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Yih-Ling Tzeng, Anup K Datta, Cristy A Strole, Michael A Lobritz, Russell W Carlson, David S Stephens
The capsule of N. meningitidis serogroup B, (alpha2-->8)-linked polysialic acid and the capsules of other meningococcal serogroups and of other gram-negative bacterial pathogens are anchored in the outer membrane through a 1,2-diacylglycerol moiety. Previous work on the meningococcal cps complex in Escherichia coli K-12 indicated that deletion of genes designated lipA and lipB caused intracellular accumulation of hyperelongated capsule polymers lacking the phospholipid substitution. To better understand the role of lip and lipB in capsule expression in a meningococcal background, the location, sequence, and relationship to related bacterial capsule genes were defined and specific mutations in lipA and lipB were generated in the serogroup B meningococcal strain NMB...
March 2005: Infection and Immunity
No abstract text is available yet for this article.
July 1961: Journal of Laboratory and Clinical Medicine
No abstract text is available yet for this article.
August 1958: Journal of Laboratory and Clinical Medicine
Yih-Ling Tzeng, Anup Datta, Christy Strole, V S Kumar Kolli, Matthew R Birck, William P Taylor, Russell W Carlson, Ronald W Woodard, David S Stephens
We have identified and defined the function of kpsF of Neisseria meningitidis and the homologues of kpsF in encapsulated K1 and K5 Escherichia coli. KpsF was shown to be the arabinose-5-phosphate isomerase, an enzyme not previously identified in prokaryotes, that mediates the interconversion of ribulose 5-phosphate and arabinose 5-phosphate. KpsF is required for 3-deoxy-d-manno-octulosonic acid (Kdo) biosynthesis in N. meningitidis. Mutation of kpsF or the gene encoding the CMP-Kdo synthetase (kpsU/kdsB) in N...
July 5, 2002: Journal of Biological Chemistry
G Dewald, R Stallard, A Al Saadi, S Arnold, P I Bader, R Blough, K Chen, B R Elejalde, C J Harris, R R Higgins, G A Hoeltge, W T Hsu, V Kubic, D J McCorquodale, M A Micale, J W Moore, R M Phillips, S Scheib-Wixted, S Schwartz, S Siembieda, K Strole, P VanTuinen, G H Vance, A Wiktor, A Zinsmeister
Twenty-six laboratories used X and Y chromosome probes and the same procedures to process and examine 15,600 metaphases and 49,400 interphases from Phaseolus vulgaris-leucoagglutinin (PHA)-stimulated lymphocytes. In Part I, each laboratory scored 50 metaphases and 200 interphases from a normal male and a normal female from its own practice. In Part II, each laboratory scored 50 metaphases and 200 interphases on slides prepared by a central laboratory from a normal male and a normal female and three mixtures of cells from the male and female...
April 1, 1998: American Journal of Medical Genetics
S Spieker, V Ströle, A Sailer, A Boose, J Dichgans
We previously developed a method of tremor quantification using long-term electromyography registration of antagonistic forearm muscles that is reliable, sensitive, and specific for pathologic tremors. The present study demonstrates that tremor occurrence as measured by this method correlates well with clinical parameters of tremor in idiopathic Parkinson's disease (PD) and essential tremor (ET) (subscores of the Unified Parkinson's Disease Rating Scale for PD, tremor rating according to Bain et al. for ET)...
November 1997: Movement Disorders: Official Journal of the Movement Disorder Society
B A Barnes, F W Ackroyd, G E Battit, P A Kantrowitz, R H Schapiro, W E Strole, D P Todd, W V McDermott
No abstract text is available yet for this article.
July 1971: Annals of Surgery
W E Strole, W H Clark, K J Isselbacher
No abstract text is available yet for this article.
January 26, 1967: New England Journal of Medicine
J Reilly, J Ryan, W Strole, J Fischer
No abstract text is available yet for this article.
1976: Acta Chirurgica Scandinavica. Supplementum
J Reilly, J A Ryan, W Strole, J E Fischer
The effect of total parenteral nutrition on a group of thirty-four patients with inflammatory bowel disease over the past three and a half years was reviewed. Only patients in whom medical management had failed were included. Patients in whom the decision for surgery had been made and who were treated with total parenteral nutrition in an effort to prepare them for surgery were excluded. Of the group with Crohn's disease, those patients with small bowel involvement appeared to fare best; surgery was avoided in approximately 70 per cent of these admissions...
February 1976: American Journal of Surgery
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