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https://www.readbyqxmd.com/read/28646729/the-structure-of-ptsd-symptoms-according-to-dsm-5-and-idc-11-proposal-a-multi-sample-analysis
#1
M Cyniak-Cieciura, K Staniaszek, A Popiel, E Pragłowska, B Zawadzki
Posttraumatic stress disorder (PTSD) symptoms structure is a subject of ongoing debate since its inclusion in DSM-III classification in 1980. Different research on PTSD symptoms structure proved the better fit of four-factor and five-factor models comparing to the one proposed by DSM-IV. With the publication of DSM-5 classification, which introduced significant changes to PTSD diagnosis, the question arises about the adequacy of the proposed criteria to the real structure of disorder symptoms. Recent analyses suggest that seven-factor hybrid model is the best reflection of symptoms structure proposed to date...
May 4, 2017: European Psychiatry: the Journal of the Association of European Psychiatrists
https://www.readbyqxmd.com/read/28640451/cardiac-fibrosis-and-arrhythmogenesis
#2
My-Nhan Nguyen, Helen Kiriazis, Xiao-Ming Gao, Xiao-Jun Du
Myocardial injury, mechanical stress, neurohormonal activation, inflammation, and/or aging all lead to cardiac remodeling, which is responsible for cardiac dysfunction and arrhythmogenesis. Of the key histological components of cardiac remodeling, fibrosis either in the form of interstitial, patchy, or dense scars, constitutes a key histological substrate of arrhythmias. Here we discuss current research findings focusing on the role of fibrosis, in arrhythmogenesis. Numerous studies have convincingly shown that patchy or interstitial fibrosis interferes with myocardial electrophysiology by slowing down action potential propagation, initiating reentry, promoting after-depolarizations, and increasing ectopic automaticity...
June 18, 2017: Comprehensive Physiology
https://www.readbyqxmd.com/read/28639237/work-home-interference-perceived-total-workload-and-the-risk-of-future-sickness-absence-due-to-stress-related-mental-diagnoses-among-women-and-men-a-prospective-twin-study
#3
Pia Svedberg, Lisa Mather, Gunnar Bergström, Petra Lindfors, Victoria Blom
PURPOSE: Work-home interference has been proposed as an important explanation for sickness absence (SA). Previous studies show mixed results, have not accounted for familial factors (genetics and shared everyday environment), or investigated diagnosis specific SA. The aim was to study whether work-home interference and perceived total workload predict SA due to stress-related mental diagnoses, or SA due to other mental diagnoses, among women and men, when adjusting for various confounders and familial factors...
June 21, 2017: International Journal of Behavioral Medicine
https://www.readbyqxmd.com/read/28637098/uncovering-the-contribution-of-epigenetics-to-plant-phenotypic-variation-in-mediterranean-ecosystems
#4
REVIEW
F Balao, O Paun, C Alonso
Epigenetic signals can affect plant phenotype and fitness and be stably inherited across multiple generations. Epigenetic regulation plays a key role in the mechanisms of plant response to the environment without altering DNA sequence. As plants cannot adapt behaviourally or migrate instantly, such dynamic epigenetic responses may be particularly crucial for survival of plants within changing and challenging environments, such as the Mediterranean-Type Ecosystems (MTEs). These ecosystems suffer recurrent stressful events (warm and dry summers with associated fire regimes) that have selected for plants with similar phenotypic complex traits, resulting in similar vegetation growth forms...
June 21, 2017: Plant Biology
https://www.readbyqxmd.com/read/28616801/life-course-perspectives-on-the-onset-and-continuity-of-preventive-healthcare-behaviors
#5
REVIEW
Preecha Yingwattanakul, George P Moschis
Preventive healthcare is considered a cornerstone of good health and well-being that can play a major role in reducing a country's healthcare costs and improving both the length and quality of people's lives. Previous research on preventive healthcare behaviors has been predominantly cross-sectional, ignoring the dynamic nature of people's health behaviors over a full life span. As a result, the reasons for the development, stability, and changes of individuals' preventive healthcare behaviors over time remain relatively unknown...
June 14, 2017: Journal of Primary Prevention
https://www.readbyqxmd.com/read/28616250/potential-role-of-serum-and-urinary-biomarkers-in-diagnosis-and-prognosis-of-diabetic-nephropathy
#6
REVIEW
Carole G Campion, Oraly Sanchez-Ferras, Sri N Batchu
PURPOSE OF REVIEW: Diabetic nephropathy (DN) is a progressive kidney disease caused by alterations in kidney architecture and function, and constitutes one of the leading causes of end-stage renal disease (ESRD). The purpose of this review is to summarize the state of the art of the DN-biomarker field with a focus on the new strategies that enhance the sensitivity of biomarkers to predict patients who will develop DN or are at risk of progressing to ESRD. OBJECTIVE: In this review, we provide a description of the pathophysiology of DN and propose a panel of novel putative biomarkers associated with DN pathophysiology that have been increasingly investigated for diagnosis, to predict disease progression or to provide efficient personal treatment...
2017: Canadian Journal of Kidney Health and Disease
https://www.readbyqxmd.com/read/28611746/adaptations-to-high-salt-in-a-halophilic-protist-differential-expression-and-gene-acquisitions-through-duplications-and-gene-transfers
#7
Tommy Harding, Andrew J Roger, Alastair G B Simpson
The capacity of halophiles to thrive in extreme hypersaline habitats derives partly from the tight regulation of ion homeostasis, the salt-dependent adjustment of plasma membrane fluidity, and the increased capability to manage oxidative stress. Halophilic bacteria, and archaea have been intensively studied, and substantial research has been conducted on halophilic fungi, and the green alga Dunaliella. By contrast, there have been very few investigations of halophiles that are phagotrophic protists, i.e., protozoa...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/28606214/differential-susceptibility-effects-of-oxytocin-gene-oxt-polymorphisms-and-perceived-parenting-on-social-anxiety-among-adolescents
#8
Susanne Olofsdotter, Cecilia Åslund, Tomas Furmark, Erika Comasco, Kent W Nilsson
Social anxiety is one of the most commonly reported mental health problems among adolescents, and it has been suggested that parenting style influences an adolescent's level of anxiety. A context-dependent effect of oxytocin on human social behavior has been proposed; however, research on the oxytocin gene (OXT) has mostly been reported without considering contextual factors. This study investigated the interactions between parenting style and polymorphic variations in the OXT gene in association with social anxiety symptoms in a community sample of adolescents (n = 1,359)...
June 13, 2017: Development and Psychopathology
https://www.readbyqxmd.com/read/28603061/some-resonances-between-eastern-thought-and-integral-biomathics-in-the-framework-of-the-wlimes-formalism-for-modelling-living-systems
#9
REVIEW
Plamen L Simeonov, Andrée C Ehresmann
Forty-two years ago, Capra published "The Tao of Physics" (Capra, 1975). In this book (page 17) he writes: "The exploration of the atomic and subatomic world in the twentieth century has …. necessitated a radical revision of many of our basic concepts" and that, unlike 'classical' physics, the sub-atomic and quantum "modern physics" shows resonances with Eastern thoughts and "leads us to a view of the world which is very similar to the views held by mystics of all ages and traditions." This article stresses an analogous situation in biology with respect to a new theoretical approach for studying living systems, Integral Biomathics (IB), which also exhibits some resonances with Eastern thought...
June 8, 2017: Progress in Biophysics and Molecular Biology
https://www.readbyqxmd.com/read/28601395/manipulating-environmental-stresses-and-stress-tolerance-of-microalgae-for-enhanced-production-of-lipids-and-value-added-products-a-review
#10
REVIEW
Bailing Chen, Chun Wan, Muhammad Aamer Mehmood, Jo-Shu Chang, Fengwu Bai, Xinqing Zhao
Microalgae have promising potential to produce lipids and a variety of high-value chemicals. Suitable stress conditions such as nitrogen starvation and high salinity could stimulate synthesis and accumulation of lipids and high-value products by microalgae, therefore, various stress-modification strategies were developed to manipulate and optimize cultivation processes to enhance bioproduction efficiency. On the other hand, advancements in omics-based technologies have boosted the research to globally understand microalgal gene regulation under stress conditions, which enable further improvement of production efficiency via genetic engineering...
May 31, 2017: Bioresource Technology
https://www.readbyqxmd.com/read/28599850/tobacco-and-alcohol-use-during-adolescence-interactive-mechanisms-in-animal-models
#11
REVIEW
Yael Abreu-Villaça, Alex C Manhães, Thomas E Krahe, Claudio C Filgueiras, Anderson Ribeiro-Carvalho
There is a strong association between tobacco smoking and the consumption of alcoholic beverages. When compared to the effects of either drug on its own, the combined use may lead to worsened outcomes, such as less successful quitting attempts and increased likelihood of developing mood disorders. Co-consumption most frequently begins during adolescence, a developmental period that is characterized by an increased risk for substance use disorders. However, to date, most studies that have contributed to the current state of knowledge on the mechanisms that underlie tobacco or alcohol use/abuse, and their consequences, adopted adult animal models...
June 6, 2017: Biochemical Pharmacology
https://www.readbyqxmd.com/read/28588514/pathways-from-trauma-to-psychotic-experiences-a-theoretically-informed-model-of-posttraumatic-stress-in-psychosis
#12
Amy Hardy
In recent years, empirical data and theoretical accounts relating to the relationship between childhood victimization and psychotic experiences have accumulated. Much of this work has focused on co-occurring Posttraumatic Stress Disorder or putative causal mechanisms in isolation from each other. The complexity of posttraumatic stress reactions experienced in psychosis remains poorly understood. This paper therefore attempts to synthesize the current evidence base into a theoretically informed, multifactorial model of posttraumatic stress in psychosis...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/28578301/diurnal-cortisol-slopes-and-mental-and-physical-health-outcomes-a-systematic-review-and-meta-analysis
#13
REVIEW
Emma K Adam, Meghan E Quinn, Royette Tavernier, Mollie T McQuillan, Katie A Dahlke, Kirsten E Gilbert
Changes in levels of the stress-sensitive hormone cortisol from morning to evening are referred to as diurnal cortisol slopes. Flatter diurnal cortisol slopes have been proposed as a mediator between chronic psychosocial stress and poor mental and physical health outcomes in past theory and research. Surprisingly, neither a systematic nor a meta-analytic review of associations between diurnal cortisol slopes and health has been conducted to date, despite extensive literature on the topic. The current systematic review and meta-analysis examined associations between diurnal cortisol slopes and physical and mental health outcomes...
May 24, 2017: Psychoneuroendocrinology
https://www.readbyqxmd.com/read/28575526/reconstructing-the-suberin-pathway-in-poplar-by-chemical-and-transcriptomic-analysis-of-bark-tissues
#14
Meghan K Rains, Nayana Dilini Gardiyehewa de Silva, Isabel Molina
The tree bark periderm confers the first line of protection against pathogen invasion and abiotic stresses. The phellogen (cork cambium) externally produces cork (phellem) cells that are dead at maturity; while metabolically active, these tissues synthesize cell walls, as well as cell wall modifications, namely suberin and waxes. Suberin is a heteropolymer with aliphatic and aromatic domains, composed of acylglycerols, cross-linked polyphenolics and solvent-extractable waxes. Although suberin is essentially ubiquitous in vascular plants, the biochemical functions of many enzymes and the genetic regulation of its synthesis are poorly understood...
June 1, 2017: Tree Physiology
https://www.readbyqxmd.com/read/28573818/the-journey-between-brain-and-gut-a-systematic-review-of-psychological-mechanisms-of-treatment-effect-in-irritable-bowel-syndrome
#15
Sula Windgassen, Rona Moss-Morris, Joseph Chilcot, Alice Sibelli, Kimberley Goldsmith, Trudie Chalder
PURPOSE: Irritable bowel syndrome (IBS) is a functional gastrointestinal (GI) disorder characterized by abdominal pain and altered bowel habits. It is estimated to affect 10-22% of the UK population. The use of psychological interventions in IBS is increasingly empirically supported, but little is known about the mechanism of psychological treatment approaches. The present systematic review aimed to investigate the mechanisms of psychological treatment approaches applied to IBS. METHODS: The systematic review included studies conducting mediation analysis in the context of psychological interventions for IBS, focusing on the outcomes of symptom severity and/or quality of life (QoL)...
June 1, 2017: British Journal of Health Psychology
https://www.readbyqxmd.com/read/28573419/quantifying-cartilage-biomechanical-properties-using-a-linearized-frequency-domain-method
#16
A Gkousioudi, D S Tzeranis, G P Kanakaris, M Saloufas, L G Alexopoulos
Articular cartilage function relies on its unique mechanical behavior. Cartilage mechanics have been described by several analytic models, whose parameters are usually estimated by fitting their constitutive equations to stress-relaxation data. This procedure can be long and is prone to experimental and fitting errors. Τhis study describes a novel methodology for estimating the biomechanical properties of cartilage samples based on their linearized frequency response, derived by applying a series of small-amplitude harmonic displacements superimposed to a bias strain...
June 1, 2017: Annals of Biomedical Engineering
https://www.readbyqxmd.com/read/28566124/melatonin-for-prevention-of-erythema-and-oxidative-stress-in-response-to-ultraviolet-radiation
#17
Cecilie Scheuer
Skin damage induced by UVR is an escalating problem in dermatology, and increasing incidence of skin cancer, especially for non-melanoma skin cancer, has been reported worldwide. UVR from sun exposure and the production of reactive oxygen species (ROS) is known to be a pivotal factor in the aetiology of skin cancer. The pineal hormone melatonin is recognized as the most potent endogenous antioxidant. Melatonin conducts its antioxidant effects acting directly as a radical scavenger and indirectly by up regulation of antioxidant enzymes...
June 2017: Danish Medical Journal
https://www.readbyqxmd.com/read/28562503/rebooting-kirkpatrick-integrating-information-system-theory-into-the-evaluation-of-web-based-continuing-professional-development-interventions-for-interprofessional-education
#18
Nelson Shen, Shira Yufe, Omid Saadatfard, Sanjeev Sockalingam, David Wiljer
INTRODUCTION: Information system research has stressed the importance of theory in understanding how user perceptions can motivate the use and adoption of technology such as web-based continuing professional development programs for interprofessional education (WCPD-IPE). A systematic review was conducted to provide an information system perspective on the current state of WCPD-IPE program evaluation and how current evaluations capture essential theoretical constructs in promoting technology adoption...
April 2017: Journal of Continuing Education in the Health Professions
https://www.readbyqxmd.com/read/28562198/challenges-for-providing-health-care-in-traumatized-populations-barriers-for-ptsd-treatments-and-the-need-for-new-developments
#19
Evaldas Kazlauskas
There is a growing recognition about the effects of traumatic experiences on mental health worldwide. With ongoing conflicts, natural disasters, interpersonal violence, and other traumatic events it is estimated that approximately 70% of the global population have been exposed to at least one lifetime traumatic experience. Research shows a substantial proportion of survivors, especially in low- and middle-income countries, would have a posttraumatic stress disorder (PTSD). During recent decades effective evidence-based treatments for PTSD have been developed...
2017: Global Health Action
https://www.readbyqxmd.com/read/28560191/application-of-fuzzy-logic-in-oral-cancer-risk-assessment
#20
Ioana Scrobotă, Grigore Băciuț, Adriana Gabriela Filip, Bianca Todor, Florin Blaga, Mihaela Felicia Băciuț
BACKGROUND: The mapping of the malignization mechanism is still incomplete, but oxidative stress is strongly correlated to carcinogenesis. In our research, using fuzzy logic, we aimed to estimate the oxidative stress related-cancerization risk of the oral potentially malignant disorders. METHODS: Serum from 16 patients diagnosed (clinical and histopathological) with oral potentially malignant disorders (Dept. of Cranio-Maxillofacial Surgery and Radiology, "Iuliu Hațieganu" University of Medicine and Pharmacy, Cluj Napoca, Romania) was processed fluorometric for malondialdehyde and proton donors assays (Dept...
May 2017: Iranian Journal of Public Health
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