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https://www.readbyqxmd.com/read/27936385/interrater-reliability-in-pediatric-urodynamic-tracings-a-pilot-study
#1
Anne G Dudley, Daniel P Casella, Chelsea J Lauderdale, Shilin Zhao, Heidi Chen, Stacy T Tanaka, John C Thomas, John C Pope, Mark C Adams, John W Brock, Chevis N Shannon, Douglass B Clayton
PURPOSE: Urodynamic studies are crucial to neuropathic bladder management and they often determine surgical intervention. However, current evidence indicates that interpretations show poor agreement across physicians. We sought to determine the interrater reliability of urodynamic interpretation in our practice. We hypothesized that there would be strong correlation among pediatric urologists of similar training in a single academic practice. MATERIALS AND METHODS: We retrospectively identified patients with neuropathic bladder who underwent urodynamics at our institution between 2014 and 2015...
December 6, 2016: Journal of Urology
https://www.readbyqxmd.com/read/27936368/utility-of-brief-versions-of-the-alcohol-use-disorders-identification-test-audit-to-identify-excessive-drinking-among-patients-in-hiv-care-in-south-africa
#2
Neo K Morojele, Sebenzile Nkosi, Connie T Kekwaletswe, Paul A Shuper, Samuel O Manda, Bronwyn Myers, Charles D H Parry
OBJECTIVE: In sub-Saharan Africa, large proportions of patients who are on antiretroviral therapy (ART) engage in excessive alcohol use, which may lead to adverse health consequences and may go undetected. Consequently, health care workers need brief screening tools to be able to routinely identify and manage excessive alcohol use among their patients. Various brief versions of the valid and reliable 10-item Alcohol Use Disorders Identification Test (AUDIT) (i.e., the AUDIT-C, AUDIT-3, AUDIT-QF, AUDIT-PC, AUDIT-4, and m-FAST) may potentially replace the full AUDIT in busy HIV care settings...
January 2017: Journal of Studies on Alcohol and Drugs
https://www.readbyqxmd.com/read/27936243/can-wound-exudate-from-venous-leg-ulcers-measure-wound-pain-status-a-pilot-study
#3
Taichi Goto, Nao Tamai, Gojiro Nakagami, Aya Kitamura, Ayumi Naito, Masayuki Hirokawa, Chisako Shimokawa, Kazuo Takahashi, Junichi Umemoto, Hiromi Sanada
We investigated the associations between the self-evaluated pain status and two pain biomarker candidates, nerve growth factor and S100A8/A9, in exudate from venous leg ulcer to finally develop an objective pain evaluation method. Patients with venous leg ulcer participated in this cross-sectional observational study conducted between April and October 2014 at two medical facilities. During routine wound care, each participant self-evaluated their pain status at each examination using the 10-point numerical rating scale (present pain intensity) and the short-form McGill Pain Questionnaire 2 (continuous pain, intermittent pain, neuropathic pain, affective descriptors, and total score)...
2016: PloS One
https://www.readbyqxmd.com/read/27936086/geographical-heterogeneity-of-multiple-sclerosis-prevalence-in-france
#4
Diane Pivot, Marc Debouverie, Michel Grzebyk, David Brassat, Michel Clanet, Pierre Clavelou, Christian Confavreux, Gilles Edan, Emmanuelle Leray, Thibault Moreau, Sandra Vukusic, Guy Hédelin, Francis Guillemin
INTRODUCTION: Geographical variation in the prevalence of multiple sclerosis (MS) is controversial. Heterogeneity is important to acknowledge to adapt the provision of care within the healthcare system. We aimed to investigate differences in prevalence of MS in departments in the French territory. METHODS: We estimated MS prevalence on October 31, 2004 in 21 administrative departments in France (22% of the metropolitan departments) by using multiple data sources: the main French health insurance systems, neurologist networks devoted to MS and the Technical Information Agency of Hospitalization...
2016: PloS One
https://www.readbyqxmd.com/read/27935988/effects-of-a-community-based-healthy-lifestyle-intervention-program-co-help-among-adults-with-prediabetes-in-a-developing-country-a-quasi-experimental-study
#5
Norliza Ibrahim, Foong Ming Moy, Intan Attikah Nur Awalludin, Zainudin Mohd Ali, Ikram Shah Ismail
BACKGROUND: The prevalence of type 2 diabetes among Malaysian adults has increased by more than two folds over the past two decades. Strategies to collaborate with the existing community partners may become a promising channel for wide-scale dissemination of diabetes prevention in the country. The objectives of this study were to determine the effects of community-based lifestyle interventions delivered to adults with prediabetes and their health-related quality of life as compared to the usual care group...
2016: PloS One
https://www.readbyqxmd.com/read/27935809/assessing-and-measuring-cognitive-function-in-major-depressive-disorder
#6
Renee-Marie Ragguett, Danielle S Cha, Ron Kakar, Joshua D Rosenblat, Yena Lee, Roger S McIntyre
Cognitive dysfunction is a major component of major depressive disorder (MDD). No 'gold-standard' tool exists for the assessment of cognitive dysfunction for adults with MDD. The use of measurement-based care to improve treatment outcomes invites the need for a systematic screening, evaluation and measurement tool. The aim herein was to provide a succinct summary of literature documenting clinical implication of cognitive dysfunction in MDD, and a review of available screening, diagnostic and measurement tools for cognitive dysfunction in MDD is provided...
November 2016: Evidence-based Mental Health
https://www.readbyqxmd.com/read/27935774/communication-in-the-operating-room-setting
#7
Lisa Osborne-Smith, R Kyle Hodgen
Ideal and effective communication consists of a clear, audible, and focused message from a transmitter that is delivered to an attentive, undistracted receiver, and consists of both verbal and nonverbal types. Communication in the health care setting is highly complex and dynamic, involving multiple settings, participants, and unique challenges. Effective communication in the perioperative environment is a requirement for safe patient care delivery and an important element of teamwork. A message must be accurately delivered in a uniquely high-risk and time-sensitive location, beset with numerous distractions, barriers, and challenges...
January 2017: Annual Review of Nursing Research
https://www.readbyqxmd.com/read/27935767/effect-of-physical-activity-and-or-healthy-eating-on-gdm-risk-the-dali-lifestyle-study
#8
David Simmons, Roland Devlieger, André van Assche, Goele Jans, Sander Galjaard, Rosa Corcoy, Juan M Adelantado, Fidelma Dunne, Gernot Desoye, Jürgen Harreiter, Alexandra Kautzky-Willer, Peter Damm, Elisabeth R Mathiesen, Dorte M Jensen, Liselotte Andersen, Annunziata Lapolla, Maria G Dalfrà, Alessandra Bertolotto, Ewa Wender-Ozegowska, Agnieszka Zawiejska, David Hill, Frank J Snoek, Judith Gm Jelsma, Mireille Nm van Poppel
CONTEXT: Lifestyle approaches for preventing gestational diabetes mellitus (GDM) have produced mixed results. OBJECTIVE: The aim of this study was to compare the effectiveness of three lifestyle interventions (Healthy eating (HE), Physical activity (PA) and both HE and PA (HE+PA)) with usual care (UC) in reducing GDM risk. DESIGN: Multicentre Randomised Controlled Trial 2012-2014: The Dali Lifestyle Study Setting: Antenatal clinics across 11 centres in 9 European countries Patients: Consecutive pregnant women <20 weeks gestation with a BMI≥29 kg/m(2) and without GDM by IADPSG criteria (n=436)...
December 9, 2016: Journal of Clinical Endocrinology and Metabolism
https://www.readbyqxmd.com/read/27935657/profile-and-reintegration-experience-of-ebola-survivors-in-guinea-a-cross-sectional-study
#9
Alexandre Delamou, Bienvenu Salim Camara, Jean Pe Kolie, Achille Diona Guemou, Nyankoye Yves Haba, Shannon Marquez, Beavogui Abdoul Habib, Therese Delvaux, Johan van Griensven
OBJECTIVE: To describe the experience of Guinean Ebola Virus Disease (EVD) survivors in Guinea, up to ten months after discharge from the Ebola treatment unit. METHODS: Cross-sectional study using a standardized semi-structured questionnaire among survivors from Conakry and Coyah districts in 2015 in Guinea. We used proportions, mean (Standard Deviation) and median (Interquartile range) to summarize the variables. The McNemar Chi square test was used to compare proportions...
December 9, 2016: Tropical Medicine & International Health: TM & IH
https://www.readbyqxmd.com/read/27935627/clinical-evaluation-of-statstrip-%C3%A2-lactate-for-use-in-fetal-scalp-blood-sampling
#10
Ayesha Heinis, Jeroen van Dillen, Janine Oosting, Sarah Rhöse, Frank Vandenbussche, Joris Van Drongelen
INTRODUCTION: Point-of-care testing of fetal scalp blood lactate is used as an alternative for pH analysis in fetal scalp blood sampling (FBS) during labor. Lactate measurements are not standardized and values vary with each device used. The aim of this study was to evaluate StatStrip Lactate (SSL) in the clinical setting in comparison to lactate (RLL) and pH (RLpH) by RapidLab. MATERIALS AND METHODS: We obtained 323 FBS samples from 139 women. Parallel sampling of SSL and RLL/RLpH was performed in 247 samples...
December 9, 2016: Acta Obstetricia et Gynecologica Scandinavica
https://www.readbyqxmd.com/read/27935536/evaluation-of-a-12-month-pilot-of-long-term-and-temporary-assisted-peritoneal-dialysis
#11
Micheli U Bevilacqua, Linda Turnbull, Sushila Saunders, Lee Er, Helen Chiu, Penny Hill, Rajinder S Singh, Adeera Levin, Michael A Copland, Abeed Jamal, Catherine Brumby, Orla Dunne, Paul A Taylor
♦ Background: Peritoneal dialysis (PD) is challenging for patients with functional limitations, and assisted PD can support these patients, but previous reports of assisted PD have not examined the role of temporary assisted PD and had difficulty identifying adequate comparator cohorts. ♦ Methods: Peritoneal Dialysis Assist (PDA), a 12-month pilot of long-term and temporary assisted PD was completed in multiple PD centers in British Columbia, Canada. Continuous cycler PD (CCPD) patients were identified for PDA by standardized criteria, and service could be long-term or temporary/respite...
December 1, 2016: Peritoneal Dialysis International: Journal of the International Society for Peritoneal Dialysis
https://www.readbyqxmd.com/read/27935523/telehealth-methods-to-deliver-dietary-interventions-in-adults-with-chronic-disease-a-systematic-review-and-meta-analysis
#12
Jaimon T Kelly, Dianne P Reidlinger, Tammy C Hoffmann, Katrina L Campbell
BACKGROUND: The long-term management of chronic disease requires the adoption of complex dietary recommendations, which can be facilitated by regular coaching to support behavioral changes. Telehealth interventions can overcome patient-centered barriers to accessing face-to-face programs and provide feasible delivery methods, accessible regardless of geographic location. OBJECTIVE: This systematic review assessed the effectiveness of telehealth dietary interventions at facilitating dietary change in chronic disease...
December 2016: American Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/27935091/fabrication-of-complete-dentures-in-three-visits-using-existing-prosthesis-a-simplified-technique-for-geriatric-patients
#13
Rahul S Kulkarni, Ravindra S Pawar
Complete edentulism often limits patients' ability to masticate and perform other oral functions, resulting in a reduction of oral-health-related quality of life. Although the two-implant mandibular overdenture may be considered as a minimum standard of treatment of complete edentulism, patients often prefer conventional complete dentures due to cost and surgical procedures related to implant supported dentures. Many complete denture patients may have limited access to dental care due to socioeconomic or health issues, hence there is a need in simplification of complete denture fabrication...
December 9, 2016: Special Care in Dentistry
https://www.readbyqxmd.com/read/27935024/risk-factors-for-dental-caries-among-children-with-cerebral-palsy-in-a-low-resource-setting
#14
Rahena Akhter, Nur Mohammad Monsur Hassan, Elizabeth F Martin, Mohammad Muhit, Raziur Rahman, Hayley Smithers-Sheedy, Cheryl Jones, Nadia Badawi, Gulam Khandaker
AIM: To describe the oral health status and investigate factors affecting dental caries experience among children with cerebral palsy (CP) in rural Bangladesh. METHOD: A cross-sectional study was conducted among children with CP who are part of the Bangladesh Cerebral Palsy Register (BCPR) study. Caries experience was measured by identifying decayed, missing, and filled teeth for deciduous and permanent teeth (dmft/DMFT). Clinical periodontal index, body mass index, oral hygiene behaviour, masticatory ability, and dietary habits were recorded...
December 9, 2016: Developmental Medicine and Child Neurology
https://www.readbyqxmd.com/read/27934835/six-year-susceptibility-trends-and-effect-of-revised-clinical-laboratory-standards-institute-breakpoints-on-ciprofloxacin-susceptibility-reporting-in-typhoidal-salmonellae-in-a-tertiary-care-paediatric-hospital-in-northern-india
#15
R Saksena, C Nayyar, V Manchanda
The antimicrobial trends over 6 years were studied, and the effect of revised Clinical Laboratory Standards Institute (CLSI) breakpoints (2012) for ciprofloxacin susceptibility reporting in typhoidal Salmonellae was determined. A total of 874 (95.4%) isolates were nalidixic acid-resistant (NAR). Using the CLSI 2011 guidelines (M100-S21), 585 (66.9%) isolates were ciprofloxacin susceptible. The susceptibility reduced to 11 (1.25%) isolates when interpreted using 2012 guidelines (M100-S22). Among the forty nalidixic acid susceptible (NAS) Salmonellae, susceptibility to ciprofloxacin decreased from 37 isolates (M100-S21) to 12 isolates (M100-S22)...
October 2016: Indian Journal of Medical Microbiology
https://www.readbyqxmd.com/read/27934819/trend-of-human-brucellosis-over-a-decade-at-tertiary-care-centre-in-north-karnataka
#16
D P Patil, G S Ajantha, C Shubhada, P A Jain, A Kalabhavi, P C Shetty, M Hosamani, S Appannanavar, R D Kulkarni
BACKGROUND: Brucellosis is an important zoonotic disease. India having a major agrarian population is expected to have a higher prevalence. However, due to lack of laboratory facility or awareness among clinicians, the disease is largely underreported. The aim of this study was to know the prevalence and trend of human brucellosis over a decade, in patients attending a teaching hospital in North Karnataka, and to understand their geographical distribution. MATERIALS AND METHODS: The study was conducted from January 2006 to December 2015 at a tertiary care teaching hospital in North Karnataka...
October 2016: Indian Journal of Medical Microbiology
https://www.readbyqxmd.com/read/27933783/a-comprehensive-computational-analysis-for-the-binding-modes-of-hepatitis-c-virus-ns5a-inhibitors-the-question-of-symmetry
#17
Marawan Ahmed, Abhishek Pal, Michael Houghton, Khaled Barakat
Direct-acting antivirals (DAAs) form the current standard of care (SOC) against hepatitis C virus (HCV). These drugs selectively target the viral proteins, offering a unique mechanism to avoid toxicity, to increase their efficacy, and to evolve from decades of interferon- and ribavirin-based therapy. Among the promising HCV targets for DAAs is the NS5A protein, and daclatasvir (DCV) forms a first-in-class compound that selectively targets this protein. Despite the exceptional potency of DCV (∼picomolar IC50) and although several DCV derivatives have been approved for human use or are close to approval, the exact mode of action of these drugs is still incomplete...
November 11, 2016: ACS Infectious Diseases
https://www.readbyqxmd.com/read/27933698/sofosbuvir-plus-ribavirin-in-treatment-na%C3%A3-ve-patients-with-chronic-hepatitis-c-virus-genotype-1-or-3-infection-in-india
#18
S R Shah, A Chowdhury, R Mehta, D Kapoor, A Duseja, A Koshy, A Shukla, A Sood, K Madan, R Sud, S Nijhawan, R Pawan, M Prasad, K Kersey, D Jiang, E Svarovskaia, B Doehle, B Kanwar, M Subramanian, S K Acharya, S Sarin
Until 2014, pegylated interferon plus ribavirin was the recommended standard of care for the treatment of chronic hepatitis C virus (HCV) infection in India. This open-label phase 3b study, conducted across 14 sites in India between 31 March 2014 and 30 November 2015, evaluated the efficacy and safety of sofosbuvir plus ribavirin therapy among treatment-naïve patients with chronic genotype 1 or 3 HCV infection. A total of 117 patients with genotype 1 or 3 HCV infection were randomized 1:1 to receive sofosbuvir 400 mg and weight-based ribavirin (1000 or 1200 mg) daily for 16 or 24 weeks...
December 9, 2016: Journal of Viral Hepatitis
https://www.readbyqxmd.com/read/27933667/a-mobile-web-based-system-can-improve-positive-airway-pressure-adherence
#19
Jordanna M Hostler, Karen L Sheikh, Teotimo F Andrada, Andrei Khramtsov, Paul R Holley, Aaron B Holley
SleepMapper is a mobile, web-based system that allows patients to self-monitor their positive airway pressure therapy, and provides feedback and education in real time. In addition to the usual, comprehensive support provided at our clinic, we gave the SleepMapper to 30 patients initiating positive airway pressure. They were compared with patients initiating positive airway pressure at our clinic without SleepMapper (controls) to determine whether SleepMapper affected adherence. A total of 61 patients had polysomnographic and adherence data analysed, 30 were given SleepMapper and 31 received our standard of care...
December 8, 2016: Journal of Sleep Research
https://www.readbyqxmd.com/read/27933580/headache-service-quality-evaluation-of-quality-indicators-in-14-specialist-care-centres
#20
Sara Schramm, Derya Uluduz, Raquel Gil Gouveia, Rigmor Jensen, Aksel Siva, Ugur Uygunoglu, Giorgadze Gvantsa, Maka Mania, Mark Braschinsky, Elena Filatova, Nina Latysheva, Vera Osipova, Kirill Skorobogatykh, Julia Azimova, Andreas Straube, Ozan Emre Eren, Paolo Martelletti, Valerio De Angelis, Andrea Negro, Mattias Linde, Knut Hagen, Aleksandra Radojicic, Jasna Zidverc-Trajkovic, Ana Podgorac, Koen Paemeleire, Annelien De Pue, Christian Lampl, Timothy J Steiner, Zaza Katsarava
BACKGROUND: The study was a collaboration between Lifting The Burden (LTB) and the European Headache Federation (EHF). Its aim was to evaluate the implementation of quality indicators for headache care Europe-wide in specialist headache centres (level-3 according to the EHF/LTB standard). METHODS: Employing previously-developed instruments in 14 such centres, we made enquiries, in each, of health-care providers (doctors, nurses, psychologists, physiotherapists) and 50 patients, and analysed the medical records of 50 other patients...
December 2016: Journal of Headache and Pain
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