keyword
https://read.qxmd.com/read/38376942/the-evolutionary-phylodynamics-of-human-parechovirus-a-type-3-reveal-multiple-recombination-events-in-south-korea
#21
JOURNAL ARTICLE
Thoi C Truong, Heekuk Park, Jong-Hwa Kim, Van Trung Tran, Wonyong Kim
Human parechovirus A (HPeV-A) is a causative agent of respiratory and gastrointestinal illnesses, acute flaccid paralysis encephalitis, meningitis, and neonatal sepsis. To clarify the characteristics of HPeV-A infection in children, 391 fecal specimens were collected from January 2014 to October 2015 from patients with acute gastroenteritis in Seoul, South Korea. Of these, 221/391 (56.5%) HPeV-A positive samples were found in children less than 2 years old. Three HPeV-A genotypes HPeV-A1 (117/221; 52.94%), HPeV-A3 (100/221; 45...
February 2024: Journal of Medical Virology
https://read.qxmd.com/read/38357183/the-road-to-a-polio-free-uganda-contribution-of-the-expanded-program-on-immunization-laboratory-epi-lab-at-uganda-virus-research-institute
#22
JOURNAL ARTICLE
Mary B Nanteza, Phionah Tushabe, Henry Bukenya, Prossy Namuwulya, Theopista Kabaliisa, Molly Birungi, Mayi Tibanagwa, Immaculate Ampeire, Proscovia Kakooza, Edson Katushabe, Josephine Bwogi, Barnabas Bakamutumaho, Miriam Nanyunja, Charles R Byabamazima
BACKGROUND: The control of poliomyelitis in Uganda dates back as far as 1950 and acute flaccid paralysis (AFP) surveillance has since been used as a criterion for identifying wild polioviruses. Poliovirus isolation was initially pursued through collaborative research however, in 1993, the Expanded Program on Immunization Laboratory (EPI-LAB) was established as a member of the Global Poliovirus Laboratory Network (GPLN) and spearheaded this activity at Uganda Virus Research Institute. OBJECTIVES: The aim of this report is to document the progress and impact of the EPI-LAB on poliovirus eradication in Uganda...
September 2023: African Health Sciences
https://read.qxmd.com/read/38352138/guillain-barr%C3%A3-syndrome-post-sars-cov-2-vaccine-a-systematic-review-and-data-analysis-on-its-clinical-laboratory-electrophysiological-and-radiological-features
#23
REVIEW
Kawther Hadhiah, Ali Alhashim, Hassan A Al-Dandan, Eman Alhassan, Abdulaziz M Alqarni, Abdullah Adil A Memish, Majed Alabdali
INTRODUCTION: Guillain-Barré syndrome (GBS) is a rare disease that affects almost 0.8-1.9 cases per 100,000 people worldwide every year. This is the most prevalent cause of subacute flaccid paralyzing illness today. It is a subacute inflammatory demyelinating polyradiculoneuropathy; the typical scenario involves ascending symmetrical flaccid paralysis, but in some circumstances, sensory, autonomic, and cranial neuropathy may also be involved. Several vaccines have been found to have complications since the previous century...
2024: Frontiers in Neurology
https://read.qxmd.com/read/38344530/effectiveness-of-physiotherapy-intervention-in-guillain-barre-syndrome-a-case-report
#24
Ishwari Gawande, Aditi Akhuj, Snehal Samal
Guillain-Barre syndrome (GBS) is described by a wide range of motor impairment, flaccidity, hyporeflexia, and progressive and ascending flaccid paralysis. Group B Streptococcus , also known as Streptococcus agalactia and Campylobacter jejuni , are Gram-positive bacteria also known as the leading cause of GBS; its variants are acute motor axonal neuropathy (AMAN), acute motor and sensory axonal neuropathy (AMSAN), acute inflammatory demyelinating neuropathy (AIDP), and Miller-Fisher syndrome (MFS)...
January 2024: Curēus
https://read.qxmd.com/read/38344355/conus-medullaris-neuroschistosomiasis-mimicking-guillain-barre-syndrome-a-case-of-delayed-diagnosis-leading-to-permanent-neurological-damage
#25
Nabil Aljuma'ai, Saif A Ghabisha, Faisal Ahmed, Taha Al-Mwald, Abdullatif Almohtadi, Mohamed Badheeb
KEY CLINICAL MESSAGE: In the evaluation of acute flaccid paralysis, particularly in pediatric populations within endemic areas for schistosomiasis infection, clinicians must maintain a high index of suspicion for neuroschistosomiasis. Prompt identification is imperative to mitigate the risk of irreversible neurological sequelae. ABSTRACT: Spinal cord involvement in neuroschistosomiasis (NS) is considerably rare, with even fewer reported cases affecting the conus medullaris in children...
February 2024: Clinical Case Reports
https://read.qxmd.com/read/38343664/re-emergence-of-polio-in-pakistan-can-the-nation-achieve-the-wpv1-eradication-goal
#26
JOURNAL ARTICLE
Aqib Faizan, Tooba Rehman, Sanila Mughal
BACKGROUND AND AIMS: Poliomyelitis is an acute neurologic condition that causes muscle weakness, permanent flaccid paralysis, and even death. The world has seen a drastic fall in the number of poliovirus cases owing to effective immunization programs and preventive measures. Pakistan and Afghanistan still remain the two endemic countries for poliovirus, particularly, the WPV1 strain. Global Polio Eradication Initiative (GPEI) has set a target to eradicate all WPV1 cases by the end of 2023...
February 2024: Health Science Reports
https://read.qxmd.com/read/38337090/analgesic-effect-of-neuromodulation-using-the-at-04-portable-magnetic-field-generating-device-in-a-patient-with-neuropathic-pain-a-case-report
#27
JOURNAL ARTICLE
Atsushi Sawada, Michiaki Yamakage
BACKGROUND: Neuromodulation by magnetic field through the AT-04 (ait® (AT-04); Peace of Mind Co., Ltd., Kumamoto, Japan) has improved allodynia in neuropathic pain model rats. This report focuses on neuromodulation through magnetic field exposure using the AT-04 that provided an analgesic effect in a patient with neuropathic pain. CASE PRESENTATION: A 47-year-old man presented with flaccid paralysis and extensive neuropathic pain and scored 7 on the 11-point Numerical Rating Scale (NRS) for his left upper limb...
February 10, 2024: JA Clinical Reports
https://read.qxmd.com/read/38332009/genotype-f-of-echovirus-25-with-multiple-recombination-pattern-have-been-persistently-and-extensively-circulating-in-chinese-mainland
#28
JOURNAL ARTICLE
Xiaoyi Wang, Jianping Cun, Shikang Li, Yong Shi, Yingying Liu, Haiyan Wei, Yong Zhang, Ruyi Cong, Tingting Yang, Wenhui Wang, Jinbo Xiao, Yang Song, Dongmei Yan, Qian Yang, Qiang Sun, Tianjiao Ji
Echovirus 25 (E25), a member of the Enterovirus B (EV-B) species, can cause aseptic meningitis (AM), viral meningitis (VM), and acute flaccid paralysis (AFP). However, systematic studies on the molecular epidemiology of E25, especially those concerning its evolution and recombination, are lacking. In this study, 18 strains of E25, isolated from seven provinces of China between 2009 and 2018, were collected based on the Chinese hand, foot, and mouth disease (HFMD) surveillance network, and 95 sequences downloaded from GenBank were also screened...
February 8, 2024: Scientific Reports
https://read.qxmd.com/read/38328499/stem-cell-transplant-in-immune-deficiency-associated-vaccine-derived-poliovirus
#29
JOURNAL ARTICLE
Heena Ranchod, Wayne Howard, Adele Roux, Walda van Zyl, Pieter Ekermans, Sylvia van den Berg, Lerato Seakamela, Koketso Makua, Mukhlid Yousif, Rosinah Sibiya, Heleen Du Plessis, Emmanuel Phalane, Kerrigan McCarthy, Shelina Moonsamy, David Reynders, Jeffrey Hincks, Melinda S Suchard, Nicolette M du Plessis
Patients with severe primary immunodeficiency are at risk for complications from live-attenuated vaccines. Here, we report a case of a vaccine-associated paralytic polio and Bacille Calmette-Guérin disease in a 6-month-old girl with severe combined immunodeficiency resulting from homozygous recombinant activating gene 1 deficiency. The patient was successfully treated with intravenous immunoglobulins and oral pocapavir for poliovirus, and antimycobacterial therapy for regional Bacille Calmette-Guérin disease, allowing stem cell transplant...
February 2024: Open Forum Infectious Diseases
https://read.qxmd.com/read/38316500/apparent-tick-paralysis-by-otobius-megnini-in-a-cat
#30
Ian K Daniel, Rafael A N Ramos, Joe L Luksovsky, Mario Arredondo Galindo, Meriam N Saleh, Guilherme G Verocai
In this study, we report a rare case of tick paralysis in a cat induced by Otobius megnini infestation. An 11-month-old female cat was admitted to a private veterinary clinic in Luling Texas, USA presenting with depression, tachycardia, and flaccid paralysis of the entire body. The four recovered ticks were morphologically and molecularly identified as O. megnini nymphs. Following initial tick removal and treatment with 0.1% milbemycin oxime in the ear canal on the first day of hospitalization, and additional tick removal and topical selamectin treatment on the second day of hospitalization the animal gradually improved...
February 2024: Veterinary Parasitology (Amsterdam)
https://read.qxmd.com/read/38300829/surveillance-for-acute-flaccid-myelitis-united-states-2018-2022
#31
JOURNAL ARTICLE
Erin R Whitehouse, Adriana Lopez, Randall English, Halle Getachew, Terry Fei Fan Ng, Brian Emery, Shannon Rogers, Sarah Kidd
Acute flaccid myelitis (AFM) is a serious neurologic condition primarily affecting children; AFM can cause acute respiratory failure and permanent paralysis. AFM is a rare but known complication of various viral infections, particularly those of enteroviruses (EVs). Increases in AFM cases during 2014, 2016, and 2018 were associated with EV-D68 infection. This report examines trends in confirmed AFM cases during 2018-2022 and patients' clinical and laboratory characteristics. The number of AFM cases was low during 2019-2022 (28-47 cases per year); the number of cases remained low in 2022 despite evidence of increased EV-D68 circulation in the United States...
February 1, 2024: MMWR. Morbidity and Mortality Weekly Report
https://read.qxmd.com/read/38296775/acute-ascending-flaccid-paralysis-in-a-healthy-16-year-old
#32
JOURNAL ARTICLE
Michael P Penfold, Keith Starnes, Margarita Corredor
No abstract text is available yet for this article.
February 1, 2024: Pediatrics in Review
https://read.qxmd.com/read/38270731/only-anti-gm4-antibody-positivity-in-a-chinese-girl-with-overlapping-mfs-gbs-a-case-report
#33
JOURNAL ARTICLE
Jing Chen, Maoqiang Tian, XiaoMei Shu
BACKGROUND: Guillain-Barré syndrome (GBS), as the most common cause of acute flaccid paralysis worldwide, is considered a part of a clinical spectrum in which discrete, complete, or incomplete forms of GBS and overlapping syndromes lie on the basis of their clinical features. The term overlapping Miller Fisher syndrome (MFS)/GBS is used when patients with MFS also suffer from progressive motor weakness of the limbs. Anti-ganglioside GQ1b has been specifically associated with MFS and ophthalmoplegia...
January 25, 2024: Neurological Sciences
https://read.qxmd.com/read/38262228/acute-flaccid-paralysis-seizures-and-encephalopathy-in-a-pediatric-patient-with-influenza-a-and-coronavirus-disease-2019-infection
#34
JOURNAL ARTICLE
Natalie Sloof, Christopher Donald Hue, Craig Campbell, Michelle A Barton, Maryam Nabavi Nouri
No abstract text is available yet for this article.
March 2024: Pediatric Neurology
https://read.qxmd.com/read/38259063/human-b-cells-and-dendritic-cells-are-susceptible-and-permissive-to-enterovirus-d68-infection
#35
JOURNAL ARTICLE
Brigitta M Laksono, Syriam Sooksawasdi Na Ayudhya, Muriel Aguilar-Bretones, Carmen W E Embregts, Gijsbert P van Nierop, Debby van Riel
Enterovirus D68 (EV-D68) is predominantly associated with mild respiratory infections, but can also cause severe respiratory disease and extra-respiratory complications, including acute flaccid myelitis. Systemic dissemination of EV-D68 is crucial for the development of extra-respiratory diseases, but it is currently unclear how EV-D68 spreads systemically (viremia). We hypothesize that immune cells contribute to the systemic dissemination of EV-D68, as this is a mechanism commonly used by other enteroviruses...
January 23, 2024: MSphere
https://read.qxmd.com/read/38257835/non-polio-enteroviruses-isolated-by-acute-flaccid-paralysis-surveillance-laboratories-in-the-russian-federation-in-1998-2021-distinct-epidemiological-features-of-types
#36
JOURNAL ARTICLE
Olga E Ivanova, Tatiana P Eremeeva, Nadezhda S Morozova, Yulia M Mikhailova, Liubov I Kozlovskaya, Olga Y Baikova, Armen K Shakaryan, Alexandr Y Krasota, Ekaterina A Korotkova, Elizaveta V Yakovchuk, Elena Y Shustova, Alexander N Lukashev
More than 100 types of non-polio enteroviruses (NPEVs) are ubiquitous in the human population and cause a variety of symptoms ranging from very mild to meningitis and acute flaccid paralysis (AFP). Much of the information regarding diverse pathogenic properties of NPEVs comes from the surveillance of poliovirus, which also yields NPEV. The analysis of 265 NPEV isolations from 10,433 AFP cases over 24 years of surveillance and more than 2500 NPEV findings in patients without severe neurological lesions suggests that types EV-A71, E13, and E25 were significantly associated with AFP...
January 18, 2024: Viruses
https://read.qxmd.com/read/38246190/effectiveness-of-poliovirus-vaccines-against-circulating-vaccine-derived-type-2-poliomyelitis-in-nigeria-between-2017-and-2022-a-case-control-study
#37
JOURNAL ARTICLE
Laura V Cooper, Tesfaye B Erbeto, Abba A Danzomo, Hamisu W Abdullahi, Kofi Boateng, Usman S Adamu, Faisal Shuaib, Ndoutabe Modjirom, Elizabeth J Gray, Ananda S Bandyopadhyay, Simona Zipursky, Samuel O Okiror, Nicholas C Grassly, Isobel M Blake
BACKGROUND: Between 2018 and 2022, Nigeria experienced continuous transmission of circulating vaccine-derived type 2 poliovirus (cVDPV2), with 526 cases of cVDPV2 poliomyelitis detected in total and approximately 180 million doses of monovalent type 2 oral poliovirus vaccine (mOPV2) and 450 million doses of novel type 2 oral poliovirus vaccine (nOPV2) delivered in outbreak response campaigns. Inactivated poliovirus vaccine (IPV) was introduced into routine immunisation in 2015, with a second dose added in 2021...
January 18, 2024: Lancet Infectious Diseases
https://read.qxmd.com/read/38243167/effective-partnership-and-in-country-resource-mobilization-in-sudan-for-cvdpv2-outbreak-response-amid-multiple-emergencies-in-2020-2021
#38
JOURNAL ARTICLE
Mohammed Taufiq Mashal, Dalya Eltayeb, Ariel Higgins-Steele, Ismael Suleiman El Sheikh, Ni'ma Saeed Abid, Hemant Shukla, Leonard Machado, Hamid Jafari
BACKGROUND: During 2020 and immediately prior to the COVID-19 pandemic, Sudan was experiencing multiple emergencies including violence, seasonal flooding, and vector-borne disease outbreaks. After more than ten years since its last case of wild poliovirus, Sudan declared a circulating vaccine-derived poliovirus type 2 (cVDPV2) outbreak on 9 August 2020. METHODS: cVDPV2 outbreak response data and programme documents of the Federal Ministry of Health and WHO were reviewed...
January 19, 2024: BMC Public Health
https://read.qxmd.com/read/38240287/tribbles-pseudokinase-3-promotes-enterovirus-a71-infection-via-dual-mechanisms
#39
JOURNAL ARTICLE
Huiqiang Wang, Ke Li, Boming Cui, Haiyan Yan, Shuo Wu, Kun Wang, Ge Yang, Jiandong Jiang, Yuhuan Li
Enterovirus A71 (EV-A71) is the main pathogen causing hand, foot and mouth disease (HFMD) in children and occasionally associated with neurological diseases such as aseptic meningitis, brainstem encephalitis (BE) and acute flaccid paralysis. We report here that cellular pseudokinase tribbles 3 (TRIB3) facilitates the infection of EV-A71 via dual mechanisms. In one hand, TRIB3 maintains the metabolic stability of scavenger receptor class B member 2 (SCARB2), the bona fide receptor of EV-A71, to enhance the infectious entry and spreading of the virus...
December 2024: Emerging Microbes & Infections
https://read.qxmd.com/read/38233293/detection-of-enterovirus-d68-among-children-with-severe-acute-respiratory-infection-in-myanmar
#40
JOURNAL ARTICLE
Tatsuki Ikuse, Yuta Aizawa, Ryotaro Kachikawa, Kazuhiro Kamata, Hidekazu Osada, Su Mon Kyaw Win, Lasham Di Ja, Nay Chi Win, Khin Nyo Thein, Aye Thida, Aye Tun, Ai Ito, Yadanar Kyaw, Htay Htay Tin, Yugo Shobugawa, Hisami Watanabe, Reiko Saito, Akihiko Saitoh
BACKGROUND: Enterovirus D68 (EV-D68) is an important reemerging pathogen that causes severe acute respiratory infection and acute flaccid paralysis, mainly in children. Since 2014, EV-D68 outbreaks have been reported in the United States, Europe, and east Asia; however, no outbreaks have been reported in southeast Asian countries, including Myanmar, during the previous 10 years. METHODS: EV-D68 was detected in nasopharyngeal swabs from children with acute lower respiratory infections in Myanmar...
January 5, 2024: Journal of Microbiology Immunology and Infection
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