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https://www.readbyqxmd.com/read/28533559/instability-pattern-formation-in-a-liquid-metal-under-high-magnetic-fields
#1
Jun Wang, Jinshan Li, Hongchao Kou, Eric Beaugnon
Magnetic field can generate interface instability when some liquids are put close to magnetic field. A well-known interface instability is called Rosensweig instability or normal field instability. Here we report that pure liquid Co can be highly undercooled close to its Curie temperature in strong magnetic field with very high magnetization and exhibiting unique morphology instability called the normal field instability. To obtain such unique instability pattern, the sample size, undercooling and magnetic field intensity need fulfill certain condition...
May 22, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28532991/estimating-population-density-for-disease-risk-assessment-the-importance-of-understanding-the-area-of-influence-of-traps-using-wild-pigs-as-an-example
#2
Amy J Davis, Bruce Leland, Michael Bodenchuk, Kurt C VerCauteren, Kim M Pepin
Population density is a key driver of disease dynamics in wildlife populations. Accurate disease risk assessment and determination of management impacts on wildlife populations requires an ability to estimate population density alongside management actions. A common management technique for controlling wildlife populations to monitor and mitigate disease transmission risk is trapping (e.g., box traps, corral traps, drop nets). Although abundance can be estimated from trapping actions using a variety of analytical approaches, inference is limited by the spatial extent to which a trap attracts animals on the landscape...
June 1, 2017: Preventive Veterinary Medicine
https://www.readbyqxmd.com/read/28532499/laparoscopic-roux-en-y-gastric-bypass-versus-laparoscopic-mini-gastric-bypass-in-the-treatment-of-obesity-study-protocol-for-a-randomized-controlled-trial
#3
Marko Kraljević, Tarik Delko, Thomas Köstler, Elena Osto, Thomas Lutz, Sarah Thommen, Raoul A Droeser, Lincoln Rothwell, Daniel Oertli, Urs Zingg
BACKGROUND: Laparoscopic Roux-en-Y gastric bypass (LRYGB) is considered the gold standard in bariatric surgery, achieving durable long-term weight loss with improvement of obesity-related comorbidities. Lately, the laparoscopic mini gastric bypass (LMGB) has gained worldwide popularity with similar results to LRYGB in terms of weight loss and comorbidity resolution. However, there is a lack of randomized controlled trials (RCT) comparing LMGB and LRYGB. This article describes the design and protocol of a randomized controlled trial comparing the outcomes of these two bariatric procedures...
May 22, 2017: Trials
https://www.readbyqxmd.com/read/28532191/cost-effectiveness-of-omalizumab-add-on-to-standard-of-care-therapy-in-patients-with-uncontrolled-severe-allergic-asthma-in-a-brazilian-healthcare-setting
#4
Cibele Suzuki, Nilceia Lopes da Silva, Praveen Kumar, Purnima Pathak, Siew Hwa Ong
OBJECTIVE: Omalizumab add-on to standard-of-care therapy has proven to be efficacious in severe asthma patients for whom exacerbations cannot be controlled otherwise. Moreover, evidence from different healthcare settings suggests reduced healthcare resource utilization with omalizumab. Based on these findings, we aimed to assess the cost effectiveness of the addition of omalizumab to standard-of-care therapy in patients with uncontrolled severe allergic asthma in a Brazilian healthcare setting...
May 22, 2017: Journal of Medical Economics
https://www.readbyqxmd.com/read/28532033/synthesis-of-nano-sized-timolol-imprinted-polymer-via-ultrasonication-assisted-suspension-polymerization-in-silicon-oil-and-its-use-for-the-fabrication-of-timolol-voltammetric-sensor
#5
Taher Alizadeh, Mohammad Reza Ganjali, Faride Rafiei, Maedeh Akhoundian
A novel timolol voltammetric sensor based on the nano-sized molecularly imprinted polymer (nano-MIP)-modified carbon paste electrode was introduced. Timolol-imprinted polymers (MIP) were synthesized by the ultrasonic assisted suspension polymerization in silicon oil. The MIP nanoparticles were then embedded in a carbon paste (CP) electrode in order to prepare the nano-MIP-CP electrode. Timolol was extracted in the electrode for a definite time and then it was analyzed by square wave voltammetry, found to be an effective determination method...
August 1, 2017: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/28530813/enhanced-sampling-of-phase-transitions-in-coarse-grained-lipid-bilayers
#6
David N Stelter, Tom Keyes
Freezing and melting of dipalmitoylphosphatidylcholine (DPPC) bilayers are simulated in both the explicit (Wet) and implicit solvent (Dry) coarse-grained MARTINI force fields with enhanced sampling, via the isobaric, molecular dynamics version of the generalized replica exchange method (gREM). Phase transitions are described with the entropic viewpoint, based upon the statistical temperature as a function of enthalpy, TS(H) = 1/(dS(H)/dH), where S is the configurational entropy. Bilayer thickness, area per lipid, and the second-rank order parameter (P2) are calculated vs temperature in the transition range...
May 22, 2017: Journal of Physical Chemistry. B
https://www.readbyqxmd.com/read/28530480/ultrasonographic-and-histological-evaluation-of-the-effects-of-long-term-carotid-catheterization-on-cardiac-function-in-nmri-mice
#7
Anne C Teilmann, Morten B Thomsen, Elizabeth A Ihms, Nathan Pate, Jann Hau, Klas Abelson
Catheterization of laboratory mice is commonly performed in biomedical research to infuse substances and for blood sampling. One approach is to catheterize the right common carotid artery and advance the catheter until the tip is positioned in the aorta or the proximal brachiocephalic trunk. Owing to the small body size of the mouse, a catheter tends to occupy a great part of even the larger vessel lumens, and this may increase vascular resistance with potential pathophysiological impacts on the heart. The present study compared cardiac function of catheterized mice, with catheter tip placement in the brachiocephalic trunk, with sham-operated mice and non-operated control mice...
January 1, 2017: Laboratory Animals
https://www.readbyqxmd.com/read/28526876/inductive-flash-annealing-of-bulk-metallic-glasses
#8
K Kosiba, S Pauly
We developed a temperature-controlled inductive flash-annealing device, which heats bulk metallic glasses (BMGs) at defined rates of up to 200 K/s to a given temperature. Subsequent instantaneous quenching in water allows preserving the microstructures obtained at various stages of crystallization. One Zr-based and two CuZr-based BMGs were flash-annealed at the onset of crystallization with different heating rates in order to prepare advanced BMG-matrix composites. The highly reproducible composite microstructures contain uniformly dispersed crystals and a narrow crystal size distribution...
May 19, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28526046/balloon-versus-stenting-in-severe-ischaemia-of-the-leg-3-basil-3-study-protocol-for-a-randomised-controlled-trial
#9
Benjamin D Hunt, Matthew A Popplewell, Huw Davies, Lewis Meecham, Hugh Jarrett, Gareth Bate, Margaret Grant, Smitaa Patel, Catherine Hewitt, Lazaros Andronis, Jonathan J Deeks, Andrew Bradbury
BACKGROUND: Severe limb ischaemia (SLI) is defined as the presence of rest pain and/or tissue loss secondary to lower extremity atherosclerotic peripheral arterial disease. The superficial femoral and popliteal arteries are the most commonly diseased vessels in such patients and are being increasingly treated using endovascular revascularisation techniques. However, it is currently unknown whether drug-eluting stents and drug-coated balloons confer additional clinical benefits over more established techniques using plain balloons and bare metal stents, or whether they represent a cost-effective use of NHS resources...
May 19, 2017: Trials
https://www.readbyqxmd.com/read/28526045/standardization-of-platelet-releasate-products-for-clinical-applications-in-cell-therapy-a-mathematical-approach
#10
Francesco Agostini, Jerry Polesel, Monica Battiston, Elisabetta Lombardi, Stefania Zanolin, Alessandro Da Ponte, Giuseppe Astori, Cristina Durante, Mario Mazzucato
BACKGROUND: Standardized animal-free components are required for manufacturing cell-based medicinal products. Human platelet concentrates are sources of growth factors for cell expansion but such products are characterized by undesired variability. Pooling together single-donor products improves consistency, but the minimal pool sample size was never determined. METHODS: Supernatant rich in growth factors (SRGF) derived from n = 44 single-donor platelet-apheresis was obtained by CaCl2 addition...
May 19, 2017: Journal of Translational Medicine
https://www.readbyqxmd.com/read/28525580/a-new-formulation-of-random-genetic-drift-and-its-application-to-the-evolution-of-cell-populations
#11
Yuxin Chen, Ding Tong, Chung-I Wu
Random genetic drift, or stochastic change in gene frequency, is a fundamental evolutionary force that is usually defined within the ideal Wright-Fisher (WF) population. However, as the theory is increasingly applied to populations that deviate strongly from the ideal model, a paradox of random drift has emerged. When drift is defined by the WF model, it becomes stronger as the population size, N, decreases. However, the intensity of competition decreases when N decreases and, hence, drift might become weaker...
May 19, 2017: Molecular Biology and Evolution
https://www.readbyqxmd.com/read/28521412/microrna-335-and-its-target-rock1-synergistically-influence-tumor-progression-and-prognosis-in-osteosarcoma
#12
Yong Wang, Ningning Wang, Xiandong Zeng, Jie Sun, Guangbin Wang, Huimian Xu, Wei Zhao
MicroRNA (miR)-335 and Rho-associated serine-threonine protein kinase 1 (Rock1) is ectopically expressed in multiple malignant tumors including osteosarcoma. The present study aimed to clarify whether the combined ectopically expressed miR-335 and Rock1 was correlated with clinicopathological features and prognosis in patients with osteosarcoma. The expression of miR-335 and Rock1 in 91 osteosarcoma tissue samples and 47 noncancerous bone tissues were determined respectively by in situ hybridization and immunohistochemistry...
May 2017: Oncology Letters
https://www.readbyqxmd.com/read/28521094/critical-assessment-of-photoionization-efficiency-measurements-for-characterization-of-soot-precursor-species
#13
K Olof Johansson, Judit Zádor, Paolo Elvati, Matthew F Campbell, Paul E Schrader, Nicole K Richards-Henderson, Kevin R Wilson, Angela Violi, Hope A Michelsen
We present a critical evaluation of photoionization efficiency (PIE) measurements coupled with aerosol mass spectrometry for the identification of condensed soot-precursor species extracted from a premixed atmospheric-pressure ethylene/oxygen/nitrogen flame. Definitive identification of isomers by any means is complicated by the large number of potential isomers at masses likely to comprise particles at flame temperatures. This problem is compounded using PIE measurements by the similarity in ionization energies and PIE-curve shapes among many of these isomers...
May 18, 2017: Journal of Physical Chemistry. A
https://www.readbyqxmd.com/read/28520974/the-neuropsychological-assessment-of-justice-involved-men-descriptive-analysis-preliminary-data-and-a-case-for-group-specific-norms
#14
Casey LaDuke, David DeMatteo, Kirk Heilbrun, Jennifer Gallo, Thomas Swirsky-Sacchetti
Objective: Neuropsychological expertise has played an increasing role in legal decision-making in criminal contexts. Valid neuropsychological evidence in criminal forensic contexts requires normative data that are representative of justice-involved individuals. Unfortunately, existing normative data appear unlikely to represent justice-involved individuals due to significant demographic and clinical factors specific to this population. As a result, the interpretation of neuropsychological performance with justice-involved individuals using existing normative data may increase the risk of inaccurate description, invalid clinical conceptualization, misdiagnosis of impairment, and misattribution of deficits in functional-legal capacities...
May 18, 2017: Archives of Clinical Neuropsychology: the Official Journal of the National Academy of Neuropsychologists
https://www.readbyqxmd.com/read/28514508/methadone-for-neuropathic-pain-in-adults
#15
REVIEW
Ewan D McNicol, McKenzie C Ferguson, Roman Schumann
BACKGROUND: This review replaces an earlier review, "Methadone for chronic non-cancer pain in adults". This review serves to update the original and includes only studies of neuropathic pain. Methadone belongs to a class of analgesics known as opioids, that are considered the cornerstone of therapy for moderate-to-severe postsurgical pain and pain due to life-threatening illnesses; however, their use in neuropathic pain is controversial. Methadone has many characteristics that differentiate it from other opioids, which suggests that it may have a different efficacy and safety profile...
May 17, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28514285/association-of-abcb1-c3435t-polymorphism-with-the-susceptibility-to-osteonecrosis-of-the-femoral-head-a-meta-analysis
#16
Yu Zhang, Hui Xie, Dewei Zhao, Benjie Wang, Lei Yang, Qingyu Meng
BACKGROUND AND OBJECTIVE: The exploration for the etiology of osteonecrosis of the femoral head (ONFH) has got some promising findings, but the morbidity of ONFH is still not under control. The C3435T polymorphism of ATP-binding cassette subfamily B member 1 (ABCB1) gene has been reported to possess significant influence on ONFH onset, but relevant outcomes remain conflicting rather than conclusive. Therefore, a meta-analysis was useful to pool these results together for a more reliable conclusion...
May 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28513854/verification-of-dose-profiles-generated-by-the-convolution-algorithm-of-the-gamma-knife-%C3%A2-radiosurgery-planning-system
#17
Hyun-Tai Chung, Jeong-Hoon Park, Kook Jin Chun
PURPOSE: A convolution algorithm that takes into account electron-density inhomogeneity was recently introduced to calculate dose distributions for the Gamma Knife (GK) Perfexion(™) treatment planning program. The accuracies of the dose distributions computed using the convolution method were assessed using an anthropomorphic phantom and film dosimetry. METHODS: Absorbed-dose distributions inside a phantom (CIRS Radiosurgery Head Phantom, Model 605) were calculated using the convolution method of the GK treatment-planning software (Leksell Gamma Plan(®) version 10...
May 17, 2017: Medical Physics
https://www.readbyqxmd.com/read/28508332/occurrence-of-diazepam-and-its-metabolites-in-wastewater-and-surface-waters-in-beijing
#18
Congcong Wang, Linlin Hou, Jing Li, Zeqiong Xu, Tingting Gao, Jun Yang, Huafang Zhang, Xiqing Li, Peng Du
Occurrence of diazepam and its metabolites, nordiazepam, temazepam, and oxazepam in the water environment in Beijing was investigated. Samples were collected from four rivers flowing through the city and from all the thirteen sewage treatment plants in the urban area. Average influent concentrations of diazepman, temazepam, and oxazepam in 2013 summer ranged from 0.9 to 7.1, 1.5 to 3.4, and 2.9 to 12.4 ng L(-1), respectively, whereas nordiazepam concentrations were below quantification limit on the majority of sampling dates...
May 15, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28508076/machine-learning-of-accurate-energy-conserving-molecular-force-fields
#19
Stefan Chmiela, Alexandre Tkatchenko, Huziel E Sauceda, Igor Poltavsky, Kristof T Schütt, Klaus-Robert Müller
Using conservation of energy-a fundamental property of closed classical and quantum mechanical systems-we develop an efficient gradient-domain machine learning (GDML) approach to construct accurate molecular force fields using a restricted number of samples from ab initio molecular dynamics (AIMD) trajectories. The GDML implementation is able to reproduce global potential energy surfaces of intermediate-sized molecules with an accuracy of 0.3 kcal mol(-1) for energies and 1 kcal mol(-1) Å̊(-1) for atomic forces using only 1000 conformational geometries for training...
May 2017: Science Advances
https://www.readbyqxmd.com/read/28507475/macrophage-migration-inhibitory-factor-173-g-c-polymorphism-and-risk-of-tuberculosis-a-meta-analysis
#20
Mohammad Naderi, Mohammad Hashemi, Hossein Ansari
The aim of the present meta-analysis was to find out the impact of MIF -173 G > C polymorphism on risk of tuberculosis (TB). We conducted a search of case-control studies on the associations of -173 G > C variant of MIF with susceptibility to tuberculosis in PubMed, ISI Web of Science, and Scopus. We extracted the data from eligible studies and achieved a meta-analysis to examine the relationship between MIF -173 G > C polymorphism and the risk of TB. Odds ratios (ORs) with the corresponding 95 % confidence intervals (CIs) were pooled to find out the impact of MIF -173G > C promoter polymorphism on TB risk...
2017: EXCLI journal
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