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https://www.readbyqxmd.com/read/29896560/single-dose-lidocaine-spinal-anesthesia-in-hip-and-knee-arthroplasty
#1
Nicholas B Frisch, Brian Darrith, Dane C Hansen, Adrienne Wells, Sheila Sanders, Richard A Berger
Background: With the increasing interest in fast recovery and outpatient joint arthroplasty, short-acting local anesthetic agents and minimal narcotic use are preferred. Lidocaine is a fast-onset, short-duration local anesthetic that has been used for many years in spinal anesthesia. However, lidocaine spinal anesthesia has been reported to have a risk of transient neurologic symptoms (TNSs). The purpose of this study is to determine the safety and efficacy of single-dose lidocaine spinal anesthesia in the setting of outpatient joint arthroplasty...
June 2018: Arthroplasty Today
https://www.readbyqxmd.com/read/29896558/are-reinfusion-drains-safe-to-use-with-periarticular-liposomal-bupivacaine-an-analysis-of-systemic-bupivacaine-toxicity
#2
Marc R Angerame, Gavin P Hart, Susan M Odum, Bryan D Springer
Background: Intraoperative periarticular injection (PAI) with local anesthetic is an important component of multimodal pain control in total joint arthroplasty (TJA). A potential risk of this practice is serum anesthetic toxicity resulting from the autotransfusion of blood collected from a reinfusion drain. The purpose of this study is to evaluate the levels of bupivacaine in blood collected in an autotransfusion system after use of a PAI in TJA. Methods: In this prospective study, each TJA patient had an identical PAI consisting of 20 cc of liposomal bupivacaine, 30 cc of 0...
June 2018: Arthroplasty Today
https://www.readbyqxmd.com/read/29896554/association-of-rapidly-destructive-osteoarthritis-of-the-hip-with-intra-articular-steroid-injections
#3
Shane R Hess, Robert S O'Connell, Christopher P Bednarz, Andrew C Waligora, Gregory J Golladay, William A Jiranek
Background: To assess the relationship between rapidly destructive osteoarthritis (RDOA) of the hip and intra-articular steroid injections. Methods: Coding records from 2000 to 2013 were used to identify all subjects who had a fluoroscopy-guided intra-articular hip injection to treat pain associated with primary osteoarthritis. Radiographic measurements from preinjection and postinjection imaging were evaluated with Luquesne's classification of RDOA to determine diagnosis (greater than 50% joint space narrowing or greater than 2 mm of cartilage loss in 1 year with no other forms of destructive arthropathy)...
June 2018: Arthroplasty Today
https://www.readbyqxmd.com/read/29896550/rapid-destructive-osteoarthritis-of-the-hip-after-intra-articular-steroid-injection
#4
Anurag Tiwari, Yugal Karkhur, James A Keeney, Ajay Aggarwal
Rapid destructive osteoarthritis of the hip is a separate entity different from the usual osteoarthritis. It is usually seen in elderly women, and the characteristic feature is the rapid progression within 6 to 12 months to complete destruction of the joint. The exact etiology is not known. We present a rare case of rapid destructive osteoarthritis of the hip in a 62-year-old woman who developed it within 2 months of intra-articular steroid injection, which was managed well with uncemented total hip arthroplasty...
June 2018: Arthroplasty Today
https://www.readbyqxmd.com/read/29890864/effect-of-periarticular-morphine-injection-for-total-hip-arthroplasty-a-randomised-double-blind-trial
#5
Kentaro Iwakiri, Yoichi Ohta, Yukihide Minoda, Akio Kobayashi, Hiroaki Nakamura
BACKGROUND: The periarticular multimodal cocktail injection is currently commonly used to treat postoperative pain after total hip arthroplasty (THA). Despite its analgesic effect, it is frequently reported to cause nausea and vomiting, which are adverse effects of opioids. This study aimed to assess the efficacy of morphine as a component of a multimodal cocktail injection for providing postoperative analgesia and alleviating swelling in patients who underwent THA. MATERIALS AND METHODS: This was a prospective, single-centre, randomised controlled trial involving 100 patients scheduled for unilateral THA...
June 1, 2018: Hip International: the Journal of Clinical and Experimental Research on Hip Pathology and Therapy
https://www.readbyqxmd.com/read/29888808/changes-in-proinflammatory-cytokines-neuropeptides-and-microglia-in-an-animal-model-of-monosodium-iodoacetate-induced-hip-osteoarthritis
#6
Yuya Kawarai, Sumihisa Orita, Junichi Nakamura, Shuichi Miyamoto, Miyako Suzuki, Kazuhide Inage, Shigeo Hagiwara, Takane Suzuki, Takayuki Nakajima, Tsutomu Akazawa, Seiji Ohtori
The aim of this study was to investigate the local production of proinflammatory cytokines, pain- related sensory innervation of dorsal-root ganglia (DRG), and spinal changes in a rat model of induced hip osteoarthritis (OA). Seventy-five Sprague Dawley rats were used, including 25 controls and 50 injected into the right hip joints (sham group, injected with 25 µl of sterile saline: N =25; and monosodium iodoacetate (MIA) group, injected with 25 µl of sterile saline with 2 mg of MIA: N = 25). We measured the local production of TNF-α, immunoreactive (-ir) neurons for calcitonin gene-related peptide (CGRP) and growth associated protein-43 (GAP-43) in DRG, and immunoreactive neurons for ionized-calcium-binding adaptor molecule-1 (Iba-1) in the dorsal horn of spinal cord, on post-induction days 7, 14, 28, 42, and 56 (N = 5 rats/group/time point)...
June 11, 2018: Journal of Orthopaedic Research: Official Publication of the Orthopaedic Research Society
https://www.readbyqxmd.com/read/29873812/alcohol-consumption-and-bone-mineral-density-in-people-with-hiv-and-substance-use-disorder-a-prospective-cohort-study
#7
Richard Saitz, Aldina Mesic, Alicia S Ventura, Michael R Winter, Timothy C Heeren, Meg M Sullivan, Alexander Y Walley, Gregory J Patts, Seville M Meli, Michael F Holick, Theresa W Kim, Kendall J Bryant, Jeffrey H Samet
BACKGROUND: People living with HIV (PLWH) commonly have low bone mineral density (BMD) (low bone mass and osteoporosis) and are at high risk for fractures. Fractures and low BMD are significant causes of morbidity and mortality, increasingly relevant as PLWH age. Alcohol use is common among PLWH and known to affect bone health. The association between alcohol use and changes in BMD among PLWH is not well understood. METHODS: We conducted a 3.5-year prospective cohort study of 250 PLWH with substance use disorder or ever injection drug use...
June 6, 2018: Alcoholism, Clinical and Experimental Research
https://www.readbyqxmd.com/read/29871548/antenatal-synthetic-glucocorticoid-exposure-at-human-therapeutic-equivalent-doses-predisposes-middle-age-male-offspring-baboons-to-an-obese-phenotype-that-emerges-with-aging
#8
Hillary F Huber, Anderson H Kuo, Cun Li, Susan L Jenkins, Kenneth G Gerow, Geoffrey D Clarke, Peter W Nathanielsz
INTRODUCTION: Women threatening premature delivery receive synthetic glucocorticoids (sGC) to accelerate fetal lung maturation, reducing neonatal mortality and morbidity. Few investigations have explored potential long-term offspring side effects. We previously reported increased pericardial fat and liver lipids in 10-year-old (human equivalent 40 years) male baboons exposed to 3 antenatal sGC courses. We hypothesized middle-aged sGC male offspring show obesity-related morphometric changes...
January 1, 2018: Reproductive Sciences
https://www.readbyqxmd.com/read/29871372/cooled-radiofrequency-neurotomy-of-the-articular-sensory-branches-of-the-obturator-and-femoral-nerves-combined-approach-using-fluoroscopy-and-ultrasound-guidance-technical-report-and-observational-study-on-safety-and-efficacy
#9
Leonardo Kapural, Suneil Jolly, Joao Mantoan, Harish Badhey, Ty Ptacek
BACKGROUND: Chronic hip joint pain is a common condition with an estimated prevalence of 7% in men and 10% in women, in a population sample aged over 45. Conservative treatment can include physical therapy, weight loss, a variety of pharmacologic agents ranging from nonsteroidal antiinflammatory drugs (NSAIDS) to opioids, and intraarticular injections with various substances. Definitive treatment of hip pain, however, has primarily centered on hip arthroplasty. OBJECTIVE: We describe a novel anterior approach to cooled radiofrequency (RF) hip denervation under combined ultrasound (US) and fluoroscopy guidance to avoid the neurovascular femoral bundle and reach proper landmarks...
May 2018: Pain Physician
https://www.readbyqxmd.com/read/29803784/injectable-nanocomposite-analgesic-delivery-system-for-musculoskeletal-pain-management
#10
Manakamana Khanal, Shalini V Gohil, Emmanuel Kuyinu, Ho-Man Kan, Brittany E Knight, Kyle M Baumbauer, Kevin W-H Lo, Joseph Walker, Cato T Laurencin, Lakshmi S Nair
Musculoskeletal pain is a major health issue which results from surgical procedures (i.e. total knee and/ or hip replacements and rotator cuff repairs), as well as from non-surgical conditions (i.e. sympathetically-mediated pain syndrome and occipital neuralgia). Local anesthetics, opioids or corticosteroids are currently used for the pain management of musculoskeletal conditions. Even though local anesthetics are highly preferred, the need for multiple administration presents significant disadvantages. Development of unique delivery systems that can deliver local anesthetics at the injection site for prolonged time could significantly enhance the therapeutic efficacy and patient comfort...
May 24, 2018: Acta Biomaterialia
https://www.readbyqxmd.com/read/29796764/history-of-concentrated-or-expanded-mesenchymal-stem-cells-for-hip-osteonecrosis-is-there-a-target-number-for-osteonecrosis-repair
#11
REVIEW
Philippe Hernigou, Gilles Guerin, Yasuhiro Homma, Arnaud Dubory, Nathalie Chevallier, Hélène Rouard, Charles Henri Flouzat Lachaniette
PURPOSE: Despite multiple possible treatments, the risk of collapse remains the main problem of osteonecrosis. Heart failure (HF). In an effort to address the reverse this issue, curative strategies with regenerative medicine are increasingly being considered. The aim of this technology is to halt or reverse progression of the disease to collapse. MATERIAL AND METHODS: The pioneering report by Hernigou published in 2002 was the first pilot study suggesting that injection of bone marrow stem cells was a safe approach able to improve osteonecrosis in patients with early stages...
May 24, 2018: International Orthopaedics
https://www.readbyqxmd.com/read/29794280/repetitive-nerve-block-for-neuropathic-pain-management-a-case-report
#12
Zoher Naja, Ahmad Salah Naja, Omar Rajab, Anas Mugharbil, Abdul Rahman Shatila, Janah Al Hassan
Schwannoma is a common neoplasm in the peripheral and central nervous systems. Sciatic nerve schwanommas are rare. We report the case of a 50-year-old woman who was referred for treatment of persistent neuropathic pain in the left lower limb after resection of a schwannoma on the left S1 nerve root. The patient's history goes back when she was 27 years old and started to have electric-like pain in her lower left limb upon intercourse. Examination revealed a left ovarian cyst which was surgically removed. Her pain persisted despite taking nonsteroidal anti inflammatory drugs (NSAIDs)...
January 26, 2018: Scandinavian Journal of Pain
https://www.readbyqxmd.com/read/29757716/us-assessment-of-sports-related-hip-injuries
#13
Eugen Lungu, Johan Michaud, Nathalie J Bureau
Traumatic and overuse hip injuries occur frequently in amateur and professional athletes. After clinical assessment, imaging plays an important role in diagnosis and in defining care management of these injuries. Ultrasonography (US) is being increasingly used in assessment of hip injuries because of the wide availability of US machines, the lower cost, and the unique real-time imaging capability, which allows both static and dynamic evaluation as well as guidance of point-of-care interventions such as fluid aspiration and steroid injection...
May 2018: Radiographics: a Review Publication of the Radiological Society of North America, Inc
https://www.readbyqxmd.com/read/29744647/cell-therapy-versus-simultaneous-contralateral-decompression-in-symptomatic-corticosteroid-osteonecrosis-a-thirty-year-follow-up-prospective-randomized-study-of-one-hundred-and-twenty-five-adult-patients
#14
Philippe Hernigou, Arnaud Dubory, Yasuhiro Homma, Isaac Guissou, Charles Henri Flouzat Lachaniette, Nathalie Chevallier, Hélène Rouard
PURPOSE: Symptomatic osteonecrosis related to corticosteroids has a high risk of progression to collapse in absence of treatment. The purposes of this study were to evaluate the results of autologous bone marrow grafting of the symptomatic hip in adult patients with osteonecrosis and to compare the results with core decompression alone in the contralateral symptomatic hip. MATERIALS AND METHODS: A total of 125 consecutive patients (78 males and 47 females) with bilateral osteonecrosis (ON) and who had both hips symptomatic and at the same stage on each side (stage I or II) were included in this study from 1988 to 1998...
May 9, 2018: International Orthopaedics
https://www.readbyqxmd.com/read/29721359/acute-cauda-equina-syndrome-following-orthopedic-procedures-as-a-result-of-epidural-anesthesia
#15
Lisa B E Shields, Vasudeva G Iyer, Yi Ping Zhang, Christopher B Shields
Background: Cauda equina syndrome (CES) is a rare complication of spinal or epidural anesthesia. It is attributed to direct mechanical injury to the spinal roots of the cauda equina that may result in saddle anesthesia and paraplegia with bowel and bladder dysfunction. Case Description: The first patient underwent a hip replacement and received 5 mL of 1% lidocaine epidural anesthesia. Postoperatively, when the patient developed an acute CES, the lumbar magnetic resonance imaging (MRI) scan demonstrated clumping/posterior displacement of nerve roots of the cauda equina consistent with adhesive arachnoiditis attributed to the patient's previous L4-L5 lumbar decompression/fusion...
2018: Surgical Neurology International
https://www.readbyqxmd.com/read/29720374/education-plus-exercise-versus-corticosteroid-injection-use-versus-a-wait-and-see-approach-on-global-outcome-and-pain-from-gluteal-tendinopathy-prospective-single-blinded-randomised-clinical-trial
#16
Rebecca Mellor, Kim Bennell, Alison Grimaldi, Philippa Nicolson, Jessica Kasza, Paul Hodges, Henry Wajswelner, Bill Vicenzino
OBJECTIVE: To compare the effects of a programme of load management education plus exercise, corticosteroid injection use, and no treatment on pain and global improvement in individuals with gluteal tendinopathy. DESIGN: Prospective, three arm, single blinded, randomised clinical trial. SETTING: Brisbane and Melbourne, Australia. PARTICIPANTS: Individuals aged 35-70 years, with lateral hip pain for more than three months, at least 4/10 on the pain numerical rating scale, and gluteal tendinopathy confirmed by clinical diagnosis and magnetic resonance imaging; and with no corticosteroid injection use in previous 12 months, current physiotherapy, total hip replacement, or neurological conditions...
May 2, 2018: BMJ: British Medical Journal
https://www.readbyqxmd.com/read/29696307/stem-cell-therapy-in-bilateral-osteonecrosis-computer-assisted-surgery-versus-conventional-fluoroscopic-technique-on-the-contralateral-side
#17
Philippe Hernigou, Benjamin Thiebaut, Victor Housset, Claire Bastard, Yasuhiro Homma, Younes Chaib, Charles Henri Flouzat Lachaniette
PURPOSE: Surgical management of osteonecrosis with core decompression with stem cell therapy is a new procedure. The technique is performed with fluoroscopic guidance. This study attempts to determine if computer-navigated technique can improve the procedure. METHODS: Thirty consecutive patients with bilateral symptomatic osteonecrosis without collapse were included in this study during the year 2011. A prospective, randomized, and controlled study was conducted on 60 hips (bilateral osteonecrosis) using conventional fluoroscopy technique on one side and computer-based navigation on the contralateral side...
April 26, 2018: International Orthopaedics
https://www.readbyqxmd.com/read/29694645/effects-of-ultrasound-guided-botulinum-toxin-type-a-injections-with-a-specific-approach-in-spastic-cerebral-palsy
#18
Raikan Büyükavcı, Mehmet Akif Büyükavcı
The aim of this study was to detect effects of ultrasound-guided botulinum toxin type-A (US-guided BoNT-A) injections prepared according to lower extremity innervation zones on spasticity and motor function in 3-16 years children with diplegic and hemiplegic spastic cerebral palsy. This study included 25 patients between 3 and 16 years of age who admitted to our clinic in 2017, were being followed in our clinic with a diagnosis of cerebral palsy, had BoNT-A injections due to lower extremity spasticity. The US-guided BoNT-A injections were administered into the spastic muscles using a specific approach according to innervation zones of muscle...
April 24, 2018: Acta Neurologica Belgica
https://www.readbyqxmd.com/read/29675502/survival-analysis-after-core-decompression-in-association-with-platelet-rich-plasma-mesenchymal-stem-cells-and-synthetic-bone-graft-in-patients-with-osteonecrosis-of-the-femoral-head
#19
Riccardo D'Ambrosi, Elena Biancardi, Giulia Massari, Vincenza Ragone, Renato Mario Facchini
Purpose  The aim of this study was to report the rate of survivorship in patients with osteonecrosis of the femoral head treated with core decompression in association with mesenchymal stem cells (MSCs) implantation, platelet-rich plasma (PRP) injection, and synthetic bone graft. Methods  We evaluated 24 hips in 16 patients, according to Ficat classification, treated by core decompression, injection of PRP and MSCs, and backfilling of the core tract with synthetic bone graft. Survivorship was estimated using Kaplan-Meier curves...
March 2018: Joints
https://www.readbyqxmd.com/read/29671497/osteoarthritis-rapid-evidence-review
#20
Mark H Ebell
Osteoarthritis (OA) should be suspected in patients with pain in the fingers, shoulders, hips, knees, or ankles, especially if they are older than 40 years. Patients older than 50 years who have joint pain, minimal morning stiffness, and functional impairment likely have OA. Radiography can confirm the diagnosis and may be helpful before surgical referral, but findings generally do not correlate well with symptoms. Exercise, physical therapy, knee taping, and tai chi are beneficial for knee OA. Medical therapy provides modest benefits in pain reduction and functional improvement; however, nonsteroidal anti-inflammatory drugs, tramadol, and other opioids have significant potential harms...
April 15, 2018: American Family Physician
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