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https://www.readbyqxmd.com/read/29220680/adherence-to-physical-activity-recommendations-and-physical-and-mental-health-risk-in-people-with-severe-mental-illness-in-uganda
#1
Davy Vancampfort, Michel Probst, David Basangwa, Marc De Hert, Inez Myin-Germeys, Ruud van Winkel, Philip B Ward, Simon Rosenbaum, James Mugisha
This study investigated cardio-metabolic risk factors among patients with severe mental illness who do or do not meet the recommendations of 150min per week of physical activity. A secondary aim was to assess whether those that do meet the recommendations report lower levels of mental health symptoms. 107 (60♀) Ugandan in- and outpatients (mean age=34.4 ± 9.7 years) with severe mental illness (depression=7, bipolar disorder=55, schizophrenia=45) completed the Physical Activity Vital Sign (PAVS) method and Brief Symptoms Inventory -18...
November 29, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/29217725/atrial-fibrillation-in-patients-with-severe-mental-disorders-and-the-risk-of-stroke-fatal-thromboembolic-events-and-bleeding-a-nationwide-cohort-study
#2
Mette Søgaard, Flemming Skjøth, Jette Nordstrøm Kjældgaard, Torben Bjerregaard Larsen, Søren Pihlkjær Hjortshøj, Sam Riahi
OBJECTIVES: Outcomes of atrial fibrillation (AF) in patients with severe mental disorders are largely unknown. We compared rates of stroke, fatal thromboembolic events and bleeding in patients with AF with and without mental disorders. DESIGN: Nationwide registry-based cohort study. SETTING: Denmark (population 5.6 million), 2000-2015. PARTICIPANTS: Patients with AF with schizophrenia (n=534), severe depression (n=400) or bipolar disease (n=569) matched 1:5 on age, sex and calendar time to patients with AF without mental disorders...
December 6, 2017: BMJ Open
https://www.readbyqxmd.com/read/29216484/beliefs-about-the-causes-of-and-treatments-for-depression-and-bipolar-disorder-among-south-koreans
#3
Subin Park, Hyesue Jang, Adrian Furnham, Mina Jeon, Se Jin Park
Public beliefs about psychiatric disorders are important for understanding help-seeking behaviours. We investigated factors that affect South Koreans' beliefs about the causes and treatment of depression and bipolar disorder. We recruited 654 participants aged 15-54 years using an online panel survey. Participants completed two questionnaires: 34 possible causes of and 33 possible treatments for depression and bipolar disorder. For both disorders, the questionnaires about causes revealed four factors: social-environmental, God/fate, heath/lifestyle, and biological; the questionnaires about treatments revealed five factors: self-help/stress management, physical treatment/health management, seeking mental health services, religious help, and resting...
November 21, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/29212563/clinically-relevant-and-simple-immune-system-measure-is-related-to-symptom-burden-in-bipolar-disorder
#4
Ole Köhler-Forsberg, Louisa Sylvia, Thilo Deckersbach, Michael Joshua Ostacher, Melvin McInnis, Dan Iosifescu, Charles Bowden, Susan McElroy, Joseph Calabrese, Michael Thase, Richard Charles Shelton, Mauricio Tohen, James Kocsis, Edward Friedman, Terence Ketter, Andrew Alan Nierenberg
OBJECTIVE: Immunological theories, particularly the sickness syndrome theory, may explain psychopathology in mood disorders. However, no clinical trials have investigated the association between overall immune system markers with a wide range of specific symptoms including potential gender differences. METHODS: We included two similar clinical trials, the lithium treatment moderate-dose use study and clinical and health outcomes initiatives in comparative effectiveness for bipolar disorder study, enrolling 765 participants with bipolar disorder...
December 7, 2017: Acta Neuropsychiatrica
https://www.readbyqxmd.com/read/29211117/adaptation-and-validation-of-the-melbourne-decision-making-questionnaire-to-brazilian-portuguese
#5
Charles Cotrena, Laura Damiani Branco, Rochele Paz Fonseca
INTRODUCTION: Decision making (DM) is among the most important abilities for everyday functioning. However, the most widely used measures of DM come from behavioral paradigms, whose ecological validity and standalone use has been criticized in the literature. Though these issues could be addressed by the use of DM questionnaires as a complementary assessment method, no such instruments have been validated for use in Brazilian Portuguese. Therefore, the aim of this study was to conduct the translation and validation of the Melbourne Decision Making Questionnaire (MDMQ) for use in a Brazilian population...
December 4, 2017: Trends in Psychiatry and Psychotherapy
https://www.readbyqxmd.com/read/29209876/mentalization-deficit-in-bipolar-patients-during-an-acute-depressive-and-manic-episode-association-with-cognitive-functions
#6
Anna Bodnar, Janusz K Rybakowski
BACKGROUND: A number of studies in bipolar patients have shown a deficit in mentalization (theory of mind), one of the main aspects of social cognition. The aim of current study was to assess both cognitive and affective mentalization in well-defined groups of depressed and manic bipolar patients, compared to healthy control subjects, using a battery of tests measuring mentalization processes. The second aim was to investigate a possible relationship between cognitive and affective mentalization and cognitive functions in bipolar patients during a depressive and manic episode...
December 6, 2017: International Journal of Bipolar Disorders
https://www.readbyqxmd.com/read/29207008/cannabis-use-and-hypomania-in-young-people-a-prospective-analysis
#7
Steven Marwaha, Catherine Winsper, Paul Bebbington, Daniel Smith
Background: Cannabis use in young people is common and associated with psychiatric disorders. However, the prospective link between cannabis use and bipolar disorder symptoms has rarely been investigated. The study hypothesis was that adolescent cannabis use is associated with hypomania in early adulthood via several potential etiological pathways. Methods: Data were used from the Avon Longitudinal Study of Parents and Children, a UK birth cohort study. The prospective link between cannabis use at age 17 and hypomania at age 22-23 years was tested using regression analysis, adjusted for gender, early environmental risk factors, alcohol and drug use, and depression and psychotic symptoms at age 18 years...
November 28, 2017: Schizophrenia Bulletin
https://www.readbyqxmd.com/read/29202177/distinctive-neuroanatomical-substrates-for-depression-in-bipolar-disorder-versus-major-depressive-disorder
#8
Koji Matsuo, Kenichiro Harada, Yusuke Fujita, Yasumasa Okamoto, Miho Ota, Hisashi Narita, Benson Mwangi, Carlos A Gutierrez, Go Okada, Masahiro Takamura, Hirotaka Yamagata, Ichiro Kusumi, Hiroshi Kunugi, Takeshi Inoue, Jair C Soares, Shigeto Yamawaki, Yoshifumi Watanabe
No neuroanatomical substrates for distinguishing between depression of bipolar disorder (dBD) and major depressive disorder (dMDD) are currently known. The aim of the current multicenter study was to identify neuroanatomical patterns distinct to depressed patients with the two disorders. Further analysis was conducted on an independent sample to enable generalization of results. We directly compared MR images of these subjects using voxel-based morphometry (VBM) and a support vector machine (SVM) algorithm using 1531 participants...
November 30, 2017: Cerebral Cortex
https://www.readbyqxmd.com/read/29200575/are-we-overdiagnosing-bipolar-disorder
#9
M S Reddy, Starlin M Vijay, Swetha Reddy
Bipolar disorder (BD) is an established diagnostic entity used by clinicians for over a century. It is distinguished by the distinct manic and depressive episodes with interepisode euthymia. It has an illness course where both recovery and recurrences are a rule and has a good long-term prognosis, as reported earlier by Emil Kraeplin. There is an opinion in the current literature that BD is often underdiagnosed as unipolar depression, and based on that opinion, spectrum concept was introduced. Here, we present 5 cases to highlight that overdiagnosis of BD is also not infrequent and we discuss its reasons and therapeutic implications...
September 2017: Indian Journal of Psychological Medicine
https://www.readbyqxmd.com/read/29199810/ketamine-as-treatment-for-depression
#10
Tero Taiminen
Ketamine infusions administered intravenously 1 to 3 times per week are the quickest and most effective treatment for depression. Short-course ketamine medication is established treatment both for unipolar depression and depressive episodes of bipolar affective disorder. Ketamine is suitable for initiating the treatment for treatment-resistant depression, alleviation of suicidal tendencies, and treatment of depressive patients suffering from simultaneous pain. The safety of prolonged treatment with ketamine is not known to sufficient degree...
2017: Duodecim; Lääketieteellinen Aikakauskirja
https://www.readbyqxmd.com/read/29199760/effectivity-and-cost-effectivity-of-the-maintenance-electroconvulsive-therapy-a-mirror-naturalistic-analysis
#11
Albert Cosculluela, Jesús Cobo, Erika Martínez-Amorós, Montse Paños, Angel M Santiago, Sara Crivillés, María Camposo, Joan C Oliva, Albert Granero, Diego J Palao
INTRODUCTION: Maintenance Electroconvulsive Therapy (mECT) is a biological long-term treatment in which patients receive ECT on periods from 2 to 4 weeks, during a variable period of time, usually for more than 6 months. Recent studies showed the efficacy of mECT in prevention of relapse and recurrences. Our study wants to demostrate the effectivity and cost-effectivity of this therapy in the naturalistic conditions of our area. METHODOLOGY: HASH(0x3a9d190) DESIGN: Retrospective longitudinal study, with mirror analysis in naturalistic conditions...
November 2017: Actas Españolas de Psiquiatría
https://www.readbyqxmd.com/read/29197196/analysis-of-the-prevalence-of-mental-disorders-in-psoriasis-the-relevance-of-psychiatric-assessment-in-dermatology
#12
Bárbara Roque Ferreira, José Luís Pio-Abreu, José Pedro Reis, Américo Figueiredo
BACKGROUND: The boundary between Dermatology and Psychiatry has increasing recognition. Psoriasis is a common psychophysiological skin disease with a major impact on patient's quality of life and a paradigmatic example of a pathology in that boundary. Studies are needed to exactly point out the prevalence of specific psychopathology and mental disorders associated with psoriasis. This work intends to analyse the prevalence of psychopathology and psychiatric comorbidities in patients with psoriasis...
December 2017: Psychiatria Danubina
https://www.readbyqxmd.com/read/29197116/biological-systems-are-a-common-link-between-alcohol-use-disorder-and-co-occurring-psychiatric-and-medical-conditions
#13
Sarah L Hagerty, Jarrod M Ellingson, Kent E Hutchison
Alcohol use disorder (AUD) commonly co-occurs with other psychiatric and medical conditions. For example, individuals with AUD are nearly four-times more likely to have Major Depressive Disorder (MDD), six-times more likely to have Bipolar Disorder, and twice as likely to be diagnosed with Post Traumatic Stress Disorder (PTSD) (Kessler et al., 2003). Additionally, medical conditions are commonly comorbid with AUD, and heavy, chronic alcohol use is a risk factor for a host of wide-ranging medical disorders (Rehm et al...
December 2, 2017: Alcoholism, Clinical and Experimental Research
https://www.readbyqxmd.com/read/29196072/social-involvement-issues-in-patients-with-becker-muscular-dystrophy-a-questionnaire-survey-of-subjects-from-a-patient-registry
#14
Madoka Mori-Yoshimura, Yukio Mizuno, Sumiko Yoshida, Narihiro Minami, Naohiro Yonemoto, Fumi Takeuchi, Ichizo Nishino, Miho Murata, Shin'ichi Takeda, Yuji Takahashi, En Kimura
BACKGROUND: Little is known about the relationship between Becker Muscular Dystrophy (BMD) and developmental problems, school life, employment, and mental problems. We aimed to clarify whether BMD is a risk factor for developmental disorders, problematic behavior, psychiatric diseases, and other social difficulties in school life and employment. METHODS: Adults with genetically or immunohistochemically confirmed BMD from the Registry of Muscular Dystrophy in Japan (REMUDY) were asked to complete a questionnaire regarding patient history, school life, employment, and mental problems...
November 29, 2017: Brain & Development
https://www.readbyqxmd.com/read/29195773/cognitive-deficits-in-bipolar-disorders-implications-for-emotion
#15
REVIEW
Isabela M M Lima, Andrew D Peckham, Sheri L Johnson
Prominent cognitive deficits have been documented in bipolar disorder, and multiple studies suggest that these deficits can be observed among non-affected first-degree relatives of those with bipolar disorder. Although there is variability in the degree of cognitive deficits, these deficits are robustly relevant for functional outcomes. A separate literature documents clear difficulties in emotionality, emotion regulation, and emotion-relevant impulsivity within bipolar disorder, and demonstrates that these emotion-relevant variables are also central to outcome...
November 21, 2017: Clinical Psychology Review
https://www.readbyqxmd.com/read/29195125/effects-of-continuation-electroconvulsive-therapy-on-quality-of-life-in-elderly-depressed-patients-a-randomized-clinical-trial
#16
W Vaughn McCall, Sarah H Lisanby, Peter B Rosenquist, Mary Dooley, Mustafa M Husain, Rebecca G Knapp, Georgios Petrides, Matthew V Rudorfer, Robert C Young, Shawn M McClintock, Martina Mueller, Joan Prudic, Robert M Greenberg, Richard D Weiner, Samuel H Bailine, Nagy A Youssef, Laryssa McCloud, Charles H Kellner
We examined whether electroconvulsive therapy (ECT) plus medications ("STABLE + PHARM" group) had superior HRQOL compared with medications alone ("PHARM" group) as continuation strategy after successful acute right unilateral ECT for major depressive disorder (MDD). We hypothesized that scores from the Medical Outcomes Study Short Form-36 (SF-36) would be higher during continuation treatment in the "STABLE + PHARM" group versus the "PHARM" group. The overall study design was called "Prolonging Remission in Depressed Elderly" (PRIDE)...
November 16, 2017: Journal of Psychiatric Research
https://www.readbyqxmd.com/read/29192944/-reliability-and-validity-study-of-the-turkish-version-of-hypomania-checklist-32-revised
#17
Simavi Vahip, Ömer Aydemir, Cengiz Akkaya, Kürşat Altınbaş, Kaan Kora, Didem Sücüllüoğlu Dikici, Fatma Akdeniz, Fatma Kalaycı, Timuçin Oral, Işıl Vahip, Müge Alkan, Jules Angst
OBJECTIVE: In this study, it is aimed to evaluate the reliability and validity of the Turkish version of Hypomania Checklist-32-Revised. METHOD: The study was carried out with 80 patients diagnosed with bipolar I disorder, 26 patients diagnosed with bipolar II disorder and 42 patients diagnosed with major depressive disorder attending the out- and in-patient psychiatry departments of three university hospitals and one training hospital, and 116 healthy volunteers consisting of university students...
2017: Türk Psikiyatri Dergisi, Turkish Journal of Psychiatry
https://www.readbyqxmd.com/read/29192581/genetic-influences-on-evening-preference-overlap-with-those-for-bipolar-disorder-in-a-sample-of-mexican-americans-and-american-indians
#18
Whitney E Melroy-Greif, Ian R Gizer, Kirk C Wilhelmsen, Cindy L Ehlers
Diurnal preference (e.g., being an owl or lark) has been associated with several psychiatric disorders including bipolar disorder (BP), major depressive disorder, and substance use disorders. Previous large-scale genome-wide association studies (GWAS) aimed at identifying genetic influences on diurnal preference have exclusively included subjects of European ancestry. This study examined the genetic architecture of diurnal preference in two minority samples: a young adult sample of Mexican Americans (MAs), and a family-based sample of American Indians (AIs)...
December 2017: Twin Research and Human Genetics: the Official Journal of the International Society for Twin Studies
https://www.readbyqxmd.com/read/29191242/copy-number-variation-meta-analysis-reveals-a-novel-duplication-at-9p24-associated-with-multiple-neurodevelopmental-disorders
#19
Joseph T Glessner, Jin Li, Dai Wang, Michael March, Leandro Lima, Akshatha Desai, Dexter Hadley, Charlly Kao, Raquel E Gur, Nadine Cohen, Patrick M A Sleiman, Qingqin Li, Hakon Hakonarson
BACKGROUND: Neurodevelopmental and neuropsychiatric disorders represent a wide spectrum of heterogeneous yet inter-related disease conditions. The overlapping clinical presentations of these diseases suggest a shared genetic etiology. We aim to identify shared structural variants spanning the spectrum of five neuropsychiatric disorders. METHODS: We investigated copy number variations (CNVs) in five cohorts, including schizophrenia (SCZ), bipolar disease (BD), autism spectrum disorders (ASD), attention deficit hyperactivity disorder (ADHD), and depression, from 7849 cases and 10,799 controls...
November 30, 2017: Genome Medicine
https://www.readbyqxmd.com/read/29187746/genome-wide-haplotype-based-association-analysis-of-major-depressive-disorder-in-generation-scotland-and-uk-biobank
#20
David M Howard, Lynsey S Hall, Jonathan D Hafferty, Yanni Zeng, Mark J Adams, Toni-Kim Clarke, David J Porteous, Reka Nagy, Caroline Hayward, Blair H Smith, Alison D Murray, Niamh M Ryan, Kathryn L Evans, Chris S Haley, Ian J Deary, Pippa A Thomson, Andrew M McIntosh
Genome-wide association studies using genotype data have had limited success in the identification of variants associated with major depressive disorder (MDD). Haplotype data provide an alternative method for detecting associations between variants in weak linkage disequilibrium with genotyped variants and a given trait of interest. A genome-wide haplotype association study for MDD was undertaken utilising a family-based population cohort, Generation Scotland: Scottish Family Health Study (n = 18,773), as a discovery cohort with UK Biobank used as a population-based replication cohort (n = 25,035)...
November 30, 2017: Translational Psychiatry
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