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https://www.readbyqxmd.com/read/28436703/in-the-driver-s-seat-development-and-implementation-of-an-e-learning-module-on-return-to-driving-after-stroke
#1
Janet Frith, Isobel Hubbard, Carole James, Helen Warren-Forward
Gaps exist in the knowledge of return-to-driving guidelines, and education is needed for Australian health professionals working in the field of stroke. In this paper, authors evaluate the implementation of an e-learning module. A pre- and post-module knowledge test and survey were used to assess the e-module's success in achieving its learning objectives. Initially, 204 learners completed the module, with 68% of learners scoring 100% in the post-module knowledge test. Only 12 learners completed the survey...
April 24, 2017: Occupational Therapy in Health Care
https://www.readbyqxmd.com/read/28421665/evaluation-of-hifu-ablation-for-uterine-fibroids-an-ideal-prospective-exploration-study
#2
Jinyun Chen, Youping Li, Zhibiao Wang, Peter McCulloch, Liang Hu, Wenzhi Chen, Guanjian Liu, Jing Li, Jinghe Lang
OBJECTIVE: To evaluate the clinical outcomes of High intensity focused ultrasound (HIFU) and surgery in treating uterine fibroids, and prepare for a definitive randomised trial. DESIGN: Prospective multicentre patient choice cohort study (IDEAL Exploratory study) of HIFU, myomectomy or hysterectomy for treating symptomatic uterine fibroids. SETTING: 20 Chinese hospitals. POPULATION OR SAMPLE: 2411 Chinese women with symptomatic fibroids...
April 19, 2017: BJOG: An International Journal of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/28420405/do-international-health-partnerships-contribute-to-reverse-innovation-a-mixed-methods-study-of-thet-supported-partnerships-in-the-uk
#3
Kavian Kulasabanathan, Hamdi Issa, Yasser Bhatti, Matthew Prime, Jacqueline Del Castillo, Ara Darzi, Matthew Harris
BACKGROUND: International health partnerships (IHPs) are changing, with an increased emphasis on mutual accountability and joint agenda setting for both the high- and the low- or middle-income country (LMIC) partners. There is now an important focus on the bi-directionality of learning however for the UK partners, this typically focuses on learning at the individual level, through personal and professional development. We sought to evaluate whether this learning also takes the shape of 'Reverse Innovation' -when an idea conceived in a low-income country is subsequently adopted in a higher-income country...
April 18, 2017: Globalization and Health
https://www.readbyqxmd.com/read/28412960/a-randomised-controlled-trial-to-determine-the-clinical-and-cost-effectiveness-of-thulium-laser-transurethral-vaporesection-of-the-prostate-thuvarp-versus-transurethral-resection-of-the-prostate-turp-in-the-national-health-service-nhs-the-unblocs-trial-a-study
#4
Jo Worthington, Hilary Taylor, Paul Abrams, Sara T Brookes, Nikki Cotterill, Sian M Noble, Tobias Page, K Satchi Swami, J Athene Lane, Hashim Hashim
BACKGROUND: Transurethral resection of the prostate (TURP) has been the standard operation for benign prostatic obstruction (BPO) for 40 years, with approximately 25,000 procedures performed annually, and has remained largely unchanged. It is generally a successful operation, but has well-documented risks for the patient. Thulium laser transurethral vaporesection of the prostate (ThuVARP) vaporises and resects the prostate using a surgical technique similar to TURP. The small amount of study data currently available suggests that ThuVARP may have certain advantages over TURP, including reduced blood loss and shorter hospital stay, earlier return to normal activities, and shorter duration of catheterisation...
April 17, 2017: Trials
https://www.readbyqxmd.com/read/28408411/active-avoidance-neural-mechanisms-and-attenuation-of-pavlovian-conditioned-responding
#5
Emily A Boeke, Justin Moscarello, Joseph E LeDoux, Elizabeth A Phelps, Catherine A Hartley
Patients with anxiety disorders often experience a relapse in symptoms after exposure therapy. Similarly, threat responses acquired during Pavlovian threat conditioning often return after extinction learning. Accordingly, there is a need for alternative methods to persistently reduce threat responding. Studies in rodents have suggested that exercising behavioral control over an aversive stimulus can persistently diminish threat responses, and that these effects are mediated by the amygdala, ventromedial prefrontal cortex (vmPFC), and striatum...
April 13, 2017: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/28404854/autologous-stem-cell-transplantation-disrupts-adaptive-immune-responses-during-rebound-shiv-viremia
#6
Daniel B Reeves, Christopher W Peterson, Hans-Peter Kiem, Joshua T Schiffer
Primary HIV-1 infection induces a virus-specific adaptive/cytolytic immune response that impacts plasma viral load setpoint and rate of progression to AIDS. Combination antiretroviral therapy (cART) suppresses plasma viremia to undetectable levels that rebound upon cART treatment interruption. Following cART withdrawal, the memory component of the virus-specific adaptive immune response may improve viral control compared to primary infection. Here, using primary infection and treatment interruption data from macaques infected with simian/human immunodeficiency virus (SHIV), we observe lower peak viral load but unchanged viral setpoint during viral rebound...
April 12, 2017: Journal of Virology
https://www.readbyqxmd.com/read/28400892/use-of-social-media-by-nurse-educator-students-an-exploratory-survey
#7
Mari Lahti, Heidi Haapaniemi-Kahala, Leena Salminen
BACKGROUND: Information and Communication Technology (ICT) opens up new possibilities for introducing innovative teaching and learning methods to deliver education in different educational areas. Use of internet and social media has grown rapidly and is a key way in how nurses and nurse educator students find information. However, the evidence is still lacking how nurse educator students use social media. OBJECTIVE: The aim of this study is to describe nurse educator students' use of social media and the ways in which their educational needs are related to social media...
2017: Open Nursing Journal
https://www.readbyqxmd.com/read/28397861/preventing-the-return-of-fear-using-reconsolidation-updating-and-methylene-blue-is-differentially-dependent-on-extinction-learning
#8
Allison M Auchter, Jason Shumake, Francisco Gonzalez-Lima, Marie H Monfils
Many factors account for how well individuals extinguish conditioned fears, such as genetic variability, learning capacity and conditions under which extinction training is administered. We predicted that memory-based interventions would be more effective to reduce the reinstatement of fear in subjects genetically predisposed to display more extinction learning. We tested this hypothesis in rats genetically selected for differences in fear extinction using two strategies: (1) attenuation of fear memory using post-retrieval extinction training, and (2) pharmacological enhancement of the extinction memory after extinction training by low-dose USP methylene blue (MB)...
April 11, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28388250/exploring-factors-related-to-the-translation-of-collaborative-research-learning-experiences-into-clinical-practice-opportunities-and-tensions
#9
Simon Fletcher, Cheryl Whiting, Annette Boaz, Scott Reeves
Providing training opportunities to develop research skills for clinical staff has been prioritised in response to the need for improving the evidence base underpinning the delivery of care. By exploring the experiences of a number of former participants of a multidisciplinary postgraduate research course, this article explores the factors that have enabled and impeded staff to translate their learnt research skills into clinical practice. Adopting an exploratory case study approach, 16 interviews with 5 cohorts of Masters by Research in Clinical Practice (MResCP) graduates were undertaken...
April 7, 2017: Journal of Interprofessional Care
https://www.readbyqxmd.com/read/28386228/dynamic-expression-changes-in-the-transcriptome-of-the-prefrontal-cortex-after-repeated-exposure-to-cocaine-in-mice
#10
Mingzhen Li, Peng Xu, Yanhua Xu, Huajing Teng, Weiping Tian, Quansheng Du, Mei Zhao
Prefrontal cortex (PFC)-dependent functions, such as executive function, explicit learning, and memory, are negatively affected in cocaine abusers and experimental animal models of cocaine treatment. However, its molecular mechanisms are less understood. In the present study, we performed transcriptome profiling of the dynamic changes in the PFC after repeated cocaine administration in mice. We found 463, 14, and 535 differentially expressed genes (DEGs) at 2 h, 24 h, and 7 days, respectively, after the withdrawal of chronic cocaine treatment...
2017: Frontiers in Pharmacology
https://www.readbyqxmd.com/read/28383468/united-kingdom-military-surgical-preparedness-for-contingency-operations
#11
Mansoor Khan, Christopher Streets, Nigel Tai, Rory Rickard
The return to contingency operations has led to a new challenge in maintaining the military surgical skillset acquired over a period of nearly two decades of enduring conflict. The United Kingdom's Defence Medical Services have anticipated this change and developed a strategy that incorporates intelligent appointment or re-appointment of surgeons within NHS Major Trauma Centres, as well as ongoing training to ensure lessons are learned and skill fade is mitigated between wars.
April 5, 2017: Journal of Trauma and Acute Care Surgery
https://www.readbyqxmd.com/read/28373651/fatigue-modulates-dopamine-availability-and-promotes-flexible-choice-reversals-during-decision-making
#12
Pierpaolo Iodice, Claudio Ferrante, Luigi Brunetti, Simona Cabib, Feliciano Protasi, Mark E Walton, Giovanni Pezzulo
During decisions, animals balance goal achievement and effort management. Despite physical exercise and fatigue significantly affecting the levels of effort that an animal exerts to obtain a reward, their role in effort-based choice and the underlying neurochemistry are incompletely known. In particular, it is unclear whether fatigue influences decision (cost-benefit) strategies flexibly or only post-decision action execution and learning. To answer this question, we trained mice on a T-maze task in which they chose between a high-cost, high-reward arm (HR), which included a barrier, and a low-cost, low-reward arm (LR), with no barrier...
April 3, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28368789/design-and-implementation-of-a-physician-coaching-pilot-to-promote-value-based-referrals-to-specialty-care
#13
Leah Tuzzio, Evette J Ludman, Eva Chang, Lorella Palazzo, Travis Abbott, Edward H Wagner, Robert J Reid
INTRODUCTION: Referral rates to specialty care from primary care physicians vary widely. To address this variability, we developed and pilot tested a peer-to-peer coaching program for primary care physicians. OBJECTIVES: To assess the feasibility and acceptability of the coaching program, which gave physicians access to their individual-level referral data, strategies, and a forum to discuss referral decisions. METHODS: The team designed the program using physician input and a synthesis of the literature on the determinants of referral...
2017: Permanente Journal
https://www.readbyqxmd.com/read/28368082/-comparison-of-the-wechsler-memory-scale-iii-and-the-spain-complutense-verbal-learning-test-in-acquired-brain-injury-construct-validity-and-ecological-validity
#14
P Luna-Lario, J Pena, N Ojeda
AIMS: To perform an in-depth examination of the construct validity and the ecological validity of the Wechsler Memory Scale-III (WMS-III) and the Spain-Complutense Verbal Learning Test (TAVEC). PATIENTS AND METHODS: The sample consists of 106 adults with acquired brain injury who were treated in the Area of Neuropsychology and Neuropsychiatry of the Complejo Hospitalario de Navarra and displayed memory deficit as the main sequela, measured by means of specific memory tests...
April 16, 2017: Revista de Neurologia
https://www.readbyqxmd.com/read/28366864/dopamine-dependent-setting-of-a-circadian-oscillator-underlying-the-memory-for-time-of-day
#15
Sean W Cain, Omar A Rawashdeh, Michael Siu, Seung Cheol Kim, Martin R Ralph
Animals learn and remember the time of day that significant conditions occur, and anticipate recurrence at 24-h intervals, even after only one exposure to the condition. On several place-conditioning tasks, animals show context avoidance or preference only near the time of day of the experience. The memory for time of day is registered by a circadian oscillator that is set at the time of the training. We show that manipulations of dopamine (DA) neurotransmission can set a time memory in place preference and avoidance tasks, indicating that time of day is part of the context that is learned...
March 30, 2017: Neurobiology of Learning and Memory
https://www.readbyqxmd.com/read/28364938/experiential-and-authentic-learning-approaches-in-vaccine-management
#16
Umit Kartoglu, James Vesper, Hanna Teräs, Thomas Reeves
A high level of concern is placed on the storage, handling, transportation, and distribution of vaccines and other pharmaceutical products, particularly those that are time and temperature sensitive. While active and passive cooling equipment and monitoring devices are important, it is the various personnel responsible for executing and writing procedures, designing and operating systems, and investigating problems and helping prevent them who are paramount in establishing and maintaining a "cold chain" for time and temperature sensitive pharmaceutical products (TTSPPs)...
April 19, 2017: Vaccine
https://www.readbyqxmd.com/read/28359724/tutor-led-teaching-of-procedural-skills-in-the-skills-lab-complexity-relevance-and-teaching-competence-from-the-medical-teacher-tutor-and-student-perspective
#17
Jan Lauter, Sylvie Branchereau, Wolfgang Herzog, Till Johannes Bugaj, Christoph Nikendei
BACKGROUND: In current medical curricula, the transfer of procedural skills has received increasing attention. Skills lab learning and tutor-led teaching have become an inherent part of all medical curricula at German medical faculties. In 2011, the initial basis for the classification of clinical skills in medical school was created by the German Association for Medical Education (GMA) Committee's consensus statement on procedural skills. As a recommendation for medical curricula, the National Competency-based Catalogue of Learning Objectives (NKLM, 2015) lists procedural skills according to their curriculum integration and competency level...
March 28, 2017: Zeitschrift Für Evidenz, Fortbildung und Qualität Im Gesundheitswesen
https://www.readbyqxmd.com/read/28358527/-going-out-of-the-box-close-intercultural-friendships-and-romantic-relationships-spark-creativity-workplace-innovation-and-entrepreneurship
#18
Jackson G Lu, Andrew C Hafenbrack, Paul W Eastwick, Dan J Wang, William W Maddux, Adam D Galinsky
The present research investigates whether close intercultural relationships promote creativity, workplace innovation, and entrepreneurship-outcomes vital to individual and organizational success. We triangulate on these questions with multiple methods (longitudinal, experimental, and field studies), diverse population samples (MBA students, employees, and professional repatriates), and both laboratory and real-world measures. Using a longitudinal design over a 10-month MBA program, Study 1 found that intercultural dating predicted improved creative performance on both divergent and convergent thinking tasks...
March 30, 2017: Journal of Applied Psychology
https://www.readbyqxmd.com/read/28357777/public-s-views-toward-return-of-secondary-results-in-genomic-sequencing-it-s-almost-all-about-the-choice
#19
Kerry A Ryan, Raymond G De Vries, Wendy R Uhlmann, J Scott Roberts, Michele C Gornick
The therapeutic use of genomic sequencing creates novel and unresolved questions about cost, clinical efficacy, access, and the disclosure of sequencing results. The disclosure of the secondary results of sequencing poses a particularly challenging ethical problem. Experts disagree about which results should be shared and public input - especially important for the creation of disclosure policies - is complicated by the complex nature of genetics. Recognizing the value of deliberative democratic methods for soliciting informed public opinion on matters like these, we recruited participants from a clinical research site for an all-day deliberative democracy (DD) session...
March 29, 2017: Journal of Genetic Counseling
https://www.readbyqxmd.com/read/28349615/development-and-perceived-effects-of-an-educational-programme-on-quality-and-safety-in-medication-handling-in-residential-facilities
#20
Anna Mygind, Mira El-Souri, Charlotte Rossing, Linda Aagaard Thomsen
OBJECTIVES: To develop and test an educational programme on quality and safety in medication handling for staff in residential facilities for the disabled. METHODS: The continuing pharmacy education instructional design model was used to develop the programme with 22 learning objectives on disease and medicines, quality and safety, communication and coordination. The programme was a flexible, modular seven + two days' course addressing quality and safety in medication handling, disease and medicines, and medication supervision and reconciliation...
March 27, 2017: International Journal of Pharmacy Practice
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