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https://www.readbyqxmd.com/read/28110475/pattern-recognition-of-spectral-entropy-features-for-detection-of-alcoholic-and-control-visual-erp-s-in-multichannel-eegs
#1
T K Padma Shri, N Sriraam
This paper presents a novel ranking method to select spectral entropy (SE) features that discriminate alcoholic and control visual event-related potentials (ERP'S) in gamma sub-band (30-55 Hz) derived from a 64-channel electroencephalogram (EEG) recording. The ranking is based on a t test statistic that rejects the null hypothesis that the group means of SE values in alcoholics and controls are identical. The SE features with high ranks are indicative of maximal separation between their group means. Various sizes of top ranked feature subsets are evaluated by applying principal component analysis (PCA) and k-nearest neighbor (k-NN) classification...
January 21, 2017: Brain Informatics
https://www.readbyqxmd.com/read/28110457/reduced-proliferation-and-colony-formation-of-head-and-neck-squamous-cell-carcinoma-hnscc-after-dual-targeting-of-egfr-and-hedgehog-pathways
#2
Hannes Liebig, Georg Günther, Marlen Kolb, Christian Mozet, Andreas Boehm, Andreas Dietz, Gunnar Wichmann
PURPOSE: The hedgehog signalling pathway (Hh) is frequently active in head and neck squamous cell carcinoma (HNSCC). Overexpressed Hh associates with poor prognosis. The Hh inhibitor vismodegib targets smoothened, and based on molecular data, may prevent resistance to EGFR targeting. METHODS: To elucidate potential roles of vismodegib in HNSCC therapy, its sole effects and those combined with cisplatin, docetaxel, and cetuximab on HNSCC cell lines were assessed by MTT metabolisation and BrdU incorporation...
January 21, 2017: Cancer Chemotherapy and Pharmacology
https://www.readbyqxmd.com/read/28110447/hemispheric-lateralization-of-resting-state-functional-connectivity-of-the-ventral-striatum-an-exploratory-study
#3
Sheng Zhang, Sien Hu, Herta H Chao, Chiang-Shan R Li
Resting-state functional connectivity (rsFC) is widely used to examine cerebral functional organization. The ventral striatum (VS) is critical to motivated behavior, with extant studies suggesting functional hemispheric asymmetry. The current work investigated differences in rsFC between the left (L) and right (R) VS and explored gender differences in the extent of functional lateralization. In 106 adults, we computed a laterality index (fcLI) to query whether a target region shows greater or less connectivity to the L vs R VS...
January 21, 2017: Brain Structure & Function
https://www.readbyqxmd.com/read/28110443/aerobic-endurance-training-does-not-protect-bone-against-poorly-controlled-type-1-diabetes-in-young-adult-rats
#4
Tom J Hazell, T Dylan Olver, Hana Kowalchuk, Matthew W McDonald, Adwitia Dey, Kenneth N Grisé, Earl G Noble, C W James Melling, Paula Lavery, Hope A Weiler
Streptozotocin (STZ)-induced type 1 diabetes mellitus (T1DM) decreases trabecular bone volume and bone strength in rodents. The current study investigated the potential protective effects of aerobic endurance training (AET) on bone in STZ-induced T1DM young adult rats. Sixty-four 8-week-old male Sprague-Dawley rats were randomly divided into 4 groups of 16: control non-T1DM sedentary (CS) and exercised (CX), T1DM sedentary (DS) and exercised (DX). Blood glucose was maintained at 9-15 mmol/L using subcutaneously implanted insulin pellets (Linplant, Linshin Canada, Inc...
January 21, 2017: Calcified Tissue International
https://www.readbyqxmd.com/read/28110428/exploring-relationship-between-spiritual-intelligence-religiosity-and-life-satisfaction-among-elderly-pakistani-muslims
#5
Khadeeja Munawar, Omama Tariq
This study is an effort to explore the relationship between spiritual intelligence, religiosity and life satisfaction in elderly Pakistani Muslims. A non-probability purposive sampling technique is utilized in order to recruit a sample of 100 elderly people (n = 50 men; n = 50 = women). Standardized questionnaires were used for collecting data. Data analysis was carried out using Pearson product-moment correlation analysis and independent sample t test. Findings revealed a significant correlation between spiritual intelligence, religiosity and life satisfaction among Pakistani elderly Muslim people...
January 21, 2017: Journal of Religion and Health
https://www.readbyqxmd.com/read/28110423/accuracy-and-evaluation-of-a-new-regression-equation-in-predicting-the-width-of-unerupted-permanent-canines-and-premolar-teeth
#6
A Bhatnagar, A A Sinha, S Chaudhary, N Manuja, H Kaur, T R Chaitra
AIM: To assess the applicability of two regression equations based on mixed dentition analysis and to propose and evaluate a new regression equation using the mandibular incisors and first permanent molars as predictors in calculating the size of unerupted permanent canines and premolar teeth in school children. METHODS: Dental study casts of 100 children (50 males and 50 females) aged 11-14 years from schools situated in Moradabad, Uttar Pradesh, India were used...
January 21, 2017: European Archives of Paediatric Dentistry: Official Journal of the European Academy of Paediatric Dentistry
https://www.readbyqxmd.com/read/28110407/in-vitro-performance-of-cad-cam-fabricated-implant-supported-temporary-crowns
#7
Martin Rosentritt, Philipp Raab, Sebastian Hahnel, Matthias Stöckle, Verena Preis
OBJECTIVES: The aim of this study was to investigate the in-vitro performance and fracture resistance of a temporary computer-aided designed and computer-aided manufactured polymethylmethacrylate (CAD/CAM-PMMA) material as implant or tooth-supported single crown with respect to the clinical procedure (permanently bonded/temporarily cemented). MATERIALS AND METHODS: Sixty-four crowns were fabricated on implants or human molar teeth simulating (a) labside procedure on prefabricated titanium-bonding base ([TiBase] implant crown bonded in laboratory, screwed chairside), (b) labside procedure ([LAB] standard abutment and implant crown bonded in laboratory, screwed chairside), (c) chairside procedure ([CHAIR] implant crown bonded to abutment), and (d) reference ([TOOTH] crowns luted on prepared human teeth)...
January 21, 2017: Clinical Oral Investigations
https://www.readbyqxmd.com/read/28110374/morphological-description-of-limbal-epithelium-searching-for-stem-cells-crypts-in-the-dog-cat-pig-cow-sheep-and-horse
#8
M Patruno, A Perazzi, T Martinello, A Blaseotto, E Di Iorio, I Iacopetti
The cornea provides protection and transparency to the eye, allowing an optimal sharpness view. In some pathological conditions the cornea is able to regenerate thanks to the presence of a stem cells reservoir present at the level of the transition area between cornea and sclera (limbus). Corneal cell therapies in Veterinary Medicine are really limited due to the lacking of knowledge about the anatomy of the limbal area, the putative presence of stem cells and their identification in domestic species. The aim of this study was to provide an overview of the main distinctive structural features of the sclero-corneal junction and conjunctival-corneal junction areas in some species of veterinary importance, using optic microscope observations of histological sections...
January 21, 2017: Veterinary Research Communications
https://www.readbyqxmd.com/read/28110279/walking-the-c4-pathway-past-present-and-future
#9
REVIEW
Robert T Furbank
The year 2016 marks 50 years since the publication of the seminal paper by Hatch and Slack describing the biochemical pathway we now know as C4 photosynthesis. This review provides insight into the initial discovery of this pathway, the clues which led Hatch and Slack and others to these definitive experiments, some of the intrigue which surrounds the international activities which led up to the discovery, and personal insights into the future of this research field. While the biochemical understanding of the basic pathways came quickly, the role of the bundle sheath intermediate CO2 pool was not understood for a number of years, and the nature of C4 as a biochemical CO2 pump then linked the unique Kranz anatomy of C4 plants to their biochemical specialization...
January 2017: Journal of Experimental Botany
https://www.readbyqxmd.com/read/28110151/selection-of-an-optimal-set-of-biomarkers-and-comparative-analyses-of-biological-age-estimation-models-in-korean-females
#10
Haemi Jee, Jaehyun Park
To date, an optimal working model which predicts biological age (BA) with a set of working biomarkers has not been devised to represent the Korean female population. Accuracy of prediction and applicability are required of an optimal set of commonly assessed biomarkers to provide information on the health status. The goal of this study was to identify a set of biomarkers that represent the aging process and to develop and compare different BA prediction models to elucidate the most fitting and applicable model for providing information on health status in the Korean female population...
January 12, 2017: Archives of Gerontology and Geriatrics
https://www.readbyqxmd.com/read/28110138/contributions-to-ultrasound-monitoring-of-the-process-of-milk-curdling
#11
Antonio Jiménez, Montaña Rufo, Jesús M Paniagua, Abel T Crespo, M Patricia Guerrero, M José Riballo
Ultrasound evaluation permits the state of milk being curdled to be determined quickly and cheaply, thus satisfying the demands faced by today's dairy product producers. This paper describes the non-invasive ultrasonic method of in situ monitoring the changing physical properties of milk during the renneting process. The basic objectives of the study were, on the one hand, to confirm the usefulness of conventional non-destructive ultrasonic testing (time-of-flight and attenuation of the ultrasound waves) in monitoring the process in the case of ewe's milk, and, on the other, to include other ultrasound parameters which have not previously been considered in studies on this topic, in particular, parameters provided by the Fast Fourier Transform technique...
January 10, 2017: Ultrasonics
https://www.readbyqxmd.com/read/28109987/mismatch-negativity-is-abnormal-but-not-lateralizing-in-temporal-lobe-epilepsy
#12
Lili Zhao, Dongmei An, Limei Mao, Xiangdong Tang, Li He, Dong Zhou
We investigated the changes of mismatch negativity (MMN) in patients with temporal lobe epilepsy (TLE) and explored the possible role of MMN in lateralizing their seizure focus. Thirty patients with TLE and thirty healthy controls were included. MMN was elicited in each subject. Patients with TLE were divided into three subgroups: unilateral left TLE; unilateral right TLE, and bilateral TLE. MMN amplitudes and latencies were compared between the patients with TLE and the control group, and also among the three subgroups of TLE, using repeated measures analyses of variance (ANOVA)...
January 18, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/28109946/novel-indolin-2-one-based-sulfonamides-as-carbonic-anhydrase-inhibitors-synthesis-in%C3%A2-vitro-biological-evaluation-against-carbonic-anhydrases-isoforms-i-ii-iv-and-vii-and-molecular-docking-studies
#13
Wagdy M Eldehna, Ghada H Al-Ansary, Silvia Bua, Alessio Nocentini, Paola Gratteri, Ayman Altoukhy, Hazem Ghabbour, Hanaa Y Ahmed, Claudiu T Supuran
Herein we present the design, synthesis, and biological evaluation of three different series of novel sulfonamides (3a-f, 6a-f and 9a-f) incorporating substituted indolin-2-one moieties (as tails) linked to benzenesulfonamide (as zinc anchoring moieties) through aminoethyl or (4-oxothiazolidin-2-ylidene)aminoethyl linkers. The synthesized sulfonamides were evaluated in vitro for their inhibitory activity against the following human (h) carbonic anhydrase (hCA, EC 4.2.1.1) isoforms, hCA I, II, IV and VII. All these isoforms were inhibited by the sulfonamides reported here in variable degrees...
January 11, 2017: European Journal of Medicinal Chemistry
https://www.readbyqxmd.com/read/28109932/accuracy-of-noncontrast-quiescent-interval-single-shot-lower-extremity-mr-angiography-versus-ct%C3%A2-angiography-for-diagnosis-of-peripheral-artery-disease-comparison-with-digital-subtraction-angiography
#14
Akos Varga-Szemes, Julian L Wichmann, U Joseph Schoepf, Pal Suranyi, Carlo N De Cecco, Giuseppe Muscogiuri, Damiano Caruso, Ricardo T Yamada, Sheldon E Litwin, Christian Tesche, Taylor M Duguay, Shivraman Giri, Rozemarijn Vliegenthart, Thomas M Todoran
OBJECTIVES: This study sought to evaluate the image quality and diagnostic accuracy of noncontrast quiescent-interval single-shot (QISS) magnetic resonance angiography (MRA) versus iodine-contrast computed tomography angiography (CTA) in patients with peripheral artery disease (PAD), with invasive digital subtraction angiography (DSA) as the reference standard. BACKGROUND: QISS is a recently introduced noncontrast MRA technique. Although the diagnostic accuracy of QISS is reportedly similar to that of contrast-enhanced MRA, its performance compared with contrast-enhanced CTA, the most frequently used noninvasive modality for evaluation of PAD, is unknown...
January 12, 2017: JACC. Cardiovascular Imaging
https://www.readbyqxmd.com/read/28109837/interspecific-variation-and-plasticity-in-hemoglobin-nitrite-reductase-activity-and-its-correlation-with-oxygen-affinity-in-vertebrates
#15
Frank B Jensen, Rasmus A H Kolind, Natashia S Jensen, Gabriella Montesanti, Tobias Wang
Deoxygenated hemoglobin (Hb) is a nitrite reductase that reduces naturally occurring nitrite to nitric oxide (NO), supplying physiological relevant NO under hypoxic conditions. The nitrite reductase activity is modulated by the allosteric equilibrium between the R and T structures of Hb that also determines oxygen affinity. In the present study we investigated nitrite reductase activity and O2 affinity in Hbs from ten different vertebrate species under identical conditions to disclose interspecific variations and allow an extended test for a correlation between the rate constant for nitrite reduction and O2 affinity...
January 18, 2017: Comparative Biochemistry and Physiology. Part A, Molecular & Integrative Physiology
https://www.readbyqxmd.com/read/28109770/modulation-of-the-antibiotic-activity-against-multidrug-resistant-strains-of-coumarins-isolated-from-rutaceae-species
#16
Sara A L Madeiro, Nathalie H P B Borges, Augusto L Souto, Pedro T R de Figueiredo, José P Siqueira-Junior, Josean F Tavares
The first occurrences and dissemination of resistant microorganisms led to the inefficacy of many antibiotics, available in the market nowadays, therefore, the search for new substances with antimicrobial activity from natural sources has gained a great importance. The purpose of this work is to evaluate the antibacterial activity and modulation of drug resistance in Staphylococcus aureus by coumarins such as bergapten, xantotoxin, isopimpinellin and imperatorin obtained from two Rutaceae species (Metrodorea mollis and Pilocarpus spicatus)...
January 18, 2017: Microbial Pathogenesis
https://www.readbyqxmd.com/read/28109703/investigation-of-anogenital-distance-as-a-diagnostic-tool-in-endometriosis
#17
Maria L Sánchez-Ferrer, Jaime Mendiola, Raquel Jiménez-Velázquez, Laura Cánovas-López, Shiana Corbalán-Biyang, Ana I Hernández-Peñalver, Ana Carmona-Barnosi, Ana B Maldonado-Cárceles, Maria T Prieto-Sánchez, Francisco Machado-Linde, Anibal Nieto, Alberto M Torres-Cantero
An association between anogenital distance (AGD) and endometriosis has been reported, suggesting that AGD may be a useful clinical tool in endometriosis. The predictive ability of AGD of women in discriminating presence and type of endometriosis was examined. A case-control study was conducted at the University Hospital 'Virgen de la Arrixaca', Murcia, Spain, between 2014 and 2015. A total of 114 participants diagnosed with endometriosis using ultrasound findings and 105 controls were recruited. Two AGD measurements were obtained: one from the anterior clitoral surface to the upper verge of the anus (AGDAC), and another one from the posterior fourchette to the upper verge of the anus (AGDAF)...
January 10, 2017: Reproductive Biomedicine Online
https://www.readbyqxmd.com/read/28109590/phenotypic-genetic-and-single-nucleotide-polymorphism-marker-associations-between-calf-diseases-and-subsequent-performance-and-disease-occurrences-of-first-lactation-german-holstein-cows
#18
M Mahmoud, T Yin, K Brügemann, S König
A total of 31,396 females born from 2010 to 2013 in 43 large-scale Holstein-Friesian herds were phenotyped for calf and cow disease traits using a veterinarian diagnosis key. Calf diseases were general disease status (cGDS), calf diarrhea (cDIA), and calf respiratory disease (cRD) recorded from birth to 2 mo of age. Incidences were 0.48 for cGDS, 0.28 for cRD, and 0.21 for cDIA. Cow disease trait recording focused on the early period directly after calving in first parity, including the interval from 10 d before calving to 200 d in lactation...
January 18, 2017: Journal of Dairy Science
https://www.readbyqxmd.com/read/28109500/is-routine-audiometric-testing-necessary-for-children-with-isolated-preauricular-lesions
#19
Grace T Wu, Conor Devine, Allen Xu, Katie Geelan-Hansen, Samantha Anne
INTRODUCTION: Preauricular lesions, including tags, pits, sinuses, and cysts are commonly seen. Some studies have shown increased incidence of hearing loss in these patients but other studies have failed to corroborate this finding. The purpose of this study is to evaluate the incidence of hearing loss in patients with isolated preauricular lesions. METHODS: Retrospective chart review of all pediatric otolaryngology patients seen at a tertiary academic center between 2008 and 2014...
February 2017: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/28109493/serum-periostin-level-is-not-associated-with-allergic-rhinitis-or-allergic-sensitization-in-korean-children
#20
Dong Young Kim, Jeong Hong Kim, Keun-Hwa Lee, Seong-Chul Hong, Hye-Sook Lee, Ju Wan Kang
OBJECTIVES: Periostin is a matricellular protein, synthesized in the airway epithelium and induced by interleukin (IL)-4 and IL-13. The significance of periostin as a biomarker of T helper type 2 cell (Th2)-induced airway inflammation, and as a measure of the response to Th2-targeted therapy, has recently been highlighted. We explored the relationship between serum periostin and allergic rhinitis in Korean children. METHODS: Data for fifth and sixth grade children from six randomly selected elementary schools located in Jeju and Seogwipo City, Korea, were investigated...
February 2017: International Journal of Pediatric Otorhinolaryngology
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