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https://www.readbyqxmd.com/read/29773451/total-hip-arthroplasty-for-posttraumatic-osteoarthritis-following-acetabular-fracture-a-systematic-review-of-characteristics-outcomes-and-complications
#1
Robert D Stibolt, Harshadkumar A Patel, Samuel R Huntley, Eva J Lehtonen, Ashish B Shah, Sameer M Naranje
PURPOSE: Posttraumatic arthritis (PTA) may develop years after acetabular fracture, hindering joint function and causing significant chronic musculoskeletal pain. Given the delayed onset of PTA, few studies have assessed outcomes of delayed total hip arthroplasty (THA) in acetabular fracture patients. This study systematically reviewed the literature for outcomes of THA in patients with PTA and prior acetabular fracture. METHODS: Pubmed, EMBASE, SCOPUS, and Cochrane library were searched for articles containing the keywords "acetabular", "fracture", "arthroplasty", and "post traumatic arthritis" published between 1995 and August 2017...
April 26, 2018: Chinese Journal of Traumatology, Zhonghua Chuang Shang za Zhi
https://www.readbyqxmd.com/read/29772343/brain-stimulation-differentially-modulates-nociception-and-inflammation-in-aversive-and-non-aversive-behavioural-conditions
#2
G S Bassi, A Kanashiro, G J Rodrigues, F Q Cunha, N C Coimbra, L Ulloa
Inflammation and pain are major clinical burdens contributing to multiple disorders and limiting the quality of life of patients. We previously reported that brain electrical stimulation can attenuate joint inflammation in experimental arthritis. Here, we report that non-aversive electrical stimulation of the locus coeruleus (LC), the paraventricular hypothalamic nucleus (PVN) or the ventrolateral column of the periaqueductal grey matter (vlPAG) decreases thermal pain sensitivity, knee inflammation and synovial neutrophilic infiltration in ratswith intra-articular zymosan...
May 14, 2018: Neuroscience
https://www.readbyqxmd.com/read/29771395/glucosamine-and-chondroitin-sulfate-what-has-been-learned-since-the-glucosamine-chondroitin-arthritis-intervention-trial
#3
Nicholas DiNubile
Glucosamine and chondroitin sulfate, alone or in combination, are used worldwide by individuals suffering from osteoarthritis pain. They are by prescription in some countries but are available as over-the-counter dietary supplements in other countries, such as the United States. The inconclusive results of the National Institutes of Health-sponsored Glucosamine/chondroitin Arthritis Intervention Trial (GAIT) did little to clarify the efficacy of these agents. However, some newer studies have provided a better perspective on the potential benefits that they can offer...
May 16, 2018: Orthopedics
https://www.readbyqxmd.com/read/29765185/the-immediate-effects-of-taping-therapy-on-knee-pain-and-depression-in-patients-with-degenerative-arthritis
#4
Ji-Won Han, Dong-Kyu Lee, Chi-Bok Park
[Purpose] This study aims to identify the immediate effects of taping therapy on knee pain and depression among patients with degenerative arthritis. [Subjects and Methods] In total, 32 patients with degenerative arthritis were randomly assigned to one of two groups: the experimental group that underwent taping therapy and the control group that underwent regular treatment (16 patients per group). In the experimental group, therapeutic tape was wrapped all around the knee joint. Pain and depression were measured using the visual analogue scale (VAS) and the Beck Depression Inventory (BDI), respectively...
May 2018: Journal of Physical Therapy Science
https://www.readbyqxmd.com/read/29753098/anti-arthritic-activities-of-ethanol-extracts-of-circaea-mollis-siebold-zucc-whole-plant-in-rodents
#5
Yanhong Yu, Qing Zhang, Jiajia Li, Yeli Guan, Jiangeng Huang, Zhiping Wang, Zhen Zhang, Wenrui Zhang, Jing Guo, Jinghua Li, Jiachun Chen, Qun Zhou
ETHNOPHARMACOLOGICAL RELEVANCE: Circaea mollis Siebold & Zucc., a genus of Circaea that follows Onagraceae, has been used for centuries as a folk herb in traditional Chinese medicine (TCM) and Hani Ethnopharmacy for the treatment of joint swelling and pain in rheumatoid arthritis. AIM OF THE STUDY: This study was designed to confirm anti-arthritic effects and its underlying mechanism of ethanol extracts of Circaea mollis Siebold & Zucc. (EEC), which may contribute to provide the pharmacological basis in the treatment of rheumatoid disease...
May 9, 2018: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/29752508/comparison-of-shoulder-replacement-to-treat-osteoarthritis-secondary-to-instability-surgery-and-primary-osteoarthritis-a-retrospective-controlled-study-of-patient-outcomes
#6
Giovanni Merolla, Simone Cerciello, Stefano Marenco, Elisabetta Fabbri, Paolo Paladini, Giuseppe Porcellini
PURPOSE: We hypothesized that osteoarthritis developing after instability surgery is radiographically similar to primary arthritis and that arthroplasty provides comparable outcomes in patients with these two types of osteoarthritis. METHODS: Patients with osteoarthritis due to instability surgery (group I) and with primary osteoarthritis (group II) were included. Mean follow-up was 52.6 and 41.6 months, respectively. Hemiarthroplasties (HA) were 32% in group I and 27% in group II; total shoulder arthroplasties (TSA) were 68 and 73% respectively...
May 12, 2018: International Orthopaedics
https://www.readbyqxmd.com/read/29752179/the-effect-of-eicosapentaenoic-and-docosahexaenoic-acids-on-physical-function-exercise-and-joint-replacement-in-patients-with-coronary-artery-disease-a-secondary-analysis-of-a-randomized-clinical-trial
#7
Abdulhamied Alfaddagh, Tarec K Elajami, Mohamad Saleh, Mohamad Elajami, Bruce R Bistrian, Francine K Welty
BACKGROUND: Poor physical function impairs fitness and exercise and is associated with worse cardiovascular outcomes and all-cause mortality. Joint pain and stiffness limit physical function. OBJECTIVE: To determine if eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) supplementation improves physical function and exercise in coronary artery disease (CAD) patients. METHODS: A total of 291 subjects with stable CAD were randomized to either Lovaza (1...
March 14, 2018: Journal of Clinical Lipidology
https://www.readbyqxmd.com/read/29749723/high-controlled-diffusion-drug-release-from-ureasil-poly-ethylene-oxide-na-montmorillonite-hybrid-hydrogel-nanocomposites
#8
Celso Ricardo Jesus, Eduardo Ferreira Molina, Sandra Helena Pulcinelli, Celso V Santilli
In this work, we report the effects of incorporation of variable amounts (1-20 wt%) of sodium montmorillonite (MMT) into a siloxane-poly(ethylene oxide) hybrid hydrogel prepared by the sol-gel route. The aim was to control the nanostructural features of the nanocomposite, improve the release profile of the drug sodium diclofenac (SDCF), and optimize the swelling behavior of the hydrophilic matrix. The nanoscopic characteristics of the siloxane-crosslinked poly(ethylene oxide) network, the semi-crystallinity of the hybrid, and the intercalated or exfoliated structure of the clay were investigated by X-ray diffraction (XRD), small-angle X-ray scattering (SAXS), and differential scattering calorimetry (DSC)...
May 11, 2018: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/29748070/morphometric-tibial-implant-decreases-posterior-overhang-rate-and-improves-clinical-outcomes-results-of-a-prospective-matched-controlled-study
#9
Paul Bizzozero, Yassine Bulaid, Xavier Flecher, Matthieu Ollivier, Sébastien Parratte, Jean-Noel Argenson
BACKGROUND: Tibial implant's positioning in total knee arthroplasty (TKA) requires a compromise between implant's rotation and bone coverage. We hypothesized that morphometric tibial trays (MTTs) would improve implant positioning and clinical outcomes as compared with symmetrical tibial trays. METHODS: Thirty-three patients were included prospectively according to the following criteria: age from 18 to 85 years, body mass index <35 kg/m2 , and posterostabilized cemented TKA performed for primary arthritis...
April 19, 2018: Journal of Arthroplasty
https://www.readbyqxmd.com/read/29739493/the-treatment-of-primary-arthritis-of-the-finger-and-thumb-joint
#10
Christian Karl Spies, Martin Langer, Peter Hahn, Lars Peter Müller, Frank Unglaub
BACKGROUND: Primary finger and thumb joint arthritis is common, with a markedly rising prevalence from age 50 onward. As the population as a whole ages, the need for effective, stage-appropriate treatment of this condition is increasing. METHODS: This review is based on pertinent publications retrieved by a selective search in the PubMed and Cochrane Library databases. RESULTS: Pain on movement and morning stiffness are commonly reported symptoms...
April 20, 2018: Deutsches Ärzteblatt International
https://www.readbyqxmd.com/read/29729412/sustained-intra-articular-release-of-celecoxib-in-an-equine-repeated-lps-synovitis-model
#11
Stefan M Cokelaere, Saskia G M Plomp, Esther de Boef, Mike de Leeuw, Sophie Bool, Chris H A van de Lest, P René van Weeren, Nicoline M Korthagen
Synovial inflammation is an important characteristic of arthritic disorders like osteoarthritis and rheumatoid arthritis. Orally administered non-steroidal anti-inflammatory drugs (NSAIDs) such as celecoxib are among the most widely prescribed drugs to manage these debilitating diseases. Intra-articular delivery in biodegradable in situ forming hydrogels overcomes adverse systemic effects and prolongs drug retention in the joint. In this study two formulations of celecoxib (40 mg/g and 120 mg/g) in a propyl-capped PCLA-PEG-PCLA triblock copolymer were sequentially evaluated in a multiple LPS challenge equine synovitis model...
May 2, 2018: European Journal of Pharmaceutics and Biopharmaceutics
https://www.readbyqxmd.com/read/29717032/responsiveness-of-single-versus-composite-measures-of-pain-in-knee-osteoarthritis
#12
Matthew J Parkes, Michael J Callaghan, Leslie Tive, Mark Lunt, David T Felson
OBJECTIVE: In rheumatoid arthritis, composite outcomes constructed from a combination of outcome measures are widely used to enhance responsiveness (sensitivity to change) and comprehensively summarize response. Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) pain is the primary outcome measure in many osteoarthritis (OA) trials. Information from other outcomes, such as rescue medication use and other WOMAC subscales, could be added to create composite outcomes, but the sensitivity of such a composite has not been tested...
May 1, 2018: Journal of Rheumatology
https://www.readbyqxmd.com/read/29705475/the-effects-of-reflexology-on-pain-and-sleep-deprivation-in-patients-with-rheumatoid-arthritis-a-randomized-controlled-trial
#13
Ercan Bakir, Sevgin Samancioglu Baglama, Savas Gursoy
OBJECTIVE: This study was intended to examine the effect of foot reflexology on RA patients' pain and sleep quality. METHODS: This is a randomized controlled trial and was held at the "Rheumatology Follow-up Polyclinic" in Turkey between January-July 2015. A total of 60 patients were included in the research. A sociodemographic data form, the Pittsburgh Sleep Quality Index (PSQI) and the Visual Analogue Scale (VAS) were used. Foot Reflexology was administered to the experimental group...
May 2018: Complementary Therapies in Clinical Practice
https://www.readbyqxmd.com/read/29703851/efficacy-and-safety-of-faecal-microbiota-transplantation-in-patients-with-psoriatic-arthritis-protocol-for-a-6-month-double-blind-randomised-placebo-controlled-trial
#14
Maja Skov Kragsnaes, Jens Kjeldsen, Hans Christian Horn, Heidi Lausten Munk, Finn Moeller Pedersen, Hanne Marie Holt, Jens Kristian Pedersen, Dorte Kinggaard Holm, Henning Glerup, Vibeke Andersen, Ulrich Fredberg, Karsten Kristiansen, Robin Christensen, Torkell Ellingsen
INTRODUCTION: An unbalanced intestinal microbiota may mediate activation of the inflammatory pathways seen in psoriatic arthritis (PsA). A randomised, placebo-controlled trial of faecal microbiota transplantation (FMT) infused into the small intestine of patients with PsA with active peripheral disease who are non-responsive to methotrexate (MTX) treatment will be conducted. The objective is to explore clinical aspects associated with FMT performed in patients with PsA. METHODS AND ANALYSIS: This trial is a randomised, two-centre stratified, double-blind (patient, care provider and outcome assessor), placebo-controlled, parallel-group study...
April 27, 2018: BMJ Open
https://www.readbyqxmd.com/read/29703452/a-population-based-examination-of-the-co-occurrence-and-functional-correlates-of-chronic-pain-and-generalized-anxiety-disorder
#15
Brian Csupak, Jordana L Sommer, Eric Jacobsohn, Renée El-Gabalawy
OBJECTIVES: This study aimed to: 1) Establish the prevalence of co-occurring chronic pain conditions (i.e., arthritis, back pain, and migraines) and generalized anxiety disorder (GAD), and 2) Examine levels of pain severity, disability, and work absenteeism among comorbid chronic pain conditions and GAD. METHODS: Data were analyzed from the 2012 Canadian Community Health Survey-Mental Health (CCHS-MH; N = 25,113). Chi-square analyses assessed whether significant differences existed in pain severity in those with comorbid chronic pain and GAD versus pain conditions alone...
April 17, 2018: Journal of Anxiety Disorders
https://www.readbyqxmd.com/read/29691361/salvianolic-acid-b-suppresses-inflammatory-mediator-levels-by-downregulating-nf-%C3%AE%C2%BAb-in-a-rat-model-of-rheumatoid-arthritis
#16
Zeng-Bing Xia, Yong-Jian Yuan, Qiang-Hua Zhang, Heng Li, Ji-Lin Dai, Ji-Kang Min
BACKGROUND Salvianolic acid B (SB) is a major active phyto-component of the plant Radix Salvia miltiorrhiza, which is traditionally used to treat joint pain and arthritis. The present study examined the anti-rheumatoid arthritis efficacy of SB on collagen-induced rheumatoid arthritis (CIA) in a rat model. MATERIAL AND METHODS Forty-eight rats were divided into 4 groups: Control rats treated with saline (Group I), rats subjected to CIA induction by intradermal injection of bovine collagen II type at the tail (Group II), and rats subjected to CIA and supplemented with either 20 or 40 mg/kg of SB for 28 days (group III or IV)...
April 25, 2018: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://www.readbyqxmd.com/read/29685482/patient-acceptable-symptom-state-and-minimal-clinically-important-difference-for-patient-reported-outcomes-in-systemic-sclerosis-a-secondary-analysis-of-a-randomized-controlled-trial-comparing-personalized-physical-therapy-to-usual-care
#17
Camille Daste, François Rannou, Luc Mouthon, Katherine Sanchez, Alexandra Roren, Vincent Tiffreau, Éric Hachulla, Philippe Thoumie, Jean Cabane, Emmanuel Chatelus, Jean Sibilia, Serge Poiraudeau, Christelle Nguyen
BACKGROUND: To estimate patient acceptable symptom state (PASS) and minimal clinically important difference (MCID) for patient-reported outcomes in systemic sclerosis (SSc). METHODS: We conducted a secondary analysis of the SCLEREDUC trial, a 12-month randomized controlled trial comparing the efficacy of physical therapy to usual care in 220 SSc patients followed-up from September 2005 to October 2010. Self-rated state and change in patient health at 12 months were assessed by using 2 external anchors extracted from the Medical Outcomes Study 36-Item Short-Form...
March 27, 2018: Seminars in Arthritis and Rheumatism
https://www.readbyqxmd.com/read/29670337/uk-south-asian-patients-experiences-of-and-satisfaction-toward-receiving-information-about-biologics-in-rheumatoid-arthritis
#18
Kanta Kumar, Sabrina R Raizada, Christian D Mallen, Rebecca J Stack
Background: Rheumatoid arthritis (RA) causes painful joint inflammation and is incurable, but treatments control RA. Drug regimens are complex, and patients often do not take their medication as expected. Poor medication adherence can lead to poorly controlled disease and worse patient outcomes. Biologics treatments are expensive and require full engagement from patients. We have previously shown that patients from Black ethnic minority backgrounds do not fully engage into treatment plan...
2018: Patient Preference and Adherence
https://www.readbyqxmd.com/read/29669470/web-based-rehabilitation-interventions-for-people-with-rheumatoid-arthritis-a-systematic-review
#19
Cynthia Srikesavan, Catherine Bryer, Usama Ali, Esther Williamson
Background Rehabilitation approaches for people with rheumatoid arthritis include joint protection, exercises and self-management strategies. Health interventions delivered via the web have the potential to improve access to health services overcoming time constraints, physical limitations, and socioeconomic and geographic barriers. The objective of this review is to determine the effects of web-based rehabilitation interventions in adults with rheumatoid arthritis. Methods Randomised controlled trials that compared web-based rehabilitation interventions with usual care, waiting list, no treatment or another web-based intervention in adults with rheumatoid arthritis were included...
January 1, 2018: Journal of Telemedicine and Telecare
https://www.readbyqxmd.com/read/29666030/resection-arthroplasty-compared-with-total-hip-arthroplasty-in-treating-chronic-hip-pain-of-patients-with-a-history-of-substance-abuse
#20
William Curtis, Meir Marmor
BACKGROUND: Retrospective comparison of surgical management of severe hip pain in patients with a history of substance abuse treated by modified Girdlestone resection arthroplasty (RA) vs delayed total hip arthroplasty (THA) following yearlong sobriety pathway. METHODS: Patients were identified using charts, current procedural terminology (CPT) code query, and THA sobriety pathway registry. The primary outcome was adequate pain control following surgery, defined as visual analog scale ≤ 5 or verbal description of "moderate" or lower pain...
March 16, 2018: Journal of Arthroplasty
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