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https://www.readbyqxmd.com/read/29141591/the-impact-of-pregnancy-loss-on-men-s-health-and-wellbeing-a-systematic-review
#1
Clemence Due, Stephanie Chiarolli, Damien W Riggs
BACKGROUND: Research indicates that men's psychological and physical health outcomes after pregnancy loss differ from those of women. Our goal was to identify all literature with a focus on men's experiences of pregnancy loss in order to outline current evidence concerning men's wellbeing. METHODS: A systematic review of literature on men and pregnancy loss was undertaken following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA), Joanna Briggs Institute (JBI) and Social Care Institute for Excellence (SCIE) guidelines...
November 15, 2017: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/29137117/a-systematic-review-and-meta-analysis-of-proteomics-literature-on-the-response-of-human-skeletal-muscle-to-obesity-type-2-diabetes-mellitus-t2dm-versus-exercise-training
#2
REVIEW
Kanchana Srisawat, Sam O Shepherd, Paulo J Lisboa, Jatin G Burniston
We performed a systematic review and meta-analysis of proteomics literature that reports human skeletal muscle responses in the context of either pathological decline associated with obesity/T2DM and physiological adaptations to exercise training. Literature was collected from PubMed and DOAJ databases following PRISMA guidelines using the search terms 'proteom*', and 'skeletal muscle' combined with either 'obesity, insulin resistance, diabetes, impaired glucose tolerance' or 'exercise, training'. Eleven studies were included in the systematic review, and meta-analysis was performed on a sub-set (four studies) of the reviewed literature that reported the necessary primary data...
November 11, 2017: Proteomes
https://www.readbyqxmd.com/read/29127759/is-irisin-the-new-player-in-exercise-induced-adaptations-or-not-a-2017-update
#3
REVIEW
Ioannis G Fatouros
Irisin is produced by a proteolytic cleavage of fibronectin type III domain-containing protein 5 (FNDC5) and has emerged as a potential mediator of exercise-induced energy metabolism. The purpose of this study was to review the results of studies that investigated irisin responses to acute and chronic exercise and provide an update. A comprehensive search in the databases of MEDLINE was performed (74 exercise studies). The focus of the analysis was on data concerning FNDC5 mRNA expression in skeletal muscle and circulating irisin concentration relatively to exercise mode, intensity, frequency and duration and the characteristics of the sample used...
November 11, 2017: Clinical Chemistry and Laboratory Medicine: CCLM
https://www.readbyqxmd.com/read/29113535/effects-of-erythropoietin-abuse-on-exercise-performance
#4
Paolo Sgrò, Massimiliano Sansone, Andrea Sansone, Francesco Romanelli, Luigi Di Luigi
The present review provides a comprehensive overview on the erythropoietic and non-erythropoietic effects of rHuEpo on human sport performance, paying attention to quantifying numerically how rHuEpo affects exercise performance and describing physiological changes regarding the most important exercise variables. Much attention has been paid to treatment schedules, in particular, to assess the effects of microdoses of rHuEpo and the prolonged effects on sport performance following withdrawal. Moreover, the review takes into account non-erythropoietic ergogenic effects of rHuEpo, including cognitive benefits of rHuEpo...
November 8, 2017: Physician and Sportsmedicine
https://www.readbyqxmd.com/read/29112054/lower-extremity-stiffness-considerations-for-testing-performance-enhancement-and-injury-risk
#5
Jon Brazier, Sean Maloney, Chris Bishop, Paul J Read, Anthony N Turner
Brazier, J, Maloney, S, Bishop, C, Read, PJ, and Turner, AN. Lower extremity stiffness: considerations for testing, performance enhancement, and injury risk. J Strength Cond Res XX(X): 000-000, 2017-Force-deformation characteristics of the lower limb have been associated with athletic performance and may modulate the risk of injury. Despite these known associations, measurements of lower extremity stiffness are not commonly administered by strength and conditioning coaches. This review provides an overview of the available literature pertaining to the effects of lower extremity stiffness on physical performance and injury risk...
November 1, 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/29110907/what-is-the-impact-of-professional-nursing-on-patients-outcomes-globally-an-overview-of-research-evidence
#6
REVIEW
Samantha Coster, Mary Watkins, Ian J Norman
BACKGROUND: Nursing is an integral part of all healthcare services, and has the potential of having a wide and enduring impact on health outcomes for a global ageing population. Over time nurses have developed new roles and assumed greater responsibilities. It is increasingly important to demonstrate the safety and overall impact of nurses' practice through research, to support the case for greater investment and development of nursing services around the world. OBJECTIVE: To provide an overview of existing research evidence on the impact of nursing on patient outcomes, identify gaps in evidence, and point to future priorities for global research...
October 19, 2017: International Journal of Nursing Studies
https://www.readbyqxmd.com/read/29100631/drug-cues-conditioned-reinforcement-and-drug-seeking-the-sequelae-of-a-collaborative-venture-with-athina-markou
#7
REVIEW
Barry J Everitt
Athina Markou spent a research period in my laboratory, then in the Department of Anatomy in Cambridge University, in 1991 to help us establish a cocaine-seeking procedure. Thus we embarked on developing a second-order schedule of intravenous cocaine reinforcement to investigate the neural basis of the pronounced effects of cocaine-associated conditioned stimuli on cocaine seeking. This brief review summarizes the fundamental aspects of cocaine seeking measured using this approach and the importance of the methodology in enabling us to define the neural mechanisms and circuitry underlying conditioned reinforcement and cocaine, heroin, and alcohol seeking...
September 25, 2017: Biological Psychiatry
https://www.readbyqxmd.com/read/29098657/post-exercise-ingestion-of-carbohydrate-protein-and-water-a-systematic-review-and-meta-analysis-for-effects-on-subsequent-athletic-performance
#8
REVIEW
Danielle McCartney, Ben Desbrow, Christopher Irwin
BACKGROUND: Athletes may complete consecutive exercise sessions with limited recovery time between bouts (e.g. ≤ 4 h). Nutritional strategies that optimise post-exercise recovery in these situations are therefore important. OBJECTIVE: This two-part review investigated the effect of consuming carbohydrate (CHO) and protein with water (W) following exercise on subsequent athletic (endurance/anaerobic exercise) performance. DATA SOURCES: Studies were identified by searching the online databases SPORTDiscus, PubMed, Web of Science and Scopus...
November 2, 2017: Sports Medicine
https://www.readbyqxmd.com/read/29098620/clinical-evidence-of-exercise-benefits-for-stroke
#9
Peipei Han, Wen Zhang, Li Kang, Yixuan Ma, Liyuan Fu, Liye Jia, Hairui Yu, Xiaoyu Chen, Lin Hou, Lu Wang, Xing Yu, Masahiro Kohzuki, Qi Guo
Even though stroke is the third, not the first, most common cause of disability-adjusted life years in developed countries, it is one of the most expensive to treat. Part of the expense is due to secondary problems in the post-stroke period including: cognition, memory, attention span, pain, sensation loss, psychological issues, and problems with mobility and balance. Research has identified that exercise has both positive physical and psychosocial effects for post-stroke patients. Therefore, this scientific statement provides an overview on exercise rehabilitation for post-stroke patients...
2017: Advances in Experimental Medicine and Biology
https://www.readbyqxmd.com/read/29094622/long-term-effects-of-internet-supported-cognitive-behaviour-therapy
#10
Gerhard Andersson, Alexander Rozental, Roz Shafran, Per Carlbring
Internet-supported and therapist-guided cognitive behaviour therapy (ICBT) is effective for a range of problems in the short run, but less is known about the long-term effects with follow-ups of two years or longer. Areas covered: This paper reviews studies in which the long-term effects of guided ICBT were investigated. Following literature searches in PubMed and other sources meta-analytic statistics were calculated for 14 studies involving a total of 902 participants, and an average follow-up period of three years...
November 2, 2017: Expert Review of Neurotherapeutics
https://www.readbyqxmd.com/read/29089897/acute-and-chronic-effects-of-endurance-running-on-inflammatory-markers-a-systematic-review
#11
Edilberto S Barros, Dahan C Nascimento, Jonato Prestes, Otávio T Nóbrega, Claúdio Córdova, Fernando Sousa, Daniel A Boullosa
In order to understand the effect of endurance running on inflammation, it is necessary to quantify the extent to which acute and chronic running affects inflammatory mediators. The aim of this study was to summarize the literature on the effects of endurance running on inflammation mediators. Electronic searches were conducted on PubMED and Science Direct with no limits of date and language of publication. Randomized controlled trials (RCTs) and non-randomized controlled trials (NRCTs) investigating the acute and chronic effects of running on inflammation markers in runners were reviewed by two researchers for eligibility...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/29081381/inflammageing-and-metaflammation-the-yin-and-yang-of-type-2-diabetes
#12
REVIEW
Francesco Prattichizzo, Valeria De Nigris, Rosangela Spiga, Elettra Mancuso, Lucia La Sala, Roberto Antonicelli, Roberto Testa, Antonio Domenico Procopio, Fabiola Olivieri, Antonio Ceriello
Type 2 diabetes mellitus (T2DM) is characterised by chronic low-grade inflammation, recently referred to as 'metaflammation', a relevant factor contributing to the development of both diabetes and its complications. Nonetheless, 'canonical' anti-inflammatory drugs do not yield satisfactory results in terms of prevention of diabetes progression and of cardiovascular events, suggesting that the causal mechanisms fostering metaflammation deserve further research to identify new druggable targets. Metaflammation resembles ageing-induced low-grade inflammation, previously referred to as inflammageing, in terms of clinical presentation and the molecular profile, pointing to a common aetiology for both conditions...
October 31, 2017: Ageing Research Reviews
https://www.readbyqxmd.com/read/29079169/utilizing-dual-mobility-components-for-first-time-revision-total-hip-arthroplasty-for-instability
#13
Jeffrey K Lange, Sara K Spiro, Geoffrey H Westrich
BACKGROUND: Dislocation following total hip arthroplasty (THA) remains a significant clinical problem. Few studies have focused on the use of dual mobility (DM) components in the setting of first-time revision for instability following THA. Here, we investigate patient outcomes following first-time revision THA with DM components for a diagnosis of instability. METHODS: Institution-wide revision THAs using DM components performed between 2010 and 2013 were identified...
September 23, 2017: Journal of Arthroplasty
https://www.readbyqxmd.com/read/29072101/understanding-mitochondrial-biogenesis-through-energy-sensing-pathways-and-its-translation-in-cardio-metabolic-health
#14
Abhijit Nirwane, Anuradha Majumdar
Mitochondria play a pivotal role in physiological energy governance. Mitochondrial biogenesis comprises growth and division of pre-existing mitochondria, triggered by environmental stressors such as endurance exercise, caloric restriction, cold exposure and oxidative stress. For normal physiology, balance between energy intake, storage and expenditure is of utmost important for the coordinated regulation of energy homeostasis. In contrast, abnormalities in these regulations render the individual susceptible to cardiometabolic disorders...
October 26, 2017: Archives of Physiology and Biochemistry
https://www.readbyqxmd.com/read/29072025/does-small-sided-games-training-improve-physical-fitness-and-specific-skills-for-team-sports-a-systematic-review-with-meta-analysis
#15
Amri Hammami, Tim J Gabbett, Maamer Slimani, Ezdine Bouhlel
INTRODUCTION: This paper aimed to systematically review and meta-analyse the training effects of small-sided games (SSG) on physical fitness and specific skills related to team sport according to the level of play and the period of the season. EVIDENCE ACQUISITION: The search covered the following electronic databases (PubMed, Google Scholar, and ScienceDirect). The publications' search period ranged from 2000 to 2016. The terms (small- sided game, training, skill-based game, aerobic fitness, sprint, agility, jump and team sports) were used either singularly or combined in a systematic sequence...
October 24, 2017: Journal of Sports Medicine and Physical Fitness
https://www.readbyqxmd.com/read/29071250/defining-disease-modifying-therapy-for-alzheimer-s-disease
#16
J Cummings, N Fox
BACKGROUND: Disease-modifying therapies (DMTs) are urgently needed to treat the growing number of individuals with Alzheimer's disease (AD) or at immanent risk for AD. A definition of DMT is required to facilitate the process of DMT drug development. PROCESS: This is a review of the state of the science with regard to definition and development of DMTs. RESULTS: A DMT is as an intervention that produces an enduring change in the clinical progression of AD by interfering in the underlying pathophysiological mechanisms of the disease process that lead to cell death...
2017: Journal of Prevention of Alzheimer's Disease
https://www.readbyqxmd.com/read/29071072/effect-of-high-flow-nasal-therapy-during-acute-aerobic-exercise-in-patients-with-chronic-obstructive-pulmonary-disease-after-exacerbation-protocol-for-a-randomised-controlled-cross-over-trial
#17
Guillaume Prieur, Clement Medrinal, Yann Combret, Aurora Robledo Quesada, Fabrice Prieur, Jean Quieffin, Jean Christian Borel, Gregory Reychler
INTRODUCTION: Early pulmonary rehabilitation is recommended after a severe exacerbation of chronic obstructive pulmonary disease (COPD). However, this is difficult to implement, particularly for exercise training. High-flow nasal therapy (HFNT) may reduce the work of breathing and dyspnoea and may improve exercise tolerance. METHODS AND ANALYSIS: This is a single-centre, prospective, controlled, randomised, cross-over study. Eligible patients will have a diagnosis of COPD (postbronchodilator forced expiratory volume in 1 s/forced vital capacity ratio of <0...
2017: BMJ Open Respiratory Research
https://www.readbyqxmd.com/read/29064055/towards-rectifying-performance-at-the-molecular-scale
#18
REVIEW
Guang-Ping Zhang, Zhen Xie, Yang Song, Gui-Chao Hu, Chuan-Kui Wang
Molecular diode, proposed by Mark Ratner and Arieh Aviram in 1974, is the first single-molecule device investigated in molecular electronics. As a fundamental device in an electric circuit, molecular diode has attracted an enduring and extensive focus during the past decades. In this review, the theoretical and experimental progresses of both charge-based and spin-based molecular diodes are summarized. For the charge-based molecular diodes, the rectifying properties originated from asymmetric molecules including D-σ-A, D-π-A, D-A, and σ-π type compounds, asymmetric electrodes, asymmetric nanoribbons, and their combination are analyzed...
October 24, 2017: Topics in Current Chemistry (Journal)
https://www.readbyqxmd.com/read/29063207/cardiorespiratory-fitness-and-cardiac-autonomic-function-in-diabetes
#19
REVIEW
Martin Röhling, Alexander Strom, Gidon J Bönhof, Michael Roden, Dan Ziegler
PURPOSE OF REVIEW: This review summarizes the current knowledge on the relationship of physical activity, exercise, and cardiorespiratory fitness (CRF) with cardiovascular autonomic neuropathy (CAN) based on epidemiological, clinical, and interventional studies. RECENT FINDINGS: The prevalence of CAN increases with age and duration of diabetes. Further risk factors for CAN comprise poor glycemic control, dyslipidemia, abdominal obesity, hypertension, and the presence of diabetic complications...
October 23, 2017: Current Diabetes Reports
https://www.readbyqxmd.com/read/29061342/pharmacological-targeting-of-exercise-adaptations-in-skeletal-muscle-benefits-and-pitfalls
#20
REVIEW
Martin Weihrauch, Christoph Handschin
Exercise exerts significant effects on the prevention and treatment of many diseases. However, even though some of the key regulators of training adaptation in skeletal muscle have been identified, this biological program is still poorly understood. Accordingly, exercise-based pharmacological interventions for many muscle wasting diseases and also for pathologies that are triggered by a sedentary lifestyle remain scarce. The most efficacious compounds that induce muscle hypertrophy or endurance are hampered by severe side effects and are classified as doping...
October 20, 2017: Biochemical Pharmacology
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