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Research Proposal on stress

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https://www.readbyqxmd.com/read/29163862/comparison-of-dsm-5-and-proposed-icd-11-criteria-for-ptsd-with-dsm-iv-and-icd-10-changes-in-ptsd-prevalence-in-military-personnel
#1
Annika Kuester, Kai Köhler, Thomas Ehring, Christine Knaevelsrud, Louisa Kober, Antje Krüger-Gottschalk, Ingo Schäfer, Julia Schellong, Ulrich Wesemann, Heinrich Rau
Background: Recently, changes have been introduced to the diagnostic criteria for posttraumatic stress disorder (PTSD) according to the Diagnostic and Statistical Manual of Mental Disorders (DSM) and the International Classification of Diseases (ICD). Objectives:This study investigated the effect of the diagnostic changes made from DSM-IV to DSM-5 and from ICD-10 to the proposed ICD-11. The concordance of provisional PTSD prevalence between the diagnostic criteria was examined in a convenience sample of 100 members of the German Armed Forces...
2017: European Journal of Psychotraumatology
https://www.readbyqxmd.com/read/29163309/eye-movement-desensitization-and-reprocessing-and-slow-wave-sleep-a-putative-mechanism-of-action
#2
Marco Pagani, Benedikt L Amann, Ramon Landin-Romero, Sara Carletto
Eye Movement Desensitization and Reprocessing (EMDR) is considered highly efficacious for the treatment of Post-traumatic Stress Disorder and has proved to be a valid treatment approach with a wide range of applications. However, EMDR's mechanisms of action is not yet fully understood. This is an active area of clinical and neurophysiological research, and several different hypotheses have been proposed. This paper discusses a conjecture which focuses on the similarity between the delta waves recorded by electroencephalography during Slow Wave Sleep (SWS) and those registered upon typical EMDR bilateral stimulation (eye movements or alternate tapping) during recurrent distressing memories of an emotionally traumatic event...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/29161707/a-novel-animal-model-simulating-the-beginning-of-combat-exposure
#3
Dongsoo Kim, Chang Yul Kim, Hyojin Koo, Yong Heo, Kicheol Cheon
OBJECTIVE: Predator stress, social defeat stress, and fear conditioning animal models have been applied to investigate combat-related posttraumatic stress disorder (PTSD). However, no animal model psychopharmacological studies have investigated prevention of somatization of increased mental stress and fatigue at the beginning of combat exposure. This study utilized a novel animal model simulating the beginning of combat exposure that aided specification of a set of biomarkers. METHODS: Psychological stress was induced by both inescapable electric foot shock and noise stimuli...
November 22, 2017: Neuroimmunomodulation
https://www.readbyqxmd.com/read/29154641/do-the-antecedents-and-consequences-of-loneliness-change-from-middle-adulthood-into-old-age
#4
Anne Böger, Oliver Huxhold
Loneliness is a stressful experience that appears to interfere with health and social integration (SI). Recently, researchers proposed that both antecedents and consequences of loneliness may change across the life span. To fully understand the processes related to loneliness it may thus be crucial to adopt an age-differentiated perspective. This study contributes to the literature by investigating how the interrelationship between loneliness and SI and that between loneliness and physical health changes as people move from middle adulthood into old age...
November 20, 2017: Developmental Psychology
https://www.readbyqxmd.com/read/29154569/the-social-transmission-of-risk-maternal-stress-physiology-synchronous-parenting-and-well-being-mediate-the-effects-of-war-exposure-on-child-psychopathology
#5
Galit Halevi, Amir Djalovski, Yaniv Kanat-Maymon, Karen Yirmiya, Orna Zagoory-Sharon, Lee Koren, Ruth Feldman
While chronic early stress increases child susceptibility to psychopathology, risk and resilience trajectories are shaped by maternal social influences whose role requires much further research in longitudinal studies. We examined the social transmission of risk by assessing paths leading from war-exposure to child symptoms as mediated by 3 sources of maternal social influence; stress physiology, synchronous parenting, and psychiatric disorder. Mothers and children living in a zone of continuous war were assessed in early childhood (1...
November 2017: Journal of Abnormal Psychology
https://www.readbyqxmd.com/read/29150271/xenohormesis-in-early-life-new-avenues-of-research-to-explore-anti-aging-strategies-through-the-maternal-diet
#6
Philippe de Medina
Aging is a progressive internal physiological deterioration of the organism, leading to the occurrence of age-related lethal diseases. It has become a major societal challenge to understand the processes that drive aging and to develop rational pharmacological agents and dietary approaches to fight against age-related deterioration and diseases. Interestingly, several lines of evidence highlight an influence of the developmental period on the risk of age-related diseases later in life. This field is known as the developmental origins of health and disease...
November 2017: Medical Hypotheses
https://www.readbyqxmd.com/read/29147464/treatment-of-the-fluoroquinolone-associated-disability-the-pathobiochemical-implications
#7
REVIEW
Krzysztof Michalak, Aleksandra Sobolewska-Włodarczyk, Marcin Włodarczyk, Justyna Sobolewska, Piotr Woźniak, Bogusław Sobolewski
Long-term fluoroquinolone-associated disability (FQAD) after fluoroquinolone (FQ) antibiotic therapy appears in recent years as a significant medical and social problem, because patients suffer for many years after prescribed antimicrobial FQ treatment from tiredness, concentration problems, neuropathies, tendinopathies, and other symptoms. The knowledge about the molecular activity of FQs in the cells remains unclear in many details. The effective treatment of this chronic state remains difficult and not effective...
2017: Oxidative Medicine and Cellular Longevity
https://www.readbyqxmd.com/read/29145500/estimation-of-stress-distribution-in-ferromagnetic-tensile-specimens-using-low-cost-eddy-current-stress-measurement-system-and-bp-neural-network
#8
Jianwei Li, Weimin Zhang, Weiqin Zeng, Guolong Chen, Zhongchao Qiu, Xinyuan Cao, Xuanyi Gao
Estimation of the stress distribution in ferromagnetic components is very important for evaluating the working status of mechanical equipment and implementing preventive maintenance. Eddy current testing technology is a promising method in this field because of its advantages of safety, no need of coupling agent, etc. In order to reduce the cost of eddy current stress measurement system, and obtain the stress distribution in ferromagnetic materials without scanning, a low cost eddy current stress measurement system based on Archimedes spiral planar coil was established, and a method based on BP neural network to obtain the stress distribution using the stress of several discrete test points was proposed...
2017: PloS One
https://www.readbyqxmd.com/read/29130314/determining-psychoneuroimmunologic-markers-of-yoga-as-an-intervention-for-persons-diagnosed-with-ptsd-a-systematic-review
#9
Ursula Ann Kelly, Dian Dowling Evans, Helen Baker, Jessica Noggle Taylor
There is a growing body of research on yoga as a therapeutic intervention for psychological symptoms of post-traumatic stress disorder (PTSD) accompanied by speculations on underlying physiologic mechanisms. The purpose of this systematic review is to identify, qualitatively evaluate, and synthesize studies of yoga as an intervention for PTSD that measured physiologic outcomes in order to gain insights into potential mechanisms. The focus is on studies evaluating yoga as a therapeutic intervention for PTSD rather than for trauma exposure, PTSD prevention, or subclinical PTSD...
January 1, 2017: Biological Research for Nursing
https://www.readbyqxmd.com/read/29126911/why-mdma-therapy-for-alcohol-use-disorder-and-why-now
#10
REVIEW
Ben Sessa
Alcohol use disorder represents a serious clinical, social and personal burden on its sufferers and a significant financial strain on society. Current treatments, both psychological and pharmacological are poor, with high rates of relapse after medical detoxification and dedicated treatment programs. The earliest historical roots of psychedelic drug-assisted psychotherapy in the 1950s were associated with Lysergic acid diethylamide (LSD)-assisted psychotherapy to treat what was then called, alcoholism. But results were varied and psychedelic therapy with LSD and other 'classical' psychedelics fell out of favour in the wake of socio-political pressures and cultural changes...
November 7, 2017: Neuropharmacology
https://www.readbyqxmd.com/read/29124548/development-of-an-experimental-and-digital-cardiovascular-arterial-model-for-transient-hemodynamic-and-postural-change-studies-a-preliminary-framework-analysis
#11
Rodward L Hewlin, John P Kizito
The ultimate goal of the present work is to aid in the development of tools to assist in the treatment of cardiovascular disease. Gaining an understanding of hemodynamic parameters for medical implants allow clinicians to have some patient-specific proposals for intervention planning. In the present work an experimental and digital computational fluid dynamics (CFD) arterial model consisting of a number of major arteries (aorta, carotid bifurcation, cranial, femoral, jejunal, and subclavian arteries) were fabricated to study: (1) the effects of local hemodynamics (flow parameters) on global hemodynamics (2) the effects of transition from bedrest to upright position (postural change) on hemodynamics, and (3) diffusion of dye (medical drug diffusion simulation) in the arterial system via experimental and numerical techniques...
November 9, 2017: Cardiovascular Engineering and Technology
https://www.readbyqxmd.com/read/29121913/predicting-health-related-quality-of-life-in-cancer-patients-receiving-chemotherapy-a-structural-equation-approach-using-the-self-control-model
#12
Yu-Ri Park, Eun-Young Park, Jung-Hee Kim
BACKGROUND: According to the self-control model, self-control works as a protective factor and a psychological resource. Although an understanding of the effect(s) of peripheral neuropathy on quality of life is important to healthcare professionals, previous studies do not facilitate broad comprehension in this regard. The purpose of this cross-sectional study was to test the multidimensional assumptions of quality of life of patients with cancer, with focus on their self-control. METHODS: A structural equation model was tested on patients with cancer at the oncology clinic of a university hospital where patients received chemotherapy...
November 9, 2017: BMC Health Services Research
https://www.readbyqxmd.com/read/29120752/the-glycogen-shunt-maintains-glycolytic-homeostasis-and-the-warburg-effect-in-cancer
#13
REVIEW
Robert G Shulman, Douglas L Rothman
Despite many decades of study there is a lack of a quantitative explanation for the Warburg effect in cancer. We propose that the glycogen shunt, a pathway recently shown to be critical for cancer cell survival, may explain the excess lactate generation under aerobic conditions characteristic of the Warburg effect. The proposal is based on research on yeast and mammalian muscle and brain that demonstrates that the glycogen shunt functions to maintain homeostasis of glycolytic intermediates and ATP during large shifts in glucose supply or demand...
November 2017: Trends in Cancer
https://www.readbyqxmd.com/read/29114555/effectiveness-of-mindfulness-based-stress-reduction-on-emotion-regulation-and-test-anxiety-in-female-high-school-students
#14
Shokooh Shahidi, Hossein Akbari, Fatemeh Zargar
BACKGROUND: Test anxiety is one of the most disabling disorders and annual school academic performance will affect millions of students. Hence, it needs attention and treatment. Therefore, this research aimed to examine the effectiveness of a mindfulness-based stress reduction (MBSR) therapy on emotion regulation and test anxiety of students and test the remaining effect of this treatment after 3 month. METHODS: Sample size of fifty participants randomly divided into experimental (MBSR) and control groups...
2017: Journal of Education and Health Promotion
https://www.readbyqxmd.com/read/29111420/viscoelastic-shear-lag-model-to-predict-the-micromechanical-behavior-of-tendon-under-dynamic-tensile-loading
#15
Jiayu Wu, Hong Yuan, Longyuan Li, Kunjie Fan, Shanguang Qian, Bing Li
Owing to its viscoelastic nature, tendon exhibits stress rate-dependent breaking and stiffness function. A Kelvin-Voigt viscoelastic shear lag model is proposed to illustrate the micromechanical behavior of the tendon under dynamic tensile conditions. Theoretical closed-form expressions are derived to predict the deformation and stress transfer between fibrils and interfibrillar matrix while tendon is dynamically stretched. The results from the analytical solutions demonstrate that how the fibril overlap length and fibril volume fraction affect the stress transfer and mechanical properties of tendon...
October 27, 2017: Journal of Theoretical Biology
https://www.readbyqxmd.com/read/29107398/the-stress-reward-mentalizing-model-of-depression-an-integrative-developmental-cascade-approach-to-child-and-adolescent-depressive-disorder-based-on-the-research-domain-criteria-rdoc-approach
#16
REVIEW
Patrick Luyten, Peter Fonagy
The Research Domain Criteria (RDoC) propose a much-needed change in approach to the study of vulnerability factors implicated in mental disorders, shifting away from a categorical, disease-oriented model to a dimensional approach that focuses on underlying systems implicated in psychopathology. In this paper we illustrate this approach with a focus on the emergence of depression in childhood and adolescence. Based on evolutionary biological and developmental psychopathology considerations, we present an integrative developmental cascade model of depression that essentially suggests that depression emerges out of a three-pronged series of interacting impairments in the domains of stress regulation, reward, and mentalizing...
October 9, 2017: Clinical Psychology Review
https://www.readbyqxmd.com/read/29092019/transcriptional-analysis-of-impacts-of-glycerol-transporter-1-on-methanol-and-glycerol-metabolism-in-pichia-pastoris
#17
Xiang Li, Yankun Yang, Chunjun Zhan, Zhenyang Zhang, Xiuxia Liu, Hebin Liu, Zhonghu Bai
The efficient promoter of alcohol oxidase 1 (PAOX1) in methylotrophic yeast Pichia pastoris is strictly induced by methanol but repressed by glycerol with an unclear molecular mechanism. In the present study, the gene of a previously characterized transmembrane protein glycerol transporter 1 (GT1) of P. pastoris GS115 was deleted by homologous recombination. Transcriptional profiles of the mutant (gt1△) and wild-type (WT) were compared with different carbon sources (glycerol, methanol, and glycerol-methanol mix) at various time points using high-throughput RNA-Seq techniques...
October 30, 2017: FEMS Yeast Research
https://www.readbyqxmd.com/read/29075221/a-review-of-consequences-of-poverty-on-economic-decision-making-a-hypothesized-model-of-a-cognitive-mechanism
#18
REVIEW
Matúš Adamkovič, Marcel Martončik
This review focuses on the issue of poverty affecting economic decision-making. By critically evaluating existing studies, the authors propose a structural model detailing the cognitive mechanism involved in how poverty negatively impacts economic decision-making, and explores evidence supporting the basis for the formation of this model. The suggested mechanism consists of a relationship between poverty and four other factors: (1) cognitive load (e.g., experiencing negative affect and stress); (2) executive functions (e...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/29074230/a-novel-differential-susceptibility-framework-for-the-study-of-nightmares-evidence-for-trait-sensory-processing-sensitivity
#19
REVIEW
Michelle Carr, Tore Nielsen
Research on nightmares has largely focused on the nightmare itself and its associated negative consequences, framing nightmare sufferers as victims of a diathesis-stress induced form of psychopathology. However, there is evidence that frequent nightmare recallers are sensitive to a wide range of sensory and emotional experiences, and report vivid, bizarre and even intensely positive dream and daydream experiences. We propose sensory processing sensitivity as a novel trait marker that underlies the unique symptoms and imaginative richness found in nightmare-prone individuals...
December 2017: Clinical Psychology Review
https://www.readbyqxmd.com/read/29072367/reappraisal-of-metallothionein-clinical-implications-for-patients-with-diabetes-mellitus
#20
REVIEW
Yongsoo Park, Jian Zhang, Lu Cai
Reactive oxygen and nitrogen species (ROS/RNS) are by-products of cellular physiological processes made from the metabolisms of intermediary nutrients. Although physiological defense mechanisms readily convert these species into water or urea, improper balance between their production and removal leads cells to experience oxidative stress (OS), which is harmful to cellular components. This may result in uncontrolled growth or ultimately to cell death. ROS/RNS are also closely related to the development of diabetes and its complications...
October 26, 2017: Journal of Diabetes
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