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https://www.readbyqxmd.com/read/29153657/cardiac-magnetic-resonance-imaging-in-myocardial-inflammation-in-autoimmune-rheumatic-diseases-an-appraisal-of-the-diagnostic-strengths-and-limitations-of-the-lake-louise-criteria
#1
Sophie Mavrogeni, Juerg Schwitter, Albert van Rossum, Robin Nijveldt, Antony Aletras, Genovefa Kolovou, Gerald Pohost, Joao Lima
Myocardial inflammation in autoimmune rheumatic diseases (ARDs) is the endpoint of various pathophysiologic processes. The Lake Louise-criteria is the most popular approach for the diagnosis of myocarditis. However, due to the diversity of myocardial inflammation in ARDs, some issues should be acknowledged. Of the three Lake Louise indices, early and late gadolinium enhancement (EGE and LGE respectively) measurements may be affected by co-existing disease processes or be present due to a fibrotic ARD like systemic sclerosis, leaving T2-ratio as the only uniformly robust measurement across ARDs...
November 14, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/29151182/electrical-cardioversion-of-patients-with-implanted-pacemaker-or-cardioverter-defibrillator-results-of-a-survey-of-german-centers-and-systematic-review-of-the-literature
#2
J Lüker, A Sultan, T Plenge, J van den Bruck, C-H Heeger, S Meyer, K Mischke, R R Tilz, D Vollmann, G Nölker, B Schäffer, S Willems, D Steven
AIMS: A relevant number of patients presenting for electrical cardioversion carry a pacemaker (PM) or ICD. Case reports suggest a potential hazard of external cardioversion/defibrillation. The incidence of shock related device complications is unknown. No guidelines or recommendations by international medical societies for a cardioversion protocol of cardiovascular implantable electronic device (CIED) patients exist. We conducted a nationwide survey to gather real-world clinical data on the current clinical approach towards these patients during electrical cardioversion and to estimate the incidence of shock-related complications...
November 18, 2017: Clinical Research in Cardiology: Official Journal of the German Cardiac Society
https://www.readbyqxmd.com/read/29138937/effects-of-propofol-sedation-on-pacing-thresholds-results-from-an-observational-cohort-study
#3
Jakob Lüker, Arian Sultan, Tobias Plenge, Samuel Lee, Jan-Hendrik van den Bruck, Daniel Steven
BACKGROUND: Propofol is one of the most commonly used intravenous anaesthetic drugs for surgical procedures. The use of propofol for sedation is also common practice during endoscopic procedures, electrophysiology studies, and ablation procedures, as well as pacemaker and defibrillator implantation. It was found that propofol alters the electrophysiologic properties of the heart and its conduction system. The effects of propofol on pacing thresholds are unknown and could have implications for pacemaker (PM) and defibrillator (ICD) implantation procedures, as well as sedation and anaesthesia in PM and ICD patients in general...
November 14, 2017: Herzschrittmachertherapie & Elektrophysiologie
https://www.readbyqxmd.com/read/29122141/ecv-for-patients-with-aortic-stenosis-which-patient-will-benefit
#4
EDITORIAL
Raymond Y Kwong, Christopher M Kramer, Y Chandrashekhar
No abstract text is available yet for this article.
November 2017: JACC. Cardiovascular Imaging
https://www.readbyqxmd.com/read/29115801/the-relationship-between-the-vitamin-serum-25-oh-d-and-the-b12-concentrations-in-obese-women
#5
Nikola Curic, Branislava Ilincic, Natasa Milic, Velibor Cabarkapa, Stanislava Nikolic, Milica Medic-Stojanoska, Rinaldo Pellicano, Ludovico Abenavoli
BACKGROUND: In obesity, low levels of vitamin D (VD) and vitamin B12 (VB12), may be the result of different pathophysiological mechanisms, but the possible association between them has not yet been defined. The aim of this cross-sectional analysis was to investigate the possible relationship between serum 25-hydroxyvitamin D (25(OH)D) and VB12 levels in middle aged women. METHODS: In 80 women, we indirectly evaluated body composition and body volumes [extracellular fluid volume (ECV) and total body water (TBW)] by anthropometric and bioelectrical impedance analysis...
November 7, 2017: Minerva Medica
https://www.readbyqxmd.com/read/29106497/effect-of-candesartan-and-metoprolol-on-myocardial-tissue-composition-during-anthracycline-treatment-the-prada-trial
#6
Siri Lagethon Heck, Geeta Gulati, Pavel Hoffmann, Florian von Knobelsdorff-Brenkenhoff, Tryggve Holck Storås, Anne Hansen Ree, Berit Gravdehaug, Helge Røsjø, Kjetil Steine, Jürgen Geisler, Jeanette Schulz-Menger, Torbjørn Omland
Aims: Anthracycline treatment may cause myocyte loss and expansion of the myocardial extracellular volume (ECV) fraction by oedema and fibrosis. We tested the hypotheses that adjuvant treatment for early breast cancer with the anthracycline epirubicin is dose dependently associated with increased ECV fraction and total ECV, as well as reduced total myocardial cellular volume, and that these changes could be prevented by concomitant angiotensin or beta-adrenergic blockade. Methods and results: PRevention of cArdiac Dysfunction during Adjuvant breast cancer therapy (PRADA) was a 2 × 2 factorial, placebo-controlled, double-blinded trial of candesartan and metoprolol...
June 29, 2017: European Heart Journal Cardiovascular Imaging
https://www.readbyqxmd.com/read/29076585/cell-line-cross-contamination-a-detrimetal-issue-in-current-biomedical-research
#7
Armando Rojas, Ileana Gonzalez
In an article in the issue of September of Cell Biology International (Saladino et al. 2017), authors have used the cell line ECV-304 as a "human endothelial cell line". They even declare, as stated in text, that cell line were obtained from European Collection of Cell Cultures (ECACC), accordingly to the policy of the Journal.
October 27, 2017: Cell Biology International
https://www.readbyqxmd.com/read/29064123/in-vitro-antifungal-activity-of-amphotericin-b-and-eleven-comparators-against-aspergillus-terreus-species-complex
#8
Afsane Vaezi, Hamed Fakhim, Amir Arastehfar, Tahereh Shokohi, Mohammad T Hedayati, Sadegh Khodavaisy, Ali Rezaei-Matehkolaei, Parisa Badiee, Ferry Hagen, Cornelia Lass-Flörl, Eric Dannaoui, Jacques F Meis, Hamid Badali
Aspergillus terreus infections are difficult to treat because of the intrinsic resistance to amphotericin B, and higher mortality compared to infections caused by other Aspergillus species. The aim of the present study was to determine the in vitro antifungal activity of amphotericin B and eleven comparators against clinical (n = 36) and environmental (n = 45) A. terreus isolates. In vitro antifungal susceptibility was performed using the CLSI M38-A2 procedure. Amphotericin B exhibited the highest MICs (MIC range, 0...
October 24, 2017: Mycoses
https://www.readbyqxmd.com/read/29061184/assessment-of-reverse-remodeling-predicted-by-myocardial-deformation-on-tissue-tracking-in-patients-with-severe-aortic-stenosis-a-cardiovascular-magnetic-resonance-imaging-study
#9
Ji-Won Hwang, Sung Mok Kim, Sung-Ji Park, Eun Jeong Cho, Eun Kyoung Kim, Sung-A Chang, Sang-Chol Lee, Yeon Hyeon Choe, Seung Woo Park
BACKGROUND: The technique of tissue tracking with balanced steady-state free precession cine sequences was introduced, and allowed myocardial strain to be derived directly, offering advantages over traditional myocardial tagging. The aim of this study was to evaluate the correlation between reverse remodeling as an outcome and left ventricular strain using cardiovascular magnetic resonance imaging (CMR) tissue tracking, and to evaluate prediction of reverse remodeling by myocardial deformation in patients with severe aortic stenosis (AS)...
October 23, 2017: Journal of Cardiovascular Magnetic Resonance
https://www.readbyqxmd.com/read/29060136/estimation-of-peripheral-blood-volume-and-interstitial-volume-in-hemodialysis-patients-using-bioimpedance-techniques
#10
Fansan Zhu, Peter Kotanko, Nathan W Levin
This paper describes a method to estimate interstitial fluid volume and peripheral blood volume (BVP) in hemodialysis (HD) patients using whole body (wBIS) and calf (cBIS) bioimpedance spectroscopy techniques. The aim of this study was to evaluate the usefulness of the technique. Thirty five HD patients were studied pre and post HD. Extracellular volume (ECV) and total body water (TBW) were measured using wBIS and cBIS. The calf resistances at 5 kHz (R5) and at 1000 kHz (R1000) respectively reflect ECV and TBW in the calf...
July 2017: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/29057691/the-outcomes-and-risk-factors-of-fetal-bradycardia-associated-with-external-cephalic-version
#11
Fumio Suyama, Kohei Ogawa, Yukiko Tazaki, Terumi Miwa, Kosuke Taniguchi, Noriyuki Nakamura, Satomi Tanaka, Shinji Tanigaki, Haruhiko Sago
OBJECTIVE: To assess the outcomes and risk factors of fetal bradycardia after external cephalic version (ECV). METHODS: We performed a retrospective study of women who underwent ECV after 35 weeks of gestation in 2010-2016. We assessed the birth outcomes, including umbilical cord artery pH, according to the duration of fetal bradycardia and the risk factors for bradycardia. RESULTS: Among 390 cases, 189 (48.5%) cases showed fetal bradycardia during or immediately after ECV...
October 23, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/29050981/evolutional-change-in-epicardial-fat-and-its-correlation-with-myocardial-diffuse-fibrosis-in-heart-failure-patients
#12
Cho-Kai Wu, Hao-Yuan Tsai, Mao-Yuan M Su, Yi-Fan Wu, Juey-Jen Hwang, Jiunn-Lee Lin, Lian-Yu Lin, Jien-Jiun Chen
OBJECTIVES: The aim of this study was to characterize the characteristics of epicardial fat (EAT) in different stage heart failure (HF) patients and its relationship between cardiac fibrosis. BACKGROUND: EAT is visceral adipose tissue that possesses inflammatory properties. Inflammation and obesity are associated with cardiac fibrosis, but the relationship between cardiac fibrosis and EAT is unknown. METHODS: EAT volume was measured using cardiac magnetic resonance imaging (CMR) in 180 subjects: 58 patients with systolic HF, 63 patients with HF and preserved ejection fraction, and 59 patients without HF...
September 4, 2017: Journal of Clinical Lipidology
https://www.readbyqxmd.com/read/29045596/the-relationship-between-cardiovascular-magnetic-resonance-imaging-measurement-of-extracellular-volume-fraction-and-clinical-outcomes-in-adults-with-repaired-tetralogy-of-fallot
#13
Kate Hanneman, Andrew M Crean, Bernd J Wintersperger, Paaladinesh Thavendiranathan, Elsie T Nguyen, Camilla Kayedpour, Rachel M Wald
Aims: Our aims were to explore cardiac magnetic resonance quantification of myocardial extracellular volume (ECV) in adults with repaired tetralogy of Fallot (rTOF) when compared with healthy controls and to investigate the association between ECV and major adverse cardiovascular outcomes. Methods and results: We prospectively recruited adults with rTOF (n = 44, 59% male, 32.9 ± 13.6 years) and evaluated right ventricular (RV) and left ventricular (LV) ECV by pre/post-gadolinium T1 measurements (modified Look-Locker inversion recovery technique) on a 1...
October 17, 2017: European Heart Journal Cardiovascular Imaging
https://www.readbyqxmd.com/read/29042177/antibiotic-exposure-and-interpersonal-variance-mask-the-effect-of-ivacaftor-on-respiratory-microbiota-composition
#14
Anton Y Peleg, Jocelyn M Choo, Katherine M Langan, Deirdre Edgeworth, Dominic Keating, John Wilson, Geraint B Rogers, Tom Kotsimbos
BACKGROUND: G551D is a class III mutation of the cystic fibrosis transmembrane regulator (CFTR) that results in impaired chloride channel function in cystic fibrosis (CF). Ivacaftor, a CFTR-potentiating agent improves sweat chloride, weight, lung function, and pulmonary exacerbation rate in CF patients with G551D mutations, but its effect on the airway microbiome remains poorly characterised. METHODS: Twenty CF patients with at least one G551D mutation from a single centre were recruited to a 4month double-blind, placebo-controlled, crossover study of ivacaftor with 28days of active treatment...
October 15, 2017: Journal of Cystic Fibrosis: Official Journal of the European Cystic Fibrosis Society
https://www.readbyqxmd.com/read/29041923/fetal-heart-rate-abnormalities-during-and-after-external-cephalic-version-which-fetuses-are-at-risk-and-how-are-they-delivered
#15
Simone M Kuppens, Ida Smailbegovic, Saskia Houterman, Ingrid de Leeuw, Tom H Hasaart
BACKGROUND: Fetal heart rate abnormalities (FHR) during and after external cephalic version (ECV) are relatively frequent. They may raise concern about fetal wellbeing. Only occasionally they may lead to an emergency cesarean section. METHODS: Prospective cohort study in 980 women (> 34 weeks gestation) with a singleton fetus in breech presentation. During and after external cephalic version (ECV) FHR abnormalities were recorded. Obstetric variables and delivery outcome were evaluated...
October 17, 2017: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/29027210/oedema-fibrosis-in-duchenne-muscular-dystrophy-role-of-cardiovascular-magnetic-resonance-imaging
#16
REVIEW
Sophie Mavrogeni, Antigoni Papavasiliou, Katerina Giannakopoulou, George Markousis-Mavrogenis, Maria Roser Pons, Evangelos Karanasios, Ioannis Nikas, George Papadopoulos, Genovefa Kolovou, George P Chrousos
Duchenne muscular dystrophy (DMD) is an X-linked muscle disorder characterized by progressive, irreversible loss of cardiac and skeletal muscular function. Muscular enlargement in DMD is attributed to oedema, due to the increased cytoplasmic Na+ concentration. The aim in this review is to present the current experience and emphasize the role of cardiovascular magnetic resonance (CMR) in the diagnosis of this condition. DMD patients' survival depends on ventilatory assistance, as respiratory muscle dysfunction was the most common cause of death in the past...
October 13, 2017: European Journal of Clinical Investigation
https://www.readbyqxmd.com/read/29024124/examining-a-dual-process-model-of-desensitization-and-hypersensitization-to-community-violence-in-african-american-male-adolescents
#17
Noni K Gaylord-Harden, Grace J Bai, Dusan Simic
The purpose of the current study was to examine a dual-process model of reactivity to community violence exposure in African American male adolescents from urban communities. The model focused on desensitization and hypersensitization effects as well as desensitization and hypersensitization as predictors of aggressive behavior. Participants were 133 African American male high school students, mean age = 15.17 years, SD = 0.96. Participants completed measures of exposure to community violence, depressive symptoms, hyperarousal symptoms, aggressive beliefs, and aggressive behaviors at two time points...
October 2017: Journal of Traumatic Stress
https://www.readbyqxmd.com/read/29020257/reappraising-myocardial-fibrosis-in-severe-aortic-stenosis-an-invasive-and-non-invasive-study-in-133-patients
#18
Thomas A Treibel, Begoña López, Arantxa González, Katia Menacho, Rebecca S Schofield, Susana Ravassa, Marianna Fontana, Steven K White, Carmelo DiSalvo, Neil Roberts, Michael T Ashworth, Javier Díez, James C Moon
Aims: To investigate myocardial fibrosis (MF) in a large series of severe aortic stenosis (AS) patients using invasive biopsy and non-invasive imaging. Methods and results: One hundred thirty-three patients with severe, symptomatic AS accepted for surgical aortic valve replacement underwent cardiovascular magnetic resonance (CMR) with late gadolinium enhancement (LGE) and extracellular volume fraction (ECV) quantification. Intra-operative left ventricular (LV) biopsies were performed by needle or scalpel, yielding tissue with (n = 53) and without endocardium (n = 80), and compared with 10 controls...
July 22, 2017: European Heart Journal
https://www.readbyqxmd.com/read/28992817/clinical-recommendations-for-cardiovascular-magnetic-resonance-mapping-of-t1-t2-t2-and-extracellular-volume-a-consensus-statement-by-the-society-for-cardiovascular-magnetic-resonance-scmr-endorsed-by-the-european-association-for-cardiovascular-imaging-eacvi
#19
REVIEW
Daniel R Messroghli, James C Moon, Vanessa M Ferreira, Lars Grosse-Wortmann, Taigang He, Peter Kellman, Julia Mascherbauer, Reza Nezafat, Michael Salerno, Erik B Schelbert, Andrew J Taylor, Richard Thompson, Martin Ugander, Ruud B van Heeswijk, Matthias G Friedrich
Parametric mapping techniques provide a non-invasive tool for quantifying tissue alterations in myocardial disease in those eligible for cardiovascular magnetic resonance (CMR). Parametric mapping with CMR now permits the routine spatial visualization and quantification of changes in myocardial composition based on changes in T1, T2, and T2*(star) relaxation times and extracellular volume (ECV). These changes include specific disease pathways related to mainly intracellular disturbances of the cardiomyocyte (e...
October 9, 2017: Journal of Cardiovascular Magnetic Resonance
https://www.readbyqxmd.com/read/28980127/extracellular-volume-quantification-by-cardiac-magnetic-resonance-imaging-without-hematocrit-sampling-ready-for-prime-time
#20
Andreas A Kammerlander, Franz Duca, Christina Binder, Stefan Aschauer, Caroline Zotter-Tufaro, Matthias Koschutnik, Beatrice A Marzluf, Diana Bonderman, Julia Mascherbauer
BACKGROUND: Myocardial tissue characterization by cardiovascular magnetic resonance (CMR) T1 mapping currently receives increasing interest as a diagnostic tool in various disease settings. The T1-mapping technique allows non-invasive estimation of myocardial extracellular volume (ECV) using T1-times before and after gadolinium administration; however, for calculation of the myocardial ECV the hematocrit is needed, which limits its utility in routine application. Recently, the alternative use of the blood pool T1-time instead of the hematocrit has been described...
October 4, 2017: Wiener Klinische Wochenschrift
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