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https://www.readbyqxmd.com/read/28651424/estimated-glomerular-filtration-rate-renal-scan-and-volumetric-assessment-of-the-kidney-before-and-after-partial-nephrectomy-a-review-of-the-current-literature
#1
Riccardo G Bertolo, Homayoun Zargar, Riccardo Autorino, Cristian Fiori, Jihad H Kaouk, Paul Russo, Robert H Thompson, Francesco Porpiglia
INTRODUCTION: The best method for assessing renal function after partial nephrectomy (PN) continues to be a matter of debate. Early studies evaluated kidney function by measuring serum creatinine (sCr) and/or the estimated glomerular filtration rate (eGFR), potentially underestimating the contribution of the contralateral kidney in masking alterations in renal function. Since then, researchers have studied the operated renal unit with the aid of nuclear renal scans (RS). However, taking into consideration the importance of the amount of renal parenchyma spared or sacrificed during PN, many novel methods have been proposed for determining kidney volume before and after PN...
June 23, 2017: Minerva Urologica e Nefrologica, the Italian Journal of Urology and Nephrology
https://www.readbyqxmd.com/read/28651252/combined-diffusion-tensor-and-magnetic-resonance-spectroscopic-imaging-methodology-for-automated-regional-brain-analysis-application-in-a-normal-pediatric-population
#2
Nirmalya Ghosh, Barbara Holshouser, Udo Oyoyo, Stanley Barnes, Karen Tong, Stephen Ashwal
During human brain development, anatomic regions mature at different rates. Quantitative anatomy-specific analysis of longitudinal diffusion tensor imaging (DTI) and magnetic resonance spectroscopic imaging (MRSI) data may improve our ability to quantify and categorize these maturational changes. Computational tools designed to quickly fuse and analyze imaging information from multiple, technically different datasets would facilitate research on changes during normal brain maturation and for comparison to disease states...
June 27, 2017: Developmental Neuroscience
https://www.readbyqxmd.com/read/28651106/computer-based-speech-therapy-for-childhood-speech-sound-disorders
#3
REVIEW
Lisa Furlong, Shane Erickson, Meg E Morris
BACKGROUND: With the current worldwide workforce shortage of Speech-Language Pathologists, new and innovative ways of delivering therapy to children with speech sound disorders are needed. Computer-based speech therapy may be an effective and viable means of addressing service access issues for children with speech sound disorders. AIM: To evaluate the efficacy of computer-based speech therapy programs for children with speech sound disorders. METHOD: Studies reporting the efficacy of computer-based speech therapy programs were identified via a systematic, computerised database search...
June 15, 2017: Journal of Communication Disorders
https://www.readbyqxmd.com/read/28651085/evolution-of-monitoring-for-giardia-and-cryptosporidium-in-water
#4
REVIEW
Artemis Efstratiou, Jerry Ongerth, Panagiotis Karanis
This review describes the evolution of monitoring methodology for Cryptosporidium and Giardia in water since the 1970's. Methods in current use for Giardia and Cryptosporidium in water are highlighted, though attention is given to all available published methods by country and continent. The review is intended to stimulate research leading to future improvements and further developments in monitoring methodology for Giardia, Cryptosporidium and other waterborne protozoan parasites in water.
June 18, 2017: Water Research
https://www.readbyqxmd.com/read/28651070/assessment-of-temporal-predictive-models-for-health-care-using-a-formal-method
#5
Ward van Breda, Mark Hoogendoorn, A E Eiben, Matthias Berking
Recent developments in the field of sensor devices provide new possibilities to measure a variety of health related aspects in a precise and fine-grained manner. Subsequently, more empirical data will be generated than ever before. While this greatly improves the opportunities for creating accurate predictive models, other types of models besides the more traditional machine learning approaches can provide insights into temporal relationships in the data. Models that express temporal relationships between states in a mathematical manner are examples of such models...
June 17, 2017: Computers in Biology and Medicine
https://www.readbyqxmd.com/read/28650854/recent-developments-in-deuterium-oxide-tracer-approaches-to-measure-rates-of-substrate-turnover-implications-for-protein-lipid-and-nucleic-acid-research
#6
Matthew S Brook, Daniel J Wilkinson, Philip J Atherton, Ken Smith
PURPOSE OF REVIEW: Methods that inform on dynamic metabolism that can be applied to clinical populations to understand disease progression and responses to therapeutic interventions are of great importance. This review perspective will highlight recent advances, development, and applications of the multivalent stable isotope tracer deuterium oxide (D2O) to the study of substrate metabolism with particular reference to protein, lipids, and nucleic acids, and how these methods can be readily applied within clinical and pharmaceutical research...
June 24, 2017: Current Opinion in Clinical Nutrition and Metabolic Care
https://www.readbyqxmd.com/read/28650850/systemic-aminoglycosides-induced-vestibulotoxicity-in-humans
#7
Ruth Van Hecke, Vincent Van Rompaey, Floris L Wuyts, Laura Leyssens, Leen Maes
OBJECTIVES: This systematic review aimed to investigate the prevalence and characteristics of vestibular adverse effects of aminoglycoside (AG) therapy in humans and to analyze objective vestibular tests for the detection of AG-induced vestibulotoxicity. DESIGN: PubMed, Cochrane Database, Web of Science, and reference lists of all included studies were screened by two independent researchers. The Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) guidelines were followed...
June 23, 2017: Ear and Hearing
https://www.readbyqxmd.com/read/28650213/visualisation-of-upper-limb-activity-using-spirals-a-new-approach-to-the-assessment-of-daily-prosthesis-usage
#8
Alix Chadwell, Laurence Kenney, Malcolm Granat, Sibylle Thies, John S Head, Adam Galpin
BACKGROUND: Current outcome measures used in upper limb myoelectric prosthesis studies include clinical tests of function and self-report questionnaires on real-world prosthesis use. Research in other cohorts has questioned both the validity of self-report as an activity assessment tool and the relationship between clinical functionality and real-world upper limb activity. Previously,(1) we reported the first results of monitoring upper limb prosthesis use. However, the data visualisation technique used was limited in scope...
June 1, 2017: Prosthetics and Orthotics International
https://www.readbyqxmd.com/read/28649904/debiasing-health-related-judgments-and-decision-making-a-systematic-review
#9
Ramona Ludolph, Peter J Schulz
BACKGROUND: Being confronted with uncertainty in the context of health-related judgments and decision making can give rise to the occurrence of systematic biases. These biases may detrimentally affect lay persons and health experts alike. Debiasing aims at mitigating these negative effects by eliminating or reducing the biases. However, little is known about its effectiveness. This study seeks to systematically review the research on health-related debiasing to identify new opportunities and challenges for successful debiasing strategies...
June 1, 2017: Medical Decision Making: An International Journal of the Society for Medical Decision Making
https://www.readbyqxmd.com/read/28649615/imaging-parkinson-s-disease-below-the-neck
#10
Per Borghammer, Karoline Knudsen, Tatyana D Fedorova, David J Brooks
Parkinson's disease is a systemic disorder with widespread and early α-synuclein pathology in the autonomic and enteric nervous systems, which is present throughout the gastrointestinal canal prior to diagnosis. Gastrointestinal and genitourinary autonomic symptoms often predate clinical diagnosis by several years. It has been hypothesized that progressive α-synuclein aggregation is initiated in hyperbranched, non-myelinated neuron terminals, and may subsequently spread via retrograde axonal transport. This would explain why autonomic nerves are so prone to formation of α-synuclein pathology...
2017: NPJ Parkinson's Disease
https://www.readbyqxmd.com/read/28649590/enhancing-data-visualisation-to-capture-the-simulator-sickness-phenomenon-on-the-usefulness-of-radar-charts
#11
Romain Chaumillon, Thomas Romeas, Charles Paillard, Delphine Bernardin, Guillaume Giraudet, Jean-François Bouchard, Jocelyn Faubert
The data presented in this article are related to the research article entitled "The use of transdermal scopolamine to solve methodological issues raised by gender differences in susceptibility to simulator sickness" (Chaumillon et al., 2017) [1]. In an outstanding first demonstration, Kennedy et al. [2] showed that the Simulator Sickness Questionnaire (SSQ) is an appropriate tool to suit the purposes of characterizing motion sickness experienced in virtual environments. This questionnaire has since been used in many scientific studies...
August 2017: Data in Brief
https://www.readbyqxmd.com/read/28649312/the-eu-aims-longitudinal-european-autism-project-leap-design-and-methodologies-to-identify-and-validate-stratification-biomarkers-for-autism-spectrum-disorders
#12
Eva Loth, Tony Charman, Luke Mason, Julian Tillmann, Emily J H Jones, Caroline Wooldridge, Jumana Ahmad, Bonnie Auyeung, Claudia Brogna, Sara Ambrosino, Tobias Banaschewski, Simon Baron-Cohen, Sarah Baumeister, Christian Beckmann, Michael Brammer, Daniel Brandeis, Sven Bölte, Thomas Bourgeron, Carsten Bours, Yvette de Bruijn, Bhismadev Chakrabarti, Daisy Crawley, Ineke Cornelissen, Flavio Dell' Acqua, Guillaume Dumas, Sarah Durston, Christine Ecker, Jessica Faulkner, Vincent Frouin, Pilar Garces, David Goyard, Hannah Hayward, Lindsay M Ham, Joerg Hipp, Rosemary J Holt, Mark H Johnson, Johan Isaksson, Prantik Kundu, Meng-Chuan Lai, Xavier Liogier D'ardhuy, Michael V Lombardo, David J Lythgoe, René Mandl, Andreas Meyer-Lindenberg, Carolin Moessnang, Nico Mueller, Laurence O'Dwyer, Marianne Oldehinkel, Bob Oranje, Gahan Pandina, Antonio M Persico, Amber N V Ruigrok, Barbara Ruggeri, Jessica Sabet, Roberto Sacco, Antonia San José Cáceres, Emily Simonoff, Roberto Toro, Heike Tost, Jack Waldman, Steve C R Williams, Marcel P Zwiers, Will Spooren, Declan G M Murphy, Jan K Buitelaar
BACKGROUND: The tremendous clinical and aetiological diversity among individuals with autism spectrum disorder (ASD) has been a major obstacle to the development of new treatments, as many may only be effective in particular subgroups. Precision medicine approaches aim to overcome this challenge by combining pathophysiologically based treatments with stratification biomarkers that predict which treatment may be most beneficial for particular individuals. However, so far, we have no single validated stratification biomarker for ASD...
2017: Molecular Autism
https://www.readbyqxmd.com/read/28649214/interactions-between-obsessional-symptoms-and-interpersonal-ambivalences-in-psychodynamic-therapy-an-empirical-case-study
#13
Shana Cornelis, Mattias Desmet, Kimberly L H D Van Nieuwenhove, Reitske Meganck, Jochem Willemsen, Ruth Inslegers, Jasper Feyaerts
The classical symptom specificity hypothesis (Blatt, 1974) particularly associates obsessional symptoms to interpersonal behavior directed at autonomy and separation from others. Cross-sectional group research, however, has yielded inconsistent findings on this predicted association, and a previous empirical case study (Cornelis et al., in press; see Chapter 2) documented obsessional pathology to be rooted in profound ambivalences between autonomous and dependent interpersonal dynamics. Therefore, in the present empirical case study, concrete operationalizations of the classical symptom specificity hypothesis are contrasted to alternative hypotheses based on the observed complexities in Chapter 2...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/28649072/investigation-of-composition-extracts-biological-activities-and-optimization-of-solanum-nigrum-l-extraction-growing-in-iran
#14
Akbar Esmaeili, Abdul Rahman Tahazadeh, Mohammad Ali Ebrahimzadeh
Raw materials including medicinal plants are gaining popularity for the production of reliable and safe medicines suitable for human. Response Surface Methodology (RSM) is a collection of mathematical and statistical techniques used for solving the optimization problems. Using the RSM method, compounds, extracts, antioxidant and antibacterial agents of methanol, hexane, chloroform and water extracts of black nightshade (Solanum nigrum) found in Iran, had been studied for this research. GC and GC/MS had been used to determine the composition of the extracts from the aerial parts of S...
March 2017: Pakistan Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/28648951/physical-activity-and-healthy-ageing-a-systematic-review-and-meta-analysis-of-longitudinal-cohort-studies
#15
REVIEW
C Daskalopoulou, B Stubbs, C Kralj, A Koukounari, M Prince, A M Prina
BACKGROUND: Older people constitute a significant proportion of the total population and their number is projected to increase by more than half by 2050. This increasing probability of late survival comes with considerable individual, economic and social impact. Physical activity (PA) can influence the ageing process but the specific relationship with healthy ageing (HA) is unclear. METHODS: We conducted a systematic review and meta-analysis of longitudinal studies examining the associations of PA with HA...
June 22, 2017: Ageing Research Reviews
https://www.readbyqxmd.com/read/28648568/application-of-machine-learning-classification-for-structural-brain-mri-in-mood-disorders-critical-review-from-a-clinical-perspective
#16
REVIEW
Yong-Ku Kim, Kyoung-Sae Na
Mood disorders are a highly prevalent group of mental disorders causing substantial socioeconomic burden. There are various methodological approaches for identifying the underlying mechanisms of the etiology, symptomatology, and therapeutics of mood disorders; however, neuroimaging studies have provided the most direct evidence for mood disorder neural substrates by visualizing the brains of living individuals. The prefrontal cortex, hippocampus, amygdala, thalamus, ventral striatum, and corpus callosum are associated with depression and bipolar disorder...
June 22, 2017: Progress in Neuro-psychopharmacology & Biological Psychiatry
https://www.readbyqxmd.com/read/28648245/great-british-medalists-response-to-the-commentaries
#17
Lew Hardy, Matthew Barlow, Lynne Evans, Tim Rees, Tim Woodman, Chelsea Warr
Hardy et al. (2017) reported the findings of a large-scale, multisource, qualitative study that examined the commonalities of, and discriminators between, a group of super-elite (SE) and a group of elite (E) athletes who were matched on gender, sport, discipline, and era. Fifteen research teams who are actively engaged in research in the domain then provided critical commentaries on the target paper. In our response to these commentaries, we briefly remind the reader of the primary findings of the original paper and then deal with the commentaries under the subheadings: Necessary and Sufficient Conditions for Elite Performance; Mediating and Moderating Variables; Methodological Issues; Omissions; and Alternative Approaches...
2017: Progress in Brain Research
https://www.readbyqxmd.com/read/28648112/narrative-research-on-mental-health-recovery-two-sister-paradigms
#18
Gabriela Spector-Mersel, Evgeny Knaifel
BACKGROUND: Despite the breadth of narrative studies on individuals with severe mental illness, the suitability of narrative inquiry to exploring mental health recovery (MHR) has not been examined. AIMS: (1) Examining the appropriateness of narrative inquiry to studying MHR; (2) assessing the extent to which narrative studies on MHR conform to the unique features of narrative research, as a distinctive form of qualitative inquiry. METHODS: Review of empirical, theoretical and methodological literature on recovery and narrative inquiry...
June 24, 2017: Journal of Mental Health
https://www.readbyqxmd.com/read/28647545/workplace-interventions-to-improve-sitting-posture-a-systematic-review
#19
REVIEW
Paul Alan Swinton, Kay Cooper, Elizabeth Hancock
Evaluate the effectiveness of workplace interventions to improve sitting posture of workers that spend long periods of time seated at a visual display terminal. A systematic review of randomised controlled trials, non-randomised controlled trials and single-group intervention trials featuring workplace interventions with pre- and follow-up measurements of sitting posture was conducted (registered in PROSPERO, CRD#42015027648). Nine databases were searched for studies available between January 2005 and February 2016...
June 21, 2017: Preventive Medicine
https://www.readbyqxmd.com/read/28647456/improved-recovery-of-functionally-active-eosinophils-and-neutrophils-using-novel-immunomagnetic-technology
#20
Kiho Son, Manali Mukherjee, Brendan A S McIntyre, Jose C Eguez, Katherine Radford, Nicola LaVigne, Caroline Ethier, Francis Davoine, Luke Janssen, Paige Lacy, Parameswaran Nair
Clinically relevant and reliable reports derived from in vitro research are dependent on the choice of cell isolation protocols adopted between different laboratories. Peripheral blood eosinophils are conventionally isolated using density-gradient centrifugation followed by immunomagnetic selection (positive/negative) while neutrophils follow a more simplified dextran-sedimentation methodology. With the increasing sophistication of molecular techniques, methods are now available that promise protocols with reduced user-manipulations, improved efficiency, and better yield without compromising the purity of enriched cell populations...
June 21, 2017: Journal of Immunological Methods
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