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perinatal anxiety

Kylee Trevillion, Jill Domoney, Andrew Pickles, Debra Bick, Sarah Byford, Margaret Heslin, Jeannette Milgrom, Rachel Mycroft, Carmine Pariante, Elizabeth Ryan, Myra Hunter, Louise Michele Howard
BACKGROUND: Depression is a common antenatal mental disorder and is associated with an increased risk of adverse effects on the fetus and significant morbidity for the mother; if untreated it can also continue into the post-natal period and affect mother-infant interactions. There has been little research evaluating the effectiveness or cost-effectiveness of antenatal psychological interventions for antenatal depression, particularly for mild to moderate disorders. International guidelines recommend a stepped care approach starting with Guided Self Help, and the aim of this exploratory trial is to investigate Guided Self Help modified for pregnancy...
October 18, 2016: Trials
Siyang Yan, Amanda C Kentner
Exposure to painful procedures and/or stressors during the early neonatal period can reprogram the underlying neurocircuitry involved in nociception and neuropathic pain perception. The reprogramming of these systems can result in an enduring elevation in sensitivity towards mechanical and thermal stimuli. Recent evidence suggests that exposure to mild inflammatory mediators during the neonatal period can induce similar pain responses in both adolescent and adult rats. Therefore, we sought to profile changes in the expression of several genes across brain areas involved in the active modulation of nociception and neuropathic pain using a well-recognized model of neonatal inflammation...
October 11, 2016: Brain, Behavior, and Immunity
R M Dorman, L M Yee, S H Sutton
In our perinatal HIV cohort, we have observed difficulty swallowing pills as a frequent and significant barrier to adherence to highly active antiretroviral therapy. We refer to this problem as pill aversion and define it as difficulty swallowing pills with no persistent medical or structural cause as well as the anxiety and physical symptoms associated with pill swallowing. By applying cognitive behavioral theory to behavioral patterns within our pregnant HIV-infected population, we seek to better understand the development and reinforcement of pill aversion behavior...
October 13, 2016: Journal of Perinatology: Official Journal of the California Perinatal Association
Michael van Manen
Antenatal consultation is recognized as a core activity of specialists in neonatal-perinatal medicine. Fundamentally, the intent is for practitioner and parent to meet prior to the birth of a child to contribute to the care of the mother and also the newborn. Antenatal consults may therefore serve a multitude of purposes such as obtaining informed consent, relieving parental anxiety, elaborating medical treatment plans, and supporting parenting practices depending on the various situational and contextual factors underlying the consult...
October 11, 2016: Acta Paediatrica
Anthony P O'Brien, Karen A McNeil, Richard Fletcher, Agatha Conrad, Amanda J Wilson, Donovan Jones, Sally W Chan
More than 10% of fathers experience depression and anxiety during the perinatal period, but paternal perinatal depression (PPND) and anxiety have received less attention than maternal perinatal mental health problems. Few mainstream treatment options are available for men with PPND and anxiety. The aim of this literature review was to summarize the current understanding of PPND and the treatment programs specifically designed for fathers with perinatal depression. Eight electronic databases were searched using a predefined strategy, and reference lists were also hand searched...
September 29, 2016: American Journal of Men's Health
Anna L MacKinnon, Mariam Naguib, Helena J Barr, Anna Levinsson, Stephanie Robins, Nancy Feeley, Barbara Hayton, Phyllis Zelkowitz, Ian Gold
BACKGROUND: Despite the prevalence of mental health problems during the perinatal period, little research has examined psychotic symptoms in a community sample across pregnancy and the postpartum. Exposure to environmental risk factors, and immigration in particular, are associated with increased risk for psychotic disorders. The current investigation examined whether psychosocial risk and immigrant status would predict levels of delusional ideation across the perinatal period when controlling for depression, anxiety, and demographic factors...
September 23, 2016: Schizophrenia Research
Elizabeth Ford, Judy Shakespeare, Fatin Elias, Susan Ayers
BACKGROUND: Perinatal anxiety and depression are widespread, with up to 20% of women affected during pregnancy and after birth. In the UK, management of perinatal mental health falls under the remit of general practitioners (GPs). We reviewed the literature on GPs' routine recognition, diagnosis and management of anxiety and depression in the perinatal period. METHOD: A systematic search of Embase, Medline, PsycInfo, Pubmed, Scopus and Web of Science was conducted...
September 22, 2016: Family Practice
Oana M Blaga, Alexandra Brînzaniuc, Ioana A Rus, Răzvan M Cherecheș, Anne Baber Wallis
Perinatal smoking is associated with a wide range of negative reproductive and pregnancy outcomes. The aim of the current study was to examine the prevalence and characteristics of women who report smoking prenatally and quit during pregnancy in a large sample of Romanian women. Understanding which women are more likely to quit will contribute to public health knowledge that will help more women stop smoking prior to or during pregnancy and prevent relapse postpartum. This cross-sectional analysis was conducted based on cross-sectional data collected between May 2012 and April 2015 as part of a cohort study of pregnancy implemented in six clinical settings in central Romania (N = 2370)...
September 20, 2016: Journal of Community Health
Orly Sarid, Julie Cwikel, Johanna Czamanski-Cohen, Ephrat Huss
This paper presents an overview of a combined, evaluated protocol, cognitive behavioural and art therapy treatment (CB-ART), for the treatment of women with perinatal mood and anxiety disorders (PMADs). The protocol integrates cognitive behavioural interventions and art therapy. CB-ART focuses on changing distressing image, symptom or memory (ISM) that interferes with functioning. The method directs clients to identify compositional elements that characterize their stressful ISM and to alter the element in their imagination, in bodily sensations and on the page...
September 19, 2016: Archives of Women's Mental Health
Kelly E Ruhstaller, Michal A Elovitz, Marilyn Stringer, C Neill Eppersonmd, Celeste P Durnwald
OBJECTIVE: To evaluate the association between maternal obesity and mood disorders including depression, anxiety, stress and pregnancy specific stress during pregnancy. STUDY DESIGN: This was a planned secondary analysis of a prospective cohort study investigating factors associated with preterm delivery. The cohort included women who initiated prenatal care before 20 weeks with a singleton pregnancy. Maternal mental health was assessed using four standard psychosocial behavioral measures to screen for depression, pregnancy specific stress, anxiety and stress...
September 13, 2016: Journal of Maternal-fetal & Neonatal Medicine
Sigridur Sia Jonsdottir, Marga Thome, Thora Steingrimsdottir, Linda Bara Lydsdottir, Jon Fridrik Sigurdsson, Halldora Olafsdottir, Katarina Swahnberg
BACKGROUND: It is inferred that perinatal distress has adverse effects on the prospective mother and the health of the foetus/infant. More knowledge is needed to identify which symptoms of perinatal distress should be assessed during pregnancy and to shed light on the impact of women's satisfaction with their partner relationship on perinatal distress. AIM: The current study aimed to generate knowledge about the association of the partner relationship and social support when women are dealing with perinatal distress expressed by symptoms of depression, anxiety and stress...
September 5, 2016: Women and Birth: Journal of the Australian College of Midwives
I Tendais, B Figueiredo
STUDY QUESTION: Does mode of conception [spontaneous/after infertility treatment (IT)], type of pregnancy (singleton/twin) and parent gender have an effect on anxiety and depression levels and trajectories during pregnancy and the post-partum period? SUMMARY ANSWER: Conception after IT was associated with a transitory increase in anxiety during the perinatal period for parents of singletons, while for IT parents of twins higher levels of psychopathological symptoms tended to persist during pregnancy and the post-partum period...
October 2016: Human Reproduction
S A Johnson, A B Javurek, M S Painter, C R Murphy, C M Conard, K L Gant, E C Howald, M R Ellersieck, C E Wiedmeyer, V J Vieira-Potter, C S Rosenfeld
Maternal diet-induced obesity can cause detrimental developmental origins of health and disease in offspring. Perinatal exposure to a high-fat diet (HFD) can lead to later behavioral and metabolic disturbances, but it is not clear which behaviors and metabolic parameters are most vulnerable. To address this critical gap, biparental and monogamous oldfield mice (Peromyscus polionotus), which may better replicate most human societies, were used in the current study. About 2 weeks before breeding, adult females were placed on a control or HFD and maintained on the diets throughout gestation and lactation...
September 9, 2016: Journal of Developmental Origins of Health and Disease
Fay F Warnock, Kenneth D Craig, Roger Bakeman, Thaila Castral, Jila Mirlashari
BACKGROUND: Sensitive and responsive maternal caregiving behavior strengthens infant self-regulatory capacities (HL), but this regulatory role may be diminished in some mothers with second-trimester prenatal exposure to depression and/ or anxiety (MDA). This study examined maternal and infant behavior during infant heel lance (HL) when mothers had or did not have MDA. Ethological methods and micro-analytic approaches capable of distinguishing and comparing time-based patterning in maternal and infant behavior were used to clarify biological mechanisms, such as MDA, that may underlie observed behavior...
2016: BMC Pregnancy and Childbirth
Pablo Vázquez-Borsetti, Elena Peña, Catalina Rico, Mariana Noto, Nathalie Miller, Diego Cohon, Juan Manuel Acosta, Mariano Ibarra, Fabián C Loidl
Obstetrical complications of perinatal asphyxia (PA) can often induce lesions that, in the long-term, manifest as schizophrenia. A deterioration of the medial prefrontal cortex (mPFC) and a reduction in the number of GABAergic neurons are commonly observed in the pathophysiology of schizophrenia. In this study, we investigated the link between PA, reelin and calbindin diminution and psychiatric diseases that involve social interaction deficits. This was achieved by observing the effect of 19 min of asphyxia on both subpopulations of GABAergic neurons...
September 6, 2016: Developmental Neuroscience
Jenna L N Sprowles, Jillian R Hufgard, Arnold Gutierrez, Rebecca A Bailey, Sarah A Jablonski, Michael T Williams, Charles V Vorhees
Selective serotonin reuptake inhibitors (SSRIs) block the serotonin (5-HT) reuptake transporter (SERT) and increase synaptic 5-HT. 5-HT is also important in brain development; hence when SSRIs are taken during pregnancy there exists the potential for these drugs to affect CNS ontogeny. Prenatal SSRI exposure has been associated with an increased prevalence of autism spectrum disorder (ASD), and peripheral 5-HT is elevated in some ASD patients. Perinatal SSRI exposure in rodents has been associated with increased depression and anxiety-like behavior, decreased sociability, and impaired learning in the offspring, behaviors often seen in ASD...
November 2016: International Journal of Developmental Neuroscience
Victoria Fallon, Jason Christian Grovenor Halford, Kate Mary Bennett, Joanne Allison Harrold
Perinatal symptoms of anxiety are increasingly recognised due to their high prevalence and impact. Studies using pregnancy-specific anxiety measures have found that they may predict perinatal outcomes more effectively than general measures. However, no such measure exists to assess anxieties specific to the postpartum. This study aimed to develop and validate a measure (Postpartum Specific Anxiety Scale; PSAS) that accurately represents the specific anxieties faced by postpartum women, using a four-stage methodology: (1) 51 items were generated from interviews conducted with a group of 19 postpartum women at two time points, (2) the scale was reviewed and refined by a diverse expert panel, (3) an online pilot study (n = 146) was conducted to assess comprehensibility and acceptability and (4) an online sample of 1282 mothers of infants up to 6 months old completed the PSAS against a battery of convergent measures...
August 29, 2016: Archives of Women's Mental Health
I Capponi, P Carquillat, Å Premberg, F Vendittelli, M-J Guittier
OBJECTIVES: For fathers, being present at a birth for the first time is not an insignificant event. Witnessing suffering can cause feelings of loneliness and powerlessness, which may be associated with postnatal problems such as depression. However, without a confirmed French-language tool concerning the experience of childbirth for fathers, we are limited in our ability to develop our understanding of their experiences and establish links between these experiences and their distress (anxiety, depression, etc...
September 2016: Gynécologie, Obstétrique & Fertilité
Dominic Vogt, Sandra Waeldin, Dirk Hellhammer, Gunther Meinlschmidt
Pre-, peri-, and postnatal stress have frequently been reported to be associated with negative health outcomes during adult life. However, it is unclear, if these factors independently predict mental health in adulthood. We estimated potential associations between reports of pre-, peri-, and postnatal stress and depression severity in outpatients (N = 473) diagnosed with depression, anxiety or somatoform disorders by their family physician. We retrospectively assessed pre-, peri-, and postnatal stress and measured depression severity as well as recent life stress using questionnaires...
August 7, 2016: Journal of Psychiatric Research
Laura M Belluscio, Carolina D Alberca, Nicolás Pregi, Eduardo T Cánepa
Perinatal development represents a critical period in the life of an individual. A common cause of poor development is that which comes from undernutrition or malnutrition. In particular, protein deprivation during development has been shown to have deep deleterious effects on brain's growth and plasticity. Early life stress has also been linked with an increased risk to develop different psychopathologies later in life. We have previously shown that perinatal protein malnutrition in mice leads to the appearance of anxiety-related behaviors in the adulthood...
August 24, 2016: Genes, Brain, and Behavior
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