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https://www.readbyqxmd.com/read/28222516/intelligent-assistive-technology-for-alzheimer-s-disease-and-other-dementias-a-systematic-review
#1
Marcello Ienca, Jotterand Fabrice, Bernice Elger, Maurizio Caon, Alessandro Scoccia Pappagallo, Reto W Kressig, Tenzin Wangmo
Intelligent assistive technologies (IATs) have the potential of offering innovative solutions to mitigate the global burden of dementia and provide new tools for dementia care. While technological opportunities multiply rapidly, clinical applications are rare as the technological potential of IATs remains inadequately translated into dementia care. In this article, the authors present the results of a systematic review and the resulting comprehensive technology index of IATs with application in dementia care...
February 7, 2017: Journal of Alzheimer's Disease: JAD
https://www.readbyqxmd.com/read/28222111/a-meta-analysis-of-the-abscopal-effect-in-preclinical-models-is-the-biologically-effective-dose-a-relevant-physical-trigger
#2
Raffaella Marconi, Silvia Strolin, Gianluca Bossi, Lidia Strigari
BACKGROUND: Preclinical in vivo studies using small animals are considered crucial in translational cancer research and clinical implementation of novel treatments. This is of paramount relevance in radiobiology, especially for any technological developments permitted to deliver high doses in single or oligo-fractionated regimens, such as stereotactic ablative radiotherapy (SABR). In this context, clinical success in cancer treatment needs to be guaranteed, sparing normal tissue and preventing the potential spread of disease or local recurrence...
2017: PloS One
https://www.readbyqxmd.com/read/28222083/patients-experiences-with-multiple-myeloma-a-meta-aggregation-of-qualitative-studies
#3
Brynja Hauksdóttir, Marianne E Klinke, Sigríður Gunnarsdóttir, Kristín Björnsdóttir
PROBLEM IDENTIFICATION: To systematically review qualitative evidence regarding patients' experiences of living with multiple myeloma. The main objective was to gain structured understanding of this experience, which is a prerequisite for advancing nursing care and ensuring it is effective.
. LITERATURE SEARCH: Qualitative research articles from January 2005 to March 2016 were located in CINAHL®, PubMed, and Scopus. Supplementary resources were found by scrutinizing reference lists and performing citation tracking...
March 1, 2017: Oncology Nursing Forum
https://www.readbyqxmd.com/read/28221914/effects-of-inoculation-procedures-on-variability-and-repeatability-of-salmonella-thermal-resistance-in-wheat-flour
#4
Ian M Hildebrandt, Bradley P Marks, Elliot T Ryser, Rossana Villa-Rojas, Juming Tang, Francisco J Garces-Vega, Sarah E Buchholz
Limited prior research has shown that inoculation methods affect thermal resistance of Salmonella in low-moisture foods; however, these effects and their repeatability have not been systematically quantified. Consequently, method variability across studies limits utility of individual data sets and cross-study comparisons. Therefore, the objective was to evaluate the effects of inoculation methodologies on stability and thermal resistance of Salmonella in a low-moisture food (wheat flour), and the repeatability of those results, based on data generated by two independent laboratories...
November 2016: Journal of Food Protection
https://www.readbyqxmd.com/read/28221665/totally-percutaneous-versus-surgical-cut-down-femoral-artery-access-for-elective-bifurcated-abdominal-endovascular-aneurysm-repair
#5
REVIEW
Madelaine Gimzewska, Alexander Ir Jackson, Su Ern Yeoh, Mike Clarke
BACKGROUND: Abdominal aortic aneurysms (AAAs) are a vascular condition with significant risk attached, particularly if they rupture. It is, therefore, critical to identify and repair these as an elective procedure before they rupture and require emergency surgery. Repair has traditionally been an open surgical technique that required a large incision across the abdomen. Endovascular abdominal aortic aneurysm repairs (EVARs) are now a common alternative. In this procedure, the common femoral artery is exposed via a cut-down approach and a graft introduced to the aneurysm in this way...
February 21, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28221075/william-r-shadish-1949-2016
#6
Thomas Cook, Kenneth Lichstein
Presents an obituary for William R. Shadish who passed away on March 27, 2016, after a long, arduous battle with prostate cancer. Shadish was a distinguished professor for the University of California, Merced. He was elected president of three organizations: American Evaluation Association (1996), Society for Research Synthesis Methodology (2013), and Society for Multivariate Experimental Psychology (2014), and received numerous national awards. (PsycINFO Database Record
February 2017: American Psychologist
https://www.readbyqxmd.com/read/28220474/buprenorphine-for-managing-opioid-withdrawal
#7
REVIEW
Linda Gowing, Robert Ali, Jason M White, Dalitso Mbewe
BACKGROUND: Managed withdrawal is a necessary step prior to drug-free treatment or as the endpoint of substitution treatment. OBJECTIVES: To assess the effects of buprenorphine versus tapered doses of methadone, alpha2-adrenergic agonists, symptomatic medications or placebo, or different buprenorphine regimens for managing opioid withdrawal, in terms of the intensity of the withdrawal syndrome experienced, duration and completion of treatment, and adverse effects...
February 21, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28220393/common-and-distinct-regulation-of-human-and-mouse-brown-and-beige-adipose-tissues-a-promising-therapeutic-target-for-obesity
#8
REVIEW
Xuejiao Liu, Christopher Cervantes, Feng Liu
Obesity, which underlies various metabolic and cardiovascular diseases, is a growing public health challenge for which established therapies are inadequate. Given the current obesity epidemic, there is a pressing need for more novel therapeutic strategies that will help adult individuals to manage their weight. One promising therapeutic intervention for reducing obesity is to enhance energy expenditure. Investigations into human brown fat and the recently discovered beige/brite fat have galvanized intense research efforts during the past decade because of their pivotal roles in energy dissipation...
February 20, 2017: Protein & Cell
https://www.readbyqxmd.com/read/28220251/triple-aim-improvement-for-individuals-services-and-society-in-dementia-care-the-dementianet-collaborative-care-approach
#9
M S Nieuwboer, A Richters, M A van der Marck
BACKGROUND: A redesigning of primary care is required to meet dementia patients' needs. In the Netherlands, current dementia care still falls short in areas including ad hoc collaboration, lack of feedback on quality to professionals involved, and insufficient implementation of established multidisciplinary guidelines. OBJECTIVE: DementiaNet is a collaborative care approach, which aims to reduce the burden of the disease on individuals, healthcare services and society via network-based care that encourages collaboration, enhances knowledge and skills and stimulates quality improvement cycles...
February 20, 2017: Zeitschrift Für Gerontologie und Geriatrie
https://www.readbyqxmd.com/read/28220105/acth-receptor-mc2r-specificity-what-do-we-know-about-underlying-molecular-mechanisms
#10
REVIEW
Davids Fridmanis, Ance Roga, Janis Klovins
Coincidentally, the release of this Research Topic in Frontiers in Endocrinology takes place 25 years after the discovery of the adrenocorticotropic hormone receptor (ACTHR) by Mountjoy and colleagues. In subsequent years, following the discovery of other types of mammalian melanocortin receptors (MCRs), ACTHR also became known as melanocortin type 2 receptor (MC2R). At present, five types of MCRs have been reported, all of which share significant sequence similarity at the amino acid level, and all of which specifically bind melanocortins (MCs)-a group of biologically active peptides generated by proteolysis of the proopiomelanocortin precursor...
2017: Frontiers in Endocrinology
https://www.readbyqxmd.com/read/28219350/women-s-experiences-of-personalised-support-for-asthma-care-during-pregnancy-a-systematic-review-of-the-literature
#11
Graham R Williamson, Anita O'Connor, Elmslie-Jones Kayleigh
BACKGROUND: Asthma and pregnancy are both sources of anxiety for women. Although there has been a focus on physiological management of asthma and pregnancy, there has been little research on the impact that personalised support can have on asthma care during pregnancy. This systematic review and narrative synthesis of the literature set out to answer the question 'What are women's experiences of asthma care, its management and education, during pregnancy?' METHODS: This systematic review was carried out using accepted methodology from the York Centre for Reviews and Dissemination...
February 20, 2017: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/28219247/addressing-analytical-challenges-of-the-environmental-monitoring-for-the-water-framework-directive-erm-ce100-a-new-biota-certified-reference-material
#12
Ioannis Dosis, Marina Ricci, Laszlo Majoros, Roberto Lava, Håkan Emteborg, Andrea Held, Hendrik Emons
In the context of supporting the EU Member States in the implementation of the EU Water Framework Directive (WFD), a project for the production of a fish reference material (ERM-CE100) certified for its content of the two priority substances hexachlorobenzene (HCB) and hexachlorobutadiene (HCBD) was carried out at the Joint Research Centre (JRC) of the European Commission. The starting material was naturally contaminated Wels catfish (Silurus glanis), caught in the Ebro River (Spain). A novel approach for the processing of the fish was tested that resulted in a homogeneous and stable reference material in the form of a wet paste...
February 21, 2017: Analytical Chemistry
https://www.readbyqxmd.com/read/28219026/cognitive-remediation-and-social-cognitive-training-for-violence-in-schizophrenia-a-systematic-review
#13
REVIEW
C Darmedru, C Demily, N Franck
: A significant correlation exists between violence and schizophrenia (SCZ). Recent studies matched some cognitive deficits like strong risk factors for violence with interesting applications in terms of treatment. Our objective was to conduct a systematic review of the effectiveness of cognitive remediation (CR) and social cognitive training (SCT) in the management of violent and aggressive behaviors in SCZ. METHODS: The electronic databases Pubmed, Web of Science, Cochrane Library and ScienceDirect were searched in, using combinations of terms relating to SCZ, CR and violence...
February 9, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/28218850/impact-of-phosphorylation-and-pseudo-phosphorylation-on-the-early-stages-of-aggregation-of-the-microtubule-associated-protein-tau
#14
Dmitriy V Prokopovich, John W Whittaker, Micaiah M Muthee, Azka Ahmed, Luca Larini
The microtubule associated protein tau regulates the stability of microtubules within neurons in the central nervous system. In turn, microtubules are responsible for the remodeling of the cytoskeleton that ultimately leads to the formation or pruning of new connections among neurons. As a consequence, dysfunction of tau is associated with many forms of dementia as well as Alzheimer's disease. In the brain, tau activity is regulated by its phosphorylation state. Phosphorylation is a post-translational modification of proteins that adds a phosphate group to the side chain of an amino acid...
February 20, 2017: Journal of Physical Chemistry. B
https://www.readbyqxmd.com/read/28218009/the-use-of-social-media-by-adults-with-acquired-conditions-who-use-aac-current-gaps-and-considerations-in-research
#15
Helen L Paterson
The global growth and development of social media has had a positive impact on many individuals who use augmentative and alternative communication (AAC), who use it to communicate and connect with others. Research evidence into the use of social media by adults with acquired conditions who use AAC is limited. These individuals are a heterogeneous population, who can present with a range of linguistic, cognitive and physical needs, some of which progress rapidly, making accessing social media a challenge. These issues warrant research focusing on developing interventions to support the use of social media and the impact of these interventions...
March 2017: Augmentative and Alternative Communication: AAC
https://www.readbyqxmd.com/read/28217913/what-are-the-key-elements-of-cognitive-analytic-therapy-for-psychosis-a-delphi-study
#16
Peter J Taylor, Sarah Jones, Christopher D Huntley, Claire Seddon
OBJECTIVE: There has been growing interest in the use of cognitive analytic therapy (CAT) with those facing experiences of psychosis. However, there is little research on how CAT is best applied to working with psychosis. This study aimed to identify what the key aspects of CAT for psychosis are or whether this approach requires adaptation when applied to those with experiences of psychosis, drawing on expert opinion. METHOD: An adapted Delphi methodology was used...
February 20, 2017: Psychology and Psychotherapy
https://www.readbyqxmd.com/read/28216721/methodology-series-module-7-ecologic-studies-and-natural-experiments
#17
Maninder Singh Setia
In this module, we have discussed study designs that have not been covered in the previous modules - ecologic studies and natural experiments. In an ecologic study, the unit of analysis is a group or aggregate rather than the individual. It may be the characteristics of districts, states, or countries. For example, per capita income across countries, income quintiles across districts, and proportion of college graduates in states. If the data already exist (such as global measures and prevalence of diseases, data sets such as the National Family Health Survey, census data), then ecologic studies are cheap and data are easy to collect...
January 2017: Indian Journal of Dermatology
https://www.readbyqxmd.com/read/28216557/a-methodology-to-monitor-airborne-pm10-dust-particles-using-a-small-unmanned-aerial-vehicle
#18
Miguel Alvarado, Felipe Gonzalez, Peter Erskine, David Cliff, Darlene Heuff
Throughout the process of coal extraction from surface mines, gases and particles are emitted in the form of fugitive emissions by activities such as hauling, blasting and transportation. As these emissions are diffuse in nature, estimations based upon emission factors and dispersion/advection equations need to be measured directly from the atmosphere. This paper expands upon previous research undertaken to develop a relative methodology to monitor PM10 dust particles produced by mining activities making use of small unmanned aerial vehicles (UAVs)...
February 14, 2017: Sensors
https://www.readbyqxmd.com/read/28216034/the-vitiligo-working-group-recommendations-for-narrowband-ultraviolet-b-light-phototherapy-treatment-of-vitiligo
#19
Tasneem F Mohammad, Mohammed Al-Jamal, Iltefat H Hamzavi, John E Harris, Giovanni Leone, Raúl Cabrera, Henry W Lim, Amit G Pandya, Samia M Esmat
BACKGROUND: Treatment of vitiligo with narrowband ultraviolet B light (NBUVB) is an important component of the current standard of care. However, there are no consistent guidelines regarding the dosing and administration of NBUVB in vitiligo, reflected by varied treatment practices around the world. OBJECTIVE: To create phototherapy recommendations to facilitate clinical management and identify areas requiring future research. METHODS: The Vitiligo Working Group (VWG) Phototherapy Committee addressed 19 questions regarding the administration of phototherapy over 3 conference calls...
February 15, 2017: Journal of the American Academy of Dermatology
https://www.readbyqxmd.com/read/28215657/methodological-considerations-with-data-uncertainty-in-road-safety-analysis
#20
Matthias Schlögl, Rainer Stütz
The analysis of potential influencing factors that affect the likelihood of road accident occurrence has been of major interest for safety researchers throughout the recent decades. Even though steady methodological progresses were made over the years, several impediments pertaining to the statistical analysis of crash data remain. While issues related to methodological approaches have been subject to constructive discussion, uncertainties inherent to the most fundamental part of any analysis have been widely neglected: data...
February 16, 2017: Accident; Analysis and Prevention
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