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Condyloma acuminatum

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https://www.readbyqxmd.com/read/28632472/recalcitrant-giant-condyloma-acuminatum-treated-successfully-with-a-novel-combination-of-mycobacterium-indicus-pranii-immunotherapy-and-acitretin
#1
Geeti Khullar, Tarun Narang, Dipankar De, Uma Nahar Saikia, Sunil Dogra, Sanjeev Handa
Giant condyloma acuminatum occurs infrequently in children and adolescents. It is a challenging condition which is difficult to treat with both surgical and medical modalities. We present a case of a 15-year-old boy with giant condyloma acuminatum of the glans penis refractory to several therapeutic modalities. The lesions were treated successfully with a novel combination of Mycobacterium indicus pranii immunotherapy and acitretin. There was no recurrence of lesions after two years of follow-up.
January 1, 2017: International Journal of STD & AIDS
https://www.readbyqxmd.com/read/28620555/a-discussion-of-high-risk-hpv-in-a-6-year-old-female-survivor-of-child-sexual-abuse
#2
Connie D Cao, Lena Merjanian, Joelle Pierre, Adrian Balica
BACKGROUND: Human papilloma viruses (HPVs) cause a variety of clinical manifestations in children including skin warts, laryngeal papillomas, and condyloma acuminatum. Whereas the mode of transmission is well understood and management of HPV infection is clearly defined by guidelines in adults, less is known about the mode of transmission, natural history of disease, and appropriate management of high-risk anogenital HPV infections in children. CASE: The patient is a previously healthy 6-year-old female who presented with multiple vaginal lesions causing pain and discomfort and was diagnosed with HPV 18 positive CIN I...
2017: Case Reports in Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28601547/intranasal-condyloma-acuminatum-with-malignant-transformation
#3
Tengchin Wang, Chieh Jen Wu
No abstract text is available yet for this article.
June 7, 2017: American Journal of Medicine
https://www.readbyqxmd.com/read/28534469/optimization-of-a-decoction-process-for-an-herbal-formula-using-a-response-surface-methodology
#4
Xian-Fei Zhang, Jun-Li Yang, Juan Chen, Yan-Ping Shi
<p>An herbal formula, Huang-Qi-Liu-Yi Tang, is a prescription medicine that has been commonly used for the treatment of prostatitis and condyloma acuminatum over the last thousand years. In this study, response surface methodology, with a Box–Behnken design (BBD), was used to optimize the decoction conditions of an herbal formula. Astragaloside, calycosin-7-glucoside, glycyrrhizic acid, liquiritin, polysaccharide, and extractum were used as multiple evaluation markers. Soak time, water-to-medicinal herb ratio, and extraction time were determined as the three main variables by single-factor experiments and further optimized to obtain the maximum yields for the six marker compounds...
May 22, 2017: Journal of AOAC International
https://www.readbyqxmd.com/read/28499554/effectiveness-of-hpv-vaccines-against-genital-warts-in-women-from-valencia-spain
#5
Esther Navarro-Illana, Mónica López-Lacort, Pedro Navarro-Illana, Juan José Vilata, Javier Diez-Domingo
OBJECTIVES: To assess the effectiveness of the HPV vaccines in preventing genital warts in young women. DESIGN: Population-based study using health databases. SETTING: Valencian Community (Spain). PARTICIPANTS: All girls and women aged 14-19years who were registered in the Valencian Community between January 2009 and December 2014 (n=279,787). MAIN OUTCOME MEASURES: Incident cases of genital warts were defined as the first activation of diagnosis code ICD-9-CM 078...
June 5, 2017: Vaccine
https://www.readbyqxmd.com/read/28487788/giant-condyloma-acuminatum-of-vulva-in-an-hiv-infected-woman
#6
Athanase Lilungulu, Bonaventura C T Mpondo, Abdallah Mlwati, Dismas Matovelo, Albert Kihunrwa, Balthazar Gumodoka
First described in 1925, giant condyloma acuminatum also known as Buschke-Löwenstein tumor (BLT) is a benign, slow-growing, locally destructive cauliflower-like lesion usually in the genital region. The disease is usually locally aggressive and destructive with a potential for malignant transformation. The causative organism is human papilloma virus. The most common risk factor is immunosuppression with HIV; however, any other cause of immunodeficiency can be a predisposing factor. We present a case of 33-year-old female patient, a known HIV patient on antiretroviral therapy for ten months...
2017: Case Reports in Infectious Diseases
https://www.readbyqxmd.com/read/28428680/coexistence-of-condylomata-acuminata-with-warty-squamous-cell-carcinoma-and-squamous-cell-carcinoma
#7
Mirna Erman-Vlahovic, Jelena Vlahovic, Milanka Mrcela, Zlatko Hrgovic
INTRODUCTION: Condyloma acuminatum has previously been considered to be a benign growth with no malignant potential, but a review of the literature supports the concept that condylomata acuminata may precede or be associated with invasive squamous cell carcinoma (ISCC) or warty squamous cell carcinoma (WSCC). CASE REPORT: We present a clinical case of a 58-year old woman with large, slow-growing, exophytic tumor of external genitalia shaped like a cauliflower with the propagation to both legs and behind...
February 2017: Medical Archives
https://www.readbyqxmd.com/read/28396786/giant-condyloma-acuminatum-malignant-transformation
#8
Ioannis K Papapanagiotou, Kyriaki Migklis, Georgia Ioannidou, Dimitra Xesfyngi, Vasileios Kalles, Theodoros Mariolis-Sapsakos, Emmanouil Terzakis
Giant condyloma acuminata are associated with malignant transformation in up to 50% of cases, high recurrence rate, and poor prognosis. Treatment strategies have included wide local excision, abdominopelvic resection, and addition of radiotherapy and adjuvant and/or neoadjuvant systemic chemotherapy.
April 2017: Clinical Case Reports
https://www.readbyqxmd.com/read/28377892/innumerable-condyloma-acuminatum-tumors-of-the-bladder
#9
Alexandra J Murray, Trinity J Bivalacqua, Nikolai A Sopko
Condylomata acuminata caused by human papillomavirus (HPV), a sexually transmitted virus, are rarely seen beyond the external genitalia and anal region. Here, a patient with innumerable condyloma acuminatum of the bladder is presented. Attempted surgical resection was performed and intraoperative photographs are presented.
May 2017: Urology Case Reports
https://www.readbyqxmd.com/read/28300722/effect-of-5-aminolevulinic-acid-photodynamic-therapy-on-keratinocyte-proliferation-and-apoptosis-in-condyloma-acuminatum
#10
Guangwen Yin, Ke Sha, Bingjie Cai, Fangfang Li, Xuyang Li, Xianxian Xia, Xinxin Pan
BACKGROUND: The effect of 5-aminolevulinic acid photodynamic therapy on keratinocyte proliferation and apoptosis in condyloma acuminatum tissues was evaluated. METHODS: An immunohistochemical method and TdT-mediated dUTP nick end labeling were performed to detect the positive expression of the keratinocyte proliferation-related gene Ki-67 and apoptosis, respectively, in condyloma acuminatum tissues. RESULTS: Of 52 cases, 44 showed positive expression of Ki-67 in condyloma acuminatum keratinocytes before the treatment, with a positive expression rate of 84...
March 11, 2017: Photodiagnosis and Photodynamic Therapy
https://www.readbyqxmd.com/read/28089720/condyloma-acuminatum-of-urinary-bladder-in-a-male-renal-transplant-recipient-a-diagnostic-and-therapeutic-challenge
#11
Aruna Nambirajan, Abhishek Kumar Shukla, Sandeep R Mathur, Hemanth Kumar, Rajeev Kumar, Dipankar M Bhowmik, Ashok Singh, Deepali Jain, Mehar Chand Sharma, Seema Kaushal
No abstract text is available yet for this article.
January 4, 2017: Clinical Genitourinary Cancer
https://www.readbyqxmd.com/read/28074214/-buschke-lowenstein-tumors
#12
REVIEW
M Sporkert, A Rübben
BACKGROUND: A giant condyloma acuminatum which shows destructive growth but lacking invasion is designated as a Buschke-Lowenstein tumor (BLT). OBJECTIVES: Classification of the BLT and therapeutic guidelines are provided. MATERIALS AND METHODS: A MEDLINE literature search from 2006-2016 was performed. RESULTS: Induction through low-risk mucosotropic human papillomavirus (HPV) infection separates BLT from verrucous carcinoma...
March 2017: Der Hautarzt; Zeitschrift Für Dermatologie, Venerologie, und Verwandte Gebiete
https://www.readbyqxmd.com/read/28042250/underwater-endoscopic-mucosal-resection-of-a-condyloma-acuminatum-of-the-anal-canal
#13
Kenta Hamada, Noriya Uedo, Yasuhiko Tomita, Ryu Ishihara
No abstract text is available yet for this article.
2017: Annals of Gastroenterology: Quarterly Publication of the Hellenic Society of Gastroenterology
https://www.readbyqxmd.com/read/27922892/galectin-3-expression-in-benign-and-malignant-skin-diseases-with-epidermal-hyperplasia
#14
Ze-Xin Jiang, Guo-Zhen Tan, Zhen-Rui Shi, Yu-Ping Zhang, Yan-Fang Han, Liangchun Wang
Galectin-3 has been suggested relative to tumor genesis, progression, and metastasis in basal cell carcinoma and squamous cell carcinoma that are the most common skin cancers characterized by malignant epidermal proliferation. In this study, we evaluated galectin-3 expression in seborrheic keratosis, keratoacanthoma, and infectious diseases including verruca vulgaris, condyloma acuminatum, and chromoblastomycosis that are pathologically featured by benign epidermal proliferation. Galectin-3 expression was shown by immunohistochemical staining and quantified using the Image Pro Plus V6...
November 7, 2016: American Journal of Dermatopathology
https://www.readbyqxmd.com/read/27872135/successful-improvement-of-buschke-l%C3%A3-wenstein-tumour-in-an-hiv-infected-patient-with-antiretroviral-therapy-alone
#15
Camille Grodner, Aurélia Henn, Jean-Daniel Lelièvre, Sébastien Gallien
Buschke-Löwenstein tumour (BLT), also defined as giant condyloma acuminatum, is a rare exophytic tumour affecting the anogenital and perianal regions associated with human papillomavirus (HPV) infections, with a potential of malignant transformation and which is at a greater risk in T-cell mediated immunodeficient patients. Different therapeutic options, alone or in combination, have been reported for the treatment of BLT including local therapy but wide surgical local excision is however recommended as the most important therapeutic intervention...
November 21, 2016: BMJ Case Reports
https://www.readbyqxmd.com/read/27819643/giant-perineal-condyloma-acuminatum-buschke-lowenstein-tumour-a-case-report
#16
D C Badiu, C A Manea, M Mandu, V Chiperi, I E Marin, C Mehedintu, C C Popa, O I David, E Bratila, V T Grigorean
The giant condyloma acuminatum, also known as Buschke- Lowenstein tumor (BLT), is a rare sexually-transmitted disease. Moreover, the condyloma acuminatum produced by Human Papilloma Virus (HPV) infection becomes one the most common sexually-transmitted infection which affects the perineal region. Under such situations, the first therapeutic option is surgical excision. The objective of this article is to present a case in which the tumor has reached giant dimensions and also to stress the importance of an in toto resection, taking into account the high rate of recurrence and the significant potential of malignant transformation of BLT...
2016: Chirurgia
https://www.readbyqxmd.com/read/27801758/metastatic-urothelial-carcinoma-to-the-uterine-cervix-a-case-report-of-a-rare-entity-and-review-of-the-diagnostic-differential
#17
Sharon B Sams, Julie A Rosser
Urothelial carcinoma (UC) rarely metastasizes to the gynecologic tract, occurring in descending order of frequency, within the vagina, uterus, ovaries, and cervix. Significant morphologic overlap exists between primary gynecologic squamous lesions (both benign and malignant) and metastatic UC, thus potentially hindering a timely and accurate diagnosis. We present a case of UC metastatic to the uterine cervix in a 69-year-old female initially found to have noninvasive high-grade papillary UC of the bladder. Complaints of vaginal spotting lead to identification and biopsy of a mass in the uterine cervix...
October 31, 2016: International Journal of Gynecological Pathology
https://www.readbyqxmd.com/read/27716987/efficacy-of-imidazolquinoline-on-treatment-of-condyloma-acuminatum-of-the-buccal-mucosa
#18
Davi Silva Carvalho Curi, Patrícia Miranda Leite-Ribeiro, Vinicius Rabelo Torregrossa, Vinicius Costa Vieira, Viviane Almeida Sarmento
The condylomata acuminata is a benign epithelial neoplasm induced by papillomavirus, and it is characterized by the proliferation of stratified squamous epithelial tissue that affects the anogenital and oral mucosa. It is considered to be a sexually transmitted disease and has a higher prevalence in individuals infected with human immunodeficiency virus. Various therapies have been used for the removal of lesions, such as cryotherapy, surgical laser and surgical excision, which are painful and scarring. These techniques, however, do not eliminate the virus and relapses are common shortly after treatment...
September 26, 2016: Special Care in Dentistry
https://www.readbyqxmd.com/read/27659432/risk-factors-for-urethral-condyloma-among-heterosexual-young-male-patients-with-condyloma-acuminatum-of-penile-skin
#19
Jong Kwan Park, Yu Seob Shin
To our knowledge, this is the first study that focuses on risk factor of urethral condyloma (UC). The subjects of our study included genital warts patients who had been diagnosed as having condyloma acuminatum of penile skin (CAPS) with/without UC. Relationship with UC of number of life time female partners, co-infection with urethritis, circumcision status, number of CAPS and wart diameter were studied by use of multivariate analysis. Co-infection with urethritis, circumcision status were risk factors of UC in heterosexual young male patients with CAPS...
September 2016: Infection & Chemotherapy
https://www.readbyqxmd.com/read/27551519/transcription-factor-7-like-1-dysregulates-keratinocyte-differentiation-through-upregulating-lipocalin-2
#20
M Xu, Y Zhang, H Cheng, Y Liu, X Zou, N Zhan, S Xiao, Y Xia
Recent studies strongly suggested that transcription factor 7-like 1 (Tcf7l1, also known as Tcf3) is involved in the differentiation of several types of cells, and demonstrated that Tcf7l1 modulates keratinocytes physiologically through regulating lipocalin 2 (LCN2), a key regulator of cell differentiation. To reveal the potential role of Tcf7l1 in the dysregulation of keratinocyte differentiation, both Tcf7l1 and LCN2 were determined in a variety of skin disorders. The in vitro effect of Tcf7l1 on keratinocyte differentiation was studied by culturing SCC-13 cells, and the human foreskin keratinocytes (HFKs) that were transfected with vectors for overexpressing human papillomavirus E6/E7 or Tcf7l1 genes...
2016: Cell Death Discovery
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