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polypharmacy and elderly

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https://www.readbyqxmd.com/read/28202383/a-randomized-controlled-trial-of-screening-risk-modification-and-physical-therapy-to-prevent-falls-among-the-elderly-recently-discharged-from-the-emergency-department-to-the-community-the-steps-to-avoid-falls-in-the-elderly-study
#1
David B Matchar, Pamela W Duncan, Christopher T C Lien, Marcus Eng Hock Ong, Mina Lee, Fei Gao, Rita Sim, Kirsten Eom
OBJECTIVE: To evaluate the effectiveness of a multifactorial, tailored program of physical therapy to reduce the occurrence of falls among a heterogeneous group of high-risk elderly Singaporeans recently discharged from the Emergency Department (ED). DESIGN: Randomized controlled trial. SETTING: Communities in Central and East regions in Singapore. PARTICIPANTS: 354 adults aged at least 65 years who were seen at ED for a fall or fall-related injuries and discharged home...
February 12, 2017: Archives of Physical Medicine and Rehabilitation
https://www.readbyqxmd.com/read/28184303/deprescribing-medicines-in-the-acute-setting-to-reduce-the-risk-of-falls
#2
Vanessa Marvin, Emily Ward, Alan J Poots, Katie Heard, Arvind Rajagopalan, Barry Jubraj
BACKGROUND: Falls are a common cause of morbidity and hospitalisation in older people. Inappropriate prescribing and polypharmacy contribute to falls risk in elderly patients. This study's aim was to quantify the problem and find out if medication review in the hospital setting led to deprescribing of medicines associated with falls risk. METHODS: Admissions records for elderly patients were examined to identify those whose presenting complaint included a fall. Inpatient medication charts, pharmaceutical care notes, medical notes and discharge summaries were examined to identify any falls-risk medicines from admission histories and to determine if any medication review took place, and whether or not changes were made as a result...
January 2017: European Journal of Hospital Pharmacy. Science and Practice
https://www.readbyqxmd.com/read/28155237/the-use-of-potentially-inappropriate-medications-among-the-lithuanian-elderly-according-to-beers-and-eu-7-pim-list-a-nationwide-cross-sectional-study-on-reimbursement-claims-data
#3
D Grina, V Briedis
WHAT IS KNOWN AND OBJECTIVE: The prevalence and risk factors for prescribing and using potentially inappropriate medications (PIMs) has been extensively researched in Western Europe and the United States of America; however, research in Central and Eastern Europe remains highly limited. According to a recent systematic review, the overall estimated weighted prevalence of PIM prescribing in community-dwelling elderly in Europe (expressed as a percentage of patients or prescriptions with ≥1 PIM) was 22·6% (95% CI: 19·5%-26·7%)...
February 2, 2017: Journal of Clinical Pharmacy and Therapeutics
https://www.readbyqxmd.com/read/28150170/-duodenal-ulcers-gastric-ulcers-and-helicobacter-pylori
#4
Peter Dovjak
The mortality in elderly patients over the age of 80 years with peptic ulcers in the case of complications, such as bleeding and perforation is higher than in the general population. Duodenal ulcers are associated with Helicobacter pylori infections in 90% of cases and in 70% of gastric ulcers. The treatment of elderly patients is often difficult due to multimorbidity and polypharmacy and necessitates a geriatric approach. Ulcers are often caused by medication with nonsteroidal anti-inflammatory drugs (NSAIDs) and acetylsalicylic acid...
February 2017: Zeitschrift Für Gerontologie und Geriatrie
https://www.readbyqxmd.com/read/28144194/the-effects-of-a-web-application-and-medical-monitoring-on-the-quality-of-medication-adverse-drug-events-and-adherence-in-the-elderly-living-at-home-a-protocol-of-the-study
#5
Polona Selic, Eva Cedilnik Gorup, Savin Gorup, Marija Petek Ster, Janez Rifel, Zalika Klemenc Ketis
BACKGROUND: In more than half of elderly chronically-ill family clinic attendees, drug prescribing deviates from the internationally acknowledged STOPP/START recommendations. Our study will determine whether it is possible to improve the quality of drug prescriptions in chronically-ill elderly people living at home by regularly monitoring the prescribed drugs according to STOPP/START criteria. METHODS: The project started in 2014 and will run until 2017. Forty general practitioners (GPs) are participating in a pragmatic randomized controlled trial...
December 2016: Materia Socio-medica
https://www.readbyqxmd.com/read/28141603/prevention-and-management-of-postoperative-delirium-in-elderly-patients-following-elective-spinal-surgery
#6
Alireza K Nazemi, Anirudh K Gowd, Jonathan J Carmouche, Stephen L Kates, Todd J Albert, Caleb J Behrend
STUDY DESIGN: This study is a systematic review. OBJECTIVE: Propose an evidence-based algorithm for prevention, diagnosis, and management of postoperative delirium in geriatric patients undergoing elective spine surgery. SUMMARY OF BACKGROUND DATA: Delirium is associated with longer stays after elective surgery, increased risk of readmission, and $6.9 billion annually in medical costs. Early diagnosis and treatment of delirium can reduce length of stay (LOS), in-hospital morbidity, and health care costs...
January 30, 2017: Clinical Spine Surgery
https://www.readbyqxmd.com/read/28120284/prevalence-of-fecal-incontinence-and-associated-risk-factors-in-elderly-outpatients-a-cross-sectional-study
#7
Nurhan Demir, Mehmet Yuruyen, Kadri Atay, Hakan Yavuzer, Ibrahim Hatemi, Alper Doventas, Deniz Suna Erdincler, Ahmet Dobrucalı
BACKGROUND: Data on the prevalence of fecal incontinence in elderly patients admitted to outpatient clinics in Turkey are scarce. AIMS: The aim of this study was to assess the prevalence of fecal incontinence and the associated risk factors in the elderly outpatients. METHODS: Patients 60 years and older admitted to a geriatrics outpatient clinic between October 2013 and March 2014 were included. Demographic characteristics, anthropometric measurements, marital status, educational status, parity (for females), fecal incontinence (FI), urinary incontinence (UI), constipation, comorbid conditions, and medications were recorded...
January 24, 2017: Aging Clinical and Experimental Research
https://www.readbyqxmd.com/read/28112779/successful-aging-a-new-challenge-for-developing-countries-the-coyoac%C3%A3-n-cohort
#8
J M A García-Lara, A P Navarrete-Reyes, R Medina-Méndez, S G Aguilar-Navarro, J A Avila-Funes
OBJECTIVE: To determine the socio-demographic and health factors associated with a biomedical phenotype of successful aging (SA) among Mexican community-dwelling elderly. DESIGN, SETTING AND PARTICIPANTS: Cross-sectional study of 935 older adults aged 70 or older participating in the Mexican Study of Nutritional and Psychosocial Markers of Frailty. MEASUREMENTS: SA was operationalized in accordance with the phenotype proposed by Rowe and Kahn...
2017: Journal of Nutrition, Health & Aging
https://www.readbyqxmd.com/read/28095959/general-aviation-pilots-over-70-years-old
#9
Alpo Vuorio, Saryani Asmayawati, Bruce Budowle, Robin Griffiths, Timo Strandberg, Jaana Kuoppala, Antti Sajantila
BACKGROUND: Currently it is not unusual for general aviation pilots in the United States to continue to fly beyond the age of 70, even into their 80s and 90s. Pilots have regular examinations according to protocols which do not specify special or additional requirements for pilots over 70 yr of age. Additionally, the third class medical reforms passed by the U.S. Senate on 15 July 2016 could potentially result in even less stringent medical certification requirements for general aviation pilots...
February 1, 2017: Aerospace Medicine and Human Performance
https://www.readbyqxmd.com/read/28095780/effectiveness-of-medication-review-a-systematic-review-and-meta-analysis-of-randomized-controlled-trials
#10
Victor Johan Bernard Huiskes, David Marinus Burger, Cornelia Helena Maria van den Ende, Bartholomeus Johannes Fredericus van den Bemt
BACKGROUND: Medication review is often recommended to optimize medication use. In clinical practice it is mostly operationalized as an intervention without co-interventions during a short term intervention period. However, most systematic reviews also included co-interventions and prolonged medication optimization interventions. Furthermore, most systematic reviews focused on specific patient groups (e.g. polypharmacy, elderly, hospitalized) and/or on specific outcome measures (e.g. hospital admissions and mortality)...
January 17, 2017: BMC Family Practice
https://www.readbyqxmd.com/read/28088178/health-related-quality-of-life-and-associated-factors-in-functionally-independent-older-people
#11
Mónica Machón, Isabel Larrañaga, Miren Dorronsoro, Kalliopi Vrotsou, Itziar Vergara
BACKGROUND: Health-related quality of life (HRQL) is a key indicator of elderly people's health status that can be affected by different factors. However, little is known about which variables are associated with it in functionally independent elderly people. The aim of this project was to study HRQL and a wide variety of health, lifestyle, social and contextual aspects and their relation to HRQL in a sample of functionally independent, non-cognitively impaired community-dwelling adults, over 65 years of age, from a northern region of Spain...
January 14, 2017: BMC Geriatrics
https://www.readbyqxmd.com/read/28056068/the-association-between-polypharmacy-and-dementia-a-nested-case-control-study-based-on-a-12-year-longitudinal-cohort-database-in-south-korea
#12
Hae-Young Park, Ji-Won Park, Hong Ji Song, Hyun Soon Sohn, Jin-Won Kwon
Dementia is a major concern among growing chronic diseases in the aging society and its association with polypharmacy has not been adequately assessed. The objective of this study was to determine the association between polypharmacy and dementia through multiple statistical approaches. We conducted a nested case-control study for newly diagnosed dementia cases using the South Korean National Health Insurance Service sample cohort database (2002-2013, n = 1,025,340). Interactions between polypharmacy (an average use of ≥5 prescription drugs daily) and comorbidities or potentially inappropriate medications (PIMs) were tested...
2017: PloS One
https://www.readbyqxmd.com/read/27974957/prevalence-and-covariates-of-polypharmacy-in-elderly-patients-on-discharge-from-a-tertiary-%C3%A2-care-hospital-in-oman
#13
Amna Al-Hashar, Hamed Al Sinawi, Anwar Al Mahrizi, Manal Al-Hatrushi
OBJECTIVES: To evaluate the prevalence of polypharmacy in relation to gender, comorbidity, and age among elderly patients upon discharge from an academic tertiary care hospital in Muscat, Oman. METHODS: This cross-sectional study was conducted at Sultan Qaboos University Hospital between February and July 2014. We reviewed the electronic medical records of elderly patients aged ≥ 60 years who were admitted to any of the hospital's medical wards during the study period and collected data on age, gender, and diagnoses...
November 2016: Oman Medical Journal
https://www.readbyqxmd.com/read/27972252/polypharmacy-and-medication-adherence-in-elderly-patients-with-diabetes-in-pafos-general-hospital-cyprus
#14
M Geitona, D Latsou, A Georgiou, N Panayidis
No abstract text is available yet for this article.
November 2016: Value in Health: the Journal of the International Society for Pharmacoeconomics and Outcomes Research
https://www.readbyqxmd.com/read/27970989/exploring-determinants-of-polypharmacy-in-the-elderly-population-in-austria
#15
S Mayer, S Vogler, J Simon, A Österle
No abstract text is available yet for this article.
November 2016: Value in Health: the Journal of the International Society for Pharmacoeconomics and Outcomes Research
https://www.readbyqxmd.com/read/27935151/patient-related-characteristics-associated-with-non-persistence-with-statin-therapy-in-elderly-patients-following-an-ischemic-stroke
#16
Martin Wawruch, Dusan Zatko, Gejza Wimmer, Jan Luha, Vasil Hricak, Jan Murin, Peter Kukumberg, Tomas Tesar, Adam Hloska, Rashmi Shah
PURPOSE: This study was aimed at evaluating the extent of non-persistence with statin therapy in elderly patients after an ischemic stroke and identifying patient-related characteristics that are risk factors for non-persistence. METHODS: The evaluable study cohort (n = 2748) was derived from the database of the largest health insurance provider in the Slovak Republic. Patients aged ≥65 years who were initiated on statin therapy following the diagnosis of an ischemic stroke during one full year (1 January 2010 to 31 December 2010) constituted this cohort...
December 9, 2016: Pharmacoepidemiology and Drug Safety
https://www.readbyqxmd.com/read/27932208/a-novel-approach-to-deprescribing-in-long-term-care-settings-the-smart-campaign
#17
Kathleen Abrahamson, Arif Nazir, Karis Pressler
There have been numerous calls within the medical community urging providers to consider the complex problem of inappropriate polypharmacy and inappropriate medication use among nursing home residents. It is clear that innovative, longitudinal policy-supported interventions are needed to better understand prescribing practices in long-term care settings and to curtail the negative, cascading outcomes associated with inappropriate polypharmacy among elderly patients. The Indiana Safer Medication Administration Regimens and Treatment (SMART) campaign is funded by the Indiana State Department of Health for a pilot period of 2 years (2016-18) with the objectives of: 1...
November 30, 2016: Research in Social & Administrative Pharmacy: RSAP
https://www.readbyqxmd.com/read/27924735/-clinical-medication-reviews-in-elderly-patients-with-polypharmacy-a-cross-sectional-study-in-dutch-community-pharmacies
#18
S H Chau, A P D Jansen, P M van de Ven, P Hoogland, P J M Elders, J G Hugtenburg
OBJECTIVE: To investigate the nature and prevalence of drug related problems (DRPs) in older patients with polypharmacy identified by community pharmacists in daily practice through means of a clinical medication review (CMR) and assess the implementation rate of proposed interventions to solve DRPs. DESIGN: A cross-sectional study METHOD: We analysed the CMR data of 3,807 older patients (≥ 65 years) with polypharmacy (≥ 5 drugs) completed in January-August 2012...
2016: Nederlands Tijdschrift Voor Geneeskunde
https://www.readbyqxmd.com/read/27920399/anticoagulation-for-stroke-prevention-in-elderly-patients-with-non-valvular-atrial-fibrillation-what-are-the-obstacles
#19
C W Wong
The elderly with atrial fibrillation are more prone to stroke. Oral anticoagulants such as warfarin are effective in the prevention of atrial fibrillation-associated stroke and systemic embolism. The CHADS2 or CHA2D2-VASc score and HAS-BLED score were developed to stratify stroke risk associated with atrial fibrillation and bleeding risk in a patient with atrial fibrillation, respectively, to facilitate the decision for and safe use of oral anticoagulant. Nonetheless, the decision for anticoagulation is not straightforward and the elderly with non-valvular atrial fibrillation are often precluded from anticoagulant prescription...
December 2016: Hong Kong Medical Journal, Xianggang Yi Xue za Zhi
https://www.readbyqxmd.com/read/27920120/effects-of-an-intervention-s%C3%A3-kl%C3%A3-k-on-prescription-of-potentially-inappropriate-medication-in-elderly-patients
#20
Cecilia Lenander, Åsa Bondesson, Nina Viberg, Ulf Jakobsson, Anders Beckman, Patrik Midlöv
BACKGROUND: Polypharmacy is known to increase the risk for drug-related problems, and some drugs, potentially inappropriate medications (PIMs), are especially troublesome. OBJECTIVE: To analyse the effects on prescription of PIMs of the SÄKLÄK project, an intervention model created to improve medication safety for elderly patients in primary care. METHOD: The SÄKLÄK project was a multiprofessional intervention in primary care consisting of self-assessment, peer review, feedback and written agreements for change...
December 5, 2016: Family Practice
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