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https://www.readbyqxmd.com/read/29779004/cancer-incidence-among-merchant-seafarers-an-extended-follow-up-of-a-danish-cohort
#1
Kajsa Ugelvig Petersen, Julie Volk, Linda Kaerlev, Henrik Lyngbeck Hansen, Johnni Hansen
OBJECTIVES: While maritime safety generally has improved dramatically over the last century, modern seafarers are still faced with numerous occupational hazards potentially affecting their risk of chronic diseases such as cancer. The aim of this study is to offer updated information on the incidence of specific cancers among both male and female seafarers. METHODS: Using records from the Danish Seafarer Registry, all seafarers employed on Danish ships during 1986-1999 were identified, resulting in a cohort of 33 084 men and 11 209 women...
May 19, 2018: Occupational and Environmental Medicine
https://www.readbyqxmd.com/read/29777039/time-dependent-effect-of-intensity-of-smoking-and-of-occupational-exposure-to-asbestos-on-the-risk-of-lung-cancer-results-from-the-icare-case-control-study
#2
Emilie Lévêque, Aude Lacourt, Danièle Luce, Marie-Pierre Sylvestre, Pascal Guénel, Isabelle Stücker, Karen Leffondré
OBJECTIVE: To estimate the impact of intensity of both smoking and occupational exposure to asbestos on the risk of lung cancer throughout the whole exposure history. METHODS: Data on 2026 male cases and 2610 male controls came from the French ICARE (Investigation of occupational and environmental causes of respiratory cancers) population-based, case-control study. Lifetime smoking history and occupational history were collected from standardised questionnaires and face-to-face interviews...
May 18, 2018: Occupational and Environmental Medicine
https://www.readbyqxmd.com/read/29775975/misleading-new-insights-into-the-chrysotile-debate
#3
H-J Woitowitz, X Baur
Although there is no dispute among independent scientists about the carcinogenic and fibrogenic effects of chrysotile, the asbestos industry has been continuously and successfully acting to cast doubts on its harm. Another approach including asbestos insurance entities is to refuse compensation by raising the bar and fight criminal prosecution for asbestos-related diseases by the help of paid scientists. A recent publication on asbestos fibre burden in human lungs fits well in this context. The claim that chrysotile fibres are biopersistent in human lung is not based on the data provided by these authors, and, additionally, exhibits serious inconsistencies and obvious mismeasurements and significant methodological problems...
May 18, 2018: Pneumologie
https://www.readbyqxmd.com/read/29775648/towards-a-quantitative-model-to-predict-the-toxicity-pathogenicity-potential-of-mineral-fibers
#4
Alessandro F Gualtieri
A number of mineral fibers represent a health hazard because they are classified as cancer-causing chemical/physical toxicants upon (chronic) dust inhalation. Although in the last decades they have been the subject of intensive multidisciplinary investigations, the mechanisms by which mineral fibers induce toxic and pathogenic adverse effects on human health and environment are not yet fully understood. The major intricacy of the biological approach that prevents the design of a conclusive shared model of behavior of mineral fibers in a biological system stems from their very nature with intrinsic variability in chemical, molecular, structural and morphometric parameters, biodurability and surface reactivity...
May 15, 2018: Toxicology and Applied Pharmacology
https://www.readbyqxmd.com/read/29774715/-health-surveillance-programme-for-workers-with-past-asbestos-exposure-in-tuscany-region-central-italy
#5
Elisabetta Chellini, Francesca Battisti, Maura Pellegri, Maurizio Baldacci, Domenico Sallese, Alfonso Cristaudo, Pietro Sartorelli, Giulio Arcangeli, Massimo Paoli, Sandra Fani, Gianluca Festa, Piergiuseppe Calà
Asbestos-related diseases are characterized by a long latency time since exposure. This accounts for a health surveillance programme addressed to asbestos workers to be performed for decades after the cessation of occupational exposure. We describe the health surveillance programme for former asbestos-exposed workers in Tuscany Region (Central Italy), with particular attention to organization and related critical issues. The Deliberation of the Regional Administration of Tuscany (No. 396/2016) supports the programme, defined by a regional group of experts, and defines the public health services where the programme has to be implemented...
March 2018: Epidemiologia e Prevenzione
https://www.readbyqxmd.com/read/29774711/-health-impact-of-asbestos-fibres-naturally-occurring-in-mount-pollino-area-basilicata-region-southern-italy
#6
Angelo Caputo, Marco De Santis, Valerio Manno, Gabriella Cauzillo, Biagio Maria Bruni, Lorenzo Palumbo, Susanna Conti, Pietro Comba
OBJECTIVES: to estimate the health impact of asbestos fibres naturally occurring in Mount Pollino area (Basilicata Region, Southern Italy). DESIGN: geographic mortality, hospitalization, and incidence study. Setting and participant s: population resident in 12 Municipalities of Mount Pollino area with naturally occurring asbestos fibres. MAIN OUTCOME MEASURES: standardized mortality ratio (SMR) and standardized hospitalization rate (SHR) for asbestos-related diseases; standardized incidence ratio (SIR) for mesotheliomas...
March 2018: Epidemiologia e Prevenzione
https://www.readbyqxmd.com/read/29774705/-parliamentary-committee-of-inquiry-about-health-of-italian-soldiers-exposed-to-uranium-asbestos-and-vaccines
#7
Benedetto Terracini
No abstract text is available yet for this article.
March 2018: Epidemiologia e Prevenzione
https://www.readbyqxmd.com/read/29774637/potassium-octatitanate-fibers-induce-persistent-lung-and-pleural-injury-and-are-possibly-carcinogenic-in-male-fischer-344-rats
#8
Mohamed Abdelgied, Ahmed M El-Gazzar, David B Alexander, William T Alexander, Takamasa Numano, Masaaki Iigou, Aya Naiki-Ito, Hirotsugu Takase, Khaled Abbas Abdou, Akihiko Hirose, Yuhji Taquahashi, Jun Kanno, Hiroyuki Tsuda, Satoru Takahashi
Potassium octatitanate fibers (K2 O•8TiO2 , POT fibers) are widely used as an alternative to asbestos. We investigated the pulmonary and pleural toxicity of POT fibers with reference to 2 non-fibrous titanium dioxide nanoparticles (nTiO2 ), photo-reactive anatase (a-nTiO2 ) and inert rutile (r-nTiO2 ). Ten-week old male F344 rats were administered 0.5 ml of 250-μg/ml suspensions of POT fibers, a-nTiO2 , or r-nTiO2 , eight times (1 mg/rat) over a 15 day period by trans-tracheal intrapulmonary spraying (TIPS)...
May 17, 2018: Cancer Science
https://www.readbyqxmd.com/read/29772681/global-asbestos-disaster
#9
Sugio Furuya, Odgerel Chimed-Ochir, Ken Takahashi, Annette David, Jukka Takala
Introduction : Asbestos has been used for thousands of years but only at a large industrial scale for about 100⁻150 years. The first identified disease was asbestosis, a type of incurable pneumoconiosis caused by asbestos dust and fibres. The latest estimate of global number of asbestosis deaths from the Global Burden of Disease estimate 2016 is 3495. Asbestos-caused cancer was identified in the late 1930's but despite today's overwhelming evidence of the strong carcinogenicity of all asbestos types, including chrysotile, it is still widely used globally...
May 16, 2018: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/29757715/accuracy-of-a-mobile-app-to-identify-suspect-asbestos-containing-material-in-australian-residential-settings
#10
Matthew H Govorko, Lin Fritschi, Alison Reid
In situ asbestos in the built environment is a remaining source of exposure in countries that have prohibited the manufacture and use of asbestos. However, it is difficult to identify in situ asbestos-containing material in residential settings. The objective of this study was to evaluate the accuracy of the mobile phone application ("app"), ACM Check, in identifying in situ asbestos located inside and outside of homes compared with onsite inspections conducted by an experienced environmental consultant...
May 14, 2018: Journal of Occupational and Environmental Hygiene
https://www.readbyqxmd.com/read/29757598/switching-brake-materials-to-extremely-wear-resistant-self-lubrication-materials-via-tuning-interface-nanostructures
#11
Qinglun Che, Ga Zhang, Ligang Zhang, Huimin Qi, Guitao Li, Chao Zhang, Feng Guo
Tribological performance of motion components is one of the key aspects that must be considered in a wide range of applications such as vehicles, aircrafts and manufacturing equipment. This work demonstrates that further addition of only low-loading hard nanoparticles into a formulated non-asbestos organic brake material directly switches its functionality to a self-lubrication material. More importantly, the newly developed nanocomposites exhibit an extremely low wear rate. Comprehensive investigations on the friction interface reveal that the great friction and wear-reduction is due to formation of a nanostructured lubricious tribofilm...
May 14, 2018: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/29754410/hi-tech-restoration-by-two-steps-biocleaning-process-of-triumph-of-death-fresco-at-the-camposanto-monumental-cemetery-pisa-italy
#12
Giancarlo Ranalli, Elisabetta Zanardini, Alessia Andreotti, Maria Perla Colombini, Cristina Corti, Pilar Bosch-Roig, Paola De Nuntiis, Giuseppe Lustrato, Paolo Mandrioli, Laura Rampazzi, Carlo Giantomassi, Donatella Zari
AIMS: In this work, the "hi-tech" complex biocleaning and restoration of the 14th-century fresco Triumph of Death (5.6x15.0 m) at the Camposanto Monumental Cemetery (Pisa, Italy) is reported. Since 2000, the restoration based on the biological cleaning of noble medieval frescoes, has been successfully utilized in this site. METHODS AND RESULTS: The novelty of this study is the 2-steps biocleaning process using Pseudomonas stutzeri A29 viable cells, previously applied for recovering other valuable frescoes...
May 13, 2018: Journal of Applied Microbiology
https://www.readbyqxmd.com/read/29754060/origin-and-fate-of-nanoparticles-in-marine-water-preliminary-results
#13
Bożena Graca, Aleksandra Zgrundo, Danuta Zakrzewska, Monika Rzodkiewicz, Jakub Karczewski
The number, morphology and elemental composition of nanoparticles (<100 nm) in marine water was investigated using Variable Pressure Scanning Electron Microscopy (VP-SEM) and Energy-dispersive X-ray spectroscopy (EDS). Preliminary research conducted in the Baltic Sea showed that the number of nanoparticles in seawater varied from undetectable to 380 (x102 ) cm-3 . Wind mixing and density barriers (thermocline) had a significant impact on the abundance and distribution of nanoparticles in water. Many more nanoparticles (mainly nanofibers) were detected in periods of intensive primary production and thermal stratification of water than at the end of the growing season and during periods of strong wind mixing...
May 5, 2018: Chemosphere
https://www.readbyqxmd.com/read/29751048/predicting-emp-hazard-lessons-from-studies-with-inhaled-fibrous-and-non-fibrous-nano-and-micro-particles
#14
Günter Oberdörster, Uschi Graham
Inhalation exposure to elongated cleavage fragments occurring at mineral and rock mining and crushing operations raises important questions regarding potential health effects given their resemblance to fibers with known adverse health effects like amphibole asbestos. Thus, a major goal for establishing a toxicity profile for elongate mineral particles (EMPs) is to identify and characterize a suspected hazard and characterize a risk by examining together results of hazard and exposure assessment. This will require not only knowledge about biokinetics of inhaled EMPs but also about underlying mechanisms of effects induced by retained EMPs...
May 8, 2018: Toxicology and Applied Pharmacology
https://www.readbyqxmd.com/read/29748788/biological-response-of-an-in-vitro-human-3d-lung-cell-model-exposed-to-brake-wear-debris-varies-based-on-brake-pad-formulation
#15
Hana Barosova, Savvina Chortarea, Pavlina Peikertova, Martin J D Clift, Alke Petri-Fink, Jana Kukutschova, Barbara Rothen-Rutishauser
Wear particles from automotive friction brake pads of various sizes, morphology, and chemical composition are significant contributors towards particulate matter. Knowledge concerning the potential adverse effects following inhalation exposure to brake wear debris is limited. Our aim was, therefore, to generate brake wear particles released from commercial low-metallic and non-asbestos organic automotive brake pads used in mid-size passenger cars by a full-scale brake dynamometer with an environmental chamber simulating urban driving and to deduce their potential hazard in vitro...
May 10, 2018: Archives of Toxicology
https://www.readbyqxmd.com/read/29742950/inflammation-in-the-pleural-cavity-following-injection-of-multi-walled-carbon-nanotubes-is-dependent-on-their-characteristics-and-the-presence-of-il-1-genes
#16
Yke Jildouw Arnoldussen, Vidar Skaug, Mona Aleksandersen, Erik Ropstad, Kristine Haugen Anmarkrud, Elin Einarsdottir, Fang Chin-Lin, Cesilie Granum Bjørklund, Mayes Kasem, Einar Eilertsen, Ron N Apte, Shanbeh Zienolddiny
Upon inhalation, multi-walled carbon nanotubes (MWCNTs) may reach the subpleura and pleural spaces, and induce pleural inflammation and/or mesothelioma in humans. However, the mechanisms of MWCNT-induced pathology after direct intrapleural injections are still only partly elucidated. In particular, a role of the proinflammatory interleukin-1 (IL-1) cytokines in pleural inflammation has so far not been published. We examined the MWCNT-induced pleural inflammation, gene expression abnormalities, and the modifying role of IL-1α and β cytokines following intrapleural injection of two types of MWCNTs (CNT-1 and CNT-2) compared with crocidolite asbestos in IL-1 wild-type (WT) and IL-1α/β KO (IL1-KO) mice...
May 9, 2018: Nanotoxicology
https://www.readbyqxmd.com/read/29738812/dosimetry-of-inhaled-elongate-mineral-particles-in-the-respiratory-tract-the-impact-of-shape-factor
#17
Bahman Asgharian, T Price Owen, Eileen D Kuempel, Annie M Jarabek
Inhalation exposure to some types of fibers (e.g., asbestos) is well known to be associated with respiratory diseases and conditions such as pleural plaques, fibrosis, asbestosis, lung cancer, and mesothelioma. In recent years, attention has expanded to other types of elongate mineral particles (EMPs) that may share similar geometry with asbestos fibers but which may differ in mineralogy. Inhalability, dimensions and orientation, and density are major determinants of the aerodynamic behavior for fibers and other EMPs; and the resultant internal dose is recognized as being the critical link between exposure and pathogenesis...
May 5, 2018: Toxicology and Applied Pharmacology
https://www.readbyqxmd.com/read/29737238/asbestos-knowledge-and-awareness-level-in-central-part-of-anatolia
#18
Selma Metintas, Guntulu Ak, Filiz Bogar, Senay Yilmaz, Muzaffer Metintas
Background Asbestos-contaminated soil has been used by people for many years in the rural part of Anatolia. However, there is no program to control usage of asbestos in this region. Objective To determine the knowledge and awareness level about asbestos in a region where asbestos-related diseases are endemic due to environmental exposure to asbestos in the rural setting. Methods This study included 760 participants, recruited using non-probability sampling, who were classified into four groups according to residence and asbestos exposure type (urban, rural; asbestos-exposed, asbestos-unexposed)...
May 8, 2018: International Journal of Occupational and Environmental Health
https://www.readbyqxmd.com/read/29735747/occupational-exposures-and-cancer-a-review-of-agents-and-relative-risk-estimates
#19
Claire Marant Micallef, Kevin David Shield, Isabelle Baldi, Barbara Charbotel, Béatrice Fervers, Anabelle Gilg Soit Ilg, Pascal Guénel, Ann Olsson, Lesley Rushton, Sally J Hutchings, Kurt Straif, Isabelle Soerjomataram
OBJECTIVES: The contribution of occupational exposures to the cancer burden can be estimated using population-attributable fractions, which is of great importance for policy making. This paper reviews occupational carcinogens, and presents the most relevant risk relations to cancer in high-income countries using France as an example, to provide a framework for national estimation of cancer burden attributable to occupational exposure. METHODS: Occupational exposures that should be included in cancer burden studies were evaluated using multiple criteria: classified as carcinogenic or probably carcinogenic by the International Agency for Research on Cancer (IARC) Monographs volumes 1-114, being a primary occupational exposure, historical and current presence of the exposure in France and the availability of exposure and risk relation data...
May 7, 2018: Occupational and Environmental Medicine
https://www.readbyqxmd.com/read/29733442/review-on-the-adverse-health-effects-of-asbestiform-antigorite-a-non-regulated-asbestiform-serpentine-mineral
#20
Xaver Baur
BACKGROUND: Although antigorite is generally described as platy, its fibrous (asbestiform) variant is present widespread in serpentinite rocks. In addition to its primarily fibrous occurrence, asbestiform antigorite may also be formed from serpentinite with massive appearance during tunneling and mining. It is not of commercial interest, but exposure may occur in the certain environments. METHODS AND RESULTS: Detailed studies of the structural features of this antigorite type revealed characteristics closely related to those of chrysotile...
May 7, 2018: American Journal of Industrial Medicine
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