keyword
https://read.qxmd.com/read/38408496/children-s-empathy-moderates-the-association-between-perceived-interparental-conflict-and-child-health
#1
JOURNAL ARTICLE
Hannah M C Schreier, Mark E Feinberg, Damon E Jones, Aishwarya Ganguli, Caitlin Givens, Jennifer Graham-Engeland
Interparental conflict is known to negatively impact child well-being, including behavioral and physiological well-being. Children's empathy - that is, vicariously experiencing others' emotions - may increase children's sensitivity to and the biological repercussions of interparental conflict. Although empathy represents a valued trait and is an important part of socioemotional development, its influence on children's physical health is unknown. This study examined whether empathy moderates the association between perceived interparental conflict and both child systemic inflammation and parent-rated overall child health in a sample of children between the ages of seven to nine...
February 24, 2024: Brain, Behavior, and Immunity
https://read.qxmd.com/read/38389292/self-reported-pain-during-different-phases-of-orthodontic-treatment-with-fixed-appliance-a-multi-centre-randomized-controlled-trial-in-adolescents-with-crowding
#2
JOURNAL ARTICLE
Kristina Johansson, Linda Bokander Matilainen, Michal Wiaderny, Henrik Berlin, Gunilla Klingberg, Houda Ghiasi, Anna Brechter, Liselotte Paulsson
OBJECTIVES: To compare self-reported pain levels across various treatment phases using passive self-ligating (Damon) and conventional (Victory) standardized fixed appliance systems. MATERIALS AND METHODS: Adolescents (12-17 years old) with crowding and displaced teeth, planned for non-extraction treatment, were recruited from four orthodontic clinics. They were randomized into stratified blocks (1:1 ratio) using concealed allocation to receive Damon Q™ (34 boys, 28 girls) or Victory™ (39 boys, 31 girls)...
February 22, 2024: Orthodontics & Craniofacial Research
https://read.qxmd.com/read/38371222/mandible-fractures-undergoing-transfer-rarely-require-acute-intervention
#3
JOURNAL ARTICLE
Damon R T McIntire, Carole S L Spake, Charles C Jehle, Marten N Basta, Joseph W Crozier, Albert S Woo
STUDY DESIGN: A retrospective review was conducted of all patients with mandibular fractures who were evaluated by plastic surgery at a Level I trauma center between January 1, 2017 and May 1, 2020. Data including demographic characteristics, mechanism of injury, type of presentation (e.g., primary or transfer), treatment plan, and time to intervention were recorded. OBJECTIVE: Mandibular fractures are common traumatic injuries. Because these injuries are managed by surgical specialists, these patients are often emergently transferred to tertiary care hospitals...
March 2024: Craniomaxillofacial Trauma & Reconstruction
https://read.qxmd.com/read/38369167/shape-constrained-deformable-brain-segmentation-methods-and-quantitative-validation
#4
JOURNAL ARTICLE
Lyubomir Zagorchev, Damon E Hyde, Chen Li, Fabian Wenzel, Nick Fläschner, Arne Ewald, Stefani O'Donoghue, Kelli Hancock, Ruo Xuan Lim, Dennis C Choi, Eddie Kelly, Shruti Gupta, Jessica Wilden
MRI-guided neuro interventions require rapid, accurate, and reproducible segmentation of anatomical brain structures for identification of targets during surgical procedures and post-surgical evaluation of intervention efficiency. Segmentation algorithms must be validated and cleared for clinical use. This work introduces a methodology for shape-constrained deformable brain segmentation, describes the quantitative validation used for its clinical clearance, and presents a comparison with manual expert segmentation and FreeSurfer, an open source software for neuroimaging data analysis...
February 16, 2024: NeuroImage
https://read.qxmd.com/read/38306657/venous-and-arterial-thrombosis-in-patients-with-vexas-syndrome
#5
JOURNAL ARTICLE
Yael Kusne, Atefeh Ghorbanzadeh, Alina Dulau Florea, Ruba N Shalhoub, Pedro Emilio Alcedo Andrade, Khanh Nghiem, Marcela A Ferrada, Alexander Hines, Kaitlin A Quinn, Sumith R Panicker, Amanda K Ombrello, Kaaren K Reichard, Ivana Darden, Wendy Goodspeed, Jibran Durrani, Lorena Wilson, Horatiu Olteanu, Terra L Lasho, Daniel L Kastner, Kenneth J Warrington, Abhishek A Mangaonkar, Ronald S Go, Raul C Braylan, David B Beck, Mrinal M Patnaik, Neal S Young, Katherine R Calvo, Ana Casanegra, Peter C Grayson, Matthew J Koster, Colin O Wu, Yogendra Kanthi, Bhavisha A Patel, Damon E Houghton, Emma M Groarke
VEXAS (Vacuoles, E1 enzyme, X-linked, Autoinflammatory, Somatic) syndrome, caused by somatic mutations in UBA1, is an autoinflammatory disorder with diverse systemic manifestations. Thrombosis is a prominent clinical feature of VEXAS. The risks factors and frequency of thrombosis in VEXAS are not well described, due to the disease's new discovery and paucity of large databases. We evaluated 119 VEXAS patients for venous and arterial thrombosis and correlated their presence with clinical outcomes and survival...
February 2, 2024: Blood
https://read.qxmd.com/read/38305137/the-fondazione-toscana-gabriele-monasterio-app-a-digital-health-system-to-improve-wellbeing-of-inpatients-with-heart-or-lung-disease
#6
JOURNAL ARTICLE
Alberto Aimo, Ilaria Tono, Eleonora Benelli, Paolo Morfino, Giorgia Panichella, Anna Luce Damone, Maria Filomena Speltri, Edoardo Airò, Simonetta Monti, Claudio Passino, Maila Lazzarini, Sabina De Rosis, Sabina Nuti, Maria Sole Morelli, Chiara Evangelista, Roberta Poletti, Michele Emdin, Massimo Bergamasco
BACKGROUND: An app providing material for education and entertaining is a possible way to support patients and healthcare providers in achieving person-centered care. METHODS: An app tailored on the Fondazione Toscana Gabriele Monasterio (FTGM), a research hospital treating cardiac and lung disorders, was created. A pilot evaluation project was conducted on consecutive patients hospitalized for heart or lung disorders. Patients were asked to complete an assessment questionnaire...
January 31, 2024: Journal of Cardiovascular Medicine
https://read.qxmd.com/read/38281350/the-impact-of-referring-hospital-resources-on-interfacility-overtriage-a-population-based-analysis
#7
JOURNAL ARTICLE
Bourke W Tillmann, Avery B Nathens, Matthew P Guttman, Priscila Pequeno, Damon C Scales, Petros Pechlivanoglou, Barbara Haas
BACKGROUND: Nearly half of patients transferred from non-trauma to trauma centres have minor injuries. The transfer of patients with minor injuries to trauma centres is not associated with any known patient benefit and represents an opportunity to reduce healthcare costs and improve patient experience. In this study, we evaluated the relationship between hospital resources and overtriage, with the objective of identifying targets for system-level intervention. METHODS: We conducted a population-based cohort study of adults, age ≥ 16, presenting with minor injuries to non-trauma centres in Ontario, Canada (2009-2020)...
January 17, 2024: Injury
https://read.qxmd.com/read/38182562/quick-model-based-viscoelastic-clot-strength-predictions-from-blood-protein-concentrations-for-cybermedical-coagulation-control
#8
JOURNAL ARTICLE
Damon E Ghetmiri, Alessia J Venturi, Mitchell J Cohen, Amor A Menezes
Cybermedical systems that regulate patient clotting in real time with personalized blood product delivery will improve treatment outcomes. These systems will harness popular viscoelastic assays of clot strength such as thromboelastography (TEG), which help evaluate coagulation status in numerous conditions: major surgery (e.g., heart, vascular, hip fracture, and trauma); liver cirrhosis and transplants; COVID-19; ICU stays; sepsis; obstetrics; diabetes; and coagulopathies like hemophilia. But these measurements are time-consuming, and thus impractical for urgent care and automated coagulation control...
January 5, 2024: Nature Communications
https://read.qxmd.com/read/38164008/comparison-of-pain-levels-on-patients-undergoing-fixed-orthodontic-treatment-with-2-different-self-ligating-bracket-systems
#9
JOURNAL ARTICLE
Mustafa Dedeoğlu, Ömür Polat Özsoy
OBJECTIVE: Comparison of pain levels of patients treated with 2 different passive self-ligating bracket systems right after initial archwire placement. METHODS: A total of 34 patients with mild crowding were allocated randomly to 2 groups to be treated using 2 different self-ligating brackets. 0.014 inch copper nitinol and 0.014 inch superelastic nitinol archwires were selected as the initial archwire for Damon Q and SmartClip SL3 systems respectively. Seven page questionnaires that consisted of 3 visual analogue scales were handled to patients to mark their pain levels while chewing, biting with anterior teeth, and biting with posterior teeth at 2nd hour, 6th hour, 2nd day, 3rd day, and 7t h day time intervals...
December 29, 2023: Turkish Journal of Orthodontics
https://read.qxmd.com/read/38076944/chatgpt-influence-on-medical-decision-making-bias-and-equity-a-randomized-study-of-clinicians-evaluating-clinical-vignettes
#10
Ethan Goh, Bryan Bunning, Elaine Khoong, Robert Gallo, Arnold Milstein, Damon Centola, Jonathan H Chen
In a randomized, pre-post intervention study, we evaluated the influence of a large language model (LLM) generative AI system on accuracy of physician decision-making and bias in healthcare. 50 US-licensed physicians reviewed a video clinical vignette, featuring actors representing different demographics (a White male or a Black female) with chest pain. Participants were asked to answer clinical questions around triage, risk, and treatment based on these vignettes, then asked to reconsider after receiving advice generated by ChatGPT+ (GPT4)...
November 27, 2023: medRxiv
https://read.qxmd.com/read/38069782/service-guidelines-models-and-protocols-for-integrating-rehabilitation-services-in-primary-healthcare-in-brazil-russia-india-china-and-south-africa-a-scoping-review
#11
JOURNAL ARTICLE
Lebogang Maseko, Hellen Myezwa, Natalie Benjamin-Damons, Denise Franzsen, Fasloen Adams
PURPOSE: The WHO emphasises that rehabilitation services must be integrated into primary healthcare as an inherent part of universal health coverage. However, there is limited research on the integration of rehabilitation services in primary healthcare in low- and middle-income countries. The purpose of this paper is to identify and describe the literature on service guidelines, models, and protocols that support the integration of rehabilitation services in primary healthcare in the BRICS countries (Brazil, Russia, India, China, and South Africa)...
December 9, 2023: Disability and Rehabilitation
https://read.qxmd.com/read/38059362/resistance-exercise-training-in-individuals-with-and-without-cardiovascular-disease-2023-update-a-scientific-statement-from-the-american-heart-association
#12
REVIEW
Amanda E Paluch, William R Boyer, Barry A Franklin, Deepika Laddu, Felipe Lobelo, Duck-Chul Lee, Mary M McDermott, Damon L Swift, Allison R Webel, Abbi Lane
Resistance training not only can improve or maintain muscle mass and strength, but also has favorable physiological and clinical effects on cardiovascular disease and risk factors. This scientific statement is an update of the previous (2007) American Heart Association scientific statement regarding resistance training and cardiovascular disease. Since 2007, accumulating evidence suggests resistance training is a safe and effective approach for improving cardiovascular health in adults with and without cardiovascular disease...
January 16, 2024: Circulation
https://read.qxmd.com/read/38042844/-it-feels-like-i-m-coming-to-a-friend-s-house-an-interpretive-descriptive-study-of-an-integrated-care-site-offering-ioat-dr-peter-centre
#13
JOURNAL ARTICLE
Sophia Dobischok, José R Carvajal, Kyle Turner, Kaitlyn Jaffe, Eisha Lehal, Sarinn Blawatt, Casey Redquest, Rosalind Baltzer Turje, Patrick McDougall, Bryce Koch, Cheryl McDermid, Damon Hassan, Scott Harrison, Eugenia Oviedo-Joekes
BACKGROUND: Injectable opioid agonist treatment (iOAT) has proven to be a safe and effective treatment option for severe opioid use disorder (OUD). Yet, iOAT is often isolated from other health and social services. To align with a person-centered care approach, iOAT can be embedded in sites that combine systems and services that have been historically fragmented and that address multiple comorbidities (integrated care sites). The present study investigates the addition of iOAT at an integrated care in Vancouver, British Columbia...
December 2, 2023: Addiction Science & Clinical Practice
https://read.qxmd.com/read/38009409/automated-artificial-intelligence-based-three-dimensional-comparison-of-orthodontic-treatment-outcomes-with-and-without-piezocision-surgery
#14
JOURNAL ARTICLE
Marcela Gurgel, Maria Antonia Alvarez, Juan Fernando Aristizabal, Baptiste Baquero, Maxine Gillot, Najla Al Turkestani, Felicia Miranda, Aron Aliaga-Del Castillo, Jonas Bianchi, Antonio Carlos de Oliveira Ruellas, Marcos Ioshida, Marilia Yatabe, Diego Rey, Juan Prieto, Lucia Cevidanes
OBJECTIVE(S): This study aims to evaluate the influence of the piezocision surgery in the orthodontic biomechanics, as well as in the magnitude and direction of tooth movement in the mandibular arch using novel artificial intelligence (AI)-automated tools. MATERIALS AND METHODS: Nineteen patients, who had piezocision performed in the lower arch at the beginning of treatment with the goal of accelerating tooth movement, were compared to 19 patients who did not receive piezocision...
November 27, 2023: Orthodontics & Craniofacial Research
https://read.qxmd.com/read/37978271/modeling-phenotypic-heterogeneity-towards-evolutionarily-inspired-osteosarcoma-therapy
#15
JOURNAL ARTICLE
Darcy L Welch, Brooke L Fridley, Ling Cen, Jamie K Teer, Sean J Yoder, Fredrik Pettersson, Liping Xu, Chia-Ho Cheng, Yonghong Zhang, Mark G Alexandrow, Shengyan Xiang, Mark Robertson-Tessi, Joel S Brown, Jonathan Metts, Andrew S Brohl, Damon R Reed
Osteosarcoma is the most common bone sarcoma in children and young adults. While universally delivered, chemotherapy only benefits roughly half of patients with localized disease. Increasingly, intratumoral heterogeneity is recognized as a source of therapeutic resistance. In this study, we develop and evaluate an in vitro model of osteosarcoma heterogeneity based on phenotype and genotype. Cancer cell populations vary in their environment-specific growth rates and in their sensitivity to chemotherapy. We present the genotypic and phenotypic characterization of an osteosarcoma cell line panel with a focus on co-cultures of the most phenotypically divergent cell lines, 143B and SAOS2...
November 17, 2023: Scientific Reports
https://read.qxmd.com/read/37956401/development-and-pilot-of-an-mpox-severity-scoring-system-mpox-sss
#16
JOURNAL ARTICLE
Jason Zucker, Jacob McLean, Simian Huang, Clare DeLaurentis, Shauna Gunaratne, Kate Stoeckle, Marshall J Glesby, Timothy J Wilkin, William Fischer, John T Brooks, Inger Damon
Clinical severity scores facilitate comparisons to understand risk factors for severe illness. For the 2022 multinational monkeypox Clade IIb virus outbreak, we developed a 7-item mpox severity scoring system (MPOX-SSS) with initial variables refined based on data availability and parameter correlation. Application of MPOX-SSS to the first 200 patients diagnosed with mpox revealed higher scores in those treated with tecovirimat, presenting >3 days after symptom onset and with CD4 counts <200 cells/mm3 ...
November 13, 2023: Journal of Infectious Diseases
https://read.qxmd.com/read/37847251/posttreatment-stability-following-therapy-using-passive-self-ligating-brackets-extraction-vs-nonextraction
#17
JOURNAL ARTICLE
Babak Sayahpour, Diana Lau, Sara Eslami, Sarah Buehling, Stefan Kopp, Abdolreza Jamilian, Sachin Chhatwani
PURPOSE: This study aimed to evaluate the effects of lower premolar extraction on posttreatment stability one year following fixed orthodontic treatment with passive self-ligating brackets (Damon system, Ormco, Orange, CA, USA). METHODS: All patients were treated with fixed orthodontic appliances using passive self-ligating brackets (Damon). For retention, removable Hawley retainers were used. Two groups of patients were included in the study. Each group consisted of 23 patients: group Ex consisted of 10 male and 13 female patients (13...
October 17, 2023: Journal of Orofacial Orthopedics
https://read.qxmd.com/read/37822141/system-failure-systemic-inflammation-following-spinal-cord-injury
#18
REVIEW
Damon J DiSabato, Christina M Marion, Katherine A Mifflin, Anthony N Alfredo, Kyleigh A Rodgers, Kristina A Kigerl, Phillip G Popovich, Dana M McTigue
Spinal cord injury (SCI) affects hundreds of thousands of people in the United States, and while some effects of the injury are broadly recognized (deficits to locomotion, fine motor control, and quality of life), the systemic consequences of SCI are less well-known. The spinal cord regulates systemic immunological and visceral functions; this control is often disrupted by the injury, resulting in viscera including the gut, spleen, liver, bone marrow, and kidneys experiencing local tissue inflammation and physiological dysfunction...
October 11, 2023: European Journal of Immunology
https://read.qxmd.com/read/37738666/behavioral-health-integrated-support-network-bhisn
#19
JOURNAL ARTICLE
Steven M Cain, Sara Bennetts, Gage Riddoch, Damon Pratt, Audra Stock, Veronica Isidron, Maria Lopez, Matthew Orchowsky
INTRODUCTION: This article reviews process and performance of an innovative effort leveraging virtual health to manage unmet demand for behavioral health and substance use disorder services across a large military region. This effort began in June 2022 and included nearly all of the Defense Health Agency Region-Europe's military behavioral health and substance abuse clinics participating. The two goals of improving access to behavioral health and substance use services for active duty service members and improving utilization of the military clinics were employed...
September 21, 2023: Military Medicine
https://read.qxmd.com/read/37729775/the-impact-of-covid-19-pandemic-on-free-tissue-transfer-outcomes-a-nsqip-analysis
#20
JOURNAL ARTICLE
Cynthia T Yusuf, Christopher D Lopez, Salih Colakoglu, Carisa M Cooney, Damon S Cooney
BACKGROUND: The COVID-19 pandemic significantly impacted hospital resources and patient care, although its effect on free tissue transfer procedures is poorly understood. We conducted the current study to investigate the potential impact of COVID-19 and its accompanying system shut-downs on the surgical outcomes of patients undergoing free flap procedures. METHODS: Patients undergoing free tissue transfer procedures were identified from the National Surgical Quality Improvement Program (NSQIP) database from 2016 to 2020...
June 28, 2023: Journal of Plastic, Reconstructive & Aesthetic Surgery: JPRAS
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