keyword
MENU ▼
Read by QxMD icon Read
search

Kcot

keyword
https://www.readbyqxmd.com/read/29892529/quantitative-analysis-of-argyrophilic-nucleolar-organizer-regions-in-odontogenic-cysts-and-tumor-a-comparative-study
#1
Bhavana Gupta, Shaleen Chandra, Vineet Raj, Vivek Gupta
Background: The nucleolar organizer region (NOR) is by definition part of a chromosome, and nucleolus is a structure containing this chromosomal part and in addition the material which accumulate around the NOR, mostly rRNAs and their precursors as well as specific ribosomal proteins. Argyrophilic Nucleolar organizing region (AgNOR) are silver binding NORs often used to study cell proliferation in various types of tumors. Aim: Quantitative assessment of Argyrophilic Nucleolar organizing region count and its comparison among dentigerous cyst, keratocystic odontogenic tumor and ameloblastoma...
May 2018: Journal of Oral Biology and Craniofacial Research
https://www.readbyqxmd.com/read/29491624/trigeminal-neuralgia-induced-by-odontogenic-keratocyst-associated-with-impacted-supernumerary-teeth-a-rare-case-report
#2
Annaji Araleri Gopalkrishna, B N Tejasree, M Manjunath, D P Ashwin
Odontogenic keratocyst(OKC)is a cyst oftooth origin with an aggressive behavior including a high recurrence rate, it has been rechristened to keratocystic odontogenic tumor(KCOT) as it be the reflects its neoplastic nature. We report a case of KCOT in association with an impacted supernumerary tooth along with Trigeminal Neuralgia, that subsided by itself after removal of the cyst.
January 2018: Journal of Oral and Maxillofacial Pathology: JOMFP
https://www.readbyqxmd.com/read/29391730/odontogenic-tumors-review-of-127-cases-in-marathwada-region-of-maharashtra
#3
Atul Bhagwat, S R Barpande, J D Bhavthankar, M S Mandale, Jayanti Humbe, Preeti Singh
Introduction: Odontogenic tumors (OTs) are a group of heterogeneous lesions derived from epithelial or ectomesenchymal tissues or both, which are part of the tooth-forming apparatus. They range from hamartomatous or nonneoplastic tissue proliferations to malignant neoplasms with metastatic capacity. OTs are comparatively rare, comprising about 4.79% of all oral and maxillofacial biopsy specimens diagnosed. Several retrospective studies carried out in Africa, Asia, Europe and America, show that differences exist in the relative frequency of the various histologic types...
September 2017: Journal of Oral and Maxillofacial Pathology: JOMFP
https://www.readbyqxmd.com/read/29354003/diffusion-weighted-mr-imaging-of-unicystic-odontogenic-tumors-for-differentiation-of-unicystic-ameloblastomas-from-keratocystic-odontogenic-tumors
#4
Yifeng Han, Xindong Fan, Lixin Su, Zhenfeng Wang
Objective: Differentiating unicystic ameloblastomas from keratocystic odontogenic tumors (KCOT) is necessary for the planning of different treatment strategies; however, it is difficult based on conventional CT and MR sequences alone. The purpose of this study was to investigate the utility of diffusion-weighted imaging (DWI) and apparent diffusion coefficients (ADCs) in the differentiation of the two tumors. Materials and Methods: We prospectively studied 40 patients with odontogenic cysts and tumors of the maxillomandibular region using conventional MR imaging and DWI...
January 2018: Korean Journal of Radiology: Official Journal of the Korean Radiological Society
https://www.readbyqxmd.com/read/29298784/conservative-management-of-keratocystic-odontogenic-tumour-in-a-young-child-with-decompression-and-an-intraoral-appliance-5-year-follow-up
#5
Rahul Morankar, Sarabjot K Bhatia, Ashima Goyal, Pramod Gulia
Keratocystic odontogenic tumour (KCOT) is considered one of the most aggressive odontogenic lesions presenting high recurrence rate which varies according to treatment modalities employed for management. The treatment rendered should have a lowest possible risk of recurrence and least morbidity while still eradicating the lesion. Although the radical treatment options like enucleation and en bloc resection are associated with lesser recurrences, these can lead to greater morbidity, especially in children with developing teeth and jaw bones, thus, emphasising need to consider more conservative treatment options like decompression and marsupialisation...
January 3, 2018: BMJ Case Reports
https://www.readbyqxmd.com/read/29279565/the-effects-of-marsupialization-on-bone-regeneration-adjacent-to-keratocystic-odontogenic-tumors-and-the-mechanisms-involved
#6
Xiang Hu, Yi Zhao, Qi-Wen Man, Rui-Fang Li, Bing Liu, Yi-Fang Zhao
Bone resorption in the jaws is one of the most severe complications of keratocystic odontogenic tumors (KCOTs), and can be treated by either enucleation or marsupialization. However, the effects of marsupialization on bone regeneration adjacent to KCOTs, and the mechanisms involved, are still unclear. In this study, samples of 27 KCOTs were collected (20 before marsupialization and 7 after marsupialization) to detect the expression of bone regeneration-related molecules adjacent to KCOTs by immunohistochemistry and real-time quantitative polymerase chain reaction (qPCR)...
2017: Journal of Oral Science
https://www.readbyqxmd.com/read/29233700/volumetric-analysis-of-keratocystic-odontogenic-tumors-and-non-neoplastic-jaw-cysts-comparison-and-its-clinical-relevance
#7
Martin Kauke, Ali-Farid Safi, Andrea Grandoch, Hans-Joachim Nickenig, Joachim Zöller, Matthias Kreppel
The keratocystic odontogenic tumor (KCOT) is capable of causing vast osseous destruction. Histopathological examination is pivotal for diagnosis. The diagnostic process can sometimes be hindered by tissue inflammation of KCOTs with loss of defining criteria, resulting in misdiagnosis as an odontogenic jaw cyst. We discuss the possible merits of volumetric analysis when facing this particular diagnostic dilemma and for pathophysiological characterization of KCOTs. We included 114 patients, of whom 27 were histopathologically diagnosed with a KCOT and 87 with dentigerous (n = 41) and periapical cyst (n = 46)...
February 2018: Journal of Cranio-maxillo-facial Surgery
https://www.readbyqxmd.com/read/29199341/-expression-of-receptor-activator-of-nuclear-factor-%C3%AE%C2%BAb-ligand-in-keratocystic-odontogenic-tumor-before-and-after-decompression
#8
Bo Zhang, Wen-Cheng Ye, Ying Li, Xin-Mu Zhou, Yi-Ling Zhu
PURPOSE: To investigate the expression of receptor activator of nuclear factor-κB ligand (RANKL) in keratocystic odontogenic tumor (KCOT) before and after decompression. METHODS: Twenty two pairs of paraffin-embeded tissue specimens of KCOT were collected and subjected to immunohistochemical analysis of RANKL.The data were analyzed with SPSS17.0 software package for paired t test. RESULTS: RANKL positive cells were observed in the preoperative KCOT epithelium...
August 2017: Shanghai Kou Qiang Yi Xue, Shanghai Journal of Stomatology
https://www.readbyqxmd.com/read/29109321/epidemiological-and-clinicopathological-analysis-of-92-odontogenic-tumors-a-5-year-retrospective-study
#9
Ipsita Sharma, Deepa Venkatesh, Geetanjali Bawa, Syed Vaseemuddin, Amit Joseph, Jimmy K Sangtani
INTRODUCTION: Odontogenic tumors (OTs) are a heterogeneous group of lesions that are derived from odontogenic apparatus comprised of odontogenic epithelium, ectomesenchyme, and/ or mesenchymal elements. The OTs show marked geographical variation. This study was conducted to analyze the epidemiology and clinicopathological presentation of OTs based on age, sex, and site. MATERIALS AND METHODS: This study was conducted in Department of Oral Pathology and Microbiology...
November 1, 2017: Journal of Contemporary Dental Practice
https://www.readbyqxmd.com/read/29103753/frequent-oncogenic-braf-v600e-mutation-in-odontogenic-keratocyst
#10
Yong Hoon Cha, Eunae Sandra Cho, Hee Eun Kang, Jaemin Ko, Woong Nam, Hyung Jun Kim, Nam Hee Kim, Hyun Sil Kim, In-Ho Cha, Jong In Yook
OBJECTIVES: Odontogenic keratocyst (OKC), also known as keratocystic odontogenic tumor (KCOT), has clinical significance due to its high incidence as well as high recurrence rate after surgical enucleation. Current clinical management for OCK is entirely dependent on surgical approach. While various genetic alterations, such as PTCH1 mutation and loss of heterozygosity in tumor suppressor genes, have been reported, the molecular background of OKC is not well-understood. Although recent identification of BRAF V600E mutation and subsequent activation of mitogen-activated protein kinase (MAPK) pathway in ameloblastoma and odontogenic tumors provide additional options with targeted therapeutics, the molecular background of OKC is not well understood...
November 2017: Oral Oncology
https://www.readbyqxmd.com/read/29039452/molecular-analysis-of-keratocystic-odontogenic-tumor-cell-lines-derived-from-sporadic-and-basal-cell-nevus-syndrome-patients
#11
Kazuma Noguchi, Keiko Wakai, Tohru Kiyono, Mutsuki Kawabe, Kyohei Yoshikawa, Tomoko Hashimoto-Tamaoki, Hiromitsu Kishimoto, Yoshiro Nakano
Keratocystic odontogenic tumor (KCOT) is a benign tumor often associated with basal cell nevus syndrome (BCNS). Mutations in Patched 1 (PTCH1), the Hedgehog (Hh) receptor, are responsible for BCNS. BCNS is distinguished by morphological anomalies and predisposition to benign and malignant tumors, including medulloblastoma, basal cell carcinoma, KCOT and ovarian fibromas. Among these tumors, KCOT is the least well studied because a suitable model system is not available for its investigation. To enable KCOT to be studied, we established two KCOT cell lines, one from a BCNS case (designated as iKCOT1) and one from a sporadic KCOT case (designated as sKCOT1)...
October 9, 2017: International Journal of Oncology
https://www.readbyqxmd.com/read/28969743/ortho-keratinized-odontogenic-cyst-with-dentinoid-formation
#12
Manas Bajpai, Nilesh Pardhe, Manika Aroroa, Betina Chandolia
Orthokeratinized odontogenic keratocyst (OOC) was first identified as orthokeratinized variant of odontogenic keratocyst in 1981 by Wright, due to its different histology and relatively low recurrence rate. Parakeratinized odontogenic cyst is now considered as keratocystic odontogenic tumor (KCOT) owing to its neoplastic nature. Although rare, calcification in the form of dystrophic calcification, dentinoid and cartilage has been reported in KCOT, but calcification in OOC is extremely rare and no case in English literature has been reported so far...
September 2017: Journal of the College of Physicians and Surgeons—Pakistan: JCPSP
https://www.readbyqxmd.com/read/28862228/a-study-of-the-distribution-of-b-cell-lymphoma-leukemia-2-in-odontogenic-cyst-and-tumors-histochemical-study
#13
Khushboo Phull, Rashmi Metgud, Shrikant Patel
INTRODUCTION: The odontogenic keratocyst is known for its aggressiveness, high recurrence rate, and transformation of keratinized epithelia to nonkeratinized squamous epithelium for which inflammation has been suggested to be responsible. B-cell lymphoma/leukemia-2 (Bcl-2) an anti-apoptotic protein, prolongs the life span of epithelial cells and allows proliferation, differentiation, and morphogenesis. MATERIALS AND METHODS: Study was carried out comprising of 90 cases; (30 ameloblastoma, 30 keratocystic odontogenic tumor (KCOT), and 30 radicular cyst)...
July 2017: Journal of Cancer Research and Therapeutics
https://www.readbyqxmd.com/read/28761280/recurrent-keratocystic-odontogenic-tumor-of-right-maxillary-sinus-involving-the-right-infraorbital-rim
#14
Karthikeyan Maruthamuthu, G Vasupradha, Janardhanam Dineshshankar, Abishek Rajaram Balaji
Keratocystic odontogenic tumor (KCOT) is a benign odontogenic tumor with an aggressive behavior and high recurrence rate. The most common site of predilection is the posterior mandible. In contrast, KCOTs occurring in the maxillary region are relatively rare. However, the maxillary involvement poses a greater and increased threat, due to proximity to vital structures such as maxillary sinus, orbital floor, and infratemporal fossa. This report presents such a case of KCOT involving the maxillary sinus eroding the floor of the orbit and provides an account of the factors that need to be considered during management...
January 2017: National Journal of Maxillofacial Surgery
https://www.readbyqxmd.com/read/28706783/the-anecdote-of-viral-etiopathogenia-in-ameloblastoma-and-odontogenic-keratocyst-why-don-t-we-let-it-go
#15
Bacem A E O Khalele
BACKGROUND: Ameloblastoma (AM) and odontogenic Keratocyst (OKC) are destructive odontogenic lesions of the gnathion. Although their exact pathogeneses are not yet totally understood, the viral etiopathogenesis in AM and KCOT has been proposed. True to syndromic keratocystic odontogenic tumor (sKCOT) and non-syndromic OKC is the high recurrence rate. OBJECTIVES: Given that shared pathways trailed by AM and by sKCOT/OKC have been suggested, this study, however, contrasts the expression of AM and OKC for viral antibodies...
May 2017: Journal of Oral Biology and Craniofacial Research
https://www.readbyqxmd.com/read/28706782/immunohistochemical-evaluation-of-podoplanin-in-odontogenic-tumours-cysts-using-anti-human-podoplanin-antibody
#16
Namrata Singhal, Nitin Khanduri, Deepak Kurup, Brijesh Gupta, Pranjan Mitra, Roshani Chawla
BACKGROUND: Odontogenic Cysts & tumors originate through some aberration from the normal pattern of odontogenesis. Ameloblastoma is one of the most frequent intraosseous odontogenic tumors. However it is no longer appropriate to use the diagnosis of ameloblastoma without specifying the type. Varied-clinical entities of ameloblastoma differ in their biologic behaviour. Odontogenic cysts like dentigerous and radicular cysts are less aggressive in nature than odontogenic tumors. Recently, podoplanin commonly used as a lymphatic endothelial marker in cancers has recently been found to play a possible role in odontogenic tumorigenesis also...
May 2017: Journal of Oral Biology and Craniofacial Research
https://www.readbyqxmd.com/read/28700034/application-of-endoscopy-to-treat-mandibular-keratocystic-odontogenic-tumors
#17
Z Gao, Q W Ni, W Gao, Y P Liu, Q Zhang
The aim of this study was to evaluate the feasibility of endoscopy to remove keratocystic odontogenic tumors (KCOTs) with virtual 3D mandibular images. Fifteen patients (mean age, 40.27±14.58 years) who underwent endoscopic mandibular KCOT enucleation between May 2009 and October 2009 were included. Virtual 3D mandibular reconstructions derived from computed tomography (CT) imaging were generated for all patients. Recurrence and pathological fracture were evaluated as the primary outcome variables at 1 and 12 months after operation...
July 10, 2017: Brazilian Journal of Medical and Biological Research, Revista Brasileira de Pesquisas Médicas e Biológicas
https://www.readbyqxmd.com/read/28688493/computer-aided-diagnosis-of-periapical-cyst-and-keratocystic-odontogenic-tumor-on-cone-beam-computed-tomography
#18
E Yilmaz, T Kayikcioglu, S Kayipmaz
BACKGROUND AND OBJECTIVES: In this article, we propose a decision support system for effective classification of dental periapical cyst and keratocystic odontogenic tumor (KCOT) lesions obtained via cone beam computed tomography (CBCT). CBCT has been effectively used in recent years for diagnosing dental pathologies and determining their boundaries and content. Unlike other imaging techniques, CBCT provides detailed and distinctive information about the pathologies by enabling a three-dimensional (3D) image of the region to be displayed...
July 2017: Computer Methods and Programs in Biomedicine
https://www.readbyqxmd.com/read/28650783/conservative-treatment-of-multiple-keratocystic-odontogenic-tumors-in-a-young-patient-with-nevoid-basal-cell-carcinoma-syndrome-by-decompression-a-7-year-follow-up-study
#19
Su-Hyun Kim, Min-Seok Oh, Yo-Seob Seo, Jin-Young Kim, Soon-Hyeun Nam, Su-Min Lim
Multiple keratocystic odontogenic tumors (KCOT) occurred in a young child is challenging problem in the field of pediatric dentistry, and might have been related to nevoid basal cell carcinoma syndrome (NBCCS). Because of high recurrence rate of KCOTs, complete surgical resection is generally accepted as definitive treatment. However, complete surgical resection could induce negative effect on the development of permanent teeth and growth of jaw. Herein, we reported successful treatment case of young KCOT patient with NBCCS...
2017: Journal of Clinical Pediatric Dentistry
https://www.readbyqxmd.com/read/28628158/-effects-of-ptch1-mutations-on-the-epithelial-proliferation-derived-from-keratocystic-odontogenic-tumour
#20
(no author information available yet)
OBJECTIVE: To explore the relationship between the PTCH1 mutation and the expression of bcl-2, filaggrin, and loricrin in the keratocystic odontogenic tumour (KCOT), as well as the effects of the mutated PTCH1 on the epithelial proliferation and differentiation. METHODS: The samples were collected from 20 cases of KCOT with mutated PTCH1, as well as 20 cases without mutation. All the samples were analyzed with immunohistochemical staining, for the purpose of investigating the expression of bcl-2, filaggrin, and loricrin...
June 18, 2017: Beijing da Xue Xue Bao. Yi Xue Ban, Journal of Peking University. Health Sciences
keyword
keyword
55163
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"