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https://www.readbyqxmd.com/read/29348448/archival-sources-on-asbestos-and-silicosis-in-southern-africa-and-australia
#1
EDITORIAL
Jock McCulloch
No abstract text is available yet for this article.
February 2018: Journal of Public Health Policy
https://www.readbyqxmd.com/read/29346411/evaluation-of-hirst-type-spore-traps-in-outdoor-aspergillaceae-monitoring-during-large-demolition-work-in-hospital
#2
Sophie Tiphaine Loeffert, Philippe Vanhems, Estelle Tissot, Cédric Dananché, Pierre Cassier, Thomas Bénet, Michel Perraud, Michel Thibaudon, Marie-Paule Gustin
Demolition can generate fungal spore suspensions in association with various adverse health effects, such as high risk of invasive aspergillosis in immunocompromised patients. One block of Edouard Herriot Hospital was entirely demolished. The aim of the present study was to evaluate Hirst-type spore traps utility in monitoring outdoor Aspergillaceae (Aspergillus spp. + Penicillium spp.) spores in part of Edouard Herriot Hospital (Lyon, France) undergoing major demolition. Three periods were scheduled in 2015: (A) Gutting of building and asbestos removal, (B) Demolition of floors, (C) Excavation and earthwork...
2018: PloS One
https://www.readbyqxmd.com/read/29342920/asbestos-consumption-in-mongolia-1996-2014
#3
Naransukh Damiran, Arthur Frank
Asbestos is still used in Mongolia in the energy and construction sectors, among others. However, limited data is available on asbestos consumption and asbestos-related disease in Mongolia. The purpose of this paper is to present the available information on the importation of asbestos into Mongolia. We used data on annual asbestos imports between 1996 and 2014 from Mongolian Customs Statistics and the National Council on Toxic and Hazardous Substances Affairs. The uses of this material are also presented with respect to chrysotile alone...
January 15, 2018: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/29342862/heterogeneous-contributing-factors-in-mpm-disease-development-and-progression-biological-advances-and-clinical-implications
#4
REVIEW
Bhairavi Tolani, Luis A Acevedo, Ngoc T Hoang, Biao He
Malignant pleural mesothelioma (MPM) tumors are remarkably aggressive and most patients only survive for 5-12 months; irrespective of stage; after primary symptoms appear. Compounding matters is that MPM remains unresponsive to conventional standards of care; including radiation and chemotherapy. Currently; instead of relying on molecular signatures and histological typing; MPM treatment options are guided by clinical stage and patient characteristics because the mechanism of carcinogenesis has not been fully elucidated; although about 80% of cases can be linked to asbestos exposure...
January 13, 2018: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/29338319/clinical-evaluation-of-circulating-mir-548a-3p-and-20a-expression-in-malignant-pleural-mesothelioma-patients
#5
Marwa Matboli, Ayman E Shafei, Ahmed Em Azazy, Maged Reda, Nashwa El-Khazragy, Ahmed Aly Nagy, Mahmoud A Ali, Mohamed Sobhi, Omar Abdel-Rahman
AIM: miRNAs may act as promising diagnostic and prognostic biomarkers of mesothelioma. This study integrates serum  miR-548a-3p and miR-20a expression based on in silico data analysis followed by clinical validation in malignant mesothelioma patients (malignant pleural mesothelioma [MPM]). PATIENTS & METHODS: Serum miR-548a-3p and  miR-20a level was assessed in the serum of patients with MPM, chronic asbestos exposure and healthy volunteers by quantitative real-time PCR...
January 17, 2018: Biomarkers in Medicine
https://www.readbyqxmd.com/read/29337930/asbestos-related-disorders-in-germany-background-politics-incidence-diagnostics-and-compensation
#6
REVIEW
Xaver Baur
There was some limited use of asbestos at end of the 19th century in industrialized countries including Germany, but its consumption dramatically increased after World War II. The increase in use and exposure was followed by the discovery of high numbers of asbestos-related diseases with a mean latency period of about 38 years in Germany. The strong socio-political pressure from the asbestos industry, its affiliated scientists and physicians has successfully hindered regulatory measures and an asbestos ban for many years; a restrictive stance that is still being unravelled in compensation litigation...
January 16, 2018: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/29336178/evaluation-of-take-home-exposure-to-asbestos-from-handling-asbestos-contaminated-worker-clothing-following-the-abrasive-sawing-of-cement-pipe
#7
Anders Abelmann, Joshua R Maskrey, Jason T Lotter, Aaron M Chapman, Melanie D Nembhard, Jennifer S Pierce, John M Wilmoth, Richard J Lee, Dennis J Paustenbach
Although industrial uses of asbestos have declined since the 1970s, in recent years there has been a renewed interest in para-occupational ("take-home") exposure to these fibers. The aim of this study was to quantify the release of asbestos fibers, if any, during the shaking out of crocidolite- and chrysotile-contaminated clothing in a simulated at-home setting. An exposure study was conducted in which personal and area air samples were collected during the handling (i.e. shake-out) of work clothing (shirt and pants) previously worn by an operator who had cut asbestos-containing cement pipe...
January 16, 2018: Inhalation Toxicology
https://www.readbyqxmd.com/read/29335462/iron-related-toxicity-of-single-walled-carbon-nanotubes-and-crocidolite-fibres-in-human-mesothelial-cells-investigated-by-synchrotron-xrf-microscopy
#8
Francesca Cammisuli, Silvia Giordani, Alessandra Gianoncelli, Clara Rizzardi, Lucia Radillo, Marina Zweyer, Tatiana Da Ros, Murielle Salomé, Mauro Melato, Lorella Pascolo
Carbon nanotubes (CNTs) are promising products in industry and medicine, but there are several human health concerns since their fibrous structure resembles asbestos. The presence of transition metals, mainly iron, in the fibres seems also implicated in the pathogenetic mechanisms. To unravel the role of iron at mesothelial level, we compared the chemical changes induced in MeT-5A cells by the exposure to asbestos (crocidolite) or CNTs at different content of iron impurities (raw-SWCNTs, purified- and highly purified-SWCNTs)...
January 15, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29334525/temporal-patterns-of-exposure-to-asbestos-and-risk-of-asbestosis-an-analysis-of-a-cohort-of-asbestos-textile-workers
#9
Andrea Farioli, Francesco S Violante, Carlo La Vecchia, Eva Negri, Claudio Pelucchi, Giovanna Spatari, Paolo Boffetta, Enrico Pira
OBJECTIVE: The aim of the study was to assess the risk of asbestosis death based on the temporal pattern of exposure to asbestos. METHODS: We followed up a cohort of asbestos textile workers, employed in 1946 to 1984, until November 2013. We measured the duration of the employment, the time since last employment (TSLE), the age, and the year of first employment. Hazard ratios (HR) were estimated through multivariable Cox regression models. RESULTS: We observed 51 asbestosis deaths among 1823 workers...
January 12, 2018: Journal of Occupational and Environmental Medicine
https://www.readbyqxmd.com/read/29326867/cavitary-lung-lesion-suspicious-for-malignancy-reveals-mycobacterium-xenopi
#10
Sumit Fogla, Vaishali M Pansare, Luis G Camero, Uzma Syeda, Naveen Patil, Arun Chaudhury
We report the case of a 68-year-old gentleman who presented with musculoskeletal chest pain which appeared suddenly when he bent over with his dog. The chest pain was localized to the left lower chest and increased with movement and deep breathing. The patient did not complain weight loss, night sweat, fever or chill. He complained of mild cough, with expectoration of whitish mucus. Imaging revealed cavitary chest lesion in the right upper lobe, which was initially suspected to be lung cancer. The patient had a 50-year-old history of smoking 2 packs per day...
2018: Respiratory Medicine Case Reports
https://www.readbyqxmd.com/read/29320402/the-secretory-response-of-rat-peritoneal-mast-cells-on-exposure-to-mineral-fibers
#11
Violetta Borelli, Elisa Trevisan, Vita Francesca, Giuliano Zabucchi
BACKGROUND: Exposure to mineral fibers is of substantial relevance to human health. A key event in exposure is the interaction with inflammatory cells and the subsequent generation of pro-inflammatory factors. Mast cells (MCs) have been shown to interact with titanium oxide (TiO₂) and asbestos fibers. In this study, we compared the response of rat peritoneal MCs challenged with the asbestos crocidolite and nanowires of TiO₂ to that induced by wollastonite employed as a control fiber...
January 10, 2018: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/29316066/smarcb1-ini1-baf47-deficient-pleural-malignant-mesothelioma-with-rhabdoid-features
#12
Noriko Kimura, Masaru Hasegawa, Kenzo Hiroshima
Malignant mesothelioma (MM) with rhabdoid features is an MM variant. Fifteen cases have been reported previously, all of which were combined with other types of MM. Herein, we report an autopsy case of pleural MM with monomorphic rhabdoid features. The patient was a 62-year-old male without a history of asbestos exposure. An autopsy revealed a soft, granular tumor that replaced the entire left pleura and had invaded to the diaphragm and lower lobe of the lung. The tumor cells, which had eosinophilic plump cytoplasm and eccentric nuclei, were loosely cohesive...
January 5, 2018: Pathology International
https://www.readbyqxmd.com/read/29306869/biological-responses-to-asbestos-inhalation-and-pathogenesis-of-asbestos-related-benign-and-malignant-disease
#13
Eduardo Solbes, Richart W Harper
Asbestos comprises a group of fibrous minerals that are naturally occurring in the environment. Because of its natural properties, asbestos gained popularity for commercial applications in the late 19th century and was used throughout the majority of the 20th century, with predominant use in the construction, automotive, and shipbuilding industries. Asbestos has been linked to a spectrum of pulmonary diseases, such as pleural fibrosis and plaques, asbestosis, benign asbestos pleural effusion, small cell lung carcinoma, non-small cell lung carcinoma, and malignant mesothelioma...
January 6, 2018: Journal of Investigative Medicine: the Official Publication of the American Federation for Clinical Research
https://www.readbyqxmd.com/read/29303291/-malign-pleural-mesothelioma-so-far-an-undefeated-tumor
#14
Vítězslav Kolek
Malign pleural mesothelioma is the most frequent primary tumor of the pleura of high aggressiveness. Its most frequent cause is contact with asbestos and, although working with asbestos is already prohibited in developed countries, its incidence is on the increase so far. Diagnostics primarily considers anamnesis, clinical symptoms and immunohistochemical examination of a tumor sample. The basic therapy used over the past 10 years is chemotherapy with cisplatin - pemetrexed combinations. Numerous studies are going on with a different biologically targeted therapy, immunotherapy and other drugs which may improve patients prognosis...
2018: Vnitr̆ní Lékar̆ství
https://www.readbyqxmd.com/read/29298805/correction-germline-bap1-mutational-landscape-of-asbestos-exposed-malignant-mesothelioma-patients-with-family-history-of-cancer
#15
(no author information available yet)
No abstract text is available yet for this article.
January 1, 2018: Cancer Research
https://www.readbyqxmd.com/read/29298350/sialic-acid-binding-lectin-from-bullfrog-eggs-inhibits-human-malignant-mesothelioma-cell-growth-in-vitro-and-in-vivo
#16
Takeo Tatsuta, Toshiyuki Satoh, Shigeki Sugawara, Akiyoshi Hara, Masahiro Hosono
Malignant mesothelioma is an aggressive cancer that results from exposure to asbestos. The therapeutic options for this type of cancer are limited; therefore, the development of novel therapeutic agents is urgently required. Sialic acid-binding lectin isolated from Rana catesbeiana oocytes (cSBL) is a novel therapeutic candidate for cancer, which exhibits antitumor activity mediated through RNA degradation. In the present study, we evaluated the effect of cSBL in vitro and in vivo. Xenograft-competent H2452 and MSTO human mesothelioma cell lines were treated with cSBL, and the pathway by which cSBL induces apoptosis was analyzed...
2018: PloS One
https://www.readbyqxmd.com/read/29286879/capture-efficiency-of-portable-high-efficiency-air-filtration-devices-used-during-building-construction-activities
#17
Derek A Newcomer, Peter LaPuma, Robert Brandys, Amanda Northcross
The portable high efficiency air filtration (PHEAF) device is used to control particulate matter (PM) generated from construction-type activities occurring within the built environment. Examples of activities where PHEAF devices are mobilized include building renovation, asbestos abatement, remediation of microbial contamination and lead-based paint projects. Designed for use on short-term, temporary projects the PHEAF device captures airborne PM using a high efficiency particulate air (HEPA) filter. This study sought to evaluate the capture efficiency of the PHEAF device in a field setting...
December 29, 2017: Journal of Occupational and Environmental Hygiene
https://www.readbyqxmd.com/read/29284684/chest-physician-reported-work-related-long-latency-respiratory-disease-in-great%C3%A2-britain
#18
Melanie Carder, Andrew Darnton, Matthew Gittins, S Jill Stocks, David Ross, Chris M Barber, Raymond M Agius
Much of the current burden of long-latency respiratory disease (LLRD) in Great Britain is attributed to historical asbestos exposure. However, continuing exposure to other agents, notably silica, also contributes to disease burden. The aim of this study was to investigate the incidence of work-related LLRD reported by chest physicians in Great Britain, including variations by age, gender, occupation and suspected agent.LLRD incidence and incidence rate ratios by occupation were estimated (1996-2014). Mesothelioma cases by occupation were compared with proportional mortality ratios...
December 2017: European Respiratory Journal: Official Journal of the European Society for Clinical Respiratory Physiology
https://www.readbyqxmd.com/read/29281122/occupational-exposure-to-textile-dust-and-lung-cancer-risk-results-from-the-icare-study
#19
Soumaya Ben Khedher, Monica Neri, Florence Guida, Mireille Matrat, Sylvie Cenée, Marie Sanchez, Loredana Radoi, Gwenn Menvielle, Emilie Marrer, Danièle Luce, Isabelle Stücker
BACKGROUND: To investigate the association of lung cancer with occupational exposure to textile dust and specifically to cotton dust in the population-based case-control study ICARE. METHODS: Lifelong occupational history of 2926 cases and 3555 controls was collected using standardized questionnaires, with specific questions for textile dust exposure. Odds ratios (ORs) and 95% confidence intervals (CI) were estimated using unconditional logistic regression models controlling for confounding factors including smoking and asbestos exposure...
December 27, 2017: American Journal of Industrial Medicine
https://www.readbyqxmd.com/read/29279043/characterization-of-pulmonary-responses-in-mice-to-asbestos-asbestiform-fibers-using-gene-expression-profiles
#20
Naveena Yanamala, Elena R Kisin, Dmitriy W Gutkin, Michael R Shurin, Martin Harper, Anna A Shvedova
Humans exposed to asbestos and/or asbestiform fibers are at high risk of developing many lung diseases including asbestosis, lung cancer, and malignant mesothelioma. However, the disease-causing potential and specific metabolic mechanisms and pathways associated with various asbestos/asbestiform fiber exposures triggering different carcinogenic and non-carcinogenic outcomes are still largely unknown. The aim of this this study was to investigate gene expression profiles and inflammatory responses to different asbestos/asbestiform fibers at the acute/sub-acute phase that may be related to delayed pathological outcomes observed at later time points...
December 26, 2017: Journal of Toxicology and Environmental Health. Part A
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