keyword
MENU ▼
Read by QxMD icon Read
search

colonic polyps

keyword
https://www.readbyqxmd.com/read/28340209/a-novel-pten-mutation-associated-with-colonic-ganglioneuromatous-polyps
#1
Umair Masood, Natalie Pavelock, Anuj Sharma, Robert Roger Lebel, Anand Gupta, Uma Murthy
No abstract text is available yet for this article.
March 17, 2017: QJM: Monthly Journal of the Association of Physicians
https://www.readbyqxmd.com/read/28331902/cold-snare-polypectomy-for-non-pedunculated-colon-polyps-greater-than-1%C3%A2-cm
#2
Cyrus Piraka, Ahmed Saeed, Akbar K Waljee, Ajish Pillai, Ryan Stidham, B Joseph Elmunzer
Background and study aims Colonic polyps > 1 cm in size are commonly managed using hot polypectomy techniques. The most frequent adverse events (delayed bleeding, post-polypectomy syndrome, and perforation) are related to electrocautery-induced injury. We hypothesized that cold resection of large polyps may have similar efficacy and improved safety compared to hot polypectomy. Our aims were to evaluate efficacy and safety of piecemeal cold snare resection of colonic polyps > 1 cm. Patients and methods Patients undergoing lift and piecemeal cold snare polypectomy of non-pedunculated colon polyps > 1 cm from October 2013 to September 2015 were identified retrospectively...
March 2017: Endoscopy International Open
https://www.readbyqxmd.com/read/28328936/polyp-detection-rate-in-transverse-and-sigmoid-colon-significantly-increases-with-longer-withdrawal-time-during-screening-colonoscopy
#3
Kazuhiro Kashiwagi, Nagamu Inoue, Toshifumi Yoshida, Rieko Bessyo, Kazuaki Yoneno, Hiroyuki Imaeda, Haruhiko Ogata, Takanori Kanai, Yoshinori Sugino, Yasushi Iwao
BACKGROUND: The guidelines for colonoscopy present withdrawal time (WT) and adenoma detection rate (ADR) as the quality indicator. The purpose of this retrospective study is to analyze the predicting factors with polyp detection rate (PDR) as a surrogate for ADR by using comprehensive health checkup data, and assess the correlation between PDR per each colonic segment and WT, and factors influencing WT. METHODS: One thousand and thirty six consecutive health checkup cases from April 2015 to March 2016 were enrolled in this study, and 880 subjects who undertook colonoscopy without polyp removal or biopsy were divided into the two groups (polyp not detected group vs polyp detected group)...
2017: PloS One
https://www.readbyqxmd.com/read/28325889/hypofibrinogenemia-caused-by-hemocoagulase-after-colon-polyps-excision
#4
Hai-Bo Zhou
BACKGROUND In patients with large colon polyps, late-onset bleeding may be more likely to occur because of the larger cutting surface. In these patients, hemostatic agents may be applied to prevent the late-onset bleeding. A total of 7 patients developed hypofibrinogenemia caused by hemocoagulase following excision of colon polyps in our center from November to December 2015. CASE REPORT Seven patients underwent excision of colon polyps in our center from November to December 2015. The cutting face was large in these patients after surgery; therefore, hemocoagulase was used to prevent potential late-onset bleeding...
March 22, 2017: American Journal of Case Reports
https://www.readbyqxmd.com/read/28325827/sessile-serrated-polyps-and-colon-cancer-prevention
#5
Shahrooz Rashtak, Rafaela Rego, Seth R Sweetser, Frank A Sinicrope
Evidence suggests that up to one fifth of colorectal carcinomas (CRC) develop from serrated polyps, named for their pattern of colonic crypts, and include the sessile serrated adenoma/polyp (SSA/P) that has malignant potential. SSA/Ps are typically located in the proximal colon and have molecular features of hypermethylation of CpG islands in gene promoters and activating point mutations (V600E) in the BRAF oncogene. Both of these features are seen in sporadic CRCs with microsatellite instability (MSI) which is potentially consistent with an origin of these cancers from precursor SSA/Ps...
March 21, 2017: Cancer Prevention Research
https://www.readbyqxmd.com/read/28320200/clinical-and-biological-features-of-interval-colorectal-cancer
#6
Yu Mi Lee, Kyu Chan Huh
Interval colorectal cancer (I-CRC) is defined as a CRC diagnosed within 60 months after a negative colonoscopy, taking into account that 5 years is the "mean sojourn time." It is important to prevent the development of interval cancer. The development of interval colon cancer is associated with female sex, old age, family history of CRC, comorbidities, diverticulosis, and the skill of the endoscopist. During carcinogenesis, sessile serrated adenomas/polyps (SSA/Ps) share many genomic and colonic site characteristics with I-CRCs...
March 21, 2017: Clinical Endoscopy
https://www.readbyqxmd.com/read/28316766/colonic-laterally-spreading-tumor-diagnosed-as-an-early-cancer-and-treated-with-endoscopic-mucosal-resection-a-case-report-and-review-of-literature
#7
Mohamad Abdelaziz, Motaz Sayed
Laterally spreading tumors (LSTs) are generally defined as superficial lesions ≥10 mm in diameter that typically extend laterally rather than vertically along the colonic wall. Such lesions are now increasingly reported because of increased awareness and the introduction of chromo and magnifying colonoscopy. Although the clinicopathological characteristics and the efficacy of endoscopic management of LSTs have been defined in Japanese cohorts, reports from the Middle East are lacking where surgical resection is the mainstay of treatment...
January 2017: Middle East Journal of Digestive Diseases
https://www.readbyqxmd.com/read/28303455/duodenal-cancer-in-a-young-patient-with-peuts-jeghers-syndrome-harboring-an-entire-deletion-of-the-stk11-gene
#8
Satoshi Teramae, Koichi Okamoto, Kumiko Tanaka, Reika Matsumoto, Shinji Kitamura, Tetsuo Kimura, Masahiro Sogabe, Hiroshi Miyamoto, Naoki Muguruma, Yoshimi Bando, Mitsuo Shimada, Tetsuji Takayama
A 21-year-old woman with Peuts-Jeghers syndrome (PJS) was referred to our hospital for gastrointestinal surveillance. She had been diagnosed as having PJS from a young age based on her family history and the presence of mucocutaneous pigmentation on her lips and oral mucosa. Her mother and brother had PJS harboring an entire deletion of the STK11 gene. She had tetralogy of Fallot, atrial tachycardia, sick sinus syndrome, and mental retardation in her past history. Esophagogastroduodenoscopy identified a protruded lesion with a depressed area that occupied the lumen half-circumferentially in the duodenal second portion and also showed a 10-mm protruded lesion on the anterior wall of the lower gastric body...
March 16, 2017: Clinical Journal of Gastroenterology
https://www.readbyqxmd.com/read/28302537/mcm2-expression-in-serrated-polyps-demonstrates-aberrant-cellular-proliferation
#9
Danielle Fortuna, Bruce Boman, Raymond O'Neil, Juan Palazzo
In normal colonic epithelium, the proliferative zone is limited to the lower half of the colonic crypt. Evaluating the changes in the colonic epithelial proliferation can be useful in understanding pathophysiology of various diseases. Our aim was to investigate the proliferative compartment of serrated polyps (SPs) using MCM2, a protein involved in DNA replication, and assess for changes along the SP spectrum. Immunohistochemistry was performed on serrated polyps (16 microvesicular-type hyperplastic polyps (HP), 58 sessile serrated adenomas (SSA), seven SSAs with dysplasia) and six sections of normal colon using anti-MCM2 antibody...
March 13, 2017: Human Pathology
https://www.readbyqxmd.com/read/28300642/distribution-and-phylogeny-of-brachyspira-spp-in-human-intestinal-spirochetosis-revealed-by-fish-and-16s-rrna-gene-analysis
#10
Pablo Rojas, Annett Petrich, Julia Schulze, Alexandra Wiessner, Christoph Loddenkemper, Hans-Jörg Epple, William Sterlacci, Michael Vieth, Judith Kikhney, Annette Moter
During six years as National Reference Laboratory for Spirochetes we investigated 149 intestinal biopsies from 91 patients, which were histopathologically diagnosed with human intestinal spirochetosis (HIS), using fluorescence in situ hybridization (FISH) combined with 16S rRNA gene PCR and sequencing. Aim of this study was to complement histopathological findings with FISH and PCR for definite diagnosis and species identification of the causative pathogens. HIS is characterized by colonization of the colonic mucosa of the human distal intestinal tract by Brachyspira spp...
March 11, 2017: Anaerobe
https://www.readbyqxmd.com/read/28299354/an-international-survey-of-polypectomy-training-and-assessment
#11
K Patel, A Rajendran, O Faiz, M D Rutter, C Rutter, R Jover, I Koutroubakis, W Januszewicz, M Ferlitsch, E Dekker, D MacIntosh, S C Ng, T Kitiyakara, H Pohl, S Thomas-Gibson
Background and study aims Colonic polypectomy is acknowledged to be a technically challenging part of colonoscopy. Training in polypectomy is recognized to be often inconsistent. This study aimed to ascertain worldwide practice in polypectomy training. Patients and methods An electronic survey was distributed to endoscopic trainees and trainers in 19 countries asking about their experiences of receiving and delivering training. Participants were also asked about whether formal polypectomy training guidance existed in their country...
March 2017: Endoscopy International Open
https://www.readbyqxmd.com/read/28295697/diagnostic-capability-of-colon-capsule-endoscopy-for-advanced-colorectal-cancer-a-pilot-study
#12
Yumiko Ota, Atsuo Yamada, Yuka Kobayashi, Ryota Niikura, Takayuki Shimpoh, Akiko Narita, Shuntaro Yoshida, Nobumi Suzuki, Hirotsugu Watabe, Yoshihiro Hirata, Soichiro Ishihara, Eiji Sunami, Toshiaki Watanabe, Kazuhiko Koike
OBJECTIVES: Colon capsule endoscopy (CCE) is a safe and effective method for detecting lesions in the colon. However, the sensitivity of CCE in detecting advanced colorectal cancer (CRC) has not been sufficiently evaluated. Therefore, the aim of this study was to assess the sensitivity of CCE in detecting advanced CRC. METHODS: Patients previously diagnosed with advanced CRC by conventional colonoscopy underwent CCE. The primary outcome measure was the sensitivity of CCE in detecting advanced CRC per patient and per lesion...
March 10, 2017: Digestive Endoscopy: Official Journal of the Japan Gastroenterological Endoscopy Society
https://www.readbyqxmd.com/read/28295534/mucin-rich-variant-of-traditional-serrated-adenoma-mrtsa-a-distinct-morphological-variant
#13
Sangeetha N Kalimuthu, Stefano Serra, Sara Hafezi-Bakhtiari, Richard Colling, Lai Mun Wang, Runjan Chetty
Traditional serrated adenomas (TSAs) account for 5% of serrated polyps, have villiform architecture, eosinophilic cells with a brush border and indented, flat-topped luminal serrations. However, some are composed of mucin-filled goblet cells (GC): a mucin-rich variant (MrTSA). The aim of this study was to determine if this variant has unique features compared to classic TSA (cTSA). 156 TSAs were retrieved from 2010-2016. Patient demographics, site of polyps, and 16 microscopic variables, were evaluated. TSAs containing 50% or more GCs were classified as MrTSAs...
March 13, 2017: Histopathology
https://www.readbyqxmd.com/read/28295005/-the-expression-of-claudins-in-colonic-neoplasms
#14
N A Oleinikova, O A Kharlova, P G Mal'kov, N V Danilova
AIM: the evaluation of localization claudin-1, -3 and -4 types of cancer and colon polyps. MATERIAL AND METHODS: The study included 32 colon adenocarcinoma and 86 polyps. Antibody claudin-1; -3 and -4 were used as immunohistochemical markers in this study. RESULTS: 84/118, 64/118, 52/118 reaction with claudin-1, claudin-3 and claudin-4 in cancer and colon polyps had a membrane localization, respectively. In 33 (27.9%) cases was found paradoxical reaction claudin-1; in 50 (42...
2017: Arkhiv Patologii
https://www.readbyqxmd.com/read/28295004/-serrated-adenomas-of-the-colon-clinical-morphological-and-molecular-genetic-characteristics
#15
L M Mikhaleva, R A Komleva, A E Biryukov, N K Shakhpazyan
AIM: to investigate the clinical, morphological, and molecular genetic characteristics of serrated adenomas of the colon. MATERIAL AND METHODS: The study included 82 colon adenomas from 63 patients aged 29 to 81 years, who underwent colonoscopy with biopsy or polypectomy. The mean age of men was 63.3 years; that of women was 56.8 years. Comprehensive clinical, morphological, immunohistochemical, and molecular genetic examinations were made. RESULTS: The histological examination showed that sessile serrated adenomas (SSA) of the colon were most common (46...
2017: Arkhiv Patologii
https://www.readbyqxmd.com/read/28293641/functional-effects-of-prebiotic-fructans-in-colon-cancer-and-calcium-metabolism-in-animal-models
#16
Marisol Rivera-Huerta, Vania Lorena Lizárraga-Grimes, Ibrahim Guillermo Castro-Torres, Mabel Tinoco-Méndez, Lucía Macías-Rosales, Francisco Sánchez-Bartéz, Graciela Guadalupe Tapia-Pérez, Laura Romero-Romero, María Isabel Gracia-Mora
Inulin-type fructans are polymers of fructose molecules and are known for their capacity to enhance absorption of calcium and magnesium, to modulate gut microbiota and energy metabolism, and to improve glycemia. We evaluated and compared the effects of Chicory inulin "Synergy 1®" and inulin from Mexican agave "Metlin®" in two experimental models of colon cancer and bone calcium metabolism in mice and rats. Inulins inhibited the development of dextran sulfate sodium-induced colitis and colon cancer in mice; these fructans reduced the concentration of tumor necrosis factor alpha and prevented the formation of intestinal polyps, villous atrophy, and lymphoid hyperplasia...
2017: BioMed Research International
https://www.readbyqxmd.com/read/28289662/mucosa-associated-lymphoid-tissue-lymphoma-of-the-cecum-and-rectum-a-case-report
#17
Myung Jin Nam, Byung Chang Kim, Sung Chan Park, Chang Won Hong, Kyung Su Han, Dae Kyung Sohn, Weon Seo Park, Hee Jin Chang, Jae Hwan Oh
A colonic mucosa-associated lymphoid-tissue (MALT) lymphoma is relatively rare compared to lymphomas of the stomach or small intestine. We present a case of a MALT lymphoma in the cecum and rectum found during screening colonoscopy. A 54-year-old female, who had undergone right-breast-conserving surgery with axillary dissection due to an invasive ductal carcinoma and a left-breast excisional biopsy due to microcalcification following adjuvant chemoradiation therapy 3 years earlier, was found to have 3-mm-sized smooth elevated lesions in both the cecum and rectum...
February 2017: Annals of Coloproctology
https://www.readbyqxmd.com/read/28286563/antispasmodic-drugs-in-colonoscopy-a-review-of-their-pharmacology-safety-and-efficacy-in-improving-polyp-detection-and-related-outcomes
#18
REVIEW
Santosh Sanagapalli, Kriti Agnihotri, Rupert Leong, Crispin John Corte
Antispasmodic drugs are cheap, effective and generally safe. They may improve outcomes in colonoscopy, however their use has not been consistent or widespread. This manuscript reviews the three most commonly used antispasmodics in colonoscopy, namely, hyoscine butylbromide (and related ammonium compounds), glucagon and peppermint oil. The pharmacology, action and safety of the agents, as well as the evidence for them improving colonoscopic outcomes will be discussed. In addition to polyp detection, other colonoscopic outcome endpoints of interest include cecal and ileal intubation, and patient comfort...
January 2017: Therapeutic Advances in Gastroenterology
https://www.readbyqxmd.com/read/28281908/increasing-navigation-speed-at-endoluminal-ct-colonography-reduces-colonic-visualization-and-polyp-identification
#19
Andrew A Plumb, Peter Phillips, Graeme Spence, Susan Mallett, Stuart A Taylor, Steve Halligan, Thomas Fanshawe
Purpose To investigate the effect of increasing navigation speed on the visual search and decision making during polyp identification for computed tomography (CT) colonography Materials and Methods Institutional review board permission was obtained to use deidentified CT colonography data for this prospective reader study. After obtaining informed consent from the readers, 12 CT colonography fly-through examinations that depicted eight polyps were presented at four different fixed navigation speeds to 23 radiologists...
March 10, 2017: Radiology
https://www.readbyqxmd.com/read/28280339/evaluation-of-a-novel-fluorescent-nanobeacon-for-targeted-imaging-of-thomsen-friedenreich-associated-colorectal-cancer
#20
Hiroshi Nakase, Shinji Sakuma, Takumi Fukuchi, Takuya Yoshino, Kohta Mohri, Kohei Miyata, Hironori Kumagai, Ken-Ichiro Hiwatari, Kazufumi Tsubaki, Tetsuya Ikejima, Etsuo Tobita, Meiying Zhu, Kevin J Wilson, Kay Washington, John C Gore, Wellington Pham
The Thomsen-Friedenreich (TF) antigen represents a prognostic biomarker of colorectal carcinoma. Here, using a nanobeacon, the surface of which was fabricated with peanut agglutinin as TF-binding molecules, we demonstrate that the nanobeacon is able to detect TF antigen in frozen and freshly biopsied polyps using fluorescence microscopy. Our results provide important clues about how to detect aberrant colonic tissues in the most timely fashion. Given the versatile application method for this topical nanobeacon, the protocol used in this work is amenable to clinical colonoscopy...
2017: International Journal of Nanomedicine
keyword
keyword
55133
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"