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https://www.readbyqxmd.com/read/28090307/hemodynamic-response-to-treatment-of-iron-deficiency-anemia-in-pulmonary-arterial-hypertension-longitudinal-insights-from-an-implantable-hemodynamic-monitor
#1
Muddassir Mehmood, Richa Agarwal, Amresh Raina, Priscilla Correa-Jaque, Raymond L Benza
Despite new therapeutic options, pulmonary arterial hypertension (PAH) remains a progressive disease associated with substantial morbidity and mortality. As such, additional strategies for monitoring and adjunctive management of this disease are important. A 59-year-old woman with scleroderma-associated PAH received an implantable hemodynamic monitor (IHM) as part of a research protocol at our institution. Pulmonary artery pressures, heart rate, and cardiac output (sensor-based algorithm) were measured on a daily basis, and parameters of right ventricular (RV) performance and afterload were calculated...
December 2016: Pulmonary Circulation
https://www.readbyqxmd.com/read/28089759/using-pupil-size-and-heart-rate-to-infer-affective-states-during-behavioral-neurophysiology-and-neuropsychology-experiments
#2
Andrew R Mitz, Ravi V Chacko, Philip T Putnam, Peter H Rudebeck, Elisabeth A Murray
BACKGROUND: Nonhuman primates (NHPs) are a valuable research model because of their behavioral, physiological and neuroanatomical similarities to humans. In the absence of language, autonomic activity can provide crucial information about cognitive and affective states during single-unit recording, inactivation and lesion studies. Methods standardized for use in humans are not easily adapted to NHPs and detailed guidance has been lacking. NEW METHOD: We provide guidance for monitoring heart rate and pupil size in the behavioral neurophysiology setting by addressing the methodological issues, pitfalls and solutions for NHP studies...
January 12, 2017: Journal of Neuroscience Methods
https://www.readbyqxmd.com/read/28088956/-thoracic-paravertebral-block-in-the-pacu-for-immediate-postoperative-pain-relief-after-video-assisted-thoracoscopic-surgery
#3
F Liu, J Zhang, H K Zhang, Y Q Zhao, P Liang, Y X Zuo
Objective: To investigate the effectiveness and safety of the thoracic paravertebral block(TPVB) in the post postanesthesia care unit(PACU) for patients suffered moderate to severe pain after Video-Assisted Thoracoscopic Surgery(VATS). Methods: 78 atients who complained moderate to severe pain on arrival to PACU after VATS were randomly assigned into two groups: thoracic paravertebral block treatment group(P group) and sufentanil treatment group(S group). The VAS Pain score at rest and movement, heart rate, blood pressure, and pulse oximetry 1 hour after treatment and duration of patients staying in the PACU after treatment were recorded...
January 10, 2017: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/28087552/screening-for-atrial-fibrillation-using-economical-and-accurate-technology-safety-a-pilot-study
#4
Mark Lown, Arthur Yue, George Lewith, Paul Little, Mike Moore
INTRODUCTION: Atrial fibrillation (AF) is a cause of stroke and a marker of atherosclerosis and of all patients with stroke, around 17% have AF. The screening and treatment of AF could prevent about 12% of all strokes. Several relatively low-cost devices with good accuracy now exist which can detect AF including WatchBP and AliveCor. However, they can only measure the ECG or pulse over short time periods. Inexpensive devices such as heart rate monitors, which are widely available, can measure heart rate for prolonged periods and may have potential in screening for AF...
January 13, 2017: BMJ Open
https://www.readbyqxmd.com/read/28086943/a-lifestyle-intervention-among-elderly-men-on-active-surveillance-for-non-aggressive-prostate-cancer-a-randomised-feasibility-study-with-whole-grain-rye-and-exercise
#5
Anne Kirstine Eriksen, Rikke Dalgaard Hansen, Michael Borre, Ryan Godsk Larsen, Jeppe Munthe Jensen, Kristian Overgaard, Mette Borre, Cecilie Kyrø, Rikard Landberg, Anja Olsen, Anne Tjønneland
BACKGROUND: The prognosis for men with non-aggressive prostate cancer is good, and several studies have investigated the impact of lifestyle changes including physical activity and diet on the prognosis. Despite positive results in animal studies and a few human interventions with whole-grain rye on markers of prostate cancer progression, the feasibility of trials investigating such dietary changes in combination with physical activity remains largely unstudied. The primary aim was to investigate the feasibility of an intervention with high whole-grain rye intake and vigorous physical activity for 6 months in men diagnosed with prostate cancer...
January 13, 2017: Trials
https://www.readbyqxmd.com/read/28086882/differential-effects-of-glucagon-like-peptide-1-receptor-agonists-on-heart-rate
#6
REVIEW
Martin Lorenz, Francesca Lawson, David Owens, Denis Raccah, Christine Roy-Duval, Anne Lehmann, Riccardo Perfetti, Lawrence Blonde
While glucagon-like peptide-1 receptor agonists (GLP-1 RAs) are known to increase heart rate (HR), it is insufficiently recognized that the extent varies greatly between the various agonists and is affected by the assessment methods employed. Here we review published data from 24-h time-averaged HR monitoring in healthy individuals and subjects with type 2 diabetes mellitus (T2DM) treated with either short-acting GLP-1 RAs, lixisenatide or exenatide, or long-acting GLP-1 RAs, exenatide LAR, liraglutide, albiglutide, or dulaglutide (N = 1112; active-treatment arms)...
January 13, 2017: Cardiovascular Diabetology
https://www.readbyqxmd.com/read/28081306/tracheal-intubation-in-patients-immobilized-by-a-rigid-collar-a-comparison-of-glidescope-and-an-intubating-laryngeal-mask-airway
#7
Semih Özdil, Zehra İpek Arslan Aydın, Zehra Nur Baykara, Kamil Toker, Zeynep Mine Solak
BACKGROUND/AIM: Intubation must be rapidly performed with the utmost care in cervical trauma patients. We present the first comparison of GlideScope and an intubating laryngeal mask airway (ILMA) regarding insertion and intubation times, intubation success rates, mucosal damage, need for optimization maneuvers, effects on hemodynamic changes, and postoperative minor complications in a simulated cervical injury with a Philadelphia cervical collar. MATERIALS AND METHODS: Ethics committee approval and patient consent were obtained and 94 American Society of Anesthesiology physical status I or II patients were enrolled in this study...
December 20, 2016: Turkish Journal of Medical Sciences
https://www.readbyqxmd.com/read/28080048/wearable-sensors-for-personal-monitoring-and-estimation-of-inhaled-traffic-related-air-pollution-evaluation-of-methods
#8
Evi Dons, Michelle Laeremans, Juan Pablo Orjuela, Ione Avila-Palencia, Glòria Carrasco-Turigas, Tom Cole-Hunter, Esther Anaya-Boig, Arnout Standaert, Patrick De Boever, Tim S Nawrot, Thomas Götschi, Audrey de Nazelle, Mark J Nieuwenhuijsen, Luc Int Panis
Physical activity and ventilation rates have an effect on an individual's dose and may be important to consider in exposure-response relationships; however, these factors are often ignored in environmental epidemiology studies. The aim of this study was to evaluate methods to estimate the inhaled dose of air pollution and understand variability, in the absence of a true gold standard metric. Five types of methods were identified: (1) methods using (physical) activity types; (2) methods based on energy expenditure, METs (metabolic equivalents of task) and oxygen consumption; (3) methods based on heart rate or (4) breathing rate; and (5) methods that combine heart and breathing rate...
January 12, 2017: Environmental Science & Technology
https://www.readbyqxmd.com/read/28077904/regadenoson-in-myocardial-perfusion-study-first-institutional-experiences-in-bosnia-and-herzegovina
#9
Nermina Beslic, Renata Milardovic, Amera Sadija, Sejla Ceric, Zeljka Raic
INTRODUCTION: Myocardial perfusion imaging (MPI) is widely used in the evaluation of known and suspected coronary artery disease (CAD). Imaging of heart in stress and rest enables the comparison of myocardial uptake of radiotracer in proportion to the needs and coronary flow, which is used for detection of perfusion defects. Exercise stress and pharmacologic agents are used for the stressing purpose. Novel pharmacologic stressor regadenoson is A2A selective adenosine agonist, which selectively binds to the adenosine receptors in coronary arteries causing coronary dilatation...
December 2016: Acta Informatica Medica: AIM
https://www.readbyqxmd.com/read/28075341/a-non-invasive-multichannel-hybrid-fiber-optic-sensor-system-for-vital-sign-monitoring
#10
Marcel Fajkus, Jan Nedoma, Radek Martinek, Vladimir Vasinek, Homer Nazeran, Petr Siska
In this article, we briefly describe the design, construction, and functional verification of a hybrid multichannel fiber-optic sensor system for basic vital sign monitoring. This sensor uses a novel non-invasive measurement probe based on the fiber Bragg grating (FBG). The probe is composed of two FBGs encapsulated inside a polydimethylsiloxane polymer (PDMS). The PDMS is non-reactive to human skin and resistant to electromagnetic waves, UV absorption, and radiation. We emphasize the construction of the probe to be specifically used for basic vital sign monitoring such as body temperature, respiratory rate and heart rate...
January 8, 2017: Sensors
https://www.readbyqxmd.com/read/28075064/efficacy-of-nebivolol-valsartan-single-pill-combination-in-obese-and-nonobese-patients-with-hypertension
#11
Christian W Mende, Thomas D Giles, David B Bharucha, William G Ferguson, Madhuja Mallick, Mehul D Patel
Antihypertensive efficacy of single-pill combinations (SPCs) consisting of a β1 -selective adrenergic blocker with vasodilatory properties via β3 -agonism (nebivolol) and an angiotensin II receptor blocker (valsartan) was demonstrated in an 8-week phase 3 trial (NCT01508026). In this post hoc analysis, seated blood pressure, heart rate, 24-hour ambulatory blood pressure monitoring, plasma aldosterone, estimated glomerular filtration rate, and safety measures were assessed in obese (body mass index >32 kg/m(2) ; n=1823) and nonobese (body mass index <27 kg/m(2) ; n=847) adults with hypertension (stage I or II) treated with nebivolol-valsartan SPCs, nebivolol or valsartan monotherapy, or placebo...
January 11, 2017: Journal of Clinical Hypertension
https://www.readbyqxmd.com/read/28074275/crossover-assessment-of-cardiolocomotor-synchronization-during-running
#12
Lucenildo Silva Cerqueira, Aluizio D'Affonsêca Netto, Roger Gomes Tavares Mello, Jurandir Nadal
PURPOSE: This study aimed at testing the hypothesis that positive cardiolocomotor coordination (CLC) measure occurs by chance during a running task where the heart rate (HR) is approximated to the step frequency (StepF). METHODS: The electrocardiogram and electromyogram from the right gastrocnemius lateralis muscle were continuously recorded from ten healthy young men running at a paced rhythm of 152 step/min, to monitor HR and StepF. CLC was evaluated by phase synchrograms and the index of conditional probability (iCP)...
January 10, 2017: European Journal of Applied Physiology
https://www.readbyqxmd.com/read/28073850/characterization-of-mineralocorticoid-receptor-antagonist-therapy-initiation-in-high-risk-patients-with-heart-failure
#13
Lauren B Cooper, Bradley G Hammill, Eric D Peterson, Bertram Pitt, Matthew L Maciejewski, Lesley H Curtis, Adrian F Hernandez
BACKGROUND: Heart failure guidelines recommend routine monitoring of serum potassium, and renal function in patients treated with a mineralocorticoid receptor antagonist (MRA). How these recommendations are implemented in high-risk patients or according to setting of drug initiation is poorly characterized. METHODS AND RESULTS: We conducted a retrospective cohort study of Medicare beneficiaries linked to laboratory data in 10 states with prevalent heart failure as of July 1, 2011, and incident MRA use between May 1 and September 30, 2011...
January 2017: Circulation. Cardiovascular Quality and Outcomes
https://www.readbyqxmd.com/read/28072689/an-observational-study-on-the-effect-of-premature-ventricular-complex-burden-on-long-term-outcome
#14
Chin-Yu Lin, Shih-Lin Chang, Yenn-Jiang Lin, Yun-Yu Chen, Li-Wei Lo, Yu-Feng Hu, Ta-Chuan Tuan, Tze-Fan Chao, Fa-Po Chung, Jo-Nan Liao, Yao-Ting Chang, Chung-Hsing Lin, Rohit Walia, Abigail Louise D Te, Shinya Yamada, Chuen-Wang Chiou, Hsuan-Ming Tsao, Shih-Ann Chen
The long-term clinical impact of premature ventricular complexes (PVCs) on mortality and morbidity has not been fully studied. This study aimed to investigate the association between the burden of PVCs and adverse clinical outcome.A total of 5778 subjects, who were pacemaker-free and ventricular tachycardia-free at baseline, received 24-hour electrocardiography monitoring between January 1, 2002 and December 31, 2004. Clinical event data were retrieved from the Bureau of National Health Insurance of Taiwan...
January 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28071133/effect-of-transcutaneous-acupoint-electrical-stimulation-on-post-hemorrhoidectomy-associated-pain-anxiety-and-heart-rate-variability
#15
Mei-Ling Yeh, Yu-Chu Chung, Lun-Chia Hsu, Shuo-Hui Hung
Hemorrhoidectomy is the current best treatment for severe hemorrhoids, but it causes significant postoperative pain and anxiety, which is associated with heart rate variability (HRV). Transcutaneous acupoint electrical stimulation (TAES) was assumed to alleviate pain and anxiety, and modify the autonomic nervous system. This study aimed to examine the effects of TAES intervention on postoperative pain, anxiety, and HRV in patients who received a hemorrhoidectomy. A randomized-controlled trial with five repeated measures was conducted...
January 1, 2017: Clinical Nursing Research
https://www.readbyqxmd.com/read/28069511/in-vivo-characterization-of-magnesium-alloy-biodegradation-using-electrochemical-h2-monitoring-icp-ms-and-xps
#16
Daoli Zhao, Tingting Wang, Keaton Nahan, Xuefei Guo, Zhanping Zhang, Zhongyun Dong, Shuna Chen, Da-Tren Chou, Daeho Hong, Prashant N Kumta, William R Heineman
: The effect of widely different corrosion rates of Mg alloys on four parameters of interest for in vivo characterization was evaluated: (1) the effectiveness of transdermal H2 measurements with an electrochemical sensor for noninvasively monitoring biodegradation compared to the standard techniques of in vivo X-ray imaging and weight loss measurement of explanted samples, (2) the chemical compositions of the corrosion layers of the explanted samples by XPS, (3) the effect on animal organs by histology, and (4) the accumulation of corrosion by-products in multiple organs by ICP-MS...
January 6, 2017: Acta Biomaterialia
https://www.readbyqxmd.com/read/28067212/estimation-of-the-qt-rr-relation-trade-off-between-goodness-of-fit-and-extrapolation-accuracy
#17
Alain Vinet, Bruno Dubé, Réginald Nadeau, Omar Mahiddine, Vincent Jacquemet
Correction of the QT interval in the ECG for changes in heart rate (RR interval) is needed to compare groups of patients and assess the risk of sudden cardiac death. The QTc represents the QT interval at 60 bpm, although most patients typically have a faster heart rate, thus requiring extrapolation of the QT-RR relationship. This paper investigates the ability of QT-RR models with increasing number of parameters to fit beat-to-beat variations in the QT interval and provide a reliable estimate of the QTc. One-, two- and three-parameter functions generalising the Bazett and Fridericia formulas were used in combination with hysteresis reduction (memory) obtained by time-averaging the history of RR intervals with exponentially-decaying weights...
January 9, 2017: Physiological Measurement
https://www.readbyqxmd.com/read/28062865/-poor-outcome-factors-associated-to-patients-with-lower-digestive-bleeding-in-a-public-hospital
#18
Jorge Luis Rojas-Domínguez, Alvaro Carvallo-Michelena, Alejandro Piscoya, Edson Guzmán
BACKGROUND: Lower gastrointestinal bleeding (LGIB) is an event that has shown an increase in complications and mortality rates in the last decades. Although some factors associated with poor outcome have been identified, there are several yet to be evaluated. OBJECTIVE: To identify risk factors for poor outcome in patients with LGIB in the Hospital Edgardo Rebagliati Martins of Lima, Peru. MATERIAL AND METHODS: A prospective analytic observational cohort study was made, and a census was conducted with all patients with acute LGIB between January 2010 and December 2013...
October 2016: Revista de Gastroenterología del Perú: órgano Oficial de la Sociedad de Gastroenterología del Perú
https://www.readbyqxmd.com/read/28060219/multicenter-study-of-adverse-events-after-intravenous-tissue-type-plasminogen-activator-treatment-of-acute-ischemic-stroke
#19
Hannah Fernandez-Gotico, Tiffany Lightfoot, Melissa Meighan
BACKGROUND AND PURPOSE: The approved treatment by the Food and Drug Administration for acute ischemic stroke is intravenous tissue-type plasminogen activator (IV tPA). After IV tPA administration, patients are monitored for adverse events using an American Heart Association/American Stroke Association guideline instituted in 1996. There is limited evidence describing the safest and most efficient method to monitor patients during the first 24 hours after tPA administration. Although the overall rates of adverse events have been reported, the time when patients may be at most risk for an event has not been studied...
February 2017: Journal of Neuroscience Nursing: Journal of the American Association of Neuroscience Nurses
https://www.readbyqxmd.com/read/28055987/heart-beat-classification-from-single-lead-ecg-using-the-synchrosqueezing-transform
#20
Christophe L Herry, Martin Frasch, Andrew Je Seely, Hau-Tieng Wu
The processing of ECG signal provides a wealth of information on cardiac function and overall cardiovascular health. While multi-lead ECG recordings are often necessary for a proper assessment of cardiac rhythms, they are not always available or practical, for example in fetal ECG applications. Moreover, a wide range of small non-obtrusive single-lead ECG ambulatory monitoring devices are now available, from which heart rate variability (HRV) and other health-related metrics are derived. Proper beat detection and classification of abnormal rhythms is important for reliable HRV assessment and can be challenging in single-lead ECG monitoring devices...
January 5, 2017: Physiological Measurement
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