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Sedentary and elderly

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https://www.readbyqxmd.com/read/28421539/%C3%AE-synuclein-aggregates-with-%C3%AE-amyloid-or-tau-in-human-red-blood-cells-correlation-with-antioxidant-capability-and-physical-exercise-in-human-healthy-subjects
#1
Simona Daniele, Deborah Pietrobono, Jonathan Fusi, Caterina Iofrida, Lucia Chico, Lucia Petrozzi, Annalisa Lo Gerfo, Filippo Baldacci, Fabio Galetta, Gabriele Siciliano, Ubaldo Bonuccelli, Gino Santoro, Maria Letizia Trincavelli, Ferdinando Franzoni, Claudia Martini
Neurodegenerative disorders (NDs) are characterized by abnormal accumulation/misfolding of specific proteins, primarily α-synuclein (α-syn), β-amyloid1-42 (Aβ), and tau, in both brain and peripheral tissue. In addition to homo-oligomers, the role of α-syn interactions with Aβ or tau has gradually emerged. The altered protein accumulation has been related to both oxidative stress and physical activity; nevertheless, no correlation among the presence of peripheral α-syn hetero-aggregates, antioxidant capacity, and physical exercise has been discovered as of yet...
April 18, 2017: Molecular Neurobiology
https://www.readbyqxmd.com/read/28403681/atrophy-ultra-structural-disorders-severe-atrophy-and-degeneration-of-denervated-human-muscle-in-sci-and-aging-implications-for-their-recovery-by-functional-electrical-stimulation-updated-2017
#2
Helmut Kern, Cristian Hofer, Stefan Loefler, Sandra Zampieri, Paolo Gargiulo, Alfonc Baba, Andrea Marcante, Francesco Piccione, Amber Pond, Ugo Carraro
OBJECTIVES: Long-term lower motor neuron denervation of skeletal muscle is known to result in degeneration of muscle with replacement by adipose and fibrotic tissues. However, long-term survival of a subset of skeletal myofibers also occurs. METHODS: We performed transverse and longitudinal studies of patients with spinal cord injury (SCI), patients specifically complete Conus and Cauda Equina Syndrome and also of active and sedentary seniors which included analyses of muscle biopsies from the quadriceps m...
April 13, 2017: Neurological Research
https://www.readbyqxmd.com/read/28392959/restricted-blood-flow-exercise-in-sedentary-overweight-african-american-females-may-increase-muscle-strength-and-decrease-endothelial-function-and-vascular-autoregulation
#3
Vernon Bond, Bryan Heath Curry, Krishna Kumar, Sudhakar Pemminati, Vasavi Rakesh Gorantla, Kishan Kadur, Richard Mark Millis
OBJECTIVES: Exercise with partially restricted blood flow is a low-load, low-intensity resistance training regimen which may have the potential to increase muscle strength in the obese, elderly and frail who are unable to do high-load training. Restricted blood flow exercise has also been shown to affect blood vessel function variably and can, therefore, contribute to blood vessel dysfunction. This pilot study tests the hypothesis that unilateral resistance training of the leg extensors with partially restricted blood flow increases muscle strength and decreases vascular autoregulation...
March 2017: Journal of Pharmacopuncture
https://www.readbyqxmd.com/read/28388679/physical-activity-and-not-sedentary-time-per-se-influences-on-clustered-metabolic-risk-in-elderly-community-dwelling-women
#4
Andreas Nilsson, Britta Wåhlin-Larsson, Fawzi Kadi
INTRODUCTION: Whether amount of time spent in sedentary activities influences on clustered metabolic risk in elderly, and to what extent such an influence is independent of physical activity behavior, remain unclear. Therefore, the aim of the study was to examine cross-sectional associations of objectively assessed physical activity and sedentary behavior on metabolic risk outcomes in a sample of elderly community-dwelling women. METHODS: Metabolic risk outcomes including waist circumference, systolic and diastolic blood pressures, fasting levels of plasma glucose, HDL-cholesterol and triglycerides were assessed in 120 community-dwelling older women (65-70 yrs)...
2017: PloS One
https://www.readbyqxmd.com/read/28369670/effect-of-metabolic-syndrome-on-the-mobility-benefit-of-a-structured-physical-activity-intervention-the-lifestyle-interventions-and-independence-for-elders-randomized-clinical-trial
#5
Anda Botoseneanu, Haiying Chen, Walter T Ambrosius, Heather G Allore, Stephen Anton, Sara C Folta, Abby C King, Barbara J Nicklas, Bonnie J Spring, Elsa S Strotmeyer, Thomas M Gill
OBJECTIVES: To test whether structured physical activity (PA) is associated with a greater reduction in major mobility disability (MMD) in older persons with metabolic syndrome (MetS) than in those without. DESIGN: Data from the Lifestyle Interventions and Independence for Elders (LIFE) Study, a multicenter randomized trial of 1,635 persons with assessments every 6 months (average 2.7 years). SETTING: Eight U.S. centers. PARTICIPANTS: Sedentary men and women aged 70 to 89 with functional limitations (N = 1,535); 100 participants were excluded because of missing MetS data...
March 28, 2017: Journal of the American Geriatrics Society
https://www.readbyqxmd.com/read/28347337/the-effect-of-intervening-hospitalizations-on-the-benefit-of-structured-physical-activity-in-promoting-independent-mobility-among-community-living-older-persons-secondary-analysis-of-a-randomized-controlled-trial
#6
Thomas M Gill, Daniel P Beavers, Jack M Guralnik, Marco Pahor, Roger A Fielding, Michelle Hauser, Todd M Manini, Anthony P Marsh, Mary M McDermott, Anne B Newman, Heather G Allore, Michael E Miller
BACKGROUND: Among older persons, disability is often precipitated by intervening illnesses and injuries leading to hospitalization. In the Lifestyle Interventions and Independence for Elders (LIFE) Study, a structured moderate-intensity physical activity program, compared with a health education program, was shown to significantly reduce the amount of time spent with major mobility disability (MMD) over the course of 3.5 years. We aimed to determine whether the benefit of the physical activity program in promoting independent mobility was diminished in the setting of intervening hospitalizations...
March 28, 2017: BMC Medicine
https://www.readbyqxmd.com/read/28281730/cardiovascular-risk-reduction-in-sedentary-postmenopausal-women-during-organized-physical-activity
#7
Krzysztof Mazurek, Piotr Żmijewski, Ewa Kozdroń, Anna Fojt, Anna Czajkowska, Piotr Szczypiorski, Tomasz Mazurek
BACKGROUND: Cardiovascular (CV) diseases are the major cause of death in elderly women. Aerobic training (AT) improves component CV risk factors. Long-time higher-intensity group-based and home-based exercise training has been determined to improve exercise performance. However it is not clear if short-time group-based or home-based training with educational program permanently improves cardiometabolic parameters in elderly women. AIM: The aim of the study was to evaluate the effectiveness of organized physical activity programs dedicated to elderly, sedentary women...
March 10, 2017: Kardiologia Polska
https://www.readbyqxmd.com/read/28168689/effect-of-physical-activity-on-self-reported-disability-in-older-adults-results-from-the-life-study
#8
Todd M Manini, Daniel P Beavers, Marco Pahor, Jack M Guralnik, Bonnie Spring, Timothy S Church, Abby C King, Sara C Folta, Nancy W Glynn, Anthony P Marsh, Thomas M Gill
BACKGROUND/OBJECTIVES: To test the hypothesis that a long-term structured, moderate intensity physical activity (PA) program is more effective than a health education (HE) program in reducing the risk of s elf-reported dependency and disability in basic activities of daily living (BADLs), disability in instrumental ADLs (IADL), and mobility disability. DESIGN: The Lifestyle Interventions and Independence for Elders (LIFE) study was a multicenter, single-blinded randomized trial...
February 7, 2017: Journal of the American Geriatrics Society
https://www.readbyqxmd.com/read/27978491/validation-of-the-self-report-exernet-questionnaire-for-measuring-physical-activity-and-sedentary-behavior-in-elderly
#9
Christian López-Rodríguez, Maria Laguna, Alba Gómez-Cabello, Narcis Gusi, Luis Espino, Gerardo Villa, R Pedrero-Chamizo, J A Casajus, Ignacio Ara, Susana Aznar
This study aims to examine the validity and reliability of the Elderly EXERNET Physical Activity Questionnaire (EEPAQ) in a sample of Spanish elderly population. A sample of 73 elderly successfully completed the EEPAQ and wore an accelerometer over 7 consecutive days. Test-retest reliability of the EEPAQ was assessed by having the participants answer the EEPAQ twice within 14 days. Criterion validity was assessed for the questionnaire against the accelerometer, as the gold standard. Results indicated that EEPAQ had adequate reliability measured by Intraclass correlation coefficient (ICC) (walking ICC=0...
March 2017: Archives of Gerontology and Geriatrics
https://www.readbyqxmd.com/read/27969011/comparing-the-effects-of-music-and-exercise-with-music-for-older-adults-with-insomnia
#10
Chiung-Yu Huang, En-Ting Chang, Hui-Ling Lai
AIM: To examine the effects of a soothing music intervention before bedtime and a treadmill brisk walking exercise combined with music in the evening on sleep quality of sedentary older adults with chronic insomnia. BACKGROUND: There is evidence to support the use of complementary interventions to improve sleep. They are rarely applied in Taiwanese elderly population. METHODS: Using a crossover controlled trial, 38 participants aged 50 to 75 years were randomly assigned to a music intervention/brisk walking sequence or a brisk walking/music intervention sequence...
November 2016: Applied Nursing Research: ANR
https://www.readbyqxmd.com/read/27866841/thai-yoga-improves-physical-function-and-well-being-in-older-adults-a-randomised-controlled-trial
#11
Chaiya Noradechanunt, Anthony Worsley, Herbert Groeller
OBJECTIVES: Compare two 12-week low-intensity exercise regimens on components of physical function and quality of life in community-dwelling healthy yet sedentary adults aged over 60. DESIGN: This study used a randomised, multi-arm, controlled trial design. METHODS: Thirty-nine sedentary participants (29 women), aged 67.7±6.7 years were randomly allocated to either a 12-week Thai Yoga (TY) or Tai Chi (TC) for 90min twice per week, or telephone counselling Control (C)...
May 2017: Journal of Science and Medicine in Sport
https://www.readbyqxmd.com/read/27824693/aerobic-exercise-training-improves-orthostatic-tolerance-in-aging-humans
#12
Diqun Xu, Hong Wang, Shande Chen, Sarah Ross, Howe Liu, Albert Olivencia-Yurvati, Peter B Raven, Xiangrong Shi
PURPOSE: This study was designed to test the hypothesis that aerobic exercise training of the elderly will increase aerobic fitness without compromising orthostatic tolerance (OT). METHODS: Eight healthy sedentary volunteers (67.0 ± 1.7 yr old, four women) participated in 1 yr of endurance exercise training (stationary bicycle and/or treadmill) program at the individuals' 65%-75% of HRpeak. Peak O2 uptake (V˙O2peak) and HRpeak were determined by a maximal exercise stress test using a bicycle ergometer...
April 2017: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/27806005/effect-of-1-rm-80-rm-and-50-rm-strength-exercise-in-trained-individuals-on-variations-in-plasma-redox-biomarkers
#13
Tatiana G Polotow, Tácito P Souza-Junior, Ricardo C Sampaio, Alexandre R Okuyama, Douglas Ganini, Cristina V Vardaris, Ragami C Alves, Steven R McAnulty, Marcelo P Barros
For decades, scientists have examined the participation of oxygen/nitrogen species (ROS/RNS) in anaerobic-like exercises, especially weight lifting and resistance exercises. The balance between the production of oxyradicals and antioxidant responses during anaerobic-like exercises is essential to assure adaptation to the physiological benefits of strength training and to prevent chronic harmful effects. The aim of this study is to examine the hypothesis that different weight loads (1-RM, 80%RM, and 50%RM) lifted until exhaustion could impose distinct oxidative insults and elicit diverse antioxidant responses in plasma of young trained subjects...
October 27, 2016: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/27799413/factors-related-to-physical-activity-among-the-elderly-population-in-rural-thailand
#14
Plernta Ethisan, Ratana Somrongthong, Jamil Ahmed, Ramesh Kumar, Robert S Chapman
Physical activity in later years of life is not only essential to healthy aging and independent functioning, but it also helps prevent chronic diseases. We aimed this cross-sectional study to assess the prevalence of physical activity and associated factors among rural elderly Thais. We conducted this study on a sample of 300 elderly in 2 rural districts of Phranakornsiayutthaya province in Thailand. The mean age of participants were 67.5±6 years and 42% of them did not perform physical activity. Prevalence of vigorous and moderate intensity physical activity was 43...
April 2017: Journal of Primary Care & Community Health
https://www.readbyqxmd.com/read/27784297/correlates-of-sedentary-time-in-different-age-groups-results-from-a-large-cross-sectional-dutch-survey
#15
Claire M Bernaards, Vincent H Hildebrandt, Ingrid J M Hendriksen
BACKGROUND: Evidence shows that prolonged sitting is associated with an increased risk of mortality, independent of physical activity (PA). The aim of the study was to identify correlates of sedentary time (ST) in different age groups and day types (i.e. school-/work day versus non-school-/non-work day). METHODS: The study sample consisted of 1895 Dutch children (4-11 years), 1131 adolescents (12-17 years), 8003 adults (18-64 years) and 1569 elderly (65 years and older) who enrolled in the Dutch continuous national survey 'Injuries and Physical Activity in the Netherlands' between 2006 and 2011...
October 26, 2016: BMC Public Health
https://www.readbyqxmd.com/read/27746495/epidemiology-of-knee-osteoarthritis-in-india-and-related-factors
#16
Chandra Prakash Pal, Pulkesh Singh, Sanjay Chaturvedi, Kaushal Kumar Pruthi, Ashok Vij
BACKGROUND: Among the chronic rheumatic diseases, hip and knee osteoarthritis (OA) is the most prevalent and is a leading cause of pain and disability in most countries worldwide. Its prevalence increases with age and generally affects women more frequently than men. OA is strongly associated with aging and heavy physical occupational activity, a required livelihood for many people living in rural communities in developing countries. Determining region-specific OA prevalence and risk factor profiles will provide important information for planning future cost effective preventive strategies and health care services...
September 2016: Indian Journal of Orthopaedics
https://www.readbyqxmd.com/read/27734814/-the-impact-of-the-dosing-a-12-week-physical-training-on-the-concentration-of-nt-probnp-and-d-dimer-in-patients-with-heart-failure-and-impaired-functional-capacity-in-vii-x-decade-of-life
#17
Magdalena Andrzejczak-Karbowska, Robert Irzmański
Chronic heart failure (CHF), despite the preventive measures taken is the most common problem of modern cardiology. The aging of the body predisposes to the development of PNS, because qualitative changes taking place in the heart of the patient in the elderly are similar to those occurring among patients with heart failure. A growing problem of eldery patients becomes a deterioration of physical fitness leading to the reduction of activity and sedentary lifestyle. There is no doubt that increasing physical activity in the elderly should aim not only to restore the patient to a previous level of functioning, but also improve their physical resources to a higher level of efficiency and to facilitate independent functioning in everyday life...
July 29, 2016: Polski Merkuriusz Lekarski: Organ Polskiego Towarzystwa Lekarskiego
https://www.readbyqxmd.com/read/27687219/resistance-training-and-redox-homeostasis-correlation-with-age-associated-genomic-changes
#18
Ivan Dimauro, Mattia Scalabrin, Cristina Fantini, Elisa Grazioli, Maria Reyes Beltran Valls, Neri Mercatelli, Attilio Parisi, Stefania Sabatini, Luigi Di Luigi, Daniela Caporossi
Regular physical activity is effective as prevention and treatment for different chronic conditions related to the ageing processes. In fact, a sedentary lifestyle has been linked to a worsening of cellular ageing biomarkers such as telomere length (TL) and/or specific epigenetic changes (e.g. DNA methylation), with increase of the propensity to aging-related diseases and premature death. Extending our previous findings, we aimed to test the hypothesis that 12 weeks of low frequency, moderate intensity, explosive-type resistance training (EMRT) may attenuate age-associated genomic changes...
September 21, 2016: Redox Biology
https://www.readbyqxmd.com/read/27677093/hypothalamus-pituitary-adrenocortical-dysfunction-in-elderly-male-marathon-runners-feedback-sensitivity-stress-response-and-effects-on-verbal-memory
#19
Michael Deuschle, Ulrike Gotthardt, Ulrich Schweiger, Michael Dettling, Florian Holsboer, Isabella Heuser
Animal studies suggest that repeated episodes of elevated glucocorticoids lead to a dysregulation of the hypothalamus-pituitary-adrenal (HPA) system at a supra-pituitary level, and to impaired mnemonic function. We compared cognitive tests and both, feedback integrity and stress responsivity of the HPA system, between 11 elderly, male marathon runners - a model of repeated HPA system activation - and 10 sedentary controls. Marathon runners had significantly increased baseline, stress and post-stress ACTH, but not cortisol concentrations...
September 28, 2016: Neuroendocrinology
https://www.readbyqxmd.com/read/27676953/effects-of-brisk-walking-on-autonomic-nervous-system-reactivation-in-nursing-home-residents-additional-effects-of-transcutaneous-vagus-nerve-stimulation
#20
Jérémy Raffin, Jean-Claude Barthelemy, Philippe Terrat, Marie-Christine Diana, Emilie Achour, Paul Calmels, Mathieu Oriol, Thierry Busso, Lallia Hammadi, Claude Montuy-Coquard, Rémi Bouvier, Rémi Poillerat, Frédéric Roche, David Hupin
OBJECTIVE: It is well established that physical activity reduces the physiological effects of ageing. Among them, is the decrease of the autonomic nervous system (ANS) activity, which is associated with the increase of cardiovascular events and morbidities. It has been shown that high intensity cycle training can enhance the ANS activity by 30% in people with the age of 70. However, such trainings were done by old athletes, used to train at intensities that could not be tolerated by sedentary old people, such as nursing home residents...
September 2016: Annals of Physical and Rehabilitation Medicine
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