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Research Proposal on stress

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https://www.readbyqxmd.com/read/28432482/the-sensible-health-care-professional-a-care-ethical-perspective-on-the-role-of-caregivers-in-emotionally-turbulent-practices
#1
Vivianne Baur, Inge van Nistelrooij, Linus Vanlaere
This article discusses the challenging context that health care professionals are confronted with, and the impact of this context on their emotional experiences. Care ethics considers emotions as a valuable source of knowledge for good care. Thinking with care ethical theory and looking through a care ethical lens at a practical case example, the authors discern reflective questions that (1) shed light on a care ethical approach toward the role of emotions in care practices, and (2) may be used by practitioners and facilitators for care ethical reflection on similar cases, in the particular and concrete context where issues around emotional experiences arise...
April 21, 2017: Medicine, Health Care, and Philosophy
https://www.readbyqxmd.com/read/28428956/physiological-functions-of-the-cellular-prion-protein
#2
REVIEW
Andrew R Castle, Andrew C Gill
The prion protein, PrP(C), is a small, cell-surface glycoprotein notable primarily for its critical role in pathogenesis of the neurodegenerative disorders known as prion diseases. A hallmark of prion diseases is the conversion of PrP(C) into an abnormally folded isoform, which provides a template for further pathogenic conversion of PrP(C), allowing disease to spread from cell to cell and, in some circumstances, to transfer to a new host. In addition to the putative neurotoxicity caused by the misfolded form(s), loss of normal PrP(C) function could be an integral part of the neurodegenerative processes and, consequently, significant research efforts have been directed toward determining the physiological functions of PrP(C)...
2017: Frontiers in Molecular Biosciences
https://www.readbyqxmd.com/read/28402211/metabolomic-study-of-chardonnay-grapevines-double-stressed-with-esca-associated-fungi-and-drought
#3
Marta R M Lima, Antoinette F Machado, Walter D Gubler
Esca is a complex grapevine trunk disease associated with fungal infection of the xylem. However, the inconstancy of external symptoms and the ability of esca-associated fungi to inhabit grapevines without causing apparent disease suggests that abiotic factors might be involved in the disease. Water stress has been proposed to be one of the factors influencing esca symptom manifestation but the specific role played by water stress on esca development is unknown. We conducted a proton nuclear magnetic resonance spectroscopy-based metabolomic study aiming at unveiling drought-induced modifications in xylem sap composition that could contribute to esca-related infection progression...
April 12, 2017: Phytopathology
https://www.readbyqxmd.com/read/28401275/dimensionality-of-dsm-5-posttraumatic-stress-disorder-and-its-association-with-suicide-attempts-results-from-the-national-epidemiologic-survey-on-alcohol-and-related-conditions-iii
#4
Chiung M Chen, Young-Hee Yoon, Thomas C Harford, Bridget F Grant
BACKGROUND: Emerging confirmatory factor analytic (CFA) studies suggest that posttraumatic stress disorder (PTSD) as defined by the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5) is best characterized by seven factors, including re-experiencing, avoidance, negative affect, anhedonia, externalizing behaviors, and anxious and dysphoric arousal. The seven factors, however, have been found to be highly correlated, suggesting that one general factor may exist to explain the overall correlations among symptoms...
April 11, 2017: Social Psychiatry and Psychiatric Epidemiology
https://www.readbyqxmd.com/read/28377737/recognizing-moral-identity-as-a-cultural-construct
#5
Fanli Jia, Tobias Krettenauer
Current research on moral identity shows that moral identity predicts moral action in Western cultures but not in non-Western cultures. The present paper argues that this may be due to the fact that the concept of moral identity is culturally biased. In order to remedy this situation, we argue that researchers should broaden their scopes of inquiry by adding a cultural lens to their studies of moral identity. This change is important because although some concept of moral identity likely exists in all cultures, it may function in different ways and at different levels in each place...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/28377143/scales-used-to-rate-adult-patients-psycho-emotional-status-in-tooth-extraction-procedures-a-systematic-review
#6
REVIEW
I Astramskaitė, G Juodžbalys
The aim of this study was to review scales used to assess anxiety, stress, and pain in dental patients undergoing a tooth extraction procedure and to propose a novel psycho-emotional rating scale based on the relevant literature and our own experience. An electronic literature search was conducted of the National Library of Medicine database MEDLINE (Ovid) and EMBASE databases between January 2005 and April 2016. Sequential screening at the title/abstract and full-text levels was performed. The review included all human prospective or retrospective follow-up studies and clinical trials, cohort studies, case-control studies, and case series that demonstrated at least one scale used to measure tooth extraction anxiety, stress, or pain...
April 1, 2017: International Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/28373689/collaborative-meta-analysis-finds-no-evidence-of-a-strong-interaction-between-stress-and-5-httlpr-genotype-contributing-to-the-development-of-depression
#7
R C Culverhouse, N L Saccone, A C Horton, Y Ma, K J Anstey, T Banaschewski, M Burmeister, S Cohen-Woods, B Etain, H L Fisher, N Goldman, S Guillaume, J Horwood, G Juhasz, K J Lester, L Mandelli, C M Middeldorp, E Olié, S Villafuerte, T M Air, R Araya, L Bowes, R Burns, E M Byrne, C Coffey, W L Coventry, K A B Gawronski, D Glei, A Hatzimanolis, J-J Hottenga, I Jaussent, C Jawahar, C Jennen-Steinmetz, J R Kramer, M Lajnef, K Little, H M Zu Schwabedissen, M Nauck, E Nederhof, P Petschner, W J Peyrot, C Schwahn, G Sinnamon, D Stacey, Y Tian, C Toben, S Van der Auwera, N Wainwright, J-C Wang, G Willemsen, I M Anderson, V Arolt, C Åslund, G Bagdy, B T Baune, F Bellivier, D I Boomsma, P Courtet, U Dannlowski, E J C de Geus, J F W Deakin, S Easteal, T Eley, D M Fergusson, A M Goate, X Gonda, H J Grabe, C Holzman, E O Johnson, M Kennedy, M Laucht, N G Martin, M R Munafò, K W Nilsson, A J Oldehinkel, C A Olsson, J Ormel, C Otte, G C Patton, B W J H Penninx, K Ritchie, M Sarchiapone, J M Scheid, A Serretti, J H Smit, N C Stefanis, P G Surtees, H Völzke, M Weinstein, M Whooley, J I Nurnberger, N Breslau, L J Bierut
The hypothesis that the S allele of the 5-HTTLPR serotonin transporter promoter region is associated with increased risk of depression, but only in individuals exposed to stressful situations, has generated much interest, research and controversy since first proposed in 2003. Multiple meta-analyses combining results from heterogeneous analyses have not settled the issue. To determine the magnitude of the interaction and the conditions under which it might be observed, we performed new analyses on 31 data sets containing 38 802 European ancestry subjects genotyped for 5-HTTLPR and assessed for depression and childhood maltreatment or other stressful life events, and meta-analysed the results...
April 4, 2017: Molecular Psychiatry
https://www.readbyqxmd.com/read/28364840/status-inconsistency-in-groups-how-discrepancies-between-instrumental-and-expressive-status-result-in-symptoms-of-stress
#8
Hendrik Johan van de Brake, André Grow, Jan Kornelis Dijkstra
This study examines whether a mismatch between the positions that individuals hold in different status hierarchies results in symptoms of stress. Prior research has focused on inconsistencies between socioeconomic status dimensions (e.g., education and income) and did not find a significant relation between status inconsistency and stress. In this paper, we build on research on role differentiation and propose to study the effect of inconsistencies between instrumental status and expressive status in group contexts...
May 2017: Social Science Research
https://www.readbyqxmd.com/read/28362000/emergence-and-evolution-of-cooperation-under-resource-pressure
#9
María Pereda, Débora Zurro, José I Santos, Ivan Briz I Godino, Myrian Álvarez, Jorge Caro, José M Galán
We study the influence that resource availability has on cooperation in the context of hunter-gatherer societies. This paper proposes a model based on archaeological and ethnographic research on resource stress episodes, which exposes three different cooperative regimes according to the relationship between resource availability in the environment and population size. The most interesting regime represents moderate survival stress in which individuals coordinate in an evolutionary way to increase the probabilities of survival and reduce the risk of failing to meet the minimum needs for survival...
March 31, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28358559/understanding-reappraisal-as-a-multicomponent-process-the-psychological-health-benefits-of-attempting-to-use-reappraisal-depend-on-reappraisal-success
#10
Brett Q Ford, Helena R Karnilowicz, Iris B Mauss
When is reappraisal-reframing a situation's meaning to alter its emotional impact-associated with psychological health? To answer this question, we should consider that reappraisal is a multicomponent process that includes, first, deciding to attempt to use reappraisal and, second, implementing reappraisal with varying degrees of success. Although theories of emotion regulation suggest that both attempting reappraisal more frequently and implementing reappraisal more successfully are necessary to achieve greater psychological health, no research has directly tested this assumption...
March 30, 2017: Emotion
https://www.readbyqxmd.com/read/28357362/bacterial-outer-membrane-vesicle-biogenesis-a-new-mechanism-and-its-implications
#11
COMMENT
Sandro Roier, Franz G Zingl, Fatih Cakar, Stefan Schild
Outer membrane vesicle (OMV) release by Gram-negative bacteria has been observed and studied for decades. First considered as a by-product of cell lysis, it soon became evident that OMVs are actively secreted from the outer membrane (OM) of Gram-negative bacteria. Accordingly, these small particles (~ 10-300 nm in diameter) consist mainly of OM components like phospholipids (PLs), OM proteins, and lipopolysaccharides or lipooligosaccharides. However, OMVs may also comprise periplasmic, inner membrane, or cytoplasmic components...
May 10, 2016: Microbial Cell
https://www.readbyqxmd.com/read/28351484/hypocapnic-hypothesis-of-leigh-disease
#12
Ewa Pronicka
Leigh syndrome (LS) is a neurogenetic disorder of children caused by mutations in at least 75 genes which impair mitochondrial bioenergetics. The changes have typical localization in basal ganglia and brainstem, and typical histological picture of spongiform appearance, vascular proliferation and gliosis. ATP deprivation, free radicals and lactate accumulation are suspected to be the causes. Hypocapnic hypothesis proposed in the paper questions the energy deprivation as the mechanism of LS. We assume that the primary harmful factor is hypocapnia (decrease in pCO2) and respiratory alkalosis (increase in pH) due to hyperventilation, permanent or in response to stress...
April 2017: Medical Hypotheses
https://www.readbyqxmd.com/read/28345685/-carbon-nanotubes-characteristic-of-the-substance-biological-effects-and-occupational-exposure-levels
#13
REVIEW
Anna Maria Świdwińska-Gajewska, Sławomir Czerczak
Carbon nanotubes (CNTs) are a diverse group of nano-objects in terms of structure, size (length, diameter), shape and characteristics. The growing interest in these structures is due to the increasing number of people working in exposure to CNTs. Occupational exposure to carbon nanotubes may occur in research laboratories, as well as in plants producing CNTs and their nanocomposites. Carbon nanotubes concentration at the emission source may reach 107 particles/cm<sup>3</sup>. These values, however, are considerably reduced after the application of adequate ventilation...
March 24, 2017: Medycyna Pracy
https://www.readbyqxmd.com/read/28333692/application-of-olfactory-tissue-and-its-neural-progenitors-to-schizophrenia-and-psychiatric-research
#14
Joëlle Lavoie, Akira Sawa, Koko Ishizuka
PURPOSE OF REVIEW: The goal of this review article is to introduce olfactory epithelium-derived cell/tissue models as a promising surrogate system to study the molecular mechanisms implicated in schizophrenia and other neuropsychiatric disorders. Here, we particularly focus on the utility of their neural progenitors. RECENT FINDINGS: Recent investigations of the pathophysiology of schizophrenia using olfactory epithelium-derived tissue/cell models have provided insights about schizophrenia-associated alterations in neurodevelopment, stress response, and gene/protein expression regulatory pathways...
May 2017: Current Opinion in Psychiatry
https://www.readbyqxmd.com/read/28333525/a-potential-psychological-mechanism-linking-disaster-related-prenatal-maternal-stress-with-child-cognitive-and-motor-development-at-16-months-the-qf2011-queensland-flood-study
#15
Katrina M Moss, Gabrielle Simcock, Vanessa Cobham, Sue Kildea, Guillaume Elgbeili, David P Laplante, Suzanne King
Fetal exposure to prenatal maternal stress can have lifelong consequences, with different types of maternal stress associated with different areas of child development. Fewer studies have focused on motor skills, even though they are strongly predictive of later development across a range of domains. Research on mechanisms of transmission has identified biological cascades of stress reactions, yet links between psychological stress reactions are rarely studied. This study investigates the relationship between different aspects of disaster-related prenatal maternal stress and child cognitive and motor development, and proposes a cascade of stress reactions as a potential mechanism of transmission...
April 2017: Developmental Psychology
https://www.readbyqxmd.com/read/28324848/is-level-of-prematurity-a-risk-plasticity-factor-at-three-years-of-age
#16
Kristin Hadfield, Fearghal O'Brien, Aaron Gerow
Children born preterm have poorer outcomes than children born full-term, but the caregiving environment can ameliorate some of these differences. Recent research has proposed that preterm birth may be a plasticity factor, leading to better outcomes for preterm than full-term infants in higher quality environments. This analysis uses data from two waves of an Irish study of children (at 9 months and 3 years of age, n=11,134 children) and their caregivers (n=11,132 mothers, n=9998 fathers) to investigate differences in how caregiving affects social, cognitive, and motor skills between full-term, late preterm, and very preterm children...
March 18, 2017: Infant Behavior & Development
https://www.readbyqxmd.com/read/28314597/co-enrolment-of-participants-into-multiple-cancer-trials-benefits-and-challenges
#17
F H Cafferty, C Coyle, S Rowley, L Berkman, M MacKensie, R E Langley
Opportunities to enter patients into more than one clinical trial are not routinely considered in cancer research and experiences with co-enrolment are rarely reported. Potential benefits of allowing appropriate co-enrolment have been identified in other settings but there is a lack of evidence base or guidance to inform these decisions in oncology. Here, we discuss the benefits and challenges associated with co-enrolment based on experiences in the Add-Aspirin trial - a large, multicentre trial recruiting across a number of tumour types, where opportunities to co-enrol patients have been proactively explored and managed...
March 14, 2017: Clinical Oncology: a Journal of the Royal College of Radiologists
https://www.readbyqxmd.com/read/28304330/a-context-aware-s-health-service-system-for-drivers
#18
Jingkun Chang, Wenbin Yao, Xiaoyong Li
As a stressful and sensitive task, driving can be disturbed by various factors from the health condition of the driver to the environmental variables of the vehicle. Continuous monitoring of driving hazards and providing the most appropriate business services to meet actual needs can guarantee safe driving and make great use of the existing information resources and business services. However, there is no in-depth research on the perception of a driver's health status or the provision of customized business services in case of various hazardous situations...
March 17, 2017: Sensors
https://www.readbyqxmd.com/read/28300644/the-connective-tissue-phenotype-of-glaucomatous-cupping-in-the-monkey-eye-clinical-and-research-implications
#19
REVIEW
Hongli Yang, Juan Reynaud, Howard Lockwood, Galen Williams, Christy Hardin, Luke Reyes, Cheri Stowell, Stuart K Gardiner, Claude F Burgoyne
In a series of previous publications we have proposed a framework for conceptualizing the optic nerve head (ONH) as a biomechanical structure. That framework proposes important roles for intraocular pressure (IOP), IOP-related stress and strain, cerebrospinal fluid pressure (CSFp), systemic and ocular determinants of blood flow, inflammation, auto-immunity, genetics, and other non-IOP related risk factors in the physiology of ONH aging and the pathophysiology of glaucomatous damage to the ONH. The present report summarizes 20 years of technique development and study results pertinent to the characterization of ONH connective tissue deformation and remodeling in the unilateral monkey experimental glaucoma (EG) model...
March 12, 2017: Progress in Retinal and Eye Research
https://www.readbyqxmd.com/read/28299924/improvement-of-electrical-characteristics-and-stability-of-amorphous-indium-gallium-zinc-oxide-thin-film-transistors-using-nitrocellulose-passivation-layer
#20
Kwan Yup Shin, Young Jun Tak, Won-Gi Kim, Seonghwan Hong, Hyun Jae Kim
In this research, nitrocellulose is proposed as a new material for the passivation layers of amorphous indium gallium zinc oxide thin film transistors (a-IGZO TFTs). The a-IGZO TFTs with nitrocellulose passivation layers (NC-PVLs) demonstrate improved electrical characteristics and stability. The a-IGZO TFTs with NC-PVLs exhibit improvements in field-effect mobility (μFE) from 11.72 ± 1.14 to 20.68 ± 1.94 cm(2)/(V s), threshold voltage (Vth) from 1.85 ± 1.19 to 0.56 ± 0.35 V, and on/off current ratio (Ion/off) from (5...
April 4, 2017: ACS Applied Materials & Interfaces
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