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https://www.readbyqxmd.com/read/29346769/switching-on-depression-and-potentiation-in-the-cerebellum
#1
Andrew R Gallimore, Taegon Kim, Keiko Tanaka-Yamamoto, Erik De Schutter
Long-term depression (LTD) and long-term potentiation (LTP) in the cerebellum are important for motor learning. However, the signaling mechanisms controlling whether LTD or LTP is induced in response to synaptic stimulation remain obscure. Using a unified model of LTD and LTP at the cerebellar parallel fiber-Purkinje cell (PF-PC) synapse, we delineate the coordinated pre- and postsynaptic signaling that determines the direction of plasticity. We show that LTP is the default response to PF stimulation above a well-defined frequency threshold...
January 16, 2018: Cell Reports
https://www.readbyqxmd.com/read/29344399/contested-discourses-and-culture-sensitivity-norwegian-nursing-students-experience-of-clinical-placement-in-nicaragua
#2
Solveig Kirsti Grudt, Hans Hadders
Aim: The purpose of this study was to gain understanding of Norwegian students' practical experience of "culture sensitivity." Design: Using focus-group interviews and individual written assignments, we draw on a Foucauldian-inspired approach to analyse nursing students' narratives about their clinical placement in Nicaragua. Method: Seven third-year bachelor nursing students enrolled in a clinical placement programme on the Caribbean coast in Nicaragua and participated in focus-group interviews...
January 2018: Nursing Open
https://www.readbyqxmd.com/read/29342495/improving-perinatology-residents-skills-in-breaking-bad-news-a-randomized-intervention-study
#3
Maria Silvia Vellutini Setubal, Maria Ângela Reis Goes Monteiro Antonio, Eliana Martorano Amaral, John Boulet
OBJECTIVE:  Breaking bad news (BBN) is particularly difficult in perinatology. Previous research has shown that BBN skills can be learned and improved when taught and practiced. This project evaluated whether a structured training session would enhance perinatology residents' skills in BBN. METHODS:  This was a randomized controlled intervention study with year 1 to 4 Perinatology residents from a medical school in Brazil, during the 2014/15 school year. A total of 61 out of 100 (61%) eligible residents volunteered to a structured training program involving communicating a perinatal loss to a simulated patient (SP) portraying the mother followed by the SP's immediate feedback, both video recorded...
January 17, 2018: Revista Brasileira de Ginecologia e Obstetrícia
https://www.readbyqxmd.com/read/29334751/pursuing-excellence-in-ercp
#4
Jesús García-Cano, Francisco Domper
The term "ERCP cannulation" returns 1,563 items in Pubmed. In 1980 there were 7 papers, and 92 were included in 2015. Any gastroenterologist knows ERCP is often a complex procedure, at times with uncertain results, that unfortunately leads every so often to lawsuits. Most issues derive from attempts at biliary cannulation, despite the improved instruments available since the days of the first sphincterotomy back in 1974. The initial priority goal of ERCP learning is a satisfactory rate of choledochal cannulation...
January 16, 2018: Revista Española de Enfermedades Digestivas
https://www.readbyqxmd.com/read/29333058/acquisition-of-a-socially-learned-tool-use-sequence-in-chimpanzees-implications-for-cumulative-culture
#5
Gillian L Vale, Sarah J Davis, Susan P Lambeth, Steven J Schapiro, Andrew Whiten
Cumulative culture underpins humanity's enormous success as a species. Claims that other animals are incapable of cultural ratcheting are prevalent, but are founded on just a handful of empirical studies. Whether cumulative culture is unique to humans thus remains a controversial and understudied question that has far-reaching implications for our understanding of the evolution of this phenomenon. We investigated whether one of human's two closest living primate relatives, chimpanzees, are capable of a degree of cultural ratcheting by exposing captive populations to a novel juice extraction task...
September 2017: Evolution and Human Behavior: Official Journal of the Human Behavior and Evolution Society
https://www.readbyqxmd.com/read/29327652/acquisition-of-a-mental-strategy-to-control-a-virtual-tail-via-brain-computer-interface
#6
Ayaka Fujisawa, Shoko Kasuga, Takaharu Suzuki, Junichi Ushiba
The objective of the present study was to clarify the variation in and properties of mental images and policies used to regulate specific image selection when learning to control a brain-computer interface. Healthy volunteers performed a reaching task with a virtually generated monkey tail-like object on a computer monitor by regulating event-related desynchronization (ERD) on the buttock area of the sensorimotor cortex as recorded by electroencephalogram (EEG). Participants were instructed to find a free image by which the tail was well controlled...
January 12, 2018: Cognitive Neuroscience
https://www.readbyqxmd.com/read/29320140/using-community-partnerships-to-integrate-health-and-social-services-for-high-need-high-cost-patients
#7
Ruben Amarashingham, Bin Xie, Albert Karam, Nam Nguyen, Bianca Kapoor
Issue: Our health care and social services delivery systems are not well-equipped to effectively manage patients with multiple chronic diseases and complex social needs such as food, housing, or substance abuse services. Community-level efforts have emerged across the nation to integrate the activities of disparate social service organizations with local health care delivery systems. Evidence on the experiences and outcomes of these programs is emerging, and there is much to learn about their approaches and challenges...
January 1, 2018: Issue Brief of the Commonwealth Fund
https://www.readbyqxmd.com/read/29315784/the-prevalence-of-depressive-symptoms-among-arab-adolescents-findings-from-jordan
#8
Latefa Ali Dardas, Susan G Silva, Moria J Smoski, Devon Noonan, Leigh Ann Simmons
BACKGROUND: The lack of research regarding the current profile of adolescent depression in the Arab countries in general, and Jordan in particular, makes it difficult to design, implement, and disseminate effective interventions to improve the prevention, diagnosis, and treatment of adolescent depression in the region. The purpose of this study was to estimate a national prevalence of depressive symptoms among adolescents in Jordan, and to identify characteristics associated with severity of depression...
January 8, 2018: Public Health Nursing
https://www.readbyqxmd.com/read/29315106/zurich-to-berlin-where-are-we-now-with-the-concussion-in-sport-group
#9
Margaret E Pusateri, Brandon J Hockenberry, Christopher A McGrew
The Concussion in Sport Group recently published its highly anticipated fifth consensus statement on sports-related concussion. The latest iteration features a new organizational format-the "11 Rs" and has input from a wider range of health care professionals, organizations, and experts in the field from both the sport concussion area and from related areas outside of sport. The stated objective of this current document is to "build on the principles outlined in previous statements and develop further conceptual understanding of sports-related concussion...
January 2018: Current Sports Medicine Reports
https://www.readbyqxmd.com/read/29314021/greater-reinforcement-rate-during-training-increases-spontaneous-recovery
#10
Eric A Thrailkill, Ryan T Kimball, Michael E Kelley, Andrew R Craig, Christopher A Podlesnik
Spontaneous recovery occurs when a previously reinforced and recently extinguished response reemerges over the course of time, often at the beginning of a new session of extinction. Spontaneous recovery could underlie instances of treatment relapse that threaten otherwise effective behavioral interventions for problem behavior. In two experiments, we arranged multiple schedules with pigeons and a human child to assess the effects of different training reinforcer rates on spontaneous recovery. In both experiments, responding was both more resistant to extinction and more likely to relapse following training with greater reinforcement rates upon returning to extinction after time off from extinction testing...
January 4, 2018: Journal of the Experimental Analysis of Behavior
https://www.readbyqxmd.com/read/29305890/computer-training-of-attention-and-inhibition-for-youngsters-with-obesity-a-pilot-study
#11
Sandra Verbeken, Caroline Braet, Tiffany Naets, Katrijn Houben, Wouter Boendermaker
Obesity is a widespread problem that starts from an early age. Previous studies suggest that obese youngsters have an attentional bias and an automatic approach tendency towards high-calorie food and display difficulties inhibiting impulses, which may result in a higher intake of (high-calorie) food. An interesting idea for improvement of the current obesity treatment is adding a program that enables to train their difficulties. Subjects were 36 youngsters aged 9-15 years old from an inpatient treatment program for obesity, randomized over a training group and an active control group...
January 3, 2018: Appetite
https://www.readbyqxmd.com/read/29304448/reinstatement-of-instrumental-actions-in-humans-possible-mechanisms-and-their-implications-to-prevent-it
#12
A Matías Gámez, Rodolfo Bernal-Gamboa
The study of post-extinction recovery effects in humans has received significant attention. For instance, research on reinstatement has increased in the last decade. However, most of the studies focus on the return of fear responses. In the present experiments, we used a videogame task to explore the reinstatement of operant behavior in human participants. In Experiment 1, after participants learned to shoot at enemies, they received an extinction procedure that eliminated the shooting behavior. However, the mere reintroduction of the outcome reinstated the original response...
January 2, 2018: Acta Psychologica
https://www.readbyqxmd.com/read/29301026/cerebellar-transcranial-direct-current-stimulation-improves-procedural-learning-in-nonclinical-psychosis-a-double-blind-crossover-study
#13
Tina Gupta, Derek J Dean, Nicholas J Kelley, Jessica A Bernard, Ivanka Ristanovic, Vijay A Mittal
The present double-blind crossover study examines the effects of cerebellar transcranial direct current stimulation (tDCS) in controls and in an analogue population to psychosis: individuals reporting elevated symptoms of nonclinical psychosis (NCP). A total of 18 controls and 24 NCP individuals were randomized into conditions consisting of 25 minutes of anodal (active) or sham cerebellar tDCS. Following this, both groups completed a pursuit rotor task designed to measure procedural learning performance. Participants then returned 1-week later and received the corresponding condition (either active or sham) and repeated the pursuit rotor task...
December 30, 2017: Schizophrenia Bulletin
https://www.readbyqxmd.com/read/29291122/risk-aware-multi-armed-bandit-problem-with-application-to-portfolio-selection
#14
Xiaoguang Huo, Feng Fu
Sequential portfolio selection has attracted increasing interest in the machine learning and quantitative finance communities in recent years. As a mathematical framework for reinforcement learning policies, the stochastic multi-armed bandit problem addresses the primary difficulty in sequential decision-making under uncertainty, namely the exploration versus exploitation dilemma, and therefore provides a natural connection to portfolio selection. In this paper, we incorporate risk awareness into the classic multi-armed bandit setting and introduce an algorithm to construct portfolio...
November 2017: Royal Society Open Science
https://www.readbyqxmd.com/read/29278256/the-purpose-of-united-nations-security-council-practice-contesting-competence-claims-in-the-normative-context-created-by-the-responsibility-to-protect
#15
Jason Ralph, Jess Gifkins
Practice theory provides important insights into the workings of the Security Council. The contribution is currently limited, however, by the conjecture that practice theory operates on 'a different analytical plane' to norm/normative theory. Building on existing critiques, we argue that analysing practices separately from normative positions risks misappropriating competence and reifying practice that is not fit for purpose. This risk is realized in Adler-Nissen and Pouliot's practice-based account of the Libya crisis...
September 2017: Eur J Int Relat
https://www.readbyqxmd.com/read/29273549/older-and-wiser-age-differences-in-foraging-and-learning-by-an-endangered-passerine
#16
Victoria R Franks, Rose Thorogood
Birds use cues when foraging to help relocate food resources, but natural environments provide many potential cues and choosing which to use may depend on previous experience. Young animals have less experience of their environment compared to adults, so may be slower to learn cues or may need to sample the environment more. Whether age influences cue use and learning has, however, received little experimental testing in wild animals. Here we investigate effects of age in a wild population of hihi (Notiomystis cincta), a threatened New Zealand passerine...
December 19, 2017: Behavioural Processes
https://www.readbyqxmd.com/read/29250342/hip-dysplasia-in-wrestlers-three-lessons-learned
#17
J W Thomas Byrd, John C Clohisy, Young-Jo Kim, F Winston Gwathmey, Kay S Jones, Michael B Millis
Hip problems due to dysplasia are commonly associated with female athletes in sports demanding supraphysiologic motion, such as ballet, gymnastics and figure skating. However, hip problems are rarely mentioned among wrestlers, a male sport in which flexibility is advantageous. Dysplasia may have a mostly unrecognized prevalence among wrestlers that can lead to problems and benefit from reorientation periacetabular osteotomy (PAO). Study design in this research is Level 4 evidence case reports. Three consecutive intercollegiate wrestlers ages 20, 21 and 22 years underwent PAO for dysplasia and are reported...
December 2017: Journal of Hip Preservation Surgery
https://www.readbyqxmd.com/read/29240234/prospective-study-feasibility-screening-of-antenatal-total-abnormal-pulmonary-venous-return
#18
Christine Levêque, Louise Paret, Tiffany Cochet, Félicia Joinau-Zoulovits, E Chantalat, F Vidal, Christophe Vayssière, Nadine David
INTRODUCTION: Total Abnormal Pulmonary Venous Return (TAPVR) is a heart defect often missed prenatally, yet at birth it is a surgical emergency. Antenatal detection could be improved by sonographic visualization of the anastomosis of two pulmonary veins in a sinus into the left atrium. The objective of this study is to evaluate the feasibility of this screening method. METHOD: Prospective observational study. Five operators selected one representative image taken during morphological ultrasound screening...
December 14, 2017: Prenatal Diagnosis
https://www.readbyqxmd.com/read/29236354/how-comprehensive-are-research-studies-investigating-the-efficacy-of-technology-enhanced-learning-resources-in-anatomy-education-a-systematic-review
#19
REVIEW
Lauren Clunie, Neil P Morris, Viktoria C T Joynes, James D Pickering
Anatomy education is at the forefront of integrating innovative technologies into its curricula. However, despite this rise in technology numerous authors have commented on the shortfall in efficacy studies to assess the impact such technology-enhanced learning (TEL) resources have on learning. To assess the range of evaluation approaches to TEL across anatomy education, a systematic review was conducted using MEDLINE, the Educational Resources Information Centre (ERIC), Scopus, and Google Scholar, with a total of 3,345 articles retrieved...
December 13, 2017: Anatomical Sciences Education
https://www.readbyqxmd.com/read/29232301/robotic-mitral-valve-repair-the-learning-curve
#20
Avi Goodman, Marijan Koprivanac, Marta Kelava, Stephanie L Mick, A Marc Gillinov, Jeevanantham Rajeswaran, Anna Brzezinski, Eugene H Blackstone, Tomislav Mihaljevic
OBJECTIVE: Adoption of robotic mitral valve surgery has been slow, likely in part because of its perceived technical complexity and a poorly understood learning curve. We sought to correlate changes in technical performance and outcome with surgeon experience in the "learning curve" part of our series. METHODS: From 2006 to 2011, two surgeons undertook robotically assisted mitral valve repair in 458 patients (intent-to-treat); 404 procedures were completed entirely robotically (as-treated)...
November 2017: Innovations: Technology and Techniques in Cardiothoracic and Vascular Surgery
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