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https://www.readbyqxmd.com/read/28060370/diagnosing-the-most-common-odontogenic-cystic-and-osseous-lesions-of-the-jaws-for-the-practicing-pathologist
#1
Robert A Robinson
Odontogenic cysts and osseous lesions are often seen as challenging diagnostic lesions but the majority of them are easily classified. This article outlines the diagnostic features required for separating the most common of odontogenic cysts and select osseous lesions of the jaws. Clinical and radiographic findings of these jaw lesions often lead to a differential diagnosis that only the histologic findings will clarify. Dentigerous cyst, keratocystic odontogenic tumor, and certain ameloblastomas that have cystic change, may have identical radiographic findings, with only separation by their specific histologic features leading to the significantly different treatments required for each...
January 2017: Modern Pathology: An Official Journal of the United States and Canadian Academy of Pathology, Inc
https://www.readbyqxmd.com/read/28054463/kallikrein-related-peptidase-expression-in-odontogenic-cysts-and-tumors-an-immunohistochemical-comparative-study
#2
Mark Roger Darling, Rebecca Woodford, Karl Kevin Cuddy, Linda Jackson-Boeters, Alyssa Hayter, Jeyanth Inkaran, Eleftherios P Diamandis, Zia Khan
AIM: The aim of the present study was to profile the expression of human kallikrein (KLK)-related peptidases (KLK) in odontogenic lesions. METHODS: Paraffin-embedded, formalin-fixed, non-odontogenic (control) and odontogenic lesions were stained for KLK using a standard immunohistochemical technique. The intensity and proportion of epithelial cells stained was scored. Reverse transcription-polymerase chain reaction was utilized to evaluate KLK 1-15 mRNA expression in ameloblastomas...
January 4, 2017: Journal of Investigative and Clinical Dentistry
https://www.readbyqxmd.com/read/28027172/an-uncommon-occurrence-of-three-fourth-molars-concomitant-to-hypodontia-in-a-nonsyndromic-patient
#3
Ligia Buloto Schmitd, Agnes Assao, Gabriel Ramalho-Ferreira, Leonardo Perez Faverani, Denise Tostes Oliveira
Bilaterally mandibular and maxillary fourth molars, concomitant to hypodontia, are uncommon. These dental anomalies, called hypohyperdontia, are rare and etiology is not well defined. Several complications may occur as a consequence of supernumerary teeth, such as teeth impaction, resorption of adjacent teeth, and development of cysts and tumors. The authors present an uncommon occurrence of three-fourth molars concomitant to hypodontia and dentigerous cyst associated with impacted mandibular second and third molars in a nonsyndromic patient...
December 23, 2016: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/28025428/expression-of-p73-and-trail-in-odontogenic-cysts-and-tumors
#4
Marco Mascitti, Andrea Santarelli, Antonio Zizzi, Maurizio Procaccini, Lorenzo Lo Muzio, Corrado Rubini
Odontogenic tumors are a group of lesions arising from the odontogenic apparatus. Although the mechanism of oncogenesis and tumor progression in these lesions remains unknown, certain proteins, such as those involved in apoptosis, seem to be involved in the differentiation and proliferation of odontogenic epithelial cells. The aim of this study was to analyze the expression of p73 and TNF-related apoptosis-inducing ligand (TRAIL) in odontogenic tumors and cysts, and to clarify changes in the expression of these proteins...
2016: Journal of Oral Science
https://www.readbyqxmd.com/read/27974959/a-10-year-retrospective-analysis-of-64-cases-of-cystic-lesions-of-the-oral-and-maxillofacial-region-in-a-nigerian-tertiary-hospital
#5
Benjamin Fomete, Otasowie Daniel Osunde, Joseph Ogbeifun, Rowland Agbara, Charles Ndubissi Ononiwu
OBJECTIVES: Orofacial cysts are broadly divided into odontogenic and nonodontogenic types, epithelial or non-epithelial, and developmental or inflammatory in origin. The odontogenic cyst is an osseous-destructive lesion that most commonly affects the jaw. It is formed by activation of odontogenic cell rests entrapped within the bone or gingival tissue of the jaws, such as the epithelial remains of Malassez, the dental lamina (cell rests of Serres), or the enamel organ. METHODS: We performed a retrospective study of all histologically diagnosed cysts of the orofacial region seen at the Maxillofacial clinic of the Ahmadu Bello University Teaching Hospital, Nigeria, between January 2003 and December 2012...
November 2016: Oman Medical Journal
https://www.readbyqxmd.com/read/27941544/large-dentigerous-cyst-associated-to-maxillary-canine
#6
João Paulo Bonardi, Pedro Henrique Silva Gomes-Ferreira, Leonardo de Freitas Silva, Gustavo Antonio Correa Momesso, Danila de Oliveira, Sabrina Ferreira, Rodrigo Dos Santos Pereira, Francisley Ávila Souza
Dentigerous cysts are defined as a cyst originated by separation of the follicle of dental crown of a tooth unerupted. Although most dentigerous cysts are considered developmental cysts, some cases seem to have an inflammatory origin. The aim of this study was to show a case of an 8-year-old patient, male, presenting a lesion in maxilla with large proportions. Computed tomography scans showed a hypodense image, well-defined, associated to unerupted teeth. The case was treated by enucleation of the lesion under local anesthesia...
December 8, 2016: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/27935113/fak-is-overexpressed-in-keratocystic-odontogenic-tumor-a-preliminary-study
#7
Sachin C Sarode, Gargi S Sarode, Shakira Choudhary, Shankargouda Patil
BACKGROUND: Focal adhesion kinase (FAK) is an important mediator of cell adhesion, growth proliferation, survival, angiogenesis, and migration. FAK is over expressed in many locally invasive and malignant lesions including oral cancer. Looking at the tumorigenic nature of keratocystic odontogenic tumor (KCOT), which involves local invasion, proliferation, and recurrence, we hypothesized strong expression of FAK in the epithelial lining of KCOT. MATERIALS AND METHODS: 34 KCOTs, 11 orthokeratinized odontogenic cysts (OOCs), 25 radicular cysts (RCs), 17 dentigerous cysts (DCs) and 25 dental follicles (DFs) were retrieved from archives and subjected to the immunohistochemical analysis using FAK antibody...
December 9, 2016: Journal of Oral Pathology & Medicine
https://www.readbyqxmd.com/read/27923382/ectopic-third-molars-in-the-sigmoid-notch-etiology-diagnostic-imaging-and-treatment-options
#8
Marcel Hanisch, Leopold F Fröhlich, Johannes Kleinheinz
BACKGROUND: The etiology of ectopic third molars located in the sigmoid notch of the mandible is unclear. Only a few cases have been reported. The aim of this article is to discuss the etiology as well as treatment options and diagnostic imaging techniques. METHODS: A PubMed and Medline search of the literature from 1965 to 2015 to ectopic third molars in the mandibular notch was performed. Furthermore, a clinical case provided by the authors is reported. RESULTS: Among the eight reviewed cases, two male and six female patients were affected that ranged from 25 to 62 years of age (mean 48...
December 6, 2016: Head & Face Medicine
https://www.readbyqxmd.com/read/27882603/establishment-and-characterization-of-a-cell-population-derived-from-a-dentigerous-cyst
#9
Marcos A Muñiz-Lino, Mariana Rodríguez-Vázquez, Bibiana Chávez-Munguía, Josué Z Ortiz-García, Lorena González-López, Fidel C Hernández-Hernández, Carlos Licéaga-Escalera, Alejandro García-Muñoz, Mario A Rodríguez
BACKGROUND: Dentigerous cyst occurs in approximately 20% of jaw cysts, being the second major common odontogenic cyst, after radicular cyst. This oral lesion has the ability to destroy maxillary bones and could be the origin of several odontogenic tumors. However, molecules implicated in its pathogenesis as well as those involved in its neoplastic transformation remain unknown. Here, we established a cell population derived from a dentigerous cyst as an in vitro model for the study of this oral lesion...
November 24, 2016: Journal of Oral Pathology & Medicine
https://www.readbyqxmd.com/read/27857903/orthokeratinized-odontogenic-cyst-masquerading-as-dentigerous-cyst
#10
Devi Charan Shetty, Ajit Singh Rathore, Anshi Jain, Natasha Thokchom, Neha Khurana
The orthokeratinized odontogenic cyst (OOC) is a rare developmental odontogenic cyst that has been considered as a variant of the keratocystic odontogenic tumor until Wright (1981) defined it as a different entity. Recognition of OOC as a unique entity has long been due, yet its inexplicable clinical, radiographic presentation resembling dentigerous cyst due to its association to an impacted tooth, and its histological features makes it rather perplexing. This is the report of a case of OOC in relation to an impacted maxillary canine and its immunohistochemical analysis with Ki-67...
October 2016: International Journal of Applied and Basic Medical Research
https://www.readbyqxmd.com/read/27853924/retrospective-analysis-of-nonendodontic-periapical-lesions-misdiagnosed-as-endodontic-apical-periodontitis-lesions-in-a-population-of-taiwanese-patients
#11
Hsun-Yu Huang, Yuk-Kwan Chen, Edward Cheng-Chuan Ko, Fu-Hsiung Chuang, Ping-Ho Chen, Ching-Yi Chen, Wen-Chen Wang
OBJECTIVE: We aimed to evaluate nonendodontic periapical lesions clinically misdiagnosed as endodontic periapical pathoses in a population of Taiwanese patients. MATERIALS AND METHODS: Cases (2000-2014) of histopathological diagnoses of nonendodontic periapical lesions were retrieved from all cases with a clinical diagnosis of radicular cyst, apical granuloma, or apical periodontitis in the institution. These cases were regarded as misdiagnosed nonendodontic periapical lesions, of which the types and frequencies, in addition to the demographic data, were determined...
November 16, 2016: Clinical Oral Investigations
https://www.readbyqxmd.com/read/27849342/dentigerous-cyst-associated-with-ectopically-impacted-maxillary-second-premolar
#12
Sulabha An, Bhari Sharanesha Manjunatha, Madhusudan Astekar, Sameer C
Dentigerous cysts are benign odontogenic cysts that are accompanying with the crown of permanent teeth. They are typically single in incidence and are situated in the mandible. They are usually associated with impacted mandibular third molar and maxillary canines. Here we report a very rare presentation of dentigerous cyst in anterior maxilla accompanying with ectopically impacted maxillary second premolar. The cyst was enucleated along with extraction of premolar.
November 2016: Journal of Experimental Therapeutics & Oncology
https://www.readbyqxmd.com/read/27843264/mandibular-dentigerous-cyst-in-a-10-year-old-child
#13
Bindu Bhardwaj, Sunil Sharma, Punit Chitlangia, Prateek Agarwal, Amit Bhamboo, Komal Rastogi
: Dentigerous cyst is the most common odontogenic cyst. It is characterized by a unilocular radiolucent lesion that encloses permanent tooth buds or, under certain circumstances, displaced tooth buds. Buccal bony expansion and a missing tooth is the most common clinical feature. Various treatment modalities have been mentioned in the literature for management of dentigerous cysts. This article presents a left mandibular dentigerous cyst in a 10-year-old boy. Marsupialization was the treatment of choice and a denturelike space maintainer was provided...
July 2016: International Journal of Clinical Pediatric Dentistry
https://www.readbyqxmd.com/read/27818958/giant-keratocystic-odontogenic-tumor-a-challenging-diagnosis
#14
Rachna Kaushik, Kumar Pushpanshu, Silky Rajesh Punyani, Vineet Raj
The keratocystic odontogenic tumor, although a benign lesion, is peculiarly aggressive with a high recurrence rate. Its involvement with the maxillary antrum is atypical. We report the unusual case of a 20-year-old male patient with an extensive antral tumor associated with an impacted third molar, which was initially misdiagnosed as a dentigerous cyst. Clinical, radiographic, and histopathologic aspects were analyzed to provide useful information for the correct diagnosis, treatment, and prognosis within a multidisciplinary approach...
July 2016: Autopsy & case reports
https://www.readbyqxmd.com/read/27795861/value-of-magnetic-resonance-imaging-for-diagnosis-of-dentigerous-cyst
#15
Antonione Santos Bezerra Pinto, André Luiz Ferreira Costa, Neiandro Dos Santos Galvão, Thásia Luiz Dias Ferreira, Sérgio Lúcio Pereira de Castro Lopes
Odontogenic cysts have a high prevalence in the dental clinic population, with dentigerous cyst being one of the most frequent ones and whose aetiology involves accumulation of fluid between the reduced enamel epithelium and the crown of an unerupted tooth. In the diagnostic process of these lesions, one should consider complementary imaging exams such as conventional radiography and computed tomography, which are commonly used for providing anatomical information on the tissues compromised by the lesion, but not on the nature of it...
2016: Case Reports in Dentistry
https://www.readbyqxmd.com/read/27770472/whatsapp-is-an-effective-tool-for-obtaining-second-opinion-in-oral-pathology-practice
#16
Sachin C Sarode, Gargi S Sarode, Rahul Anand, Shankargouda Patil, Hemant Unadkat
BACKGROUND: The aim of this study was to find out the efficacy of WhatsApp application for obtaining second opinion on histopathological diagnosis in oral pathology practice. METHODS: A total of 247 cases comprising of 34 different oral pathologies were photomicrographed using smartphone cameras through compound microscopes and sent for second opinion diagnosis (SOD) to 20 different oral pathologists using WhatsApp. RESULTS: Of 4795 (97.06%) total second opinion received, correct SOD were received for 4710 (98...
October 22, 2016: Journal of Oral Pathology & Medicine
https://www.readbyqxmd.com/read/27756334/maxillary-unicystic-ameloblastoma-a-case-report
#17
Zana Agani, Vjosa Hamiti-Krasniqi, Jehona Recica, Mergime Prekazi Loxha, Fisnik Kurshumliu, Aida Rexhepi
BACKGROUND: Ameloblastoma is a benign epithelial odontogenic tumor. It is often aggressive and destructive, with the capacity to attain great size, erode bone and invade adjacent structures. Unicystic ameloblastoma is a rare odontogenic lesion, with clinical, radiographic and gross features of jaw cysts. The lesion histologically shows typical ameloblastomatous epithelium lining part of the cyst cavity with or without and/or mural tumor growth. Unicystic ameloblastoma usually presents in posterior mandibular ramus region, while it is rare and atypical in posterior maxillary region...
October 18, 2016: BMC Research Notes
https://www.readbyqxmd.com/read/27721599/expression-of-ck14-and-vimentin-in-adenomatoid-odontogenic-tumor-and-dentigerous-cyst
#18
Muniswamappa Sudhakara, S Puranik Rudrayya, Srineevas S Vanaki, RamanPreet Kaur Bhullar, M S Shivakumar, Mahadevi Hosur
BACKGROUND: Origin of adenomatoid odontogenic tumor (AOT) has long been a controversy, and the issue of it being a neoplasm or hamartoma was a subject of debate for a long time. Earlier it was grouped under a mixed group of odontogenic tumors considering the varying degrees of inductive changes. Recently, the WHO classification states that the presence of hard tissue within AOT was not due to induction but was rather a metaplastically produced mineralization and hence the tumor was reclassified under a group of tumors arising from odontogenic epithelium...
September 2016: Journal of Oral and Maxillofacial Pathology: JOMFP
https://www.readbyqxmd.com/read/27701342/a-revision-of-the-pseudotropheus-elongatus-species-group-teleostei-cichlidae-%C3%A2-with-description-of-a-new-genus-and-seven-new-species
#19
Shan Li, Adrianus F Konings, Jay R Jr Stauffer
Lake Malaŵi is known for its endemic haplochromine species flock, most notably the rock-dwelling cichlids known as mbuna. The group of mbuna referred to as the Pseudotropheus elongatus species group is currently comprised of Metriaclima spp., Tropheops spp., Cynotilapia spp., and Pseudotropheus spp. In this study, Chindongo, a new genus with the type species C. bellicosus, is described for additional species in this group. Chindongo is distinguished from other mbuna genera by 1) the presence of bicuspid teeth in the anterior portion of the outer row of both upper and lower jaw; 2) a moderately to steeply sloped vomer with a narrow rostral tip which makes an angle of between 53° and 68° with the parasphenoid; 3) a small mouth with the lower jaw slightly shorter than the upper; 4) a broad anterior dentigerous area on both premaxilla and dentary with three or more rows of teeth (usually 5-6 rows); 5) a flank melanin pattern consisting of vertical bars without horizontal elements at any stage of development...
September 15, 2016: Zootaxa
https://www.readbyqxmd.com/read/27672610/jaw-lesions-associated-with-impacted-tooth-a-radiographic-diagnostic-guide
#20
REVIEW
Hamed Mortazavi, Maryam Baharvand
This review article aimed to introduce a category of jaw lesions associated with impacted tooth. General search engines and specialized databases such as Google Scholar, PubMed, PubMed Central, MedLine Plus, Science Direct, Scopus, and well-recognized textbooks were used to find relevant studies using keywords such as "jaw lesion", "jaw disease", "impacted tooth", and "unerupted tooth". More than 250 articles were found, of which approximately 80 were broadly relevant to the topic. We ultimately included 47 articles that were closely related to the topic of interest...
September 2016: Imaging Science in Dentistry
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