keyword
MENU ▼
Read by QxMD icon Read
search

Follicular thyroid

keyword
https://www.readbyqxmd.com/read/28723963/impact-of-thyroid-function-abnormalities-on-reproductive-hormones-during-menstrual-cycle-in-premenopausal-hiv-infected-females-at-nauth-nnewi-nigeria
#1
Nkiruka Rose Ukibe, Solomon Nwabueze Ukibe, Obiageli Fidelia Emelumadu, Chinedum Charles Onyenekwe, Joseph Eberendu Ahaneku, Anthony Osita Igwegbe, Ifeoma Nwamaka Monago, Amobi Linus Ilika
BACKGROUND: This was a prospective study designed to evaluate the impact of thyroid function abnormalities on reproductive hormones during menstrual cycle in HIV infected females at Nnamdi Azikiwe University Teaching Hospital Nnewi, South-East Nigeria. METHODS: The study randomly recruited 35 Symptomatic HIV infected females and 35 Symptomatic HIV infected females on antiretroviral therapy (HAART) for not less than six weeks from an HIV clinic and 40 apparently heathy control females among the hospital staff of NAUTH Nnewi...
2017: PloS One
https://www.readbyqxmd.com/read/28719972/risk-stratification-of-thyroid-nodules-with-atypia-of-undetermined-significance-follicular-lesion-of-undetermined-significance-aus-flus-cytology-using-ultrasonography-patterns-defined-by-the-2015-ata-guidelines
#2
Ji Hye Lee, Kyunghwa Han, Eun-Kyung Kim, Hee Jung Moon, Jung Hyun Yoon, Vivian Y Park, Jin Young Kwak
PURPOSE: The purpose of this study was to evaluate the predictive value of ultrasonography (US) patterns based on the 2015 American Thyroid Association (ATA) guidelines for malignancy in atypia of undetermined significance or follicular lesion of undetermined significance (AUS/FLUS) nodules. METHODS: From January 2014 to August 2015, 133 thyroid nodules that were initially diagnosed as AUS/FLUS on fine needle aspiration (FNA) were included in this study. Each nodule was assigned a category with US patterns defined by the ATA guidelines...
July 1, 2017: Annals of Otology, Rhinology, and Laryngology
https://www.readbyqxmd.com/read/28717394/immunohistochemical-expression-of-er-%C3%AE-and-pr-in-papillary-thyroid-carcinoma
#3
Marwa Mohammed Serag Eldien, Asmaa Gaber Abdou, Tarek Rageh, Eman Abdelrazek, Enas Elkholy
Papillary thyroid carcinoma (PTC) is the most common thyroid cancer with multiple risk factors including exposure to ionising radiation. Oestrogens contribute to papillary carcinoma development by promoting cell proliferation and invasion of mutated epithelial follicular cells. The present study aimed to assess ER-α and PR expression in PTC and to correlate their expression with the clinicopathological parameters in this cancer. This study included 62 primary and six metastatic papillary thyroid carcinoma cases...
2017: Ecancermedicalscience
https://www.readbyqxmd.com/read/28715746/pfoa-induced-metabolism-disturbance-and-multi-generational-reproductive-toxicity-in-oryzias-latipes
#4
Jin Wuk Lee, Jae-Woo Lee, Kyungtae Kim, Yu-Jin Shin, Jieun Kim, Suhkmann Kim, Heejung Kim, Pilje Kim, Kyunghwa Park
The aims of this study were to examine multi-generational reproductive toxicity and metabolism disturbances in Oryzias latipes exposed to 0.3, 3, and 30mg/L PFOA for 259-day. The highest concentration of PFOA suppressed fecundity over three generations from F0 to F2 and sac-fry survival rate in F2 generation, indicating that PFOA resulted in multi-generational reproductive toxicity (p<0.05). Histologically, in F1 and F2 generations, O. latipes exposed to 30mg/L PFOA revealed accelerated gonad development, and the atrophy and degeneration of thyroid follicular cell...
June 27, 2017: Journal of Hazardous Materials
https://www.readbyqxmd.com/read/28714532/thyroid-nodules-classified-as-atypia-or-follicular-lesions-of-undetermined-significance-deserve-further-research-analysis-of-305-surgically-confirmed-nodules
#5
S Turkyilmaz, M Ulusahin, B Celebi, A B Cekic, S Mungan, U Kucuktulu, A Tasdelen, A Guner, A Cinel
OBJECTIVE: The objective of the present study was to determine the malignancy risk for nodules categorised as atypia or follicular lesions of undetermined significance atypia of undetermined significance/follicular lesion of undetermined significance (AUS/FLUS) and to investigate the predictors of malignancy. METHODS: All nodules diagnosed as AUS/FLUS on fine needle aspiration (FNAs) performed between January 2011 and December 2015 were retrospectively reviewed...
July 17, 2017: Cytopathology: Official Journal of the British Society for Clinical Cytology
https://www.readbyqxmd.com/read/28713699/transoral-thyroidectomy-why-is-it-needed
#6
REVIEW
Gianlorenzo Dionigi, Matteo Lavazza, Chei-Wei Wu, Hui Sun, Xiaoli Liu, Ralph P Tufano, Hoon Yub Kim, Jeremy D Richmon, Angkoon Anuwong
Transoral thyroidectomy (TOT) represents reasonably the desirable minimally invasive approach to the gland due to the scarless non-visible incisions, the limited distance between the gland and the access that minimize tissue dissection and respect of the surgical anatomical planes. Patients are routinely selected according to an extensive inclusion criteria: (I) ultrasonographically (US) estimated thyroid diameter not larger than 10 cm; (II) US gland volume ≤45 mL; (III) nodule size ≤50 mm; (IV) a benign tumor, such as a thyroid cyst, single-nodular goiter, or multinodular goiter; (V) follicular neoplasm; (VI) papillary microcarcinoma without lymph node metastasis...
June 2017: Gland Surgery
https://www.readbyqxmd.com/read/28711609/the-epigenetic-landscape-of-differentiated-thyroid-cancer
#7
REVIEW
Sylvia L Asa, Shereen Ezzat
Differentiated thyroid carcinoma of follicular cell-derivation is the most common endocrine neoplasm with a rapidly increasing incidence. The majority represent papillary carcinomas; more rarely, they are follicular carcinomas. The vast majority have indolent behavior, however a significant proportion progress to develop lymph node metastases and a smaller proportion disseminate systemically. While common and frequent genetic events have been described to underlie the development of these neoplasms, the factors contributing to differing behaviors among tumors with similar genetic alterations remain unclear...
July 12, 2017: Molecular and Cellular Endocrinology
https://www.readbyqxmd.com/read/28710706/synchronous-and-metastatic-papillary-and-follicular-thyroid-carcinomas-with-unique-molecular-signatures
#8
Vincent Cracolici, Ibro Mujacic, Sabah Kadri, Mir Alikhan, Nifang Niu, Jeremy P Segal, Lauren E Rosen, David H Sarne, Adam Morgan, Samy Desouky, Nicole A Cipriani
Despite the relatively high prevalence of thyroid cancer, the occurrence of multiple synchronous, distinct subtypes of primary thyroid carcinoma is uncommon. The incidental finding of papillary thyroid microcarcinoma in a gland with a biologically relevant follicular or medullary carcinoma is more frequent than the synchronous occurrence of multiple clinically significant carcinomas. We report a case of synchronous papillary and follicular thyroid carcinomas metastatic to lymph node and bone, respectively. Next generation sequencing showed BRAF V600E mutation in the primary papillary carcinoma and NRAS Q61R mutation in the primary follicular carcinoma and bony metastasis...
July 14, 2017: Endocrine Pathology
https://www.readbyqxmd.com/read/28709933/identification-of-novel-biomarker-and-therapeutic-target-candidates-for-diagnosis-and-treatment-of-follicular-carcinoma
#9
Xianyin Lai, Christopher B Umbricht, Kurt Fisher, Justin Bishop, Qiuying Shi, Shaoxiong Chen
Distinguishing follicular carcinoma from follicular adenoma, based on cytomorphological features, has always been challenging to cytopathologists. Identification of biomarkers for improving diagnostic accuracy is important for clinical management. Meanwhile, it is critical to identify therapeutic target candidates for treatment of follicular carcinoma. Currently, no reliable diagnostic protein biomarkers and therapeutic targets are available. To explore novel protein biomarker and therapeutic target candidates, a liquid chromatography-tandem mass spectrometry approach was applied to analyze control, follicular adenoma, and follicular carcinoma using formalin-fixed, paraffin-embedded tissue samples...
July 11, 2017: Journal of Proteomics
https://www.readbyqxmd.com/read/28707625/bioprinting-of-functional-vascularized-mouse-thyroid-gland-construct
#10
Elena A Bulanova, Elizaveta V Koudan, Jonathan Degosserie, Charlotte Heymans, Frederico DAS Pereira, Vladislav A Parfenov, Yi Sun, Qi Wang, Suraya A Akhmedova, Irina K Sviridova, Natalia S Sergeeva, Georgy A Frank, Yusef D Khesuani, Christophe E Pierreux, Vladimir A Mironov
Bioprinting can be defined as additive biofabrication of 3D tissues and organ constructs using tissue spheroids, capable of self-assembly, as building blocks. Thyroid gland, a relatively simple endocrine organ, is suitable for testing the proposed bioprinting technology. Here we report the bioprinting of functional vascularized mouse thyroid gland construct from embryonic tissue spheroids as a proof of concept. Based on the self-assembly principle, we generated thyroid tissue starting from thyroid spheroids (TS) and allantoic spheroids (AS), as a source of thyrocytes and endothelial cells (EC), respectively...
July 14, 2017: Biofabrication
https://www.readbyqxmd.com/read/28704099/long-term-outcomes-and-prognostic-factors-in-patients-with-differentiated-thyroid-cancer-and-distant-metastases
#11
Dania Hirsch, Sigal Levy, Gloria Tsvetov, Alexander Gorstein, Ilana Slutzky-Shraga, Amit Akirov, Eyal Robenshtok, Ilan Shimon, Carlos A Benbassat
OBJECTIVE: Distant metastatic spread is the most frequent cause of thyroid cancer-related death. The objective of this study was to evaluate overall and disease-related survival of patients with differentiated thyroid cancer (DTC) and distant metastases (DM) attending a single medical center and to investigate variables predictive of better long-term outcomes. METHODS: The Rabin Medical Center Thyroid Cancer Registry was searched for patients with DM from DTC. RESULTS: The cohort included 138 patients (58...
July 13, 2017: Endocrine Practice
https://www.readbyqxmd.com/read/28704097/managing-thyroid-tumors-diagnosed-as-non-invasive-follicular-tumor-with-papillary-like-nuclear-features-niftp
#12
Zubair W Baloch, R Mack Harrell, Elise M Brett, Gregory Randolph, Jeffrey R Garber
This commentary summarizes the history and reclassification of noninvasive follicular thyroid tumor with papillary like nuclei (NIFTP). The salient histopathologic features, which are based on immunohistochemical and molecular profiles and serve as inclusion and exclusion criteria are reviewed. The authors also provide their own point of view regarding the practical issues and possible concerns that may be raised by both clinicians and patients based on the diagnosis of NIFTP.
July 13, 2017: Endocrine Practice
https://www.readbyqxmd.com/read/28703115/incidental-diagnosis-of-the-tall-cell-variant-of-the-papillary-microcarcinoma-of-the-thyroid-gland-requires-completion-lymphadenectomy-case-report
#13
I Bartella, F Meyer, K Frauenschläger, K Reschke, Th Wallbaum, B Buth, C Bruns, C Chiapponi
Papillary thyroid carcinoma is the most common neoplasm of the thyroid gland which is usually associated with a very good prognosis. The aim of this case report is to present the disease course of a rare tumor of the thyroid gland, which is worthwhile due to its extraordinary appearance and specific management. A 46-year-old patient presented with a pronounced right-sided, but bilateral, multinodular goiter, with a volume of approximately 80 mL, as assessed on ultrasonography. Surgical removal was indicated as scintigraphy showed a 4-cm cold nodule that almost completely took up the right thyroid lobe...
June 30, 2017: Polski Przeglad Chirurgiczny
https://www.readbyqxmd.com/read/28701827/malignancy-rate-in-thyroid-nodules-categorized-as-atypia-of-undetermined-significance-or-follicular-lesion-of-undetermined-significance-an-institutional-experience
#14
Smita Chandra, Harish Chandra, Sampan S Bisht
INTRODUCTION: Atypia of undetermined significance (AUS) or follicular lesion of undetermined significance (FLUS) of Bethesda system for reporting thyroid cytopathology has emerged as most controversial category due to its heterogeneity and inconsistent usage. Initially associated risk of malignancy was estimated to be about 5-15%, but eventually different results have been obtained across institutions due to variable follow-ups and interpretation. The present study was conducted to evaluate the rate of malignancy along with appropriate management in this category...
July 2017: Journal of Cytology
https://www.readbyqxmd.com/read/28701709/psma-expression-by-microvasculature-of-thyroid-tumors-potential-implications-for-psma-theranostics
#15
Andrey Bychkov, Usanee Vutrapongwatana, Supatporn Tepmongkol, Somboon Keelawat
Prostate-specific membrane antigen (PSMA) is overexpressed in prostate cancer epithelium, making it a promising target for molecular imaging and therapy. Recently, several studies found unexpected PSMA radiotracer uptake by thyroid tumors, including radioiodine-refractory (RAIR) cancers. PSMA expression was reported in tumor-associated endothelium of various malignancies, however it has not been systematically addressed in thyroid tumors. We found that PSMA was frequently expressed in microvessels of thyroid tumors (120/267), but not in benign thyroid tissue...
July 12, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28699989/deaths-related-to-differentiated-thyroid-cancer-a-rare-but-real-event
#16
Ana Kober N Leite, Beatriz G Cavalheiro, Marco Aurélio Kulcsar, Ana de Oliveira Hoff, Lenine G Brandão, Claudio Roberto Cernea, Leandro L Matos
Objective: The present study describes the clinical and tumor characteristics of patients that died from differentiated thyroid cancer and reports on the cause and circumstances of death in these cases. Subjects and methods: Retrospective analysis of all the differentiated thyroid cancer (DTC) related deaths at a single institution over a 5-year period, with a total of 33 patients. Results: Most of the patients were female (63.6%), with a mean age at diagnosis of 58...
May 2017: Archives of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/28699414/role-of-ultrasound-in-predicting-tumor-invasiveness-in-follicular-variant-of-papillary-thyroid-carcinoma
#17
Soo Yeon Hahn, Jung Hee Shin, Young Lyun Oh, Tae Hyuk Kim, Yaeji Lim, Ji Soo Choi
BACKGROUND: Follicular variant of papillary thyroid carcinoma (FVPTC) is traditionally divided into infiltrative and encapsulated types. Adding to this classification, noninvasive follicular thyroid neoplasm with papillary like nuclear features (NIFTP) represents a reclassification of a subset of cases (encapsulated tumors without lymphovascular or capsular invasion). The purpose of this study was to assess the role of ultrasound (US) in predicting tumor invasiveness in FVPTC. METHODS: From January 2014 to May 2016, preoperative US examinations were performed on 151 patients with 152 FVPTCs who underwent surgery...
July 12, 2017: Thyroid: Official Journal of the American Thyroid Association
https://www.readbyqxmd.com/read/28696837/japanese-quail-coturnix-japonica-liver-and-thyroid-gland-histopathology-as-a-result-of-in-ovo-exposure-to-the-flame-retardants-tris-1-3-dichloro-2-propyl-phosphate-and-dechlorane-plus
#18
Mona L Jacobsen, Veerle L B Jaspers, Tomasz M Ciesielski, Bjørn M Jenssen, Mari E Løseth, Nathalie Briels, Igor Eulaers, Páll S Leifsson, Frank F Rigét, Pilar Gomez-Ramirez, Christian Sonne
Japanese quails (Coturnix japonica) were exposed in ovo to tris(1,3-dichloro-2-propyl) phosphate (TDCIPP; 500 ng/µl), Dechlorane Plus (DP; 500 ng/µl), or a 1:1 mixture of these two to investigate the effects on liver and thyroid gland morphology. Histological examination of 14-day-old quails showed that exposure to TDCIPP or the mixture induced hepatic sinusoidal dilatation. No marked effects were seen for DP alone. In addition, the mixture produced divergence of thyroid gland follicles and proliferation of follicular cells...
July 11, 2017: Journal of Toxicology and Environmental Health. Part A
https://www.readbyqxmd.com/read/28695175/follicular-thyroid-carcinoma-presenting-as-large-solitary-vertebral-metastasis-report-of-two-unusual-cases-treated-with-radiotherapy
#19
Neelam Sharma, Abhishek Purkayastha
Solitary spinal metastasis with cord compression as the presenting feature of follicular thyroid carcinoma (FTC) is extremely unusual with <10 cases reported in world literature. We hereby present two such cases in a 39-year-old male with lytic lesion left sacral bone with biopsy showing metastatic carcinoma with morphology and immunophenotype of thyroid gland and a 35-year-old female with thoracic vertebral lesions suggestive of metastatic deposit of FTC. Subsequently, both patients were found to have a solitary nodule in the thyroid lobe...
July 2017: Asia-Pacific Journal of Oncology Nursing
https://www.readbyqxmd.com/read/28692457/the-thyroid-cancer-epidemic-2017-perspective
#20
Benjamin R Roman, Luc G Morris, Louise Davies
PURPOSE OF REVIEW: Thyroid cancer incidence and mortality trends have been identified as being consistent with overdiagnosis, and several recent efforts have been made to mitigate this problem. RECENT FINDINGS: Major guidelines for thyroid nodule management recommend against general biopsy of nodules less than 1 cm in size. Data supporting the safety of active surveillance of low-risk thyroid cancers is now recognized. Tumors previously labeled as encapsulated follicular variant papillary thyroid cancers are now recommended to be called noninvasive follicular thyroid neoplasm with papillary-like nuclear features...
July 7, 2017: Current Opinion in Endocrinology, Diabetes, and Obesity
keyword
keyword
54861
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"