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https://www.readbyqxmd.com/read/29453755/effect-of-nicotine-on-repeated-bouts-of-anaerobic-exercise-in-nicotine-na%C3%A3-ve-individuals
#1
Robert Johnston, Melissa Crowe, Kenji Doma
PURPOSE: Nicotine is a psychostimulant that is reported to be commonly supplemented by athletes. The purpose of the current study was to determine the effects of a rapidly absorbed form of nicotine on repeated bouts of anaerobic exercise, perception of exertion and a range of cardiovascular variables while monitoring side effect profiles. METHODS: Sixteen healthy, nicotine naïve male athletes (24.1 ± 5.3 years, 179.0 ± 8.8 cm, 81.7 ± 13.5 kg, BMI 25.5 ± 3.0, Body fat% 13...
February 16, 2018: European Journal of Applied Physiology
https://www.readbyqxmd.com/read/29452687/diagnostic-challenges-in-epilepsy-seizure-under-reporting-and-seizure-detection
#2
REVIEW
Christian E Elger, Christian Hoppe
Epileptic seizures vary greatly in clinical phenomenology and can markedly affect the patient's quality of life. As therapeutic interventions focus on reduction or elimination of seizures, the accurate documentation of seizure occurrence is essential. However, patient self-evaluation compared with objective evaluation by video-electroencephalography (EEG) monitoring or long-term ambulatory EEG revealed that patients document fewer than 50% of their seizures, on average, and that documentation accuracy varies significantly over time...
March 2018: Lancet Neurology
https://www.readbyqxmd.com/read/29452603/the-effects-of-desflurane-and-sevoflurane-on-nesfatin-1-levels-in-laparoscopic-cholecystectomy-a-randomized-controlled-trial
#3
A T D Ozcan, C B Altin, S Erdogan, M Ergin, A Çiftçi, H Kara, S M Aksoy, A But
BACKGROUND: Nesfatin-1 is involved in cardiovascular regulation, stress-related responses. The objective of this study is to investigate the impact of volatile anesthetics on Nesfatin-1 levels. METHOD: Fourty-two patients aged 30-65 years with the American Society Anesthesiology (ASA) Class I-II who were scheduled for laparoscopic cholecystectomy were included in the study Patients were randomized into two group; desflurane administered group (Group I, n = 21) and sevoflurane administered group (Group II, n = 21)...
February 16, 2018: BMC Anesthesiology
https://www.readbyqxmd.com/read/29451048/impact-of-radon-and-combinatory-radon-carbon-dioxide-spa-on-pain-and-hypertension-results-from-the-explorative-rad-on01-study
#4
Paul F Rühle, Gerhart Klein, Tatjana Rung, Hong Tiep Phan, Claudia Fournier, Rainer Fietkau, Udo S Gaipl, Benjamin Frey
OBJECTIVES: Therapies with low doses of radon have beneficial effects on patients suffering from chronic painful degenerative and inflammatory diseases. We already showed that this is accompanied by systemic immune modulations. We here focus on pain reducing effects of very low doses of radon by adding carbon dioxide water and its impact on heart rate variability (HRV), blood pressure and free radicals. METHODS: 100 patients receiving radon spa (1.200 Bq/l at 34°C or 600 Bq/l, 1 g/l CO 2 at 34°C) were monitored before and at three different time points after therapy...
February 16, 2018: Modern Rheumatology
https://www.readbyqxmd.com/read/29450689/the-first-multicenter-randomized-controlled-trial-of-home-telemonitoring-for-japanese-patients-with-heart-failure-home-telemonitoring-study-for-patients-with-heart-failure-homes-hf
#5
Norihiko Kotooka, Masafumi Kitakaze, Kengo Nagashima, Machiko Asaka, Yoshiharu Kinugasa, Kotaro Nochioka, Atsushi Mizuno, Daisuke Nagatomo, Daigo Mine, Yoko Yamada, Akiko Kuratomi, Norihiro Okada, Daisuke Fujimatsu, So Kuwahata, Shigeru Toyoda, Shin-Ichi Hirotani, Takahiro Komori, Kazuo Eguchi, Kazuomi Kario, Takayuki Inomata, Kaoru Sugi, Kazuhiro Yamamoto, Hiroyuki Tsutsui, Tohru Masuyama, Hiroaki Shimokawa, Shin-Ichi Momomura, Yoshihiko Seino, Yasunori Sato, Teruo Inoue, Koichi Node
Home telemonitoring is becoming more important to home medical care for patients with heart failure. Since there are no data on home telemonitoring for Japanese patients with heart failure, we investigated its effect on cardiovascular outcomes. The HOMES-HF study was the first multicenter, open-label, randomized, controlled trial (RCT) to elucidate the effectiveness of home telemonitoring of physiological data, such as body weight, blood pressure, and pulse rate, for Japanese patients with heart failure (UMIN Clinical Trials Registry 000006839)...
February 15, 2018: Heart and Vessels
https://www.readbyqxmd.com/read/29449338/status-of-hypertension-in-china-results-from-the-china-hypertension-survey-2012-2015
#6
Zengwu Wang, Zuo Chen, Linfeng Zhang, Xin Wang, Guang Hao, Zugui Zhang, Lan Shao, Ye Tian, Ying Dong, Congyi Zheng, Jiali Wang, Manlu Zhu, William S Weintraub, Runlin Gao
Background -Although the prevalence of hypertension (HTN) continues to increase in developing countries including China, recent data are lacking. A national wide survey was conducted from October 2012 to December 2015 to assess the prevalence of HTN in China. Methods -A stratified multistage random sampling method was used to obtain a nationally representative sample of 451,755 residents aged ≥18 years from 31 provinces in mainland China from October 2012 to December 2015. Blood pressure (BP) was measured after resting for 5 minutes by trained staff, using a validated oscillometric BP monitor...
February 15, 2018: Circulation
https://www.readbyqxmd.com/read/29448876/evaluation-of-injectable-anaesthesia-with-five-medetomidine-midazolam-based-combinations-in-egyptian-fruit-bats-rousettus-aegyptiacus
#7
Avishag Tuval, Liora Las, Yael Shilo-Benjamini
Egyptian fruit bats are increasingly used as model animals in neuroscience research. Our aim was to characterize suitable injectable anaesthesia for this species, possibly replacing inhalant anaesthesia, thus minimizing occupational health hazards. Eight bats were randomly assigned by a crossover design for subcutaneously administered combinations of medetomidine-midazolam with: saline (MM-Sal), ketamine (MM-Ket), fentanyl (MM-Fen), morphine (MM-Mor), or butorphanol (MM-But). The anaesthetic depth and vital signs were monitored at baseline and every 10 min until bats recovered...
January 1, 2018: Laboratory Animals
https://www.readbyqxmd.com/read/29447399/the-relationship-between-soldier-performance-on-the-two-mile-run-and-the-20-m-shuttle-run-test
#8
Maria C Canino, Bruce S Cohen, Jan E Redmond, Marilyn A Sharp, Edward J Zambraski, Stephen A Foulis
Background: The 20-m shuttle run test (MSRT) is a common field test used to measure aerobic fitness in controlled environments. The U.S. Army currently assesses aerobic fitness with the two-mile run (TMR), but external factors may impact test performance. The aim of this study is to examine the relationship between the Army Physical Fitness Test TMR performance and the MSRT in military personnel. Methods: A group of 531 (403 males and 128 females) active duty soldiers (age: 24...
February 13, 2018: Military Medicine
https://www.readbyqxmd.com/read/29447081/is-neuropathic-pain-associated-with-cardiac-sympathovagal-activity-changes-in-patients-with-breast-cancer
#9
Hilal Yesil, Sibel Eyigor, Meral Kayıkcıoglu, Ruchan Uslu, Menekse Inbat, Benay Ozbay
Objective Heart rate variability (HRV) is a good indicator of the autonomic nervous system (ANS) activity. A few studies have been conducted recently and have shown a relationship between reduced HRV and conditions that lead to neuropathic pain (NP). In this study, we aimed to investigate whether NP is associated with changes in cardiac sympathovagal activity in patients with breast cancer (BC). Methods We used the Leeds Assessment of Neuropathic Symptoms and Signs (LANSS) questionnaire to evaluate NP in 70 patients with BC...
February 15, 2018: Neurological Research
https://www.readbyqxmd.com/read/29444097/the-effects-of-intensified-training-on-resting-metabolic-rate-rmr-body-composition-and-performance-in-trained-cyclists
#10
Amy L Woods, Anthony J Rice, Laura A Garvican-Lewis, Alice M Wallett, Bronwen Lundy, Margot A Rogers, Marijke Welvaert, Shona Halson, Andrew McKune, Kevin G Thompson
BACKGROUND: Recent research has demonstrated decreases in resting metabolic rate (RMR), body composition and performance following a period of intensified training in elite athletes, however the underlying mechanisms of change remain unclear. Therefore, the aim of the present study was to investigate how an intensified training period, designed to elicit overreaching, affects RMR, body composition, and performance in trained endurance athletes, and to elucidate underlying mechanisms. METHOD: Thirteen (n = 13) trained male cyclists completed a six-week training program consisting of a "Baseline" week (100% of regular training load), a "Build" week (~120% of Baseline load), two "Loading" weeks (~140, 150% of Baseline load, respectively) and two "Recovery" weeks (~80% of Baseline load)...
2018: PloS One
https://www.readbyqxmd.com/read/29443088/simultaneous-video-eeg-ecg-monitoring-to-identify-neurocardiac-dysfunction-in-mouse-models-of-epilepsy
#11
Vikas Mishra, Nicole M Gautier, Edward Glasscock
In epilepsy, seizures can evoke cardiac rhythm disturbances such as heart rate changes, conduction blocks, asystoles, and arrhythmias, which can potentially increase risk of sudden unexpected death in epilepsy (SUDEP). Electroencephalography (EEG) and electrocardiography (ECG) are widely used clinical diagnostic tools to monitor for abnormal brain and cardiac rhythms in patients. Here, a technique to simultaneously record video, EEG, and ECG in mice to measure behavior, brain, and cardiac activities, respectively, is described...
January 29, 2018: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/29443059/in-vivo-electrophysiological-measurement-of-the-rat-ulnar-nerve-with-axonal-excitability-testing
#12
Brandon M Wild, Renée Morris, Mihai Moldovan, Christian Krarup, Arun V Krishnan, Ria Arnold
Electrophysiology enables the objective assessment of peripheral nerve function in vivo. Traditional nerve conduction measures such as amplitude and latency detect chronic axon loss and demyelination, respectively. Axonal excitability techniques "by threshold tracking" expand upon these measures by providing information regarding the activity of ion channels, pumps and exchangers that relate to acute function and may precede degenerative events. As such, the use of axonal excitability in animal models of neurological disorders may provide a useful in vivo measure to assess novel therapeutic interventions...
February 6, 2018: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/29442057/inguinal-hernia-repair-in-day-surgery-the-role-of-mac-monitored-anesthesia-care-with-remifentanil
#13
P Palumbo, S Usai, C Amatucci, B Perotti, L Ruggeri, G Illuminati, G Tellan
BACKGROUND: The extension of indications for procedures in a Day Surgery (DS) setting has led to changes in the anesthetic and surgical treatment of Inguinal Hernias (IH). According to the recommendations of the European Hernia Society, the treatment of IH in DS units should be performed under Monitored Anesthesia Care (MAC). PATIENTS AND METHODS: 960 patients underwent IH repairs over a period of 24 months. The patients were randomly divided into two groups: R (remifentanil) and F (fentanyl); the group F was considered as a control group...
November 2017: Il Giornale di Chirurgia
https://www.readbyqxmd.com/read/29437032/computerised-interpretation-of-the-fetal-heart-rate-during-labour-a-randomised-controlled-trial-infant
#14
Peter Brocklehurst, David Field, Keith Greene, Edmund Juszczak, Sara Kenyon, Louise Linsell, Chris Mabey, Mary Newburn, Rachel Plachcinski, Maria Quigley, Philip Steer, Liz Schroeder, Oliver Rivero-Arias
BACKGROUND: Continuous electronic fetal monitoring (EFM) in labour is widely used and computerised interpretation has the potential to increase its utility. OBJECTIVES: This trial aimed to find out whether or not the addition of decision support software to assist in the interpretation of the cardiotocograph (CTG) reduced the number of poor neonatal outcomes, and whether or not it was cost-effective. DESIGN: Two-arm individually randomised controlled trial...
February 2018: Health Technology Assessment: HTA
https://www.readbyqxmd.com/read/29433969/shift-work-is-associated-with-reduced-heart-rate-variability-among-men-but-not-women
#15
Gerben Hulsegge, Nidhi Gupta, Karin I Proper, Natasja van Lobenstein, Wilhelmina IJzelenberg, David M Hallman, Andreas Holtermann, Allard J van der Beek
BACKGROUND: Imbalance in the autonomic nervous system due to a disrupted circadian rhythm may be a cause of shift work-related cardiovascular diseases. OBJECTIVE: We aimed to determine the association between shift work and cardiac autonomic activity in blue-collar workers. METHODS: The study included 665 blue-collar workers aged 18-68 years in different occupations from two Danish cohort studies. Time and frequency domain parameters of heart rate variability (HRV) were measured during sleep using the Actiheart monitor, and used as markers of cardiac autonomic function...
February 9, 2018: International Journal of Cardiology
https://www.readbyqxmd.com/read/29428337/relationship-between-diabetes-mellitus-and-heart-rate-variability-in-community-dwelling-elders
#16
Ícaro J S Ribeiro, Rafael Pereira, Paulo F Valença Neto, Ivna V Freire, Cezar A Casotti, Mitermayer Galvão Dos Reis
BACKGROUND AND OBJECTIVE: Diabetes mellitus is one of the most common non-communicable diseases (NCDs) and may influence the autonomic nervous system. This study aims to analyze the autonomic control, through heart rate variability (HRV), from community-dwelling elders with (DM+) and without diabetes mellitus (DM-). MATERIALS AND METHODS: This cross-sectional study, in which 205 elders (≥ 60 years old), from the urban area of Aiquara municipality gave their written consent to participate...
February 3, 2018: Medicina
https://www.readbyqxmd.com/read/29425167/-i-was-relieved-to-know-that-my-baby-was-safe-women-s-attitudes-and-perceptions-on-using-a-new-electronic-fetal-heart-rate-monitor-during-labor-in-tanzania
#17
Sara Rivenes Lafontan, Johanne Sundby, Hege L Ersdal, Muzdalifat Abeid, Hussein L Kidanto, Columba K Mbekenga
To increase labor monitoring and prevent neonatal morbidity and mortality, a new wireless, strap-on electronic fetal heart rate monitor called Moyo was introduced in Tanzania in 2016. As part of the ongoing evaluation of the introduction of the monitor, the aim of this study was to explore the attitudes and perceptions of women who had worn the monitor continuously during their most recent delivery and perceptions about how it affected care. This knowledge is important to identify barriers towards adaptation in order to introduce new technology more effectively...
February 9, 2018: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/29422211/outcome-in-early-onset-fetal-growth-restriction-is%C3%A2-best-combining-computerized-fetal-heart-rate-analysis-with-ductus-venosus-doppler-insights-from-the-trial-of-umbilical-and-fetal-flow-in-europe
#18
REVIEW
Tiziana Frusca, Tullia Todros, Christoph Lees, Caterina M Bilardo
BACKGROUND: Early-onset fetal growth restriction represents a particular dilemma in clinical management balancing the risk of iatrogenic prematurity with waiting for the fetus to gain more maturity, while being exposed to the risk of intrauterine death or the sequelae of acidosis. OBJECTIVE: The Trial of Umbilical and Fetal Flow in Europe was a European, multicenter, randomized trial aimed to determine according to which criteria delivery should be triggered in early fetal growth restriction...
February 2018: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/29421914/the-safety-of-deep-sedation-with-propofol-controlled-by-the-endoscopist-in-endoscopic-retrograde-cholangiopancreatography-ercp-a-prospective-study-in-a-tertiary-hospital
#19
Lara Luzón Solanas, Leticia Ollero Domenche, Eva María Sierra Moros, José Val Pérez, María Teresa Soria San Teodoro, Teresa Giménez Júlvez, Rafael Uribarrena Amezaga
INTRODUCTION: propofol administered by an endoscopist with a trained nurse has evolved as an alternative to anesthesia monitoring and is increasingly common in the routine clinical practice, even in advanced endoscopy. OBJECTIVE: to evaluate the safety of deep sedation with endoscopist-controlled propofol in patients undergoing endoscopic retrograde cholangiopancreatography (ERCP). MATERIAL AND METHODS: this was a prospective study in patients undergoing ERCP under deep sedation with propofol...
February 9, 2018: Revista Española de Enfermedades Digestivas
https://www.readbyqxmd.com/read/29420394/second-stage-duration-and-outcomes-among-women-who-labored-after-a-prior-cesarean-delivery
#20
Mark P Hehir, Dwight J Rouse, Russell S Miller, Cande V Ananth, Jason D Wright, Zainab Siddiq, Mary E DʼAlton, Alexander M Friedman
OBJECTIVE: To characterize probabilities of vaginal delivery based on second-stage duration along with maternal and neonatal risks for women undergoing labor after cesarean delivery. METHODS: This unplanned secondary analysis of the Maternal-Fetal Medicine Units Cesarean Registry, a prospective observational cohort, assessed outcomes in women with a prior uterine scar and included women with a previous cesarean delivery without prior vaginal delivery who reached the second stage of labor...
February 5, 2018: Obstetrics and Gynecology
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