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https://www.readbyqxmd.com/read/28630331/distinguishing-attosecond-electron-electron-scattering-and-screening-in-transition-metals
#1
Cong Chen, Zhensheng Tao, Adra Carr, Piotr Matyba, Tibor Szilvási, Sebastian Emmerich, Martin Piecuch, Mark Keller, Dmitriy Zusin, Steffen Eich, Markus Rollinger, Wenjing You, Stefan Mathias, Uwe Thumm, Manos Mavrikakis, Martin Aeschlimann, Peter M Oppeneer, Henry Kapteyn, Margaret Murnane
Electron-electron interactions are the fastest processes in materials, occurring on femtosecond to attosecond timescales, depending on the electronic band structure of the material and the excitation energy. Such interactions can play a dominant role in light-induced processes such as nano-enhanced plasmonics and catalysis, light harvesting, or phase transitions. However, to date it has not been possible to experimentally distinguish fundamental electron interactions such as scattering and screening. Here, we use sequences of attosecond pulses to directly measure electron-electron interactions in different bands of different materials with both simple and complex Fermi surfaces...
June 19, 2017: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/28624137/effect-of-tlr-ligands-co-encapsulated-with-multiepitopic-antigen-in-nanoliposomes-targeted-to-human-dcs-via-fc-receptor-for-cancer-vaccines
#2
Felix Rueda, Christina Eich, Begoña Cordobilla, Pere Domingo, Gerardo Acosta, Fernando Albericio, Luis J Cruz, Joan C Domingo
Nanoliposomes (NLs) hold promise as new highly specific nanomedicine for anti-tumor vaccines, since they could be targeted to specific receptors on dendritic cell (DC) to induce maturation and activation and increase the anti-tumor immune response. Here we studied a NLs formulation targeted or not to FcR (the receptor for the IgG Fc fragment) for the treatment of androgen-responsive prostate cancer. Luteinizing-hormone-releasing hormone (LHRH) peptide (B- and T-cell epitopes), in tandem with a tetanus toxoid T-helper epitope (830-844 region) and several TLR (Toll-Like Receptor) ligands as adjuvants were co-encapsulated...
June 10, 2017: Immunobiology
https://www.readbyqxmd.com/read/28599339/-shared-decision-making-sdm-patient-and-physician-as-a-team
#3
C Bieber, K Gschwendtner, N Müller, W Eich
The article provides an overview on Shared Decision Making (SDM), which is considered as the ideal form of physician-patient-interaction by many stakeholders of the health care system. SDM is distinguished from other models of physician-patient-interaction such as the paternalistic model and the information model. Besides the degree of acceptance of SDM in the general population and among physicians, barriers for its implementation will be reported. Indications for SDM as well as strategies and support material for its use in individual consultations will be discussed and illustrated by an oncological case study...
June 2017: Die Rehabilitation
https://www.readbyqxmd.com/read/28597078/spectrum-of-genetic-mutations-in-de-novo-punlmp-of-the-urinary-bladder
#4
Maria Del Carmen Rodriguez Pena, Aline C Tregnago, Marie-Lisa Eich, Simeon Springer, Yuxuan Wang, Diana Taheri, Dilek Ertoy, Kazutoshi Fujita, Stephania M Bezerra, Isabela W Cunha, Maria Rosaria Raspollini, Lijia Yu, Trinity J Bivalacqua, Nickolas Papadopoulos, Kenneth W Kinzler, Bert Vogelstein, George J Netto
Our group and others have previously demonstrated the presence of TERT promoter mutations (TERT-mut) in 60-80% of urothelial carcinomas and some of their histologic variants. Five other genes have been frequently implicated in bladder cancer: FGRF3, TP53, PIK3CA, HRAS, and CDKN2A. In the current study, we sought to determine the prevalence of mutations in TERT and these five other genes in de novo papillary urothelial neoplasms of low malignant potential (PUNLMP) of the urinary bladder. A retrospective search of our archives for PUNLMP was performed and 30 de novo cases were identified and included in the study...
June 8, 2017: Virchows Archiv: An International Journal of Pathology
https://www.readbyqxmd.com/read/28586378/quantification-of-%C3%AE-%C3%AE-t-cells-and-hla-dr-nk-cells-does-not-predict-emergence-of-new-contrast-enhancing-lesions-in-ms-patients-suspending-natalizumab-treatment
#5
Mindaugas Paužuolis, Torsten Eich, Joachim Burman
BACKGROUND: Natalizumab (NTZ) is a drug that has been widely used in the treatment of multiple sclerosis (MS). NTZ is very effective in suppressing inflammation, but if treatment is suspended many patients will experience relapses. OBJECTIVE: To investigate if quantification of γδ T cells and HLA-DR+ NK cells could predict early disease reactivation after NTZ suspension. METHODS: Absolute counts of γδ T cells and HLA-DR+ NK cells in whole blood were determined with flow cytometry in fifteen patients treated with NTZ...
2017: PloS One
https://www.readbyqxmd.com/read/28567503/planning-benchmark-study-for-sbrt-of-early-stage-nsclc-results-of-the-degro-working-group-stereotactic-radiotherapy
#6
Christos Moustakis, Oliver Blanck, Fatemeh Ebrahimi Tazehmahalleh, Mark Ka Heng Chan, Iris Ernst, Thomas Krieger, Marciana-Nona Duma, Markus Oechsner, Ute Ganswindt, Christian Heinz, Horst Alheit, Hilbert Blank, Ursula Nestle, Rolf Wiehle, Christine Kornhuber, Christian Ostheimer, Cordula Petersen, Gerhard Pollul, Wolfgang Baus, Georg Altenstein, Eric Beckers, Katrin Jurianz, Florian Sterzing, Matthias Kretschmer, Heinrich Seegenschmiedt, Torsten Maass, Stefan Droege, Ulrich Wolf, Juergen Schoeffler, Uwe Haverkamp, Hans Theodor Eich, Matthias Guckenberger
PURPOSE: The aim was to evaluate stereotactic body radiation therapy (SBRT) treatment planning variability for early stage nonsmall cell lung cancer (NSCLC) with respect to the published guidelines of the Stereotactic Radiotherapy Working Group of the German Society for Radiation Oncology (DEGRO). MATERIALS AND METHODS: Planning computed tomography (CT) scan and the structure sets (planning target volume, PTV; organs at risk, OARs) of 3 patients with early stage NSCLC were sent to 22 radiotherapy departments with SBRT experience: each department was asked to prepare a treatment plan according to the DEGRO guidelines...
May 31, 2017: Strahlentherapie und Onkologie: Organ der Deutschen Röntgengesellschaft ... [et Al]
https://www.readbyqxmd.com/read/28546055/the-long-way-of-implementing-patient-centered-care-and-shared-decision-making-in-germany
#7
Martin Härter, Jörg Dirmaier, Isabelle Scholl, Norbert Donner-Banzhoff, Marie-Luise Dierks, Wolfgang Eich, Hardy Müller, David Klemperer, Klaus Koch, Christiane Bieber
The main focus of the paper is on the description of the development and current state of research and implementation of patient-centered care (PCC) and shared decision-making (SDM) after fifteen years of substantial advances in health policy and health services research. What is the current state of SDM in health policy? The "Law on Patients' Rights" from 2013 standardizes all rights and responsibilities within the framework of medical treatment for German citizens and legal residents. This comprises the right to informed decisions, comprehensive and comprehensible information for patients, and decisions based on a clinician-patient-partnership...
May 22, 2017: Zeitschrift Für Evidenz, Fortbildung und Qualität Im Gesundheitswesen
https://www.readbyqxmd.com/read/28514255/a-conceptual-framework-for-updating-the-definition-of-pain
#8
LETTER
Jonas Tesarz, Wolfgang Eich
No abstract text is available yet for this article.
June 2017: Pain
https://www.readbyqxmd.com/read/28455650/-use-of-cognitive-aids-in-pediatric-emergency-care-interdisciplinary-consensus-statement
#9
REVIEW
S Wirtz, C Eich, K Becke, S Brenner, A Callies, U Harding, C Höhne, F Hoffmann, J Kaufmann, B Landsleitner, H Marung, T Nicolai, F Reifferscheid, U Trappe, P Jung
Preclinical pediatric emergencies are rare events and are therefore often associated with stress and uncertainty for emergency medical service personnel. To ensure adequate treatment of pediatric patients a variety of different cognitive aids exist (e.g. books, apps, rulers, weight-adapted bag systems). Especially the size specifications of the medical equipment and the dosage of emergency medication are individually very different in children and are dependent on parameters, such as body height and weight...
April 28, 2017: Der Anaesthesist
https://www.readbyqxmd.com/read/28448985/total-skin-electron-beam-therapy-as-part-of-multimodal-treatment-strategies-for-primary-cutaneous-t-cell-lymphoma
#10
Khaled Elsayad, Katharina H Susek, Hans T Eich
Total-skin electron beam therapy (TSEBT) is one of most effective treatments that has been used for cutaneous T-cell lymphoma. Low-dose TSEBT regimens (10-12 Gy) appear to be an effective alternative to conventional-dose TSEBT (30-36 Gy), yielding short-term remission of cutaneous manifestations with minimal toxicity. TSEBT can be administered to patients any time after a diagnosis of mycosis fungoides (MF). Patients requiring rapid relief from cutaneous lesions or symptoms may particularly benefit from TSEBT as an initial therapy...
2017: Oncology Research and Treatment
https://www.readbyqxmd.com/read/28444430/successful-treatment-of-a%C3%A2-rare-case-of-ameloblastic-fibrosarcoma-with-radiation-therapy
#11
Michael Oertel, Gabriele Reinartz, Sergiu Scobioala, Hans Theodor Eich
Sarcomas are rare diseases of the head and neck region, representing around 1% of all malignancies. Amongst them, ameloblastic fibrosarcoma (AFS) is of even greater rarity, with less than 100 cases reported in the literature. Consequently, no standard treatment or guidelines have been made available. Surgery is often performed as primary therapy, but may be limited due to anatomical or functional reasons. We present a case of AFS successfully treated by postoperative radiation therapy. A detailed case study is provided, followed by a review of the English-language literature focusing on the role of radiation therapy...
April 25, 2017: Strahlentherapie und Onkologie: Organ der Deutschen Röntgengesellschaft ... [et Al]
https://www.readbyqxmd.com/read/28429075/toward-personalized-management-in-bladder-cancer-the-promise-of-novel-molecular-taxonomy
#12
REVIEW
Marie-Lisa Eich, Lars Dyrskjøt, George J Netto
Empowered by the recent advances in next generation sequencing and bioinformatics technology, an unprecedented wave of integrated transcriptomic and genomic studies have impacted the field of bladder cancer. These studies not only have confirmed previously charted genetic pathways in bladder cancer development but also have led to the discovery of numerous additional crucial driver genetic alterations. As a result, a novel genomic-based taxonomy is emerging that promises to better define clinically relevant intrinsic subtypes of bladder cancer...
April 21, 2017: Virchows Archiv: An International Journal of Pathology
https://www.readbyqxmd.com/read/28422527/attitudes-toward-stimulant-treatment-of-offspring-of-adult-patients-with-attention-deficit-hyperactivity-disorder
#13
Carlos Canela, Anna Buadze, Anish Dube, Dominique Eich, Michael Liebrenz
AIM: The objective of this study was to investigate how adult patients with attention-deficit/hyperactivity disorder viewed the testing and use of stimulants in their children. METHODS: Using a qualitative approach, we interviewed 32 outpatients from a special care unit of a university hospital. RESULTS: Emerging themes centered around concerns about the right age to test children and opinions about stimulant treatment ranging from unreserved agreement to reluctance, as well as the need for a shared decision with the child...
June 2017: Journal of Child and Adolescent Psychopharmacology
https://www.readbyqxmd.com/read/28421273/-definition-classification-clinical-diagnosis-and-prognosis-of-fibromyalgia-syndrome-updated-guidelines-2017-and-overview-of-systematic-review-articles
#14
W Eich, K-J Bär, M Bernateck, M Burgmer, C Dexl, F Petzke, C Sommer, A Winkelmann, W Häuser
BACKGROUND: The regular update of the guidelines on fibromyalgia syndrome, AWMF number 145/004, was scheduled for April 2017. METHODS: The guidelines were developed by 13 scientific societies and 2 patient self-help organizations coordinated by the German Pain Society. Working groups (n =8) with a total of 42 members were formed balanced with respect to gender, medical expertise, position in the medical or scientific hierarchy and potential conflicts of interest...
April 18, 2017: Der Schmerz
https://www.readbyqxmd.com/read/28383919/oscillating-magnetoresistance-in-graphene-p-n-junctions-at-intermediate-magnetic-fields
#15
Hiske Overweg, Hannah Eggimann, Ming-Hao Liu, Anastasia Varlet, Marius Eich, Pauline Simonet, Yongjin Lee, Kenji Watanabe, Takashi Taniguchi, Klaus Richter, Vladimir I Fal'ko, Klaus Ensslin, Thomas Ihn
We report on the observation of magnetoresistance oscillations in graphene p-n junctions. The oscillations have been observed for six samples, consisting of single-layer and bilayer graphene, and persist up to temperatures of 30 K, where standard Shubnikov-de Haas oscillations are no longer discernible. The oscillatory magnetoresistance can be reproduced by tight-binding simulations. We attribute this phenomenon to the modulated densities of states in the n- and p-regions.
April 6, 2017: Nano Letters
https://www.readbyqxmd.com/read/28383193/news-from-the-pediatric-anesthesia-societies-the-german-scientific-working-group-for-paediatric-anaesthesia-wissenschaftlicher-arbeitskreis-kinderan%C3%A3-sthesie-wakka
#16
Karin Becke, Christoph Bernhard Eich, Claudia Höhne
No abstract text is available yet for this article.
May 2017: Paediatric Anaesthesia
https://www.readbyqxmd.com/read/28382449/fate-of-copper-nickel-and-zinc-after-biogas-digestate-application-to-three-different-soil-types
#17
Ivan Dragicevic, Susanne Eich-Greatorex, Trine Aulstad Sogn, Roar Linjordet, Tore Krogstad
Soil application of organic residues from anaerobic digestion of municipal food waste and/or sewage sludge may introduce considerable amounts of heavy metals into the environment. In a column leaching experiment, mobility and release of Cu, Ni and Zn were investigated in three contrasting soils (sand, silt, loam) fertilized with biogas digestates of different origin. The effect of commercial digestates, based on food waste and sewage sludge, was compared to that of experimental digestates based on animal manure and whey permeate with or without fish ensilage, as well as untreated manure, mineral fertilizer and an untreated control...
May 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28378016/band-structure-evolution-during-the-ultrafast-ferromagnetic-paramagnetic-phase-transition-in-cobalt
#18
Steffen Eich, Moritz Plötzing, Markus Rollinger, Sebastian Emmerich, Roman Adam, Cong Chen, Henry Cornelius Kapteyn, Margaret M Murnane, Lukasz Plucinski, Daniel Steil, Benjamin Stadtmüller, Mirko Cinchetti, Martin Aeschlimann, Claus M Schneider, Stefan Mathias
The evolution of the electronic band structure of the simple ferromagnets Fe, Co, and Ni during their well-known ferromagnetic-paramagnetic phase transition has been under debate for decades, with no clear and even contradicting experimental observations so far. Using time- and spin-resolved photoelectron spectroscopy, we can make a movie on how the electronic properties change in real time after excitation with an ultrashort laser pulse. This allows us to monitor large transient changes in the spin-resolved electronic band structure of cobalt for the first time...
March 2017: Science Advances
https://www.readbyqxmd.com/read/28372367/fast-piezoelectric-valve-offering-controlled-gas-injection-in-magnetically-confined-fusion-plasmas-for-diagnostic-and-fuelling-purposes
#19
M Griener, O Schmitz, K Bald, D Bösser, M Cavedon, P De Marné, T Eich, G Fuchert, A Herrmann, A Kappatou, T Lunt, V Rohde, B Schweer, M Sochor, U Stroth, A Terra, E Wolfrum
In magnetically confined fusion plasmas controlled gas injection is crucial for plasma fuelling as well as for various diagnostic applications such as active spectroscopy. We present a new, versatile system for the injection of collimated thermal gas beams into a vacuum chamber. This system consists of a gas pressure chamber, sealed by a custom made piezo valve towards a small capillary for gas injection. The setup can directly be placed inside of the vacuum chamber of fusion devices as it is small and immune against high magnetic fields...
March 2017: Review of Scientific Instruments
https://www.readbyqxmd.com/read/28333492/perceptual-and-memory-inhibition-deficits-in-clinically-healthy-older-adults-are-associated-with-region-specific-doubly-dissociable-patterns-of-cortical-thinning
#20
Teal S Eich, Qolamreza R Razlighi, Yaakov Stern
Converging evidence suggests that the cognitive control processes that enable the inhibition of irrelevant information on a perceptual versus a memorial basis are qualitatively different and are underlain by unique neural systems that may be affected differentially in aging. In the current study, we investigated whether individual differences in performance on these 2 types of inhibitory processes were attributable to region-specific patterns of cortical thinning. Clinically healthy older adults completed a pair of behavioral memory and perceptual inhibition tasks and then underwent structural brain imaging...
June 2017: Behavioral Neuroscience
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