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Werner erhard

Werner Ruppitsch, Rita Prager, Sven Halbedel, Patrick Hyden, Ariane Pietzka, Steliana Huhulescu, Dorothee Lohr, Katharina Schönberger, Elisabeth Aichinger, Anja Hauri, Klaus Stark, Sabine Vygen, Erhard Tietze, Franz Allerberger, Hendrik Wilking
Listeriosis patient isolates in Germany have shown a new identical pulsed-field gel electrophoresis (PFGE) pattern since 2012 (n = 66). Almost all isolates (Listeria monocytogenes serotype 1/2a) belonged to cases living in southern Germany, indicating an outbreak with a so far unknown source. Case numbers in 2015 are high (n = 28). No outbreak cases outside Germany have been reported. Next generation sequencing revealed the unique cluster type CT1248 and confirmed the outbreak. Investigations into the source are ongoing...
2015: Euro Surveillance: Bulletin Européen sur les Maladies Transmissibles, European Communicable Disease Bulletin
Dominik P Erhard, Florian Richter, Christian B A Bartz, Hans-Werner Schmidt
In view of the increasing significance of technology-driven devices such as microelectromechanical systems, energy-harvesting devices, and organic field effect transistors, polymer electret materials with durable electret performance at elevated temperatures become more and more important. However, typical polymer electret materials lose their performance at elevated temperatures. To provide polymer materials with improved electret performance over a broad temperature range, a series of aromatic polyimides with different degree of fluorosubstitution is presented...
March 2015: Macromolecular Rapid Communications
D Werner, E Mörschel, R Kort, R B Mellor, S Bassarab
In nodules of Glycine max cv. Mandarin infected with a nod (+)fix(-) mutant of Rhizobium japonicum (RH 31-Marburg), lysis of bacteroids was observed 20 d after infection, but occurred in the region around the host cell nucleus, where lytic compartments were formed. Bacteroids, and peribacteroid membranes in other parts of the host cell remained stable until senescence (40d after infection). With two other nod(+) fix(-) mutants of R. japonicum either stable bacteroids and peribacteroid membranes were observed throughout the cell (strain 61-A-165) or a rapid degeneration of bacteroids without an apparent lysis (strain USDA 24) occurred...
September 1984: Planta
Grace M S Yip, Zi-Wei Chen, Christopher J Edge, Edward H Smith, Robert Dickinson, Erhard Hohenester, R Reid Townsend, Karoline Fuchs, Werner Sieghart, Alex S Evers, Nicholas P Franks
Propofol is the most important intravenous general anesthetic in current clinical use. It acts by potentiating GABAA (γ-aminobutyric acid type A) receptors, but where it binds to this receptor is not known and has been a matter of some debate. We synthesized a new propofol analog photolabeling reagent whose biological activity is very similar to that of propofol. We confirmed that this reagent labeled known propofol binding sites in human serum albumin that have been identified using X-ray crystallography...
November 2013: Nature Chemical Biology
Erhard F Kaleta, Ortrud Werner, Yvonne Hemberger
Meat and skin from farmed ostriches are valuable products for European consumers. The EU regulations require that ostrich products deamed for export need to come from ostriches that are free of antibodies against Newcastle disease virus (avian paramxovirus type 1, aPMV-1). After the detection of antibodies against aPMV-1 in one of five ostrich farms in Namibia, attempts were made to isolate the causative virus. No aPMV-1 but an avian paramyxovirus type 3 (aPMV-3) was isolated from five pharyngeal/cloacal swabs of clinically healthy farmed Namibian ostriches...
March 2010: Berliner und Münchener Tierärztliche Wochenschrift
Massimo Santini, Maurizio Russo, Gianluca Botto, Maurizio Lunati, Alessandro Proclemer, Boris Schmidt, Ali Erdogan, Erhard Helmling, Werner Rauhe, Martin Desaga, Elisabetta Santi, Marc Messier, Giuseppe Boriani
AIMS: To evaluate clinical and arrhythmic outcomes in post-infarction cardiomyopathy patients implanted with a defibrillator (ICD) for primary prevention of sudden death. METHODS AND RESULTS: The SEARCH-MI registry is a European multi-centre, prospective, observational study enrolling patients after myocardial infarction, chronic left ventricular dysfunction and an ICD implanted for primary prevention of sudden death. Data on 556 patients with at least one recorded follow-up are presented...
April 2009: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
Carsten Horn, Stefan Jenewein, Britta Tschapek, Werner Bouschen, Sabine Metzger, Erhard Bremer, Lutz Schmitt
The ABC transporter (ATP-binding-cassette transporter) OpuA is one of five membrane transport systems in Bacillus subtilis that mediate osmoprotection by importing compatible solutes. Just like all bacterial and archaeal ABC transporters that catalyse the import of substrates, OpuA (where Opu is osmoprotectant uptake) is composed of an ATPase subunit (OpuAA), a transmembrane subunit (OpuAB) and an extracellular substrate-binding protein (OpuAC). In contrast with many well-known ABC-ATPases, OpuAA is composed not only of a catalytic and a helical domain but also of an accessory domain located at its C-terminus...
June 1, 2008: Biochemical Journal
Udo Gross, Stephan Rüdiger, Erhard Kemnitz, Klaus-Werner Brzezinka, Sanghamitra Mukhopadhyay, Christine Bailey, Adrian Wander, Nicholas Harrison
The vibrational modes of three solid AlF3 phases (alpha, beta, and amorphous high surface area AlF3) are investigated. Calculations have been performed using hybrid exchange correlation functionals to determine the equilibrium geometries and Gamma-point phonon frequencies for the alpha-AlF3 and beta-AlF3 phases. The calculated optical modes are in excellent agreement with experiment. The IR absorption of the amorphous, glasslike high surface area (HS)-AlF3 is also discussed. Deconvolution of the broad envelope of IR stretches and bending vibrations identifies the components of the observed broad band...
July 5, 2007: Journal of Physical Chemistry. A
Hubert Schrezenmeier, Gabriele Walther-Wenke, Thomas H Müller, Franz Weinauer, Adelheid Younis, Tim Holland-Letz, Gabriele Geis, Jens Asmus, Ursula Bauerfeind, Jürgen Burkhart, Robert Deitenbeck, Elisabeth Förstemann, Wolfgang Gebauer, Britta Höchsmann, Apostolos Karakassopoulos, Ute-Maja Liebscher, Werner Sänger, Michael Schmidt, Friedrich Schunter, Walid Sireis, Erhard Seifried
BACKGROUND: The GERMS Group initiated a prospective multicenter study to assess prevalence and nature of bacterial contamination of pooled buffy-coat platelet concentrates (PPCs) and apheresis platelet concentrates (APCs) by routine screening with a bacterial culture system. STUDY DESIGN AND METHODS: In nine centers overall, 52,243 platelet (PLT) concentrates (15,198 APCs, 37,045 PPCs) were analyzed by aerobic and anaerobic cultures (BacT/ALERT, bioMérieux). RESULTS: In 135 PLT concentrates (PCs; 0...
April 2007: Transfusion
Daniela V Meisel, Ruth A Byrne, Michael Kuba, Jennifer Mather, Werner Ploberger, Erhard Reschenhofer
Octopus macropus and Octopus vulgaris have overlapping habitats and are exposed to similar temporal changes. Whereas the former species is described as nocturnal in the field, there are conflicting reports about the activity time of the latter one. To compare activity patterns, the authors tested both species in the laboratory. Octopuses were exposed to a light-dark cycle and held under constant dim light for 7 days each. O. macropus showed nocturnal and light-cued activity. According to casual observations, O...
August 2006: Journal of Comparative Psychology
Thomas Dirschka, Hans-Ullrich Schildhaus, Eva Wardelmann, Heinz Werner Seifert, Erhard Bierhoff
No abstract text is available yet for this article.
March 2006: Journal der Deutschen Dermatologischen Gesellschaft, Journal of the German Society of Dermatology: JDDG
Christiane A Kolb, Eva Wirth, Werner M Kaiser, Armin Meister, Markus Riederer, Erhard E Pfündel
The use of chlorophyll fluorescence measurements to noninvasively evaluate degrees of ripeness was investigated in berries at various stages of ripening from two white grapevine cultivars (Vitis vinifera L. Cv. Bacchus and Silvaner). Berries were characterized by diameter, weight, and density and by concentrations of fructose, glucose, sucrose, and total sugars, as well as fructose/glucose ratios, and also by chlorophyll fluorescence at F(0) and F(M) levels and the fluorescence ratio F(V)/F(M). Pearson product moment correlation analysis on data from both cultivars revealed clear negative associations between F(0) and concentrations of fructose, glucose, and total sugars, and fructose/glucose ratios (correlation coefficient < -0...
January 25, 2006: Journal of Agricultural and Food Chemistry
Dorina Ujvári, Eniko Wehmann, Erhard F Kaleta, Ortrud Werner, Vladimir Savić, Eva Nagy, György Czifra, Béla Lomniczi
Partial sequence and residue substitution analyses of the fusion protein gene were performed for 68 strains of avian paramyxovirus type 1 of pigeons (PPMV-1), an antigenic variant of Newcastle disease virus (NDV) of chickens, derived from 16 countries between 1978 and 2002. The majority of isolates clustered into a single genetic lineage, termed VIb/1, within genotype VI of NDV strains of chickens, whereas a small number of isolates that originated in Croatia after 1995, grouped in a highly diverged lineage, termed VIb/2, indicating a separate host-switching event from that of VIb/1 strains...
October 2003: Virus Research
Peter Albers, Roswitha Siener, Sabine Kliesch, Lothar Weissbach, Susanne Krege, Christoph Sparwasser, Harald Schulze, Axel Heidenreich, Werner de Riese, Volker Loy, Erhard Bierhoff, Christian Wittekind, Rolf Fimmers, Michael Hartmann
PURPOSE: To prospectively assess potential risk factors for relapse in clinical stage I nonseminomatous germ cell tumors of the testis (CS I NSGCT). PATIENTS AND METHODS: From September 1996 to May 2002, 200 patients with CS I NSGCT were prospectively assigned to retroperitoneal lymph node dissection (RPLND), and risk factor assessment was performed within a multicenter protocol. One hundred sixty-five patients had an adequate minimum follow-up of 12 months (mean, 34...
April 15, 2003: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
Carina Ittrich, Erhard Deml, Doris Oesterle, Karin Küttler, Werner Mellert, Susanne Brendler-Schwaab, Harald Enzmann, Ludwig Schladt, Peter Bannasch, Thomas Haertel, Oliver Mönnikes, Michael Schwarz, Annette Kopp-Schneider
A rat liver foci bioassay (RLFB) based on an initiation-promotion protocol employing preneoplastic foci of altered hepatocytes (FAH) as an endpoint, was prevalidated in 5 different laboratories. FAH were identified by immunohistochemical demonstration of glutathione-S-transferase (placental form, GSTP) and by staining with hematoxilin/eosin (H&E), and their area fraction was quantified morphometrically. The four model hepatocarcinogens N-nitrosomorpholine, 2-acetylaminofluoren, phenobarbital, and clofibrate were selected according to characteristic differences in their presumed mode of action, and tested in a total of 1,600 male and female rats at 2 different dose levels...
January 2003: Toxicologic Pathology
Burkhard Schlosshauer, Erhard Müller, Bernhard Schröder, Heinrich Planck, Hans-Werner Müller
A micro-structured, biodegradable, semipermeable hollow nerve guide implant was developed to bridge nerve lesions. Quantitative comparison of cell migration and axonal growth using time lapse video recording in vitro revealed that axons grow eight times faster than neuritotrophic Schwann cells migrate. To accelerate regeneration, purified Schwann cells are best injected into nerve guides before implantation. Nerve guides made from resorbable poly-lactide-co-glycolide support Schwann cell attachment, cell survival, and axonal outgrowth in vitro...
February 14, 2003: Brain Research
Andreas Tauch, Susanne Schneiker, Werner Selbitschka, Alfred Pühler, Leo S van Overbeek, Kornelia Smalla, Christopher M Thomas, Mark J Bailey, Larry J Forney, Andrew Weightman, Piotr Ceglowski, Tony Pembroke, Erhard Tietze, Gunnar Schröder, Erich Lanka, Jan Dirk van Elsas
Plasmid pIPO2 is a cryptic, conjugative, broad-host-range plasmid isolated from the wheat rhizosphere. It efficiently self-transfers between alpha, beta and gamma Proteobacteria and has a mobilizing/retromobilizing capacity for IncQ plasmids. The complete nucleotide sequence of pIPO2 is presented on the basis of its mini-Tn5::luxABtet-tagged derivative, pIPO2T. The pIPO2 sequence is 39815 bp long and contains at least 43 complete ORFs. Apart from a suite of ORFs with unknown function, all of the genes carried on pIPO2 are predicted to be involved in plasmid replication, maintenance and conjugative transfer...
June 2002: Microbiology
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