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https://www.readbyqxmd.com/read/27538058/advances-in-serological-diagnostics-of-inflammatory-myopathies
#1
Olivier Benveniste, Werner Stenzel, Yves Allenbach
PURPOSE OF REVIEW: Inflammatory myopathies are rare diseases. Their diagnosis criteria are historically based on their clinical phenotype (topography of the muscle weakness, presence of skin lesions and/or of extra-skin/muscle signs) and the presence of inflammatory infiltrates on muscle biopsy. However, the recent discovery of different myositis-specific antibodies (MSA) or myositis-associated antibodies (MAA) permitted to revisit these old classifications. This review covers recent findings in clinical and pathological phenotypes regarding prognosis, associated cancer and response to the treatment based on MSA/MAA categorization...
October 2016: Current Opinion in Neurology
https://www.readbyqxmd.com/read/25528800/-esophageal-motor-disturbances-in-sclerodermia
#2
C Stanciu, C Cijevschi, A Dobrescu, Z Petrescu
By the manometric method the esophageal motility in 14 patients with sclerodermia was studied. All patients presented an esophageal motor dysfunction characterized by the decrease in amplitude of the spohageal contractions, presence of aperistaltic contractions, decrease of basal pressure of the lower esophageal sphincter and its incomplete relaxation at deglutition. These esophageal motor disturbances may appear in association or separately in the same patient. The pathogenesis of the esophageal motor dysfunction in sclerodermia is not yet fully understood...
October 1981: Revista Medico-chirurgicală̆ a Societă̆ţ̜ii de Medici ş̧i Naturaliş̧ti Din Iaş̧i
https://www.readbyqxmd.com/read/25501010/haemosiderin-laden-sputum-macrophages-for-diagnosis-in-pulmonary-veno-occlusive-disease
#3
Heidi Lederer, Bettina Muggli, Rudolf Speich, Ula Treder, Hans Stricker, Jeroen Goede, Silvia Ulrich, Simon F Stämpfli, Alexander Breitenstein
AIMS: Pulmonary veno-occlusive disease (PVOD) is a rare condition of pulmonary arterial hypertension (PAH), in which post-capillary veins are affected. Since the therapeutic approach in PVOD differs from other forms of PAH, it is crucial to establish the diagnosis. Due to the fact that affected patients are often hemodynamically unstable, minimal invasive procedures are necessary for the diagnostic work-up. Chronic alveolar haemorrhage has been observed during bronchoalveolar lavage in PVOD cases...
2014: PloS One
https://www.readbyqxmd.com/read/25315720/-renal-and-extra-renal-involvement-in-sclerodermia
#4
Luca Visconti, Marco Atteritano, Michele Buemi, Domenico Santoro
Scleroderma or systemic sclerosis (SSc) is an autoimmune disease of the connective tissue, characterized by vascular abnormalities and progressive fibrosis of the skin and internal organs. Kidney, esophagus, heart and lung are most frequently involved. According to the extensive skin involvement and the internal organ injury, scleroderma is classified in limited and diffuse forms. Vascular injury is considered the first event in the pathogenesis of scleroderma. Vasculopathy primarily affects the microcirculation and the small vessels decreasing blood flow that results in chronic ischemia...
September 2014: Giornale Italiano di Nefrologia: Organo Ufficiale Della Società Italiana di Nefrologia
https://www.readbyqxmd.com/read/23882932/-reversible-pulmonary-hypertension-as-a-consequence-of-dasatinib-treatment-in-a-patient-with-chronic-myeloid-leukemia-and-scleroderma
#5
Robert Ryczek, Joanna Góra-Tybor, Katarzyna Betkier-Lipińska, Andrzej Cwetsch
Pulmonary hypertension may be associated with many clinical conditions, including connective tissue diseases. We present a case of a patient with sclerodermia and chronic myeloid leukemia, who developed severe symptoms of pulmonary hypertension. Atypical clinical course of pulmonary hypertension, including complete remission of clinical symptoms and hemodynamic improvement provoked critical approach to the etiology of pulmonary hypertension. Taking into account the temporal coincidence with the use of dasatinib (a tyrosine kinase inhibitor) and a few case reports in the literature, it appears that reversible pulmonary hypertension in our patient was associated with the use of dasatinib...
June 2013: Polski Merkuriusz Lekarski: Organ Polskiego Towarzystwa Lekarskiego
https://www.readbyqxmd.com/read/22998975/-acquired-necrotizing-myopathies
#6
Y Allenbach, O Benveniste
Necrotizing myopathies (MN) are defined by a specific histological pattern. They are characterized by a predominant muscle fibre necrosis and regeneration but with little or no associated inflammation. This histological pattern is observed in acquired myopathy but also in muscular dystrophy. Acquired NM can be secondary to drugs or toxics, and if not, autoimmune mechanisms have to be suspected. Necrotizing autoimmune myopathy is recognized as a subgroup of idiopathic inflammatory myopathies, different from other myositides...
June 2013: La Revue de Médecine Interne
https://www.readbyqxmd.com/read/22691207/best-practices-in-scleroderma-an-analysis-of-practice-variability-in-ssc-centres-within-the-canadian-scleroderma-research-group-csrg
#7
Sarah Harding, Sarit Khimdas, Ashley Bonner, Murray Baron, Janet Pope
OBJECTIVES: There is currently no consensus on best practice in systemic sclerosis (SSc). To determine if variability in treatment and investigations exists, practices among Canadian Sclerodermia Research Group (CSRG) centres were compared. METHODS: Prospective clinical and demographic data from adult SSc patients are collected annually from 15 CSRG treatment centres. Laboratory parameters, self-reported socio-demographic questionnaires, current and past medications and disease outcome measures are recorded...
March 2012: Clinical and Experimental Rheumatology
https://www.readbyqxmd.com/read/21734340/correlation-between-eicosanoids-in-bronchoalveolar-lavage-fluid-and-in-exhaled-breath-condensate
#8
COMPARATIVE STUDY
Adam Antczak, Wojciech Piotrowski, Jerzy Marczak, Maciej Ciebiada, Pawel Gorski, Peter J Barnes
Exhaled breath condensate (EBC) has been increasingly used as a new and non-invasive method to study airway inflammation. In this study we have compared the concentrations of lipid mediators in EBC with concentrations in bronchoalveolar lavage fluid (BALF). We included 37 patients undergoing bronchoscopy (12 sarcoidosis, 12 COPD, 6 lung cancer, 5 chronic cough, 1 Wegener's granulomatosis, 1 sclerodermia). Patients were not allowed to have exacerbation or any change in concomitant medication for at least 4 weeks prior to the study...
2011: Disease Markers
https://www.readbyqxmd.com/read/20915483/sclerodermia-or%C3%A2-scleropanniculomyodermia
#9
W N Goldsmith
No abstract text is available yet for this article.
April 1937: Proceedings of the Royal Society of Medicine
https://www.readbyqxmd.com/read/20906633/case-of-unilateral-morph%C3%A5-o-sclerodermia-faciei
#10
G Pernet
No abstract text is available yet for this article.
1922: Proceedings of the Royal Society of Medicine
https://www.readbyqxmd.com/read/20904761/case-of-unilateral-band-sclerodermia-and-morph%C3%A5-osclerodermia-of-the-left-leg
#11
G Pernet
No abstract text is available yet for this article.
1919: Proceedings of the Royal Society of Medicine
https://www.readbyqxmd.com/read/20904401/case-of-multiple-morph%C3%A5-o-sclerodermia
#12
G Pernet
No abstract text is available yet for this article.
1918: Proceedings of the Royal Society of Medicine
https://www.readbyqxmd.com/read/20904020/case-of-morph%C3%A5-o-sclerodermia
#13
G Pernet
No abstract text is available yet for this article.
1917: Proceedings of the Royal Society of Medicine
https://www.readbyqxmd.com/read/20904015/case-of-%C3%A5-dematous-sclerodermia
#14
J M Macleod
No abstract text is available yet for this article.
1917: Proceedings of the Royal Society of Medicine
https://www.readbyqxmd.com/read/20904007/case-of-circumscribed-sclerodermia-morph%C3%A5-a-in-a-child
#15
J H Stowers
No abstract text is available yet for this article.
1917: Proceedings of the Royal Society of Medicine
https://www.readbyqxmd.com/read/20903546/sclerodermia-associated-with-graves-s-disease-and-later-myx%C3%A5-dema-conspicuously-benefiting-by-implantation-of-human-thyroid-into-the-bone-marrow
#16
(no author information available yet)
No abstract text is available yet for this article.
1916: Proceedings of the Royal Society of Medicine
https://www.readbyqxmd.com/read/20903534/case-of-morph%C3%A5-o-sclerodermia-shown-before-with-recent-acute-symmetrical-involvement-of-the-soles-of-the-feet
#17
G Pernet
No abstract text is available yet for this article.
1916: Proceedings of the Royal Society of Medicine
https://www.readbyqxmd.com/read/20903532/sclerodermia-occurring-in-a-case-of-myx%C3%A5-dema-while-under-thyroid-treatment
#18
J H Sequeira
No abstract text is available yet for this article.
1916: Proceedings of the Royal Society of Medicine
https://www.readbyqxmd.com/read/20903038/morph%C3%A5-ic-sclerodermia
#19
W K Sibley
No abstract text is available yet for this article.
1915: Proceedings of the Royal Society of Medicine
https://www.readbyqxmd.com/read/20902977/morph%C3%A5-ic-sclerodermia
#20
G Pernet
No abstract text is available yet for this article.
1915: Proceedings of the Royal Society of Medicine
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