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Canine Cruciate ligament

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https://www.readbyqxmd.com/read/28094860/tta-rapid-in-the-treatment-of-the-canine-cruciate-deficient-stifle-short-and-medium-term-outcome
#1
S J Butterworth, D M Kydd
OBJECTIVES: To evaluate complications, short- and medium-term outcomes following treatment of lameness associated with cranial cruciate ligament insufficiency in dogs using the "TTA-Rapid" technique. METHODS: Patient records from two veterinary clinics were retrospectively examined to collect data from cases treated over a period of 21 months. An owner postal questionnaire using a clinical metrology instrument (Liverpool Osteoarthritis in Dogs) evaluated medium-term outcome of at least six months...
January 2017: Journal of Small Animal Practice
https://www.readbyqxmd.com/read/28090443/topographical-and-depth-dependent-glycosaminoglycan-concentration-in-canine-medial-tibial-cartilage-3-weeks-after-anterior-cruciate-ligament-transection-surgery-a-microscopic-imaging-study
#2
Daniel Mittelstaedt, David Kahn, Yang Xia
BACKGROUND: Medical imaging has become an invaluable tool to diagnose damage to cartilage. Depletion of glycosaminoglycans (GAG) has been shown to be one of the early signs of cartilage degradation. In order to investigate the topographical changes in GAG concentration caused by the anterior cruciate ligament transection (ACLT) surgery in a canine model, microscopic magnetic resonance imaging (µMRI) and microscopic computed tomography (µCT) were used to measure the GAG concentration with correlation from a biochemical assay, inductively coupled plasma optical emission spectroscopy (ICP-OES), to understand where the topographical and depth-dependent changes in the GAG concentration occur...
December 2016: Quantitative Imaging in Medicine and Surgery
https://www.readbyqxmd.com/read/28075493/joint-stability-after-canine-cranial-cruciate-ligament-graft-reconstruction-varies-among-femoral-fixation-sites
#3
Louisa K Ho-Eckart, Masahiro Seki, Lindsey M Luizza, Michael T Kearney, Mandi J Lopez
OBJECTIVE: To quantify stability in cranial cruciate ligament (CrCL) deficient canine stifles with hamstring grafts affixed at 3 femoral locations. STUDY DESIGN: Canine stifle motion study using a multi-cohort, repeated measures design. SAMPLE POPULATION: 27 canine cadaver stifles. METHODS: Hamstring grafts (HG) were affixed at the gracilis-semitendinosus insertion and on the lateral femur (1) proximal trochlear ridge (TR), (2) craniodistal to fabella (F), or (3) condyle center (CC)...
February 2017: Veterinary Surgery: VS
https://www.readbyqxmd.com/read/28068982/effect-of-proximal-translation-of-the-osteotomized-tibial-tuberosity-during-tibial-tuberosity-advancement-on-patellar-position-and-patellar-ligament-angle
#4
Jack D Neville-Towle, Mariano Makara, Kenneth A Johnson, Katja Voss
BACKGROUND: Cranial cruciate ligament insufficiency is a common orthopaedic problem in canine patients. This cadaveric and radiographic study was performed with the aim of determining the effect of proximal translation of the tibial tuberosity during tibial tuberosity advancement (TTA) on patellar position (PP) and patellar ligament angle (PLA). RESULTS: Disarticulated left hind limb specimens harvested from medium to large breed canine cadavers (n = 6) were used for this study...
January 9, 2017: BMC Veterinary Research
https://www.readbyqxmd.com/read/28029280/biomechanics-of-an-orthosis-managed-cranial-cruciate-ligament-deficient-canine-stifle-joint-predicted-by-use-of-a-computer-model
#5
Gina E Bertocci, Nathan P Brown, Patrice M Mich
OBJECTIVE To evaluate effects of an orthosis on biomechanics of a cranial cruciate ligament (CrCL)-deficient canine stifle joint by use of a 3-D quasistatic rigid-body pelvic limb computer model simulating the stance phase of gait and to investigate influences of orthosis hinge stiffness (durometer). SAMPLE A previously developed computer simulation model for a healthy 33-kg 5-year-old neutered Golden Retriever. PROCEDURES A custom stifle joint orthosis was implemented in the CrCL-deficient pelvic limb computer simulation model...
January 2017: American Journal of Veterinary Research
https://www.readbyqxmd.com/read/28024306/a-canine-arthroscopic-anterior-cruciate-ligament-reconstruction-model-for-study-of-synthetic-augmentation-of-tendon-allografts
#6
James L Cook, Pat Smith, James P Stannard, Ferris Pfeiffer, Keiichi Kuroki, Chantelle C Bozynski, Cristi Cook
Novel graft types, fixation methods, and means for augmenting anterior cruciate ligament (ACL) reconstructions require preclinical validation prior to safe and effective clinical application. The objective of this study was to describe and validate a translational canine model for all-inside arthroscopic complete ACL reconstruction using a quadriceps tendon allograft with internal brace (QTIB). With institutional approval, adult research hounds underwent complete transection of the native ACL followed by all-inside ACL reconstruction using the novel QTIB construct with suspensory fixation (n = 10)...
December 26, 2016: Journal of Knee Surgery
https://www.readbyqxmd.com/read/27739555/evaluation-of-the-relationship-of-tibiofemoral-kinematics-before-and-after-total-knee-replacement-in-an-in-vitro-model-of-cranial-cruciate-deficiency-in-the-dog
#7
Rebecca N Howie, Timothy L Foutz, Curtis C Cathcart, Jeff S Burmeister, Steve C Budsberg
OBJECTIVE: To investigate the relationship between tibiofemoral kinematics before and after total knee replacement (TKR) in vitro. ANIMALS: Eight canine hemipelves. METHODS: A modified Oxford Knee Rig was used to place cadaveric limbs through a range of passive motion allowing the kinematics of the stifle to be evaluated. Four measurements were performed: a control stage, followed by a cranial cruciate transection stage, then following TKR with the musculature intact stage, and finally TKR with removal of limb musculature stage...
November 23, 2016: Veterinary and Comparative Orthopaedics and Traumatology: V.C.O.T
https://www.readbyqxmd.com/read/27709221/evaluation-of-an-intra-articular-synthetic-ligament-for-treatment-of-cranial-cruciate-ligament-disease-in-dogs-a-six-month-prospective-clinical-trial
#8
Matthew D Barnhart, Karl Maritato, Kemal Schankereli, Harry Wotton, Steven Naber
OBJECTIVE: Evaluate the short-term outcomes of a novel synthetic ligament for treatment of naturally occurring canine cranial cruciate ligament disease. STUDY DESIGN: Prospective clinical study. ANIMALS: Dogs with unilateral cranial cruciate ligament disease (n = 50). METHODS: Patient parameters evaluated included a five-point lameness score, evaluation of craniocaudal stifle instability, and radiographic findings over 24 weeks...
November 23, 2016: Veterinary and Comparative Orthopaedics and Traumatology: V.C.O.T
https://www.readbyqxmd.com/read/27575050/autologous-bone-marrow-derived-mesenchymal-stem-cells-modulate-molecular-markers-of-inflammation-in-dogs-with-cruciate-ligament-rupture
#9
Peter Muir, Eric C Hans, Molly Racette, Nicola Volstad, Susannah J Sample, Caitlin Heaton, Gerianne Holzman, Susan L Schaefer, Debra D Bloom, Jason A Bleedorn, Zhengling Hao, Ermias Amene, M Suresh, Peiman Hematti
Mid-substance rupture of the canine cranial cruciate ligament rupture (CR) and associated stifle osteoarthritis (OA) is an important veterinary health problem. CR causes stifle joint instability and contralateral CR often develops. The dog is an important model for human anterior cruciate ligament (ACL) rupture, where rupture of graft repair or the contralateral ACL is also common. This suggests that both genetic and environmental factors may increase ligament rupture risk. We investigated use of bone marrow-derived mesenchymal stem cells (BM-MSCs) to reduce systemic and stifle joint inflammatory responses in dogs with CR...
2016: PloS One
https://www.readbyqxmd.com/read/27493284/post-operative-complications-associated-with-the-arthrex-canine-cranial-cruciate-ligament-repair-anchor-system-in-small-to-medium-sized-dogs-a-retrospective-analysis-2009-2012
#10
Nick S Rappa, Robert M Radasch
This study classified and determined the post-operative complication rate associated with stabilization of cranial (CCL) ligament deficient stifles in small- to medium-sized dogs with the Arthrex Canine Cranial Cruciate Ligament Repair Anchor System (CCLRAS). Eighty-five medical records from 2009 to 2012 from 1 institution were evaluated. Complications were classified according to previously proposed definitions for orthopedic studies in veterinary medicine. Fifty-two owners were contacted by telephone at least 6 months after surgery and given a questionnaire to classify complications related to the implant...
August 2016: Canadian Veterinary Journal. la Revue Vétérinaire Canadienne
https://www.readbyqxmd.com/read/27439659/evaluation-of-surface-blood-flow-in-intact-and-ruptured-canine-cruciate-ligaments-using-laser-doppler-flowmetry
#11
Joakim Testuz, Judith Howard, Antonio Pozzi, Ulrich Rytz, Christiane Krudewig, David Spreng, Simone Forterre
OBJECTIVE: To evaluate the usefulness of laser Doppler flowmetry (LDF) to measure surface blood flow in canine cruciate ligaments, compare measurements in different sites of intact and partially ruptured canine cranial cruciate ligaments (CrCL) and intact caudal cruciate ligaments (CaCL), and investigate any association between surface blood flow in partially ruptured CrCL and synovitis or duration of clinical signs. STUDY DESIGN: Case-controlled clinical study...
September 20, 2016: Veterinary and Comparative Orthopaedics and Traumatology: V.C.O.T
https://www.readbyqxmd.com/read/27398949/surgical-technique-and-initial-clinical-experience-with-a-novel-extracapsular-articulating-implant-for-treatment-of-the-canine-cruciate-ligament-deficient-stifle-joint
#12
Veronica J Barkowski, Neil A Embleton
OBJECTIVE: To describe the surgical technique, clinical efficacy, and complications using the Simitri Stable in Stride(®) extracapsular articulating implant (EAI) to treat naturally occurring stifle instability due to cranial cruciate ligament (CrCL) insufficiency. STUDY DESIGN: Prospective case series. ANIMALS: Client-owned dogs with CrCL-deficient stifles (n=60 dogs; 66 stifles). METHODS: An EAI was applied to the medial aspect of the distal femur and proximal tibia after stifle exploration and treatment of joint pathology...
August 2016: Veterinary Surgery: VS
https://www.readbyqxmd.com/read/27357273/feasibility-of-stifle-medial-meniscal-release-in-toy-breed-dogs-with-and-without-a-joint-distractor
#13
Kwan Kim, Haebeom Lee, Guillaume R Ragetly
OBJECTIVE: To investigate the feasibility of medial meniscal release (MMR) during stifle arthroscopy in toy breed dogs with and without a joint distractor. STUDY DESIGN: Experimental cadaveric study. SAMPLE POPULATION: Stifles (n = 40) from 20 canine cadavers (1.8-5.1 kg). METHODS: Paired stifles were randomly assigned to the joint distractor group and the control group (n = 20 each). All stifles underwent arthroscopic transection of the cranial cruciate ligament followed by a release of the caudomedial meniscotibial ligament...
July 2016: Veterinary Surgery: VS
https://www.readbyqxmd.com/read/27348887/epidemiologic-study-of-dogs-with-the-displacement-or-deformity-of-the-medial-and-lateral-fabellae-in-japan
#14
Shinji Yasukawa, Kazuya Edamura, Koji Tanegashima, Hirotaka Kai, Go Higuchi, Momoyo Nagasawa, Kenji Teshima, Kazushi Asano, Tomohiro Nakayama
The prevalences of displacement and deformity of the medial and lateral fabellae in dogs were investigated. This was a retrospective epidemiologic study. Radiographs of canine stifle joints (1022 limbs, 534 dogs) were obtained. The images were taken at the Nihon University Animal Medical Center and three private animal hospitals from January 2003 to July 2012. The position and morphology of the medial or lateral fabella were evaluated on the radiographs. The prevalence of displacement of the medial and lateral fabellae was 1...
February 2016: Japanese Journal of Veterinary Research
https://www.readbyqxmd.com/read/27080496/proteomic-differences-between-native-and-tissue-engineered-tendon-and-ligament
#15
Yalda A Kharaz, Simon R Tew, Mandy Peffers, Elizabeth G Canty-Laird, Eithne Comerford
Tendons and ligaments (T/Ls) play key roles in the musculoskeletal system, but they are susceptible to traumatic or age-related rupture, leading to severe morbidity as well as increased susceptibility to degenerative joint diseases such as osteoarthritis. Tissue engineering represents an attractive therapeutic approach to treating T/L injury but it is hampered by our poor understanding of the defining characteristics of the two tissues. The present study aimed to determine differences in the proteomic profile between native T/Ls and tissue engineered (TE) T/L constructs...
May 2016: Proteomics
https://www.readbyqxmd.com/read/26910877/canine-stifle-biomechanics-associated-with-a-novel-extracapsular-articulating-implant-predicted-using-a-computer-model
#16
Gina E Bertocci, Nathan P Brown, Neil A Embleton, Veronica J Barkowski
OBJECTIVE: To evaluate the influence of the Simitri Stable in Stride™ extracapsular articulating implant (EAI) on canine stifle biomechanics in the cranial cruciate ligament (CrCL)-deficient stifle using a 3-dimensional (3D) quasi-static rigid body canine pelvic limb computer model simulating the stance phase of gait. STUDY DESIGN: Computer simulations. ANIMALS: Five-year-old neutered male golden retriever (33 kg). METHODS: The EAI was implemented in a previously developed 3D CrCL-deficient canine pelvic limb computer simulation model...
April 2016: Veterinary Surgery: VS
https://www.readbyqxmd.com/read/26902805/synovial-fluid-matrix-metalloproteinase-2-and-9-activities-in-dogs-suffering-from-joint-disorders
#17
Kohei Murakami, Shingo Maeda, Tomohiro Yonezawa, Naoaki Matsuki
The activity of matrix metalloproteinase (MMP)-2 and MMP-9 in synovial fluids (SF) sampled from dogs with joint disorders was investigated by gelatin zymography and densitometry. Pro-MMP-2 showed similar activity levels in dogs with idiopathic polyarthritis (IPA; n=17) or canine rheumatoid arthritis (cRA; n=4), and healthy controls (n=10). However, dogs with cranial cruciate ligament rupture (CCLR; n=5) presented significantly higher pro-MMP-2 activity than IPA and healthy dogs. Meanwhile, dogs with IPA exhibited significantly higher activity of pro- and active MMP-9 than other groups...
July 1, 2016: Journal of Veterinary Medical Science
https://www.readbyqxmd.com/read/26886872/topographical-variations-in-zonal-properties-of-canine-tibial-articular-cartilage-due-to-early-osteoarthritis-a-study-using-7-t-magnetic-resonance-imaging-at-microscopic-resolution
#18
Ji Hyun Lee, Farid Badar, John Matyas, Xianggui Qu, Yang Xia
OBJECTIVE: Our aim was to determine topographical variations in zonal properties of articular cartilage over the medial tibia in an experimental osteoarthritis (OA) model using 7-T magnetic resonance imaging (MRI). MATERIALS AND METHODS: An anterior cruciate ligament (ACL)-transection canine model was subjected to study at 8 (six) and 12 (seven) weeks after the surgery. Each medial tibia was divided into five topographical locations. For each specimen, T2 relaxation (at 0° and 55°) was quantified at microscopic resolution...
August 2016: Magma
https://www.readbyqxmd.com/read/26853947/suspensory-versus-interference-screw-fixation-for-arthroscopic-anterior-cruciate-ligament-reconstruction-in-a-translational-large-animal-model
#19
Patrick A Smith, James P Stannard, Ferris M Pfeiffer, Keiichi Kuroki, Chantelle C Bozynski, James L Cook
PURPOSE: To compare all-inside cortical-button suspensory fixation in sockets versus interference screw fixation in tunnels with respect to clinical, histologic, and biomechanical assessments of all-soft tissue (AST) tendon autografts used for anterior cruciate ligament (ACL) reconstruction in a canine model. METHODS: By use of a validated "hybrid" double-bundle ACL reconstruction technique (reconstruction of the anteromedial bundle with preservation of the native posterolateral bundle), dogs were randomly assigned to undergo either suspensory fixation in sockets (n = 6) or interference screw fixation in tunnels (n = 6)...
June 2016: Arthroscopy: the Journal of Arthroscopic & related Surgery
https://www.readbyqxmd.com/read/26831152/3d-fse-cube-and-vipr-atr-3-0-tesla-magnetic-resonance-imaging-predicts-canine-cranial-cruciate-ligament-structural-properties
#20
Molly Racette, Habib Al saleh, Kenneth R Waller, Jason A Bleedorn, Ronald P McCabe, Ray Vanderby, Mark D Markel, Sabrina H Brounts, Walter F Block, Peter Muir
Estimation of cranial cruciate ligament (CrCL) structural properties in client-owned dogs with incipient cruciate rupture would be advantageous. The objective of this study was to determine whether magnetic resonance imaging (MRI) measurement of normal CrCL volume in an ex-vivo canine model predicts structural properties. Stifles from eight dogs underwent 3.0 Tesla 3D MRI. CrCL volume and normalized median grayscale values were determined using 3D Fast Spin Echo (FSE) Cube and Vastly under-sampled Isotropic PRojection (VIPR)-alternative repetition time (aTR) sequences...
March 2016: Veterinary Journal
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