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Veterinary chronic pain

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https://www.readbyqxmd.com/read/29747677/use-of-clinical-and-computed-tomography-findings-to-assess-long-term-unsatisfactory-outcome-after-femoral-head-and-neck-ostectomy-in-four-large-breed-dogs
#1
Ciprian Ober, Cosmin Pestean, Lucia Bel, Marian Taulescu, Joshua Milgram, Adrian Todor, Rodica Ungur, Mirela Leșu, Liviu Oana
Femoral head and neck ostectomy (FHNO) is a salvage surgical procedure intended to eliminate hip joint laxity associated pain in the immature dog, or pain due to secondary osteoarthritis in the mature dog. The outcome of the procedure is associated with the size of the dog but the cause of a generally poorer outcome in larger breeds has not been determined. The objective of this study was to assess the long-term results of FHNO associated with unsatisfactory functional outcome by means of clinical examination and computed tomography (CT) scanning...
May 10, 2018: Acta Veterinaria Scandinavica
https://www.readbyqxmd.com/read/29727900/diagnosis-and-treatment-of-infraspinatus-tendon-bursa-ossification-in-a-eurasian-dog
#2
Julia Ungru, Stephan Hungerbühler, Wolfgang Henninger, Petra Klupiec, Julia Bödeker, Anna Langer, Michael Fehr, Oliver Harms
A 4-year-old male Eurasian Dog presented at our veterinary clinic with a history of perpetual forelimb lameness in both thoracic limbs. In the clinical exploration, direct pressure over the infraspinatus tendon of insertion caused pain in both thoracic forelimbs and a firm band-like structure was palpable. No improvement was observed after treatment with rest, non-steroidal anti-inflammatory drugs and an intralesional injection of a long-acting glucocorticoid. Radiographic examination, ultrasonographic exploration and computed tomography were performed, identifying ossified structures lateral to the proximal humerus and an irregular roughened periosteum at the insertion and tendon of the infraspinatus muscle on both sides...
April 2018: Tierärztliche Praxis. Ausgabe K, Kleintiere/Heimtiere
https://www.readbyqxmd.com/read/29706091/behavioral-awareness-in-the-feline-consultation-understanding-physical-and-emotional-health
#3
Debra F Horwitz, Ilona Rodan
Practical relevance: Awareness of the strong connection between observed behavior and physical and emotional health is essential for patient welfare. It is often a change in the individual's normal behavior that informs owners and veterinarians of the possibility of illness, pain and stress/distress. There is ample evidence in the feline literature that medical and behavioral health go hand in hand. In most feline cases, medical and behavioral conditions contribute concurrently to clinical signs. Clinical challenges: Our domestic cats do not express change in physiological and emotional states in a way that is easily recognized...
May 2018: Journal of Feline Medicine and Surgery
https://www.readbyqxmd.com/read/29649262/antinociceptive-antibiotics-loaded-into-solid-lipid-nanoparticles-of-prolonged-release-measuring-pharmacological-efficiency-and-time-span-on-chronic-monoarthritis-rats
#4
Carlos Valdes, Gonzalo Bustos, Jose L Martinez, Claudio Laurido
Pain is a sensory experience of a complex physiological nature in which is not only involved the nervous system. Among its many features is the development of chronic pain that is more complicated to treat because of the central somatization processes involved, becoming inefficient treatments used in other forms of pain. Among them is the role of glial cells, whose participation is such that some authors have proposed to chronic pain as a gliopathy. Because of this, the drug target of possible treatments focuses on modulating nociceptive response affecting transduction into the central nervous system through affecting synapses in the dorsal horn of the spinal cord...
2018: PloS One
https://www.readbyqxmd.com/read/29584640/greenshell%C3%A2-mussels-a-review-of-veterinary-trials-and-future-research-directions
#5
REVIEW
Charles T Eason, Serean L Adams, Jonathan Puddick, Donato Romanazzi, Matthew R Miller, Nick King, Sarah Johns, Elizabeth Forbes-Blom, Paul A Hessian, Lisa K Stamp, Michael A Packer
The therapeutic benefits of Greenshell™ mussel (GSM; Perna canaliculus ) preparations have been studied using in vitro test systems, animal models, and human clinical trials focusing mainly on anti-inflammatory and anti-arthritic effects. Activity is thought to be linked to key active ingredients that include omega-3 polyunsaturated fatty acids, a variety of carotenoids and other bioactive compounds. In this paper, we review the studies that have been undertaken in dogs, cats, and horses, and outline new research directions in shellfish breeding and high-value nutrition research programmes targeted at enhancing the efficacy of mussel and algal extracts...
March 27, 2018: Veterinary Sciences
https://www.readbyqxmd.com/read/29565949/evaluation-of-the-effect-of-duration-on-the-efficacy-of-pulsed-radiofrequency-in-an-animal-model-of-neuropathic-pain
#6
Eiad A Ramzy, Khaled I Khalil, Eman M Nour, Mohammed F Hamed, Mohamed A Taha
BACKGROUND: Pulsed radiofrequency (PRF) is increasingly used in clinical practice, especially in neuropathic pain disorders. Although PRF is not new to clinical use, there are significant gaps in knowledge regarding its effectiveness. OBJECTIVES: The current study was conducted to evaluate the effect of duration of application of PRF on its analgesic efficacy in improvement of neuropathic pain. STUDY DESIGN: A randomized experimental trial...
March 2018: Pain Physician
https://www.readbyqxmd.com/read/29553907/indications-for-and-outcomes-of-limb-amputation-in-goats-and-sheep
#7
Lisa Gamsjaeger, Munashe Chigerwe
OBJECTIVE To characterize indications for and clinical outcomes of limb amputation in goats and sheep. DESIGN Retrospective case series and observational study. ANIMALS Goats (n = 15) and sheep (7) that underwent partial or complete limb amputation at the University of California-Davis Veterinary Medical Teaching Hospital from January 1, 1985, through December 31, 2015. PROCEDURES Medical records of qualifying goats and sheep were reviewed and data extracted regarding signalment, use of animal, characteristics of the amputated limb, duration of hospitalization, outcome, and surgery-associated complications...
April 1, 2018: Journal of the American Veterinary Medical Association
https://www.readbyqxmd.com/read/29197113/pyelonephritis-in-dogs-retrospective-study-of-47-histologically-diagnosed-cases-2005-2015
#8
J Bouillon, E Snead, J Caswell, C Feng, P Hélie, J Lemetayer
BACKGROUND: The clinicopathologic aspects of pyelonephritis have not been reported in companion animals. HYPOTHESIS/OBJECTIVES: To evaluate the prevalence of pyelonephritis diagnosed in dogs in a academic referral population, describe the clinical signs and the diagnostic test results in dogs with pyelonephritis, and identify concurrent disorders in order to determine potential risk factors for pyelonephritis. ANIMALS: Forty-seven dogs with a histopathologic diagnosis of pyelonephritis from the teaching hospitals of three Canadian veterinary colleges...
January 2018: Journal of Veterinary Internal Medicine
https://www.readbyqxmd.com/read/29107824/antimicrobial-photodynamic-therapy-apdt-and-photobiomodulation-pbm-660nm-in-a-dog-with-chronic-gingivostomatitis
#9
Paula Abreu Villela, Naiá de Carvalho de Souza, Juliana Durigan Baia, Marco Antonio Gioso, Ana Cecília Corrêa Aranha, Patrícia Moreira de Freitas
Chronic gingivostomatitis in dogs is an inflammatory syndrome of the oral cavity, which treatment and control of concomitant periodontitis allow healing in most of the cases. In the presence of recurrent lesions, invasive methods are necessary to treat lesions and pain. As a conservative adjuvant method, photobiomodulation (PBM) with low power laser is able to promote reduction of tissue pain and tissue inflammation besides increasing vascularization and healing, restoring the normal function of the irradiated organ in a shorter time...
December 2017: Photodiagnosis and Photodynamic Therapy
https://www.readbyqxmd.com/read/28955475/single-pedicle-hinge-flap-performed-by-shelter-medicine-team-resolves-chronic-antebrachial-wound-in-a-cat
#10
Jodi M Richardson, Jacob M Shivley, Philip A Bushby
CASE SUMMARY: An approximately 3-year-old, male domestic longhair cat was presented to a mobile veterinary unit for routine neuter. Preoperative physical examination revealed an approximately 5 cm × 2 cm scab on the craniolateral portion of the left antebrachium. The cat was anesthetized for the neuter using an injectable anesthesia protocol. After castration, the wound area on the antebrachium was clipped, copiously lavaged and the wound edges were surgically debrided. Injectable antibiotics and analgesic management were instituted...
July 2017: JFMS Open Reports
https://www.readbyqxmd.com/read/28822691/fatal-meningitis-in-swine-after-intrathecal-administration-of-adeno-associated-virus-expressing-syngeneic-interleukin-10
#11
Mark D Unger, Josef Pleticha, James E Collins, Anibal G Armien, Jennifer L Brazzell, Laura K Newman, Lukas F Heilmann, Jodi A Scholz, Timothy P Maus, Andreas S Beutler
Interleukin-10 (IL-10) delivered by intrathecal (i.t.) gene vectors is a candidate investigational new drug (IND) for several chronic neurological disorders such as neuropathic pain. We performed a preclinical safety study of IL-10. A syngeneic large animal model was used delivering porcine IL-10 (pIL-10) to the i.t. space in swine by adeno-associated virus serotype 8 (AAV8), a gene vector that was previously found to be nontoxic in the i.t. space. Unexpectedly, animals became ill, developing ataxia, seizures, and an inability to feed and drink, and required euthanasia...
November 1, 2017: Molecular Therapy: the Journal of the American Society of Gene Therapy
https://www.readbyqxmd.com/read/28768536/a-novel-composite-formulation-of-palmitoylethanolamide-and-quercetin-decreases-inflammation-and-relieves-pain-in-inflammatory-and-osteoarthritic-pain-models
#12
Domenico Britti, Rosalia Crupi, Daniela Impellizzeri, Enrico Gugliandolo, Roberta Fusco, Carlo Schievano, Valeria Maria Morittu, Maurizio Evangelista, Rosanna Di Paola, Salvatore Cuzzocrea
BACKGROUND: Osteoarthritis (OA) is a common progressive joint disease in dogs and cats. The goal of OA treatment is to reduce inflammation, minimize pain, and maintain joint function. Currently, non-steroidal anti-inflammatory drugs (e.g., meloxicam) are the cornerstone of treatment for OA pain, but side effects with long-term use pose important challenges to veterinary practitioners when dealing with OA pain. Palmitoylethanolamide (PEA) is a naturally-occurring fatty acid amide, locally produced on demand by tissues in response to stress...
August 2, 2017: BMC Veterinary Research
https://www.readbyqxmd.com/read/27612660/serum-concentration-of-ketamine-and-antinociceptive-effects-of-ketamine-and-ketamine-lidocaine-infusions-in-conscious-dogs
#13
RANDOMIZED CONTROLLED TRIAL
Ubedullah Kaka, Bullo Saifullah, Adamu Abdul Abubakar, Yong Meng Goh, Sharida Fakurazi, Asmatullah Kaka, Atique Ahmed Behan, Mahdi Ebrahimi, Hui Cheng Chen
BACKGROUND: Central sensitization is a potential severe consequence of invasive surgical procedures. It results in postoperative and potentially chronic pain enhancement. It results in postoperative pain enhancement; clinically manifested as hyperalgesia and allodynia. N-methyl-D-aspartate (NMDA) receptor plays a crucial role in the mechanism of central sensitisation. Ketamine is most commonly used NMDA-antagonist in human and veterinary practice. However, the antinociceptive serum concentration of ketamine is not yet properly established in dogs...
September 9, 2016: BMC Veterinary Research
https://www.readbyqxmd.com/read/27551420/understanding-factors-that-facilitate-the-inclusion-of-pain-education-in-undergraduate-curricula-perspectives-from-a-uk-survey
#14
Eloise Cj Carr, Emma V Briggs, Michelle Briggs, Nick Allcock, Pauline Black, Derek Jones
BACKGROUND: Studies in Europe, North America and Australasia suggest that one in five adults suffer from pain. There is increasing recognition that pain, particularly chronic pain, represents a global health burden. Many studies, including two national surveys exploring the content of undergraduate curricula for pain education, identify that documented pain education in curricula was limited and fragmentary. METHODS: The study design used a questionnaire which included an open text comment box for respondents to add 'further comments' as part of larger study previously published...
May 2016: British Journal of Pain
https://www.readbyqxmd.com/read/27534983/dogs-attending-primary-care-practice-in-england-with-clinical-signs-suggestive-of-chiari-like-malformation-syringomyelia
#15
S Sanchis-Mora, L Pelligand, C L Thomas, H A Volk, S M Abeyesinghe, D C Brodbelt, D B Church, P C Thomson, P D McGreevy, D G O'Neill
Chiari-like malformation/syringomyelia (CM/SM) in dogs describes a developmental disorder that can cause pain and reduced quality of life. This retrospective study aimed to report the period prevalence, clinical signs and risk factors for diagnosis of symptomatic CM/SM in the veterinary primary-care setting using a cross-sectional design. The study population included all dogs within the VetCompass Programme (September 1, 2009-June 13, 2014). Overall, the period prevalence of symptomatic CM/SM was 0.05 per cent (95 per cent CI 0...
October 29, 2016: Veterinary Record
https://www.readbyqxmd.com/read/27529257/resiniferatoxin-the-evolution-of-the-molecular-scalpel-for-chronic-pain-relief
#16
REVIEW
Dorothy Cimino Brown
Control of chronic pain is frequently inadequate or can be associated with debilitating side effects. Ablation of certain nociceptive neurons, while retaining all other sensory modalities and motor function, represents a new therapeutic approach to controlling severe pain while avoiding off-target side effects. transient receptor potential cation channel subfamily V member 1 (TRPV1) is a calcium permeable nonselective cation channel expressed on the peripheral and central terminals of small-diameter sensory neurons...
August 11, 2016: Pharmaceuticals
https://www.readbyqxmd.com/read/27478852/texas-occurrence-of-lyme-disease-and-its-neurological-manifestations
#17
Jad A Dandashi, Damir Nizamutdinov, Samantha Dayawansa, Ekokobe Fonkem, Jason H Huang
Today, Lyme disease is the most commonly reported tick-borne disease in the United States and Europe. The culprits behind Lyme disease are the Borrelia species of bacteria. In the USA, Borrelia burgdorferi causes the majority of cases, while in Europe and Asia Borrelia afzelii and Borrelia garinii carry the greatest burden of disease. The clinical manifestations of Lyme disease have been identified as early localized, early disseminated, and late chronic. The neurological effects of Lyme disease include both peripheral and central nervous systems involvement, including focal nerve abnormalities, cranial neuropathies, painful radiculoneuritis, meningitis, and/or toxic metabolic encephalopathy, known as Lyme encephalopathy...
June 2016: Journal of Neuroinfectious Diseases
https://www.readbyqxmd.com/read/27169151/complete-ostectomy-of-middle-phalanx-and-partial-ostectomy-of-proximal-phalanx-in-a-brown-swiss-calf-for-treatment-of-purulent-arthritis-of-the-proximal-interphalangeal-joint-and-adjacent-severe-osteomyelitis
#18
Johann Burgstaller, Johann Kofler
A five month old Brown Swiss heifer calf (212 kg body mass) with severe left hind limb lameness, caused by a wound of the lateral digit was referred to the veterinary teaching hospital. The calf showed a score 4 of 5 lameness on the left hind limb. A scarified skin lesion with a fistula formation and purulent exudate was observed at the level of the proximal interphalangeal joint (PIJ) of the lateral digit of the left hind. The PIJ region and the lateral digit were severely swollen and painful. Ultrasonography showed a moderate anechoic effusion of the lateral digital flexor tendon sheet (DFTS) and a severe heterogeneous hypoechoic effusion with some small hyperechoic areas of the plantar and dorsal pouch of the PIJ...
March 2016: Berliner und Münchener Tierärztliche Wochenschrift
https://www.readbyqxmd.com/read/26942185/managing-neuropathic-pain-in-dogs
#19
REVIEW
Sarah A Moore
Disorders of the somatosensory system such as neuropathic pain are common in people with chronic neurologic and musculoskeletal diseases, yet these conditions remain an underappreciated morbidity in veterinary patients. This is likely because assessment of neuropathic pain in people relies heavily on self-reporting, something our veterinary patients are not able to do. The development of neuropathic pain is a complex phenomenon, and concepts related to it are frequently not addressed in the standard veterinary medical curriculum such that veterinarians may not recognize this as a potential problem in patients...
2016: Frontiers in Veterinary Science
https://www.readbyqxmd.com/read/26817587/tungiasis-associated-morbidity-in-pigs-and-dogs-in-endemic-villages-of-uganda
#20
Francis Mutebi, Jürgen Krücken, Hermann Feldmeier, Charles Waiswa, Norbert Mencke, Georg von Samson-Himmelstjerna
BACKGROUND: Tunga penetrans (Insecta, Siphonaptera, Tungidae) causes severe morbidity among heavily infected humans and animals in Latin America and sub-Saharan Africa. The clinical pathology of tungiasis in animals has never been studied systematically. METHODS: This was a cross-sectional study conducted between January to March 2015, aimed at describing tungiasis-associated clinical pathology in 121 and 20 T. penetrans-infected pigs and dogs, living in nine and five endemic rural villages respectively located in Bugiri District, Busoga, Uganda...
January 27, 2016: Parasites & Vectors
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