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https://www.readbyqxmd.com/read/28333492/perceptual-and-memory-inhibition-deficits-in-clinically-healthy-older-adults-are-associated-with-region-specific-doubly-dissociable-patterns-of-cortical-thinning
#1
Teal S Eich, Qolamreza R Razlighi, Yaakov Stern
Converging evidence suggests that the cognitive control processes that enable the inhibition of irrelevant information on a perceptual versus a memorial basis are qualitatively different and are underlain by unique neural systems that may be affected differentially in aging. In the current study, we investigated whether individual differences in performance on these 2 types of inhibitory processes were attributable to region-specific patterns of cortical thinning. Clinically healthy older adults completed a pair of behavioral memory and perceptual inhibition tasks and then underwent structural brain imaging...
March 23, 2017: Behavioral Neuroscience
https://www.readbyqxmd.com/read/28276516/electrochemical-tuning-of-the-optical-properties-of-nanoporous-gold
#2
D Jalas, L-H Shao, R Canchi, T Okuma, S Lang, A Petrov, J Weissmüller, M Eich
Using optical in-situ measurements in an electrochemical environment, we study the electrochemical tuning of the transmission spectrum of films from the nanoporous gold (NPG) based optical metamaterial, including the effect of the ligament size. The long wavelength part of the transmission spectrum around 800 nm can be reversibly tuned via the applied electrode potential. The NPG behaves as diluted metal with its transition from dielectric to metallic response shifted to longer wavelengths. We find that the applied potential alters the charge carrier density to a comparable extent as in experiments on gold nanoparticles...
March 9, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28265509/new-in-vitro-system-to-predict-chemotherapeutic-efficacy-of-drug-combinations-in-fresh-tumor-samples
#3
Frank Christian Kischkel, Julia Eich, Carina I Meyer, Paula Weidemüller, Jens Krapfl, Rauaa Yassin-Kelepir, Laura Job, Marius Fraefel, Ioana Braicu, Annette Kopp-Schneider, Jalid Sehouli, Rudy Leon De Wilde
BACKGROUND: To find the best individual chemotherapy for cancer patients, the efficacy of different chemotherapeutic drugs can be predicted by pretesting tumor samples in vitro via the chemotherapy-resistance (CTR)-Test(®). Although drug combinations are widely used among cancer therapy, so far only single drugs are tested by this and other tests. However, several first line chemotherapies are combining two or more chemotherapeutics, leading to the necessity of drug combination testing methods...
2017: PeerJ
https://www.readbyqxmd.com/read/28236583/progression-free-survival-of-early-interim-pet-positive-patients-with-advanced-stage-hodgkin-s-lymphoma-treated-with-beacoppescalated-alone-or-in-combination-with-rituximab-hd18-an-open-label-international-randomised-phase-3-study-by-the-german-hodgkin-study
#4
Peter Borchmann, Heinz Haverkamp, Andreas Lohri, Ulrich Mey, Stefanie Kreissl, Richard Greil, Jana Markova, Michaela Feuring-Buske, Julia Meissner, Ulrich Dührsen, Helmut Ostermann, Ulrich Keller, Georg Maschmeyer, Georg Kuhnert, Markus Dietlein, Carsten Kobe, Hans Eich, Christian Baues, Harald Stein, Michael Fuchs, Volker Diehl, Andreas Engert
BACKGROUND: Advanced stage Hodgkin's lymphoma represents a heterogeneous group of patients with different risk profiles. Data suggests that interim PET assessment during chemotherapy is superior to baseline international prognostic scoring in terms of predicting long-term treatment outcome in patients with Hodgkin's lymphoma. We therefore hypothesised that early interim PET-imaging after two courses of bleomycin, etoposide, doxorubicin, cyclophosphamide, vincristine, procarbazine, and prednisone (BEACOPP) might be suitable for guiding treatment in patients with advanced stage Hodgkin's lymphoma...
February 21, 2017: Lancet Oncology
https://www.readbyqxmd.com/read/28181470/controlled-release-of-antigen-and-toll-like-receptor-ligands-from-plga-nanoparticles-enhances-immunogenicity
#5
Luis J Cruz, Paul J Tacken, Christina Eich, Felix Rueda, Ruurd Torensma, Carl G Figdor
AIM: Dendritic cells rapidly capture nanoparticles and induce a potent cellular immune response. It is yet unknown whether the immunological response induced by slow release of encapsulated versus soluble antigen and adjuvant is superior. MATERIALS & METHODS: The kinetics of poly(lactic-co-glycolic acid) PLGA nanoparticles antigen release was studied by the DQ-bovine serum albumin (BSA) self-quenching antigen model. The immunological response induced was evaluated by means of dendritic cell activation/maturation markers, cytokine production and their ability to drive antigen-specific T-cell proliferation...
February 9, 2017: Nanomedicine
https://www.readbyqxmd.com/read/28121974/intranasal-analgesia-and-sedation-in-pediatric-emergency-care-a-prospective-observational-study-on-the-implementation-of-an-institutional-protocol-in-a-tertiary-children-s-hospital
#6
Marcus Nemeth, Nils Jacobsen, Carsten Bantel, Melanie Fieler, Robert Sümpelmann, Christoph Eich
OBJECTIVES: Children presenting with acute traumatic pain or in need of therapeutic or diagnostic procedures require rapid and effective analgesia and/or sedation. Intranasal administration (INA) promises to be a reliable, minimally invasive delivery route. However, INA is still underused in Germany. We hence developed a protocol for acute pain therapy (APT) and urgent analgesia and/or sedation (UAS). Our aim was to evaluate the effectiveness and safety of our protocol. METHODS: We performed a prospective observational study in a tertiary children's hospital in Germany...
January 24, 2017: Pediatric Emergency Care
https://www.readbyqxmd.com/read/28093639/the-effectiveness-of-radiotherapy-for-leukemia-cutis
#7
Khaled Elsayad, Michael Oertel, Uwe Haverkamp, Hans Theodor Eich
BACKGROUND: Leukemia cutis (LC) is a rare clinical presentation of leukemia that is associated with poor prognosisabs. To date, the value of radiotherapy (RT) for the treatment of LC remains controversial. Therefore, the aim of this study was to analyse the effectiveness of various RT doses for LC. METHODS AND MATERIALS: Between January 2000 and January 2016, 13 patients underwent RT at our institution after exhibiting progressive disease following other treatment modalities...
January 16, 2017: Journal of Cancer Research and Clinical Oncology
https://www.readbyqxmd.com/read/28091756/-recommendation-on-temperature-management-after-cardiopulmonary-arrest-and-severe-traumatic-brain-injury-in-childhood-beyond-the-neonatal-period-statement-of-the-german-society-for-neonatology-and-pediatric-intensive-care-medicine%C3%A2-gnpi-and-the-scientific-working
#8
S Brenner, C Eich, G Rellensmann, M U Schuhmann, T Nicolai, F Hoffmann
The available data on the effectiveness of therapeutic hypothermia in different patient groups are heterogeneous. Although the benefits have been proven for some collectives, recommendations for the use of hypothermia treatment in other groups are based on less robust data and conclusions by analogy. This article gives a review of the current evidence of temperature management in all age groups and based on this state of knowledge, recommends active temperature management with the primary aim of strict normothermia (36-36...
February 2017: Der Anaesthesist
https://www.readbyqxmd.com/read/27991434/functional-theories-of-thermoelectric-phenomena
#9
F G Eich, M Di Ventra, G Vignale
We review the progress that has been recently made in the application of time-dependent density functional theory to thermoelectric phenomena. As the field is very young, we emphasize open problems and fundamental issues. We begin by introducing the formal structure of thermal density functional theory, a density functional theory with two basic variables-the density and the energy density-and two conjugate fields-the ordinary scalar potential and Luttinger's thermomechanical potential. The static version of this theory is contrasted with the familiar finite-temperature density functional theory, in which only the density is a variable...
February 15, 2017: Journal of Physics. Condensed Matter: An Institute of Physics Journal
https://www.readbyqxmd.com/read/27966192/how-does-a-shared-decision-making-sdm-intervention-for-oncologists-affect-participation-style-and-preference-matching-in-patients-with-breast-and-colon-cancer
#10
Christiane Bieber, Jennifer Nicolai, Kathrin Gschwendtner, Nicole Müller, Katrin Reuter, Angela Buchholz, Birgit Kallinowski, Martin Härter, Wolfgang Eich
The aims of this study are to assess patients' preferred and perceived decision-making roles and preference matching in a sample of German breast and colon cancer patients and to investigate how a shared decision-making (SDM) intervention for oncologists influences patients' preferred and perceived decision-making roles and the attainment of preference matches. This study is a post hoc analysis of a randomised controlled trial (RCT) on the effects of an SDM intervention. The SDM intervention was a 12-h SDM training program for physicians in combination with decision board use...
December 13, 2016: Journal of Cancer Education: the Official Journal of the American Association for Cancer Education
https://www.readbyqxmd.com/read/27957589/radiotherapy-for-aneurysmal-bone-cysts-a%C3%A2-rare-indication
#11
Khaled Elsayad, Jan Kriz, Heinrich Seegenschmiedt, Detlef Imhoff, Reinhard Heyd, Hans Theodor Eich, Oliver Micke
BACKGROUND: Aneurysmal bone cysts (ABC) are rapidly growing benign osseous lesions composed of blood-filled channels separated by fibrous septa. Since the value of external beam radiotherapy (EBRT) for ABC has not been well defined, the German Cooperative Group on Radiotherapy for Benign Diseases performed the national register study described herein. PATIENTS AND METHODS: Five German institutions collected data regarding clinical features, treatment concepts, and outcome for patients with ABC who had been referred for local EBRT over the past 30 years...
April 2017: Strahlentherapie und Onkologie: Organ der Deutschen Röntgengesellschaft ... [et Al]
https://www.readbyqxmd.com/read/27902566/conditioned-pain-modulation-in-patients-with-nonspecific-chronic-back-pain-with-chronic-local-pain-chronic-widespread-pain-and-fibromyalgia
#12
Andreas Gerhardt, Wolfgang Eich, Rolf-Detlef Treede, Jonas Tesarz
Findings considering conditioned pain modulation (CPM) in chronic back pain (CBP) are contradictory. This might be because many patients with CBP report pain in further areas of the body, and altered CPM might influence spatial extent of pain rather than CBP per se. Therefore, we compared CPM in patients with CBP with different pain extent. Patients with fibromyalgia syndrome (FMS), for whom CPM impairment is reported most consistently, were measured for comparison. Based on clinical evaluation and pain drawings, patients were categorized into chronic local back pain (CLP; n = 53), chronic widespread back pain (CWP; n = 32), and FMS (n = 92)...
March 2017: Pain
https://www.readbyqxmd.com/read/27872635/rhizosphere-organic-anions-play-a-minor-role-in-improving-crop-species-ability-to-take-up-residual-phosphorus-p-in-agricultural-soils-low-in-p-availability
#13
Yanliang Wang, Tore Krogstad, Jihong L Clarke, Moritz Hallama, Anne F Øgaard, Susanne Eich-Greatorex, Ellen Kandeler, Nicholas Clarke
Many arable lands have accumulated large reserves of residual phosphorus (P) and a relatively large proportion of soil P is less available for uptake by plants. Root released organic anions are widely documented as a key physiological strategy to enhance P availability, while limited information has been generated on the contribution of rhizosphere organic anions to P utilization by crops grown in agricultural soils that are low in available P and high in extractable Ca, Al, and Fe. We studied the role of rhizosphere organic anions in P uptake from residual P in four common crops Triticum aestivum, Avena sativa, Solanum tuberosum, and Brassica napus in low- and high-P availability agricultural soils from long-term fertilization field trials in a mini-rhizotron experiment with four replications...
2016: Frontiers in Plant Science
https://www.readbyqxmd.com/read/27747968/perioperative-intravenous-fluid-therapy-in-children-guidelines-from-the-association-of-the-scientific-medical-societies-in-germany
#14
Robert Sümpelmann, Karin Becke, Sebastian Brenner, Christian Breschan, Christoph Eich, Claudia Höhne, Martin Jöhr, Franz-Josef Kretz, Gernot Marx, Lars Pape, Markus Schreiber, Jochen Strauss, Markus Weiss
This consensus- based S1 Guideline for perioperative infusion therapy in children is focused on safety and efficacy. The objective is to maintain or re-establish the child's normal physiological state (normovolemia, normal tissue perfusion, normal metabolic function, normal acid- base- electrolyte status). Therefore, the perioperative fasting times should be as short as possible to prevent patient discomfort, dehydration, and ketoacidosis. A physiologically composed balanced isotonic electrolyte solution (BS) with 1-2...
January 2017: Paediatric Anaesthesia
https://www.readbyqxmd.com/read/27698341/self-amplified-photo-induced-gap-quenching-in-a-correlated-electron-material
#15
S Mathias, S Eich, J Urbancic, S Michael, A V Carr, S Emmerich, A Stange, T Popmintchev, T Rohwer, M Wiesenmayer, A Ruffing, S Jakobs, S Hellmann, P Matyba, C Chen, L Kipp, M Bauer, H C Kapteyn, H C Schneider, K Rossnagel, M M Murnane, M Aeschlimann
Capturing the dynamic electronic band structure of a correlated material presents a powerful capability for uncovering the complex couplings between the electronic and structural degrees of freedom. When combined with ultrafast laser excitation, new phases of matter can result, since far-from-equilibrium excited states are instantaneously populated. Here, we elucidate a general relation between ultrafast non-equilibrium electron dynamics and the size of the characteristic energy gap in a correlated electron material...
October 4, 2016: Nature Communications
https://www.readbyqxmd.com/read/27678010/new-quality-assurance-program-integrating-modern-radiotherapy-within-the-german-hodgkin-study-group
#16
J Kriz, C Baues, R Engenhart-Cabillic, U Haverkamp, K Herfarth, P Lukas, H Schmidberger, S Marnitz-Schulze, M Fuchs, A Engert, H T Eich
INTRODUCTION: Field design changed substantially from extended-field RT (EF-RT) to involved-field RT (IF-RT) and now to involved-node RT (IN-RT) and involved-site RT (IS-RT) as well as treatment techniques in radiotherapy (RT) of Hodgkin's lymphoma (HL). The purpose of this article is to demonstrate the establishment of a quality assurance program (QAP) including modern RT techniques and field designs within the German Hodgkin Study Group (GHSG). METHODS: In the era of modern conformal RT, this QAP had to be fundamentally adapted and a new evaluation process has been intensively discussed by the radiotherapeutic expert panel of the GHSG...
February 2017: Strahlentherapie und Onkologie: Organ der Deutschen Röntgengesellschaft ... [et Al]
https://www.readbyqxmd.com/read/27674864/updated-strategies-in-the-treatment-of-benign-diseases-a-patterns-of-care-study-of-the-german-cooperative-group-on-benign-diseases
#17
J Kriz, H Seegenschmiedt, A Bartels, O Micke, R Muecke, U Schaefer, U Haverkamp, H Eich
No abstract text is available yet for this article.
October 1, 2016: International Journal of Radiation Oncology, Biology, Physics
https://www.readbyqxmd.com/read/27674260/a-dosimetric-comparison-between-conventionally-fractionated-tomotherapy-volumetric-modulated-arc-therapy-sliding-window-and-proton-therapy-and-hypofractionated-robotic-radiosurgery-treatment-by-low-risk-prostate-carcinoma
#18
S Scobioala, C Kittel, U Haverkamp, M Channaoui, O Habibeh, K Elsayad, H T T Eich
No abstract text is available yet for this article.
October 1, 2016: International Journal of Radiation Oncology, Biology, Physics
https://www.readbyqxmd.com/read/27671348/a-treatment-planning-study-comparing-tomotherapy-volumetric-modulated-arc-therapy-sliding-window-and-proton-therapy-for-low-risk-prostate-carcinoma
#19
Sergiu Scobioala, Christopher Kittel, Nicolas Wissmann, Uwe Haverkamp, Mohammed Channaoui, Omar Habibeh, Khaled Elsayad, Hans Theodor Eich
BACKGROUND: Comparing radiation treatment plans to ascertain the optimal intensity-modulated radiation technique for low-risk prostate cancer. METHODS: Treatment plans for 20 randomly selected patients were generated using the same dose objectives. A dosimetric comparison was performed between various intensity-modulated techniques, including protons. All treatment plans provided conventional treatment with 79.2Gy. Dosimetric indices for the target volume and organs at risk (OAR), including homogeneity index and four conformity indices were analyzed...
September 27, 2016: Radiation Oncology
https://www.readbyqxmd.com/read/27663691/can-we-foster-a-culture-of-peer-support-and-promote-mental-health-in-adolescence-using-a-web-based-app-a-control-group-study
#20
Laura Bohleber, Aureliano Crameri, Brigitte Eich-Stierli, Rainer Telesko, Agnes von Wyl
BACKGROUND: Adolescence with its many transitions is a vulnerable period for the development of mental illnesses. Establishing effective mental health promotion programs for this age group is a challenge crucial to societal health. Programs must account for the specific developmental tasks that adolescents face. Considering peer influence and fostering adolescent autonomy strivings is essential. Participation in a program should be compelling to young people, and their affinity to new technologies offers unprecedented opportunities in this respect...
September 23, 2016: JMIR Mental Health
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