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https://www.readbyqxmd.com/read/29332730/biomechanical-factors-associated-with-running-economy-and-performance-of-elite-kenyan-distance-runners-a-systematic-review
#1
REVIEW
Nassib Tawa, Quinette Louw
BACKGROUND: Running economy (RE) is a determinant of performance in endurance sports and is a complex multi-factorial measure which reflects the combined functioning of bio-mechanical, neuro-muscular, metabolic and cardio-respiratory factors some of which are hereditary or adapt to coaching. Kenyan distance runners have dominated major global events with their unmatched performance for decades and this phenomenon has prompted several investigations aimed at establishing possible factors associated with their performance...
January 2018: Journal of Bodywork and Movement Therapies
https://www.readbyqxmd.com/read/29331050/exercise-counteracts-lipotoxicity-by-improving-lipid-turnover-and-lipid-droplet-quality
#2
Evelyn Zacharewicz, Matthijs K C Hesselink, Patrick Schrauwen
The incidence of obesity and metabolic disease, such as type 2 diabetes mellitus (T2D), are rising globally. Dietary lipid over-supply leads to lipid accumulation at ectopic sites, such as skeletal muscle. Ectopic lipid storage is highly correlated with insulin resistance and T2D, likely due to a loss of metabolic flexibility - the capacity to switch between fat and glucose oxidation upon insulin stimulation - and cellular dysfunction because of lipotoxicity. However, muscle lipid levels are also elevated in endurance trained athletes, presenting a paradoxical phenotype of increased intramuscular lipids along with high insulin sensitivity - the "athletes' paradox"...
January 13, 2018: Journal of Internal Medicine
https://www.readbyqxmd.com/read/29330079/impact-of-platelet-transfusion-on-intracerebral-hemorrhage-ich-in-patients-on-antiplatelet-therapy-an-analysis-based-on-ich-score
#3
Gregory D Arnone, Prateek Kumar, Matt C Wonais, Darian R Esfahani, Sally A Campbell-Lee, Fady T Charbel, Sepideh Amin-Hanjani, Ali Alaraj, Andreea Seicean, Ankit I Mehta
OBJECTIVE: Platelet transfusions for intracerebral hemorrhage (ICH) patients on antiplatelet therapy (APT) remain controversial. Diverging past research and differences in platelet preparation warrant further investigation of this topic. In this study, the association between platelet transfusion and clinical outcomes of ICH is investigated in patients matched by ICH score, a validated predictor of mortality. METHODS: A consecutive review of all patients from 2012 to 2015 with non-traumatic ICH was performed...
January 9, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29327140/children-s-experiences-of-congenital-heart-disease-a-systematic-review-of-qualitative-studies
#4
REVIEW
Lauren S H Chong, Dominic A Fitzgerald, Jonathan C Craig, Karine E Manera, Camilla S Hanson, David Celermajer, Julian Ayer, Nadine A Kasparian, Allison Tong
We aimed to describe the experiences of children and adolescents with congenital heart disease (CHD). Electronic databases were searched until August 2016. Qualitative studies of children's perspectives on CHD were included. Data was extracted using thematic synthesis. From 44 studies from 12 countries involving 995 children, we identified 6 themes: disrupting normality (denying the diagnosis, oscillating between sickness and health, destabilizing the family dynamic), powerlessness in deteriorating health (preoccupation with impending mortality, vulnerability to catastrophic complications, exhaustion from medical testing), enduring medical ordeals (traumatized by invasive procedures, disappointed by treatment failure, displaced by transition, valuing empathy and continuity in care, overcoming uncertainty with information), warring with the body (losing stamina, distressing inability to participate in sport, distorted body image, testing the limits), hampering potential and goals (feeling disabled, unfair judgment and exclusion, difficulties with academic achievement, limiting attainment and maintenance of life milestones), and establishing one's own pace (demarcating disease from life, determination to survive, taking limitations in their stride, embracing the positives, finding personal enrichment, relying on social or spiritual support)...
January 11, 2018: European Journal of Pediatrics
https://www.readbyqxmd.com/read/29326358/targeted-alpha-therapy-of-mcrpc-with-225actinium-psma-617-swimmer-plot-analysis-suggests-efficacy-regarding-duration-of-tumor-control
#5
Clemens Kratochwil, Frank Bruchertseifer, Hendrik Rathke, Markus Hohenfellner, Frederik L Giesel, Uwe Haberkorn, Alfred Morgenstern
The aim of this evaluation is to identify first indicators regarding the efficacy of 225Ac-PSMA-617 therapy in a retrospectively analyzed group of patients. Methods: Forty patients with metastatic castration-resistant prostate cancer were selected for treatment with 3 cycles of 100 kBq/kgBW 225Ac-PSMA-617 in 2 months intervals. Prostate-specific antigen (PSA) and blood cell count were measured every 4 weeks. Prostate-specific membrane antigen (PSMA)-PET/CT or PSMA-SPECT/CT were used for baseline staging and imaging follow-up at month six...
January 11, 2018: Journal of Nuclear Medicine: Official Publication, Society of Nuclear Medicine
https://www.readbyqxmd.com/read/29322861/community-mobility-after-stroke-a-systematic-review
#6
Steven Wesselhoff, Timothy A Hanke, Christian C Evans
Background Stroke is the leading cause of severe disability and many survivors report long-term physical or cognitive impairments that may impact their ability to achieve community mobility (CM). PURPOSE: To determine the extent to which people with chronic stroke achieve CM compared to age-matched norms or non-neurologically impaired controls. Methods The StrokEDGE outcome measures were searched to identify validated tools that included >25% of items addressing CM. MEDLINE, CINAHL, Google Scholar, PubMed, PEDro and the Cochrane databases were searched from 2001 to 2015 with the identified outcome measures cross-referenced against search terms related to stroke and CM...
January 11, 2018: Topics in Stroke Rehabilitation
https://www.readbyqxmd.com/read/29318752/molecular-firefighting-how-modern-phosphorus-chemistry-can-help-solve-the-flame-retardancy-task
#7
Maria M Velencoso, Alexander Battig, Jens C Markwart, Bernhard Schartel, Frederik Roman Wurm
The ubiquity of polymeric materials in daily life comes at an increased fire risk, and enduring research into efficient flame retardants is the key to ensuring the safety of the populace and material goods from accidental fires. Phosphorus, a versatile and effective element for use in flame retardants, has the potential to supersede halogenated variants still widely used today: current formulations employ a variety of modes of action and methods of implementation, as additives or as reactants, to solve the task of flame retarding polymeric materials...
January 9, 2018: Angewandte Chemie
https://www.readbyqxmd.com/read/29318730/mentorship-in-the-health-professions-a-review
#8
REVIEW
Annette Burgess, Christie van Diggele, Craig Mellis
BACKGROUND: The importance of mentorship within health care training is well recognised. It offers a means to further enhance workforce performance and engagement, promote learning opportunities and encourage multidisciplinary collaboration. There are both career and life benefits associated with mentorship, and it is increasingly recognised as a bidirectional process that benefits both mentors and mentees. Recently, mentoring has been considered an essential step in professional and personal development, particularly in the field of health care...
January 10, 2018: Clinical Teacher
https://www.readbyqxmd.com/read/29299221/cycle-training-using-implanted-neural-prostheses-team-cleveland
#9
John McDaniel, Lisa M Lombardo, Kevin M Foglyano, Paul D Marasco, Ronald J Triolo
Recently our laboratory team focused on training five individuals with complete spinal cord injuries for an overground FES bike race in the 2016 Cybathlon held in Zurich Switzerland. A unique advantage team Cleveland had over other teams was the use of implanted pulse generators that provide more selective activation of muscles compared to standard surface stimulation. The advancements in muscle strength and endurance and ultimately cycling power our pilots made during this training period helped propel our competing pilot to win gold at the Cybathlon and allowed our pilots to ride their bikes outside within their communities...
December 5, 2017: European Journal of Translational Myology
https://www.readbyqxmd.com/read/29289581/physical-exercise-improves-strength-balance-mobility-and-endurance-in-people-with-cognitive-impairment-and-dementia-a-systematic-review
#10
Freddy Mh Lam, Mei-Zhen Huang, Lin-Rong Liao, Raymond Ck Chung, Timothy Cy Kwok, Marco Yc Pang
QUESTION: Does physical exercise training improve physical function and quality of life in people with cognitive impairment and dementia? Which training protocols improve physical function and quality of life? How do cognitive impairment and other patient characteristics influence the outcomes of exercise training? DESIGN: Systematic review with meta-analysis of randomised trials. PARTICIPANTS: People with mild cognitive impairment or dementia as the primary diagnosis...
December 27, 2017: Journal of Physiotherapy
https://www.readbyqxmd.com/read/29283899/-effects-of-mat-pilates-on-physical-functional-performance-of-older-adults-a-meta-analysis-of-randomized-controlled-trials
#11
Roberta Oliveira Bueno de Souza, Liliane de Faria Marcon, Alex Sandro Faria de Arruda, Francisco Luciano Pontes Junior, Ruth Caldeira de Melo
OBJECTIVE: The present meta-analysis aimed to examine evidence from randomized controlled trials in order to determine the effects of mat Pilates on measures of physical functional performance in the elderly. DESIGN: A search was conducted in the MEDLINE/PubMed, Scopus, Scielo and PEDro databases between February and March 2017. Only RCTs that were written in English; included subjects 60 years-old; utilized mat Pilates exercises; included a comparison (control) group; and reported performance-based measures of physical function (balance, flexibility, muscle strength and cardiorespiratory fitness) were included...
December 27, 2017: American Journal of Physical Medicine & Rehabilitation
https://www.readbyqxmd.com/read/29260751/-clinical-efficacy-of-the-immunomodulatory-agent-cycloferon-tablets-in-viral-respiratory-infections-results-of-a-systematic-review-and-meta-analysis
#12
N K Mazina, I V Sheshunov, P V Mazin, V P Mazin, A L Kovalenko, V A Zaplutanov
The authors carried out a systematic review and subsequent meta-analysis of randomized clinical trials evaluating the efficacy of the immunomodulator agent cycloferon as tablets in adults and children with viral respiratory diseases. A total estimate of its clinical efficacy was obtained in terms of compared heterogeneous groups and response variables. The data published in 16 articles were used to calculate the formal parameters of the clinical efficacy of cycloferon (increased absolute and relative benefits, odds ratio (OR); the number of patients needed to be additionally treated with cycloferon to achieve a favorable outcome or to prevent a poor outcome in one patient, etc...
2017: Terapevticheskiĭ Arkhiv
https://www.readbyqxmd.com/read/29260420/physical-characteristics-of-players-within-the-australian-football-league-participation-pathways-a-systematic-review
#13
REVIEW
Jade A Z Haycraft, Stephanie Kovalchik, David B Pyne, Sam Robertson
BACKGROUND: Australian football (AF) players require endurance, strength, speed, and agility to be successful. Tests assessing physical characteristics are commonly used for talent identification; however, their ability to differentiate between players across the Australian Football League's (AFL) participation pathway remains unclear. The objective of this review was to quantify the physical characteristics of male AF players across the AFL participation pathway. METHODS: A search of databases was undertaken...
December 19, 2017: Sports Medicine—Open
https://www.readbyqxmd.com/read/29259804/acute-kidney-injury-associated-with-endurance-events-is-it-a-cause-for-concern-a-systematic-review
#14
L E Hodgson, E Walter, R M Venn, R Galloway, Y Pitsiladis, F Sardat, L G Forni
Introduction: A growing body of evidence suggests even small rises in serum creatinine (SCr) are of considerable clinical relevance. Given that participants in endurance events are exposed to potential (repeated) renal insults, a systematic review was undertaken to collate current evidence for acute kidney injury (AKI), complicating such events. Methods: A systematic review of studies and case reports meeting inclusion criteria on Medline and EMBASE (inception to October 2015)...
2017: BMJ Open Sport & Exercise Medicine
https://www.readbyqxmd.com/read/29249084/return-to-sport-in-athletes-with-midportion-achilles-tendinopathy-a-qualitative-systematic-review-regarding-definitions-and-criteria
#15
REVIEW
Bas Habets, Anke G van den Broek, Bionka M A Huisstede, Frank J G Backx, Robert E H van Cingel
BACKGROUND: Midportion Achilles tendinopathy (AT) can cause long-term absence from sports participation, and shows high recurrence rates. It is important that the decision to return to sport (RTS) is made carefully, based on sharply delimited criteria. Lack of a well-defined definition and criteria hampers the decision to RTS among athletes with AT, and impedes comparison of RTS rates between different studies. OBJECTIVE: The aim of this study was to systematically review the literature for definitions of, and criteria for, RTS in AT research...
December 16, 2017: Sports Medicine
https://www.readbyqxmd.com/read/29246794/is-core-stability-a-risk-factor-for-lower-extremity-injuries-in-an-athletic-population-a-systematic-review
#16
REVIEW
Cedric De Blaiser, Philip Roosen, Tine Willems, Lieven Danneels, Luc Vanden Bossche, Roel De Ridder
OBJECTIVES: To research and summarize the literature regarding the role of core stability as a risk factor in the development of lower extremity injuries in an athletic population. METHODS: Pubmed, Web of Science and Embase were searched in August 2016 to systematically review studies, which related core muscle functioning and core stability to lower extremity injuries. RESULTS: Nine articles were included in the systematic review. Various components of core stability were found to be related to lower extremity musculoskeletal injuries in healthy athletic populations...
August 24, 2017: Physical Therapy in Sport
https://www.readbyqxmd.com/read/29245355/endometriosis-associated-malignant-transformation-in-abdominal-surgical-scar-a-prisma-compliant-systematic-review
#17
Anca Mihailovici, Misgav Rottenstreich, Svetlana Kovel, Ilan Wassermann, Noam Smorgick, Zvi Vaknin
BACKGROUND: Endometriosis-associated malignant transformation in abdominal surgical scar (EAMTAS) is a very rare and aggressive phenomenon. Our current article aims to provide a clinical overview, focusing on risk factors affecting survival. METHODS: We performed a Preferred Reporting Items for Systematic Reviews and Meta-Analyses-compliant systematic review based on prior reviews and case reports regarding the phenomenon published as abstracts in English, from January 1980 to November 2016...
December 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29236278/head-and-neck-surgical-reconstruction-in-operation-iraqi-freedom-and-operation-enduring-freedom-afghanistan-a-systematic-review
#18
Samantha J Mikals, Joshua M Jabaut, Art A Ambrosio
Historically, head and neck injuries constituted 16 to 20% of all nonfatal combat injuries. However, advances in body and vehicle armor in the context of the use of ambushes and improvised explosive devices by enemy combatants have resulted in fewer fatalities from head and neck wounds, and thus the incidence of nonfatal head and neck injuries has risen to as high as 52%. Despite this increase, data regarding specific injury distributions, surgical cases, and approaches to repair are lacking in the current literature...
December 2017: Ear, Nose, & Throat Journal
https://www.readbyqxmd.com/read/29225820/iron-therapy-in-heart-failure-patients-without-anaemia-possible-implications-for-chronic-kidney-disease-patients
#19
REVIEW
Jolanta Malyszko, Stefan D Anker
Iron deficiency anaemia is a global health problem that manifests as fatigue and poor physical endurance. Anaemia can be caused by dietary iron deficiency, blood loss or a combination of poor iron absorption and ineffective iron mobilization in patients with chronic disease. Nephrologists caring for patients with impaired renal function understand that iron treatment is necessary to provide adequate iron for erythropoiesis during the treatment of overt anaemia. However, a less well-understood health problem is iron deficiency, which creates symptoms that overlap with those of anaemia and often occurs in concert with chronic disease...
December 2017: Clinical Kidney Journal
https://www.readbyqxmd.com/read/29223353/late-open-surgical-conversion-after-endovascular-abdominal-aortic-aneurysm-repair
#20
Vinay Kansal, Sudhir Nagpal, Prasad Jetty
INTRODUCTION: Late open surgical conversion following endovascular aneurysm repair (EVAR) may occur more frequently after performing EVAR in anatomy outside the instructions for use (IFU). This study reviews predictors and outcomes of late open surgical conversion for failed EVAR. METHODS: This retrospective cohort study reviewed all EVARs performed at the Ottawa Hospital between January 1999 and May 2015. Open surgical conversions >1 month post EVAR were identified...
December 6, 2017: European Journal of Vascular and Endovascular Surgery
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