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https://www.readbyqxmd.com/read/28821193/therapeutic-plasma-exchange-and-its-impact-on-drug-levels-an-aclps-critical-review
#1
Caleb W Cheng, Jeanne E Hendrickson, Christopher A Tormey, Davinder Sidhu
Objectives: To examine and summarize the current literature on the effects of therapeutic plasma exchange on medication levels. Methods: Literature review was performed via searches of the Cochrane Database and PubMed-MEDLINE (1996 to August 2016) looking for all case reports, case series, and human randomized controlled trials involving therapeutic plasma exchange (TPE)-associated drug removal. Results: Approximately 60 peer-reviewed articles were identified with the majority being case reports; no randomized controlled trials were identified...
September 1, 2017: American Journal of Clinical Pathology
https://www.readbyqxmd.com/read/28821189/y-chromosome-markers-for-the-red-fox
#2
Halie M Rando, Jeremy T Stutchman, Estelle R Bastounes, Jennifer L Johnson, Carlos A Driscoll, Christina S Barr, Lyudmila N Trut, Benjamin N Sacks, Anna V Kukekova
The de novo assembly of the red fox (Vulpes vulpes) genome has facilitated the development of genomic tools for the species. Efforts to identify the population history of red foxes in North America have previously been limited by a lack of information about the red fox Y-chromosome sequence. However, a megabase of red fox Y-chromosome sequence was recently identified over 2 scaffolds in the reference genome. Here, these scaffolds were scanned for repeated motifs, revealing 194 likely microsatellites. Twenty-three of these loci were selected for primer development and, after testing, produced a panel of 11 novel markers that were analyzed alongside 2 markers previously developed for the red fox from dog Y-chromosome sequence...
September 1, 2017: Journal of Heredity
https://www.readbyqxmd.com/read/28821187/genetic-dissection-of-seedling-stage-salinity-tolerance-in-rice-using-introgression-lines-of-a-salt-tolerant-landrace-nona-bokra
#3
Venkata Ramana Rao Puram, John Ontoy, Steven Linscombe, Prasanta K Subudhi
Salinity is an important abiotic stress affecting rice production worldwide. Development of salt tolerant varieties is the most feasible approach for improving rice productivity in salt affected soils. In rice, seedling stage salinity tolerance is crucial for better crop establishment. Quantitative trait loci (QTL) mapping using introgression lines (ILs) is useful for identification and simultaneous transfer of desirable alleles into elite genetic background. In the present study, 138 ILs derived from the cross between a high yielding elite salt susceptible japonica rice cultivar Jupiter and a salt tolerant indica landrace Nona Bokra were evaluated for salt tolerance at seedling stage in a hydroponics experiment and were genotyped using 126 simple sequence repeat markers...
September 1, 2017: Journal of Heredity
https://www.readbyqxmd.com/read/28821165/mirna-21-has-effects-to-protect-kidney-injury-induced-by-sepsis
#4
Dian Fu, Jie Dong, Ping Li, Chaopeng Tang, Wen Cheng, Zhenyu Xu, Wenquan Zhou, Jingping Ge, Chen Xia, Zhengyu Zhang
To investigate the miRNA-21 over-expression in the acute kidney injury induced by sepsis, we developed a sepsis induced in vitro model by lip polysaccharide (LPS) and in vovo model by cecal ligation and puncture (CLP) surgery. LPS or CLP surgery induced kidney cell apoptosis increasing. However, the kidney injury indexes of miRNA groups which were transfected with miRNA-21 were significantly suppressed. In further study, the relative proteins expressions were evaluated to explain the miRNA-21 mechanism to improve sepsis induced kidney cell apoptosis...
August 14, 2017: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/28821153/combination-of-microsized-mineral-particles-and-rosin-as-a-basis-for-converting-cellulosic-fibers-into-sticky-superhydrophobic-paper
#5
Xiaoyan Yu, Peiwen Bian, Yang Xue, Xueren Qian, Haipeng Yu, Wenshuai Chen, Xiaohai Hu, Peng Wang, Dong Wu, Qinghui Duan, Limei Li, Jing Shen, Yonghao Ni
The unique features of cellulosic paper including flexibility, biodegradability, and low cost enables it as a versatile, sustainable biomaterial for promising applications. In the paper industry, microsized mineral particles are widely used in the production of printing/writing paper grades, while rosin derived from trees is the earliest internal sizing agent for paper hydrophobication. On the basis of existing commercial practices associated with the use of mineral particles and rosin in paper production, we present a process concept of converting cellulosic fibers (paper-grade pulp) into "sticky" superhydrophobic paper involving the use of microsized mineral particles and rosin (a tree-derived natural product, mainly a mixture of resin acids, especially abietic acid with chemical formula of C19H29COOH)...
October 15, 2017: Carbohydrate Polymers
https://www.readbyqxmd.com/read/28821147/uv-crosslinkable-and-thermo-responsive-chitosan-hybrid-hydrogel-for-nir-triggered-localized-on-demand-drug-delivery
#6
Lei Wang, Baoqiang Li, Feng Xu, Zheheng Xu, Daqing Wei, Yujie Feng, Yaming Wang, Dechang Jia, Yu Zhou
Innovative drug delivery technologies based on smart hydrogels for localized on-demand drug delivery had aroused great interest. To acquire smart UV-crosslinkable chitosan hydrogel for NIR-triggered localized on-demanded drug release, a novel UV-crosslinkable and thermo-responsive chitosan was first designed and synthesized by grafting with poly N-isopropylacrylamide, acetylation of methacryloyl groups and embedding with photothermal carbon. The UV-crosslinkable unit (methacryloyl groups) endowed chitosan with gelation via UV irradiation...
October 15, 2017: Carbohydrate Polymers
https://www.readbyqxmd.com/read/28821138/biocompatible-chitin-carbon-nanotubes-composite-hydrogels-as-neuronal-growth-substrates
#7
Shuangquan Wu, Bo Duan, Ang Lu, Yanfeng Wang, Qifa Ye, Lina Zhang
In the past decades, extensive studies have demonstrated that carbon nanotubes (CNTs) could promote cell adhesion, proliferation and differentiation of neuronal cells. However, the potential cytotoxicity in biological systems severely restricted the utilization of CNTs as substrates for neural growth. In this study, biocompatible chitin/carbon nanotubes (Ch/CNT) composite hydrogels were developed via blending modified CNTs with chitin solution in 11wt% NaOH/4wt% urea aqueous system, and subsequently regenerating in ethanol...
October 15, 2017: Carbohydrate Polymers
https://www.readbyqxmd.com/read/28821136/discovery-of-enzymatically-depolymerized-heparins-capable-of-treating-bleomycin-induced-pulmonary-injury-and-fibrosis-in-mice
#8
Yishu Yan, Shanshan Du, Yang Ji, Nan Su, Yi Wang, Xiang Mei, Wenming Zhu, Dong He, Yuan Lu, Chong Zhang, Xin-Hui Xing
Heparin has recently been shown to slow down idiopathic pulmonary fibrosis (IPF) process and improve survival of patients in some cases. To improve the anti-IPF function while minimizing their side effects, we developed heparin libraries with different structures depolymerized by single or combined heparinases, and systematically screened the efficacy of the different heparins for treatment of Bleomycin-induced pulmonary injury and fibrosis using mice model. Then we characterized the structural properties of the components capable of treating pulmonary injury and fibrosis by use of chip-based amide hydrophilic interaction chromatography (HILIC)-fourier transform (FT)-ESI-MS, polyacrylamide gel electrophoresis (PAGE), and high performance liquid chromatography (HPLC)...
October 15, 2017: Carbohydrate Polymers
https://www.readbyqxmd.com/read/28821128/biomimetic-composite-scaffolds-based-on-surface-modification-of-polydopamine-on-electrospun-poly-lactic-acid-cellulose-nanofibrils
#9
Zhangqiang Yang, Junhui Si, Zhixiang Cui, Jianhua Ye, Xiaofeng Wang, Qianting Wang, Kaiping Peng, Wenzhe Chen, Shia-Chung Chen
An appropriate surface chemical property is crucial in tissue engineering scaffolds, which promotes cell attachment and proliferation. A biomimetic composite scaffold with a polydopamine (PDA) coating layer on electrospun poly(lactic acid) (PLA)/cellulose nanofibrils (CNF) composite nanofiber was developed in this study. PLA/CNF composite nanofibers were fabricated and then coated via treatment with a dopamine solution. The PDA coating layer was successfully formed on the surface of the PLA/CNF composite nanofiber by using a simple, environment-friendly, and effective procedure...
October 15, 2017: Carbohydrate Polymers
https://www.readbyqxmd.com/read/28821122/-click-hyaluronan-based-nanohydrogels-as-multifunctionalizable-carriers-for-hydrophobic-drugs
#10
Giuliana Manzi, Nicole Zoratto, Silvia Matano, Rocchina Sabia, Claudio Villani, Tommasina Coviello, Pietro Matricardi, Chiara Di Meo
Highly hydrophilic and biocompatible nanocarriers based on polysaccharide hydrogels (nanohydrogels, NHs) were shown to be promising systems for drug delivery applications. Following the idea of these emerging drug carriers, the aim of the present work was to develop self-assembled hydrogel nanoparticles based on amphiphilic derivatives of hyaluronic acid (HA) and riboflavin (Rfv), synthesized by "click" Copper(I)-catalyzed Azide-Alkyne Cycloaddition (CuAAC) reaction. The obtained amphiphilic product (HA-c-Rfv) was able to form nanohydrogels in aqueous environments, in particular by applying an innovative autoclave-based method...
October 15, 2017: Carbohydrate Polymers
https://www.readbyqxmd.com/read/28821111/a-facile-sodium-alginate-based-approach-to-improve-the-mechanical-properties-of-recycled-fibers
#11
Yuan-Yuan Bai, Yan-Hao Lei, Xiao-Jun Shen, Jing Luo, Chun-Li Yao, Run-Cang Sun
The application of recycled fibers is steadily increasing in various paper products recently. It is necessary to improve the mechanical properties of paper products made from these fibers. An eco-friendly polymeric additive, sodium alginate (SA), was prepared from waste seaweeds and developed as functional additives. The properties of SA were characterized by proton nuclear magnetic resonance, Fourier transform infrared spectroscopy, thermal gravity analysis, gel permeation chromatography, and compared with the commercial SA...
October 15, 2017: Carbohydrate Polymers
https://www.readbyqxmd.com/read/28821101/cholesteric-film-of-cu-ii-doped-cellulose-nanocrystals-for-colorimetric-sensing-of-ammonia-gas
#12
Shidong Dai, Nana Prempeh, Dagang Liu, Yimin Fan, Mingyue Gu, Yu Chang
With the increasing demand of environmental monitoring for toxic and odorous ammonia gas it is desired to develop specific green, cost-effective and in situ passive colorimetric alternatives to current complex instrumentations. In this work, we designed an ammonia gas sensor based on cholesteric liquid crystal films of copper(II)-doped cellulose nanocrystals (CNCCu(II)) whose structure, optical and sensing properties were investigated. The hybrid films using the low doping Cu(II) as a color-tuning agent inherited the chiral nematic signature and optical activity of CNCs, suggesting a strong chelation between copper ions and negatively charged CNCs...
October 15, 2017: Carbohydrate Polymers
https://www.readbyqxmd.com/read/28821098/physical-chemical-characteristics-and-potential-use-of-a-novel-alginate-zein-hydrogel-as-the-sorption-phase-for-polar-organic-compounds
#13
Natara D B Castilhos, Naiara M F M Sampaio, Bruno C da Silva, Izabel C Riegel-Vidotti, Marco T Grassi, Bruno J G Silva
A novel alginate based hydrogel was successfully prepared and tested for the solid phase microextraction of medium-to-high polarity compounds, when supported in a polypropylene (PP) fiber. Pure alginate when added onto the surface of the PP fiber, resulted in a significant improvement in the extraction efficiency of the analytes (except for β-estradiol). The alginate hydrogel was modified upon the incorporation of a small amount of zein, a corn protein. Interestingly, the alginate/zein-supported hydrogel was capable of successfully extracting compounds with low partition constant (Kow), such as 17-α-ethinyl estradiol, progesterone and estriol, since the initial water uptake decreased dramatically in this gel, therefore, leaving the alginate hydroxyl groups more available to interact with the polar compounds...
October 15, 2017: Carbohydrate Polymers
https://www.readbyqxmd.com/read/28821094/decoration-of-open-pore-network-in-polyvinylidene-fluoride-mwcnts-with-chitosan-for-the-removal-of-reactive-orange-16-dye
#14
Maria Wasim, Sadia Sagar, Aneela Sabir, Muhammad Shafiq, Tahir Jamil
Inspired by the hydrophilic, biocompatible, adsorbent properties of chitosan. A simple, adaptable, green synthesis method was developed to prepare a thin film composite membranes using chitosan as a pore decorating material for the removal of anionic dye-Reactive orange 16 (RO-16). The hydrophilic chitosan was used to fill up the porous hydrophobic PVDF substrate, modified by MWCNTs. The dye rejection was carried out through the formation of a strong electrostatic interaction between the cationic group of chitosan surface and the anionic group of RO-16 dye...
October 15, 2017: Carbohydrate Polymers
https://www.readbyqxmd.com/read/28821079/highly-monodisperse-colloidal-coacervates-based-on-a-bioactive-lactose-modified-chitosan-from-synthesis-to-characterization
#15
Franco Furlani, Pasquale Sacco, Eleonora Marsich, Ivan Donati, Sergio Paoletti
The present contribution aims at describing the fabrication of coacervates in the nano-size range starting from a 1-deoxylactit-1-yl chitosan (in this manuscript termed as CTL60) and the multivalent anion tripolyphosphate (TPP). Colloidal coacervates have been obtained for precise values of the molar ratio of TPP to CTL60 repeating unit. Coacervation is ensured only at pH 4.5 and not at 7.4, thus demonstrating the key role of electrostatic interactions in the stabilization of the coacervates. At a variance with chitosan, CTL60 favors the formation of highly homogeneous coacervates with very low values of the polydispersity index (PDI)...
October 15, 2017: Carbohydrate Polymers
https://www.readbyqxmd.com/read/28821071/on-the-use-of-ion-crosslinked-nanocellulose-hydrogels-for-wound-healing-solutions-physicochemical-properties-and-application-oriented-biocompatibility-studies
#16
Alex Basu, Jonas Lindh, Eva Ålander, Maria Strømme, Natalia Ferraz
Calcium ion-crosslinked nanofibrillated cellulose (NFC) hydrogels were investigated as potential materials for wound healing dressings. The physicochemical properties of the hydrogels were examined by rheology and water retention tests. Skin cells and monocytes were selected for application-oriented biocompatibility studies. The NFC hydrogels presented entangled fibrous networks and solid-like behavior. Water retention tests showed the material´s potential to maintain a suitable moist environment for different type of wounds...
October 15, 2017: Carbohydrate Polymers
https://www.readbyqxmd.com/read/28821063/development-and-characterization-of-banana-flour-film-incorporated-with-montmorillonite-and-banana-starch-nanoparticles
#17
Aungkana Orsuwan, Rungsinee Sothornvit
Banana flour film is an alternative biopolymer material but still needs improvement of its mechanical properties and water vapor permeability. Banana starch nanoparticles (BSNs), prepared using miniemulsion cross-linking, make an interesting reinforcing agent. The properties of plasticized banana flour film (PBF) were characterized incorporated with 5% (w/w) of either montmorillonite; MMT-Na(+) (PBF-M) or BSN (PBF-B), including a mixture of nanoparticles at 1:1 for 5% (PBF-MB5) and 10% (PBF-MB10). PBF-MB5 provided better improvement in the film mechanical and water barrier properties compared with PBF-B...
October 15, 2017: Carbohydrate Polymers
https://www.readbyqxmd.com/read/28821060/construction-and-characterization-of-nanosized-curdlan-sulfate-chitosan-polyelectrolyte-complex-toward-drug-release-of-zidovudine
#18
Jing-Kun Yan, Yao-Yao Wang, Wen-Yi Qiu, Jian-Yong Wu
In this study, as-synthesized curdlan sulfate (CRDS) with a flexible random coil chain was selected as a polyanion to construct nanosized polyelectrolyte complexes (PECs) with a polycation, chitosan (CS), via electrostatic interactions. Nanosized PECs were formed simply by mixing CRDS (0.5mg/mL) and CS (0.5mg/mL) at a mass ratio of 2:1 at pH 3.5. The CRDS/CS PECs exhibited a spherical morphology with a Z-average diameter of around 180nm and a zeta potential value of about -38mV. Subsequently, zidovudine (AZT) as a model antiviral drug was successfully encapsulated into the nanosized PECs with a favorable drug loading efficiency...
October 15, 2017: Carbohydrate Polymers
https://www.readbyqxmd.com/read/28821055/improvement-of-silicate-cement-properties-with-bacterial-cellulose-powder-addition-for-applications-in-dentistry
#19
Georgeta Voicu, Sorin-Ion Jinga, Bogdan-Gabriel Drosu, Cristina Busuioc
The goal of this paper was to synthesize a new family of composites starting from mineral binder powders and biocellulose membranes, with applications in endodontics. An important achievement consisted in the crushing of biocellulose 3D structure in a polygranular powder via an hydrothermal treatment. Afterwards, the polymer powder was mixed with silicate cement powders synthesized through the sol-gel technique. The resulting hybrid materials were investigated by thermal analysis, X-ray diffraction, scanning electron microscopy and mechanical measurements...
October 15, 2017: Carbohydrate Polymers
https://www.readbyqxmd.com/read/28821043/effect-of-moderate-electric-fields-in-the-properties-of-starch-and-chitosan-films-reinforced-with-microcrystalline-cellulose
#20
Caroline C S Coelho, Miguel A Cerqueira, Ricardo N Pereira, Lorenzo M Pastrana, Otniel Freitas-Silva, António A Vicente, Lourdes M C Cabral, José A Teixeira
Microcrystalline cellulose (MCC) can provide improved properties when the aim is the development of biodegradable packaging materials. In this work the physicochemical properties of polysaccharide-based films (chitosan and starch) with the incorporation of MCC and the application of moderate electric field (MEF) and ultrasonic bath (UB) as treatments, were evaluated. For each treatment, the thickness, moisture content, solubility, water vapor permeability, contact angle, mechanical properties, along with its color and opacity were determined...
October 15, 2017: Carbohydrate Polymers
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