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Sophie Robinson, David W Kissane, Joanne Brooker, Courtney Hempton, Susan Burney
CONTEXT: The risk of suicide is elevated in palliative care patients compared to the general population. Various psychological factors, including depression, demoralization, loss of control, and low self-worth have been associated with a desire to hasten death. OBJECTIVES: The aim of this study was to investigate whether depression, demoralization, loss of control, and low self-worth mediated the relationship between global quality of life and desire to hasten death...
October 12, 2016: Journal of Pain and Symptom Management
Isabella E Romero, Nasreen Toorabally, Danielle Burchett, Anthony M Tarescavage, David M Glassmire
Contemporary models of psychopathology-encompassing internalizing, externalizing, and thought dysfunction factors-have gained significant support. Although research indicates the Minnesota Multiphasic Personality Inventory-2 Restructured Form (MMPI-2-RF; Ben-Porath & Tellegen, 2008 /2011) measures these domains of psychopathology, this study addresses extant limitations in MMPI-2-RF diagnostic validity research by examining associations between all MMPI-2-RF substantive scales and broad dichotomous indicators of internalizing, externalizing, and thought dysfunction diagnoses in a sample of 1,110 forensic inpatients...
September 23, 2016: Journal of Personality Assessment
Thomas J Yager, Nicole Gerszberg, Bruce P Dohrenwend
This research focused on secondary traumatization of wives and offspring of 115 male Vietnam veterans, a subsample from the National Vietnam Veterans Readjustment Study who had one or more children aged 6 to 16 years and had had a clinical interview. Traumatization was defined as meeting criteria for lifetime war-related posttraumatic stress disorder (PTSD). Secondary traumatization was operationalized by elevated scores on children's internalizing or externalizing behavior problems and on wives' demoralization...
August 2016: Journal of Traumatic Stress
A Charmillon, E Novy, N Agrinier, M Leone, A Kimmoun, B Levy, B Demoré, J Dellamonica, C Pulcini
No abstract text is available yet for this article.
June 2016: Médecine et Maladies Infectieuses
Ann L Charrette, Laura S Lorenz, Jeffrey Fong, Therese M O'Neil-Pirozzi, Karen Lamson, Michelle Demore-Taber, Ross Lilley
BACKGROUND AND PURPOSE: Effects of high-intensity exercise on endurance, mobility and gait speed of adults with chronic moderate-to-severe acquired brain injury (ABI) were investigated. It was hypothesized that intensive exercise would be associated with improvements in impairment and activity limitation measures. PARTICIPANTS: Fourteen adults with chronic ABI in supported independent living who could stand with minimal or no assist and walk with or without ambulation device were studied...
2016: Brain Injury: [BI]
Andrew R Block
It is now well established that psychosocial factors can adversely impact the outcome of spine surgery. This article discusses in detail one such recently-identified "risk" factor: demoralization. Several studies conducted by the author indicate that demoralization, an emotional construct distinct from depression, is associated with poorer pain reduction, less functional improvement and decreased satisfaction among spine surgery patients. However, there are indications that the adverse impact of risk factors such as demoralization can be mitigated by psychosocial "maximizing" factors-characteristics that propel the patient towards positive surgical results...
2016: Healthcare (Basel, Switzerland)
Eleanor Shkalim, Moshe Almagor, Yossef S Ben-Porath
Watson ( 2005 ) proposed a hierarchical reorganization of the underlying structure of emotional disorders. This study cross-culturally evaluated Watson's (2005) structure of mood and anxiety disorders, using mainly dichotomous criteria, and explored the placement of obsessive-compulsive disorder (OCD) in this model. It also tested Sellbom, Ben-Porath, and Bagby's (2008) proposed elaboration of the 2-factor model (positive and negative activation) that incorporates a higher order dimension of demoralization...
June 22, 2016: Journal of Personality Assessment
Sara Gostoli, Renzo Roncuzzi, Stefano Urbinati, Donald E Morisky, Chiara Rafanelli
OBJECTIVE: Cardiac rehabilitation (CR) is considered the recommended secondary prevention treatment for cardiovascular diseases (CVD), in terms of health behaviours and, secondarily, better cardiac outcomes promotion. However, the role of psychiatric and psychosomatic distress on the efficacy of CR is unclear. This research aimed to evaluate the impact of CR on unhealthy behaviour modification and cardiac course, considering the moderating role of depression, anxiety, and psychosomatic syndromes...
June 18, 2016: British Journal of Health Psychology
Emanuela Offidani, Donatella Del Basso, Francesca Prignago, Elena Tomba
Psoriasis is a chronic dermatologic disease that negatively impacts physical and mental health of patients as well as their social and work life. The aim of this study is to illustrate, by a clinimetric approach the differences in psychological distress and well-being between patients with mild and moderate to severe psoriasis. Seventy patients with psoriasis were evaluated using the Structured Clinical Interview for DSM-IV (SCID-I), the Diagnostic Criteria for Psychosomatic Research (DCPR), along with the following self-report instruments: the Symptoms Questionnaire (SQ), the Psychological Well-being scales (PWB) and the Temperament and Character Inventory (TCI)...
August 23, 2016: Acta Dermato-venereologica
Katherine McKenzie, Hélène Ouellette-Kuntz, Ashleigh Blinkhorn, Ashley Démoré
BACKGROUND: The transition period out of the educational system can be a source of stress for parents of young adults with intellectual and developmental disabilities, as families lose the support and respite offered by schools. MATERIALS AND METHODS: Using a before and after design nested within a 24-month follow-up study of parents seeking adult developmental services for their children, parents' perception of distress was measured using the Brief Family Distress Scale (Journal of Child and Family Studies, 20, 2011, 521) and their perception of helpfulness of formal supports was assessed using the Family Support Scale (Journal of Individual, Family, and Community Wellness, 1, 1984, 45)...
June 9, 2016: Journal of Applied Research in Intellectual Disabilities: JARID
Chih-Cheng Chang, Tsung-Hsien Wu, Chih-Yin Chen, Chung-Ying Lin
Internalized stigma (or self-stigma), one of the most painful effects of stigma, causes people with mental health problems profound negative consequences, for example, psychological adversity, demoralization, and feelings of hopelessness. However, knowledge about self-stigma in people with different mental disorders is insufficient. We hypothesized that people with different psychiatric diagnoses have different levels of self-stigma. Through convenience sampling, we used the Internalized Stigma of Mental Illness Scale to compare people diagnosed with schizophrenia (n = 161), depressive disorder (n = 98), bipolar disorder (n = 43), and anxiety disorder (n = 45) in southern Taiwan...
July 2016: Journal of Nervous and Mental Disease
Syed Mahboob, Rachael McPhillips, Zhen Qiu, Yun Jiang, Carl Meggs, Giuseppe Schiavone, Tim Button, Marc Desmulliez, Christine Demore, Sandy Cochran, Sam Eljamel
BACKGROUND: Image-guided surgery has become standard practice during surgical resection, using preoperative magnetic resonance imaging. Intraoperative ultrasound (IoUS) has attracted interest because of its perceived safety, portability, and real-time imaging. This report is a meta-analysis of intraoperative ultrasound in gliomas. METHODS: Critical literature review and meta-analyses, using the MEDLINE/PubMed service. The list of references in each article was double-checked for any missing references...
August 2016: World Neurosurgery
Luigi Grassi, Maria Giulia Nanni
No abstract text is available yet for this article.
July 15, 2016: Cancer
Sophie Robinson, David W Kissane, Joanne Brooker, Natasha Michael, Jane Fischer, Michael Franco, Courtney Hempton, Merlina Sulistio, Julie F Pallant, David M Clarke, Susan Burney
BACKGROUND: The Demoralization Scale (DS) was initially validated in 2004 to enable the measurement of demoralization in patients with advanced cancer. Subsequent shortcomings indicated the need for psychometric strengthening. Here, the authors report on the refinement and revalidation of the DS to form the DS-II, specifically reporting the scale's internal validity. METHODS: Patients with cancer or other progressive diseases who were receiving palliative care (n = 211) completed a revised version of the 24-item DS and a measure of symptom burden (the Memorial Symptom Assessment Scale)...
July 15, 2016: Cancer
Sophie Robinson, David W Kissane, Joanne Brooker, Courtney Hempton, Natasha Michael, Jane Fischer, Michael Franco, Merlina Sulistio, David M Clarke, Mehmet Ozmen, Susan Burney
BACKGROUND: The recently refined Demoralization Scale-II (DS-II) is a 16-item, self-report measure of demoralization. Its 2 factors-Meaning and Purpose and Distress and Coping Ability-demonstrate sound internal validity, including item fit, unidimensionality, internal consistency, and test-retest reliability. The convergent and discriminant validity of the DS-II with various measures is reported here. METHODS: Patients who had cancer or other progressive diseases and were receiving palliative care (n = 211) completed a battery of questionnaires, including the DS-II and measures of symptom burden, quality of life, depression, and attitudes toward the end of life...
July 15, 2016: Cancer
A Charmillon, E Novy, N Agrinier, M Leone, A Kimmoun, B Levy, B Demoré, J Dellamonica, C Pulcini
Our objective was to assess current practices about the administration (intermittent, extended, or continuous infusions) and therapeutic drug monitoring (TDM) of β-lactam antibiotics and vancomycin in France. We conducted a nationwide cross-sectional survey in May-August 2015, using an online questionnaire, sent as an e-mail link to infectious disease specialists and intensive care specialists through national mailing lists. We used clinical vignettes of critically ill patients to assess physicians' practices about administration and TDM practices for amoxicillin, cloxacillin, piperacillin/tazobactam, cefotaxime, ceftazidime, cefepime, meropenem and vancomycin...
July 2016: Clinical Microbiology and Infection
Christopher A Fama, Nita Chen, Julia Prusik, Vignessh Kumar, Meghan Wilock, Steven Roth, Julie G Pilitsis
BACKGROUND: Pre-operative psychological assessment is commonly used to assess patients for spinal cord stimulation (SCS). Though often times mandated by insurance, its value is frequently questioned. METHODS: We review the literature on the predictive value of psychological testing prior to SCS and retrospectively examine our prospective database of SCS patients. We examine associations of Minnesota Multiphasic Personality Inventory (MMPI), Beck Depression Inventory (BDI), and Pain Catastrophizing Scale (PCS) findings and outcomes on the visual analog scale (VAS), McGill Pain Questionnaire - Short Form (MPQ), and Oswestry Disability Index (ODI) at 6 and 12 months post-implantation...
June 2016: Neuromodulation: Journal of the International Neuromodulation Society
Zhen Qiu, Yongqiang Qiu, Christine E M Demore, Sandy Cochran
The higher performance of relaxor-based piezocrystals compared with piezoceramics is now well established, notably including improved gain-bandwidth product, and these materials have been adopted widely for biomedical ultrasound imaging. However, their use in other applications, for example as a source of focused ultrasound for targeted drug delivery, is hindered in several ways. One of the issues, which we consider here, is in shaping the material into the spherical geometries used widely in focused ultrasound...
July 2016: Ultrasonics
W W T Lam, S W Yoon, W K Sze, A W Y Ng, I Soong, A Kwong, D Suen, J Tsang, W Yeo, K Y Wong, R Fielding
BACKGROUND: Most women with advanced breast cancer (ABC) show little distress, but about one in ten show persistent distress over time. It remains unclear if meanings ascribed by patients to ABC differentiate these distress trajectories. STUDY AIMS: This qualitative study (a) compared illness meanings of ABC between women with persistent psychological distress and those with low/transient distress, and (b) examined how illness meanings might influence coping strategies...
April 6, 2016: Psycho-oncology
Matthew J Billard, David J Fitzhugh, Joel S Parker, Jaime M Brozowski, Marcus W McGinnis, Roman G Timoshchenko, D Stephen Serafin, Ruth Lininger, Nancy Klauber-Demore, Gary Sahagian, Young K Truong, Maria F Sassano, Jonathan S Serody, Teresa K Tarrant
Triple negative breast cancer (TNBC) is a heterogeneous disease that has a poor prognosis and limited treatment options. Chemokine receptor interactions are important modulators of breast cancer metastasis; however, it is now recognized that quantitative surface expression of one important chemokine receptor, CXCR4, may not directly correlate with metastasis and that its functional activity in breast cancer may better inform tumor pathogenicity. G protein coupled receptor kinase 3 (GRK3) is a negative regulator of CXCR4 activity, and we show that GRK expression correlates with tumorigenicity, molecular subtype, and metastatic potential in human tumor microarray analysis...
2016: PloS One
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