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https://www.readbyqxmd.com/read/28566525/supplementation-with-rrr-or-all-rac-%C3%AE-tocopherol-differentially-affects-the-%C3%AE-tocopherol-stereoisomer-profile-in-the-milk-and-plasma-of-lactating-women
#1
Shashank Gaur, Matthew J Kuchan, Chron-Si Lai, Soren K Jensen, Christina L Sherry
Background: The naturally occurring α-tocopherol stereoisomer RRR-α-tocopherol is known to be more bioactive than synthetic α-tocopherol (all-rac-α-tocopherol). However, the influence of this difference on the α-tocopherol stereoisomer profile of human milk is not understood.Objective: We investigated whether supplemental RRR-α-tocopherol or all-rac-α-tocopherol differentially affected the distribution of α-tocopherol stereoisomers in milk and plasma from lactating women.Methods: Eighty-nine lactating women aged 19-40 y and with a body mass index (in kg/m(2)) ≤30 were randomly assigned at 4-6 wk postpartum to receive a daily supplement containing 45...
May 31, 2017: Journal of Nutrition
https://www.readbyqxmd.com/read/28544188/novel-tool-for-deprescribing-in-chronic-patients-with-multimorbidity-list-of-evidence-based-deprescribing-for-chronic-patients-criteria
#2
Aitana Rodríguez-Pérez, Eva Rocío Alfaro-Lara, Sandra Albiñana-Perez, María Dolores Nieto-Martín, Jesús Díez-Manglano, Concepción Pérez-Guerrero, Bernardo Santos-Ramos
AIM: To create a tool to identify drugs and clinical situations that offers an opportunity of deprescribing in patients with multimorbidity. METHODS: A literature review completed with electronic brainstorming, and subsequently, a panel of experts using the Delphi methodology were applied. The experts assessed the criteria identified in the literature and brainstorming as possible situations for deprescribing. They were also asked to assess the influence of life prognosis in each criterion...
May 21, 2017: Geriatrics & Gerontology International
https://www.readbyqxmd.com/read/28525708/affinity-based-assembly-of-peptides-on-plasmonic-nanoparticles-delivered-intracellularly-with-light-activated-control
#3
Demosthenes P Morales, William Wonderly, Xiao Huang, Meghan McAdams, Amanda Chron, Norbert O Reich
We report a universal strategy for functionalizing near-infrared light-responsive nanocarriers with both a peptide "cargo" and an orthogonal cell-penetrating peptide. Modularity of both the cargo and internalization peptide attachment are an important feature of these materials relying on the robust affinity of polyhistidine tags to nitrilotriacetic acid in the presence of nickel as well as the affinity of biotin labeled peptides to streptavidin. Attachment to the gold surface uses thiol labeled scaffolds terminated with the affinity partner...
May 19, 2017: Bioconjugate Chemistry
https://www.readbyqxmd.com/read/28434540/an-updated-age-for-the-xujiayao-hominin-from-the-nihewan-basin-north-china-implications-for-middle-pleistocene-human-evolution-in-east-asia
#4
Hong Ao, Chun-Ru Liu, Andrew P Roberts, Peng Zhang, Xinwen Xu
The Xujiayao site in the Nihewan Basin (North China) is one of the most important Paleolithic sites in East Asia. Twenty Homo fossils, which were previously assigned to an archaic Homo sapiens group, have been excavated along with more than 30,000 lithic artifacts and ∼5000 mammalian fossil specimens. Dating of the Xujiayao hominin has been pursued since its excavation in the 1970s, but its age has remained controversial because of limitations of the dating techniques that have been applied to available materials...
May 2017: Journal of Human Evolution
https://www.readbyqxmd.com/read/28163989/authigenic-10-be-9-be-ratio-signatures-of-the-cosmogenic-nuclide-production-linked-to-geomagnetic-dipole-moment-variation-since-the-brunhes-matuyama-boundary
#5
Quentin Simon, Nicolas Thouveny, Didier L Bourlès, Jean-Pierre Valet, Franck Bassinot, Lucie Ménabréaz, Valéry Guillou, Sandrine Choy, Luc Beaufort
Geomagnetic dipole moment variations associated with polarity reversals and excursions are expressed by large changes of the cosmogenic nuclide beryllium-10 ((10)Be) production rates. Authigenic (10)Be/(9)Be ratios (proxy of atmospheric (10)Be production) from oceanic cores therefore complete the classical information derived from relative paleointensity (RPI) records. This study presents new authigenic (10)Be/(9)Be ratio results obtained from cores MD05-2920 and MD05-2930 collected in the west equatorial Pacific Ocean...
November 2016: Journal of Geophysical Research. Solid Earth
https://www.readbyqxmd.com/read/28151460/advancing-nursing-practice-the-emergence-of-the-role-of-advanced-practice-nurse-in-saudi-arabia
#6
Denise Hibbert, Ahmad E Aboshaiqah, Kathy A Sienko, Debra Forestell, Adel W Harb, Shadia A Yousuf, Patricia W Kelley, Patricia F Brennan, Laura Serrant, Alison Leary
BACKGROUND: The roots of advanced practice nursing (APN) can be traced back to the 1890s, but the nurse practitioner (NP) emerged in Western countries during the 1960s in response to the unmet healthcare needs of populations in rural areas. These early NPs utilized the medical model of care to assess, diagnose and treat. Nursing has since grown as a profession, with its own unique and distinguishable, holistic, science-based knowledge, which is complementary within the multidisciplinary team...
January 2017: Annals of Saudi Medicine
https://www.readbyqxmd.com/read/27672632/comparison-of-brain-development-in-sow-reared-and-artificially-reared-piglets
#7
Reeba M Jacob, Austin T Mudd, Lindsey S Alexander, Chron-Si Lai, Ryan N Dilger
INTRODUCTION: Provision of adequate nutrients is critical for proper growth and development of the neonate, yet the impact of breastfeeding versus formula feeding on neural maturation has to be fully determined. Using the piglet as a model for the human infant, our objective was to compare neurodevelopment of piglets that were either sow-reared (SR) or artificially reared (AR) in an artificial setting. METHODS: Over a 25-day feeding study, piglets (1.5 ± 0...
2016: Frontiers in Pediatrics
https://www.readbyqxmd.com/read/27620327/evaluating-chronic-suicide-risk-with-the-personality-assessment-inventory-development-and-initial-validation-of-the-chronic-suicide-risk-index-s_chron
#8
Samuel Justin Sinclair, Michael J Roche, Christina Temes, Christina Massey, Wei-Jean Chung, Michelle Stein, Laura Richardson, Mark Blais
The current study sought to develop and validate a new measure of chronic suicide risk (the S_Chron) from the Personality Assessment Inventory in a mixed sample of psychiatric inpatients and outpatients. In an initial development sample (N=397), hierarchical logistic regression identified six PAI variables uniquely associated with multiple versus single/no prior suicide attempts after controlling for sample demographics: Negative Impression Management, Situational Stress, Mania - Grandiosity, Borderline - Negative Relationships, Borderline - Self-Harm, and Antisocial Behaviors...
November 30, 2016: Psychiatry Research
https://www.readbyqxmd.com/read/27572303/geomagnetic-reversal-rates-following-palaeozoic-superchrons-have-a-fast-restart-mechanism
#9
Mark W Hounslow
Long intervals of single geomagnetic polarity (superchrons) reflect geodynamo processes, driven by core-mantle boundary interactions; however, it is not clear what initiates the start and end of superchrons, other than superchrons probably reflect lower heat flow across the core-mantle boundary compared with adjacent intervals. Here geomagnetic polarity timescales, with confidence intervals, are constructed before and following the reverse polarity Kiaman (Carboniferous-Permian) and Moyero (Ordovician) superchrons, providing a window into the geodynamo processes...
August 30, 2016: Nature Communications
https://www.readbyqxmd.com/read/27088019/adalimumab-another-medication-related-to-osteonecrosis-of-the-jaws
#10
Andrea Cassoni, Umberto Romeo, Valentina Terenzi, Marco Della Monaca, Oriana Rajabtork Zadeh, Ingrid Raponi, Maria Teresa Fadda, Antonella Polimeni, Valentino Valentini
Objective. The acronym MRONJ has been created in order to identify "Medication-Related Osteonecrosis of the Jaw," observed after the use of Bisphosphonates, RANK ligand inhibitor, and antiangiogenic medications. Only a case of osteonecrosis of the jaw in a Chron's disease patient following a course of Bisphosphonate and Adalimumab therapy has been recently described, so that it has been supposed that also this medication could promote manifestation of osteonecrosis. Clinical Case. On August, 2014, a 63-year-old female with a history of idiopathic arthritis treated with medical treatment with Adalimumab from 2010 to 2013 presented referring pain in the right mandible...
2016: Case Reports in Dentistry
https://www.readbyqxmd.com/read/26997549/palaeomagnetism-of-the-upper-miocene-lower-pliocene-lavas-from-the-east-carpathians-contribution-to-the-paleosecular-variation-of-geomagnetic-field
#11
Mădălina Vişan, Cristian G Panaiotu, Cristian Necula, Anca Dumitru
Investigations of the paleosecular variation of the geomagnetic field on geological timescales depend on globally distributed data sets from lava flows. We report new paleomagnetic results from lava flows of the East Carpathian Mountains (23.6°E, 46.4°N) erupted between 4 and 6 Ma. The average virtual geomagnetic pole position (76 sites) includes the North Geographic Pole and the dispersion of virtual geomagnetic poles is in general agreement with the data of the Time Averaged geomagnetic Field Initiative...
2016: Scientific Reports
https://www.readbyqxmd.com/read/26939307/clinical-characteristics-and-treatment-of-melkersson-rosenthal-syndrome-overview-of-six-patients
#12
Sanvila Rašković, Jasna Bolpacić, Aleksandra Perić Popadić, Žikica Jovicić, Rada Mišković, Mirjana Bogić
INTRODUCTION: Melkersson-Rosenthal syndrome is a rare disease of unknown etiology. Histopathologically, it presents as granulomatous cheilitis. From laboratory aspect, it is a nonspecific, differential diagnostically and therapeutically complex condition. CASE REPORT: This is a report of six cases treated at the Department of Allergology and Immunology of the Clinical Center of Serbia, who had presented with the referral diagnosis of recurring or persistent lip edema, and who were diagnosed with Melkersson-Rosenthal syndrome upon detailed evaluation...
November 2015: Medicinski Pregled
https://www.readbyqxmd.com/read/26533498/optimal-treatment-of-chron-s-disease-with-biologicals-in-a-western-balkan-country-estimates-of-cost-utility-by-markov-model-and-budget-impact-analysis
#13
S Jankovic, L Djakovic, R Sujic, M Kostic
No abstract text is available yet for this article.
November 2015: Value in Health: the Journal of the International Society for Pharmacoeconomics and Outcomes Research
https://www.readbyqxmd.com/read/25597365/the-experiences-of-russian-speaking-migrants-in-primary-care-consultations
#14
Viktoria Bachmann, Michael Völkner, Stefan Bösnerr, Norbert Donner-Banzhoff
BACKGROUND: Some three million Russian-speaking immigrants from the former Soviet Union live in Germany today. Many of them underwent a different kind of medical socialization than the indigenous population, but the experiences and expectations of this group of patients have hardly been studied to date. METHODS: In a qualitative study, 24 chronically ill native Germans and 25 chronically ill Russian-speaking immigrants were recruited via notices, through their primary care physicians, and by word of mouth and underwent a semistructured interview in their mother tongue (German or Russian) about their experiences with their primary care physicians...
December 22, 2014: Deutsches Ärzteblatt International
https://www.readbyqxmd.com/read/25346193/intestinal-tuberculosis-in-a-child-living-in-a-country-with-a-low-incidence-of-tuberculosis-a-case-report
#15
Piera Dones, Maria Di Gangi, Maria Concetta Failla, Selene Genova, Caterina Giannitto, Giovanni Corsello, Nicola Principi, Susanna Esposito
BACKGROUND: Relatively common in adults, intestinal tuberculosis is considered rare in children and adolescents. The protean manifestations of intestinal tuberculosis mean that the diagnosis is often delayed (sometimes even for years), thus leading to increased mortality and unnecessary surgery. The main diagnostic dilemma is to differentiate intestinal tuberculosis and Crohn's disease because a misdiagnosis can have dramatic consequences. CASE PRESENTATION: A 13-year-old Caucasian, Italian female adolescent attended the Emergency Department complaining of abdominal pain, a fever of up to 38 °C, night sweats, diarrhea with blood in stool, and a weight loss of about three kilograms over the previous two months...
October 27, 2014: BMC Research Notes
https://www.readbyqxmd.com/read/25334157/aspergillus-empyema-presented-with-hydropneumothorax
#16
Taha Bekci, Mustafa Calik, Suleyman Akin, Saniye Calik, Hidir Esme
SESSION TITLE: Infectious Disease Global Case ReportsSESSION TYPE: Global Case ReportPRESENTED ON: Tuesday, October 28, 2014 at 01:30 PM - 02:30 PMINTRODUCTION: Aspergillus species is one of the commonest causes of fungal infections.[1] . The aspergillus empyema is a rare clinical entity. Pleural aspergillosis is not characteristically associated with pulmonary aspergillosis in either its allergic, bronchopneumonic, or intracavitary forms [2] Empyemas are rare presentations of fungal infection...
October 1, 2014: Chest
https://www.readbyqxmd.com/read/24951994/-home-parenteral-nutrition-satisfaction-of-patients-and-their-caregivers-with-nutrition-unit-and-pharmacy-service
#17
Paula Arrabal Durán, Rosa María Romero Jiménez, Cristina Cuerda Compes, Miguel Camblor Álvarez, Irene Bretón Lesmes, Ana De Lorenzo Pinto, Silvia Buendía Bravo, Laura Frías Soriano, Pilar García Peris, María Sanjurjo Sáez
INTRODUCTION: Home Parenteral Nutrition (HPN) is a practice in continually growing by the significant advantages involved for the patient and the healthcare system. Today, in the investigation of health outcomes is essential to assess the patient s opinion. Among the measures focused on patients with HPN, several studies about quality of life have been done, but the degree of satisfaction with this treatment modality has not been evaluated. OBJECTIVE: To evaluate the degree of satisfacion of patients and their caregivers receiving HPN with doctors, pharmacists and nurses in a hospital...
2014: Nutrición Hospitalaria: Organo Oficial de la Sociedad Española de Nutrición Parenteral y Enteral
https://www.readbyqxmd.com/read/24843149/age-constraints-on-the-dispersal-of-dinosaurs-in-the-late-triassic-from-magnetochronology-of-the-los-colorados-formation-argentina
#18
Dennis V Kent, Paula Santi Malnis, Carina E Colombi, Oscar A Alcober, Ricardo N Martínez
A measured magnetozone sequence defined by 24 sampling sites with normal polarity and 28 sites with reverse polarity characteristic magnetizations was established for the heretofore poorly age-constrained Los Colorados Formation and its dinosaur-bearing vertebrate fauna in the Ischigualasto-Villa Union continental rift basin of Argentina. The polarity pattern in this ∼600-m-thick red-bed section can be correlated to Chrons E7r to E15n of the Newark astrochronological polarity time scale. This represents a time interval from 227 to 213 Ma, indicating that the Los Colorados Formation is predominantly Norian in age, ending more than 11 My before the onset of the Jurassic...
June 3, 2014: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/24790722/unifocal-orofacial-granulomatosis-in-retromolar-mucosa-surgical-treatment-with-er-cr-ysgg-laser
#19
Pablo Castelo-Baz, Juan M Seoane-Romero, Lucía García-Caballero, José M Suárez-Peñaranda, María A Romero-Méndez, Pablo Varela-Centelles
Orofacial granulomatosis is defined by permanent or recurrent swelling of orofacial tissues with different multiform and multifocal clinical patterns. An 11-year old boy presented with a 2-month history of mucosa enlargement. Intraoral examination revealed an erythematous, polylobulated, exophytic lesion with a smooth surface located in retromolar mucosa, non-tender and non-infiltratated to palpation. The diagnosis was inflammatory lesion compatible with pyogenic granuloma and laser excision was decided. Haematological parameters were within normal range, as well as chest Xrays...
April 2014: Journal of Clinical and Experimental Dentistry
https://www.readbyqxmd.com/read/24485349/luminescence-dating-and-palaeomagnetic-age-constraint-on-hominins-from-sima-de-los-huesos-atapuerca-spain
#20
Lee J Arnold, Martina Demuro, Josep M Parés, Juan Luis Arsuaga, Arantza Aranburu, José María Bermúdez de Castro, Eudald Carbonell
Establishing a reliable chronology on the extensive hominin remains at Sima de los Huesos is critical for an improved understanding of the complex evolutionary histories and phylogenetic relationships of the European Middle Pleistocene hominin record. In this study, we use a combination of 'extended-range' luminescence dating techniques and palaeomagnetism to provide new age constraint on sedimentary infills that are unambiguously associated with the Sima fossil assemblage. Post-infrared-infrared stimulated luminescence (pIR-IR) dating of K-feldspars and thermally transferred optically stimulated luminescence (TT-OSL) dating of individual quartz grains provide weighted mean ages of 433 ± 15 ka (thousands of years) and 416 ± 19 ka, respectively, for allochthonous sedimentary horizons overlying the hominin-bearing clay breccia...
February 2014: Journal of Human Evolution
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