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https://www.readbyqxmd.com/read/28209366/quantifying-aortic-valve-calcification-using-coronary-computed-tomography-angiography
#1
Abdulrahman M Alqahtani, Kevin E Boczar, Vinay Kansal, Kwan Chan, Girish Dwivedi, Benjamin J W Chow
INTRODUCTION: Aortic valve calcification (AVC) has been associated with major adverse cardiovascular events and all-cause mortality. We sought to develop and validate a method to quantify AVC using coronary CT angiography (CTA). METHODS: Of 59 patients who underwent both non-contrast and contrast enhanced coronary CTA, 25 patients served as the derivation cohort and 34 patients served as the validation cohort. For non-contrast enhanced CT, quantification of AVC was performed using the Agatston method for coronary artery calcification (CAC)...
January 30, 2017: Journal of Cardiovascular Computed Tomography
https://www.readbyqxmd.com/read/28209099/does-calcium-score-in-great-pelvic-vessels-predict-colorectal-anastomotic-leakage-a-prospective-study-of-one-hundred-anastomoses
#2
M T Norooz, H Moradi, M Safdarian, F Jahangiri, H A Amoli
BACKGROUND: Anastomotic leakage is one of the most severe surgical complications following surgery. This prospective study was designed to investigate an association between the calcification in the descending aorta and its major branches using a calcium-scoring software and colorectal anastomotic leakage. METHODS: From January 2012 to March 2013, one hundred patients underwent surgeries involving colorectal anastomosis procedures. Calcium score in descending aorta and great pelvic vessels was measured using the Syngo-CT 2006G-W software...
September 2016: Acta Gastro-enterologica Belgica
https://www.readbyqxmd.com/read/28198975/short-term-sodium-alendronate-administration-improves-the-peri-implant-bone-quality-in-osteoporotic-animals
#3
Danila de Oliveira, Jaqueline Suemi Hassumi, Pedro Henrique da Silva Gomes-Ferreira, Tárik Ocon Braga Polo, Gabriel Ramalho Ferreira, Leonardo Perez Faverani, Roberta Okamoto
Objective: The aim of this study was to evaluate the bone repair process at the bone/implant interface of osteoporotic rats treated with sodium alendronate through the analysis of microtomography, real time polymerase chain reactions and immunohistochemistry (RUNX2 protein, bone sialoprotein (BSP), alkaline phosphatase, osteopontin and osteocalcin). Material and Methods: A total of 42 rats were used and divided in to the following experimental groups: CTL: control group (rats submitted to fictitious surgery and fed with a balanced diet), OST: osteoporosis group (rats submitted to a bilateral ovariectomy and fed with a low calcium diet) and ALE: alendronate group (rats submitted to a bilateral ovariectomy, fed with a low calcium diet and treated with sodium alendronate)...
January 2017: Journal of Applied Oral Science: Revista FOB
https://www.readbyqxmd.com/read/28193446/usefulness-of-calcium-scoring-as-a-screening-examination-in-patients-with-a-history-of-kawasaki-disease
#4
Andrew M Kahn, Matthew J Budoff, Lori B Daniels, Jun Oyamada, John B Gordon, Jane C Burns
Subsets of patients with a remote history of Kawasaki disease (KD) have coronary artery aneurysms with associated risks of late morbidity. In a pilot study, we previously showed that computed tomography (CT) coronary artery calcium (CAC) scoring detects late CAC in patients with aneurysms and a remote history of KD. We performed CT calcium volume scoring in 166 subjects (median age 19.5 years) with a remote history of KD (median interval from KD to CT 15.1 years). Coronary arteries were classified as normal (n = 100), transiently dilated (n = 23), persistently dilated (n = 10), remodeled aneurysm (n = 9), or aneurysm (n = 24) based on echocardiography...
January 6, 2017: American Journal of Cardiology
https://www.readbyqxmd.com/read/28188512/hepatic-abscess-in-the-spiegel-lobe-caused-by-foreign-body-penetration-report-of-a-case-report
#5
Yuki Fujiwara, Hiroaki Shiba, Yukio Nakabayashi, Masahiko Otsuka, Katsuhiko Yanaga
A 69-year-old male patient visited our hospital because of a continuous low-grade fever and right back pain since 2 weeks. Enhanced computed tomography (CT) of his abdomen revealed a mass with ring enhancement (35 × 30 mm) in the Spiegel lobe as well as a needle-like foreign body. Because conservative treatment by fasting and administration of antibiotics was unsuccessful, the patient underwent emergency laparotomy for removal of the foreign body and drainage of the liver abscess. The patient made a satisfactory postoperative recovery without complications and was discharged on the eighth postoperative day...
December 2017: Surgical Case Reports
https://www.readbyqxmd.com/read/28174198/the-puzzle-of-noninvasive-testing-in-women-filling-in-the-pieces-with-the-crescent-trial-calcium-imaging-and-selective-ct-angiography-in-comparison-to-functional-testing-for-suspected-coronary-artery-disease
#6
EDITORIAL
https://www.readbyqxmd.com/read/28174196/sex-differences-in-the-performance-of-cardiac-computed-tomography-compared-with-functional-testing-in-evaluating-stable-chest-pain-subanalysis-of-the-multicenter-randomized-crescent-trial-calcium-imaging-and-selective-ct-angiography-in-comparison-to-functional
#7
Marisa Lubbers, Adriaan Coenen, Tobias Bruning, Tjebbe Galema, Jurgen Akkerhuis, Boudewijn Krenning, Paul Musters, Mohamed Ouhlous, Ahno Liem, Andre Niezen, Admir Dedic, Ron van Domburg, Miriam Hunink, Koen Nieman
BACKGROUND: Cardiac computed tomography (CT) represents an alternative diagnostic strategy for women with suspected coronary artery disease, with potential benefits in terms of effectiveness and cost-efficiency. METHODS AND RESULTS: The CRESCENT trial (Calcium Imaging and Selective CT Angiography in Comparison to Functional Testing for Suspected Coronary Artery Disease) prospectively randomized 350 patients with stable angina (55% women; aged 55±10 years), mostly with an intermediate coronary artery disease probability, between cardiac CT and functional testing...
February 2017: Circulation. Cardiovascular Imaging
https://www.readbyqxmd.com/read/28171719/nano-hydroxyapatite-bone-substitute-functionalized-with-bone-active-molecules-for-enhanced-cranial-bone-regeneration
#8
Arun Kumar Teotia, Deepak Bushan Raina, Chandan Singh, Neeraj Sinha, Hanna Isaksson, Magnus Tagil, Lars Lidgren, Ashok Kumar
The aim of this study was to synthesize and characterize a nano-hydroxyapatite (nHAP) and calcium sulphate bone substitute (NC) for cranioplasty. The NC was functionalized with low concentrations of bone morphogenetic protein-2 (BMP-2) and zoledronic acid (ZA) and characterized both in vitro and in vivo. In vitro studies included MTT, ALP assays and fluorescent staining of Saos-2 (human osteoblasts) and MC3T3-e1 (murine pre-osteoblasts) cells cultured on NC. An in vivo study divided twenty male Wistar rats into four groups: control (defect only), NC, NC+ZA and NC+ZA+rhBMP-2...
February 7, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28170338/association-between-vitamin-d-receptor-gene-foki-polymorphism-and-skeletal-fluorosis-of-the-brick-tea-type-fluorosis-a-cross-sectional-case-control-study
#9
Dan Yang, Yang Liu, Yanru Chu, Qing Yang, Wei Jiang, Fuxun Chen, Dandan Li, Ming Qin, Dianjun Sun, Yanmei Yang, Yanhui Gao
BACKGROUND: Brick-tea type fluorosis is a public health concern in the north west area of China. The vitamin D receptor (VDR)-FokI polymorphism is considered to be a regulator of bone metabolism and calcium resorption. However, the association of VDR-FokI polymorphism with the risk of brick-tea type fluorosis has not been reported. MATERIALS AND METHODS: A cross sectional, case control study was conducted in three provinces (Inner Mongolia, Qinghai and Sinkiang) in China...
November 10, 2016: BMJ Open
https://www.readbyqxmd.com/read/28170301/influence-of-parathyroidectomy-on-bone-calcium-concentration-evaluation-with-spectral-ct-in-patients-with-secondary-hyperparathyroidism-undergoing-hemodialysis-a-prospective-feasibility-study
#10
Qiang Ma, Zhenghan Yang, Xue Han, Fen Liu, Dechun Su, Haidong Xing
Purpose To use spectral computed tomography (CT) to evaluate the influence of parathyroidectomy (PTX) on calcium concentration in trabecular bone and cortical bone in patients undergoing hemodialysis with secondary hyperparathyroidism. Materials and Methods This study was performed with institutional review board approval. Written consent was obtained from each patient. Thirty-eight men (mean age ± standard deviation, 55.69 years ± 8.05; range, 42-72 years) undergoing maintenance hemodialysis who underwent PTX and 40 patients (mean age, 56...
February 7, 2017: Radiology
https://www.readbyqxmd.com/read/28169348/the-internal-anatomy-of-titanosaur-osteoderms-from-the-upper-cretaceous-of-spain-is-compatible-with-a-role-in-oogenesis
#11
Daniel Vidal, Francisco Ortega, Francisco Gascó, Alejandro Serrano-Martínez, José Luis Sanz
Dermal armor is one of the most intriguing features of some titanosaurs, the only sauropod dinosaurs that bore osteoderms. Some studies have revealed cavities of varying sizes inside some titanosaur osteoderms, interpreted as the result of bone remodeling for mineral mobilization. Several hypotheses have been proposed to explain the need for mineral mobilization in titanosaurs. However, rejecting those hypotheses was difficult with hitherto available evidence. The Upper Cretaceous site of Lo Hueco (Cuenca; Spain) has yielded one of the largest titanosaur osteoderm sets available...
February 7, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28167282/comparison-of-low-dose-coronary-artery-calcium-scoring-using-low-tube-current-technique-and-hybrid-iterative-reconstruction-vs-filtered-back-projection
#12
Nada Sulaiman, Jeanette Soon, Jong Kwan Park, Christopher Naoum, Shaw-Hua Kueh, Philipp Blanke, Darra Murphy, Jennifer Ellis, Cameron J Hague, Jonathon Leipsic
INTRODUCTION: We sought to validate whether low dose CACS CT with hybrid IR (HIR) could replace standard dose filtered back projection (FBP). METHOD: We enrolled 100 patients to undergo low dose CACS CT with HIR, in addition to routine full dose FBP. RESULTS: No significant difference between full and low dose CT in Agatston score 138.2±360.6 vs. 137.3±356.4 (p=0.272) or calcium mass score 19±48.3 vs. 18.7±49 (p=0.8), respectively. Bland-Altman analysis showed no systematic bias...
February 2, 2017: Clinical Imaging
https://www.readbyqxmd.com/read/28165410/bone-mineral-density-mechanical-microstructural-properties-and-mineral-content-of-the-femur-in-growing-rats-fed-with-cactus-opuntia-ficus-indica-l-mill-cactaceae-cladodes-as-calcium-source-in-diet
#13
Ezequiel Hernández-Becerra, Elsa Gutiérrez-Cortez, Alicia Del Real, Alejandra Rojas-Molina, Mario Rodríguez-García, Efraín Rubio, Michelle Quintero-García, Isela Rojas-Molina
Mechanical, microstructural properties, mineral content and bone mineral density (BMD) of the femur were evaluated in growing rats fed with Opuntia ficus indica (L.) Mill. (Cactaceae) cladodes at different maturity stages as calcium source. Male weanling rats were fed with cladodes at early maturity stage (25 and 60 days of age, belonging to groups N-60 and N-200, respectively) and cladodes at late maturity stage (100 and 135 days of age, belonging to groups N-400 and N-600, respectively) for 6 weeks. Additionally, a control group fed with calcium carbonate as calcium source was included for comparative purposes...
February 4, 2017: Nutrients
https://www.readbyqxmd.com/read/28159116/development-of-a-new-biodegradable-operative-clip-made-of-a-magnesium-alloy-evaluation-of-its-safety-and-tolerability-for-canine-cholecystectomy
#14
Toshihiko Yoshida, Takumi Fukumoto, Takeshi Urade, Masahiro Kido, Hirochika Toyama, Sadaki Asari, Tetsuo Ajiki, Naoko Ikeo, Toshiji Mukai, Yonson Ku
BACKGROUND: Operative clips used to ligate vessels in abdominal operation usually are made of titanium. They remain in the body permanently and form metallic artifacts in computed tomography images, which impair accurate diagnosis. Although biodegradable magnesium instruments have been developed in other fields, the physical properties necessary for operative clips differ from those of other instruments. We developed a biodegradable magnesium-zinc-calcium alloy clip with good biologic compatibility and enough clamping capability as an operative clip...
January 31, 2017: Surgery
https://www.readbyqxmd.com/read/28150282/socioeconomic-status-relationship-with-coronary-artery-calcification-and-pericardial-fat
#15
Hussein A Nafakhi, Abdulameer Almosawi, Hasan Alnafakh, Widad Mousa
BACKGROUND: Little data currently exist supporting the correlation of socioeconomic status (SES) to markers of subclinical coronary atherosclerosis. The main aim was to investigate the relationship of SES measured by economic status and educational level with coronary artery calcification (CAC) and pericardial fat volume (PFV) assessed by multi-detector CT (MDCT). METHODS: Two hundred twenty consecutive patients with suspected coronary artery disease who underwent 64-slice MDCT angiography for assessment of coronary atherosclerosis were recruited between January 2014 and March 2015...
February 2, 2017: Kardiologia Polska
https://www.readbyqxmd.com/read/28144819/no-psychological-distress-in-sportsmen-aged-45%C3%A2-years-and-older-after-cardiovascular-screening-including-cardiac-ct-the-measuring-athlete-s-risk-of-cardiovascular-events-marc-study
#16
M M Schurink, T L Braber, N H J Prakken, P A F M Doevendans, F J G Backx, D E Grobbee, R Rienks, H M Nathoe, M L Bots, B K Velthuis, A Mosterd
BACKGROUND: Psychological distress caused by cardiovascular pre-participation screening (PPS) may be a reason not to implement a PPS program. We assessed the psychological impact of PPS, including cardiac computed tomography (CT), in 318 asymptomatic sportsmen aged ≥45 years. METHODS: Coronary artery disease (CAD) was defined as a coronary artery calcium score ≥100 Agatson units and/or ≥50% luminal stenosis on contrast-enhanced cardiac CT. Psychological impact was measured with the Impact of Event Scale (IES) (seven items) on a six-point scale (grade 0-5)...
January 31, 2017: Netherlands Heart Journal
https://www.readbyqxmd.com/read/28139306/acute-neck-pain-in-the-emergency-department-consider-longus-colli-calcific-tendinitis-vs-meningitis
#17
Tyag K Patel, James C Weis
Presented here is a rare cause of severe neck pain - acute longus colli calcific tendinitis - in a 54year old man who presented to the emergency department. The neck pain is due to inflammation caused by calcium hydroxyapatite crystal deposition in the tendons on the longus colli muscles. This is non-infectious. The gold standard for diagnosis is a CT neck which best shows the calcifications in the anterior vertebral column of C1-C4, where the tendons of these muscles insert bilaterally. Longus colli calcific tendinitis is not life-threatening and patients will make a full recovery after treatment with NSAIDs...
January 25, 2017: American Journal of Emergency Medicine
https://www.readbyqxmd.com/read/28130653/addressing-knowledge-gaps-in-the-2013-acc-aha-guideline-on-the-assessment-of-cardiovascular-risk-a-review-of-recent-coronary-artery-calcium-literature
#18
REVIEW
Vasanth Sathiyakumar, Roger S Blumenthal, Khurram Nasir, Seth S Martin
PURPOSE OF REVIEW: Coronary artery calcium (CAC) has been proposed as an integrator of information from traditionally measured, non-traditionally measured, and unmeasured risk factors for coronary atherosclerosis. The 2013 American College of Cardiology/American Heart Association Guideline on the Assessment of Cardiovascular Risk identified several knowledge gaps regarding CAC, including radiation risks, cost-effectiveness, and improving discrimination and reclassification of estimated risk over the Pooled Cohort Equations in the ACC/AHA Atherosclerotic Cardiovascular Disease Estimator...
February 2017: Current Atherosclerosis Reports
https://www.readbyqxmd.com/read/28130124/calcium-modulates-calmodulin-%C3%AE-actinin-1-interaction-with-and-agonist-dependent-internalization-of-the-adenosine-a2a-receptor
#19
Henni Piirainen, Jaume Taura, Petri Kursula, Francisco Ciruela, Veli-Pekka Jaakola
Adenosine receptors are G protein-coupled receptors that sense extracellular adenosine to transmit intracellular signals. One of the four adenosine receptor subtypes, the adenosine A2A receptor (A2AR), has an exceptionally long intracellular C terminus (A2AR-ct) that mediates interactions with a large array of proteins, including calmodulin and α-actinin. Here, we aimed to ascertain the α-actinin 1/calmodulin interplay whilst binding to A2AR and the role of Ca(2+) in this process. First, we studied the A2AR-α-actinin 1 interaction by means of native polyacrylamide gel electrophoresis, isothermal titration calorimetry, and surface plasmon resonance, using purified recombinant proteins...
January 24, 2017: Biochimica et Biophysica Acta
https://www.readbyqxmd.com/read/28123741/hepatocellular-carcinoma-with-inferior-vena-caval-and-right-atrial-tumor-thrombi-and-massive-pulmonary-artery-embolism-a-case-report
#20
Jian Huang, Ze-Ya Pan, Li Li, Bei-Ge Jiang, Fang-Ming Gu, Zhen-Guang Wang, Zhi-Hong Wang, Wei-Ping Zhou
The aim of the present study was to report the case of a 55-year-old female patient with a sizeable (7.1×6.2 cm) hepatocellular carcinoma (HCC), who succumbed to massive pulmonary artery embolism. The main symptoms included sudden thoracodynia, dyspnea and transient coma. The initial diagnosis was HCC according to the typical abdominal ultrasound and triple-phase abdominal computed tomography (CT) findings, chronic hepatitis B infection and elevated α-fetoprotein levels (1,036 µg/l; normal, 0-20 µg/l). Two days following admission, the patient developed recurrent chest pain and shortness of breath...
January 2017: Molecular and Clinical Oncology
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