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https://www.readbyqxmd.com/read/28341247/toxicological-evaluation-of-oviductus-ranae-acute-sub-acute-and-genotoxicity-studies-in-mice-and-rats
#1
Yang Zhang, Kun Zhu, Hao Cui, Yang Liu, Ye-Fang Lu, Hong-Wei Pan, He-Peng Zhao, Ling Qi, Xiu-Dong Yang, Hong-Li Zhou
ETHNOPHARMACOLOGICAL RELEVANCE: Oviductus ranae (OR) is a traditional animal-based Chinese medicine, which has been listed in the Chinese Pharmacopoeia since 1985 edition. Although its medicinal application has been widely acknowleged, there is little available information on its potential toxicity. AIM OF THE STUDY: The aim of this study was to investigate the acute, sub-acute, and genetic toxicities of OR. MATERIALS AND METHODS: In acute toxicity evaluation, OR was administered orally to mice at doses of 2...
March 21, 2017: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/28339631/evidence-for-the-involvement-of-the-proximal-copy-of-the-magea9-gene-in-xq28-linked-cnv67-specific-to-spermatogenic-failure%C3%A2
#2
Ying Shen, Jinyan Xu, Xiling Yang, Yunqiang Liu, Yongyi Ma, Dong Yang, Qiang Dong, Yuan Yang
Spermatogenic failure characterized by impaired sperm production is a common multifactorial disease with molecular and cytogenetic causes for its extreme phenotype that include azoospermia and severe oliogzoospermia. Recently, a high-resolution array-comparative genomic hybridization analysis of the X chromosome and a subsequent cohort study revealed three X-linked microdeletions (CNV64, CNV67, and CNV69) that were associated with decreased sperm production in a mixed group that included Spanish and Italian males...
February 7, 2017: Biology of Reproduction
https://www.readbyqxmd.com/read/28278362/testing-the-phenotype-linked-fertility-hypothesis-in-the-presence-and-absence-of-inbreeding
#3
Wolfgang Forstmeier, Malika Ihle, Pavlína Opatová, Katrin Martin, Ulrich Knief, Jana Albrechtová, Tomáš Albrecht, Bart Kempenaers
The phenotype-linked fertility hypothesis suggests that females can judge male fertility by inspecting male phenotypic traits. This is because male sexually selected traits might correlate with sperm quality if both are sensitive to factors that influence male condition. A recent meta-analysis found little support for this hypothesis, suggesting little or no shared condition dependence. However, we recently reported that in captive zebra finches (Taeniopygia guttata) inbreeding had detrimental effects both on phenotypic traits and on measures of sperm quality, implying that variation in inbreeding could induce positive covariance between indicator traits and sperm quality...
March 9, 2017: Journal of Evolutionary Biology
https://www.readbyqxmd.com/read/28178993/perspectives-of-urban-ghanaian-women-on-vasectomy
#4
Ofeibea Asare, Easmon Otupiri, Joana Apenkwa, Rose Odotei-Adjei
BACKGROUND: Advocacy for male involvement in family planning has been championed over the years after the 1994 International Conference on Population and Development (ICPD). There are a few contraceptive methods for men, and vasectomy uptake has been identified as one of the indicators of male involvement in family planning. Vasectomy also known as male sterilization is a permanent form of contraception. It is a generally safe, quick, easy, effective surgical operation with rare complications to prevent release of sperm...
February 8, 2017: Reproductive Health
https://www.readbyqxmd.com/read/28171687/seminal-coagulation-and-sperm-quality-in-different-social-contexts-in-captive-tufted-capuchin-monkeys-sapajus-apella
#5
Julianne S Lima, Danuza L Leão, Karol G Oliveira, Adriel B Brito, Wlaisa V Sampaio, Regiane R Santos, Helder L Queiroz, Sheyla F Domingues
In the present study, we aimed to assess the influence of different social contexts on the seminal coagulation and sperm quality in captive tufted capuchin monkeys. For this, males were housed either individually, in mixed-sex groups (with females), or in male-only groups. Monkeys were housed in cages and each cage type (i.e., individual or group cage) was placed in a different room. Forty-one males were subjected to semen collection by rectal electroejaculation. The degree of seminal coagulation was determined on a scale of I-IV...
February 7, 2017: American Journal of Primatology
https://www.readbyqxmd.com/read/28128993/environmental-factors-contributed-to-circannual-rhythm-of-semen-quality
#6
Huan Mao, Lei Feng, Wan-Xi Yang
We investigated whether human semen parameters present circannual rhythm or not, and whether environmental factors exert on semen quality. This retrospective study used data of patients mainly from Reproductive Medicine Center and Urology and Andrology Clinic of a general hospital in China. Sperm concentration and motility were measured by computer aided sperm analysis (CASA). Sperm morphology was scored based on the strict criteria (WHO, 2010). The Kruskal-Wallis rank test was used to investigate the relationship between semen parameters and season/month...
2017: Chronobiology International
https://www.readbyqxmd.com/read/28126553/korean-red-ginseng-improves-testicular-ineffectiveness-in-aging-rats-by-modulating-spermatogenesis-related-molecules
#7
Spandana Rajendra Kopalli, Kyu-Min Cha, Ji-Hoon Ryu, Sang-Ho Lee, Min-Sik Jeong, Seock-Yeon Hwang, Young-Joo Lee, Hee-Won Song, Su-Nam Kim, Jin-Chul Kim, Si-Kwan Kim
Korean red ginseng (Panax ginseng Meyer) is known to rejuvenate testicular effectiveness and the sperm maturation process by regulating redox proteins in aged rats. This study was performed to investigate the effect of Korean red ginseng water extract (KRG-WE) on the expression level of spermatogenesis-related key biomolecules and sex hormone receptors as well as enzymes regulating oxidation, histone deacetylation, and growth-related activities in aged rat testis. KRG-WE (200mg/kg) mixed with a regular pellet diet was administered to 12-month-old rats for 6months (KRG-AC), whereas the young (YC, 2months) and aged (AC, 12months) controls received the vehicle only...
April 2017: Experimental Gerontology
https://www.readbyqxmd.com/read/28104697/male-birthweight-semen-quality-and-birth-outcomes
#8
B W Whitcomb, M S Bloom, S Kim, Z Chen, G M Buck Louis
STUDY QUESTION: What are the relations among birthweight (BW), semen parameters and birth outcomes in a population-based sample? SUMMARY ANSWER: BW is unrelated to semen parameters, which are in turn unrelated to birth outcomes. WHAT IS KNOWN ALREADY: In clinical settings, there has been suggestion that semen parameters are related to BW when comparing fertile and infertile men; however, findings have been less clear in more general populations...
January 18, 2017: Human Reproduction
https://www.readbyqxmd.com/read/28078758/periconceptional-maternal-high-fish-and-olive-oil-low-meat-dietary-pattern-is-associated-with-increased-embryonic-growth-the-rotterdam-periconceptional-cohort-predict-study
#9
Francesca Parisi, Melek Rousian, Nicole A Huijgen, Anton H J Koning, Sten P Willemsen, Jeanne H M de Vries, Irene Cetin, Eric A P Steegers, Régine P M Steegers-Theunissen
OBJECTIVE: To investigate associations between periconceptional maternal dietary patterns and first trimester embryonic growth. METHODS: 228 women with singleton ongoing pregnancies were enrolled in a prospective periconceptional cohort study, comprising of 135 strictly dated spontaneous pregnancies and 93 pregnancies achieved after in vitro fertilization or intracytoplasmatic sperm injection (IVF/ICSI pregnancies). All women underwent longitudinal transvaginal three-dimensional ultrasound (3D-US) scans from 6(+0) up to 13(+0) weeks of gestation...
January 12, 2017: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/28028016/multiple-and-asymmetrical-origin-of-polyploid-dog-rose-hybrids-rosa-l-sect-caninae-dc-ser-involving-unreduced-gametes
#10
V Herklotz, C M Ritz
BACKGROUND AND AIMS: Polyploidy and hybridization are important factors for generating diversity in plants. The species-rich dog roses (Rosa sect. Caninae) originated by allopolyploidy and are characterized by unbalanced meiosis producing polyploid egg cells (usually 4x) and haploid sperm cells (1x). In extant natural stands species hybridize spontaneously, but the extent of natural hybridization is unknown. The aim of the study was to document the frequency of reciprocal hybridization between the subsections Rubigineae and Caninae with special reference to the contribution of unreduced egg cells (5x) producing 6x offspring after fertilization with reduced (1x) sperm cells...
December 27, 2016: Annals of Botany
https://www.readbyqxmd.com/read/28012719/cysteamine-supplementation-revealed-detrimental-effect-on-cryosurvival-of-buffalo-sperm-based-on-computer-assisted-semen-analysis-and-oxidative-parameters
#11
Dheer Singh Swami, Pradeep Kumar, R K Malik, Monika Saini, Dharmendra Kumar, M H Jan
The aim of this study was to investigate the effect of addition of cysteamine to the semen extender on post-thaw semen quality. A total of 30 ejaculates were collected from six bulls. Each ejaculate was divided into five equal parts and diluted to final concentration of 80 million sperms/mL using Optixcell(®)(IMV, France) semen extender supplemented with different concentrations of cysteamine (0, 0.75, 1.25, 2.5 and 5mM) and cryopreserved. In the frozen-thawed samples, the VAP, VSL, VCL ALH and sperm motility of control samples was greater (P<0...
February 2017: Animal Reproduction Science
https://www.readbyqxmd.com/read/27939508/time-lapse-morphokinetic-assessment-has-low-to-moderate-ability-to-predict-euploidy-when-patient-and-ovarian-stimulation-related-factors-are-taken-into-account-with-the-use-of-clustered-data-analysis
#12
Sezcan Mumusoglu, Irem Yarali, Gurkan Bozdag, Pınar Ozdemir, Mehtap Polat, Lale Karakoc Sokmensuer, Hakan Yarali
OBJECTIVE: To study whether time-lapse morphokinetic (TLM) assessment predicts ploidy status when patient- and ovarian stimulation-related factors are taken into account. DESIGN: Retrospective cohort study. SETTING: Private IVF clinic. PATIENT(S): In total, 103 consecutive patients (415 blastocysts) were included. All embryos were individually cultured in a time-lapse incubator from intracytoplasmic sperm injection up to trophectoderm biopsy...
February 2017: Fertility and Sterility
https://www.readbyqxmd.com/read/27932246/denaturing-action-of-adjuvant-affects-specificity-of-polyclonal-antibodies
#13
K V Barinova, E V Khomyakova, M L Kuravsky, E V Schmalhausen, V I Muronetz
Influence of the immunization procedure on the specificity of the produced antibodies towards different conformations of the antigen was investigated. It was demonstrated that intravenous immunization of a rabbit with an adjuvant-free solution of recombinant sperm-specific glyceraldehyde-3-phosphate dehydrogenase (dN-GAPDS) resulted in production of antibodies recognizing only native conformation of dN-GAPDS and exhibiting no cross-reaction with somatic isoenzyme of glyceraldehyde-3-phosphate dehydrogenase...
January 22, 2017: Biochemical and Biophysical Research Communications
https://www.readbyqxmd.com/read/27888150/coenzyme-q10-intake-from-food-and-semen-parameters-in-a-subfertile-population
#14
Bruno C Tiseo, Audrey J Gaskins, Russ Hauser, Jorge E Chavarro, Cigdem Tanrikut
OBJECTIVE: To assess the association between coenzyme Q10 (CoQ10) intake from food sources and semen quality. We assessed this association in a prospective cohort of men attending a fertility clinic. CoQ10 supplementation has been associated with improvements in semen parameters. However, the impact of CoQ10 intake from food sources on semen quality has not been investigated. MATERIALS AND METHODS: Subfertile couples seeking fertility evaluation at the Massachusetts General Hospital Fertility Center were invited to participate in an ongoing study of environmental factors and fertility...
November 22, 2016: Urology
https://www.readbyqxmd.com/read/27876951/prevalence-of-dermanyssus-and-ornithonyssus-species-of-mites-in-poultry-farms-of-vikarabad-area-of-hyderabad
#15
G S Sreenivasa Murthy, Rasmita Panda
The common blood feeder mites of poultry are from the genera Dermanyssus and Ornithonyssus. Their presence are problematic for the producers either through potential direct effects on weight gain, egg production or sperm production in roosters or as nuisance pests on workers. They also cause anaemia in birds and play a vector role for several human and animal diseases. Five poultry farm buildings of Vikarabad area of Rangareddy district were visited. Samples were collected from a variety of sites, including beneath feed troughs, inside cage fittings and fastening clips, under egg conveyer belts and under manure belts...
December 2016: Journal of Parasitic Diseases: Official Organ of the Indian Society for Parasitology
https://www.readbyqxmd.com/read/27866723/association-between-ambient-particulate-matter-exposure-and-semen-quality-in-wuhan-china
#16
Li Wu, Lei Jin, Tingming Shi, Bing Zhang, Yun Zhou, Ting Zhou, Wei Bao, Hua Xiang, Yao Zuo, Guanlian Li, Cheng Wang, Yonggang Duan, Zhe Peng, Xiji Huang, Hai Zhang, Tian Xu, Yonggang Li, Xinyun Pan, Ying Xia, Xun Gong, Weihong Chen, Yuewei Liu
BACKGROUND: Health effects of exposure to particulate matter (PM) on male reproductive health remain unclear. Only a limited number of studies have investigated the effects of PM2.5 or PM10 exposure on semen quality, and the results were largely inconsistent. OBJECTIVES: To quantitatively assess the exposure-response association between PM exposure and semen quality in Chinese men who were exposed to a wide concentration range of PM. METHODS: We investigated 1759 men from Wuhan, China, who were partners of women undergoing assisted reproductive technology procedures, and had semen examined at least once between 2013 and 2015...
November 17, 2016: Environment International
https://www.readbyqxmd.com/read/27865449/characterizing-nuclear-and-mitochondrial-dna-in-spent-embryo%C3%A2-culture-media-genetic-contamination-identified
#17
Elizabeth R Hammond, Brent C McGillivray, Sophie M Wicker, John C Peek, Andrew N Shelling, Peter Stone, Larry W Chamley, Lynsey M Cree
OBJECTIVE: To characterize nuclear and mitochondrial DNA (mtDNA) in spent culture media from normally developing blastocysts to determine whether it could be used for noninvasive genetic assessment. DESIGN: Prospective embryo cohort study. SETTING: Academic center and private in vitro fertilization (IVF) clinic. PATIENT(S): Seventy patients undergoing intracytoplasmic sperm injection (ICSI) and 227 blastocysts. INTERVENTION(S): Culture media assessment, artificial blastocoele fluid collapse and DNA analysis using digital polymerase chain reaction (dPCR), long-range PCR, quantitative PCR (qPCR), and DNA fingerprinting...
January 2017: Fertility and Sterility
https://www.readbyqxmd.com/read/27857155/fluorescence-and-magnetic-activated-cell-sorting-strategies-to-separate-spermatozoa-involving-plural-contributors-from-biological-mixtures-for-human-identification
#18
Yan Xu, Jianhui Xie, Ronghua Chen, Yu Cao, Yuan Ping, Qingwen Xu, Wei Hu, Dan Wu, Lihua Gu, Huaigu Zhou, Xin Chen, Ziqin Zhao, Jiang Zhong, Rui Li
No effective method has been developed to distinguish sperm cells originating from different men in multi-suspect sexual assault cases. Here we combined MACS and FACS to isolate single donor sperm cells from forensic mixture samples including female vaginal epithelial cells and sperm cells from multiple contributors. Sperms from vaginal swab were isolated by MACS using FITC-conjugated A kinase anchor protein 3 (AKAP3) antibody; target individual sperm cells involving two or three donors were separated by FACS using FITC-labeled blood group A/B antigen antibody...
November 18, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27809479/designing-micro-and-nanoswimmers-for-specific-applications
#19
Jaideep Katuri, Xing Ma, Morgan M Stanton, Samuel Sánchez
Self-propelled colloids have emerged as a new class of active matter over the past decade. These are micrometer sized colloidal objects that transduce free energy from their surroundings and convert it to directed motion. The self-propelled colloids are in many ways, the synthetic analogues of biological self-propelled units such as algae or bacteria. Although they are propelled by very different mechanisms, biological swimmers are typically powered by flagellar motion and synthetic swimmers are driven by local chemical reactions, they share a number of common features with respect to swimming behavior...
January 17, 2017: Accounts of Chemical Research
https://www.readbyqxmd.com/read/27800030/fertility-preservation-in-males-with-cancer-16-year-monocentric-experience-of-sperm-banking-and-post-thaw-reproductive-outcomes
#20
Raffaella Depalo, Doriana Falagario, Paola Masciandaro, Claudia Nardelli, Margherita Patrizia Vacca, Pasquale Capuano, Giorgina Specchia, Michele Battaglia
BACKGROUND: Anticancer treatments can impair male fertility. Cryopreservation of semen is an efficient procedure for fertility preservation. The aim of this study was to evaluate pre-freeze semen parameters among the various types of cancer, post-thaw sperm viability and reproductive outcome of samples used for assisted reproductive treatment (ART). METHODS: This study included 721 men with cancer that had their semen cryopreserved in our bank in 1999-2015. Semen analysis and cryopreservation were performed before the start of antineoplastic treatment, according to the World Health Organization recommendations, European Commission and Italian law...
November 2016: Therapeutic Advances in Medical Oncology
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