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https://www.readbyqxmd.com/read/27909551/post-endoscopic-retrograde-cholangiopancreatography-pancreatitis-risk-factors-and-predictors-of-severity
#1
Ayman El Nakeeb, Ehab El Hanafy, Tarek Salah, Ehab Atef, Hosam Hamed, Ahmad M Sultan, Emad Hamdy, Mohamed Said, Ahmed A El Geidie, Tharwat Kandil, Mohamed El Shobari, Gamal El Ebidy
AIM: To detect risk factors for post-endoscopic retrograde cholangiopancreatography (ERCP) pancreatitis (PEP) and investigate the predictors of its severity. METHODS: This is a prospective cohort study of all patients who underwent ERCP. Pre-ERCP data, intraoperative data, and post-ERCP data were collected. RESULTS: The study population consisted of 996 patients. Their mean age at presentation was 58.42 (± 14.72) years, and there were 454 male and 442 female patients...
November 16, 2016: World Journal of Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/27904545/treatment-of-recurrent-prosthetic-mitral-valve-thrombosis-with-reteplase-a-report-of-four-cases
#2
Neda Behzadnia, Babak Sharif Kashani, Arda Kiani, Atefe Abedini, Seyed Reza Seyedi, Hossein Zargham Ahmadi, Farah Naghash Zadeh, Atefeh Fakharian
Thrombosis is a life threatening complications of prosthetic mitral valves and is associated with high morbidity and mortality. Even in presence of systemic anticoagulation prosthetic valve thrombosis has an incidence of 0.5% to 8%. Recurrent prosthetic valve thrombosis and the resulting thrombotic occlusion require re-establishment of blood flow across the valve. While surgical repair is considered the classic first line treatment option for prosthetic valve thrombosis, intravenous thrombolysis has emerged as an acceptable alternative for the first episode of prosthetic valve thrombosis...
2016: Tanaffos
https://www.readbyqxmd.com/read/27890577/transcription-factors-regulating-uspa-genes-in-catharanthus%C3%A2-roseus
#3
Ahmed Bahieldin, Ahmed Atef, Ahmed M Shokry, Saleh Al-Karim, Sanaa G Al Attas, Nour O Gadallah, Sherif Edris, Magdy A Al-Kordy, Sabah M Hassan, Salah Abo-Aba, Fotouh M El-Domyati
RNA-Seq of the Catharanthus roseus SRA database was done in order to detect putative universal stress proteins (USPs) and their possible controlling factors. Previous analysis indicated the existence and characterization of uspA-like genes. In silico analysis of RNA-Seq database in several plant tissues revealed the possible functions and regulations of some uspA-like transcripts whose transcription factors (TFs) that might drive their expression were detected. BLAST indicated the existence of TF superfamilies erf (ethylene-responsive TF), bHLH (basic helix-loop-helix) and WRKY that might regulate several uspA-like genes...
November 24, 2016: Comptes Rendus Biologies
https://www.readbyqxmd.com/read/27887767/vascular-endothelial-growth-factor-g1612a-rs10434-gene-polymorphism-and-neuropsychiatric-manifestations-in-systemic-lupus-erythematosus-patients
#4
Sherif Taha, Sherif Mohammed Gamal, Mohamed Nabil, Nahla Naeem, Dalia Labib, Ibrahim Siam, Tamer Atef Gheita
AIM: To investigate the relation between vascular endothelial growth factor (VEGF) gene polymorphism in systemic lupus erythematosus (SLE) patients and lupus related neuropsychiatric manifestations. PATIENTS AND METHODS: Sixty adult SLE patients recruited from the Rheumatology and Neurology departments of Cairo University hospitals were classified into two groups; Group A: 30 patients with neuropsychiatric manifestations (NPSLE) and Group B: 30 patients without...
October 28, 2016: Revista Brasileira de Reumatologia
https://www.readbyqxmd.com/read/27862796/proton-gated-photoisomerization-of-amino-substituted-dibenzofulvene-rotors
#5
Udaya Jayasundara, HyunJong Kim, Krishna Sahteli, Joseph I Cline, Thomas W Bell
Derivatives of 9-(2,2,2-triphenylethylidene)-fluorene (TEF) undergo E/Z photoisomerization and are candidates for light-powered molecular actuators and switches. The 2-substituted derivatives bearing an amino group (ATEF) or a dimethylamino group (DTEF) are weakly photoactive in the absence of acids, but protonation increases photoisomerization quantum yields by factors of 30-60. Such compounds may be useful for incorporation into pH-switchable photoactive devices.
November 14, 2016: Chemphyschem: a European Journal of Chemical Physics and Physical Chemistry
https://www.readbyqxmd.com/read/27854148/first-detection-of-ges-5-carbapenemase-producing-acinetobacter-baumannii-isolate
#6
Mohamed H Al-Agamy, Katy Jeannot, Taghrid S El-Mahdy, Atef M Shibl, Wael Kattan, Patrick Plésiat, Patrice Courvalin
This study was conducted to investigate the molecular epidemiology of resistance in Acinetobacter baumannii isolates collected at a hospital in Riyadh, Saudi Arabia, from January through December 2010. Twenty-seven A. baumannii were highly resistant (MIC90 > 256 μg/ml) to ceftazidime, cefepime, and aztreonam. Imipenem resistance was seen in 24 isolates, of which 18 had an minimum inhibitory concentration (MIC) >32 μg/mL. Ciprofloxacin, gentamicin, and amikacin resistance was found in 93%, 52%, and 37% of all the isolates, respectively...
November 17, 2016: Microbial Drug Resistance: MDR: Mechanisms, Epidemiology, and Disease
https://www.readbyqxmd.com/read/27853964/brain-pathway-differences-between-parkinson-s-disease-patients-with-and-without-rem-sleep-behavior-disorder
#7
Mina Ansari, Farzaneh Rahmani, Mahsa Dolatshahi, Atefe Pooyan, Mohammad Hadi Aarabi
PURPOSE: REM (rapid eye movement) sleep behavior disorder (RBD) is characterized by increased muscle tone and violent limb movements and is a usual symptom of the early stages of Parkinson's disease (PD). PD patients with RBD represent faster motor and cognitive dysfunction progression. However, there are limited studies on possible structural brain changes underpinning this disorder. METHODS: Diffusion magnetic resonance imaging (DMRI) was used to assess whether microstructural abnormalities in the brain of 23 RBD positive PD are detectable compared to 31 RBD negative PD...
November 16, 2016: Sleep & Breathing, Schlaf & Atmung
https://www.readbyqxmd.com/read/27842501/analysis-of-transcriptional-response-to-heat-stress-in-rhazya-stricta
#8
Abdullah Y Obaid, Jamal S M Sabir, Ahmed Atef, Xuan Liu, Sherif Edris, Fotouh M El-Domyati, Mohammed Z Mutwakil, Nour O Gadalla, Nahid H Hajrah, Magdy A Al-Kordy, Neil Hall, Ahmed Bahieldin, Robert K Jansen
BACKGROUND: Climate change is predicted to be a serious threat to agriculture due to the need for crops to be able to tolerate increased heat stress. Desert plants have already adapted to high levels of heat stress so they make excellent systems for identifying genes involved in thermotolerance. Rhazya stricta is an evergreen shrub that is native to extremely hot regions across Western and South Asia, making it an excellent system for examining plant responses to heat stress. Transcriptomes of apical and mature leaves of R...
November 14, 2016: BMC Plant Biology
https://www.readbyqxmd.com/read/27833124/erlotinib-conjugated-iron-oxide-nanoparticles-as-a-smart-cancer-targeted-theranostic-probe-for-mri
#9
Ahmed Atef Ahmed Ali, Fei-Ting Hsu, Chia-Ling Hsieh, Chia-Yang Shiau, Chiao-Hsi Chiang, Zung-Hang Wei, Cheng-Yu Chen, Hsu-Shan Huang
We designed and synthesized novel theranostic nanoparticles that showed the considerable potential for clinical use in targeted therapy, and non-invasive real-time monitoring of tumors by MRI. Our nanoparticles were ultra-small with superparamagnetic iron oxide cores, conjugated to erlotinib (FeDC-E NPs). Such smart targeted nanoparticles have the preference to release the drug intracellularly rather than into the bloodstream, and specifically recognize and kill cancer cells that overexpress EGFR while being non-toxic to EGFR-negative cells...
November 11, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27799529/mapping-intracellular-mechanics-on-micropatterned-substrates
#10
Kalpana Mandal, Atef Asnacios, Bruno Goud, Jean-Baptiste Manneville
The mechanical properties of cells impact on their architecture, their migration, intracellular trafficking, and many other cellular functions and have been shown to be modified during cancer progression. We have developed an approach to map the intracellular mechanical properties of living cells by combining micropatterning and optical tweezers-based active microrheology. We optically trap micrometer-sized beads internalized in cells plated on crossbow-shaped adhesive micropatterns and track their displacement following a step displacement of the cell...
October 31, 2016: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/27768350/multiple-rabi-splittings-under-ultrastrong-vibrational-coupling
#11
Jino George, Thibault Chervy, Atef Shalabney, Eloïse Devaux, Hidefumi Hiura, Cyriaque Genet, Thomas W Ebbesen
From the high vibrational dipolar strength offered by molecular liquids, we demonstrate that a molecular vibration can be ultrastrongly coupled to multiple IR cavity modes, with Rabi splittings reaching 24% of the vibration frequencies. As a proof of the ultrastrong coupling regime, our experimental data unambiguously reveal the contributions to the polaritonic dynamics coming from the antiresonant terms in the interaction energy and from the dipolar self-energy of the molecular vibrations themselves. In particular, we measure the opening of a genuine vibrational polaritonic band gap of ca...
October 7, 2016: Physical Review Letters
https://www.readbyqxmd.com/read/27761074/catha-edulis-khat-induces-apoptosis-in-madin-darby-bovine-kidney-cell-line
#12
Hussein M Ageely, Ahmed E Agag, Syam Mohan, Atef Shehata
BACKGROUND: Khat (Catha edulis) is a controversial plant having a euphoretic effect, at the same time part of culture in many countries such as Africa and Arabian Peninsula. The presence of amphetamine-like substance, cathinone and cathine make this plant banned in many countries. Many neurological and other system related studies have been carried out in this plant, but the lack of toxicity studies are there especially the mechanism. OBJECTIVE: In this study, Madin-Darby Bovine Kidney cell line was used as an in vitro model to study the cell death mechanism...
July 2016: Pharmacognosy Magazine
https://www.readbyqxmd.com/read/27743165/increased-proliferative-activity-accompanies-the-local-inflammatory-response-of-gastric-mucosa-after-intragastric-balloon-insertion
#13
Ehab Atef, Khaled Refaat Zalata, Hoda Atef, Ahmed A M Abdel-Hamid
BACKGROUND AND AIM: The use of BioEnterics intragastric balloon (BIB) is progressively increasing, owing to the fact that morbid obesity becomes a global epidemic together with risks of bariatric surgery. Yet, the possible local BIB effect on gastric mucosa is not clearly elucidated. The aim of the current study was to assess the histological changes occurring in the gastric mucosa post-BIB insertion. METHODS: Gastric mucosa biopsy was obtained from 87 cases of morbid obesity both pre-BIB and 6 months post-BIB insertion to compare the local changes by histological and immunohistochemical analysis...
October 14, 2016: Digestive Diseases and Sciences
https://www.readbyqxmd.com/read/27737721/children-in-the-syrian-civil-war-the-familial-educational-and-public-health-impact-of-ongoing-violence
#14
Abdallah Mohamed Elsafti, Gerlant van Berlaer, Mohammad Al Safadi, Michel Debacker, Ronald Buyl, Atef Redwan, Ives Hubloue
OBJECTIVE: The Syrian civil war since 2011 has led to one of the most complex humanitarian emergencies in history. The objective of this study was to document the impact of the conflict on the familial, educational, and public health state of Syrian children. METHODS: A cross-sectional observational study was conducted in May 2015. Health care workers visited families with a prospectively designed data sheet in 4 Northern Syrian governorates. RESULTS: The 1001 children included in this study originated from Aleppo (41%), Idleb (36%), Hamah (15%), and Lattakia (8%)...
October 14, 2016: Disaster Medicine and Public Health Preparedness
https://www.readbyqxmd.com/read/27721503/mhda-functionalized-multiwall-carbon-nanotubes-for-detecting-non-aromatic-vocs
#15
Atef Thamri, Hamdi Baccar, Claudia Struzzi, Carla Bittencourt, Adnane Abdelghani, Eduard Llobet
The chemical modification of multiwalled carbon nanotubes (MWCNTs) with a long chain mercapto acid is reported as a way to improve sensitivity and response time of gas sensors for detecting alcohols, acetone and toxic gases such as DMMP. We have developed sensors employing MWCNTs decorated with gold nanoparticles and modified with a 16-mercaptohexadecanoic acid (MHDA) monolayer. Morphological and compositional analysis by Transmission Electron Microscopy (TEM), Fourier Transform Infra-red Spectroscopy (FTIR) and X-ray photoelectron spectroscopy were performed to characterize the gold nanoparticles and to check the bonding of the thiol monolayer...
October 10, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27716054/ethylene-responsive-transcription-factor-erf109-retards-pcd-and-improves-salt-tolerance-in-plant
#16
Ahmed Bahieldin, Ahmed Atef, Sherif Edris, Nour O Gadalla, Hani M Ali, Sabah M Hassan, Magdy A Al-Kordy, Ahmed M Ramadan, Rania M Makki, Abdulrahman S M Al-Hajar, Fotouh M El-Domyati
BACKGROUND: The ultimate goal of this work was to detect the role of transcription factors (TFs) concordantly expressed with genes related to programmed cell death (PCD) during PCD and salt stress. This work was based on the hypothesis that TFs and their driven genes likely co-express under different stimuli. The conserved superfamily ethylene responsive factor (AP2/ERF) draw attention of the present study as it participates in the response to biotic and abiotic stimuli as well as to program cell death (PCD)...
October 6, 2016: BMC Plant Biology
https://www.readbyqxmd.com/read/27704520/the-emergent-use-of-cardiopulmonary-bypass-and-extracorporeal-membrane-oxygenator-in-a-child-with-sickle-cell-disease
#17
Wassim Ben Ameur, Sonia Ouerghi, Amira Dridi, Mouna Bousnina, Atef Ben Youssef, Tarek Kilani, Tahar Mestiri
The use of Cardiopulmonary bypass (CPB) and extracorporeal membrane oxygenator (ECMO) in patients suffering from Sickle cell disease (SCD) needs specific precautions. Whereas, no consensual protocols have been established to clarify therapeutic management. CASE REPORT A 7-year-old boy was admitted to the hospital for surgery of advanced endocarditis.  Major dyspnea, hemodynamic distress and fever were noted on physical examination. Biological tests exploring anaemia revealed Haemoglobin (Hb) S levels of 39...
April 2016: La Tunisie Médicale
https://www.readbyqxmd.com/read/27689759/quantum-strong-coupling-with-protein-vibrational-modes
#18
Robrecht M A Vergauwe, Jino George, Thibault Chervy, James A Hutchison, Atef Shalabney, Vladimir Y Torbeev, Thomas W Ebbesen
In quantum electrodynamics, matter can be hybridized to confined optical fields by a process known as light-matter strong coupling. This gives rise to new hybrid light-matter states and energy levels in the coupled material, leading to modified physical and chemical properties. Here, we report for the first time the strong coupling of vibrational modes of proteins with the vacuum field of a Fabry-Perot mid-infrared cavity. For two model systems, poly(l-glutamic acid) and bovine serum albumin, strong coupling is confirmed by the anticrossing in the dispersion curve, the square root dependence on the concentration, and a vacuum Rabi splitting that is larger than the cavity and vibration line widths...
October 7, 2016: Journal of Physical Chemistry Letters
https://www.readbyqxmd.com/read/27665196/determinants-of-women-s-sexual-dissatisfaction-assessing-a-cognitive-emotional-model
#19
Atefe Abdolmanafi, Richard Glynn Owens, Sam Winter, Reza Ghorban Jahromi, Maria Manuela Peixoto, Pedro Nobre
INTRODUCTION: Recent studies have demonstrated the role of sexual dysfunctional beliefs, negative automatic thoughts, and emotional responses in relation to sexual functioning. Nevertheless, no studies seem to have evaluated the role of these cognitive-emotional factors in determining sexual dissatisfaction. AIM: To test a cognitive-emotional model of sexual dissatisfaction in women. METHODS: In total, 207 women answered questionnaires assessing sexual dissatisfaction and cognitive and emotional variables that might affect sexual dissatisfaction...
November 2016: Journal of Sexual Medicine
https://www.readbyqxmd.com/read/27608416/acute-pulmonary-thromboembolism-in-emergency-room-gray-scale-versus-color-doppler-ultrasound-evaluation
#20
Maha Kamel Ghanem, Hoda Ahmed Makhlouf, Ali Abdel-Azeem Hasan, Ahmed Atef Alkarn
BACKGROUND: Pulmonary thromboembolism (PTE) remains under-diagnosed fatal disease at emergency units suggesting the need for alternative, easy, and noninvasive bedside diagnostic approaches. OBJECTIVES: To determine the diagnostic role of gray-scale and color Doppler transthoracic ultasonography (TUS) in patients with PTE. PATIENTS AND METHODS: Blinded to 64 multi-detectors CT pulmonary angiography (MDCTPA) examination as a gold standard, 60 patients with clinically suspected PTE underwent gray-scale and then color Doppler TUS examination...
September 8, 2016: Clinical Respiratory Journal
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