keyword
https://read.qxmd.com/read/38262496/whole-exome-sequencing-approach-for-identification-of-the-molecular-etiology-in-pediatric-patients-with-hematuria
#21
JOURNAL ARTICLE
Jinying Wu, Yaqiong Cui, Tao Liu, Chunyu Gu, Ximeng Ma, Changshun Yu, Yingzi Cai, Jianbo Shu, Wenhong Wang, Chunquan Cai
BACKGROUND: Hematuria is a common condition in clinical practice of pediatric patients. It is related to a wide spectrum of disorders and has high heterogeneity both clinically and genetically, which contributes to challenges of diagnosis and lead many pediatric patients with hematuria not to receive accurate diagnosis and early management. METHODS: In this single center study, 42 children with hematuria were included in Tianjin Children' Hospital between 2019 and 2020...
January 21, 2024: Clinica Chimica Acta; International Journal of Clinical Chemistry
https://read.qxmd.com/read/38259681/emergency-angioembolization-for-life-threatening-hemorrhage-in-wilms-tumor
#22
Areej Salim, Sajid Ali, Muhammad Ali Sheikh, Tariq Latif, Islah Ud Din
INTRODUCTION: Renal artery embolization has been used in a palliative fashion for symptomatic relief of hematuria or flank pain in unresectable renal cell carcinoma in adults. There is limited data on the use of embolization for actively bleeding and unresectable tumors in the oncological pediatric population. CASE DESCRIPTION: A previously healthy 5-year-old boy with no significant past medical or surgical history presented to the clinic with gradually worsening abdominal distension associated with occasional abdominal pain, gross hematuria, and lethargy for four months...
2024: Journal of cancer & allied specialties
https://read.qxmd.com/read/38225439/childhood-onset-iga-nephropathy-is-long-term-recovery-possible
#23
JOURNAL ARTICLE
Luca Antonucci, Laura Fuiano, Antonio Gargiulo, Alessandra Gianviti, Andrea Onetti Muda, Francesca Diomedi Camassei, Marina Vivarelli, Francesco Emma
BACKGROUND: IgA nephropathy (IgAN) is the most common glomerulonephritis worldwide. While studies have primarily focused on identifying risk factors for disease progression, very few data exist on the likelihood of achieving complete recovery from the disease. METHODS: We conducted a single-center retrospective study on all consecutive patients with biopsy-proven IgAN diagnosed between 1986 and 2018 in our pediatric center. Biopsies were classified according to the MEST-C Oxford classification score...
January 16, 2024: Pediatric Nephrology
https://read.qxmd.com/read/38217079/in-utero-tumor-development-and-identification-of-ctnnb1-mutation-in-a-newborn-case-of-ossifying-renal-tumor-of-infancy
#24
EDITORIAL
Shin Kasai, Minori Tamai, Eiji Sugihara, Naoki Oishi, Kyoko Hinata, Koshi Akahane, Kumiko Goi, Yuko Hata, Tetsuo Kondo, Takahiko Mitsui, Mio Tanaka, Takeshi Inukai
No abstract text is available yet for this article.
January 12, 2024: Pediatric Blood & Cancer
https://read.qxmd.com/read/38212419/pediatric-urogenital-schistosomiasis-diagnosed-in-france
#25
JOURNAL ARTICLE
Lucas Percheron, Claire Leblanc, Tim Ulinski, Marc Fila, Denis Malvy, Justine Bacchetta, Vincent Guigonis, Cecile Debuisson, Elise Launay, Edouard Martinez, Aurelie Morand, Stéphane Decramer, Joost-Peter Schanstra, Antoine Berry
BACKGROUND: Schistosomiasis affects approximately 230 million people worldwide. There is an increased incidence of schistosomiasis cases in France acquired from outside the country. This increases the risk of schistosomiasis outbreaks as observed in Corsica. Clinicians from non-endemic regions are not accustomed to diagnosing and managing this pathology. The objective of this study is to provide a better description of the clinical and paraclinical characteristics and disease evolution of affected children...
January 12, 2024: Pediatric Nephrology
https://read.qxmd.com/read/38192908/acquired-thrombotic-thrombocytopenic-purpura-in-the-presence-of-a-urinary-tract-infection-a-rare-pediatric-case
#26
Monica Karas, Andrew M Joseph, Omama Ahmad, Jose M Cardenas
Thrombotic thrombocytopenic purpura (TTP) is a type of microangiopathic hemolytic anemia that rarely presents in the pediatric population. This life-threatening disorder manifests as severe consumptive thrombocytopenia and disseminated micro-thromboemboli, leading to organ ischemia. Here, we present a case of an acute first-time episode of acquired TTP in a 17-year-old African American female with a past medical history of obesity, recurrent urinary tract infections, and dysfunctional uterine bleeding managed with oral contraceptives...
December 2023: Curēus
https://read.qxmd.com/read/38185850/analysis-of-the-therapeutic-efficacy-of-laparoscopic-treatment-for-fibroepithelial-polyps-of-the-ureter-in-children
#27
JOURNAL ARTICLE
Chengpin Tao, Yongsheng Cao, Changkun Mao
OBJECTIVE: The aim of this study is to assess the efficacy and safety of laparoscopic surgery in the treatment of pediatric ureteral fibroepithelial polyps patients. Our research aims to evaluate the clinical outcomes of the surgery, including postoperative symptom relief, improvement in kidney function, and the risk of postoperative complications. METHODS: The clinical records of 34 patients who underwent ureteral polyp surgery at the Department of Urology in Anhui Children's Hospital between May 2014 and February 2023 were retrospectively analyzed...
January 7, 2024: Journal of Endourology
https://read.qxmd.com/read/38166426/recurrent-anemia-in-10-year-old-with-rash-joint-pain-and-hematuria
#28
JOURNAL ARTICLE
Joy A Stouffer, Shreya Raavicharla, Pooja Gajulapalli, Hannah A Miller, Megan Lo, Clifton C Lee
No abstract text is available yet for this article.
January 3, 2024: Clinical Pediatrics
https://read.qxmd.com/read/38148127/long-term-outcomes-and-associated-prognostic-risk-factors-of-childhood-onset-lupus-nephritis
#29
JOURNAL ARTICLE
Eujin Park, Jiwon Jung, Jeesu Min, Hyeonju Lee, Min Ji Park, Ji Yeon Song, Ji Hyun Kim, Kyung Mi Jang, Eun Mi Yang, Yo Han Ahn, Min Hyun Cho, Joo Hoon Lee, Young Seo Park, Soon Chul Kim, Se Jin Park, Jung Won Lee, Kee Hyuck Kim, Ki Soo Pai, Hee Gyung Kang, Seong Heon Kim
BACKGROUND: This study investigated the clinical characteristics and kidney outcomes of childhood-onset lupus nephritis (LN), and risk factors associated with prognosis. METHODS: We enrolled 216 patients with histologically diagnosed LN during childhood. The Korean Society of Pediatric Nephrology organized a retrospective cohort study of childhood-onset LN in 13 major pediatric nephrology centers in South Korea. RESULTS: The mean age at kidney biopsy was 13...
December 18, 2023: Kidney Research and Clinical Practice
https://read.qxmd.com/read/38143723/inflammatory-myofibroblastic-tumor-of-the-bladder-in-an-adolescent-case-report
#30
Linda Guan, Azeem Khan, Amy Zhou, Hubert S Swana
Inflammatory myofibroblastic tumors of the bladder (IMTB) are rare neoplasms that can occur in children. These tumors have uncertain malignant potential and can present similarly to bladder sarcomas. It is important to differentiate between IMTB and bladder sarcomas using a careful immunohistochemical approach. We report a case of IMTB in a 12-year-old girl who presented with presyncope and gross hematuria. IMTB was diagnosed through immunohistochemical analysis, and clinical improvement was observed after resection of the tumor...
January 2024: Urology Case Reports
https://read.qxmd.com/read/38142361/clinical-predictors-of-steroid-resistance-in-childhood-nephrotic-syndrome
#31
JOURNAL ARTICLE
Neslihan Cicek, Nurdan Yıldız, Sercin Guven, Mehtap Kaya, Ibrahim Gokce, Harika Alpay
We aimed to evaluate the clinical parameters, histopathological findings of nephrotic syndrome (NS) patients, and independent factors predicting steroid resistance in a single tertiary center. One hundred and sixty-two children (57 girls and 105 boys) with NS who were followed between 1998 and 2018 were analyzed in this retrospective cohort. The median (interquartile range; range) age and follow-up time were 4.9 (5.7; 0.1-16.8) and 5.5 (5.4; 0.1-20.3) years. A total of 82.7% of the patients were steroid-sensitive nephrotic syndrome (SSNS) and 17...
December 24, 2023: Clinical Pediatrics
https://read.qxmd.com/read/38084552/renal-oncocytoma-in-a-13-year-old-girl-a-case-report-and-literature-review
#32
Xia Wei, Yizhen Wang, Yuan Fang, Lian Chen
Renal oncocytoma is a benign renal neoplasm which has mostly been reported in adults. Occurrence in children is infrequent. To date, there are only six pediatric cases of renal oncocytoma reported previously. Herein, we report a 13-year-old girl presented with hematuria for a week. Abdominal computed tomography showed a well-defined heterogeneous solid mass with a stellate central scar in the left kidney. The patient underwent a nephron sparing surgery. Histopathological and immunohistochemical findings confirmed the diagnosis of renal oncocytoma...
2023: Indian Journal of Pathology & Microbiology
https://read.qxmd.com/read/38084545/two-case-reports-of-mixed-epithelial-and-stromal-renal-tumor-of-kidney-in-children-and-literature-review-analysis
#33
Xia Wei, Yizhen Wang, Yuan Fang, Lian Chen
Mixed epithelial and stromal tumor of the kidney (MESTK) occurs almost exclusively in perimenopausal women while rarely in children. Only five pediatric patients have been described previously. Herein, we report a girl and a boy with MESTK, aged 3- and 4-years-old, respectively. The two patients presented with hematuria or an abdominal mass. Histologically, the tumors were both composed of epithelial and stromal elements. Immunohistochemical staining of tumor cells expressed epithelial and mesenchymal component markers...
2023: Indian Journal of Pathology & Microbiology
https://read.qxmd.com/read/38073338/causes-of-death-among-people-with-myelomeningocele-a-multi-institutional-47-year-retrospective-study
#34
MULTICENTER STUDY
Konrad M Szymanski, Cyrus M Adams, Mohammad Y Alkawaldeh, Paul F Austin, Robin M Bowman, Heidi Castillo, Jonathan Castillo, David I Chu, Carlos R Estrada, Michele Fascelli, Dominic C Frimberger, Patricio C Gargollo, Dawud G Hamdan, Sarah L Hecht, Betsy Hopson, Douglas A Husmann, Micah A Jacobs, Andrew E MacNeily, Daryl J McLeod, Peter D Metcalfe, Theresa Meyer, Rosalia Misseri, Joseph O'Neil, Adam J Rensing, Jonathan C Routh, Kyle O Rove, Kathleen J Sawin, Bruce J Schlomer, Isaac Shamblin, Rebecca L Sherlock, Gennady Slobodov, Jennifer Stout, Stacy T Tanaka, Dana A Weiss, John S Wiener, Hadley M Wood, Elizabeth B Yerkes, Jeffrey Blount
PURPOSE: This study aimed to analyze organ system-based causes and non-organ system-based mechanisms of death (COD, MOD) in people with myelomeningocele (MMC), comparing urological to other COD. METHODS: A retrospective review was performed of 16 institutions in Canada/United States of non-random convenience sample of people with MMC (born > = 1972) using non-parametric statistics. RESULTS: Of 293 deaths (89% shunted hydrocephalus), 12% occurred in infancy, 35% in childhood, and 53% in adulthood (documented COD: 74%)...
2023: Journal of Pediatric Rehabilitation Medicine
https://read.qxmd.com/read/38065912/clinical-value-of-ultrasound-in-adult-wilms-tumor-patient-with-uremia-a-case-report-and-literature-review
#35
REVIEW
Jing-Jing Zhang, Li-Fei Yang, Yi-Zhen Zhang, Xiao-Hong Xie
RATIONALE: Wilms' tumor (WT) is the most common pediatric kidney malignancy and is rarely found in adults. Nonspecific clinical symptoms and imaging features often lead to delayed diagnosis or misdiagnosis of adult WT, resulting in poor clinical outcomes. Ultrasound (US), as an efficient and noninvasive examination method, has been widely used in clinical diagnosis and treatment. Therefore, various US evidence is meaningful to improve understanding of adult WT characteristics in ultrasound...
December 8, 2023: Medicine (Baltimore)
https://read.qxmd.com/read/38063508/renal-function-impairment-in-children-with-congenital-cytomegalovirus-infection-a-cross-sectional-study
#36
JOURNAL ARTICLE
María Ríos-Barnés, Eneritz Velasco-Arnaiz, Clàudia Fortuny, Marta Benavides, Fernando Baquero-Artigao, Oihana Muga, Rut Del Valle, Marie Antoinette Frick, Xavier Bringué, Susana Herrero, Javier Vilas, Almudena Alonso-Ojembarrena, Laura Castells-Vilella, Pablo Rojo, Daniel Blázquez-Gamero, Cristina Esteva, Emilia Sánchez, Ana Alarcón, Antoni Noguera-Julian
BACKGROUND: We aimed to determine the prevalence and severity of glomerular and tubular renal dysfunction by means of urinalysis in infants and toddlers with congenital cytomegalovirus infection (cCMV) and their association with cCMV disease, viruria and antiviral treatment. METHODS: This cross-sectional study was done using the Spanish Registry of Congenital Cytomegalovirus Infection. First-morning urine samples were collected from January 2016 to December 2018 from patients <5 years old enrolled in Spanish Registry of Congenital Cytomegalovirus Infection...
March 1, 2024: Pediatric Infectious Disease Journal
https://read.qxmd.com/read/38027297/single-port-plus-one-robot-assisted-laparoscopic-modified-lich-gregoir-direct-nipple-ureteral-extravesical-reimplantation-in-children-with-a-primary-obstructive-megaureter
#37
JOURNAL ARTICLE
Yufeng He, Shan Lin, Xinru Xu, Shaohua He, Huihuang Xu, Guangxu You, Jianglong Chen, Di Xu
PURPOSE: To introduce a new technique of single-port-plus-one robotic laparoscopic-modified Lich-Gregoir direct nipple ureteral extravesical reimplantation and ascertain its validity in the treatment of pediatric primary obstructive megaureter. METHODS: Between January 2021 and November 2021, we retrospectively analyzed the clinical data of 12 children with primary obstructive megaureter who were admitted to the Department of Pediatric Surgery of Fujian Provincial Hospital...
2023: Frontiers in Pediatrics
https://read.qxmd.com/read/37981541/retrograde-intrarenal-surgery-for-renal-stones-is-it-a-safe-and-effective-option-in-preschool-children
#38
JOURNAL ARTICLE
Claudia Gatti, Elisa Cerchia, Marcello Della Corte, Massimo Catti, Francesca Caravaggi, Davide Campobasso, Pietro Granelli, Simona Gerocarni Nappo, Stefania Ferretti
INTRODUCTION: Few studies in the literature describe the Retrograde Intra-Renal Surgery (RIRS) outcome in preschool children. We evaluated the feasibility, stone-free rate and complications of RIRS in preschool children at two European tertiary care centres of Pediatric Urology. MATERIAL AND METHODS: The retrospective study includes all children undergone RIRS for stones <25 mm from 2017 to 2022. Patients were divided into Group 1 <5 years (G1) and Group 2 >5 years (G2)...
October 28, 2023: Journal of Pediatric Surgery
https://read.qxmd.com/read/37970146/multisystem-inflammatory-syndrome-in-children-experience-from-october-2020-to-january-2021-at-a-tertiary-hospital-in-navi-mumbai-india
#39
JOURNAL ARTICLE
Priyanka S Amonkar, Suhas N Kharche, Amol A Madave, Jeetendra B Gavhane
Although presentation of multisystem inflammatory syndrome (MIS-C) in children is typically with fever and symptoms like diarrhea, vomiting, rash, conjunctival injection, or shock, the spectrum of associated multisystem involvement is wide. Here, we present an account of patients with MIS-C that presented at a tertiary hospital in Navi Mumbai, India in the latter half of the pandemic from October 2020 to January 2021. We retrospectively studied the clinical features of 12 patients satisfying World Health Organization criteria for MIS-C...
December 2023: Journal of Pediatric Intensive Care
https://read.qxmd.com/read/37943374/acute-glomerulonephritis-with-concurrent-suspected-bacterial-pneumonia-is-it-the-tip-of-the-iceberg
#40
JOURNAL ARTICLE
Shimrit Tzvi-Behr, Yaacov Frishberg, Orli Megged, Jenny Weinbrand-Goichberg, Rachel Becher-Cohen, Hadass Terespolsky, Choni Rinat, Sapir Choshen, Efrat Ben-Shalom
BACKGROUND: Post infectious glomerulonephritis is the most common glomerulopathy in children, occurring several weeks after nephritogenic streptococcal throat or skin infection. Reports of acute glomerulonephritis (AGN) occurring during active bacterial pneumonia in children are rare. The aim of this study was to evaluate the incidence of AGN concurrent with bacterial pneumonia in children. METHODS: We reviewed records of all children admitted with a diagnosis of pneumonia to the pediatric department in a single tertiary medical center between January 2015 and April 2023...
November 9, 2023: Pediatric Nephrology
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