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https://www.readbyqxmd.com/read/29762540/the-role-of-peroxisome-proliferator-activated-receptors-and-their-transcriptional-coactivators-gene-variations-in-human-trainability-a-systematic-review
#1
REVIEW
Miroslav Petr, Petr Stastny, Adam Zajac, James J Tufano, Agnieszka Maciejewska-Skrendo
BACKGROUND: The peroxisome proliferator-activated receptors ( PPARA , PPARG , PPARD ) and their transcriptional coactivators' ( PPARGC1A , PPARGC1B ) gene polymorphisms have been associated with muscle morphology, oxygen uptake, power output and endurance performance. The purpose of this review is to determine whether the PPARs and/or their coactivators' polymorphisms can predict the training response to specific training stimuli. METHODS: In accordance with the Preferred Reporting Items for Systematic Reviews and Meta Analyses, a literature review has been run for a combination of PPARs and physical activity key words...
May 15, 2018: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/29725246/dehydroepiandrosterone-supplementation-combined-with-weight-loading-whole-body-vibration-training-wwbv-affects-exercise-performance-and-muscle-glycogen-storage-in-middle-aged-c57bl-6-mice
#2
Yi-Ming Chen, Hao-Chieh Lee, Mu-Tsung Chen, Chi-Chang Huang, Wen-Chyuan Chen
Background : Adequate nutritional intake and an optimal training program are important elements of any strategy to preserve or increase muscle mass and strength during aging. Purpose : In the current study, we investigate the effects of Dehydroepiandrosterone (DHEA), one of the most abundant circulating steroids in humans and a precursor hormone, supplementation combined with a weight-loading whole-body vibration (WWBV) on exercise performance, physical fatigue-related biochemical responses and testosterone content in middle-aged 9 months old C57BL/6 mice...
2018: International Journal of Medical Sciences
https://www.readbyqxmd.com/read/29719726/effect-of-short-and-long-moderate-intensity-exercises-in-modifying-cardiometabolic-markers-in-sedentary-kenyans-aged-50-years-and-above
#3
Karani Magutah, Rebecca Meiring, Nilesh B Patel, Kihumbu Thairu
Objectives: We compared effects of shorter moderate-intensity exercise time (<10 min bouts) on cardiometabolic parameters with the current recommendations among elderly adults. Methods: Fifty-three sedentary individuals aged ≥50 years were divided into exercise groups1: male and2 female short-duration bouts (MS and FS , respectively), and3 male and4 female long-duration bouts (ML and FL , respectively). Short-duration bouts consisted three 5-10 min moderate-intensity jogging sessions daily, and long-duration bouts consisted 30-60 min sessions 3-5 days weekly...
2018: BMJ Open Sport & Exercise Medicine
https://www.readbyqxmd.com/read/29696228/serious-adverse-events-of-older-adults-in-nursing-home-and-community-intervention-trials
#4
Rupak Datta, Mark Trentalange, Peter H Van Ness, Joanne M McGloin, Jack M Guralnik, Michael E Miller, Michael P Walkup, Neelesh Nadkarni, Marco Pahor, Thomas M Gill, Vincent Quagliarello, Manisha Juthani-Mehta
Background/Aims: Clinical trials of older adults are increasingly common, but risks of serious adverse events (SAE) may vary. We describe the incidence of SAE in two randomized trials, one community-based and one nursing home-based. Methods: We performed a secondary data analysis from two randomized clinical trials at one academic health center and 21 nursing homes involving 200 sedentary community dwellers aged 70-89 years and 185 female nursing home residents aged 65 years or older...
March 2018: Contemporary Clinical Trials Communications
https://www.readbyqxmd.com/read/29694591/-health-pain-and-daily-activities-among-elderly-people-practicing-lian-gong-and-sedentary-elderly-people
#5
Vanessa Cristina Dias Bobbo, Danilo Donizetti Trevisan, Maria Clara Estanislau do Amaral, Eliete Maria Silva
It is a well-known fact that the practice of physical activity on a regular basis among elderly people contributes to the prevention and reduction of pain, as well as promote active ageing. Based on this premise, the scope of this study was to evaluate the presence of chronic pain among elderly people attended in a primary health care unit in a city in the interior of Sao Paulo State, Brazil, by comparing those who practice Chinese gymnastics (Lian Gong) and the sedentary. Sixty elderly people were divided between 30 sedentary and 30 who participate in a group practicing Lian Gong...
April 2018: Ciência & Saúde Coletiva
https://www.readbyqxmd.com/read/29662923/effects-of-electrical-stimulation-on-skeletal-muscle-of-old-sedentary-people
#6
Simone Mosole, Sandra Zampieri, Sandra Furlan, Ugo Carraro, Stefan Löefler, Helmut Kern, Pompeo Volpe, Alessandra Nori
Physical activity plays an important role in preventing muscle atrophy and chronic diseases in adults and in the elderly. Calcium (Ca2+ ) cycling and activation of specific molecular pathways are essential in contraction-induced muscle adaptation. This study attains human muscle sections and total homogenates prepared from biopsies obtained before (control) and after 9 weeks of training by electrical stimulation (ES) on a group of volunteers. The aim of the study was to investigate about the molecular mechanisms that support functional muscle improvement by ES...
January 2018: Gerontology & Geriatric Medicine
https://www.readbyqxmd.com/read/29662308/hypoglycemic-and-antioxidant-effect-of-tai-chi-exercise-training-in-older-adults-with-metabolic-syndrome
#7
Víctor Manuel Mendoza-Núñez, Taide Laurita Arista-Ugalde, Juana Rosado-Pérez, Mirna Ruiz-Ramos, Edelmiro Santiago-Osorio
Introduction: The antioxidant and anti-inflammatory effects of Tai chi (TC) exercise training in healthy older adults has been demonstrated. However, there are no studies on this effect in older adults with metabolic syndrome (MetS). Purpose: The aim of this study was to determine the effect of TC exercise on oxidative stress and inflammatory markers in older adults with MetS. Methods: A quasi-experimental study was carried out with a sample of 110 older sedentary volunteers with clinical diagnoses of MetS: (i) a control group, n = 50, of individuals who do not participate in physical exercise, of which 37 fulfilled the entire study protocol, and (ii) an experimental group, n = 60, of subjects enrolled in a TC exercise training program (eight-form easy), 5 days a week for 6 months, in sessions of 50 min, under the supervision of a qualified instructor, of which 48 fulfilled the entire study protocol...
2018: Clinical Interventions in Aging
https://www.readbyqxmd.com/read/29659685/can-curcumin-counteract-cognitive-decline-clinical-trial-evidence-and-rationale-for-combining-%C3%AF-3-fatty-acids-with-curcumin
#8
Julia Christina Kuszewski, Rachel Heloise Xiwen Wong, Peter Ranald Charles Howe
The rate of cognitive decline in the elderly is highly variable. One potential factor contributing to accelerated cognitive decline is chronic systemic inflammation, because it has been linked to cognitive impairment and increased dementia risk. Certain lifestyle factors, such as excess body weight and sedentary behavior, can exacerbate a proinflammatory state in older adults, resulting in chronic low-grade inflammation. Supplementing the diet with curcumin, an anti-inflammatory polyphenolic compound from the curry spice turmeric, is a potential approach to prevent accelerated cognitive decline by counteracting chronic inflammatory processes...
March 1, 2018: Advances in Nutrition
https://www.readbyqxmd.com/read/29659622/the-association-of-single-and-combined-factors-of-sedentary-behavior-and-physical-activity-with-subjective-cognitive-complaints-among-community-dwelling-older-adults-cross-sectional-study
#9
Yuta Nemoto, Shinichiro Sato, Masaki Takahashi, Noriko Takeda, Munehiro Matsushita, Yoshinori Kitabatake, Kazushi Maruo, Takashi Arao
Subjective cognitive complaints (SCC) might be a meaningful indicator of dementia onset or mild cognitive impairment, and identifying the related factors of SCC could contribute to preventing these diseases. However, the relationship between SCC and lifestyle factors remains largely unproven. The purpose of this study was to examine the association of type of sedentary behavior, physical activity, or their combination with SCC among community-dwelling older adults. In 2016, 6677 community-living elderly were recruited to participate in a survey investigating cognition, physical activity, and sedentary behavior...
2018: PloS One
https://www.readbyqxmd.com/read/29608795/gait-speed-and-mobility-disability-revisiting-meaningful-levels-in-diverse-clinical-populations
#10
Michael E Miller, Jay Magaziner, Anthony P Marsh, Roger A Fielding, Thomas M Gill, Abby C King, Stephen Kritchevsky, Todd Manini, Mary M McDermott, Rebecca Neiberg, Denise Orwig, Adam J Santanasto, Marco Pahor, Jack Guralnik, W Jack Rejeski
OBJECTIVES: To investigate the heterogeneity of clinically meaningful levels of gait speed relative to self-reported mobility disability (SR-MD). DESIGN: Five longitudinal studies with older adults in different health states (onset of acute event, presence of chronic condition, sedentary, community living) were used to explore the relationship between gait speed and SR-MD. SETTING: Lifestyle Interventions and Independence for Elders Pilot (LIFE-P), LIFE, Trial of Angiotensin-Converting Enzyme Inhibition and Novel Cardiovascular Risk Factors (TRAIN), Baltimore Hip Fracture Study (BHS2), Invecchiare in Chianti (InCHIANTI)...
April 2, 2018: Journal of the American Geriatrics Society
https://www.readbyqxmd.com/read/29583015/effects-of-90-days-of-resveratrol-supplementation-on-cognitive-function-in-elders-a-pilot-study
#11
Stephen D Anton, Natalie Ebner, Joseph M Dzierzewski, Zvinka Z Zlatar, Matthew J Gurka, Vonetta M Dotson, Joshua Kirton, Robert T Mankowski, Michael Marsiske, Todd M Manini
OBJECTIVE: The purpose of this trial was to study the effects of chronic resveratrol use on cognitive function in humans. DESIGN: The authors conducted a double-blind, Phase IIa randomized, placebo-controlled trial to obtain preliminary estimates of the effects of resveratrol supplementation on cognitive function over a 90-day period in older adults. LOCATION: University of Florida in Gainesville, FL. SUBJECTS: Sedentary, overweight older adults (N = 32; age range: 65-93 years, M age = 73...
March 27, 2018: Journal of Alternative and Complementary Medicine: Research on Paradigm, Practice, and Policy
https://www.readbyqxmd.com/read/29582895/-feeling-more-self-confident-cheerful-and-safe-experiences-from-a-health-promoting-intervention-in-community-dwelling-older-adults-a-qualitative-study
#12
Å von Berens, A Koochek, M Nydahl, R A Fielding, T Gustafsson, D R Kirn, T Cederholm, M Södergren
OBJECTIVES: Studies show that regular exercise in combination with nutritional support can be effective in managing sarcopenia, which is age-related involuntary loss of skeletal muscle mass and strength. Qualitative investigations of participants' experiences from interventions in this domain are scarce. In this study, we explored older persons' experiences from an intervention designed to prevent sarcopenia, with the aim of capturing the participants' thoughts and opinions. DESIGN: A qualitative study embedded in the multicenter randomized clinical trial The Vitality and Vigor in the Elderly study, VIVE2...
2018: Journal of Nutrition, Health & Aging
https://www.readbyqxmd.com/read/29582714/the-impact-of-nordic-walking-training-on-the-gait-of-the-elderly
#13
Khaireddine Ben Mansour, Philippe Gorce, Nasser Rezzoug
The purpose of the current study was to define the impact of regular practice of Nordic walking on the gait of the elderly. Thereby, we aimed to determine whether the gait characteristics of active elderly persons practicing Nordic walking are more similar to healthy adults than that of the sedentary elderly. Comparison was made based on parameters computed from three inertial sensors during walking at a freely chosen velocity. Results showed differences in gait pattern in terms of the amplitude computed from acceleration and angular velocity at the lumbar region (root mean square), the distribution (Skewness) quantified from the vertical and Euclidean norm of the lumbar acceleration, the complexity (Sample Entropy) of the mediolateral component of lumbar angular velocity and the Euclidean norm of the shank acceleration and angular velocity, the regularity of the lower limbs, the spatiotemporal parameters and the variability (standard deviation) of stance and stride durations...
March 27, 2018: Journal of Sports Sciences
https://www.readbyqxmd.com/read/29563034/seasonality-of-physical-activity-sedentary-behavior-and-sleep-in-a-middle-aged-and-elderly-population-the-rotterdam-study
#14
Magda Cepeda, Chantal M Koolhaas, Frank J A van Rooij, Henning Tiemeier, Mònica Guxens, Oscar H Franco, Josje D Schoufour
INTRODUCTION: Physical activity (PA) and sedentary behavior (SB) have seasonal patterns. It remains unclear how these patterns are associated with sleep, meteorological factors, and health. METHODS: Activity levels were continuously measured with an accelerometer for seven days between July 2011 and May 2016, among middle-aged (50-64 years), young-elderly (65-74 years) and old-elderly (≥75 years) participants of a population-based Dutch cohort study (n = 1116)...
April 2018: Maturitas
https://www.readbyqxmd.com/read/29548971/ethnobotanical-survey-of-medicinal-plants-used-by-nomadic-peoples-in-the-algerian-steppe
#15
Mohamed Djamel Miara, Hamdi Bendif, Mohammed Ait Hammou, Irene Teixidor-Toneu
ETHNOPHARMACOLOGICAL RELEVANCE: This study is the first ethnobotanical survey focusing on the herbal medicines traditionally used by the nomadic community of the Algerian steppe, identifying new medicinal plants and uses from one of the most characteristic indigenous populations in Algeria. Moreover, the study contributes to the understanding of transmission of medicinal plant knowledge in the Mediterranean basin. AIM OF THE STUDY: This work aims to document the phytotherapeutical knowledge and practice of the nomadic community of the Algerian steppe, and compare it with neighbouring sedentary populations and Mediterranean historical texts...
March 13, 2018: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/29504059/influence-of-a-brisk-walking-program-on-postural-responses-in-sedentary-older-women-a-randomised-trial
#16
P L Bernard, H Blain, G Tallon, G Ninot, A Jaussent, M C Picot, C Belloc, O Coste, J Bousquet, S Ramdani
This study analyzes the evolution in kinematic and non-linear stabilometric parameters in elderly sedentary women selected to participate in a brisk walking program. Ninety-four women were randomly selected for a program of 78 sessions over 6 months, with three sessions of 60 min per week. On the force platform, participants were assessed with both eyes opened as well as eyes closed during a period of 51.2 s and the sampling frequency was 40 Hz. The main dependent kinematic variables were the length, stabilogram surface, and the mean position in anteroposterior as well as medio-lateral directions...
May 2018: Aging Clinical and Experimental Research
https://www.readbyqxmd.com/read/29480031/different-sickness-responses-in-adult-and-aged-rats-following-lipopolysaccharide-administration
#17
Barbara J Kupferschmid, Barbara Therrien, Pamela J Rowsey
OBJECTIVE: Immune challenges result in sickness responses such as decreased activity, fever, and spatial learning deficits. While these responses occur simultaneously, they are not usually evaluated concurrently or for an extended time. The purpose of this study was to examine how an immune challenge affected activity and temperature responses in animals tested concurrently in the Morris water maze (MWM) over 5 days and how aging interacts with such responses. METHOD: An accepted model of aging, adult ( n = 10; 5-6 months) and aged ( n = 7; 22 months) male Brown-Norway rats were implanted with a telemetry device (Mini Mitter, Oakmont, PA) to continuously monitor temperature and activity following an immune challenge...
May 2018: Biological Research for Nursing
https://www.readbyqxmd.com/read/29463192/home-based-exercise-for-elderly-patients-with-intermittent-claudication-limited-by-osteoarticular-disorders-feasibility-and-effectiveness-of-a-low-intensity-programme
#18
Nicola Lamberti, Sofia Straudi, Efisio Lissia, Lorenza Cavazzini, Sergio Buja, Roberto Manfredini, Nino Basaglia, Fabio Manfredini
BACKGROUND: Peripheral arterial disease (PAD) is a common cardiovascular pathology affecting mobility in elderly. Osteoarticular diseases (ODs), responsible for functional limitations and confounding leg symptoms, may interfere with exercise therapy. This study evaluates the feasibility and effectiveness of a structured home-based exercise programme on rehabilitative outcomes in a cohort of elderly PAD patients with and without coexisting ODs. PATIENTS AND METHODS: Patients were enrolled from 2002 to 2016 in an exercise programme prescribed and controlled at the hospital and based on two daily 10-minute home walking sessions below the self-selected speed...
April 2018: VASA. Zeitschrift Für Gefässkrankheiten
https://www.readbyqxmd.com/read/29384998/acute-hypotension-after-moderate-intensity-handgrip-exercise-in-hypertensive-elderly-people
#19
Luiz R Souza, Joyce B Vicente, Geiziane R Melo, Vivian C Moraes, Rafael R Olher, Iorrany C Sousa, Luiz H Peruchi, Rodrigo V Neves, Thiago S Rosa, Aparecido P Ferreira, Milton R Moraes
Isometric handgrip (IHG) training is effective in reducing blood pressure (BP), but little is known about the occurrence of acute hypotension by post-isometric exercise hypotension (PIEH) and the underlying mechanisms. Ten sedentary hypertensive elderly people (seven women and three men) individuals, with a mean age of 73.2±2.2 years and systolic BP (SBP) of 135.1±6.5, were included; they were hypertensive for 13.2±6.9 years and were receiving medications. These patients underwent two experimental sessions of isometric exercise using a portable hydraulic handgrip dynamometer: (i) sham session with 3% of maximal voluntary isometric contraction (MVIC) and (ii) experimental isometric session with 30% MVIC, completing a total of 8 sets of 1 min contraction and 1 min rest pause (overload of work = 51...
January 29, 2018: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/29383535/time-spent-outdoors-activity-levels-and-chronic-disease-among-american-adults
#20
Kirsten M M Beyer, Aniko Szabo, Kelly Hoormann, Melinda Stolley
Chronic diseases-including cancer, cardiovascular diseases, and metabolic conditions such as diabetes and obesity-account for over 60% of overall global mortality. Sedentary time increases the risk for chronic disease incidence and mortality, while moderate to vigorous physical activity is known to decrease risk. Most Americans spend at least half of their time sedentary, with a trend toward increasingly sedentary lifestyles, and few Americans achieve recommended levels of physical activity. Time spent outdoors has been associated with reduced sedentary time and increased physical activity among children/youth and the elderly, but few population-based studies have examined this relationship among working age adults who may face greater constraints on active, outdoor time...
January 30, 2018: Journal of Behavioral Medicine
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