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https://www.readbyqxmd.com/read/28505989/pediatric-robotic-rehabilitation-current-knowledge-and-future-trends-in-treating-children-with-sensorimotor-impairments
#1
Konstantinos P Michmizos, Hermano Igo Krebs
BACKGROUND: Robot-aided sensorimotor therapy imposes highly repetitive tasks that can translate to substantial improvement when patients remain cognitively engaged into the clinical procedure, a goal that most children find hard to pursue. Knowing that the child's brain is much more plastic than an adult's, it is reasonable to expect that the clinical gains observed in the adult population during the last two decades would be followed up by even greater gains in children. Nonetheless, and despite the multitude of adult studies, in children we are just getting started: There is scarcity of pediatric robotic rehabilitation devices that are currently available and the number of clinical studies that employ them is also very limited...
May 11, 2017: NeuroRehabilitation
https://www.readbyqxmd.com/read/28505988/intensive-seated-robotic-training-of-the-ankle-in-patients-with-chronic-stroke-differentially-improves-gait
#2
Johanna L Chang, Regina Y Lin, Maira Saul, Philip J Koch, Hermano Igo Krebs, Bruce T Volpe
BACKGROUND: Robotic driven treatment plans targeting isolated joints of the upper limb have improved the sensorimotor condition of patients with stroke. Similar intensive efforts to allay lower limb gait impairment have not been so successful. In patients with stroke, targeted robot assisted training of the ankle joint, in a seated position, has demonstrated significant alterations in ankle stiffness and foot-ankle orientation at foot strike which may provide a new treatment option for gait impairment...
May 10, 2017: NeuroRehabilitation
https://www.readbyqxmd.com/read/28499951/effects-of-task-specific-rehabilitation-training-on-tau-modification-in-rat-with-photothrombotic-cortical-ischemic-damage
#3
Kyung-Lim Joa, Sohee Moon, Ji-Hye Kim, Dong Wun Shin, Kyoung-Hee Lee, Seon Jung, Myeong-Ok Kim, Chang-Hwan Kim, Han-Young Jung, Ju-Hee Kang
Although stroke elicits progressive cognitive decline and is a leading cause of dementia, molecular interplay between stroke and Alzheimer's disease (AD) pathology has not been fully elucidated. Furthermore, studies on the effects of post-stroke rehabilitation on AD pathology are limited. We evaluated the acute effect of stroke on tau modification, and the molecular effects of task-specific training (TST) on tau modification using a model of photochemically-induced thrombosis (PIT)-induced cortical infarction...
May 9, 2017: Neurochemistry International
https://www.readbyqxmd.com/read/28488937/traditional-balance-and-slackline-training-are-associated-with-task-specific-adaptations-as-assessed-with-sensorimotor-tests
#4
Samuel Volery, Navrag Singh, Eling D de Bruin, Renate List, Marc Morten Jaeggi, Brigitte Mattli Baur, Silvio Lorenzetti
The purpose of this study was to measure alterations in sensorimotor skills and balance resulting from slackline training and conventional balance training. Forty-three physically fit subjects were randomized into three groups. Two groups practiced three times a week for 15 minutes, including at least once supervised session, on the slackline or perform conventional balance training for 6 weeks. The control group was not allowed to perform any balance training. Before and after the intervention, the subjects underwent sensorimotor and strength tests...
May 10, 2017: European Journal of Sport Science
https://www.readbyqxmd.com/read/28487626/continuous-auditory-feedback-of-eye-movements-an-exploratory-study-toward-improving-oculomotor-control
#5
Eric O Boyer, Arthur Portron, Frederic Bevilacqua, Jean Lorenceau
As eye movements are mostly automatic and overtly generated to attain visual goals, individuals have a poor metacognitive knowledge of their own eye movements. We present an exploratory study on the effects of real-time continuous auditory feedback generated by eye movements. We considered both a tracking task and a production task where smooth pursuit eye movements (SPEM) can be endogenously generated. In particular, we used a visual paradigm which enables to generate and control SPEM in the absence of a moving visual target...
2017: Frontiers in Neuroscience
https://www.readbyqxmd.com/read/28479473/using-guitar-learning-to-probe-the-action-observation-network-s-response-to-visuomotor-familiarity
#6
Tom Gardner, Aidas Aglinskas, Emily S Cross
Watching other people move elicits engagement of a collection of sensorimotor brain regions collectively termed the Action Observation Network (AON). An extensive literature documents more robust AON responses when observing or executing familiar compared to unfamiliar actions, as well as a positive correlation between amplitude of AON response and an observer's familiarity with an observed or executed movement. On the other hand, emerging evidence shows patterns of AON activity counter to these findings, whereby in some circumstances, unfamiliar actions lead to greater AON engagement than familiar actions...
May 4, 2017: NeuroImage
https://www.readbyqxmd.com/read/28479322/spike-timing-matters-in-novel-neuronal-code-involved-in-vibrotactile-frequency-perception
#7
Ingvars Birznieks, Richard M Vickery
Skin vibrations sensed by tactile receptors contribute significantly to the perception of object properties during tactile exploration [1-4] and to sensorimotor control during object manipulation [5]. Sustained low-frequency skin vibration (<60 Hz) evokes a distinct tactile sensation referred to as flutter whose frequency can be clearly perceived [6]. How afferent spiking activity translates into the perception of frequency is still unknown. Measures based on mean spike rates of neurons in the primary somatosensory cortex are sufficient to explain performance in some frequency discrimination tasks [7-11]; however, there is emerging evidence that stimuli can be distinguished based also on temporal features of neural activity [12, 13]...
May 3, 2017: Current Biology: CB
https://www.readbyqxmd.com/read/28475061/modulation-of-parkinsonian-state-with-uncertain-disturbance-based-on-sliding-mode-control
#8
Yulin Zhu, Jiang Wang, Huiyan Li, Bin Deng, Chen Liu
Parkinson's disease (PD) is a degenerative disorder of central nervous system that endangers the olds' health seriously. The motor symptoms of PD can be attributed to the distorted relay reliability of thalamus to cortical sensorimotor input that results from the increase of inhibitory input from internal segment of the globus pallidum (GPi). Based on this, we construct the GPithalamocortical computational model to generate the normal and pathological firing patterns by varying GPi spike train input. A kind of closed-loop deep brain stimulation (DBS) strategy is proposed here...
May 2, 2017: IEEE Transactions on Neural Systems and Rehabilitation Engineering
https://www.readbyqxmd.com/read/28467317/deep-learning-based-artificial-vision-for-grasp-classification-in-myoelectric-hands
#9
Ghazal Ghazaei, Ali Alameer, Patrick Degenaar, Graham Morgan, Kianoush Nazarpour
OBJECTIVE: Computer vision-based assistive technology solutions can revolutionise the quality of care for people with sensorimotor disorders. The goal of this work was to enable trans-radial amputees to use a simple, yet efficient, computer vision system to grasp and move common household objects with a two-channel myoelectric prosthetic hand. APPROACH: We developed a deep learning-based artificial vision system to augment the grasp functionality of a commercial prosthesis...
May 3, 2017: Journal of Neural Engineering
https://www.readbyqxmd.com/read/28453452/the-efficacy-of-a-huber-exercise-system-mediated-sensorimotor-training-protocol-on-proprioceptive-system-lumbar-movement-control-and-quality-of-life-in-patients-with-chronic-non-specific-low-back-pain
#10
Amir Letafatkar, Maryam Nazarzadeh, Malihe Hadadnezhad, Niloufar Farivar
BACKGROUND: There is a relation between deficits of the proprioceptive system and movement control dysfunction in patients with chronic low back pain (LBP) but, the exact mechanism of this relation is unknown. Exercise therapy has been recognized as an effective method for low back pain treatment. In spite of this, it is not clear which of the various exercise therapy programs lead to better results. OBJECTIVE: Therefore, the present analyze the efficacy of a HUBER study aims to exercise system mediated sensorimotor training protocol on proprioceptive system, lumbar movement control (LMC) and quality of life (QOL) in patients with chronic non-specific LBP...
April 21, 2017: Journal of Back and Musculoskeletal Rehabilitation
https://www.readbyqxmd.com/read/28442945/pulse-train-stimulation-of-primary-somatosensory-cortex-blocks-pain-perception-in-tail-clip-test
#11
Soohyun Lee, Eunjin Hwang, Dongmyeong Lee, Jee Hyun Choi
Human studies of brain stimulation have demonstrated modulatory effects on the perception of pain. However, whether the primary somatosensory cortical activity is associated with antinociceptive responses remains unknown. Therefore, we examined the antinociceptive effects of neuronal activity evoked by optogenetic stimulation of primary somatosensory cortex. Optogenetic transgenic mice were subjected to continuous or pulse-train optogenetic stimulation of the primary somatosensory cortex at frequencies of 15, 30, and 40 Hz, during a tail clip test...
April 2017: Experimental Neurobiology
https://www.readbyqxmd.com/read/28440338/unravelling-the-contributions-of-motor-experience-and-conceptual-knowledge-in-action-perception-a-training-study
#12
S A Gerson, M Meyer, S Hunnius, H Bekkering
Prior knowledge affects how we perceive the world and the sensorimotor system actively guides our perception. An ongoing dispute regards the extent to which prior motor knowledge versus conceptual knowledge modulates the observation of others' actions. Research indicates that motor experience increases motor activation during action perception. Other research, however, has shown that conceptual familiarity with actions also modulates motor activation, i.e., increased motor activation during observation of unfamiliar, compared to conceptually familiar, actions...
April 25, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28439232/mapping-the-speech-code-cortical-responses-linking-the-perception-and-production-of-vowels
#13
William L Schuerman, Antje S Meyer, James M McQueen
The acoustic realization of speech is constrained by the physical mechanisms by which it is produced. Yet for speech perception, the degree to which listeners utilize experience derived from speech production has long been debated. In the present study, we examined how sensorimotor adaptation during production may affect perception, and how this relationship may be reflected in early vs. late electrophysiological responses. Participants first performed a baseline speech production task, followed by a vowel categorization task during which EEG responses were recorded...
2017: Frontiers in Human Neuroscience
https://www.readbyqxmd.com/read/28432316/how-visual-experience-impacts-the-internal-and-external-spatial-mapping-of-sensorimotor-functions
#14
Virginie Crollen, Geneviève Albouy, Franco Lepore, Olivier Collignon
Tactile perception and motor production share the use of internally- and externally-defined coordinates. In order to examine how visual experience affects the internal/external coding of space for touch and movement, early blind (EB) and sighted controls (SC) took part in two experiments. In experiment 1, participants were required to perform a Temporal Order Judgment task (TOJ), either with their hands in parallel or crossed over the body midline. Confirming previous demonstration, crossing the hands led to a significant decrement in performance in SC but did not affect EB...
April 21, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28422976/reactivation-or-transformation-motor-memory-consolidation-associated-with-cerebral-activation-time-locked-to-sleep-spindles
#15
Stuart Fogel, Genevieve Albouy, Bradley R King, Ovidiu Lungu, Catherine Vien, Arnaud Bore, Basile Pinsard, Habib Benali, Julie Carrier, Julien Doyon
Motor memory consolidation is thought to depend on sleep-dependent reactivation of brain areas recruited during learning. However, up to this point, there has been no direct evidence to support this assertion in humans, and the physiological processes supporting such reactivation are unknown. Here, simultaneous electroencephalographic and functional magnetic resonance imaging (EEG-fMRI) recordings were conducted during post-learning sleep to directly investigate the spindle-related reactivation of a memory trace formed during motor sequence learning (MSL), and its relationship to overnight enhancement in performance (reflecting consolidation)...
2017: PloS One
https://www.readbyqxmd.com/read/28420977/development-and-training-of-a-neural-controller-for-hind-leg-walking-in-a-dog-robot
#16
Alexander Hunt, Nicholas Szczecinski, Roger Quinn
Animals dynamically adapt to varying terrain and small perturbations with remarkable ease. These adaptations arise from complex interactions between the environment and biomechanical and neural components of the animal's body and nervous system. Research into mammalian locomotion has resulted in several neural and neuro-mechanical models, some of which have been tested in simulation, but few "synthetic nervous systems" have been implemented in physical hardware models of animal systems. One reason is that the implementation into a physical system is not straightforward...
2017: Frontiers in Neurorobotics
https://www.readbyqxmd.com/read/28420973/no-overt-effects-of-a-6-week-exergame-training-on-sensorimotor-and-cognitive-function-in-older-adults-a-preliminary-investigation
#17
Madeleine Ordnung, Maike Hoff, Elisabeth Kaminski, Arno Villringer, Patrick Ragert
Several studies investigating the relationship between physical activity and cognition showed that exercise interventions might have beneficial effects on working memory, executive functions as well as motor fitness in old adults. Recently, movement based video games (exergames) have been introduced to have the capability to improve cognitive function in older adults. Healthy aging is associated with a loss of cognitive, as well as sensorimotor functions. During exergaming, participants are required to perform physical activities while being simultaneously surrounded by a cognitively challenging environment...
2017: Frontiers in Human Neuroscience
https://www.readbyqxmd.com/read/28409511/multimodal-assessment-of-sensorimotor-shoulder-function-in-patients-with-untreated-anterior-shoulder-instability-and-asymptomatic-handball-players
#18
Guillaume Mornieux, Anja Hirschmüller, Albert Gollhofer, Norbert P Südkamp, Dirk Maier
BACKGROUND: Functional evaluation of sensorimotor function of the shoulder joint is important for guidance of sports-specific training, prevention and rehabilitation of shoulder instability. Such assessment should be multimodal and comprise all qualities of sensorimotor shoulder function. This study evaluates feasibility of such multimodal assessment of glenohumeral sensorimotor function in patients with shoulder instability and handball players. METHODS: Nine patients with untreated anterior instability of their dominant shoulder and 15 asymptomatic recreational handball players performed proprioceptive joint position sense and dynamic stabilisation evaluations on an isokinetic device, as well as a functional throwing performance task...
April 13, 2017: Journal of Sports Medicine and Physical Fitness
https://www.readbyqxmd.com/read/28409112/plasticity-of-premotor-cortico-muscular-coherence-in-severely-impaired-stroke-patients-with-hand-paralysis
#19
Paolo Belardinelli, Leonard Laer, Erick Ortiz, Christoph Braun, Alireza Gharabaghi
Motor recovery in severely impaired stroke patients is often very limited. To refine therapeutic interventions for regaining motor control in this patient group, the functionally relevant mechanisms of neuronal plasticity need to be detected. Cortico-muscular coherence (CMC) may provide physiological and topographic insights to achieve this goal. Synchronizing limb movements to motor-related brain activation is hypothesized to reestablish cortico-motor control indexed by CMC. In the present study, right-handed, chronic stroke patients with right-hemispheric lesions and left hand paralysis participated in a four-week training for their left upper extremity...
2017: NeuroImage: Clinical
https://www.readbyqxmd.com/read/28408414/posterior-parietal-cortex-guides-visual-decisions-in-rats
#20
Angela M Licata, Matthew T Kaufman, David Raposo, Michael B Ryan, John P Sheppard, Anne K Churchland
Neurons in putative decision-making structures can reflect both sensory and decision signals, making their causal role in decisions unclear. Here, we tested whether rat posterior parietal cortex (PPC) is causal for processing visual sensory signals or instead for accumulating evidence for decision alternatives. We disrupted PPC activity optogenetically during decision making and compared effects on decisions guided by auditory versus visual evidence. Deficits were largely restricted to visual decisions. To further test for visual dominance in PPC, we evaluated electrophysiological responses after individual sensory events and observed much larger response modulation after visual stimuli than auditory stimuli...
May 10, 2017: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
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