keyword
https://read.qxmd.com/read/35601763/phenotypic-changes-of-trichinella-spiralis-treated-by-commiphora-molmol-lepidium-sativum-and-albendazole-in-vitro-study
#21
JOURNAL ARTICLE
G L Abuelenain, Z H Fahmy, A M Elshennawy, E H A Selim, M Elhakeem, K M A Hassanein, S M Awad
Trichinellosis is a nematode-causing disease distinguished by its continuous transmission in the carnivores and omnivores. Despite effective eradication of the enteral forms, conventional drugs fail to eliminate the migrating and muscle ones. Over the past years, researchers intensified the work on herbal medicines as alternatives or aids to albendazole, the reference drug. This research hypothesizes that the therapeutic agent absorption route could be an evidence-based carrier molecule or auxiliary drug to albendazole...
March 2022: Helminthologia
https://read.qxmd.com/read/35061249/ultrafiltration-for-acute-heart-failure
#22
REVIEW
Mehul Srivastava, Nicholas Harrison, Ana Francisca Sma Caetano, Audrey R Tan, Mandy Law
BACKGROUND: Pharmacotherapies such as loop diuretics are the cornerstone treatment for acute heart failure (AHF), but resistance and poor response can occur. Ultrafiltration (UF) is an alternative therapy to reduce congestion, however its benefits, efficacy and safety are unclear. OBJECTIVES: To assess the effects of UF compared to diuretic therapy on clinical outcomes such as mortality and rehospitalisation rates. SEARCH METHODS: We undertook a systematic search in June 2021 of the following databases: CENTRAL, MEDLINE, Embase, Web of Science CPCI-S and ClinicalTrials...
January 21, 2022: Cochrane Database of Systematic Reviews
https://read.qxmd.com/read/34967579/effects-of-complementary-and-alternative-medicine-on-chemotherapy-delivery-in-thai-patients
#23
JOURNAL ARTICLE
Chawanya Rabiltossaporn, Ploytuangporn Wongchanapai, Nattaya Poovoravan, Piyada Sitthideatphaiboon, Virote Sriuranpong, Suebpong Tanasanvimon
BACKGROUND: Complementary and Alternative Medicine (CAM) is widely used among cancer patients worldwide. This prospective observational study aimed to show the effect of CAM use on chemotherapy delivery in Thai patients. METHODS: During March 2014 to February 2015, the patients with breast, lung or colorectal cancer receiving first cycle chemotherapy at King Chulalongkorn Memorial Hospital were enrolled. The correlation between CAM using and chemotherapy schedule delay and dose reduction, dose intensity, quality of life and adverse event rates were analyzed...
December 1, 2021: Asian Pacific Journal of Cancer Prevention: APJCP
https://read.qxmd.com/read/34858507/dance-movement-therapy-as-an-intervention-in-breast-cancer-patients-a-systematic-review
#24
REVIEW
Natalja Fatkulina, Vaiva Hendrixson, Alona Rauckiene-Michealsson, Justina Kievisiene, Arturas Razbadauskas, Cesar Agostinis Sobrinho
AIM: In this paper, we systematically review the evidence looking at the effect of dance/movement therapy (DMT) and mental health outcomes and quality of life in breast cancer patients. METHOD: The literature search was done with the databases PubMed (MEDLINE), EBSCO, and Cochrane Central by using the following search words: "dancing/dance/movement therapy," "breast cancer/neoplasms/carcinoma/tumour" or "mammary cancer," "mental health," and "quality of life." Ninety-four articles were found...
2021: Evidence-based Complementary and Alternative Medicine: ECAM
https://read.qxmd.com/read/34502166/integrated-medicine-for-chemotherapy-induced-peripheral-neuropathy
#25
REVIEW
Chih-Hung Tsai, Yuan-Ho Lin, Yung-Sheng Li, Trung-Loc Ho, Le Huynh Hoai Thuong, Yu-Huei Liu
Chemotherapy-induced peripheral neuropathy (CIPN) is a common side effect of typical chemotherapeutics among cancer survivors. Despite the recent progress, the effective prevention and treatment strategies for CIPN remain limited. Better understanding of the pathogenesis of CIPN may provide new niches for developing a new ideal therapeutic strategy. This review summarizes the current understanding of CIPN and current recommendations along with completed/active clinical trials and aims to foster translational research to improve the development of effective strategies for managing CIPN...
August 26, 2021: International Journal of Molecular Sciences
https://read.qxmd.com/read/34453567/cannabis-use-among-danish-patients-with-cancer-a-cross-sectional-survey-of-sociodemographic-traits-quality-of-life-and-patient-experiences
#26
JOURNAL ARTICLE
Sebastian W Nielsen, Christina H Ruhlmann, Lise Eckhoff, Dorthe Brønnum, Jørn Herrstedt, Susanne O Dalton
PURPOSE: Patients with cancer are using cannabis for self-treatment. The reasons, experienced effects, and prevalence of use are unknown in the European general oncological population. METHODS: Adult patients with cancer attending outpatient oncology clinics were invited to participate in a cross-sectional survey. The questionnaire consisted of sociodemographic questions, validated scales on quality of life, neuropathy, anxiety and depression as well as questions regarding use of cannabis...
February 2022: Supportive Care in Cancer
https://read.qxmd.com/read/34262950/correlation-between-cha-2-ds-2-vasc-score-and-left-atrial-size-in-patients-with-atrial-fibrillation-a-more-than-15-year-prospective-follow-up-study
#27
JOURNAL ARTICLE
Chin-Feng Tsai, Pang-Shuo Huang, Jien-Jiun Chen, Sheng-Nan Chang, Fu-Chun Chiu, Ting-Tse Lin, Ling-Ping Lai, Juey-Jen Hwang, Chia-Ti Tsai
Background: Left atrial (LA) size represents atrial fibrillation (AF) burden and has been shown to be a predictor for AF stroke. The CHA2 DS2 -VASc score is also a well-established predictor of AF stroke. It is unknown to cardiologists whether these two risk scores are correlated, whether both are independent prognostic predictors and complimentary to each other, or whether one of them is a major determinant of stroke risk for AF patients. Method: A total of 708 patients from the National Taiwan University Atrial Fibrillation Registry were longitudinally followed up for more than 15 years...
2021: Frontiers in Cardiovascular Medicine
https://read.qxmd.com/read/34197457/optimizing-the-microscopic-agglutination-test-mat-panel-for-the-diagnosis-of-leptospirosis-in-a-low-resource-hyper-endemic-setting-with-varied-microgeographic-variation-in-reactivity
#28
JOURNAL ARTICLE
Dinesha Jayasundara, Chandika Gamage, Indika Senavirathna, Janith Warnasekara, Michael A Matthias, Joseph M Vinetz, Suneth Agampodi
The microscopic agglutination test (MAT) is the standard serological reference test for the diagnosis of leptospirosis, despite being a technically demanding and laborious procedure. The use of a locally optimised MAT panel is considered essential for proper performance and interpretation of results. This paper describes the procedure of selecting such an optimised panel for Sri Lanka, a country hyper-endemic for leptospirosis. MAT was performed using 24 strains on 1132 serum samples collected from patients presenting with acute undifferentiated fever...
July 2021: PLoS Neglected Tropical Diseases
https://read.qxmd.com/read/34165405/targeting-chikungunya-virus-entry-alternatives-for-new-inhibitors-in-drug-discovery
#29
JOURNAL ARTICLE
Leandro Rocha Silva, Érica Erlanny da Silva Rodrigues, Jamile Taniele-Silva, Letícia Anderson, João Xavier de Araújo-Júnior, Ênio José Bassi, Edeildo F da Silva-Júnior
Chikungunya virus (CHIKV) is an Alphavirus (Togaviridae) responsible for Chikungunya fever (CHIKF) that is mainly characterized by a severe polyarthralgia, in which it is transmitted by the bite of infected Aedes aegypti and Ae. albopictus mosquitoes. Nowadays, there no licensed vaccines or approved drugs to specifically treat this viral disease. Structural viral proteins participate in key steps of its replication cycle, such as viral entry, membrane fusion, nucleocapsid assembly, and virus budding. In this context, envelope E3-E2-E1 glycoproteins complex could be targeted for designing new drug candidates...
June 23, 2021: Current Medicinal Chemistry
https://read.qxmd.com/read/34041140/coronavirus-disease-2019-and-the-natural-agents-is-there-a-role-for-the-primary-care
#30
REVIEW
Manal O Alharthi, Raghad A Alasmari, Rahaf I Almatani, Rehab M Alharthi, Suha A Aljumaiei, Bashayr A Alkuhayli, Ahmed M Kabel
Coronavirus disease 2019 (COVID-19) is a newly discovered RNA virus that belongs to corona virus group. It leads to an infectious state manifested as fever, loss of smell and taste sensations, cough, myalgia, fatigue and headache. The condition may become more serious as difficulty in breathing, chest pain and even death. Until successful vaccine is developed, complimentary and herbal medicine can be used as alternative prevention measure against COVID-19 in high-risk populations. This is because the none of the traditional agents used in the treatment protocols had proven effective results...
March 2021: Journal of Family Medicine and Primary Care
https://read.qxmd.com/read/34041071/evaluation-of-prescription-practices-in-rheumatoid-arthritis-at-the-rheumatology-clinic-in-a-tertiary-care-teaching-hospital-in-uttarakhand-a-cross-sectional-study
#31
JOURNAL ARTICLE
Gauri Mittal, Manisha Bisht, Venkatesh S Pai, Shailendra S Handu
OBJECTIVE: This study was aimed to analyze the prescription pattern of disease modifying anti-rheumatic drug (DMARD) therapy in patients with rheumatoid arthritis (RA) in a tertiary care teaching hospital in Uttarakhand, India. METHODOLOGY: This cross-sectional study was conducted in 150 RA patients who were given DMARD therapy. Patient's demographic details, drugs prescribed with their dosage and administration routes and the usage of complementary and alternative medicine (CAM) therapy were recorded to study the prescription pattern...
February 2021: Journal of Family Medicine and Primary Care
https://read.qxmd.com/read/33994711/the-indian-network-of-drug-induced-liver-injury-etiology-clinical-features-outcome-and-prognostic-markers-in-1288-patients
#32
JOURNAL ARTICLE
Harshad Devarbhavi, Tarun Joseph, Nanjegowda Sunil Kumar, Chetan Rathi, Varghese Thomas, Shivaram Prasad Singh, Prabha Sawant, Ashish Goel, Chundamannil E Eapen, Prakash Rai, Anil Arora, Venkatakrishnan Leelakrishnan, Gayathri Gopalakrishnan, Vishnu Vardhan Reddy, Rajvir Singh, Bhabadev Goswami, Jayanthi Venkataraman, Girisha Balaraju, Mallikarjun Patil, Rakesh Patel, Sunil Taneja, Abraham Koshy, Padaki Nagaraja Rao, Shiv Kumar Sarin, Pravin Rathi, Radhakrishna Dhiman, Ajay K Duseja, Joy Vargese, Ajay Kumar Jain, Manav Wadhawan, Piyush Ranjan, Dheeraj Karanth, Panchapakesan Ganesh, Sandeep Nijhawan, Gopal Krishna Dhali, Channagiri K Adarsh, Ajay Jhaveri, Aabha Nagral, Prasanna Rao, Shalimar
BACKGROUND: Etiology of and outcomes following idiosyncratic drug-induced liver injury (DILI) vary geographically. We conducted a prospective study of DILI in India, from 2013 to 2018 and summarize the causes, clinical features, outcomes and predictors of mortality. METHODS: We enrolled patients with DILI using international DILI expert working group criteria and Roussel Uclaf causality assessment method. Follow-up was up to 3 months from onset of DILI or until death...
May 2021: Journal of Clinical and Experimental Hepatology
https://read.qxmd.com/read/33926448/a-systematic-review-and-meta-analysis-of-the-role-of-sugar-free-chewing-gum-on-streptococcus-mutans
#33
JOURNAL ARTICLE
Melanie Nasseripour, Jonathon Timothy Newton, Fiona Warburton, Oluwatunmise Awojobi, Sonya Di Giorgio, Jennifer Elizabeth Gallagher, Avijit Banerjee
BACKGROUND: Preventive strategies targeting Streptococcus mutans may be effective in reducing the global burden of caries. The aim of the current systematic review of published literature was to determine the difference in level of Streptococcus mutans in adults and children who chew sugar-free gum (SFG), compared with those who did not chew gum, who chewed a control gum or received alternatives such as probiotics or fluoride varnish. METHODS: Systematic review (PROSPERO registration No...
April 29, 2021: BMC Oral Health
https://read.qxmd.com/read/33666218/molecular-mechanisms-of-transcription-factor-mediated-cell-reprogramming-conversion-of-liver-to-pancreas
#34
REVIEW
Sebastian L Wild, David Tosh
Transdifferentiation is a type of cellular reprogramming involving the conversion of one differentiated cell type to another. This remarkable phenomenon holds enormous promise for the field of regenerative medicine. Over the last 20 years techniques used to reprogram cells to alternative identities have advanced dramatically. Cellular identity is determined by the transcriptional profile which comprises the subset of mRNAs, and therefore proteins, being expressed by a cell at a given point in time. A better understanding of the levers governing transcription factor activity benefits our ability to generate therapeutic cell types at will...
April 30, 2021: Biochemical Society Transactions
https://read.qxmd.com/read/33585075/complementary-and-alternative-cam-treatment-options-for-women-with-pelvic-pain
#35
JOURNAL ARTICLE
Malathy Srinivasan, Joseph E Torres, Donald McGeary, Ameet S Nagpal
PURPOSE OF REVIEW: I.To provide an overview of the current complementary and alternative (CAM) treatment options for women with chronic pelvic pain (CPP). RECENT FINDINGS: II.Recent studies on chronic pain at cellular, molecular and network level and their interaction with the immune system has unfolded several mechanisms for pain making it promising to explore the alternative paradigm to manage the incredibly complex chronic pelvic pain condition where multifactorial etiology often limits successful outcomes...
September 2020: Current Physical Medicine and Rehabilitation Reports
https://read.qxmd.com/read/33549281/highs-lows-and-health-hazards-of-herbology-a-review-of-herbal-medications-with-psychotropic-effects
#36
REVIEW
Shannon L Smith-Stephens
Mental health disorders, including depression, anxiety, and insomnia, are leading causes of hospitalization and disability for young and middle-aged adults. Approximately one-half of Americans will be diagnosed with a mental illness during their lifetime. Plants and roots have been used as medicinal agents since the beginning of recorded time. Complementary and alternative medicine or complementary integrative medicine use has been increasing throughout most socioeconomic classes, cultures, and age categories...
March 2021: Nursing Clinics of North America
https://read.qxmd.com/read/33509328/complementary-medicine-who-are-we-to-judge
#37
JOURNAL ARTICLE
Chris Alderman
Dr. Alderman implores pharmacists to approach the prevalence of patients taking complimentary and using alternative therapies with logic over judgement, and, to see that an opportunity exists for the profession to be brokers of sensible, precautionary information that may protect their patients from serious unintended harm.
February 1, 2021: Senior Care Pharmacist
https://read.qxmd.com/read/33321899/indian-medicinal-herbs-and-formulations-for-alzheimer-s-disease-from-traditional-knowledge-to-scientific-assessment
#38
REVIEW
Jogender Mehla, Pooja Gupta, Monika Pahuja, Deepti Diwan, Diksha Diksha
Cognitive impairment, associated with ageing, stress, hypertension and various neurodegenerative disorders including Parkinson's disease and epilepsy, is a major health issue. The present review focuses on Alzheimer's disease (AD), since it is the most important cause of cognitive impairment. It is characterized by progressive memory loss, language deficits, depression, agitation, mood disturbances and psychosis. Although the hallmarks of AD are cholinergic dysfunction, β-amyloid plaques and neurofibrillary tangle formation, it is also associated with derangement of other neurotransmitters, elevated levels of advanced glycation end products, oxidative damage, neuroinflammation, genetic and environmental factors...
December 10, 2020: Brain Sciences
https://read.qxmd.com/read/33162692/use-of-complementary-and-alternative-medicine-cam-and-home-remedies-by-covid-19-patients-a-telephonic-survey
#39
JOURNAL ARTICLE
Jaykaran Charan, Pankaj Bhardwaj, Siddhartha Dutta, Rimplejeet Kaur, Sunil Kumar Bist, Mohan Dan Detha, Tanuj Kanchan, Dharamveer Yadav, Prasenjit Mitra, Praveen Sharma
COVID-19 is caused by a novel coronavirus which was first reported in Wuhan city, China. The pandemic has led to considerable mortality globally. India, at present has the second largest burden of COVID-19 cases globally. Clinical trials with new interventions, including new vaccine candidates are being explored in the scientific world. Countries like China and India, with a rich history of traditional medicine, are exploring the effectiveness of traditional medicines to treat COVID-19. This study included 725 patients from an Isolation center, of which 230 (31...
October 31, 2020: Indian Journal of Clinical Biochemistry: IJCB
https://read.qxmd.com/read/32778989/gender-differences-in-beliefs-and-attitudes-towards-complementary-and-alternative-medicine-use-among-a-non-urban-malaysian-population
#40
JOURNAL ARTICLE
Yee Ern Esther Teow, Amuthaganesh Mathialagan, Siew Ching Ng, Hui Yew Olivia Tee, Warren Thomas
The choice to take-up specific complimentary and alternative medicine (CAM) modalities is influenced by many factors including cultural background, experience and peer-participation. In this study we investigated the beliefs and attitudes that contributed to CAM choices in a non-urban Malaysian population (N = 700). We found significant differences in the beliefs held by men and women in this population. Specifically, women believed more strongly than men that CAM providers offered healthy lifestyle advice (p = 0...
August 11, 2020: Journal of Community Health
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