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https://www.readbyqxmd.com/read/27908844/quittr-the-design-of-a-video-game-to-support-smoking-cessation
#1
Ivan Bindoff, Kristy de Salas, Gregory Peterson, Tristan Ling, Ian Lewis, Lindsay Wells, Peter Gee, Stuart G Ferguson
BACKGROUND: Smoking is recognized as the largest, single, preventable cause of death and disease in the developed world. While the majority of smokers report wanting to quit, and many try each year, smokers find it difficult to maintain long-term abstinence. Behavioral support, such as education, advice, goal-setting, and encouragement, is known to be beneficial in improving the likelihood of succeeding in a quit attempt, but it remains difficult to effectively deliver this behavioral support and keep the patient engaged with the process for a sufficient duration...
December 1, 2016: JMIR Serious Games
https://www.readbyqxmd.com/read/27908605/direct-health-care-costs-associated-with-obesity-in-chinese-population-in-2011
#2
Jingcheng Shi, Yao Wang, Wenwei Cheng, Hui Shao, Lizheng Shi
AIMS: Overweight and obesity are established major risk factors for type 2 diabetes, and major public health concerns in China. This study aims to assess the economic burden associated with overweight and obesity in the Chinese population ages 45 and older. METHODS: The Chinese Health and Retirement Longitudinal Study (CHARLS) in 2011 included 13,323 respondents of ages 45 and older living in 450 rural and urban communities across China. Demographic information, height, weight, direct health care costs for outpatient visits, hospitalization, and medications for self-care were extracted from the CHARLS database...
November 12, 2016: Journal of Diabetes and its Complications
https://www.readbyqxmd.com/read/27895218/a-new-approach-to-identify-high-burnout-medical-staffs-by-kernel-k-means-cluster-analysis-in-a-regional-teaching-hospital-in-taiwan
#3
Yii-Ching Lee, Shian-Chang Huang, Chih-Hsuan Huang, Hsin-Hung Wu
This study uses kernel k-means cluster analysis to identify medical staffs with high burnout. The data collected in October to November 2014 are from the emotional exhaustion dimension of the Chinese version of Safety Attitudes Questionnaire in a regional teaching hospital in Taiwan. The number of effective questionnaires including the entire staffs such as physicians, nurses, technicians, pharmacists, medical administrators, and respiratory therapists is 680. The results show that 8 clusters are generated by kernel k-means method...
2016: Inquiry: a Journal of Medical Care Organization, Provision and Financing
https://www.readbyqxmd.com/read/27886085/dirty-money-a-matter-of-bacterial-survival-adherence-and-toxicity
#4
Frank Vriesekoop, Jing Chen, Jenna Oldaker, Flavien Besnard, Reece Smith, William Leversha, Cheralee Smith-Arnold, Julie Worrall, Emily Rufray, Qipeng Yuan, Hao Liang, Amalia Scannell, Cryn Russell
In this study we report the underlying reasons to why bacteria are present on banknotes and coins. Despite the use of credit cards, mobile phone apps, near-field-communication systems, and cryptocurrencies such as bitcoins which are replacing the use of hard currencies, cash exchanges still make up a significant means of exchange for a wide range of purchases. The literature is awash with data that highlights that both coins and banknotes are frequently identified as fomites for a wide range of microorganisms...
November 23, 2016: Microorganisms
https://www.readbyqxmd.com/read/27876550/eukaryotic-phosphate-homeostasis-the-inositol-pyrophosphate-perspective
#5
REVIEW
Cristina Azevedo, Adolfo Saiardi
Phosphate, as a cellular energy currency, essentially drives most biochemical reactions defining living organisms, and thus its homeostasis must be tightly regulated. Investigation into the role of inositol pyrophosphates (PP-IPs) has provided a novel perspective on the regulation of phosphate homeostasis. Recent data suggest that metabolic and signaling interplay between PP-IPs, ATP, and inorganic polyphosphate (polyP) influences and is influenced by cellular phosphate homeostasis. Different studies have demonstrated that the SPX protein domain is a key component of proteins involved in phosphate metabolism...
November 19, 2016: Trends in Biochemical Sciences
https://www.readbyqxmd.com/read/27833835/comparison-of-pharmaceutical-pricing-and-reimbursement-systems-in-turkey-and-certain-eu-countries
#6
Enver Kagan Atikeler, Gulbin Özçelikay
Recently, the need for health care services has increased gradually and the limitations in sources allocated for this area have been recognized. Moving from this fact, it has gained a supreme importance to determine what health programs or technologies will be given priority. According to Danzon (Reference pricing: theory and evidence, reference pricing and pharmaceutical policy: perspectives on economics and innovation, springer, New York, pp 86-126, 2001), arrangements towards controlling the expenses through price and profit controls, reimbursement methods and incentives have recently gained wide currency...
2016: SpringerPlus
https://www.readbyqxmd.com/read/27827919/taming-prebiotic-chemistry-the-role-of-heterogeneous-and-interfacial-catalysis-in-the-emergence-of-a-prebiotic-catalytic-information-polymer-system
#7
REVIEW
Pierre-Alain Monnard
Cellular life is based on interacting polymer networks that serve as catalysts, genetic information and structural molecules. The complexity of the DNA, RNA and protein biochemistry suggests that it must have been preceded by simpler systems. The RNA world hypothesis proposes RNA as the prime candidate for such a primal system. Even though this proposition has gained currency, its investigations have highlighted several challenges with respect to bulk aqueous media: (1) the synthesis of RNA monomers is difficult; (2) efficient pathways for monomer polymerization into functional RNAs and their subsequent, sequence-specific replication remain elusive; and (3) the evolution of the RNA function towards cellular metabolism in isolation is questionable in view of the chemical mixtures expected on the early Earth...
November 4, 2016: Life
https://www.readbyqxmd.com/read/27822154/supplementary-searches-of-pubmed-to-improve-currency-of-medline-and-medline-in-process-searches-via-ovid
#8
Steven Duffy, Shelley de Kock, Kate Misso, Caro Noake, Janine Ross, Lisa Stirk
OBJECTIVE: The research investigated whether conducting a supplementary search of PubMed in addition to the main MEDLINE (Ovid) search for a systematic review is worthwhile and to ascertain whether this PubMed search can be conducted quickly and if it retrieves unique, recently published, and ahead-of-print studies that are subsequently considered for inclusion in the final systematic review. METHODS: Searches of PubMed were conducted after MEDLINE (Ovid) and MEDLINE In-Process (Ovid) searches had been completed for seven recent reviews...
October 2016: Journal of the Medical Library Association: JMLA
https://www.readbyqxmd.com/read/27822052/costs-of-inguinal-hernia-repair-associated-with-using-different-medical-devices-in-the-czech-republic
#9
Petra Marešová, Matus Peteja, Milan Lerch, Pavel Zonca, Kamil Kuca
OBJECTIVE: Inguinal hernia repair is one of the most frequently carried out operations worldwide. The purpose of this article is to analyze the costs of hernia repair and to specify the loss or profit made under the conditions in the Czech Republic with respect to the currently used medical devices and approaches. METHODS: This article is based on the Drummond and O'Brien methodology, which specifically determines the content of direct and indirect costs in health services...
2016: Therapeutics and Clinical Risk Management
https://www.readbyqxmd.com/read/27819748/topical-antibiotics-for-preventing-surgical-site-infection-in-wounds-healing-by-primary-intention
#10
REVIEW
Clare F Heal, Jennifer L Banks, Phoebe D Lepper, Evangelos Kontopantelis, Mieke L van Driel
BACKGROUND: Surgical site infections (SSI) can delay wound healing, impair cosmetic outcome and increase healthcare costs. Topical antibiotics are sometimes used to reduce microbial contaminant exposure following surgical procedures, with the aim of reducing SSIs. OBJECTIVES: The primary objective of this review was to determine whether the application of topical antibiotics to surgical wounds that are healing by primary intention reduces the incidence of SSI and whether it increases the incidence of adverse outcomes (allergic contact dermatitis, infections with patterns of antibiotic resistance and anaphylaxis)...
November 7, 2016: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/27808039/neurodegeneration-in-accelerated-aging
#11
Moren Scheibye-Knudsen
The growing proportion of elderly people represents an increasing economic burden, not least because of age-associated diseases that pose a significant cost to the health service. Finding possible interventions to age-associated disorders therefore have wide ranging implications. A number of genetically defined accelerated aging diseases have been characterized that can aid in our understanding of aging. Interestingly, all these diseases are associated with defects in the maintenance of our genome. A subset of these disorders, Cockayne syndrome, Xeroderma pigmentosum group A and ataxia-telangiectasia, show neurological involvement reminiscent of what is seen in primary human mitochondrial diseases...
November 2016: Danish Medical Journal
https://www.readbyqxmd.com/read/27787610/polymorphism-of-the-brain-derived-neurotrophic-factor-and-dynamics-of-the-seizure-threshold-of-electroconvulsive-therapy
#12
C Stephani, M Shoukier, R Ahmed, C Wolff-Menzler
During a course of electroconvulsive therapy (ECT), the level of currency necessary to induce an epileptic seizure in a patient may either remain relatively stable or-more often-may require repeated upward adjustment over time due to a constantly increasing seizure threshold. We aimed to determine whether a common polymorphism of the brain-derived neurotrophic factor (BDNF), which constitutes an important and ubiquitously expressed neurotrophine in the brain, affects the stimulation threshold of ECTs required to induce an epileptic seizure over time...
October 27, 2016: European Archives of Psychiatry and Clinical Neuroscience
https://www.readbyqxmd.com/read/27766615/continuous-improvement-in-national-art-standards-by-the-rtac-accreditation-system-in-australia-and-new-zealand
#13
Keith Harrison, John Peek, Michael Chapman, Mark Bowman
BACKGROUND: Assisted reproductive technology (ART) clinics in Australia and New Zealand are accredited and licensed against a Code of Practice audited by certifying bodies accredited by the Joint Accreditation System for Australia and New Zealand (JAS-ANZ). The system is administered by the Reproductive Technology Accreditation Committee (RTAC) of the Fertility Society of Australia. AIMS: To review the incidence of variances and findings identified by certifying bodies in Australian and New Zealand ART clinics within the currency of a single version of the Code of Practice...
October 21, 2016: Australian & New Zealand Journal of Obstetrics & Gynaecology
https://www.readbyqxmd.com/read/27764655/the-quality-and-outcomes-framework-body-commodification-in-uk-general-practice
#14
Armando H Norman, Andrew J Russell, Claudia Merli
The UK's Quality and Outcomes Framework (QOF) is the largest pay-for-performance scheme in the world. This ethnographic study explored how QOF's monetary logic influences the approach to healthcare in UK general practice. From August 2013 to April 2014, we researched two UK general practice surgeries and one general practice training programme. These environments provided the opportunity for studying various spaces such as QOF meetings, consultation rooms, QOF recoding sessions, and the collection of computer-screen images depicting how patients' biomarkers are evaluated and costed through software systems...
October 11, 2016: Social Science & Medicine
https://www.readbyqxmd.com/read/27760002/midbrain-dopamine-neurons-signal-aversion-in-a-reward-context-dependent-manner
#15
Hideyuki Matsumoto, Ju Tian, Naoshige Uchida, Mitsuko Watabe-Uchida
Dopamine is thought to regulate learning from appetitive and aversive events. Here we examined how optogenetically-identified dopamine neurons in the lateral ventral tegmental area of mice respond to aversive events in different conditions. In low reward contexts, most dopamine neurons were exclusively inhibited by aversive events, and expectation reduced dopamine neurons' responses to reward and punishment. When a single odor predicted both reward and punishment, dopamine neurons' responses to that odor reflected the integrated value of both outcomes...
October 19, 2016: ELife
https://www.readbyqxmd.com/read/27738861/spatio-temporal-genotypic-and-environmental-effects-on-plant-soluble-protein-and-digestible-carbohydrate-content-implications-for-insect-herbivores-with-cotton-as-an-exemplar
#16
Carrie A Deans, Spencer T Behmer, Justin Fiene, Gregory A Sword
Plant soluble protein and digestible carbohydrate content significantly affect insect herbivore fitness, but studies reporting plant protein and carbohydrate content are rare. Instead, the elements nitrogen and carbon often are used as surrogates for plant protein and digestible carbohydrate content, respectively. However, this is problematic for two reasons. First, carbon is found in all organic molecules, which precludes strong correlations with ecologically important dietary macronutrients (e.g., digestible carbohydrates, the primary energy source for most insect herbivores)...
November 2016: Journal of Chemical Ecology
https://www.readbyqxmd.com/read/27738240/youtube-as-a-potential-source-of-information-on-deep-venous-thrombosis
#17
Mehmet Ş Bademci, Serkan Yazman, Tevfik Güneş, Gokhan Ocakoglu, Kaptanderya Tayfur, Orhan Gokalp
BACKGROUND: No work has been reported on the use of video websites to learn about deep vein thrombosis and the value of education using them. We examined the characteristics and scientific accuracy of videos related to deep vein thrombosis on YouTube. METHODS: YouTube was surveyed using no filter and the key words 'deep vein thrombosis' and 'leg vein clot' in June 2016. The videos evaluated were divided into three groups in terms of their scientific content, accuracy, and currency: useful, partly useful, and useless...
October 12, 2016: Phlebology
https://www.readbyqxmd.com/read/27729101/auditing-emergency-management-programmes-measuring-leading-indicators-of-programme-performance
#18
Heather Tomsic
Emergency Management Programmes benefit from review and measurement against established criteria. By measuring current vs required programme elements for their actual currency, completeness and effectiveness, the resulting timely reports of achievements and documentation of identified gaps can effectively be used to rationally support prioritised improvement. Audits, with their detailed, triangulated and objectively weighted processes, are the ultimate approach in terms of programme content measurement. Although Emergency Management is often presented as a wholly separate operational mechanism, distinct and functionally different from the organisation's usual management structure, this characterisation is only completely accurate while managing an emergency itself...
2016: Journal of Business Continuity & Emergency Planning
https://www.readbyqxmd.com/read/27712715/financing-a-cure-for-diabetes-in-a-multipayer-environment
#19
Anirban Basu, Prasun Subedi, Sachin Kamal-Bahl
BACKGROUND: Financing medical breakthroughs or cures is becoming increasingly challenging in the current fiscal environment. OBJECTIVES: In this paper, we develop the precise conditions needed for a financing mechanism, HealthCoin, to work between a private payer and Medicare, to incentivize the former to invest in breakthrough therapies or cures in the US. METHODS: We illustrate the valuation of such a currency for a cure of Type 2 diabetes...
September 2016: Value in Health: the Journal of the International Society for Pharmacoeconomics and Outcomes Research
https://www.readbyqxmd.com/read/27708738/are-we-economically-efficient-enough-to-increase-the-potential-of-in-vitro-proliferation-of-osteoblasts-by-means-of-pharmacochemical-agents
#20
Mehmet Isyar, Seyit Ali Gumustas, Ibrahim Yilmaz, Duygu Yasar Sirin, Hacı Bayram Tosun, Mahir Mahirogullari
BACKGROUND: The aim of this study was to test the necessity of using expensive and unaccesible pharmacological-chemical agents in the proliferation of bone tissue cultures and in the induction of mineralized matrix formation to increase the osteogenic effect. METHODS: For this purpose, human primary cell cultures were prepared and then divided into two groups. Whereas the cells in group I were fed with an osteoblast stimulator medium containing Dulbecco's Modified Eagle Medium (DMEM) and β-glycerophosphate, the cells in group II were fed with DMEM containing dexamethasone and 2-phospho-L-ascorbic acid trisodium salt...
2016: Open Orthopaedics Journal
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