely been tested across multiple species within a given landscape...
November 17, 2016: Journal of Animal Ecology
https://www.readbyqxmd.com/read/27846824/group-based-prenatal-care-in-a-low-and-high-risk-population-in-the-netherlands-a-study-protocol-for-a-stepped-wedge-cluster-randomized-controlled-trial
#16
Birgit S van Zwicht, Matty R Crone, Jan M M van Lith, Marlies E B Rijnders
BACKGROUND: CenteringPregnancy (CP) is a multifaceted group based care-model integrated in routine prenatal care, combining health assessment, education, and support. CP has shown some positive results on perinatal outcomes. However, the effects are less obvious when limited to the results of randomized controlled trials: as there are few trials and there is a variation in reported outcomes. Furthermore, former research was mostly conducted in the United States of America and in specific (often high risk) populations...
November 15, 2016: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/27774764/amygdala-orbitofrontal-connectivity-predicts-alcohol-use-two-years-later-a-longitudinal-neuroimaging-study-on-alcohol-use-in-adolescence
#17
Sabine Peters, Jiska S Peper, Anna C K Van Duijvenvoorde, Barbara R Braams, Eveline A Crone
This study tested the relation between cortical-subcortical functional connectivity and alcohol consumption in adolescents using an accelerated longitudinal design, as well as normative developmental patterns for these measures. Participants between ages 8 and 27 completed resting-state neuroimaging scans at two time points separated by two years (N = 274 at T1, N = 231 at T2). In addition, participants between ages 12 and 27 reported on recent and lifetime alcohol use (N = 193 at T1, N = 244 at T2)...
October 23, 2016: Developmental Science
https://www.readbyqxmd.com/read/27762558/engineered-solution-liquid-solid-growth-of-a-treelike-1d-1d-tio2-nanotube-cdse-nanowire-heterostructure-photoelectrochemical-conversion-of-broad-spectrum-of-solar-energy
#18
Bratindranath Mukherjee, Swagotom Sarker, Eric Crone, Pawan Pathak, Vaidyanathan R Subramanian
This work presents a hitherto unreported approach to assemble a 1D oxide-1D chalcogenide heterostructured photoactive film. As a representative system, bismuth (Bi) catalyzed 1D CdSe nanowires are directly grown on anodized 1D TiO2 nanotube (T_NT). A combination of the reductive successive-ionic-layer-adsorption-reaction (R-SILAR) and the solution-liquid-solid (S-L-S) approach is implemented to fabricate this heterostructured assembly, reported in this 1D/1D form for the first time. XRD, SEM, HRTEM, and elemental mapping are performed to systematically characterize the deposition of bismuth on T_NT and the growth of CdSe nanowires leading to the evolution of the 1D/1D heterostructure...
December 7, 2016: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/27753220/longitudinal-links-between-childhood-peer-acceptance-and-the-neural-correlates-of-sharing
#19
Geert-Jan Will, Eveline A Crone, Pol A C van Lier, Berna Güroğlu
Childhood peer acceptance is associated with high levels of prosocial behavior and advanced perspective taking skills. Yet, the neurobiological mechanisms underlying these associations have not been studied. This functional magnetic resonance imaging study examined the neural correlates of sharing decisions in a group of adolescents who had a stable accepted status (n = 27) and a group who had a chronic rejected status (n = 19) across six elementary school grades. Both groups of adolescents played three allocation games in which they could share money with strangers with varying costs and profits to them and the other person...
October 17, 2016: Developmental Science
https://www.readbyqxmd.com/read/27651540/peers-and-parents-a-comparison-between-neural-activation-when-winning-for-friends-and-mothers-in-adolescence
#20
Barbara R Braams, Eveline A Crone
Rewards reliably elicit ventral striatum activity. More recently studies have shown that vicarious rewards elicit similar activation. Ventral striatum responses to rewards for self peak during adolescence. However, it is currently not well understood how ventral striatum responses to vicarious rewards develop. In this study, we test this question using behavioral and fMRI data. A total of 233 participants aged 9-26 years old played a gambling game in the scanner in which they could win or lose money for themselves, their best friend and mother...
September 20, 2016: Social Cognitive and Affective Neuroscience
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