keyword
MENU ▼
Read by QxMD icon Read
search

Muscle stimulation

keyword
https://www.readbyqxmd.com/read/28545285/-effects-of-apigenin-on-lipopolysaccharide-induced-proliferation-of-rat-aortic-vascular-smooth-muscle-cells
#1
H M Yao, Y P Jia, Z Xue, M Guo, J Y Lyu
Objective: To investigate the effect of natural active compounds apigenin (API) on the proliferation of rat aortic vascular smooth muscle cells (VSMCs) induced by lipopolysaccharide (LPS) and related mechanisms. Methods: VSMCs of primary cultured SD rats were obtained and the cytotoxic effects of API (0, 10, 20, 40 and 80 μmol/L) was explored by CCK-8 method. Impact of LPS (0, 0.1, 1, 10 and 100 μg/ml) on VSMCs proliferation and the impact of API (0, 10, 20, 40 μmol/L) on LPS (10 μmol)-induced VSMCs proliferation by CCK-8 methods...
April 24, 2017: Zhonghua Xin Xue Guan Bing za Zhi
https://www.readbyqxmd.com/read/28544784/presynaptic-congenital-myasthenic-syndrome-with-a-homozygous-sequence-variant-in-lama5-combines-myopia-facial-tics-and-failure-of-neuromuscular-transmission
#2
Ricardo A Maselli, Juan Arredondo, Jessica Vázquez, Jessica X Chong, Michael J Bamshad, Deborah A Nickerson, Marian Lara, Fiona Ng, Victoria L Lo, Peter Pytel, Craig M McDonald
Defects in genes encoding the isoforms of the laminin alpha subunit have been linked to various phenotypic manifestations, including brain malformations, muscular dystrophy, ocular defects, cardiomyopathy, and skin abnormalities. We report here a severe defect of neuromuscular transmission in a consanguineous patient with a homozygous variant in the laminin alpha-5 subunit gene (LAMA5). The variant c.8046C>T (p.Arg2659Trp) is rare and has a predicted deleterious effect. The affected individual, who also carries a rare homozygous sequence variant in LAMA1, had muscle weakness, myopia, and facial tics...
May 25, 2017: American Journal of Medical Genetics. Part A
https://www.readbyqxmd.com/read/28544772/ganglioside-gm3-content-in-skeletal-muscles-is-increased-in-type-2-but-decreased-in-type-1-diabetes-rat-models-implications-of-glycosphingolipid-metabolism-in-pathophysiology-of-diabetes
#3
Josko Bozic, Anita Markotic, Vedrana Cikes-Culic, Anela Novak, Josip Andelo Borovac, Hrvoje Vucemilovic, Gorana Trgo, Tina Ticinovic Kurir
BACKGROUND: Ganglioside GM3 is an abundant constituent of the plasma membrane where its accumulation attenuates insulin receptor signaling. Considering the role of skeletal muscles for insulin-stimulated glucose uptake, the aim of this study was to determine the expression of GM3 and its precursors in skeletal muscle of diabetes mellitus type 1 (DM1) and type 2 (DM2) rat models. METHODS: Diabetes was induced by streptozotocin (55 mg/kg for DM1 and 35 mg/kg for DM2) injection to male Sprague-Dawley rats which were fed with normal pellet diet (DM1 type) or high-fat diet (DM2 type)...
May 22, 2017: Journal of Diabetes
https://www.readbyqxmd.com/read/28543684/multiparity-modifies-contractile-properties-of-pelvic-muscles-affecting-the-genesis-of-vaginal-pressure-in-rabbits
#4
Rhode López-Juárez, René Zempoalteca, Dora Luz Corona-Quintanilla, Ismael Jiménez-Estrada, Francisco Castelán, Margarita Martínez-Gómez
AIMS: To characterize the contractile properties of the bulbospongiosus (Bsm), isquiocavernosus (Ism), and pubococcygeus muscles (Pcm), and their involvement in the genesis of vaginal pressure in nulliparous and multiparous rabbits. METHODS: Age-matched nulliparous and multiparous rabbits were used to record the isometric contractile responses of each muscle as well as the intravaginal pressure evoked by single square electrical pulses and stimulation trains of ascending frequency...
May 24, 2017: Neurourology and Urodynamics
https://www.readbyqxmd.com/read/28542133/protein-disulfide-isomerase-mediated-apoptosis-and-proliferation-of-vascular-smooth-muscle-cells-induced-by-mechanical-stress-and-advanced-glycosylation-end-products-result-in-diabetic-mouse-vein-graft-atherosclerosis
#5
Suning Ping, Shuying Liu, Yuhuan Zhou, Ziqing Li, Yuhuang Li, Kefeng Liu, Adham Sa Bardeesi, Linli Wang, Jingbo Chen, Lie Deng, Jingjing Wang, Hong Wang, Dadi Chen, Zhengyu Zhang, Puyi Sheng, Chaohong Li
Protein disulfide isomerase (PDI) involves cell survival and death. Whether PDI mediates mechanical stretch stress (SS) and/or advanced glycosylation end products (AGEs) -triggered simultaneous increases in proliferation and apoptosis of vascular smooth muscle cells (VSMCs) is unknown. Here, we hypothesized that different expression levels of PDI trigger completely opposite cell fates among the different VSMC subtypes. Mouse veins were grafted into carotid arteries of non-diabetic and diabetic mice for 8 weeks; the grafted veins underwent simultaneous increases in proliferation and apoptosis, which triggered vein graft arterializations in non-diabetic or atherosclerosis in diabetic mice...
May 25, 2017: Cell Death & Disease
https://www.readbyqxmd.com/read/28541423/grip-strength-and-inflammatory-biomarker-profiles-in-very-old-adults
#6
Antoneta Granic, Karen Davies, Carmen Martin-Ruiz, Carol Jagger, Thomas B L Kirkwood, Thomas von Zglinicki, Avan Aihie Sayer
Background: weak grip strength (GS) and chronic inflammation have been implicated in the aetiology of sarcopenia in older adults. Given the interrelationships between inflammatory biomarkers, a summary variable may provide better insight into the relationship between inflammation and muscle strength. This approach has not been investigated in very old adults (aged ≥85) who are at highest risk of muscle weakness. Methods: we used mixed models to explore the prospective association between GS over 5 years in 845 participants in the Newcastle 85+ Study, and inflammatory components identified by principal component analysis (PCA)...
May 25, 2017: Age and Ageing
https://www.readbyqxmd.com/read/28539911/the-use-of-functional-electrical-stimulation-on-the-upper-limb-and-interscapular-muscles-of-patients-with-stroke-for-the-improvement-of-reaching-movements-a-feasibility-study
#7
Alicia Cuesta-Gómez, Francisco Molina-Rueda, Maria Carratala-Tejada, Eukene Imatz-Ojanguren, Diego Torricelli, Juan Carlos Miangolarra-Page
INTRODUCTION: Reaching movements in stroke patients are characterized by decreased amplitudes at the shoulder and elbow joints and greater displacements of the trunk, compared to healthy subjects. The importance of an appropriate and specific contraction of the interscapular and upper limb (UL) muscles is crucial to achieving proper reaching movements. Functional electrical stimulation (FES) is used to activate the paretic muscles using short-duration electrical pulses. OBJECTIVE: To evaluate whether the application of FES in the UL and interscapular muscles of stroke patients with motor impairments of the UL modifies patients' reaching patterns, measured using instrumental movement analysis systems...
2017: Frontiers in Neurology
https://www.readbyqxmd.com/read/28539391/reevaluation-of-reflex-responses-of-the-human-masseter-muscle-to-electrical-lip-stimulation
#8
Paulius Uginčius, Gizem Yilmaz, Oguz Sebik, Kemal Sitki Turker
We examined the reflex response of the human masseter muscle to electrical stimulation of the lip using both single motor unit and surface electromyogram based methods. Using the classical analysis methods, reflex response to mild electrical stimuli generated two distinct short-lasting inhibitions. This pattern may reflect the development of combinations of short and long latency inhibitory postsynaptic potentials as a result of the mildly painful electrical lip stimulation. However, this pattern appearing in the classical analysis methods may have developed as a consequence of earlier responses and may not be genuine...
May 24, 2017: Journal of Neurophysiology
https://www.readbyqxmd.com/read/28539287/-calculation-of-orbital-fat-volumes-for-determining-treatment-timing-for-thyroid-associated-ophthalmopathy
#9
Wei Jiang, Qiu-Yue Cai, Zhang-Fang Li, Zhi-Yi Chen, Yao-Sheng Luo, Shi-di Hu, Jie Shen
OBJECTIVE: To analyze the relationship between orbital fat volume and the progression and prognosis of thyroid- associated ophthalmopathy (TAO) and determine the optimal treatment timing for TAO. METHODS: The clinical data were collected from 35 patients (70 orbits) with a definite diagnosis of TAO between January, 2016 and December, 2016. The correlation between orbital fat volume and the clinical parameters was evaluated. We also analyzed the correlation of the signal intensity ratio (SIR) of the extraocular muscles with the clinical parameters...
May 20, 2017: Nan Fang Yi Ke da Xue Xue Bao, Journal of Southern Medical University
https://www.readbyqxmd.com/read/28539159/anti-microbial-peptide-sr-0379-stimulates-human-endothelial-progenitor-cell-mediated-repair-of-peripheral-artery-diseases
#10
Tae Wook Lee, Soon Chul Heo, Yang Woo Kwon, Gyu Tae Park, Jung Won Yoon, Seung-Chul Kim, Il Ho Jang, Jae Ho Kim
Ischemia is a major plague of modern life. In the search of peptide drug candidates for curing ischemic disease, we evaluated the effects of an anti-microbial peptide SR-0379 on stem cell-mediated therapy of ischemic diseases. Migration and tube-forming ability of human endothelial progenitor cells (EPCs) were enhanced by SR-0379 treatment in vitro. Intramuscular administration of SR-0379 into murine ischemic hindlimb significantly enhanced blood perfusion and decreased tissue necrosis, and increased the number of blood vessels in ischemic muscle...
May 25, 2017: BMB Reports
https://www.readbyqxmd.com/read/28538831/effects-of-laryngeal-manual-therapy-lmt-and-transcutaneous-electrical-nerve-stimulation-tens-in-vocal-folds-diadochokinesis-of-dysphonic-women-a-randomized-clinical-trial
#11
Larissa Thaís Donalonso Siqueira, Kelly Cristina Alves Silverio, Alcione Ghedini Brasolotto, Rinaldo Roberto de Jesus Guirro, Christiano Giácomo Carneiro, Mara Behlau
Purpose: To verify and compare the effect of transcutaneous electrical nerve stimulation (TENS) and laryngeal manual therapy (LMT) on laryngeal diadochokinesis (DDK) of dysphonic women. Methods: Twenty women with bilateral vocal nodules participated and were equally divided into: LMT Group - LMT application; TENS Group - TENS application; both groups received 12 sessions of treatment, twice a week, with a duration of 20 minutes each, applied by the same therapist...
May 15, 2017: CoDAS
https://www.readbyqxmd.com/read/28538438/differential-regulation-of-the-autophagy-and-proteasome-pathways-in-skeletal-muscles-in-sepsis
#12
Flavia Stana, Marija Vujovic, Dominique Mayaki, Jean-Philippe Leduc-Gaudet, Philippe Leblanc, Laurent Huck, Sabah N A Hussain
OBJECTIVES: Skeletal muscle fiber atrophy develops in response to severe sepsis, but it is unclear as to how the proteolytic pathways that are involved in its development are differentially regulated. We investigated the link between sepsis-induced fiber atrophy and activation of the proteasome and autophagy pathways and whether the degree of activation is more severe and sustained in limb muscles than it is in the diaphragm. DESIGN: Randomized controlled experiment...
May 22, 2017: Critical Care Medicine
https://www.readbyqxmd.com/read/28538308/effect-of-electrical-myostimulation-on-the-function-of-lower-leg-muscles
#13
Viktoras Silinskas, Albinas GrŪnovas, Jurate Stanislovaitiene, Alfonsas Buliuolis, Eugenijus Trinkunas, Jonas Poderys
Silinskas, V, Grūnovas, A, Stanislovaitiene, J, Buliuolis, A, Trinkunas, E, and Poderys, J. Effect of electrical myostimulation on the function of lower leg muscles. J Strength Cond Res 31(6): 1577-1584, 2017-Electrical myostimulation (EMS) method is applied to improve skeletal muscle function. The aim of this study was to evaluate the efficacy of EMS applied to the sole and calf muscles on their strength and on maximal sprint performance. Each of 10 training sessions involved 10 seconds of stimulation and 50 seconds of rest for a total of 10 minutes...
June 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/28537978/intralipid-restoration-of-myocardial-contractions-following-bupivacaine-induced-asystole-concentration-and-time-dependence-in-vitro
#14
Wyun Kon Park, Hyun Soo Kim, Soo Hwan Kim, Ja Rang Jung, Carl Lynch, Nar Hyun Min
BACKGROUND: The concentration- and time-response relationships of lipid emulsion (LE; Intralipid) on the recovery of myocardial contractility following bupivacaine (BPV)-induced asystole are poorly defined. METHODS: After achieving asystole by 500-μM BPV, varied concentrations of LE were applied to determine the recovery of stimulated contractile responses and contractions in the cardiac tissues of guinea pigs at a 1.2-Hz stimulation rate. These experiments were performed with LE in either a recirculating (2%-16%) or washout (nonrecirculating) condition (0...
May 19, 2017: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/28536695/cardiac-protection-of-valsartan-on-juvenile-rats-with-heart-failure-by-inhibiting-activity-of-camkii-via-attenuating-phosphorylation
#15
Yao Wu, Feifei Si, Xiaojuan Ji, Kunfeng Jiang, Sijie Song, Qijian Yi
Background. This study was undertaken to determine relative contributions of phosphorylation and oxidation to the increased activity of calcium/calmodulin-stimulated protein kinase II (CaMKII) in juveniles with cardiac myocyte dysfunction due to increased pressure overload. Methods. Juvenile rats underwent abdominal aortic constriction to induce heart failure. Four weeks after surgery, rats were then randomly divided into two groups: one group given valsartan (HF + Val) and the other group given placebo (HF + PBO)...
2017: BioMed Research International
https://www.readbyqxmd.com/read/28536426/toll-like-receptor-4-mediates-lewis-lung-carcinoma-induced-muscle-wasting-via-coordinate-activation-of-protein-degradation-pathways
#16
Guohua Zhang, Zhelong Liu, Hui Ding, Hongyu Miao, Jose M Garcia, Yi-Ping Li
Cancer-induced cachexia, characterized by muscle wasting, is a lethal metabolic syndrome with undefined etiology. Current consensus is that multiple factors contribute to cancer-induced muscle wasting, and therefore therapy requires combinational strategies. Here, we show that Toll-like receptor 4 (TLR4) mediates cancer-induced muscle wasting by directly activating muscle catabolism as well as stimulating an innate immune response in mice bearing Lewis lung carcinoma (LLC), and targeting TLR4 alone effectively abrogate muscle wasting...
May 23, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28536423/fam3b-mediates-high-glucose-induced-vascular-smooth-muscle-cell-proliferation-and-migration-via-inhibition-of-mir-322-5p
#17
Wenxiang Zhang, Siyu Chen, Zhao Zhang, Chen Wang, Chang Liu
The proliferation and migration of vascular smooth muscle cells (VSMCs) play an essential role during the development of cardiovascular diseases (CVDs). While many factors potentially contribute to the abnormal activation of VSMCs, hyperglycemia is generally believed to be a major causative factor. On the other hand, FAM3B (named PANDER for its secretory form) is a uniquely structured protein strongly expressed within and secreted from the endocrine pancreas. FAM3B is co-secreted with insulin from the β-cell upon glucose stimulation and regulates glucose homeostasis...
May 23, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28536315/-skeletal-muscle-stem-cell
#18
Shinsuke Yuasa
Adult skeletal muscle has its own stem cell population known as satellite cells. After muscle injury, quiescent satellite cells are activated and then proliferate and differentiate into mature skeletal muscle to ensure that muscle function is recovered. In our screen for myocyte differentiation-promoting factors, we noted markedly elevated expression of granulocyte-colony stimulating factor receptor(G-CSFR, encoded by csf3r)in the skeletal muscle developing area. Furthermore, G-CSFR was transiently expressed in regenerating myocytes of adult injured skeletal muscle, and extrinsic G-CSF supported short-term and long-term muscle regeneration in mouse model of skeletal muscle injury...
2017: Clinical Calcium
https://www.readbyqxmd.com/read/28536271/contrasting-modulatory-effects-from-the-dorsal-and-ventral-premotor-cortex-on-primary-motor-cortex-outputs
#19
Sandrine L Côté, Adjia Hamadjida, Stephan Quessy, Numa Dancause
The dorsal and ventral premotor cortices (PMd and PMv) each take part in unique aspects for the planning and execution of hand movements. These premotor areas are components of complex anatomical networks that include the primary motor cortex (M1) of both hemispheres. One way PMd and PMv could play distinct roles for hand movements is by differently modulating the outputs of M1. Yet, patterns of effects from PMd and PMv on the outputs of M1 have not been systematically compared. Our goals were to study how PMd within the same (i...
May 23, 2017: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/28536255/neuroprotective-effect-of-electroacupuncture-and-upregulation-of-hypoxia-inducible-factor-1%C3%AE-during-acute-ischaemic-stroke-in-rats
#20
Ce Li, Tingting Zhang, Kewei Yu, Hongyu Xie, Yulong Bai, Li Zhang, Yi Wu, Nianhong Wang
BACKGROUND: Acupuncture is a traditional method that has been widely used in various fields of medicine with therapeutic effect. However, evidence of effectiveness to support the application of electroacupuncture (EA) during the process of ischaemia is scarce. OBJECTIVES: To investigate dynamic changes in hypoxia-inducible factor (HIF)-1α expression as well as its association with neurological status in rats subjected to acute ischaemic stroke and EA intervention...
May 23, 2017: Acupuncture in Medicine: Journal of the British Medical Acupuncture Society
keyword
keyword
54956
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"