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Oral abscess

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https://www.readbyqxmd.com/read/28812940/odontogenic-orbital-abscess-with-intracranial-and-pulmonary-involvement
#1
E Hughes, N Wynne, S Quinn, T Fulcher
A 58-year-old woman presented to the emergency department with left ptosis and complete ophthalmoplegia. Imaging demonstrated a left orbital abscess. Her past medical history included cavitatory lung disease and "aseptic" meningitis 2 months previously. An anaerobic organism and commensal of the oral flora, Peptostreptococcus sp., was cultured from the orbital abscess. The patient was found to have a carious upper molar with chronic buccal abscess, which was extracted. This case presents an uncommon pathogen arising from an odontogenic infection as the etiology for orbital abscess, cavitatory lung disease, and meningitis in one patient...
August 16, 2017: Orbit
https://www.readbyqxmd.com/read/28812417/lacrimal-gland-abscesses-case-series-and-literature-review
#2
Brian Savoie, Rand Rodgers, Matthew Gorski
Acute dacryoadenitis with abscess formation has been rarely described. We describe four cases that resolved with incision and drainage. This includes a retrospective case series of four patients with radiologically confirmed lacrimal gland abscesses and a review of the reported cases in the literature. Computed tomography showed characteristic rim enhancing collections with central attenuation in all four cases. All patients presented with ptosis, upper eyelid erythema, and severe pain similar to scleritis...
August 16, 2017: Orbit
https://www.readbyqxmd.com/read/28807913/reducing-antibacterial-development-risk-for-gsk1322322-by-exploring-potential-human-dose-regimens-in-nonclinical-efficacy-studies-using-immunocompetent-rats
#3
Jennifer L Hoover, Christine M Singley, Philippa Elefante, Peter DeMarsh, Magdalena Zalacain, Stephen Rittenhouse
Directly testing proposed clinical dosing regimens in nonclinical studies can reduce risk during the development of novel antibacterial agents. Optimal dosing regimens can be identified in animal models by testing recreated human pharmacokinetic profiles. An example of this approach is presented using continuous intravenous infusions of GSK1322322 in immunocompetent rats to evaluate recreated Phase 1 human exposures in pneumonia models with Streptococcus pneumoniae and Haemophilus influenzae and an abscess model with Staphylococcus aureus GSK1322322 was administered via continuous intravenous infusion to recreate 1000 or 1500 mg oral doses every 12h in humans...
August 14, 2017: Antimicrobial Agents and Chemotherapy
https://www.readbyqxmd.com/read/28807049/oral-manifestations-dental-management-and-a-rare-homozygous-mutation-of-the-prdm12-gene-in-a-boy-with-hereditary-sensory-and-autonomic-neuropathy-type-viii-a-case-report-and-review-of-the-literature
#4
Karim Elhennawy, Seif Reda, Christian Finke, Luitgard Graul-Neumann, Paul-Georg Jost-Brinkmann, Theodosia Bartzela
BACKGROUND: Hereditary sensory and autonomic neuropathy type VIII is a rare autosomal recessive inherited disorder. Chen et al. recently identified the causative gene and characterized biallelic mutations in the PR domain-containing protein 12 gene, which plays a role in the development of pain-sensing nerve cells. Our patient's family was included in Chen and colleagues' study. We performed a literature review of the PubMed library (January 1985 to December 2016) on hereditary sensory and autonomic neuropathy type I to VIII genetic disorders and their orofacial manifestations...
August 15, 2017: Journal of Medical Case Reports
https://www.readbyqxmd.com/read/28771743/laryngeal-abscess-formation-in-an-immunosuppressed-patient-a-case-report
#5
Derek L Vanhille, Joel H Blumin
Prior to the onset of the antibiotic era, laryngeal perichondritis and abscess formation were more frequent complications of systemic infections. We report a case of 54-year-old male who was medically immunosuppressed after kidney transplantation and developed multiple pseudomonas abscesses of his larynx. After failing initial treatment and with worsening signs and symptoms, the patient eventually was treated with a prolonged course of intravenous and oral antibiotics, with resolution of his symptoms and clinical findings...
August 3, 2017: Laryngoscope
https://www.readbyqxmd.com/read/28770694/brain-abscesses-in-children-an-italian-multicentre-study
#6
I Raffaldi, S Garazzino, G Castelli Gattinara, R Lipreri, L Lancella, S Esposito, A M Giannini, C Montagnani, G L Marseglia, C Pignata, F Bernardi, P-A Tovo
Brain abscess is uncommon in paediatric population, but of clinical importance because of significant long-term morbidity and mortality. In this multicentre study, promoted by the Italian Society for Paediatric Infectious Diseases, we retrospectively collected patients aged 0-18 years, with a diagnosis of 'brain abscess'. Seventy-nine children were included; the median age was 8·75 years. As predisposing factor, 44 children had preceding infections. The Gram-positive cocci were mostly isolated (27 cases). Sixty (76%) children underwent a surgical intervention...
August 3, 2017: Epidemiology and Infection
https://www.readbyqxmd.com/read/28765482/the-non-resolving-lung-cavity-a-case-of-pulmonary-cystic-echinococcosis
#7
Simon Mifsud, Emma Louise Schembri, Jonathan Gauci, Adrian Mizzi, Charles Mallia Azzopardi, Josef Micallef
The authors report a case of a 20-year-old woman who was diagnosed with pulmonary cystic echinococcosis. She was admitted to hospital with a 1-week history of unresolving cough, coloured sputum with occasional haemoptysis and fever despite oral antibiotics. Radiology revealed a cavitating right lower lobe lung abscess. After 4 weeks of treatment, follow-up radiology showed incomplete resolution. Bronchoscopy revealed a white, avascular cystic lesion in the right lower lobe and serology testing for Echinococcus granulosus was positive...
July 31, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28744872/antibiotic-prescription-for-endodontic-infections-a-survey-of-brazilian-endodontists
#8
M R Bolfoni, F G Pappen, T Pereira-Cenci, R C Jacinto
AIM: To investigate antibiotic prescribing habits reported by Brazilian Endodontists in specific clinical situations. METHODOLOGY: Brazilian endodontists (n=13,853) were invited to answer an on-line questionnaire. The questionnaire consisted of two parts: the first part contained personal data such as age, gender, years of experience and location of endodontic practice; the second part included questions regarding dentists' behavior when prescribing antibiotics in dental practice...
July 26, 2017: International Endodontic Journal
https://www.readbyqxmd.com/read/28740959/idiopathic-granulomatous-mastitis-an-institutional-experience
#9
Seetharam Prasad, Padmapriya Jaiprakash, Aniket Dave, Deepti Pai
OBJECTIVE: To study idiopathic granulomatous mastitis with respect to its various clinical features, etiologic factors, treatment modalities and complications. MATERIAL AND METHODS: Retrospective study of all patients who were diagnosed with idiopathic granulomatous mastitis from 1(st) January 2006 to 31(st) December 2014 at Kasturba Hospital, Manipal, India (a tertiary care referral centre). The research was performed according to the World Medical Association Declaration of Helsinki...
2017: Turk J Surg
https://www.readbyqxmd.com/read/28738795/is-surgical-excision-necessary-for-the-treatment-of-granulomatous-lobular-mastitis
#10
Young Duck Shin, Sung Su Park, Young Jin Song, Seung-Myoung Son, Young Jin Choi
BACKGROUND: We aimed to investigate the role of surgical excision in treating granulomatous lobular mastitis. METHODS: We performed a retrospective chart review of patients with granulomatous lobular mastitis treated from March 2008 to March 2014. We analyzed clinical features and therapeutic modalities and compared the patient outcomes based on treatment. RESULTS: During the study period, a total of 34 patients were diagnosed with granulomatous lobular mastitis and treated...
July 24, 2017: BMC Women's Health
https://www.readbyqxmd.com/read/28735270/subcutaneous-levetiracetam-for-the-management-of-seizures-at-the-end-of-life
#11
REVIEW
Anna Elizabeth Sutherland, John Curtin, Victoria Bradley, Olivia Bush, Maggie Presswood, Victoria Hedges, Katrien Naessens
OBJECTIVES: To report the results of a combined case series analysis of subcutaneous levetiracetam (Keppra) for the management of seizures in palliative care patients. METHODS: A comprehensive literature review on the use of subcutaneous levetiracetam was performed, and these data were combined with a prospective observational audit of its use in terminal care undertaken in a regional palliative care network. RESULTS: 7 papers were identified from the literature review-four case reports and three observational case series-reporting on a total of 53 cases where subcutaneous levetiracetam was administered...
July 22, 2017: BMJ Supportive & Palliative Care
https://www.readbyqxmd.com/read/28720045/neonatal-acute-paronychia
#12
Luke Grome, Gregory Borah
BACKGROUND: Paronychia is defined as infection afflicting the eponychial nail folds of the hand or foot. Such infections are rarely reported in the perinatal age group, and not previously described in a neonate younger than 2 weeks. Trauma resulting in inoculation of the nail fold is the most common predisposing factor to paronychia. Oral trauma in the pediatric population from finger sucking predisposes this population to a different set of bacterial pathogens than adults. Contamination can progress to infection and abscess formation within the nail fold with the most prevalent vector in adult infections being Staphylococcus aureus...
February 1, 2017: Hand: Official Journal of the American Association for Hand Surgery
https://www.readbyqxmd.com/read/28719483/difficult-intubation-and-ventilation-in-an-infant-with-retropharyngeal-abscess-with-mediastinal-extension
#13
Michael A Bruno, Tomas Drabek, Mioara D Manole
A previously healthy 7-month-old male infant presented for evaluation of fever, deceased oral intake, and intermittent noisy breathing. Physical examination revealed neck tenderness. Soft tissue neck radiographs and computed tomography (CT) scan supported a diagnosis of retropharyngeal swelling with extension to the superior mediastinum. Surgical exploration was planned, and endotracheal intubation was performed in the operating room. Significant cardiorespiratory derangements developed immediately after the tracheal tube was inserted, including hypotension, hypoxia, and bradycardia with signs of cardiac ischemia...
July 17, 2017: Pediatric Emergency Care
https://www.readbyqxmd.com/read/28717908/systematic-review-and-meta-analysis-of-laparoscopic-versus-open-appendicectomy-in-adults-with-complicated-appendicitis-an-update-of-the-literature
#14
Christos Athanasiou, Sonia Lockwood, Georgios A Markides
AIMS: To review and compare the outcomes of laparoscopic (LA) versus open appendicectomy (OA) in complicated appendicitis in adult patients, eight years after the last literature review. METHODS: The PRISMA guidelines were adhered to. Pre-defined inclusion and exclusion criteria were used to search the PubMed, Scopus and Cochrane databases and extract relevant data. Methodological and quality assessment was undertaken with outcome meta-analysis and subgroup analyses of methodological quality, type of study and year of study...
July 17, 2017: World Journal of Surgery
https://www.readbyqxmd.com/read/28715092/the-origins-of-oral-medicine-in-the-hippocratic-collected-works
#15
REVIEW
Helen Askitopoulou, Vasileia Nyktari, Alexandra Papaioannou, Georgios Stefanakis, Elina Konsolaki
The collected works of Hippocrates describe for the first time in a systematic way a large number of oral diseases, such as ulcers, inflammations, abscesses and tumours from the epiglottis, mouth, tongue, palate, uvula and the sublingual area. Several of these case reports are remarkable for the accurate observation of clinical symptoms and signs, the aetiology, the pathogenesis and their therapeutic approach in relation to prognosis. The Hippocratic authors report cases of 'aphthae' as part of a polysystemic disease, described many centuries later by Behçet and Adamantiades, while they associate features of splenomegaly from endemic malaria with gingivitis ('ulitis')...
July 17, 2017: Journal of Oral Pathology & Medicine
https://www.readbyqxmd.com/read/28706854/nocardia-beijingensis-brain-abscesses-in-an-hiv-infected-individual
#16
Jolie Guevara Keenan, Sunita Mohapatra
We describe a case of a 50-year-old Hispanic man diagnosed with HIV/AIDS who presented with a generalized tonic clonic seizure and ring enhancing cerebral lesions on imaging. He was initially treated for CNS toxoplasmosis but presented to the hospital with another tonic clonic seizure despite prescribed therapy. Brain biopsy was performed which revealed Nocardia beijingensis. He was treated with intravenous meropenem and trimethoprim/sulfamethoxazole for six weeks followed by long term oral trimethoprim/sulfamethoxazole with radiographic and clinical improvement...
2017: IDCases
https://www.readbyqxmd.com/read/28693407/patterns-of-drugs-prescribed-for-dental-outpatients-in-nigeria-findings-and-implications
#17
Joseph O Fadare, Kazeem A Oshikoya, Obitade S Obimakinde, Abayomi O Sijuade, Jide M Afolayan, Adeyinka A Adeleke, Brian Godman, Damilola O Ojumu
OBJECTIVES: There are concerns with inappropriate prescribing of medicines among dentists especially antimicrobials. It is more concerning if this increases resistance rates. This study aimed to address this by assessing patterns of drugs prescribed for outpatients attending a hospital dental clinic in Nigeria. The findings will be used to plan future interventions, particularly around antimicrobial prescribing, where there are concerns. METHODS AND MATERIALS: Medical records of patients attending the dental clinic of a leading teaching hospital in Nigeria were evaluated...
July 11, 2017: Acta Odontologica Scandinavica
https://www.readbyqxmd.com/read/28692641/poor-efficacy-of-preemptive-amoxicillin-clavulanate-for-preventing-secondary-infection-from-bothrops-snakebites-in-the-brazilian-amazon-a-randomized-controlled-clinical-trial
#18
RANDOMIZED CONTROLLED TRIAL
Jacqueline A G Sachett, Iran Mendonça da Silva, Eliane Campos Alves, Sâmella S Oliveira, Vanderson S Sampaio, Fábio Francesconi do Vale, Gustavo Adolfo Sierra Romero, Marcelo Cordeiro Dos Santos, Hedylamar Oliveira Marques, Mônica Colombini, Ana Maria Moura da Silva, Fan Hui Wen, Marcus V G Lacerda, Wuelton M Monteiro, Luiz C L Ferreira
BACKGROUND: Secondary bacterial infections from snakebites contribute to the high complication rates that can lead to permanent function loss and disabilities. Although common in endemic areas, routine empirical prophylactic use of antibiotics aiming to prevent secondary infection lacks a clearly defined policy. The aim of this work was to estimate the efficacy of amoxicillin clavulanate for reducing the secondary infection incidence in patients bitten by Bothrops snakes, and, secondarily, identify risk factors for secondary infections from snakebites in the Western Brazilian Amazon...
July 2017: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/28688792/risk-factors-for-transcervical-incision-and-drainage-of-pediatric-deep-neck-infections
#19
Young-Min Hah, Ah Ra Jung, Young Chan Lee, Young-Gyu Eun
OBJECTIVES: The aim of this study was to identify risk factors for transcervical approaches in the treatment of pediatric deep neck infections (DNIs). METHODS: We performed a retrospective analysis of data from patients who were diagnosed with DNIs. All medical records were reviewed for demographic characteristics, presenting signs and symptoms, duration of symptoms, size of abscess, laboratory results, duration of intravenous (IV) antibiotic administration, duration of hospitalization, medical treatment, and type of surgical drainage (oral or transcervical approach)...
June 27, 2017: Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/28671491/seroprevalences-of-feline-leukemia-virus-and-feline-immunodeficiency-virus-infection-in-cats-in-the-united-states-and-canada-and-risk-factors-for-seropositivity
#20
Amie N Burling, Julie K Levy, H Morgan Scott, Michael M Crandall, Sylvia J Tucker, Erin G Wood, Jessie D Foster
OBJECTIVE To estimate seroprevalences for FeLV antigen and anti-FIV antibody and risk factors for seropositivity among cats in the United States and Canada. DESIGN Cross-sectional study. ANIMALS 62,301 cats tested at 1,396 veterinary clinics (n = 45,406) and 127 animal shelters (16,895). PROCEDURES Blood samples were tested with a point-of-care ELISA for FeLV antigen and anti-FIV antibody. Seroprevalence was estimated, and risk factors for seropositivity were evaluated with bivariate and multivariable mixed-model logistic regression analyses adjusted for within-clinic or within-shelter dependencies...
July 15, 2017: Journal of the American Veterinary Medical Association
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