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perinatal psychiatric disorders

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https://www.readbyqxmd.com/read/28466069/early-social-isolation-stress-and-perinatal-nmda-receptor-antagonist-treatment-induce-changes-in-the-structure-and-neurochemistry-of-inhibitory-neurons-of-the-adult-amygdala-and-prefrontal-cortex
#1
Esther Castillo-Gómez, Marta Pérez-Rando, María Bellés, Javier Gilabert-Juan, José Vicente Llorens, Héctor Carceller, Clara Bueno-Fernández, Clara García-Mompó, Beatriz Ripoll-Martínez, Yasmina Curto, Noelia Sebastiá-Ortega, María Dolores Moltó, Julio Sanjuan, Juan Nacher
The exposure to aversive experiences during early life influences brain development and leads to altered behavior. Moreover, the combination of these experiences with subtle alterations in neurodevelopment may contribute to the emergence of psychiatric disorders, such as schizophrenia. Recent hypotheses suggest that imbalances between excitatory and inhibitory (E/I) neurotransmission, especially in the prefrontal cortex and the amygdala, may underlie their etiopathology. In order to understand better the neurobiological bases of these alterations, we studied the impact of altered neurodevelopment and chronic early-life stress on these two brain regions...
March 2017: ENeuro
https://www.readbyqxmd.com/read/28456376/-consultation-liaison-during-the-peripartum-network-care-between-liaison-and-mobile-unit
#2
V Garez, E Devouche, A Bobin-Bègue, M Alecian, P Minjollet, A Vallerent, M Poget, H Oguibenine, C Héroux, F Medjkane, G Apter
OBJECTIVES: The pregnancy periods of peripartum and immediate postpartum represent moments of opportunity to access care. Both prevention and therapeutic management can be offered with a better chance of success during these periods. Our specific Consultation Liaison (CL) team PPUMMA was created in order to respond to the need for early detection of psychopathology and rapid implementation of therapeutic management and preventive measure for mother and child. The importance of urgently intervening "on site" seemed a necessity since duration of hospitalization in maternity wards is very short...
April 26, 2017: L'Encéphale
https://www.readbyqxmd.com/read/28403471/do-psychiatric-disorders-or-measures-of-distress-moderate-response-to-postpartum-relapse-prevention-interventions
#3
Rachel P Kolko, Rebecca L Emery, Yu Cheng, Michele D Levine
Introduction: Most women who quit smoking during pregnancy will relapse postpartum. Interventions for sustained postpartum abstinence can benefit from understanding prenatal characteristics associated with treatment response. Given that individuals with psychiatric disorders or elevated depressive symptoms have difficulty quitting smoking and that increases in depressive symptoms prenatally are common, we examined the relevance of psychiatric diagnoses, prenatal depressive symptoms, and stress to postpartum relapse prevention intervention response...
May 1, 2017: Nicotine & Tobacco Research: Official Journal of the Society for Research on Nicotine and Tobacco
https://www.readbyqxmd.com/read/28347949/perinatal-and-postnatal-risk-factors-for-disruptive-mood-dysregulation-disorder-at-age-11-2004-pelotas-birth-cohort-study
#4
Tiago N Munhoz, Iná S Santos, Aluísio J D Barros, Luciana Anselmi, Fernando C Barros, Alicia Matijasevich
BACKGROUND: To date, there have been few studies of DMDD examining the risk factors during gestation and during the first years of life. We assessed the perinatal and postnatal risk factors associated with the occurrence of disruptive mood dysregulation disorder (DMDD) by 11 years of age. METHODS: Prospective longitudinal study. Mothers completed a standardized questionnaire shortly after childbirth. We used the Development and Well-Being Assessment, administered to the mothers or legal guardians, to identify DMDD among the 11-year-old subjects...
June 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/28314228/untreated-perinatal-paternal-depression-effects-on-offspring
#5
REVIEW
Salvatore Gentile, Maria Luigia Fusco
Transition to parenthood represents an important life event which increases vulnerability to psychological disorders. Aim of this article is to analyze all studies which investigated the effects of untreated perinatal paternal depression in offspring. We searched pertinent, peer-reviewed articles published in English (January 1980 to April 2016) on MEDLINE, PsycINFO, and Science.gov. Twenty-three studies met the inclusion criteria. Most of the reviewed studies suffer from methodological limitations, including the small sample, the lack of a structured psychiatric diagnosis, and inclusion bias...
June 2017: Psychiatry Research
https://www.readbyqxmd.com/read/28298276/early-life-nutritional-programming-of-cognition-the-fundamental-role-of-epigenetic-mechanisms-in-mediating-the-relation-between-early-life-environment-and-learning-and-memory-process
#6
REVIEW
Laura Moody, Hong Chen, Yuan-Xiang Pan
The perinatal period is a window of heightened plasticity that lays the groundwork for future anatomic, physiologic, and behavioral outcomes. During this time, maternal diet plays a pivotal role in the maturation of vital organs and the establishment of neuronal connections. However, when perinatal nutrition is either lacking in specific micro- and macronutrients or overloaded with excess calories, the consequences can be devastating and long lasting. The brain is particularly sensitive to perinatal insults, with several neurologic and psychiatric disorders having been linked to a poor in utero environment...
March 2017: Advances in Nutrition
https://www.readbyqxmd.com/read/28295746/post-traumatic-stress-disorder-in-the-perinatal-period-a-concept-analysis
#7
REVIEW
Julie Vignato, Jane M Georges, Ruth A Bush, Cynthia D Connelly
AIMS AND OBJECTIVES: To report an analysis of the concept of perinatal post-traumatic stress disorder. BACKGROUND: Prevalence of perinatal post-traumatic stress disorder is rising in the USA, with 9% of the U.S. perinatal population diagnosed with the disorder and an additional 18% being at risk for the condition. Left untreated, adverse maternal-child outcomes result in increased morbidity, mortality and healthcare costs. DESIGN: Concept analysis via Walker and Avant's approach...
March 15, 2017: Journal of Clinical Nursing
https://www.readbyqxmd.com/read/28242151/-viral-failure-in-infants-perinatally-infected-with-hiv-a-double-punishment
#8
N Trocmé, M-F Courcoux, M-D Tabone, F Hervé, E Bui, P Faucher, L Selleret, M-G Lebrette, G Leverger, C Dollfus
BACKGROUND: Considering the remarkable efficacy of the strategies for preventing mother-to-child transmission of HIV infection (PMTCT), failures are rare in high-resource countries and deserve further investigation. Moreover, infants have been found to be at increased risk of viral failure. We analyzed the factors related to the children's environment, including maternal psychological factors that may be associated with viral failure in children diagnosed before the age of 1 year. PATIENTS AND METHODS: Retrospective study of all HIV-infected infants, born in France between July 2003 and July 2013, diagnosed before the age of 1 year, cared for in a single reference center, comparing the group of children in viral success to the group of children presenting at least one episode of viral failure, using data available in their medical, psychological and social files...
February 24, 2017: Archives de Pédiatrie: Organe Officiel de la Sociéte Française de Pédiatrie
https://www.readbyqxmd.com/read/28229395/transcranial-magnetic-and-direct-current-stimulation-in-children
#9
REVIEW
Mustafa Q Hameed, Sameer C Dhamne, Roman Gersner, Harper L Kaye, Lindsay M Oberman, Alvaro Pascual-Leone, Alexander Rotenberg
Promising results in adult neurologic and psychiatric disorders are driving active research into transcranial brain stimulation techniques, particularly transcranial magnetic stimulation (TMS) and transcranial direct current stimulation (tDCS), in childhood and adolescent syndromes. TMS has realistic utility as an experimental tool tested in a range of pediatric neuropathologies such as perinatal stroke, depression, Tourette syndrome, and autism spectrum disorder (ASD). tDCS has also been tested as a treatment for a number of pediatric neurologic conditions, including ASD, attention-deficit/hyperactivity disorder, epilepsy, and cerebral palsy...
February 2017: Current Neurology and Neuroscience Reports
https://www.readbyqxmd.com/read/28203275/diagnostic-profiles-and-predictors-of-treatment-outcome-among-children-and-adolescents-attending-a-national-psychiatric-hospital-in-botswana
#10
Anthony A Olashore, Bechedza Frank-Hatitchki, Olorunfemi Ogunwobi
BACKGROUND: Attention is currently being drawn to child psychiatric care, most especially in the developed countries. This type of care is still rudimentary in the developing countries. Botswana is one of the African countries with good health care services but mental illness is given the low priority. Child and adolescent mental health care (CAMHC) is almost non-existent likely due to the dearth of research which would drive a policy change in this direction. Hence the need for this research as a step towards establishing a well-structured CAMHC...
2017: Child and Adolescent Psychiatry and Mental Health
https://www.readbyqxmd.com/read/28178739/methamphetamine-consumption-during-pregnancy-effects-on-child-health
#11
Jürgen Dinger, Patricia Hinner, Jörg Reichert, Mario Rüdiger
Methamphetamine abuse during pregnancy represents an emerging health care problem. The consequences are not only of relevance to the pregnant women, but also their unborn child. It is associated with an increased risk of preeclampsia and hypertension, fetal demise, preterm delivery, and intrauterine growth restriction. The deleterious effects of prenatal methamphetamine exposure on the developing fetal brain may lead to long-term neuro-developmental and behavioral problems.Given the current evidence, abuse of methamphetamine during pregnancy must be of utmost concern to health care professionals and to policy-makers...
May 2017: Pharmacopsychiatry
https://www.readbyqxmd.com/read/28160098/influence-of-exposure-to-perinatal-risk-factors-and-parental-mental-health-related-hospital-admission-on-adolescent-deliberate-self-harm-risk
#12
Nan Hu, Jianghong Li, Rebecca A Glauert, Catherine L Taylor
Adolescent deliberate self-harm (DSH) has been found to be associated with a range of bio-psycho-social factors. Simultaneous investigations of these factors enable more robust estimation of the independent effect of a specific risk factor by adjusting for a more complete set of covariates. However, few studies have had the ability to examine all of these factors together. This study used the linkage of population-level de-identified data collections from government agencies to investigate a range of biological, psychological, and social risk factors and their effects on adolescent risk of DSH (with or without suicidal intent)...
February 3, 2017: European Child & Adolescent Psychiatry
https://www.readbyqxmd.com/read/28122429/suspected-perinatal-depression-revealed-to-be-hereditary-diffuse-leukoencephalopathy-with-spheroids
#13
Josefine Blume, Robert Weissert
Early motor symptoms of neurodegenerative diseases often appear in combination with psychiatric symptoms, such as depression or personality changes, and are in danger of being misdiagnosed as psychogenic in young patients. We present the case of a 32-year-old woman who presented with rapid-onset depression, followed by a hypokinetic movement disorder and cognitive decline during pregnancy. Genetic testing revealed a mutation in the colony-stimulating factor 1 receptor gene, which led to the diagnosis of hereditary diffuse leukoencephalopathy with spheroids...
January 2017: Journal of Movement Disorders
https://www.readbyqxmd.com/read/28032214/perinatal-suicidal-ideation-and-behaviour-psychiatry-and-adversity
#14
Michael Nnachebe Onah, Sally Field, Jason Bantjes, Simone Honikman
Pregnant women are at increased risk for suicidal ideation and behaviours (SIB) compared to the general population. To date, studies have focused on the psychiatric correlates of SIB with lesser attention given to the associated contextual risk factors, particularly in low- and middle-income countries. We investigated the prevalence and associated psychiatric and socio-economic contextual factors for SIB among pregnant women living in low resource communities in South Africa. Three hundred seventy-six pregnant women were evaluated using a range of tools to collect data on socio-economic and demographic factors, social support, life events, interpersonal violence and mental health diagnoses...
April 2017: Archives of Women's Mental Health
https://www.readbyqxmd.com/read/28029515/the-polyenviromic-risk-score-aggregating-environmental-risk-factors-predicts-conversion-to-psychosis-in-familial-high-risk-subjects
#15
Jaya L Padmanabhan, Jai L Shah, Neeraj Tandon, Matcheri S Keshavan
BACKGROUND: Young relatives of individuals with schizophrenia (i.e. youth at familial high-risk, FHR) are at increased risk of developing psychotic disorders, and show higher rates of psychiatric symptoms, cognitive and neurobiological abnormalities than non-relatives. It is not known whether overall exposure to environmental risk factors increases risk of conversion to psychosis in FHR subjects. METHODS: Subjects consisted of a pilot longitudinal sample of 83 young FHR subjects...
March 2017: Schizophrenia Research
https://www.readbyqxmd.com/read/28000910/-environmental-and-genetic-variables-related-with-alterations-in-language-acquisition-in-early-childhood
#16
REVIEW
A Moriano-Gutierrez, J Colomer-Revuelta, J Sanjuan, J M Carot-Sierra
INTRODUCTION: A great deal of research has addressed problems in the correct acquisition of language, but with few overall conclusions. The reasons for this lie in the individual variability, the existence of different measures for assessing language and the fact that a complex network of genetic and environmental factors are involved in its development. AIM: To review the environmental and genetic variables that have been studied to date, in order to gain a better under-standing of the causes of specific language impairment and create new evidence that can help in the development of screening systems for the early detection of these disorders...
January 1, 2017: Revista de Neurologia
https://www.readbyqxmd.com/read/27916232/review-neuroinflammation-in-intrauterine-growth-restriction
#17
REVIEW
Julie A Wixey, Kirat K Chand, Paul B Colditz, S Tracey Bjorkman
Disruption to the maternal environment during pregnancy from events such as hypoxia, stress, toxins, inflammation, and reduced placental blood flow can affect fetal development. Intrauterine growth restriction (IUGR) is commonly caused by chronic placental insufficiency, interrupting supply of oxygen and nutrients to the fetus resulting in abnormal fetal growth. IUGR is a major cause of perinatal morbidity and mortality, occurring in approximately 5-10% of pregnancies. The fetal brain is particularly vulnerable in IUGR and there is an increased risk of long-term neurological disorders including cerebral palsy, epilepsy, learning difficulties, behavioural difficulties and psychiatric diagnoses...
November 25, 2016: Placenta
https://www.readbyqxmd.com/read/27914245/perinatal-hypothalamic-pituitary-adrenal-axis-regulation-among-women-with-eating-disorders-and-their-infants
#18
A Easter, E Taborelli, A Bye, P A Zunszain, C M Pariante, J Treasure, U Schmidt, N Micali
BACKGROUND: Psychiatric illness is associated with heightened hypothalamic-pituitary-adrenal (HPA) axis activity during pregnancy which may have long term effects on infant stress regulation. HPA axis regulation has not previously been investigated in women with eating disorders (ED) or their infants during the perinatal period. METHODS: Women were recruited to a prospective longitudinal study in three groups: 1) current or active ED (C-ED=31), 2) past ED (P-ED=29) and healthy control (HC=57)...
February 2017: Psychoneuroendocrinology
https://www.readbyqxmd.com/read/27889597/is-there-any-association-between-toxoplasma-gondii-infection-and-bipolar-disorder-a-systematic-review-and-meta-analysis
#19
João Luís Vieira Monteiro de Barros, Izabela Guimarães Barbosa, Haitham Salem, Natalia Pessoa Rocha, Arthur Kummer, Olaoluwa O Okusaga, Jair C Soares, Antonio Lucio Teixeira
BACKGROUND: The relationship between Toxoplasma gondii infection and the development of bipolar disorder (BD) has long been investigated, yet to date it is still poorly understood and documented. The aim of this review is to derive a summary estimate of the strength of the association between infection with T. gondii and BD from the available published studies. METHODS: A systematic review was performed using PubMed, LILACS, PsycINFO, and Embase databases. Studies which included a proportion of seropositive BD patients and controls were further examined in a meta-analysis...
February 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/27818357/the-role-of-neuropathological-markers-in-the-interpretation-of-neuropsychiatric-disorders-focus-on-fetal-and-perinatal-programming
#20
REVIEW
Fanni Daniela, Gerosa Clara, Rais Monica, Ravarino Alberto, Van Eyken Peter, Fanos Vassilios, Faa Gavino
The study of neuropathological markers in patients affected by mental/psychiatric disorders is relevant for the comprehension of the pathogenesis and the correlation with the clinical symptomatology. The neuropathology of Alzheimer's disease (AD) recognizes intraneuronal and extracellular neurofibrillary formation responsible for neuronal degeneration. Immunohistochemical studies discovered many interesting results for a better interpretation of the AD pathogenesis, while the "metal hypothesis" supports that metal ions might differentially influence the formation of amyloid aggregates...
November 3, 2016: Neuroscience Letters
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