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https://www.readbyqxmd.com/read/29765604/deciphering-mineralogical-changes-and-carbonation-development-during-hydration-and-ageing-of-a-consolidated-ternary-blended-cement-paste
#1
Francis Claret, Sylvain Grangeon, Annick Loschetter, Christophe Tournassat, Wout De Nolf, Nicholas Harker, Faiza Boulahya, Stéphane Gaboreau, Yannick Linard, Xavier Bourbon, Alejandro Fernandez-Martinez, Jonathan Wright
To understand the main properties of cement, a ubiquitous material, a sound description of its chemistry and mineralogy, including its reactivity in aggressive environments and its mechanical properties, is vital. In particular, the porosity distribution and associated sample carbonation, both of which affect cement's properties and durability, should be quantified accurately, and their kinetics and mechanisms of formation known both in detail and in situ . However, traditional methods of cement mineralogy analysis ( e...
March 1, 2018: IUCrJ
https://www.readbyqxmd.com/read/29761487/the-phytoestrogen-genistein-prevents-trabecular-bone-loss-and-affects-thyroid-follicular-cells-in-a-male-rat-model-of-osteoporosis
#2
Branko Filipović, Branka Šošić-Jurjević, Vladimir Ajdžanović, Jasmina Živanović, Milica Manojlović-Stojanoski, Nataša Nestorović, Nataša Ristić, Svetlana Trifunović, Verica Milošević
As a major phytoestrogen of soy, genistein effectively prevents bone loss in both humans and rat models of osteoporosis. However, although the bone-sparing effects of genistein are achieved directly through estrogen receptors, its mode of action on bone by modulation of other endocrine functions is not entirely clear. Thus, thyroid hormones and calcitonin (CT) have an essential influence on bone metabolism. Besides its action on bones, in this study we examined the effect of genistein on the activity of two different endocrine cell populations, thyroid follicular and C-cells...
May 14, 2018: Journal of Anatomy
https://www.readbyqxmd.com/read/29757564/-re-operation-treatment-in-uremic-patients-complicated-with-persistent-secondary-hyperparathyroidism-after-parathyroidectomy-with-autotransplantation
#3
Shao Jun Bo, Xian Fa Xu, Chuan Ya Qiu, Tian Tian Wang, Yu Dong Ning, Hong Yue Li
Objective: To analyze the clinical profile and therapeutic effect of re-operation treatment in uremic patients complicated with persistent secondary hyperparathyroidism(SHPT)after parathyroidectomy with autotransplantation. Method: Twelve persistent SHPT patients who were treated with reoperation of paramyroidectomy(PTX)were enrolled in this study during the period from Jan 2014 to Jul 2017 in our hospital.We evaluated the location of the remaining parathyroid glands by ultrasonography,dual-phase 99 Tcm-sestamibi scintigraphy,CT and MR imaging of the neck before the operation...
January 20, 2018: Journal of Clinical Otorhinolaryngology, Head, and Neck Surgery
https://www.readbyqxmd.com/read/29755405/dual-paraneoplastic-endocrine-syndromes-heralding-onset-of-extrapulmonary-small-cell-carcinoma-a-case-report-and-narrative-review
#4
Jill B Feffer, Natalia M Branis, Jeanine B Albu
Objective: Extrapulmonary small cell carcinoma (EPSCC) is rare and frequent metastases at presentation can complicate efforts to identify a site of origin. In particular, SCC comprises <1% of prostate cancers and has been implicated in castration resistance. Methods: Clinical, laboratory, imaging, and pathology data are presented. Results: A 56-year-old man with locally advanced prostate adenocarcinoma on androgen deprivation therapy presented with a clogged nephrostomy tube...
2018: Frontiers in Endocrinology
https://www.readbyqxmd.com/read/29752156/spectral-ct-imaging-of-lung-cancer-quantitative-analysis-of-spectral-parameters-and-their-correlation-with-tumor-characteristics
#5
Feng Wu, Hang Zhou, Feng Li, Jiang-Tao Wang, Tao Ai
RATIONALE AND OBJECTIVES: Spectral computed tomography (CT) imaging is widely used in the diagnosis of various cancers. This study aimed to analyze the characteristics of lung squamous cell carcinoma (SC) and adenocarcinoma (AC) using spectral CT imaging. METHODS: Sixty patients who were examined via spectral CT imaging and confirmed as having AC or SC via surgery and pathology were enrolled in this research project. A spectrum CT scanner was used, and both plain and enhanced CT scans were conducted to acquire spectral images...
May 8, 2018: Academic Radiology
https://www.readbyqxmd.com/read/29750809/histological-validation-of-calcifications-in-the-human-hippocampus-as-seen-on-computed-tomography
#6
Melissa E M Peters, Remko Kockelkoren, Esther J M de Brouwer, Huiberdina L Koek, Ronald L A W Bleys, Willem P Th M Mali, Jeroen Hendrikse, Annemieke M Rozemuller, Pim A de Jong
BACKGROUND: Calcifications within the hippocampus were recently described for the first time on computed tomography (CT). These calcifications appeared in patients older than 50 years, the prevalence increases with age and they may be associated with cognitive decline. The aim of this study was to determine the histological basis (the presence, severity and location) of these CT-detected hippocampal calcifications of post-mortem brains. METHODS: CT scans of seven post-mortem brains were scored for the presence and severity (mild, moderate, severe) of hippocampal calcification...
2018: PloS One
https://www.readbyqxmd.com/read/29747780/comparison-of-miniaturized-percutaneous-nephrolithotomy-and-flexible-ureterorenoscopy-for-moderate-size-renal-stones-in-elderly-patients
#7
Faruk Ozgor, Fatih Yanaral, Metin Savun, Harun Ozdemir, Ufuk Caglar, Omer Sarilar
Life expectancy has become longer, thus the number of elderly people who require treatment for nephrolithiasis has increased. We aimed to analyze the efficacy of flexible ureterorenoscopy (f-URS) and miniaturized percutaneous nephrolithotomy (mPNL) in the management of 10 and 30 mm renal stones in patients aged >60 years. In prospective non-randomized series, the data of patients who underwent f-URS or mPNL for kidney stones between July 2013 and July 2016 were analyzed. The procedure was accepted as successful if the patient was achieved complete stone clearance according to CT imaging between 1-3 months postoperatively...
June 2018: Kaohsiung Journal of Medical Sciences
https://www.readbyqxmd.com/read/29745818/novel-insights-into-renal-mineralization-and-stone-formation-through-advanced-imaging-modalities
#8
Scott V Wiener, Ling Chen, Alex R Shimotake, Misun Kang, Marshall L Stoller, Sunita P Ho
Purpose/Aim: The most common kidney stone composed of calcium oxalate forms on interstitial calcium phosphate mineral known as a Randall's plaque (RP). Due to limited information about events leading to the initial deposition of nanometer size interstitial calcium phosphate pre-clusters, there continues to be a debate on the initial site of calcium phosphate deposition and factors leading to stone formation. MATERIALS AND METHODS: High-resolution X-ray micro-computed tomography (CT), and light and electron microscopy techniques were used to characterize human renal pyramids and five representative kidney stones with identifiable stems...
December 2018: Connective Tissue Research
https://www.readbyqxmd.com/read/29735255/computed-tomography-predictors-of-mortality-stroke-and-conduction-disturbances-in-women-undergoing-tavr-a-sub-analysis-of-the-win-tavi-registry
#9
Marco Spaziano, Alaide Chieffo, Yusuke Watanabe, Jaya Chandrasekhar, Samantha Sartori, Thierry Lefèvre, Anna Sonia Petronio, Patrizia Presbitero, Didier Tchetche, Alessandro Iadanza, Nicholas M Van Mieghem, Julinda Mehilli, Roxana Mehran, Marie-Claude Morice
BACKGROUND: Aortic valve calcification patterns were associated with short- and long-term outcomes in previous small observational datasets of patients undergoing transcatheter aortic valve implantation (TAVI). The specific impact of multi detector-row computed tomography (MDCT) findings on outcomes in women has not been reported. We sought to describe the associations between MDCT characteristics and clinical outcomes in a registry of 547 women undergoing TAVI. METHODS: WIN-TAVI is the first all-female registry to study the safety and effectiveness of TAVI in women (n = 1019)...
April 27, 2018: Journal of Cardiovascular Computed Tomography
https://www.readbyqxmd.com/read/29735138/transpedicular-decompression-debridement-and-posterior-spinal-fusion-with-instrumentation-for-single-level-thoracic-spinal-tuberculosis-with-myelopathy-is-anterior-column-reconstruction-necessary
#10
Saumyajit Basu, Sri Krishna Chaitanya Kondety
OBJECTIVES: The purpose of this study is to study the safety and efficacy of single-stage transpedicular decompression/debridement and instrumented posterior spinal fusion for single-level thoracic spinal tuberculosis with myelopathy without anterior column reconstruction. SUMMARY OF BACKGROUND DATA: Existing literature has many reports of transpedicular decompression/debridement and instrumented posterior spinal fusion with anterior column reconstruction. The quoted loss of correction is around 2°, but there is no strong evidence analyzing the loss of kyphosis correction, assessment of fusion in the same, without anterior column reconstruction...
May 2018: Spine Deformity
https://www.readbyqxmd.com/read/29734858/current-and-future-applications-of-ct-coronary-calcium-assessment
#11
Christian Tesche, Taylor M Duguay, U Joseph Schoepf, Marly van Assen, Carlo N De Cecco, Moritz H Albrecht, Akos Varga-Szemes, Richard R Bayer, Ullrich Ebersberger, John W Nance, Christian Thilo
Computed tomographic (CT) coronary artery calcium scoring (CAC) has been validated as a well-established screening method for cardiovascular risk stratification and treatment management that is used in addition to traditional risk factors. The purpose of this review is to present an update on current and future applications of CAC. Areas covered: The topic of CAC is summarized from its introduction to current application with focus on the validation and clinical integration including cardiovascular risk prediction and outcome, cost-effectiveness, impact on downstream medical testing, and the technical advances in scanner and software technology that are shaping the future of CAC...
May 8, 2018: Expert Review of Cardiovascular Therapy
https://www.readbyqxmd.com/read/29729524/dysregulation-of-nrxn1-by-mutant-mir8485-leads-to-calcium-overload-in-pre-synapses-inducing-neurodegeneration-in-multiple-sclerosis
#12
Yogita Kattimani, Avinash M Veerappa
OBJECTIVES: To identify Damaging mutations in microRNAs (miRNAs) and 3' untranslated regions (UTRs) of target genes to establish Multiple sclerosis (MS) disease pathway. METHODS: Female aged 16, with Relapsing Remitting Multiple sclerosis (RRMS) was reported with initial symptoms of blurred vision, severe immobility, upper and lower limb numbness and backache. Whole Exome Sequencing (WES) and disease pathway analysis was performed to identify mutations in miRNAs and UTRs...
April 9, 2018: Multiple Sclerosis and related Disorders
https://www.readbyqxmd.com/read/29725715/fermented-dairy-products-consumption-is-associated-with-attenuated-cortical-bone-loss-independently-of-total-calcium-protein-and-energy-intakes-in-healthy-postmenopausal-women
#13
E Biver, C Durosier-Izart, F Merminod, T Chevalley, B van Rietbergen, S L Ferrari, R Rizzoli
A longitudinal analysis of bone microstructure in postmenopausal women of the Geneva Retirees Cohort indicates that age-related cortical bone loss is attenuated at non-bearing bone sites in fermented dairy products consumers, not in milk or ripened cheese consumers, independently of total energy, calcium, or protein intakes. INTRODUCTION: Fermented dairy products (FDP), including yogurts, provide calcium, phosphorus, and proteins together with prebiotics and probiotics, all being potentially beneficial for bone...
May 3, 2018: Osteoporosis International
https://www.readbyqxmd.com/read/29721809/gushukang-exerts-osteopreserve-effects-by-regulating-vitamin-d-and-calcium-metabolism-in-ovariectomized-mice
#14
Xiao-Li Li, Liang Wang, Xiao-Lei Bi, Bing-Bing Chen, Yan Zhang
Calcium homeostasis plays vital roles in the management of bone health. Traditional herbal formula Gushukang (GSK) was clinically applied to treat primary osteoporosis. This study aimed to explore the osteoprotective effects of GSK and its roles in maintaining calcium homeostasis in ovariectomized (OVX) mice. The OVX mice were orally treated with low (0.38 g/kg), middle (0.76 g/kg) and high (1.52 g/kg) dose of GSK for 8 weeks. GSK treatment dramatically increased serum calcium level and decreased urinary calcium excretion as well as enhanced calcium content in bone of OVX mice...
May 2, 2018: Journal of Bone and Mineral Metabolism
https://www.readbyqxmd.com/read/29713180/calcification-score-versus-arterial-stenosis-grading-comparison-of-two-ct-based-methods-for-risk-assessment-of-anastomotic-leakage-after-esophagectomy-and-gastric-pull-up
#15
De-Hua Chang, Sebastian Brinkmann, Lucy Smith, Ingrid Becker, Wolfgang Schroeder, Arnulf H Hoelscher, Stefan Haneder, David Maintz, Judith Eva Spiro
Purpose: Anastomotic leakage is a major surgical complication following esophagectomy and gastric pull-up. Specific risk factors such as celiac trunk (TC) stenosis and high calcification score of the aorta have been identified, but no data are available on their relative prognostic values. This retrospective study aimed to compare and evaluate calcification score versus stenosis quantification with regards to prognostic impact on anastomotic leakage. Patients and methods: Preoperative contrast-enhanced computed tomography scans of 164 consecutive patients with primary esophageal cancer were evaluated by two radiologists to apply a calcification score (0-3 scale) assessing the aorta, the celiac axis and the right and left postceliac arteries...
2018: Therapeutics and Clinical Risk Management
https://www.readbyqxmd.com/read/29705974/extreme-hypercalcemia-in-a-kidney-transplant-recipient
#16
Erol Demir, Cagla Karaoglan, Gulcin Yegen, Betul Sair, Halil Yazici, Aydin Turkmen, Mehmet Sukru Sever
Post-transplant hypercalcemia is a major problem in renal transplant recipients, which may negatively affect both graft and patient survival. In this paper, we present a 66-year-old male kidney transplant recipient, who was admitted to our clinic with symptoms of fever, nausea, vomiting and lethargy. Laboratory data showed good renal function; however, a serum calcium level of 22.1 mg/dL. The patient was treated by isotonic saline together with furosemide and methylprednisolone. Because of treatment resistance, subcutaneous calcitonin and ibandronate were added to the treatment protocol as well...
April 28, 2018: CEN Case Reports
https://www.readbyqxmd.com/read/29703635/differences-in-the-association-of-total-versus-local-coronary-artery-calcium-with-acute-coronary-syndrome-and-culprit-lesions-in-patients-with-acute-chest-pain-the-coronary-calcium-paradox
#17
Stefan B Puchner, Thomas Mayrhofer, Jakob Park, Michael T Lu, Ting Liu, Pal Maurovich-Horvat, Khristine Ghemigian, Daniel O Bittner, Jerome L Fleg, James E Udelson, Quynh A Truong, Udo Hoffmann, Maros Ferencik
BACKGROUND AND AIMS: Total coronary artery calcium (CAC) burden is associated with an increased cardiovascular risk, while local CAC may represent stable plaques. We determined differences in relationship of total CAC with acute coronary syndrome (ACS) and local CAC with culprit lesions in patients with suspected ACS. METHODS: We performed computed tomography (CT) for CAC and CT angiography to assess the presence of significant stenosis and high-risk plaque (positive remodeling, low CT attenuation, napkin-ring sign, spotty calcium) in 37 patients with ACS and 223 controls...
April 17, 2018: Atherosclerosis
https://www.readbyqxmd.com/read/29703129/lithium-incorporated-deproteinized-bovine-bone-substitute-improves-osteogenesis-in-critical-sized-bone-defect-repair
#18
Hongzhang Guo, Changde Wang, Jixiang Wang, Yufang He
This study aimed to explore the surface modification of deproteinized bovine bone using lithium-ion and evaluate its efficacy on osteogenesis improvement and critical-sized bone defect repair. Hydrothermal treatment was performed to produce lithium-incorporated deproteinized bovine bone. In vitro study, human osteosarcoma cell MG63 (MG63) was cultured with the bone substitute to evaluate the cell viability and then calcium deposition was measured to analyze the osteogenesis. In vivo studies, male adult goats were chosen to build critical-sized bone defect model and randomly divided into three groups...
May 2018: Journal of Biomaterials Applications
https://www.readbyqxmd.com/read/29699526/computerized-tomography-findings-in-calcified-signet-ring-gastric-cancer-receiving-chemotherapy-a-case-report
#19
Ting Wang, Zhi-Yong Lu, Xin-Fei Tu, Shui-Hong Zhang, Fang Huang, Long Huang
BACKGROUND: Calcification in primary gastric cancer is very rare. In this report, we describe the computerized tomography (CT) changes in calcification in a patient with locally advanced signet-ring gastric cancer treated with chemotherapy. CASE PRESENTATION: A 49-year-old man presented with 5 months' history of abdominal pain, anorexia, and rapid weight loss. He had undergone Billroth-II subtotal gastrectomy for a bleeding gastric ulcer 30 years ago. Abdominal CT showed irregular thickening of the gastric wall and miliary calcifications...
April 27, 2018: BMC Cancer
https://www.readbyqxmd.com/read/29698291/csa-90-promotes-bone-formation-and-mitigates-methicillin-resistant-staphylococcus-aureus-infection-in-a-rat-open-fracture-model
#20
Rebecca Mills, Tegan L Cheng, Kathy Mikulec, Lauren Peacock, David Isaacs, Carl Genberg, Paul B Savage, David G Little, Aaron Schindeler
BACKGROUND: Infection of open fractures remains a significant cause of morbidity and mortality to patients worldwide. Early administration of prophylactic antibiotics is known to improve outcomes; however, increasing concern regarding antimicrobial resistance makes finding new compounds for use in such cases a pressing area for further research. CSA-90, a synthetic peptidomimetic compound, has previously demonstrated promising antimicrobial action against Staphylococcus aureus in rat open fractures...
April 24, 2018: Clinical Orthopaedics and related Research
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