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Brian R Johnson, Gerald T McGinty, Jonathan C Jackson, Thea M Ramsey, Marcus Hjalber, C C Taylor E Hill, Christopher J D'Lauro
No abstract text is available yet for this article.
March 14, 2018: Military Medicine
Peter James Holland, Olivier Codol, Joseph M Galea
Despite increasing interest in the role of reward in motor learning, the underlying mechanisms remain ill-defined. In particular, the contribution of explicit processes to reward-based motor learning is unclear. To address this, we examined subject's (n=30) ability to learn to compensate for a gradually introduced 25⁰ visuomotor rotation with only reward-based feedback (binary success/failure). Only two-thirds of subjects (n=20) were successful at the maximum angle. The remaining subjects initially followed the rotation but after a variable number of trials began to reach at an insufficiently large angle and subsequently returned to near baseline performance (n=10)...
March 14, 2018: Journal of Neurophysiology
William Darrow, Chintan Bhatt, Cassandra Rene, Lakisha Thomas
In January 2016, the first case of mosquito-borne Zika infection in the mainland United States was confirmed in Miami, Florida. The first locally acquired case was reported 6 months later. Local public health and school officials began warning students of the outbreak on their return to the classroom in August 2016. In November-December 2016, we conducted a survey of students attending a large public university in Miami to determine how well informed they were about Zika. A multistage sampling design was used to contact teaching assistants and ask them for help in recruiting their students...
March 1, 2018: Health Education & Behavior: the Official Publication of the Society for Public Health Education
C E Homeyard, E Patelarou
OBJECTIVES: To identify the existing antenatal information provision practices for pregnant women with intellectual disabilities in England. To identify how practices between and within local supervising authorities differed, and if midwives were adapting standard antenatal information for pregnant women with intellectual disabilities, including examples of accessible information being used. STUDY DESIGN: Cross-sectional survey. METHODS: All contact supervisors of midwives from acute trusts with maternity services were accessed via the local supervisor of midwives officers' databases and sent a questionnaire...
March 10, 2018: Public Health
Alison Ward, Kim Alberg Sorensen, Helle Kousgaard, Diana Schack Thoft, Jacqueline Parkes
The provision of lifelong learning for older people is often promoted as a way of engaging socially and maintaining cognitive function. The concept is also used with people with dementia, but is often limited to short-term programmes. Innovative practice from Denmark takes this concept further, offering people with early stage dementia the opportunity to return to school to attend classes in cognitive training, music, art and woodcraft. A pilot study conducted by the school of teaching and communication (Voksenskolen For Undervisning og Kommunikation) offers evidence for the benefits of prolonged educational programmes for people with dementia in maintaining decision-making, cognitive function and social interactions, with limited evidence of the impact on memory...
January 1, 2018: Dementia
Michael Owen Kinney, Stephen J Hunt, Ciaran McKenna
INTRODUCTION: Paramedics are increasingly expected to take on wider roles in the management of epilepsy in the community by making nonconveyance decisions after patients have had seizures. Studies have identified barriers to the successful implementation of this clinical role. We sought to determine levels of confidence, training, perceived barriers, and self-identified learning needs and methods to address these needs regarding seizure management. METHODS AND MATERIALS: A questionnaire was developed by consensus and administered to 63 paramedic and prehospital clinicians at various mandatory training days occurring at the central headquarters of the regional ambulance service in Northern Ireland...
March 7, 2018: Epilepsy & Behavior: E&B
Andreas Liefeith, John Kiely, Dave Collins, Jim Richards
Perhaps as a consequence of increased specialism in training and support, the focus on engendering and maintaining agility as a generic quality has diminished within many contemporary sports performance programmes. Reflecting this, we outline a rationale suggesting that such a decreased focus represents an oversight which may be detrimental to maximising the potential of performers. We present an evidence-based argument that both generic and specific elements of agility performance should be consistently emphasised within long-term performance-training programmes...
March 9, 2018: Journal of Sports Sciences
Elaine C Thompson, Jennifer Krizman, Travis White-Schwoch, Trent Nicol, Cynthia R LaBella, Nina Kraus
OBJECTIVE: Concussions can result in auditory processing deficits even in the absence of hearing loss. In children and adolescents, the extent to which these impairments have functional consequences for everyday listening, such as the ability to understand speech in noisy environments, is unknown. RESEARCH DESIGN: Case-control study. SUBJECTS AND METHODS: Forty youth comprised the participants: 20 had sustained a concussion and were recovering from their injury, and 20 controls had sustained non-concussive orthopaedic (e...
March 8, 2018: Brain Injury: [BI]
Madison B Smith, Tamara G R Macieira, Michael D Bumbach, Susan J Garbutt, Sandra W Citty, Anita Stephen, Margaret Ansell, Toni L Glover, Gail Keenan
OBJECTIVES: To present the findings of a systematic review on the use of simulation-based learning experiences (SBLEs) to teach communication skills to nursing students and clinicians who provide palliative and end-of-life care to patients and their families. BACKGROUND: Palliative care communication skills are fundamental to providing holistic patient care. Since nurses have the greatest amount of direct exposure to patients, building such communication competencies is essential...
January 1, 2018: American Journal of Hospice & Palliative Care
P Scott Pine, Steven P Lund, Jerod R Parsons, Lindsay K Vang, Ashish A Mahabal, Luca Cinquini, Sean C Kelly, Heather Kincaid, Daniel J Crichton, Avrum Spira, Gang Liu, Adam C Gower, Harvey I Pass, Chandra Goparaju, Steven M Dubinett, Kostyantyn Krysan, Sanford A Stass, Debra Kukuruga, Kendall Van Keuren-Jensen, Amanda Courtright-Lim, Karol L Thompson, Barry A Rosenzweig, Lynn Sorbara, Sudhir Srivastava, Marc L Salit
BACKGROUND: The potential utility of microRNA as biomarkers for early detection of cancer and other diseases is being investigated with genome-scale profiling of differentially expressed microRNA. Processes for measurement assurance are critical components of genome-scale measurements. Here, we evaluated the utility of a set of total RNA samples, designed with between-sample differences in the relative abundance of miRNAs, as process controls. RESULTS: Three pure total human RNA samples (brain, liver, and placenta) and two different mixtures of these components were evaluated as measurement assurance control samples on multiple measurement systems at multiple sites and over multiple rounds...
March 6, 2018: BMC Genomics
Felipe Maia de Toledo Piza, Leo Anthony Celi, Rodrigo Octavio Deliberato, Lucas Bulgarelli, Fabricio Rodrigues Torres de Carvalho, Roberto Rabello Filho, Miguel Angel Armengol de La Hoz, Jennifer Cohn Kesselheim
BACKGROUND: Datathons are increasingly organized in the healthcare field. The goal is to assemble people with different backgrounds to work together as a team and engage in clinically relevant research or develop algorithms using health-related datasets. Criteria to assess the return of investment on such events have traditionally included publications produced, patents for prediction, classification, image recognition and other types of software, and start-up companies around the application of machine learning in healthcare...
April 2018: International Journal of Medical Informatics
Lauren C Anderson, Gorica D Petrovich
Persistent responding to food cues may underlie the difficulty to resist palatable foods and to maintain healthy eating habits. Renewal of responding after extinction is a model of persistent food seeking that can be used to study the underlying neural mechanisms. In context-mediated renewal, a return to the context in which the initial cue-food learning occurred induces robust responding to the cues that were extinguished elsewhere. Previous work found sex differences in context-mediated renewal and in the recruitment of the ventromedial prefrontal cortex (vmPFC) during that behavior...
February 26, 2018: Neurobiology of Learning and Memory
Kaneen B Geiger, Linda A LeBlanc, Katie Hubik, Sarah R Jenkins, James E Carr
Discrete-trial teaching is an effective teaching procedure that must be implemented with high integrity to produce optimal learning. Behavioral Skills Training (BST) has proven effective for staff training; however, BST is time and labor intensive. Computer-based instruction (CBI) programs may provide a more efficient and cost-effective alternative to live training if the CBI program is as effective as BST in producing accurate implementation. The current study compared CBI to BST to train novice undergraduate students to conduct discrete-trial teaching...
February 28, 2018: Journal of Applied Behavior Analysis
Angelos-Miltiadis Krypotos, Iris M Engelhard
BACKGROUND AND OBJECTIVES: Excessive avoidance towards non-dangerous cues is a key diagnostic criterion across anxiety-related disorders. Despite current therapies being successful in reducing such avoidance, relapse rates remain high. Based on recent findings, according to which learned fear responses were reduced after the presentation of the fear stimulus with a novel-neutral event (novel-based extinction), we tested whether novel-based extinction could diminish conditioned avoidance...
February 19, 2018: Journal of Behavior Therapy and Experimental Psychiatry
Laurie-Ann Corbin-Berrigan, Kristina Kowalski, Jocelyn Faubert, Brian Christie, Isabelle Gagnon
As mild traumatic brain injury (mTBI) affects hundreds of thousands of children and their families each year, investigation of potential mTBI assessments and treatments is an important research target. Three-dimensional multiple object tracking (3D-MOT), where an individual must allocate attention to moving objects within 3D space, is one potentially promising assessment and treatment tool. To date, no research has looked at 3D-MOT in a pediatric mTBI population. Thus, the aim of this study was to examine 3D-MOT learning in children and youth with and without mTBI...
February 23, 2018: Neuroreport
Hanspeter A Mallot, Stephan Lancier
We present a simple behavioral experiment on human place recognition from a configuration of four visual landmarks. Participants were asked to navigate several paths, all involving a turn at one specific point, and while doing so incidentally learned the position of that turning point. In the test phase, they were asked to return to the turning point in a reduced environment leaving only the four landmarks visible. Results are compared to two versions of a maximum likelihood model of place recognition using either view-based or depth-based cues for place recognition...
February 26, 2018: Biological Cybernetics
Ashley A Blackwell, Mark Banovetz, Qandeel, Ian Q Whishaw, Douglas G Wallace
Arm and hand use by the mouse have been studied in a variety of tasks in order to understand the structure of skilled movements and motor learning, the anatomy and function of neural pathways, and to develop animal models of neurological conditions. The present study describes string-pulling by the mouse, a behavior in which a mouse uses hand-over-hand movements to pull down a string that hangs from the top of a test cage. Mice both spontaneously string-pull and also string-pull to obtain cashew nuts tied to the end of the string as food reward...
February 20, 2018: Behavioural Brain Research
Jan Gryczynski, Robert P Schwartz, Marc J Fishman, Courtney D Nordeck, James Grant, Sanford Nidich, Stuart Rothenberg, Kevin E O'Grady
AIMS: Maladaptive responses to stress are thought to play a role in addiction and relapse. Transcendental Meditation (TM) is a popular meditation technique with promising clinical applications. This study sought to: (a) examine the feasibility of providing TM during AUD treatment; (b) compare outcomes for TM vs. treatment as usual (TAU); and (c) investigate the relationship between TM practice and outcomes. METHODS: Meditation-naïve adults with primary AUD (N = 60; 35% female, 60% white) newly admitted to inpatient treatment were recruited in sequential cohorts (30 receiving TAU and 30 receiving TM training)...
April 2018: Journal of Substance Abuse Treatment
Sarah C Hellewell, Ibolja Cernak
Adaptability to stress is governed by innate resilience, comprised of complex neuroendocrine and immune mechanisms alongside inherited or learned behavioral traits. Based on their capacity to adapt, some people thrive in stressful situations, whereas others experience maladaptation. In our study, we used state-of-the-art tools to assess the resilience level in individuals, as well as their susceptibility to developing military stress-induced behavioral and cognitive deficits. To address this complex question, we tested Canadian Armed Forces (CAF) personnel in three distinct stress environments (baselines): during predeployment training, deployment in Afghanistan, and readjustment upon return to Canada...
February 21, 2018: Journal of Traumatic Stress
Polina Mamoshina, Lucy Ojomoko, Yury Yanovich, Alex Ostrovski, Alex Botezatu, Pavel Prikhodko, Eugene Izumchenko, Alexander Aliper, Konstantin Romantsov, Alexander Zhebrak, Iraneus Obioma Ogu, Alex Zhavoronkov
The increased availability of data and recent advancements in artificial intelligence present the unprecedented opportunities in healthcare and major challenges for the patients, developers, providers and regulators. The novel deep learning and transfer learning techniques are turning any data about the person into medical data transforming simple facial pictures and videos into powerful sources of data for predictive analytics. Presently, the patients do not have control over the access privileges to their medical records and remain unaware of the true value of the data they have...
January 19, 2018: Oncotarget
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